CN109568154A - A kind of capsule housing and the fragrant soft capsule of lock prepared therefrom and preparation method thereof - Google Patents

A kind of capsule housing and the fragrant soft capsule of lock prepared therefrom and preparation method thereof Download PDF

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Publication number
CN109568154A
CN109568154A CN201811627442.3A CN201811627442A CN109568154A CN 109568154 A CN109568154 A CN 109568154A CN 201811627442 A CN201811627442 A CN 201811627442A CN 109568154 A CN109568154 A CN 109568154A
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Prior art keywords
capsule
parts
soft capsule
gelatin
preparation
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Chinese (zh)
Inventor
周洋
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HANGYANG HEALTH CO Ltd
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HANGYANG HEALTH CO Ltd
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Priority to CN201811627442.3A priority Critical patent/CN109568154A/en
Publication of CN109568154A publication Critical patent/CN109568154A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11Encapsulated compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/817Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to capsule preparation fields, and in particular to a kind of capsule housing and the fragrant soft capsule of lock prepared therefrom and preparation method thereof.Capsule housing provided by the invention, including the following raw material: gelatin, glycerine, polyethylene glycol 400 and/or propylene glycol, pulullan polysaccharide, PVPK30.Soft capsule component of the present invention is simple, raw material is cheap and easily-available, can effectively prevent essential oil volatilization, and the soft capsule is stablized, is not easy to chap, deforms, leak.

