CN109620903A - A kind of health instant powder with improvement intestinal absorption ability - Google Patents
A kind of health instant powder with improvement intestinal absorption ability Download PDFInfo
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- CN109620903A CN109620903A CN201910115498.9A CN201910115498A CN109620903A CN 109620903 A CN109620903 A CN 109620903A CN 201910115498 A CN201910115498 A CN 201910115498A CN 109620903 A CN109620903 A CN 109620903A
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- instant powder
- intestinal absorption
- absorption ability
- health instant
- improving intestinal
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
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- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Epidemiology (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Immunology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
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- Food Science & Technology (AREA)
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- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Hawthorn, Poria cocos, Chinese yam are mainly contained with the health instant powder for improving intestinal absorption ability the present invention provides a kind of, is prepared with degreasing, enzyme process and fermentation multi-step Combined Treatment.There is the present invention health instant powder for improving intestinal absorption ability to adjust gastric acid secretion, protection stomach lining for that when improving intestinal absorption, can adjust the equilibrium between yin and yang between stomach, enhancing WeiDongLi Capsule.Experiments have shown that gastrointestinal function can be effectively improved, promote to digest and assimilate, realizes that lath increases the fat effect for increasing flesh.
Description
Technical field
The present invention relates to field of health care food, and in particular to a kind of with the health instant powder for improving intestinal absorption ability.
Background technique
Stomach is the most important digestive organs of our human bodies, it is responsible for the suction of the food digestion and nutriment of our bodies
It receives, functions of intestines and stomach once goes wrong, and will make food can not normal absorption and digestion.Food digestion is bad, can cause stomach
The problem of swollen, stomachache, even stomach film inflammation bleeding, can also cause hypoimmunity, lean body mass.
Entire digestive system including the vitals such as including gastrointestinal tract is known as " taste " by Chinese medicine.Chinese medicine thinks, taste
It is " the foundation of acquired constitution ".Record according to " Treatise on the spleen and stomach ": " disorder of the spleen and stomach caused by internal damage, all kinds of diseases and ailments are by giving birth to." " Synopsis Golden Chamber note " say: " blood of the vital organs of the human body,
Bad temper is had under one's command entirely." " Plain Questions focus the five internal organs generate a piece " described: " and The spleen has the function to transport and transform nutrients foodstuff essence, to give birth to and bring up muscle, thus it is main
Meat ".For the patient of the digestive problems such as deficiency-cold in spleen and stomach, weakness of the spleen and the stomach, the plain Sheng of stomach energy, mechanism of qi retardance, selective Chinese medicine type
It is more, but bitter, puckery, poor taste, consumer are often difficult to adhere to taking for a long time mostly, cause final therapeutic effect bad.
The present inventor is according to Chinese medicine theory selected Chinese medicinal material, using modern biotechnology extractive technique, extraction effectively at
Point, a kind of health instant powder has been made, good mouthfeel is easy to take, there is good improvement intestinal absorption effect, so as to complete
The present invention.
Summary of the invention
Based on this, the purpose of the present invention is to provide a kind of with the health instant powder for improving intestinal absorption ability.
A kind of health instant powder with improvement intestinal absorption ability, preparation method mainly include the following steps:
(1) by Poria cocos, hawthorn and Chinese yam ungrease treatment；
(2) step (1) degreasing product obtained is digested；
(3) it ferments to step (2) enzymolysis product obtained.
In wherein some embodiments, the preparation method of the health instant powder further includes step (4): step (3) is obtained
The tunning filtering obtained, obtains filtrate, is heated to 50-70 DEG C, and dextrin and white sugar, spray drying, gained particle is then added
As health instant powder.
In wherein some embodiments, Poria cocos, hawthorn and Chinese yam described in step (1) are described with poidometer after drying
The ratio between Poria cocos, hawthorn and the parts by weight of Chinese yam are as follows: (20-40): (30-40): (30-40).
