CN109620919A - A kind of Chinese materia medica preparation and preparation method thereof for treating osteopathy - Google Patents

A kind of Chinese materia medica preparation and preparation method thereof for treating osteopathy Download PDF

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CN109620919A
CN109620919A CN201811608637.3A CN201811608637A CN109620919A CN 109620919 A CN109620919 A CN 109620919A CN 201811608637 A CN201811608637 A CN 201811608637A CN 109620919 A CN109620919 A CN 109620919A
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parts
materia medica
water
chinese materia
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赵钰
冯仕林
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/898—Orchidaceae (Orchid family)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

Abstract

The invention discloses a kind of Chinese materia medica preparation for treating osteopathy, 1-8 parts of river ox paint, 1-6 parts of Cortex Eucommiae, 60-100 parts of Radix Salviae Miltiorrhizae, 1-5 parts of Rhizoma Gastrodiae, 50-100 parts of Chinese coriaria root, 3-9 parts of Canton love-pea vine, 2-8 parts of Herba Cistanches, 3-7 parts of scorpio, 12-16 parts of honey, 1-5 parts of champion bauhinia root, 10-18 parts of red ginseng, 6-18 parts of the rhizome of davallia, 4-15 parts of rhizoma homalonemae, 8-18 parts of lycopodium calvatum, brave tail wheel 14-32 parts, 1-6 parts of elder, 1-6 parts of Radix Astragali, 10-25 parts of myrrh, 0.5-3 parts of preservative.Chinese materia medica preparation of the invention has strengthening vital energy of kidney bone strengthening, train liver nourishing the muscle and tendon dredging collateral, activating microcirculation and removing stasis medicinal swelling and pain relieving, enhance bone density and other effects, it can reach promoting blood circulation within a short period of time, swelling and pain relieving, the effect of promoting body tissue healing and bone tissue growth, so that patient is eliminated the pain of blood stasis and swelling pain within a short period of time, accelerates the recovery from illness of the osteopathy such as fracture, traumatic injury.

Description

A kind of Chinese materia medica preparation and preparation method thereof for treating osteopathy
Technical field
The present invention relates to field of medicaments, and in particular to a kind of Chinese materia medica preparation and preparation method thereof for treating osteopathy.
Background technique
Orthopaedic disease is the common disease of current integrative therapy, though treatment method both domestic and external is more, effect is unsatisfactory: Western medical treatment mostly use operation etc. physiotherapies and oral western medicine treatment etc., operation etc. physiotherapies wound it is big, recovery time compared with Long, some patients cannot receive；Oral western medicine treatment time, long side effect was larger, the pairs such as impaired to gastrointestinal irritation, hepatic and renal function Effect；The effect of existing Chinese materia medica preparation can not reach promoting blood circulation within a short period of time, swelling and pain relieving.
The Chinese materia medica preparation of existing similar treatment orthopaedic disease is common to have Gukang capsule, sanqi shangyao tablets, sanqi shangyao pian, Yunnan white Medicine, Qili San, Dieda Wan etc. have preferable swelling and pain relieving in clinical application, promote body tissue healing and growth of spur And other effects, but that there are effective speed is slow, the course for the treatment of is long, since the course of disease is too long, to make injury region muscle, the different journeys of ligament nerve The disadvantages of loss of degree.If the average healing of " sanqi tablets " for fracture is 49 days, promoting union rate is 87%；Have Drug also need to be taken with yellow rice wine, therefore, affect the treatment of patient with bone fracture, extend treatment time, increase the pain of patient It is bitter.
Summary of the invention
It is an object of the invention to overcome defect of the existing technology, when bone healing can be obviously shortened by providing one kind Between.
To achieve the goals above, The technical solution adopted by the invention is as follows:
A kind of Chinese materia medica preparation for treating osteopathy, is prepared by the raw material of following parts by weight: 1-8 parts of river ox paint, Cortex Eucommiae 1-6 parts, 60-100 parts of Radix Salviae Miltiorrhizae, 1-5 parts of Rhizoma Gastrodiae, 50-100 parts of Chinese coriaria root, 3-9 parts of Canton love-pea vine, 2-8 parts of Herba Cistanches, scorpio 3-7 Part, 12-16 parts of honey, 1-5 parts of champion bauhinia root, 10-18 parts of red ginseng, 6-18 parts of the rhizome of davallia, 4-15 parts of rhizoma homalonemae, lycopodium calvatum 8-18 Part, brave tail wheel 14-32 parts, 1-6 parts of elder, 1-6 parts of Radix Astragali, 10-25 parts of myrrh, 0.5-3 parts of preservative.
