CN110170040A - Improve the stifled injection and preparation method thereof of the lymph stasis of blood - Google Patents

Improve the stifled injection and preparation method thereof of the lymph stasis of blood Download PDF

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CN110170040A
CN110170040A CN201910194581.XA CN201910194581A CN110170040A CN 110170040 A CN110170040 A CN 110170040A CN 201910194581 A CN201910194581 A CN 201910194581A CN 110170040 A CN110170040 A CN 110170040A
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injection
blood
stifled
lymph
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崔海茹
崔海勇
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Shanghai Oubang Medical Management Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61K38/00Medicinal preparations containing peptides
    • A61K38/01Hydrolysed proteins; Derivatives thereof
    • A61K38/012Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/014Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00Drugs for disorders of the nervous system
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
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Abstract

This application discloses a kind of injections and preparation method thereof that the improvement lymph stasis of blood is stifled.The injection includes following weight parts raw material: 1-2 parts of collagen, 2-4 parts of Radix Astragali, and 2-4 parts and 100-200 parts physiological saline of Radix Angelicae Sinensis.Present application addresses lack how to increase qi-blood circulating, dredging the channel and lymph, exclude the injection for the toxin that the stasis of blood is blocked up.It by the injection in the application, dredges channels and collaterals, fill blood, mitigate the five internal organs burden, reach coordinating yin and yang balance, mould the effect of perfect figure.