The purpose of ungrease treatment described in step (1) is in advance to remove the liposoluble constituent in Poria cocos, hawthorn and Chinese yam
It removes.In wherein some embodiments, the degreasing specific steps can be with are as follows: mixes Poria cocos, hawthorn and Chinese yam, crushes, mistake
10-40 mesh obtains herb powder；Dehydrated alcohol is added into herb powder, the additive amount of the dehydrated alcohol is Chinese medicine
6-10 times of powder weight；Degreasing 24-48h is stirred under the conditions of 20-30 DEG C, is then filtered, is obtained filter residue；By filter residue-
It is freeze-dried under 0.2Mpa for 24 hours, obtains degreasing product.
Inventors have found that ungrease treatment has larger impact to the efficiency of subsequent enzymatic hydrolysis and fermentation, especially to the fermentation of acquisition
The yield of general flavone has larger impact in composition.It is the possible reason is parent after ungrease treatment, in Poria cocos, hawthorn and Chinese yam
Lipid substance is reduced, and avoids the inhibition that lipophilic substance grows subsequent enzyme digestion reaction and zymophyte；In addition, ungrease treatment
Facilitate disintegrating for plant cell membrane.
Enzymatic hydrolysis described in step (2) is to be digested using alpha-amylase, cellulase, to open plant cell wall, had
Conducive to the progress of subsequent fermentation.In wherein some embodiments, the step of the enzymatic hydrolysis are as follows: by degreasing product and water according to 1:15
Weight ratio mixing, amylase and cellulase is then added, wherein the alpha-amylase, the mass ratio of cellulase are
1:3 is always the 0.1-0.2% of degreasing products weight with enzyme amount；The condition of enzymatic hydrolysis are as follows: temperature is 35-55 DEG C, reaction time 6-
10 hours, pH value 6.5-7.0；Enzyme digestion reaction whole process is kept stirring state, and the speed of the stirring is 60-120rpm/min；
After enzyme digestion reaction, it is cooled to room temperature, enzyme deactivation sterilizing obtains enzymolysis product.
The fermentation of enzymolysis product described in step (3) is to be fermented using Bifidobacterium to enzymolysis product, to be had
There is the tunning of excellent flavor and healthcare function.In wherein some embodiments, the step of the fermentation are as follows: by enzymolysis product
It being placed in fermentor, inoculating bifidobacterium, then heats to 25-35 DEG C, ventilatory capacity ferments 2-3 days under conditions of being 1-4VVM,
Obtain tunning；Wherein, the inoculum concentration of the Bifidobacterium is (1 × 108-5×1010)CFU/ml.Fermentation whole process may be used also
To be stirred, mixing speed 30-60rpm/min.
In wherein some embodiments, the additional amount of step (4) described dextrin is the 0.03-0.05% of filtrate weight, institute
The additional amount for stating white sugar is the 0.03-0.1% of filtrate weight.
Being had by the health instant powder that above-mentioned preparation method obtains improves intestinal absorption ability.
In wherein some embodiments, in the health instant powder that is prepared, general flavone content 82.6-105.3mg/
100g." general flavone " of the present invention, " flavones ", " flavone compound " are identical with the meaning of " bioflavonoid ", are to have
Chromone ring and phenyl ring are the general name of a kind of compound of basic structure, belong to Secondary Metabolite Production in Plants, including flavones, class Huang
Ketone, isoflavones, chalcone etc..
The present invention has the advantage that and the utility model has the advantages that
1, the present invention has the health instant powder for improving intestinal absorption ability using hawthorn as monarch drug in a prescription, using Poria cocos as ministerial drug, with mountain
Medicine is adjuvant, adjusts the equilibrium between yin and yang between stomach, and enhancing WeiDongLi Capsule adjusts gastric acid secretion, protection stomach lining.Test table
Bright, gastrointestinal function can be effectively improved by taking electuary made from the present embodiment for a long time, promote to digest and assimilate, and realize that lath increases fat increasing
The effect of flesh.
2, final product can be greatly improved with degreasing, enzyme process and fermentation multi-step Combined Treatment in preparation process of the invention
The content of middle general flavone compares single method, more dominant on the composition of effect substance and content.
3, raw material sources of the invention are natural, and technique is environmentally protective, environmental-friendly.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below
Step ground detailed description, embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can refer to
Routine techniques carries out.
Agents useful for same in following embodiment is unless otherwise specified commercially available conventional common agents.
Experimental method used in following embodiment is unless otherwise specified the operating method of this field routine.