Further, it is prepared by the raw material of following parts by weight: 2-6 parts of river ox paint, 2-5 parts of Cortex Eucommiae, Radix Salviae Miltiorrhizae 75-85 Part, 2-4 parts of Rhizoma Gastrodiae, 70-90 parts of Chinese coriaria root, 4-6 parts of Canton love-pea vine, 4-6 parts of Herba Cistanches, 4-6 parts of scorpio, 13-15 parts of honey, Kowloon It 2-4 parts of root, 12-16 parts of red ginseng, 8-14 parts of the rhizome of davallia, 6-10 parts of rhizoma homalonemae, 10-14 parts of lycopodium calvatum, brave tail wheel 20-25 parts, connects 2-5 parts of bone wood, 2-5 parts of Radix Astragali, 15-20 parts of myrrh, 1-2 parts of preservative.
Further, the active constituent of the Chinese materia medica preparation is by mentioning a part of raw water, a part of raw material crush and Surplus stock steeping in wine is mixed with after extracting.
Further, a part of raw water mention in raw material include river ox paint, Cortex Eucommiae, Radix Salviae Miltiorrhizae, Chinese coriaria root, chicken bone Grass, Herba Cistanches, honey, champion bauhinia root, red ginseng, the rhizome of davallia, rhizoma homalonemae, lycopodium calvatum, brave tail wheel, elder, Radix Astragali, the water, which mentions, is Medicinal material is cut into medicine materical crude slice into the water, is added water to submerge, heating releases a water cooking liquid after carrying out a boiling, then plus equivalent water Secondary water cooking liquid is released after carrying out secondary boiling, filters, is being concentrated to give after a water cooking liquid and secondary water cooking liquid are mixed To water extracting liquid.
Further, the amount of water is 3-8 times of medicinal raw material volume, the time of a boiling and secondary boiling Identical and be 1-3h, the strainer mesh number of the filtering is 100-300 mesh, and the concentration is by a water cooking liquid and secondary water cooking liquid One third is condensed into after mixing.
Further, the raw material in a part of raw material crushing is Rhizoma Gastrodiae, and described crush is first that Rhizoma Gastrodiae is abundant After net system drying, carry out being ground into powder using wall-breaking machine.
Further, the temperature of the drying is 80-130 DEG C, and the mesh number that the Rhizoma Gastrodiae crushes is 60-100 mesh.
Further, the raw material in the surplus stock steeping in wine is myrrh and scorpio, and the steeping in wine is to be put into raw material It measures after being impregnated in white wine, steeping in wine extracting solution is obtained by filtration.
Further, the degree of the white wine is 40-60 °, and the amount of the white wine is that 5-7 times of medicinal material volume is measured, the leaching The time of bubble is 5-12 days.
Further, a kind of Chinese materia medica preparation for treating osteopathy according to claim 1, it is characterised in that: described anti- Rotten agent is sorbic acid.
It is raw material effect of Chinese materia medica preparation of the present invention below:
River ox paint: return liver and kidney channel；Dispelling stasis of blood and stimulating the menstrual flow, it is easing joint movement；For injury from falling down, rheumatoid arthrosis numbness pain, sufficient impotence muscle contraction Deng.
Cortex Eucommiae: return liver and kidney channel；Nourishing liver and kidney, strong waist knee, strengthening the bones and muscles；For kidney deficiency and liver, soreness of waist and knee joint, muscles and bones is powerless, foot Knee flaccidity etc..
Radix Salviae Miltiorrhizae: converge to heart and liver channels；Promoting blood circulation, inducing meastruation to relieve menalgia, cool blood to disappear carbuncle；Yong Yu lumps in the chest and abdomen, hot numbness pain, sore Swelling and pain etc..
Rhizoma Gastrodiae: return liver warp；Subduing inflammation, dispelling wind and removing obstruction in the meridians, promoting blood circulation, benifit waist and knees, strengthening tendons power；For extremity numbness, rheumatism numbness Pain etc..
Chinese coriaria root: return lung, Liver Channel；Dispelling wind and eliminating dampness, analgesia；For rheumatic numbness, traumatic injury etc..
Canton love-pea vine: for the drying complete stool of leguminous plant abrus cantoniensis Hance.Sweet, slight bitter, it is cool.There is removing dampness through diuresis and removing jaundice, it is clearing heat and detoxicating, The effect of dispersing the depressed liver-qi and alleviating pain.
Herba Cistanches: for the fleshy stem of the dry zone scale leaf of orobanchaceae plant cistanche.It is sweet in flavor, salty, it is warm-natured；Return kidney, large intestine Through；Kidney-replenishing, benefiting essence-blood, relax bowel and defecation.
Scorpio: for the hirudo leech of Buthidae animal buthus martensii Karscs.Acrid flavour, it is mild-natured；Return liver warp；Relieve the wind syndrome antispastic, dispersing pathogen accumulation, It removes obstruction in channels to relieve pain.
Honey: can cool blood detumescence, activating microcirculation and removing stasis medicinal, mental-tranquilization, relieving restlessness and restlessness.
Champion bauhinia root: wind-damp dispelling, promoting circulation of blood gas.Control traumatic injury, treating rheumatic ostealgia, heart and stomach pain.
