CN109620768A - Polypeptide targets factor coniplexes - Google Patents
Polypeptide targets factor coniplexes Download PDFInfo
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- CN109620768A CN109620768A CN201811378022.6A CN201811378022A CN109620768A CN 109620768 A CN109620768 A CN 109620768A CN 201811378022 A CN201811378022 A CN 201811378022A CN 109620768 A CN109620768 A CN 109620768A
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- parts
- polypeptide
- coniplexes
- factor
- targets
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The present invention provides a kind of polypeptides to target factor coniplexes, and the polypeptide targeting factor coniplexes include following components in parts by weight: 1-3 parts of polypeptide targeting factor, 15-25 parts of polysaccharide, 8-15 parts of extract, 3-8 parts of pepper element, 2-5 parts of wintergreen, 0.5-1 parts of active carbon, 45-55 parts of distilled water.The present invention provides a kind of polypeptide targeting factor coniplexes and mixes at a specific ratio using polypeptide as raw materials such as targeting factors and polysaccharide, to body with good health-care effect.
Description
Technical field
The present invention relates to biological health fields more particularly to a kind of polypeptide to target factor coniplexes.
Background technique
With the development of society, more and more people start to pay attention to the health care of chest, lymph and body other organs
Get up.People would generally wipe some body lotions, play some health-care effects, but many body lotion addition on the market at present
Some additives being harmful to the human body, for a long time using harmful to health.In addition, the body lotion of the prior art is applied on skin,
It can stop the pore of skin, so that skin inside and air insulated, to be easy to cause the symptoms such as allergy.
The many active materials of human body be all in the form of peptide existing for.Peptide be related to human body hormone, nerve, cell growth and
Each field of reproduction, importance are to adjust the physiological function of each system and cell in vivo, activate related enzyme system in vivo, promote
The permeability of intermediate supersession film has the function of that targeting penetrates.
Polysaccharide be it is a kind of as different sugar units by natural polymer made of glucosides key connection, it universally present in from
It is safe and non-toxic in right boundary, there is extraordinary biocompatibility and biological degradability.
It is retrieved according to related data of the inventor to this field, there is presently no discoveries to be applied to body for polypeptide and polysaccharide
The relevant report of cream.
Summary of the invention
The main purpose of the present invention is to provide a kind of polypeptides to target factor coniplexes, using polypeptide as targeting factor, with
And the raw materials such as polysaccharide, it mixes at a specific ratio, there is good health-care effect to body.
In order to achieve the above objectives, the technical scheme of the present invention is realized as follows:
An aspect of of the present present invention provides a kind of polypeptide targeting factor coniplexes, and the polypeptide targeting factor coniplexes include following heavy
Measure the component of part: 1-3 parts of polypeptide targeting factor, 15-25 parts of polysaccharide, 8-15 parts of extract, 3-8 parts of pepper element, wintergreen 2-5
Part, 0.5-1 parts of active carbon, 45-55 parts of distilled water.
It preferably, further include 2-5 parts of glycerol.
Preferably, the polypeptide targeting factor are as follows: arginine-glycine-aspartic acid polypeptide.
Preferably, the polysaccharide includes: 5-10 parts of chitosan, 5-8 parts of glucose, 5-7 parts of fructose.
Preferably, the extract includes: 3-5 parts of oil of ginger, 2-5 parts of Flos Carthami extract, 3-5 parts of safflower essential oil.
Preferably, the polypeptide targeting factor coniplexes application field includes: face frost, body lotion.
Preferably, polypeptide targeting factor coniplexes include following components in parts by weight: 2 parts of polypeptide targeting factor, more
20 parts of sugar, 12 parts of extract, pepper plain 5 parts, 3 parts of wintergreen, 0.8 part of active carbon, 50 parts of distilled water.
Preferably, the preparation method of the polypeptide targeting factor coniplexes, includes the following steps:
Step 1: it extracts: fresh ginger is extracted, ginger liquid is removed, oil of ginger is made;Safflower is extracted, obtain Flos Carthami extract
With safflower essential oil;
Step 2: mixing: by 1-3 parts of polypeptide targeting factor, 15-25 parts of polysaccharide, 8-15 parts of extract, 3-8 parts of pepper element, Chinese ilex
Oily 2-5 parts of mixing, stirs evenly, and using pulverizer, is added distilled water 45-55 parts, is stirred for uniformly, obtaining polypeptide targeting factor
Mixture;
Step 3: charing process: being added active carbon 0.5-1 parts in the polypeptide targeting factor cocktails described in step 2, stirring is equal
It is even, it obtains becoming product;
Step 4: heating: semi-finished product described in step 3 are heated, and temperature setting is 50~55 DEG C, heating time 30-60min,
The polypeptide targeting factor coniplexes are made.
Preferably, the polypeptide targeting factor coniplexes are paste.
Preferably, the active carbon is powdered, and granularity is 800-1000 mesh.
Beneficial effects of the present invention:
1. the present invention provides a kind of polypeptide targeting factor coniplexes, using polypeptide as raw materials such as targeting factors and polysaccharide, with spy
Fixed ratio mixing, has good health-care effect to body.