The measurement of general flavone content uses NaNO2-AlCl3Method measures (Gonzalez R, Ballester I, Lopez-
Posada R,et al.Effects of Flavonoids and other Polyphenols on Inflammation
[J].Critical Reviews In Food Science And Nutrition,2011,51(4):331-362.)。
Alpha-amylase according to the present invention has catalytic action to the hydrolysis of starch, and suitable alpha-amylase can be Shanghai
The alpha-amylase (hay bacillus) of Gu Chen Biotechnology Co., Ltd.
Cellulase according to the present invention has catalytic action to the hydrolysis of cellulose, and suitable cellulase can be
The cellulase (Trichoderma viride) of Hai Gu minister Biotechnology Co., Ltd.
Bifidobacterium according to the present invention can be Shaanxi Sai En Biotechnology Co., Ltd bifidobacterium bifidum or
It is the bifidobacterium infantis of Xi'an Jim Press bioengineering Co., Ltd.
Poria cocos according to the present invention is Chinese medicine, is the dry of Polyporaceae plant Poria cocos Poria cocos (Schw.) Wolf
Dry sclerotium.Application in TCM: it is sweet in flavor, light, it is mild-natured；Enter the heart, spleen, lung channel.Function: eliminating dampness and diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative.It is existing
In generation, research shows that Poria cocos has significant protective effect to mouse liver injury caused by carbon tetrachloride, can make gpt activity
It is substantially reduced, prevents necrosis of liver cells.Poria cocos preserved material has direct relexation to family's rabbits infestines, makes smooth muscle contraction amplitude
It reduces, tension decline has inhibiting effect to ulcer caused by rat pylorus ligation.And gastric secretion and free acid content can be reduced.
Hawthorn according to the present invention is Chinese medicine, is rosaceous plant hawthorn Crataegus pinnatifida
The fruit of Bge.Var.major N.E.Br. or fructus crataegi cuneatae Crataegus cuneata Sieb.Et Zucc..Application in TCM:
It is sour, sweet, slightly warm in nature；Enter spleen, stomach, Liver Channel.Function: digestion gathered food, scattered silt blood, expelling tenia.Modern research shows that after hawthorn is for oral administration
It can increase enzyme in stomach, promote digestion；Lipase contained therein can also promote the digestion of fatty dyspepsia.
Chinese yam according to the present invention is the stem tuber of Dioscoreaceae plant Chinese yam Dioscorea opposita Thunb..In
Medicine application: it is sweet in flavor, it is mild-natured；Enter lung, spleen, kidney channel.Function: invigorating the spleen tonifying lung, is reinforced the kidney, strengthening the essence.Modern research shows that Rhizoma Dioscoreae, clear
Four kinds of stir-baked RHIZOMA DIOSCOREAE, stir-baked RHIZOMA DIOSCOREAE with soil, Rhizoma Dioscoreae (parched with bran) Chinese yam product decoctions have obvious effect to family's rabbits infestines periodic activity.
Embodiment 1
A kind of health instant powder with improvement intestinal absorption ability, preparation method include the following steps:
(1) it by the Poria cocos of 20 parts by weight, the hawthorn of 40 parts by weight and 30 parts by weight Chinese yams, crushes, 40 meshes is crossed, using 6
Times mass parts dehydrated alcohol carries out degreasing 48h, and skimming temp is 20 DEG C, mixing speed 120rpm/min；After de-ester reaction, so
After filter, obtain filter residue；Filter residue is freeze-dried for 24 hours at -0.2Mpa, obtains degreasing product；
(2) it by step (1) 10 mass parts of degreasing dry powder obtained and 150 mass parts of water, is added in enzymatic hydrolysis kettle, adjusts pH
To 7.0；0.0025 mass parts alpha-amylase and 0.0075 parts by mass of cellulose enzyme is added, is reacted 10 hours at 35 DEG C, digests
Reaction is whole to keep 120rpm/min stirring, after enzyme digestion reaction, is cooled to room temperature, and 110 DEG C of enzyme deactivations sterilize 10min,
Obtain 143.6 mass parts enzymolysis products；
(3) the 100 mass parts enzymolysis products for obtaining step (2) are added in fermentor, and 0.005 mass parts glucose is added
With 0.1 mass parts urea, steam sterilizing 10min is carried out at 115 DEG C, is cooled to room temperature, is aseptically inoculated with not tally bifid
Bacillus, inoculum concentration are 1 × 108CFU/ml is warming up to 25 DEG C, is stirred with 60rpm/min, and ventilatory capacity ferments under conditions of being 1VVM
3 days, obtain tunning；
(4) tunning for obtaining step (3) filters, and obtains filtrate, is heated to 50 DEG C, and dextrin and white is then added
Sugar, spray drying, gained particle is health instant powder；Wherein the additional amount of dextrin is the 0.03% of filtrate weight, and white sugar is added
Amount is the 0.03% of filtrate weight.