Description

Improve the stifled injection and preparation method thereof of the lymph stasis of blood
Technical field
This application involves beautifying technique fields, in particular to a kind of injection and its preparation that the improvement lymph stasis of blood is stifled Method.
Background technique
Lymphatic system is defense function system important in human body, and everywhere throughout whole body, whole body has 7,800 lymph nodes. Lymphatic system, one side draining lymph liquid, the intracorporal foreign matter of removing machine, bacterium etc..Another aspect lymphatic system is body defenses Outpost, be scattered in body parts lymph node like a filter device, can effectively prevent the microorganism entered through lymphatic vessel.It is more next " toxin " that more people is concerned about is the main source of harm health, and lymphatic system is responsible for the important angle of human detoxification Color.
For about 10,000,000,000 lymphocytes in activity, lymphocyte is divided into T lymphocyte and B leaching in one healthy human body Bar cell.Both from marrow, but T cell is formed in thymus gland, its major function is the external invader of phagocytosis.B cell Most important function is the various antibody of production, just as the weapon inside troop, so that let us resists external invasion Object.The toxin expelling cell surface that Lymphatic Circulation makes toxin have sufficient chance powerful with human body contacts.Solvable removing toxic substances more than 99% Waste after element and metabolism can be removed by lymphatic system.If accumulation toxin is pathogenic root, toxin expelling construction It is exactly the starting point of health.The lymphatic system of human body is very huge, wherein can most react health is shoulder neck lymph, oxter leaching Bar and inguinal lymph.
Common people are after 30 years old, and no matter men and women is easy to put on weight, that is, figure is got fat, and middle aged posture occur.Mainly The reason is that caused by microcirculation is slack-off, the lymph stasis of blood is stifled, channels and collaterals are unsmooth.Examining can find that the stifled position got fat of these stasis of bloods is all being drenched Around fawning on.
How to increase qi-blood circulating, dredging the channel and lymph for lacking in the related technology, excludes the note of the stifled toxin of the stasis of blood The problem of penetrating liquid, currently no effective solution has been proposed.
Summary of the invention
The main purpose of the application is to provide a kind of injection and preparation method thereof that the improvement lymph stasis of blood is stifled, to solve such as The problem of what increases qi-blood circulating, dredging the channel and lymph, excludes the injection of the stifled toxin of the stasis of blood.
To achieve the goals above, according to the one aspect of the application, a kind of injection that the kind lymph stasis of blood is stifled is provided.
Improve the stifled injection of the lymph stasis of blood, including following weight parts raw material according to the application: 1-2 parts of collagen, yellow 2-4 parts of stilbene, 2-4 parts and 100-200 parts physiological saline of Radix Angelicae Sinensis.
Collagen increases the degree of packing and elasticity of skin, tensioning the skin.Collagen is boiomacromolecule, animal knot The main component in tissue is formed, and the functional protein that content is most in the mammalian body, distribution is most wide, accounts for total protein 25%~30%, certain organisms are even as high as 80% or more.
The acquisition methods of collagen can use, and cleaned with hot-water soak and smashed animal cartilage tissue;It is high Warm aging: the animal cartilage group after degreasing is woven in 70-90 DEG C of heat preservation 1-2 hours;Enzymatic hydrolysis: it is obtained after removing high temperature ageing Upper layer aqueous solution the enzyme that optimal pH is 7-9 is added into lower layer's mixture, in hydrolysis 2-5 hours of 40-68 DEG C of temperature, under described The weight ratio of layer mixture and the enzyme is 1:0.01-0.1;Removal of impurities: make the product obtained after enzymatic hydrolysis and atlapulgite or work Property carclazyte is contacted with the mixture of flocculant.
Radix Angelicae Sinensis can accelerate blood and Lymphatic Circulation with replenishing and activating blood, and it is stifled quickly to exclude toxin, the removing stasis of blood.It dredges channels and collaterals, mend Qi and blood mitigates the five internal organs burden, reaches coordinating yin and yang balance, moulds the effect of perfect figure.
Radix Astragali, can be with invigorating qi for strengthening superficies, pus draining and toxin expelling, diuresis, myogenic.For deficiency of vital energy and acking in strength, rush down prolapse of the anus for a long time, spontaneous perspiration, oedema, The long disunion of sub-official prolapses, chronic rephrilis protinuria, diabetes, the open sore part.
Further, Radix Angelicae Sinensis injection is made in the Radix Angelicae Sinensis.
Further, astragalus injection is made in the Radix Astragali.
Further, collagenocyte stoste is made in the collagen.
Further, stifled for the inguinal lymph stasis of blood.
Further, stifled for the shoulder neck lymph stasis of blood.
Further, stifled for the axillary lymph stasis of blood.
Specifically, inguinal lymph is the maximum toxin expelling system of entire reproductive system, when inguinal lymph blocks, It is stroked with hand, inside may feel that pain and butt crack tubercle, and walk or legs and feet are easy to feel like jelly when stair climbing, may also lead to Kidney deficiency.
It is blocked up by the way that the stifled injection of the improvement lymph stasis of blood is used for the inguinal lymph stasis of blood, is conducive to following at least one effect:
It is metabolized garbage toxins in pelvic cavity;
Improve renal function, female reproductive health;
It is fat to improve lower limb;
Improve hysteromyoma of gynecology, ovarian cyst;
Promote hormone, improves love life;
Palace of the Qing Dynasty blood, expelling of noxious substance in womb improve gynaecological imflammation;
It is ice-cold to improve trick;
Improve lower limb circulation, groin enlargement;
Improve lower limb numbness.
Further, it is stifled for the shoulder neck lymph stasis of blood to improve the stifled injection of the lymph stasis of blood.
Specifically, shoulder neck lymph is connected with artery, cervical vertebra, shoulder neck, clavicle, axillary lymph and head, just as the ten of human body Word crossing is the main thoroughfare on qi and blood supply head.Shoulder neck lymph is serious unsmooth, will lead to the blocking of shoulder neck and " wealth and rank packet " Generation.
It is blocked up by the way that the stifled injection of the improvement lymph stasis of blood is used for the shoulder neck lymph stasis of blood, is conducive to following at least one effect:
Improve sleep, dizziness headache, the dark yellow tarnish of blee;
Improve scapulohumeral periarthritis, shoulder neck pain, easy stiff neck, the symptom of failure of memory;
Improve brain Cycle Difference, blood supply insufficiency, the insufficient symptom of oxygen supply;
Improve the symptom of cervical lymph node enlargement, long acne;
Improve melanin easily precipitate, the symptom of easy long spot;
Prevent senile dementia and some cardio-cerebral diseases;
Improve abscess of throat;
Improve double chin, is conducive to lower jaw plastotype.
Further, it is stifled for the axillary lymph stasis of blood to improve the stifled injection of the lymph stasis of blood.
Specifically, axillary lymph and chest, arm and channels and collaterals, shoulder neck are closely connected.
It is stifled for the axillary lymph stasis of blood by improving the stifled injection of the lymph stasis of blood, be conducive to following at least one effect:
Improve chest pain with distension sensation, promotes body metabolism, toxin expelling;
Prevent thoracopathy;
Improve secondary cream, large arm is fat, relaxes;
It is metabolized the garbage toxins of chest;
Reduce oxter degras, exhaust gas;
Strengthen immunity enhances heart blood supply function.
To achieve the goals above, according to the another aspect of the application, a kind of side for preparing the injection is provided Method.
Include: according to the preparation method of the application