2. present invention could apply to body lotion, face frost can also be applied to, can be directly applied on skin, to human body without
Side effect.It should be understood that menstrual woman and the pregnancy women disabling present invention.
3. the present invention, as polypeptide targeting factor, has targeting well using arginine-glycine-aspartic acid polypeptide
Function is penetrated, skin can be promoted to absorb inside rapid osmotic to skin.
4, the present invention can be promoted blood circulation using pepper element, play the role of activating microcirculation and removing stasis medicinal.Oil of ginger and wintergreen
Mutually collaboration, can generate heat, dissipation stagnation resolvation, stimulation cycle, oily dissipating bind knot effect, Flos Carthami extract and safflower essential oil are mutually assisted
Together, thrombus can be alleviated, improve microcirculation, have dredgingization mass-dissipating efficacy to mammary gland.
5, present invention addition active carbon enables to polypeptide targeting factor coniplexes product of the invention loose porous, applies
After skin, so that coming into full contact with inside skin with air, allergy can be prevented, human body relaxes to avoid the pore for stopping skin
It is moderately high.And granularity of activated carbon of the present invention is 800-1000 mesh, it is very thin, it can promote and polypeptide targeting factor of the present invention
With merging for polysaccharide, it can be blended in one completely.
6. the present invention can speed up hydrolysis, obtained polypeptide target rapidly using three kinds of chitosan, glucose, fructose sugar mixing
To factor cocktails, and then polypeptide targeting factor coniplexes are obtained, improves industrial production efficiency.
Specific embodiment
Technical solution of the present invention is clearly and completely described combined with specific embodiments below, it is to be understood that under
Described embodiments are only a part of the embodiments of the present invention in face, instead of all the embodiments.
Embodiment one
The embodiment of the present invention one provides a kind of polypeptide targeting factor coniplexes, including following components in parts by weight: polypeptide targeting
Factor 1kg, polysaccharide 15kg, extract 8kg, pepper element 3kg, wintergreen 2kg, active carbon 0.5kg, distilled water 45L, glycerol 2kg.
The polypeptide targeting factor are as follows: arginine-glycine-aspartic acid polypeptide.
The polysaccharide includes: chitosan 5kg, glucose 5kg, fructose 5kg.
The extract includes: oil of ginger 3kg, Flos Carthami extract 2kg, safflower essential oil 3kg.
The polypeptide targeting factor coniplexes application field includes: face frost, body lotion.
The preparation method of the embodiment of the present invention one, includes the following steps:
Step 1: it extracts: fresh ginger is extracted, ginger liquid is removed, oil of ginger is made;Safflower is extracted, obtain Flos Carthami extract
With safflower essential oil;
Step 2: mixing: by polypeptide targeting factor 1kg, polysaccharide 15kg, extract 8kg, pepper element 3kg, wintergreen 2kg, glycerol
2kg mixing, stirs evenly, and using pulverizer, distilled water 45L is added, and is stirred for uniformly, obtaining polypeptide targeting factor cocktails;
Step 3: charing process: being added active carbon 0.5kg in the polypeptide targeting factor cocktails described in step 2, stir evenly,
It obtains becoming product;
Step 4: heating: semi-finished product described in step 3 are heated, and temperature setting is 50 DEG C, heating time 30min, and cream is made
The polypeptide of shape targets factor coniplexes.
Embodiment two
The embodiment of the present invention two provides a kind of polypeptide targeting factor coniplexes, including following components in parts by weight: polypeptide targeting
Factor 3kg, polysaccharide 25kg, extract 15kg, pepper element 8kg, wintergreen 5kg, active carbon 1kg, distilled water 55L, glycerol 5kg.
The polypeptide targeting factor are as follows: arginine-glycine-aspartic acid polypeptide.
The polysaccharide includes: chitosan 10kg, glucose 8kg, fructose 7kg.
The extract includes: oil of ginger 5kg, Flos Carthami extract 5kg, safflower essential oil 5kg.
The polypeptide targeting factor coniplexes application field includes: face frost, body lotion.
The preparation method of the embodiment of the present invention two, includes the following steps:
Step 1: it extracts: fresh ginger is extracted, ginger liquid is removed, oil of ginger is made;Safflower is extracted, obtain Flos Carthami extract
With safflower essential oil;
Step 2: mixing: by polypeptide targeting factor 3kg, polysaccharide 25kg, extract 15kg, pepper element 8kg, wintergreen 5kg, glycerol
5kg mixing, stirs evenly, and using pulverizer, distilled water 55L is added, and is stirred for uniformly, obtaining polypeptide targeting factor cocktails;
Step 3: charing process: active carbon 1kg is added in the polypeptide targeting factor cocktails described in step 2, stirs evenly, obtains
To becoming product;
Step 4: heating: semi-finished product described in step 3 are heated, and temperature setting is 55 DEG C, heating time 60min, and cream is made
The polypeptide of shape targets factor coniplexes.