Embodiment 2
A kind of health instant powder with improvement intestinal absorption ability, preparation method include the following steps:
(1) it by the Poria cocos of 40 parts by weight, the hawthorn of 30 parts by weight and 40 parts by weight Chinese yams, crushes, 10 meshes is crossed, using 10
Times mass parts dehydrated alcohol carries out degreasing for 24 hours, and skimming temp is 30 DEG C, mixing speed 60rpm/min；After de-ester reaction, so
After filter, obtain filter residue；Filter residue is freeze-dried for 24 hours at -0.2Mpa, obtains degreasing product；
(2) it by step (1) 10 mass parts of degreasing dry powder obtained and 150 mass parts of water, is added in enzymatic hydrolysis kettle, adjusts pH
To 6.5；0.005 mass parts alpha-amylase and 0.015 parts by mass of cellulose enzyme is added, is reacted 6 hours at 55 DEG C；Enzyme digestion reaction
Whole process keeps 60rpm/min stirring, after enzyme digestion reaction, is cooled to room temperature, and 110 DEG C of enzyme deactivations sterilize 10min, obtains
143.1 mass parts enzymolysis products；
(3) the 100 mass parts enzymolysis products for obtaining step (2) are added in fermentor, and 0.01 mass parts glucose is added
With 0.2 mass parts urea, steam sterilizing 10min is carried out at 115 DEG C, is cooled to room temperature, is aseptically inoculated with not tally bifid
Bacillus, inoculum concentration are 5 × 1010CFU/ml is warming up to 40 DEG C, is stirred with 30rpm/min, and ventilatory capacity ferments under conditions of being 4VVM
2 days, obtain tunning；
(4) tunning for obtaining step (3) filters, and obtains filtrate, is heated to 70 DEG C, and dextrin and white is then added
Sugar, spray drying, gained particle is health instant powder；Wherein the additional amount of dextrin is the 0.05% of filtrate weight, and white sugar is added
Amount is the 0.1% of filtrate weight.
Embodiment 3
A kind of health instant powder with improvement intestinal absorption ability, preparation method include the following steps:
(1) it by the Poria cocos of 30 parts by weight, the hawthorn of 35 parts by weight and 35 parts by weight Chinese yams, crushes, 20 meshes is crossed, using 8
Times mass parts dehydrated alcohol carries out degreasing 36h, and skimming temp is 25 DEG C, mixing speed 80rpm/min；After de-ester reaction, so
After filter, obtain filter residue；Filter residue is freeze-dried for 24 hours at -0.2Mpa, obtains degreasing product；
(2) it by step (1) 10 mass parts of degreasing dry powder obtained and 150 mass parts of water, is added in enzymatic hydrolysis kettle, adjusts pH
To 6.8；0.004 mass parts alpha-amylase and 0.012 parts by mass of cellulose enzyme is added, is reacted 8 hours at 45 DEG C；Enzyme digestion reaction
Whole process keeps 90rpm/min stirring, after enzyme digestion reaction, is cooled to room temperature, and 110 DEG C of enzyme deactivations sterilize 10min, obtains
142.6 mass parts enzymolysis products；
(3) the 100 mass parts enzymolysis products for obtaining step (2) are added in fermentor, and 0.0075 mass parts grape is added
Sugar and 0.15 mass parts urea carry out steam sterilizing 10min at 115 DEG C, are cooled to room temperature, and it is double to be aseptically inoculated with baby
Discrimination bacillus, inoculum concentration are 1 × 109CFU/ml is warming up to 30 DEG C, is stirred with 45rpm/min, and ventilatory capacity is sent out under conditions of being 3VVM
Ferment 2 days, obtain tunning；
(4) tunning for obtaining step (3) filters, and obtains filtrate, is heated to 60 DEG C, and dextrin and white is then added
Sugar, spray drying, gained particle is health instant powder；Wherein the additional amount of dextrin is the 0.04% of filtrate weight, and white sugar is added
Amount is the 0.06% of filtrate weight.