Red ginseng: matter is hard, weight and crisp, gas perfume, mildly bitter flavor.It to be taken off for physically weak, cold weak pulse of limb is Qi dysfunction in blood control, under metrorrhagia and metrostaxis Blood；Heart failure, cardiogenic shock.
The rhizome of davallia: rhizome of davallia rhizomes is used as medicine, rich in the effective components such as flavones, alkaloid, phenols, have removing blood stasis and acesodyne, Reunion of bone, toothache, Low Back Pain, chronic diarrhea and other effects.
Rhizoma homalonemae: energy wind-damp dispelling, and energy strengthening the bones and muscles, for rheumatic arthralgia, soft, the brothers' muscular constricture paralysis of soreness of waist foot etc..
Lycopodium calvatum: there is the effect of dispelling wind and eliminating dampness, relaxing tendons and activating collaterals.
Brave tail wheel: sweet, slight bitter is put down.Return heart, lung, Liver Channel.Clearing lung and relieving cough, dissipating stasis and stanching bleeding.Cough is controlled, pulmonary abscess is spitted blood, coughed up Blood, hematuria, rectal prolapse, uterine prolapse, pyogenic infections.
Elder: it is sweet in flavor, bitter, it puts down；Return liver warp.Major function: reunion of bone, promoting blood circulation and stopping pain, expelling wind and removing dampness.For bone Folding, traumatic injury, rheumatic arthritis, gout, Kaschin-Beck disease, acute and chronic ephritis；Wound hemorrhage is controlled in external application.
Radix Astragali, the entitled Leguminosae of Latin, alias astragali, northern alpine yarrow, Astragalus, be leguminous herbaceous plant's astragalus mongolicus, The dry root of Astragalus membranacus.It is warm-natured, sweet in flavor, slightly sweet.With with invigorating qi, consolidating exterior, promoting urination and detoxification, apocenosis, the work of expelling pus and promoting granulation With.
Myrrh: there is the effect of scattered stasis pain, detumescence and promoting granulation.It is usually used in chest impediment and cardialgia, gastral cavity pain, dysmenorrhea menostasis produces Stasis blocking , abdominal mass and abdominal pain afterwards, rheumatic arthralgia, traumatic injury, the treatment of the illnesss such as carbuncle swells sore.
TCM Preparation Room disclosed by the invention combine traditional Chinese medicine traditional theory with modern science, through a large amount of scientific experiments Drug, the optimum formula of composition are screened with clinical observation, and uses traditional handicraft, keeps original Chinese medicine to integrate ingredient effect, through medicine Prison department is approved as hospital preparation, proves by the clinical use of many years, which makes all types of fresh fractures, traumatic injury At the bones such as blood stasis and swelling pain, old fracture, caput femoris necrosis, neck protrusion of lumbar vertebral disc, knee joint degeneration, scapulohumeral periarthritis Arthropathy has significant curative effect, and the present invention solves all disadvantages of the prior art, has that wound is small, Small side effects, analgesic is fast, disappears Swollen feature fast, healing is fast: having energy rapid pain relief after medication, the quickly alleviating pain effect that pain is substantially reduced after 24 hours Fruit；Have after medication and significantly eliminates soft tissue swelling, the effect for promoting the detumescence of absorption of hematoma fast.River ox paint is used in we Injury from falling down, rheumatoid arthrosis numbness pain, sufficient impotence muscle contraction, myrrh has scattered stasis pain, the effect of detumescence and promoting granulation, elder can synthetism it is continuous Muscle, promoting blood circulation and stopping pain, expelling wind and removing dampness, this three are monarch drug in a prescription；Cortex Eucommiae can treat soreness of waist and knee joint, and muscles and bones is powerless, and foot and knee flaccidity, Radix Salviae Miltiorrhizae can Promoting blood circulation, inducing meastruation to relieve menalgia, Rhizoma Gastrodiae can reduce swelling wind-dispelling, strengthening tendons power, scorpio energy relieve the wind syndrome antispastic, and dispersing pathogen accumulation is removed obstruction in channels to relieve pain, bone Broken mend has removing blood stasis and acesodyne, reunion of bone and other effects, this is ministerial drug；Chinese coriaria root treats traumatic injury, and champion bauhinia root, which can be controlled, to fall Play damage, treating rheumatic ostealgia, both this is adjutant, remaining component can relaxing tendons and activating collaterals, tonifying Qi solid etc., to make medicine.
The present invention is by adopting the above-described technical solution, have the advantages that
(1) three kinds of situation processing of raw material point can be selected according to the property of medicine material in preparation method of the invention Extraction medium is that raw material active constituent sufficiently releases；
(1) present invention combines traditional Chinese medicine traditional theory with modern science, sieves through a large amount of scientific experiments and clinical observation Select drug, the optimum formula of composition；And with traditional handicraft, the comprehensive ingredient effect of original Chinese medicine is kept, is approved as through drug administration department Hospital preparation；The Chinese materia medica preparation of the invention blood stasis and swelling pain caused by all types of fresh fractures, traumatic injury, old fracture, The orthopaedic diseases such as caput femoris necrosis, neck protrusion of lumbar vertebral disc, knee joint degeneration, scapulohumeral periarthritis have and relieve pain fast, detumescence Fastly, fast feature is cured, there is strengthening vital energy of kidney bone strengthening, trains liver nourishing the muscle and tendon dredging collateral, activating microcirculation and removing stasis medicinal swelling and pain relieving, the function such as enhancing bone density Effect.