(1) traditional Chinese medicinal material raw materials are cleaned, drying;(2) it just crushes, is sieved;(3) it crushes, is sieved again;(4) with ultra-fine lamination ball Grinding machine is handled;(5) drug extract is obtained by extraction;(6) ultrasonic cut;(7) collagen is dissolved in deionized water and is made Injection is prepared at collagen aqueous solution and physiological saline mixing.
Further, medicinal material moisture content≤5% after step (1) drying;Step (2) the drug coarse powder passes through 200 Mesh;Step (3) medicinal powder passes through 800-1000 mesh;Step (4) the processing time is 5-10min;The step (5) Supercritical fluid extraction instrument is selected to be extracted, the supercritical fluid flow velocity of extraction kettle is 35-45L/h, and temperature is 25-40 DEG C, Pressure is 35-46MPa, extraction time 5-6h;Step (6) ultrasonic frequency is 70-130KHZ.
The application can dredge channels and collaterals, fill blood, and mitigate the five internal organs burden, reach coordinating yin and yang balance, mould the effect of perfect figure Fruit.According to the stifled degree of the aging at shoulder neck and back and the lymph stasis of blood, is operated according to certain course for the treatment of, the health at back can be passed through The total health for promoting body slows down headache, fatiguability, symptoms, the pine of back skin surface such as shoulder neck acid is swollen, trick is ice-cold Relaxation, too fat to move, lower extension shape chevron etc. can also obtain a degree of improvement.Abdomen and the dredging of the lymph of leg, can improve leg It is portion's oedema, thick swollen, prevent varication.
Specific embodiment
It is right below in conjunction with the embodiment of the present application in order to make those skilled in the art more fully understand application scheme Technical solution in the embodiment of the present application is clearly and completely described, it is clear that described embodiment is only the application one Partial embodiment, instead of all the embodiments.Based on the embodiment in the application, those of ordinary skill in the art are not having Every other embodiment obtained under the premise of creative work is made, shall fall within the protection scope of the present application.
Embodiment 1
Improve the stifled injection of the lymph stasis of blood, raw material are as follows: 1-2 parts of collagen, 2-4 parts of Radix Astragali, 2-4 parts of Radix Angelicae Sinensis, And 100-200 parts of physiological saline.
Embodiment 2
Improve the stifled injection of the lymph stasis of blood, raw material are as follows: 1 part of collagen protein powder, 2 parts of Radix Astragali, 2 parts of Radix Angelicae Sinensis and 100 parts of physiological saline.
Embodiment 3
Improve the stifled injection of the lymph stasis of blood, raw material are as follows: 2 parts of collagen protein powder, 4 parts of Radix Astragali, 4 parts of Radix Angelicae Sinensis, and 200 parts of physiological saline.The collagen is collagenocyte stoste.
Embodiment 4
Improve the stifled injection of the lymph stasis of blood, raw material are as follows: 1 part of collagen protein powder, 2 parts of astragalus injection, Radix Angelicae Sinensis note Penetrate 2 parts and 100 parts physiological saline of liquid.The collagen is collagenocyte stoste.
Embodiment 5
Injection, raw material are 3 parts of collagen protein powder, 2 parts of astragalus injection, 3 parts of Radix Angelicae Sinensis injection and 200 The compounding nutrient solution of the physiological saline composition of part.The collagen is collagenocyte stoste.It is stifled for the inguinal lymph stasis of blood.
Embodiment 6
Improve the stifled injection of the lymph stasis of blood, raw material are as follows: 1 part of collagen protein powder, 2 parts of astragalus injection, Radix Angelicae Sinensis note Penetrate the compounding nutrient solution of 2 parts and 100 parts of liquid of physiological saline composition.The collagen is collagenocyte stoste.For shoulder The neck lymph stasis of blood is stifled.
Embodiment 7
Improve the stifled injection of the lymph stasis of blood, raw material are as follows: 1 part of collagen protein powder, 2 parts of astragalus injection, Radix Angelicae Sinensis note Penetrate the compounding nutrient solution of 2 parts and 100 parts physiological saline of liquid composition.The collagen is collagenocyte stoste.For oxter The lymph stasis of blood is stifled.
The method for preparing above-mentioned injection includes the following steps:
(1) Radix Angelicae Sinensis traditional Chinese medicinal material raw materials are cleaned, drying;Medicinal material moisture content≤5% after step (1) drying;
(2) Radix Angelicae Sinensis just crushes, sieving;Step (2) the drug coarse powder passes through 200 meshes;
(3) it crushes, is sieved again;Step (3) medicinal powder passes through 800-1000 mesh;
(4) it is handled with ultra-fine lamination ball mill;Step (4) the processing time is 5-10min;
(5) angelica medicament extract is obtained by extraction;The step (5) selects supercritical fluid extraction instrument to be extracted, and extracts The supercritical fluid flow velocity for taking kettle is 35-45L/h, and temperature is 25-40 DEG C, pressure 35-46MPa, extraction time 5-6h;
(6) ultrasonic cut;Step (6) ultrasonic frequency is 70-130KHZ.
(7) collagen is dissolved in deionized water be made collagen aqueous solution and physiological saline mixing note is prepared Penetrate liquid.
Comparative test
Total includes user 1- user 7, and seven people participate in.
It is required that: the stifled injection of the lymph stasis of blood will be improved for each person every day and operate at least two lymph position, and dose is no more than 3 It is secondary.
In addition, the operation same day drinks water less as far as possible, glass urine is connect before operation and is retained, so that the next morning observes toxin expelling situation;
It is 3 times treatment phase, it is proposed that 40-60 days 1 time;Enter maintenance metabilic stage after 3 times, 3-4 months can be spaced once, It cannot operate too frequently.
The 1 lymph stasis of blood of table is stifled to improve test
Using volunteer as subjects, the lymph stasis of blood blocks up the experimental study of situation after being injected, and investigates Examples 1 to 4 The influence that injection under test conditions blocks up the lymph stasis of blood.Specific operating method is as described below:
The compounding nutrient solution that will be enriched in collagen, Radix Angelicae Sinensis injection and physiological saline is injected into the stifled region of the lymph stasis of blood, Wherein, collagen increases the degree of packing and elasticity of skin, tensioning the skin.Radix Angelicae Sinensis can accelerate blood and lymph with replenishing and activating blood It is stifled quickly to exclude toxin, the removing stasis of blood for circulation.It dredges channels and collaterals, fill blood, mitigate the five internal organs burden, reach coordinating yin and yang balance, moulded The effect of body beautification type.
The different lymph stasis of bloods of table 2 are stifled to improve test
Using volunteer as subjects, the experimental study of situation is blocked up after being injected to the different parts lymph stasis of blood, is investigated real Apply the injection influence to blocking up to the different parts lymph stasis of blood under test conditions of example 1~4.The specific following institute of operating method It states:
According to the stifled degree of the aging at shoulder neck and back and the lymph stasis of blood, is operated according to certain course for the treatment of, back can be passed through Health promotion body total health, slow down headache, fatiguability, symptoms, the back skin surface such as shoulder neck acid is swollen, trick is ice-cold Relaxation, too fat to move, lower extension shape chevron etc. can also obtain a degree of improvement.Abdomen and the dredging of the lymph of leg, Ke Yigai It is kind leg oedema, thick swollen, prevent varication.
The foregoing is merely preferred embodiment of the present application, are not intended to limit this application, for the skill of this field For art personnel, various changes and changes are possible in this application.Within the spirit and principles of this application, made any to repair Change, equivalent replacement, improvement etc., should be included within the scope of protection of this application.