Comparative example 1
Without defatting step, remaining step and condition are same as Example 3.
Comparative example 2
Without enzymolysis step, remaining step and condition are same as Example 3.
Comparative example 3
Without fermentation step, remaining step and condition are same as Example 3.
Test the measurement of 1 general flavone
To health instant powder made from embodiment 1-3 and comparative example 1-3, it is diluted to 20 times of aqueous solution, sequentially determining is always yellow
Ketone content.The results are shown in Table 1.
1 Determination of Total Flavonoids result record sheet of table
| Project | General flavone content (mg/100g sample) |
| Embodiment 1 | 82.6 |
| Embodiment 2 | 92.4 |
| Embodiment 3 | 105.3 |
| Comparative example 1 | 42.5 |
| Comparative example 2 | 52.3 |
| Comparative example 3 | 29.5 |
From the data in table 1, it can be seen that the health instant powder obtained using preparation method of the present invention, with degreasing, enzyme process and fermentation multistep
The content of general flavone in final tunning can be greatly improved in rapid Combined Treatment, compare single method, in the group of effect substance
At with it is more dominant in content.
Test 2 volunteers test
It inquires into health instant powder of the present invention and improves application effect in stomach malabsorption crowd.
Method: the volunteer of stomach malabsorption, body mass index (BMI) < 18.5kg/m are chosen2, generally partially thin, will
Hope person totally 120, wherein male 76, female 44, the age 25-55 years old, the median age 38 years old, Symptoms were to show thin, abdominal distension, abdomen
Rush down, the volunteer of sallow complexion, hypoimmunity is research object, height, weight and nutritionally relevant inspection are collected when physical examination and is referred to
Data such as (hemoglobin, albumin, prealbumin, transferrins) are marked, health instant powder of the present invention is given and comparative example 1-3 is made
Sample carry out oral conditioning, and follow-up half a year, compare related nutritional index variation (each group takes its average value) situation.It is all
Volunteer is divided into 6 groups at random, every group of 20 people.It takes as once in the morning and once at night, every time a pouch, every bag is 10 grams, and boiled water is taken after mixing it with water.
It is carried out follow-up 6 months after experiment, and checks index of correlation, further Comparative nutrition index situation of change, observation is originally
Invention health instant powder improves the effect of intestinal absorption in stomach malabsorption volunteer crowd, and the results are shown in Table 2.
Table 2 takes index of correlation situation of change before and after 6 months health instant powders
As shown in Table 2, after volunteer takes health instant powder, BMI, hemoglobin, albumin, prealbumin, transferrins
Equal nutritive indexes significantly improve, and illustrate that intestinal absorption ability can be obviously improved by taking health instant powder, promote effective nutrition at
Part being absorbed and utilized in human body.
By embodiment 1-3 and comparative example 1-3 comparison it is found that health instant powder embodiment 1-3 of the present invention has better curative effect,
The either nutritive indexes such as body mass index BMI or hemoglobin, albumen, prealbumin, transferrins have preferably
It is promoted, realizes that lath increases the fat effect for increasing flesh, improve the immunity of the human body.
Further volunteer's progress to using 1-3 of the embodiment of the present invention that there is the health instant powder for improving intestinal absorption ability
Physical examination discovery, after health instant powder half a year of the present invention, volunteer's WeiDongLi Capsule increases, and digestion power enhancing has excessive gastric acid point
The volunteer's gastric acid secretion secreted significantly reduces, stomach lining and ordinary person are no different；It is low to show thin, abdominal distension, diarrhea, sallow complexion, immunity
Under symptom make moderate progress.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore
All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, all of which are still within the scope of the technical scheme of the invention.