(2) Chinese materia medica preparation of the invention clinical tests prove that, have medication after can rapid pain relief, ache after 24 hours Bitterly substantially reduced quickly alleviating pain effect；Have after medication and significantly eliminate soft tissue swelling, promotes the detumescence of absorption of hematoma fast Effect；A large amount of clinical examinations and X-ray confirm that healing time shortens the 1/2-3/4 time than routine treatment, can be shorter Reach promoting blood circulation in time, swelling and pain relieving, enables patient shorter at the effect of promoting body tissue healing and bone tissue growth The pain that blood stasis and swelling pain is eliminated in time, accelerates the recovery from illness of the osteopathy such as fracture, traumatic injury, and clinical use is safe and reliable.
(3) Chinese medicine composition of the invention and its pharmaceutical formulation are scientific and reasonable, and Small side effects, preparation method is simple, preparation It is at low cost, body and the financial burden of patient can be mitigated significantly, there is very big promotional value.
Detailed description of the invention
Fig. 1 is a kind of preparation method flow chart of the liquor of Chinese materia medica preparation for treating osteopathy of the invention；
Fig. 2 is the preparation method process of a kind of tablet of Chinese materia medica preparation for treating osteopathy of the invention, granule and capsule Figure.
Specific embodiment
To make the objectives, technical solutions, and advantages of the present invention more comprehensible, preferred embodiment is enumerated below, to this hair Bright further description.However, it is necessary to illustrate, many details listed in specification are used for the purpose of making reader to this The one or more aspects of invention have a thorough explanation, also may be implemented even without these specific details of the invention These aspects.
Embodiment 1
A kind of Chinese materia medica preparation for treating osteopathy, is prepared by the raw material of following parts by weight: 1 part of river ox paint, Cortex Eucommiae 1 Part, 60 parts of Radix Salviae Miltiorrhizae, 1 part of Rhizoma Gastrodiae, 50 parts of Chinese coriaria root, 3 parts of Canton love-pea vine, 2 parts of Herba Cistanches, 3 parts of scorpio, 12 parts of honey, champion bauhinia root 1 Part, 10 parts of red ginseng, 6 parts of the rhizome of davallia, 4 parts of rhizoma homalonemae, 8 parts of lycopodium calvatum, 14 parts of brave tail wheel, 1 part of elder, 1 part of Radix Astragali, myrrh 10 Part, 0.5 part of preservative, preservative is sorbic acid.
The active constituent of Chinese materia medica preparation is by mentioning a part of raw water, and a part of raw material crushes and surplus stock steeping in wine mentions It is mixed with after taking.A part of raw water mention in raw material include river ox paint, Cortex Eucommiae, Radix Salviae Miltiorrhizae, Chinese coriaria root, Canton love-pea vine, meat Desert cistanche, honey, champion bauhinia root, red ginseng, the rhizome of davallia, rhizoma homalonemae, lycopodium calvatum, brave tail wheel, elder, Radix Astragali, it is by medicine that the water, which mentions, Material is cut into medicine materical crude slice into the water, and water is added to prohibit submergence, and amount of water is 3 times of medicinal raw material volume, and heating is put after carrying out a boiling A water cooking liquid out, then plus equivalent water carry out secondary boiling after release secondary water cooking liquid, by a water cooking liquid and secondary boiling It is filtered after liquid mixing, is being concentrated to give water extracting liquid, a boiling is mutually all 1h with the time of secondary boiling, institute The strainer mesh number for stating filtering is 100 mesh, the concentration for will a water cooking liquid and secondary water cooking liquid mix after be condensed into three/ One；Raw material in a part of raw material crushing is Rhizoma Gastrodiae, and described crush is after first sufficiently drying Rhizoma Gastrodiae, wall-breaking machine to be used to carry out powder It is broken into powder, the temperature of drying is 80 DEG C, and the mesh number that the Rhizoma Gastrodiae crushes is 60 mesh；Raw material in surplus stock steeping in wine is myrrh And scorpio, the steeping in wine are put into raw material in excessive white wine after immersion, the degree that steeping in wine extracting solution white wine is obtained by filtration is 40 °, the amount of the white wine is 5 times of medicinal material volume, and the time of the immersion is 5 days.