Claims (9)

1. a kind of improve the stifled injection of the lymph stasis of blood, which is characterized in that including following weight parts raw material: 1-2 parts of collagen, yellow 2-4 parts of stilbene, 2-4 parts and 100-200 parts physiological saline of Radix Angelicae Sinensis.
2. the improvement lymph stasis of blood according to claim 1 blocks up injection, which is characterized in that Radix Angelicae Sinensis injection is made in the Radix Angelicae Sinensis Liquid.
3. the improvement lymph stasis of blood according to claim 1 blocks up injection, which is characterized in that astragalus injection is made in the Radix Astragali Liquid.
4. improving the stifled injection of the lymph stasis of blood according to claim 1, which is characterized in that collagen is made in the collagen Cell stoste.
5. improving the stifled injection of the lymph stasis of blood according to claim 1, which is characterized in that stifled for the inguinal lymph stasis of blood.
6. improving the stifled injection of the lymph stasis of blood according to claim 1, which is characterized in that stifled for the shoulder neck lymph stasis of blood.
7. improving the stifled injection of the lymph stasis of blood according to claim 1, which is characterized in that stifled for the axillary lymph stasis of blood.
8. a kind of method for preparing injection described in claim 1, which comprises the steps of: (1) Chinese medicine is former Material is cleaned, drying;(2) it just crushes, is sieved;(3) it crushes, is sieved again;(4) it is handled with ultra-fine lamination ball mill;(5) it extracts Obtain drug extract;(6) ultrasonic cut;(7) collagen is dissolved in deionized water and collagen aqueous solution and life is made Injection is prepared in reason salt water mixing.
9. the method for injection according to claim 8, which is characterized in that medicinal material moisture content after step (1) drying ≤ 5%;Step (2) the drug coarse powder passes through 200 meshes;Step (3) medicinal powder passes through 800-1000 mesh;The step (4) the processing time is 5-10min;The step (5) selects supercritical fluid extraction instrument to be extracted, the shooting flow of extraction kettle Body flow velocity is 35-45L/h, and temperature is 25-40 DEG C, pressure 35-46MPa, extraction time 5-6h;Step (6) ultrasound Wave frequency rate is 70-130KHZ.
CN201910194581.XA 2019-03-14 2019-03-14 Improve the stifled injection and preparation method thereof of the lymph stasis of blood Pending CN110170040A (en)

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CN102579560A (en) * 2010-05-29 2012-07-18 甘肃中医学院 Preparation method of Chinese angelica and astragalus mongholicus mixture aqueous extract, as well as application in intervening in pulmonary fibrosis
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