Claims (9)
1. a kind of with the health instant powder for improving intestinal absorption ability, which is characterized in that preparation method mainly includes walking as follows
It is rapid:
(1) by Poria cocos, hawthorn and Chinese yam ungrease treatment；
(2) step (1) degreasing product obtained is digested；
(3) it ferments to step (2) enzymolysis product obtained.
2. according to claim 1 have the health instant powder for improving intestinal absorption ability, which is characterized in that the health care
The preparation method of electuary further includes step (4): the tunning that step (3) are obtained filters, and obtains filtrate, is heated to 50-70
DEG C, dextrin and white sugar is then added, spray drying, gained particle is health instant powder.
3. according to claim 1 have the health instant powder for improving intestinal absorption ability, which is characterized in that in step (1)
Poria cocos, hawthorn and the Chinese yam, with poidometer after drying, the ratio between the Poria cocos, hawthorn and parts by weight of Chinese yam are as follows:
(20-40):(30-40):(30-40)。
4. according to claim 3 have the health instant powder for improving intestinal absorption ability, which is characterized in that the degreasing
Specific steps are as follows: Poria cocos, hawthorn and Chinese yam are mixed, crushed, 10-40 mesh is crossed, obtains herb powder；Add into herb powder
Enter dehydrated alcohol, the additive amount of the dehydrated alcohol is 6-10 times of herb powder weight；It is stirred under the conditions of 20-30 DEG C de-
Rouge 24-48h, is then filtered, and obtains filter residue；Filter residue is freeze-dried for 24 hours at -0.2Mpa, obtains degreasing product.
5. according to claim 1 have the health instant powder for improving intestinal absorption ability, which is characterized in that step (2) institute
The enzymatic hydrolysis stated is digested using alpha-amylase, cellulase.
6. according to claim 5 have the health instant powder for improving intestinal absorption ability, which is characterized in that the enzymatic hydrolysis
Step are as follows: degreasing product and water are mixed according to the weight ratio of 1:15, amylase and cellulase is then added, wherein described
Alpha-amylase, the mass ratio of cellulase are 1:3, are always the 0.1-0.2% of degreasing products weight with enzyme amount；The condition of enzymatic hydrolysis
Are as follows: temperature is 35-55 DEG C, and the reaction time is 6-10 hours, pH value 6.5-7.0；Enzyme digestion reaction whole process is kept stirring state, institute
The speed for stating stirring is 60-120rpm/min；After enzyme digestion reaction, it is cooled to room temperature, enzyme deactivation sterilizing obtains enzymolysis product.
7. according to claim 1 have the health instant powder for improving intestinal absorption ability, which is characterized in that step (3) institute
The fermentation for the enzymolysis product stated ferments to enzymolysis product using Bifidobacterium.
8. according to claim 7 have the health instant powder for improving intestinal absorption ability, which is characterized in that the fermentation
Step are as follows: enzymolysis product is placed in fermentor, inoculating bifidobacterium, then heats to 25-35 DEG C, ventilatory capacity is 1-4VVM's
Under the conditions of ferment 2-3 days, obtain tunning；Wherein, the inoculum concentration of the Bifidobacterium is (1 × 108-5×1010)CFU/
Ml, fermentation whole process are also stirred, mixing speed 30-60rpm/min.
9. according to claim 2 have the health instant powder for improving intestinal absorption ability, which is characterized in that by step (3)
The tunning of acquisition filters, and obtains filtrate, is heated to 50-70 DEG C, and dextrin and white sugar, spray drying, gained is then added
Grain is health instant powder；Wherein the additional amount of dextrin is the 0.03-0.05% of filtrate weight, and white sugar additional amount is filtrate weight
0.03-0.1%。
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| CN110075203A (en) * | 2019-05-30 | 2019-08-02 | 周国洪 | A kind of composition of coordinating intestines and stomach, reinforcing spleen to promote digestion, prevention and treatment aphtha and constipation repeatedly |
| CN113812550A (en) * | 2021-08-27 | 2021-12-21 | 上海凯宝健康科技有限公司 | Ginseng and poria cocos solid beverage and preparation method thereof |
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Application publication date: 20190416 |
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