Embodiment 2
A kind of Chinese materia medica preparation for treating osteopathy, is prepared by the raw material of following parts by weight: 8 parts of river ox paint, Cortex Eucommiae 6 Part, 100 parts of Radix Salviae Miltiorrhizae, 5 parts of Rhizoma Gastrodiae, 100 parts of Chinese coriaria root, 9 parts of Canton love-pea vine, 8 parts of Herba Cistanches, 7 parts of scorpio, 16 parts of honey, champion bauhinia root 5 Part, 18 parts of red ginseng, 18 parts of the rhizome of davallia, 15 parts of rhizoma homalonemae, 18 parts of lycopodium calvatum, 32 parts of brave tail wheel, 6 parts of Radix Astragali, does not have by 6 parts of elder 25 parts of medicine, 3 parts of preservative, preservative is sorbic acid.
The active constituent of Chinese materia medica preparation is by mentioning a part of raw water, and a part of raw material crushes and surplus stock steeping in wine mentions It is mixed with after taking.A part of raw water mention in raw material include river ox paint, Cortex Eucommiae, Radix Salviae Miltiorrhizae, Chinese coriaria root, Canton love-pea vine, meat Desert cistanche, honey, champion bauhinia root, red ginseng, the rhizome of davallia, rhizoma homalonemae, lycopodium calvatum, brave tail wheel, elder, Radix Astragali, it is by medicine that the water, which mentions, Material is cut into medicine materical crude slice into the water, and water is added to prohibit submergence, and amount of water is 8 times of medicinal raw material volume, and heating is fallen after carrying out a boiling A water cooking liquid out, then plus equivalent water carry out secondary boiling after pour out secondary water cooking liquid, by a water cooking liquid and secondary boiling It is filtered after liquid mixing, is being concentrated to give water extracting liquid, a boiling is mutually all 3h with the time of secondary boiling, institute The strainer mesh number for stating filtering is 300 mesh, the concentration for will a water cooking liquid and secondary water cooking liquid mix after be condensed into three/ One；Raw material in a part of raw material crushing is Rhizoma Gastrodiae, and described crush is after first sufficiently drying Rhizoma Gastrodiae, wall-breaking machine to be used to carry out powder It is broken into powder, the temperature of drying is 130 DEG C, and the mesh number that the Rhizoma Gastrodiae crushes is 100 mesh；Raw material in surplus stock steeping in wine is that do not have Medicine and scorpio, the steeping in wine are put into raw material in excessive white wine after immersion, and the degree that steeping in wine extracting solution white wine is obtained by filtration is 60 °, the amount of the white wine is 7 times of medicinal material volume, and the time of the immersion is 12 days.
Embodiment 3
A kind of Chinese materia medica preparation for treating osteopathy, is prepared by the raw material of following parts by weight: 2 parts of river ox paint, Cortex Eucommiae 2 Part, 75 parts of Radix Salviae Miltiorrhizae, 2 parts of Rhizoma Gastrodiae, 70 parts of Chinese coriaria root, 4 parts of Canton love-pea vine, 4 parts of Herba Cistanches, 4 parts of scorpio, 13 parts of honey, champion bauhinia root 2 Part, 12 parts of red ginseng, 8 parts of the rhizome of davallia, 6 parts of rhizoma homalonemae, 10 parts of lycopodium calvatum, 20 parts of brave tail wheel, 2 parts of elder, 2 parts of Radix Astragali, myrrh 15-20 parts, 1 part of preservative.
The active constituent of Chinese materia medica preparation is by mentioning a part of raw water, and a part of raw material crushes and surplus stock steeping in wine mentions It is mixed with after taking.A part of raw water mention in raw material include river ox paint, Cortex Eucommiae, Radix Salviae Miltiorrhizae, Chinese coriaria root, Canton love-pea vine, meat Desert cistanche, honey, champion bauhinia root, red ginseng, the rhizome of davallia, rhizoma homalonemae, lycopodium calvatum, brave tail wheel, elder, Radix Astragali, it is by medicine that the water, which mentions, Material is cut into medicine materical crude slice into the water, and water is added to prohibit submergence, and amount of water is 4 times of medicinal raw material volume, and heating is fallen after carrying out a boiling A water cooking liquid out, then plus equivalent water carry out secondary boiling after pour out secondary water cooking liquid, by a water cooking liquid and secondary boiling It is filtered after liquid mixing, is being concentrated to give water extracting liquid, a boiling is mutually all 2h with the time of secondary boiling, institute The strainer mesh number for stating filtering is 200 mesh, the concentration for will a water cooking liquid and secondary water cooking liquid mix after be condensed into three/ One；Raw material in a part of raw material crushing is Rhizoma Gastrodiae, and described crush is after first sufficiently drying Rhizoma Gastrodiae, wall-breaking machine to be used to carry out powder It is broken into powder, the temperature of drying is 80 DEG C, and the mesh number that the Rhizoma Gastrodiae crushes is 80 mesh；Raw material in surplus stock steeping in wine is myrrh And scorpio, the steeping in wine are put into raw material in excessive white wine after immersion, the degree that steeping in wine extracting solution white wine is obtained by filtration is 50 °, the amount of the white wine is 6 times of medicinal material volume, and the time of the immersion is 7 days.