Embodiment three
The embodiment of the present invention three provides a kind of polypeptide targeting factor coniplexes, comprising: polypeptide targeting factor 2kg, polysaccharide 20kg,
Extract 12kg, pepper element 5kg, wintergreen 3kg, active carbon 0.8kg, distilled water 50L.
The polypeptide targeting factor are as follows: arginine-glycine-aspartic acid polypeptide.
The polysaccharide includes: chitosan 8kg, glucose 6kg, fructose 6kg.
The extract includes: oil of ginger 4kg, Flos Carthami extract 4kg, safflower essential oil 4kg.
The polypeptide targeting factor coniplexes application field includes: face frost, body lotion.
The preparation method of the embodiment of the present invention three, includes the following steps:
Step 1: it extracts: fresh ginger is extracted, ginger liquid is removed, oil of ginger is made;Safflower is extracted, obtain Flos Carthami extract
With safflower essential oil;
Step 2: mixing: polypeptide targeting factor 2kg, polysaccharide 20kg, extract 12kg, pepper element 5kg, wintergreen 3kg are mixed,
It stirs evenly, using pulverizer, distilled water 5L is added, be stirred for uniformly, obtaining polypeptide targeting factor cocktails;
Step 3: charing process: being added active carbon 0.8kg in the polypeptide targeting factor cocktails described in step 2, stir evenly,
It obtains becoming product;
Step 4: heating: semi-finished product described in step 3 are heated, and temperature setting is 52 DEG C, heating time 45min, and cream is made
The polypeptide of shape targets factor coniplexes.
It should be understood that active carbon used in the embodiment of the present invention be it is powdered, granularity be 800-1000 mesh.
By experimental analysis and comparison, polypeptide targeting factor coniplexes of the invention are put into effect test examination, it will be of the invention
Polypeptide targets factor coniplexes as body lotion and wipes body, and 20 people's tests, 19 people have is good for chest effect well, and only 1
It is a invalid.
The above description is merely a specific embodiment, but simultaneously difference is limited to this to protection scope of the present invention, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of polypeptide targets factor coniplexes, which is characterized in that the polypeptide targeting factor coniplexes include following weight parts
Component: it is 1-3 parts of polypeptide targeting factor, 15-25 parts of polysaccharide, 8-15 parts of extract, 3-8 parts of pepper element, 2-5 parts of wintergreen, living
Property 0.5-1 parts of charcoal, 45-55 parts of distilled water.
2. polypeptide according to claim 1 targets factor coniplexes, which is characterized in that further include 2-5 parts of glycerol.
3. polypeptide according to claim 1 targets factor coniplexes, which is characterized in that the polypeptide targeting factor are as follows: essence
Propylhomoserin-Gly-Asp polypeptide.
4. polypeptide according to claim 1 targets factor coniplexes, which is characterized in that the polysaccharide includes: chitosan 5-
10 parts, 5-8 parts of glucose, 5-7 parts of fructose.
5. polypeptide according to claim 1 targets factor coniplexes, which is characterized in that the extract includes: oil of ginger
3-5 parts, 2-5 parts of Flos Carthami extract, 3-5 parts of safflower essential oil.
6. polypeptide according to claim 1 targets factor coniplexes, which is characterized in that the polypeptide targets factor coniplexes
Application field includes: face frost, body lotion.
7. polypeptide according to claim 1 targets factor coniplexes, which is characterized in that the polypeptide targets factor coniplexes
Including following components in parts by weight: 2 parts of polypeptide targeting factor, 20 parts of polysaccharide, 12 parts of extract, pepper element 5 parts, 3 parts of wintergreen,
0.8 part of active carbon, 50 parts of distilled water.
8. polypeptide according to claim 1 targets factor coniplexes, which is characterized in that the polypeptide targets factor coniplexes
Preparation method, include the following steps:
Step 1: it extracts: fresh ginger is extracted, ginger liquid is removed, oil of ginger is made;Safflower is extracted, obtain Flos Carthami extract
With safflower essential oil;
Step 2: mixing: by 1-3 parts of polypeptide targeting factor, 15-25 parts of polysaccharide, 8-15 parts of extract, 3-8 parts of pepper element, Chinese ilex
Oily 2-5 parts of mixing, stirs evenly, and using pulverizer, is added distilled water 45-55 parts, is stirred for uniformly, obtaining polypeptide targeting factor
Mixture;
Step 3: charing process: being added active carbon 0.5-1 parts in the polypeptide targeting factor cocktails described in step 2, stirring is equal
It is even, it obtains becoming product;
Step 4: heating: semi-finished product described in step 3 are heated, and temperature setting is 50~55 DEG C, heating time 30-60min,
The polypeptide targeting factor coniplexes are made.
9. polypeptide according to claim 8 targets factor coniplexes, which is characterized in that the polypeptide targets factor coniplexes
For paste.
10. polypeptide according to claim 8 targets factor coniplexes, which is characterized in that the active carbon be it is powdered,
Granularity is 800-1000 mesh.
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CN201811378022.6A CN109620768A (en) | 2018-11-19 | 2018-11-19 | Polypeptide targets factor coniplexes |
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