Embodiment 4
A kind of Chinese materia medica preparation for treating osteopathy, is prepared by the raw material of following parts by weight: 6 parts of river ox paint, Cortex Eucommiae 5 Part, 85 parts of Radix Salviae Miltiorrhizae, 4 parts of Rhizoma Gastrodiae, 90 parts of Chinese coriaria root, 6 parts of Canton love-pea vine, 6 parts of Herba Cistanches, 6 parts of scorpio, 15 parts of honey, champion bauhinia root 4 Part, 16 parts of red ginseng, 14 parts of the rhizome of davallia, 10 parts of rhizoma homalonemae, 14 parts of lycopodium calvatum, 25 parts of brave tail wheel, 5 parts of Radix Astragali, does not have by 5 parts of elder 18 parts of medicine, 2 parts of preservative.
The active constituent of Chinese materia medica preparation is by mentioning a part of raw water, and a part of raw material crushes and surplus stock steeping in wine mentions It is mixed with after taking.A part of raw water mention in raw material include river ox paint, Cortex Eucommiae, Radix Salviae Miltiorrhizae, Chinese coriaria root, Canton love-pea vine, meat Desert cistanche, honey, champion bauhinia root, red ginseng, the rhizome of davallia, rhizoma homalonemae, lycopodium calvatum, brave tail wheel, elder, Radix Astragali, it is by medicine that the water, which mentions, Material is cut into medicine materical crude slice into the water, and water is added to prohibit submergence, and amount of water is 6 times of medicinal raw material volume, and heating is fallen after carrying out a boiling A water cooking liquid out, then plus equivalent water carry out secondary boiling after pour out secondary water cooking liquid, by a water cooking liquid and secondary boiling It is filtered after liquid mixing, is being concentrated to give water extracting liquid, a boiling is mutually all 3h with the time of secondary boiling, institute The strainer mesh number for stating filtering is 250 mesh, the concentration for will a water cooking liquid and secondary water cooking liquid mix after be condensed into three/ One；Raw material in a part of raw material crushing is Rhizoma Gastrodiae, and described crush is after first sufficiently drying Rhizoma Gastrodiae, wall-breaking machine to be used to carry out powder It is broken into powder, the temperature of drying is 100 DEG C, and the mesh number that the Rhizoma Gastrodiae crushes is 100 mesh；Raw material in surplus stock steeping in wine is that do not have Medicine and scorpio, the steeping in wine are put into raw material in excessive white wine after immersion, and the degree that steeping in wine extracting solution white wine is obtained by filtration is 60 °, the amount of the white wine is 5 times of medicinal material volume, and the time of the immersion is 10 days.
Embodiment 5
A kind of Chinese materia medica preparation for treating osteopathy, is prepared by the raw material of following parts by weight: 3 parts of river ox paint, Cortex Eucommiae 3 Part, 80 parts of Radix Salviae Miltiorrhizae, 3 parts of Rhizoma Gastrodiae, 80 parts of Chinese coriaria root, 5 parts of Canton love-pea vine, 5 parts of Herba Cistanches, 5 parts of scorpio, 14 parts of honey, champion bauhinia root 3 Part, 15 parts of red ginseng, 12 parts of the rhizome of davallia, 8 parts of rhizoma homalonemae, 12 parts of lycopodium calvatum, 23 parts of brave tail wheel, 3 parts of elder, 3 parts of Radix Astragali, myrrh 18 parts, 2 parts of preservative.
The active constituent of Chinese materia medica preparation is by mentioning a part of raw water, and a part of raw material crushes and surplus stock steeping in wine mentions It is mixed with after taking.A part of raw water mention in raw material include river ox paint, Cortex Eucommiae, Radix Salviae Miltiorrhizae, Chinese coriaria root, Canton love-pea vine, meat Desert cistanche, honey, champion bauhinia root, red ginseng, the rhizome of davallia, rhizoma homalonemae, lycopodium calvatum, brave tail wheel, elder, Radix Astragali, it is by medicine that the water, which mentions, Material is cut into medicine materical crude slice into the water, and water is added to prohibit submergence, and amount of water is 5 times of medicinal raw material volume, and heating is fallen after carrying out a boiling A water cooking liquid out, then plus equivalent water carry out secondary boiling after pour out secondary water cooking liquid, by a water cooking liquid and secondary boiling It is filtered after liquid mixing, is being concentrated to give water extracting liquid, a boiling is mutually all 3h with the time of secondary boiling, institute The strainer mesh number for stating filtering is 250 mesh, the concentration for will a water cooking liquid and secondary water cooking liquid mix after be condensed into three/ One；Raw material in a part of raw material crushing is Rhizoma Gastrodiae, and described crush is after first sufficiently drying Rhizoma Gastrodiae, wall-breaking machine to be used to carry out powder It is broken into powder, the temperature of drying is 100 DEG C, and the mesh number that the Rhizoma Gastrodiae crushes is 80 mesh；Raw material in surplus stock steeping in wine is that do not have Medicine and scorpio, the steeping in wine are put into raw material in excessive white wine after immersion, and the degree that steeping in wine extracting solution white wine is obtained by filtration is 50 °, the amount of the white wine is 7 times of medicinal material volume, and the time of the immersion is 8 days.
Clinical test is summarized
1, basic document
360 clinical observations of fracture or traumatic injury patient made a definite diagnosis are selected, patient is randomly divided into two groups, treatment group 180 Example, wherein male 120, women 120, the age 16~67 years old, average age 43 years old, the course of disease 3 days~4 months, 2 average Month.It is control group 180, the age 13~59 years old, average age 40 years old, the course of disease 2 days~3 months, 1 month average.Two groups of cases The course of disease, degrees of symptoms are almost the same, and no significant difference is comparable.
2, treatment method
Treatment group patient takes Chinese materia medica preparation of the invention, takes orally, 2 tablets each time, a 30mg, and 3 times a day, in the morning, afternoon and evening respectively Once, 5 days as a treatment course, usual 1~4 course for the treatment of recovery from illness, serious person need 5~6 course for the treatment of recoveries from illness.
Control group use sanqi shangyao tablets, sanqi shangyao pian, take orally, one time 3,3 times a day.7 days as a course for the treatment of, or takes when necessary.
3, curative effect judging standard
(1) it cures: fracturing or the symptoms such as damage location pain, the swollen hot, breathing in part are limited disappear；Activity freely, body Recovery from illness.
(2) effectively: above-mentioned symptom is alleviated, and freely, body is fully recovered for activity.
(3) invalid: illness is unchanged.
4, result
By the treatment of 3 courses for the treatment of, clinical efficacy is shown in Table 1.
1 therapeutic effect of table
Grouping Healing/example Effectively/example In vain/example Cure rate/% Total effective rate/%
Treatment group 152 19 9 84.4 95
Control group 103 45 32 57.2 82.2
As it can be seen from table 1 the treatment by 3 courses for the treatment of, Chinese materia medica preparation of the invention controls fracture and traumatic injury More rate is up to 94.4%, total effective rate 95%, and uses the cure rate of the control group of sanqi shangyao tablets, sanqi shangyao pian and total effective rate significantly low In use Chinese materia medica preparation of the invention, it is seen that Chinese materia medica preparation of the present invention can effectively treat fracture or traumatic injury, have strong waist Nourishing disney and strengthening bone, trains liver nourishing the muscle and tendon dredging collateral, activating microcirculation and removing stasis medicinal swelling and pain relieving, and enhancing bone density and other effects shows the present invention by clinical observation Chinese materia medica preparation has significant curative effect to fracture and traumatic injury, and curative effect is rapid, and causes to all types of fresh fractures, traumatic injury The orthopaedics such as blood stasis and swelling pain, old fracture, caput femoris necrosis, neck protrusion of lumbar vertebral disc, knee joint degeneration, scapulohumeral periarthritis Disease has the characteristics that small wound, Small side effects, analgesic is fast, detumescence is fast, cures fast novel Special Traditional Chinese Medicine oral preparation, suffers from Person can generally feel substantially reduced after 1 course for the treatment of of taking medicine or disappear that renal function and hemopoietic system to patient have no different Often variation and adverse reaction, " rebounding " does not occur in the state of an illness after drug withdrawal, and clinic is taken securely and reliably.
Typical case
Case 1: XX, female, 26 years old.
Go on a tour accidentally tumble injury of climbing the mountain of patient leads to fracture of lower leg, and pain is endlessly.Chinese medicine of the present invention is taken after operation is fixed After 1 course for the treatment of of preparation, symptom is relieved, and continues to take 2 course for the treatment of, and clinical symptoms all disappear.There has been no recurrence since follow-up.
Case 2: what X, male, 50 years old.
Patient injures left hand arm bone, limitation of activity because of working principle.It fractures left hands through inspection.This is taken after operation is fixed After 2 courses for the treatment of of invention Chinese materia medica preparation, symptom improves, and after then taking 1 course for the treatment of, physical recovery is normal, and activity is freely.Follow-up is extremely The present does not recur.
Case 3: old XX, male, 65 years old.
Patient slightly fractures because of traffic accident rib cage leads to chest pain, and with cough, the movements such as deep breathing, body rotations add Weight, it is very painful.After taking 2 courses for the treatment of of Chinese materia medica preparation of the present invention after operation is fixed, the above symptom improves, and continues to take 2 treatments Cheng Hou, the above symptom disappear, and body recovery from illness, freely, there has been no recurrence since follow-up for activity.
Case 4: old XX, female, 36 years old.
Patient's traffic accident causes fractured leg, and activity has obstacle, expiratory dyspnea.After carrying out operation fixation, Chinese medicine of the present invention is taken After 1 course for the treatment of of preparation, body gradually rehabilitation, symptom is relieved, and continues to take 1 course for the treatment of, and the above symptom disappears.Follow-up is so far It does not recur.
In summary, treatment osteopathy Chinese medicine preparation treatment effect of the invention is good, healing speed is fast, securely and reliably, It is without side-effects.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For member, without departing from the principle of the present invention, it can also make several improvements and retouch, these improvements and modifications are also answered It is considered as protection scope of the present invention.

Claims (10)

1. a kind of Chinese materia medica preparation for treating osteopathy, it is characterised in that: be prepared by the raw material of following parts by weight: river ox paint 1- 8 parts, 1-6 parts of Cortex Eucommiae, 60-100 parts of Radix Salviae Miltiorrhizae, 1-5 parts of Rhizoma Gastrodiae, 50-100 parts of Chinese coriaria root, 3-9 parts of Canton love-pea vine, 2-8 parts of Herba Cistanches, 3-7 parts of scorpio, 12-16 parts of honey, 1-5 parts of champion bauhinia root, 10-18 parts of red ginseng, 6-18 parts of the rhizome of davallia, 4-15 parts of rhizoma homalonemae, stretch muscle It is 8-18 parts careless, brave tail wheel 14-32 parts, 1-6 parts of elder, 1-6 parts of Radix Astragali, 10-25 parts of myrrh, 0.5-3 parts of preservative.
2. a kind of Chinese materia medica preparation for treating osteopathy according to claim 1, it is characterised in that: by the raw material of following parts by weight It is prepared: 2-6 parts of river ox paint, 2-5 parts of Cortex Eucommiae, 75-85 parts of Radix Salviae Miltiorrhizae, 2-4 parts of Rhizoma Gastrodiae, 70-90 parts of Chinese coriaria root, Canton love-pea vine 4- 6 parts, 4-6 parts of Herba Cistanches, 4-6 parts of scorpio, 13-15 parts of honey, 2-4 parts of champion bauhinia root, 12-16 parts of red ginseng, 8-14 parts of the rhizome of davallia, thousand Year is 6-10 parts strong, and 10-14 parts of lycopodium calvatum, 20~25 parts of brave tail wheel, 2-5 parts of Radix Astragali, 15-20 parts of myrrh, is prevented by 2-5 parts of elder Rotten agent 1-2 parts.
3. a kind of Chinese materia medica preparation for treating osteopathy according to claim 1 or 2, it is characterised in that: the Chinese materia medica preparation By mentioning a part of raw water, a part of raw material is crushed to be mixed with active constituent with after the extraction of surplus stock steeping in wine.
4. a kind of Chinese materia medica preparation for treating osteopathy according to claim 3, it is characterised in that: a part of raw water mentions In raw material include river ox paint, Cortex Eucommiae, Radix Salviae Miltiorrhizae, Chinese coriaria root, Canton love-pea vine, Herba Cistanches, honey, champion bauhinia root, red ginseng, the rhizome of davallia, thousand Nian Jian, lycopodium calvatum, brave tail wheel, elder, Radix Astragali, it is that medicinal material is cut into medicine materical crude slice into the water that the water, which mentions, is added water to submerge, and is heated Carry out releasing a water cooking liquid after a boiling, then plus equivalent water carry out secondary boiling after release secondary water cooking liquid, will be primary It is filtered after water cooking liquid and the mixing of secondary water cooking liquid, is being concentrated to give water extracting liquid.
5. a kind of Chinese materia medica preparation for treating osteopathy according to claim 4, it is characterised in that: the amount of water is that medicinal material is former 3-8 times of Material product, a boiling is identical with the time of secondary boiling and is 1-3h, and the strainer mesh number of the filtering is 100-300 mesh, the concentration for will a water cooking liquid and secondary water cooking liquid mix after be condensed into one third.
6. a kind of Chinese materia medica preparation for treating osteopathy according to claim 3, it is characterised in that: a part of raw material crushes In raw material be Rhizoma Gastrodiae, it is described to crush first by after Rhizoma Gastrodiae abundant net system drying, to carry out being ground into powder using wall-breaking machine.
7. a kind of Chinese materia medica preparation for treating osteopathy according to claim 6, it is characterised in that: the temperature of the drying is 80-130 DEG C, the mesh number that the Rhizoma Gastrodiae crushes is 60-100 mesh.
8. a kind of Chinese materia medica preparation for treating osteopathy according to claim 3, it is characterised in that: in the surplus stock steeping in wine Raw material be myrrh and scorpio, the steeping in wine is that after being put into raw material and impregnating in excessive white wine, steeping in wine extracting solution is obtained by filtration.
9. a kind of Chinese materia medica preparation for treating osteopathy according to claim 8, it is characterised in that: the degree of the white wine is 40-60 °, the amount of the white wine is that 5-7 times of medicinal material volume is measured, and the time of the immersion is 5-12 days.
10. a kind of Chinese materia medica preparation for treating osteopathy according to claim 1, it is characterised in that: the preservative is sorb Acid.
CN201811608637.3A 2018-12-27 2018-12-27 A kind of Chinese materia medica preparation and preparation method thereof for treating osteopathy Pending CN109620919A (en)

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