Description

A kind of capsule housing and the fragrant soft capsule of lock prepared therefrom and preparation method thereof
Technical field
The present invention relates to capsule preparation fields, and in particular to the fragrant soft capsule of a kind of capsule housing and lock prepared therefrom and its Preparation method.
Background technique
With the raising of life and educational level, cosmetics are increasingly valued by people.Due to natural cosmetics function It imitates, Small side effects and without allergic phenomena, there are superiority more more than the cosmetics of synthesis, so being with natural plant composition Main cosmetics are increasingly by the favor of the majority of consumers.In recent years, it is made and is made up with the plant extracts ingredient such as Chinese herbal medicine The research report of product increases increasingly.As many plants essential oils moisten, moisturizing, cleaning and it is antifreeze in terms of have obviously to human skin Effect.
Plants essential oil is also known as volatile oil or essential oil, is the oily liquid with peculiar aromatic odor being obtained by extraction in plant Body may be from herbal flower, bud, leaf, branch, root, bark, fruit, seed and resin etc..It is general to be steamed by vapor It evaporates, organic reagent extracts, the methods of vacuum topping and supercritical extract obtain.Plants essential oil it is sufficiently complex at being grouped as, Usually have tens to hundreds of compound.The chemical component of plants essential oil is generally divided into 4 kinds: terpenoid, aromatic compound Object, aliphatic compound, nitrogenous sulfur-containing compound.With the continuous development of scientific level, analyzed by various advanced instruments The essential oil being extracted from plants, understand in various essential oil or plant extraction liquid containing fragrant component or other can be used for cosmetics neck The natural component in domain is deployed into various skin care item, cosmetology shampoo and perfume etc., constantly releases cosmetics new product Kind, so that essential oil, which is extracted from plants, very wide prospect.Close is become for the research of cosmetics for plants essential oil Hot spot over year.
However, the plants essential oil for cosmetics is easy to volatilization, the holding time is short, so that application of the essential oil in cosmetics It is restricted, the preservation and utilization of essential oil have problem.General essential oil uses bottled in the prior art, takes every time easily Cause the volatilization and waste of essential oil.Although presently, there are stablize plants essential oil, prior art preparation plants essential oil by capsule Capsule is complicated, and capsule persistence is poor.
Summary of the invention
It is an object of the invention to overcome in the prior art, essential oil is volatile, stablizes that essential oil effect is poor, capsule by capsule The problem of complicated component, and then provide a kind of capsule contents are simple, stability is good capsule housing and lock prepared therefrom is fragrant soft Capsule and preparation method thereof.
In order to achieve the above objectives, the present invention adopts the following technical scheme:
A kind of capsule housing, the raw material including following parts by weight:
40-42 parts of gelatin,
16-20 parts of glycerine,
Polyethylene glycol 400 and/or 0.01-3 parts of propylene glycol,
1-3 parts of pulullan polysaccharide,
0.1-2 parts of PVPK30.
Preferably, including the following raw material:
40-42 parts of gelatin,
16-18 parts of glycerine,
Polyethylene glycol 400 and/or 1-3 parts of propylene glycol,
2-3 parts of pulullan polysaccharide,
1-2 parts of PVPK30.
Preferably, the mass ratio of the gelatin and pulullan polysaccharide is 15-18:1.
Preferably, the gelatin is bone glue.
It preferably, further include 40-42 parts of water.
The present invention also provides a kind of fragrant soft capsules of lock, including, capsule housing described above, and
Capsule 's content, the capsule 's content include organic plant extract fine oil.
Preferably, the organic plant extracts essential oil and is selected from little Hua refined jasmine oil, Lavender, sweet orange oil and the wide leaves of pulse plants One of essential oil is a variety of.
The present invention also provides a kind of preparation methods described above for locking fragrant soft capsule, include the following steps:
1) be soaked in water gelatin, heats up after immersion, and it is more that glycerine, polyethylene glycol 400 and/or propylene glycol, Propiram is added Sugar and PVPK30, deaerate after mixing evenly, obtain glue;
2) glue obtained by step 1) is pressed into film, by film injection molding, rapidly joins capsule 's content, closing is opened Mouthful, fragrant soft capsule must be locked.
Preferably, be soaked in water in step 1) gelatin temperature be 5-15 DEG C;Soaking time is 2-8 hours.
Preferably, temperature is increased after impregnating in step 1) to 60-70 DEG C.
Preferably, film stock thickness described in step 2) is 0.5-0.8mm.
PVPK30 of the present invention is pharmaceutical grade polyvinylpyrrolidone, and the water is pure water.
The invention has the advantages that:
1, soft capsule component of the present invention is simple, raw material is cheap and easily-available, can effectively prevent essential oil volatilization, the soft capsule Stablize, is not easy to chap, deforms, leak.Use in conjunction animal glue and natural plant gum of the present invention cooperate with other components, from The stability of soft capsule is improved on the whole.
2, the present invention uses bone glue and pulullan polysaccharide, and animal glue and natural plant gum cooperate, and effectively increases flexible glue The stability of capsule is suitable for Islamic vegetarian.Further, when the mass ratio of the bone glue and pulullan polysaccharide is When 15-18:1, the stability of soft capsule is further increased.
3, essential oil of the present invention preferably uses organic plant to extract essential oil, and the soft capsule can effectively prevent essential oil fragrance It overflows, prevents essential oil from volatilizing.When capsule closing, odorless, tasteless;When capsule is opened, the distinctive fragrance of essential oil overflows, and can release It is put into air.Essential oil of the present invention has the effect of firm skin, gentle skin, additionally has the function such as desalination striae of pregnancy Effect.
4, the preparation method of soft capsule of the present invention is simple, and closed soft capsule can completely cut off air, so that in air Oxygen does not influence the effect of essential oil effect, ensure that the stability of essential oil, the function therapeutic effect of essential oil are not in reduce.
Specific embodiment
There is provided following embodiments is to preferably further understand the present invention, it is not limited to the best embodiment party Formula is not construed as limiting the contents of the present invention and protection scope, anyone under the inspiration of the present invention or by the present invention and its The feature of his prior art is combined and any and identical or similar product of the present invention for obtaining, all falls within of the invention Within protection scope.
Specific experiment step or condition person are not specified in embodiment, according to the literature in the art described routine experiment The operation of step or condition can carry out.Reagents or instruments used without specified manufacturer, being can be by commercially available acquisition Conventional reagent product.
Embodiment 1
A kind of fragrant soft capsule of lock, including capsule housing, the capsule housing includes the following raw material: bone glue 40g, glycerine 16g, polyethylene glycol 400 1.5g, propylene glycol 1.5g, pulullan polysaccharide 1g, PVPK30 2g, pure water 42g.
The fragrant soft capsule of the lock further includes capsule 's content, and the capsule 's content contains Pogostemon cablin essential and lavender essence Oil.
The preparation method described above for locking fragrant soft capsule, includes the following steps:
1) it is impregnated bone glue 8 hours at 15 DEG C with pure water, temperature is increased after sufficiently impregnating to 70 DEG C, is added the third three Alcohol, polyethylene glycol 400, propylene glycol, pulullan polysaccharide and PVPK30 are stirred 40 minutes, and uniformly rear degassing to be mixed pumps bubble Glue is obtained afterwards;
2) film that glue obtained by step 1) is pressed into 0.8mm thickness through opening up rubber tire, by film injection molding, closing injection molding Capsule lower end after molding, rapidly joins capsule 's content, and quick closure capsule open forms closed soft capsule to get lock Fragrant soft capsule.
Continuous stability investigation is carried out to the soft capsule that above-described embodiment obtains.Research shows that soft capsule is at 37 DEG C, humidity Under conditions of 50%, Coutinuous store 90 days in senile experiment case, crack-free leakage phenomenon Coutinuous store 180 days, occurs slight broken Split leakage phenomenon.The soft capsule that above-described embodiment is obtained is put into 60 DEG C of water, can be melted within 30 minutes, and content overflows.
Embodiment 2
A kind of fragrant soft capsule of lock, including capsule housing, the capsule housing includes the following raw material: bone glue 42g, glycerine 20g, polyethylene glycol 400 0.005g, propylene glycol 0.005g, pulullan polysaccharide 3g, PVPK30 0.1g, pure water 40g.
The fragrant soft capsule of the lock further includes capsule 's content, and the capsule 's content contains Pogostemon cablin essential and lavender essence Oil.
The preparation method described above for locking fragrant soft capsule, includes the following steps:
1) it is impregnated bone glue 2 hours with pure water at 5 DEG C, temperature is increased after sufficiently impregnating to 60 DEG C, is added the third three Alcohol, polyethylene glycol 400, propylene glycol, pulullan polysaccharide and PVPK30 are stirred 40 minutes, and uniformly rear degassing to be mixed pumps bubble Glue is obtained afterwards;
2) film that glue obtained by step 1) is pressed into 0.5mm thickness through opening up rubber tire, by film injection molding, closing injection molding Capsule lower end after molding, rapidly joins capsule 's content, and quick closure capsule open forms closed soft capsule to get lock Fragrant soft capsule.
Continuous stability investigation is carried out to the soft capsule that above-described embodiment obtains.Research shows that soft capsule is at 37 DEG C, humidity Under conditions of 50%, Coutinuous store 90 days in senile experiment case, crack-free leakage phenomenon Coutinuous store 180 days, occurs slight broken Split leakage phenomenon.The soft capsule that above-described embodiment is obtained is put into 60 DEG C of water, can be melted within 35 minutes, and content overflows.
Embodiment 3
A kind of fragrant soft capsule of lock, including capsule housing, the capsule housing includes the following raw material: bone glue 41g, glycerine 18g, polyethylene glycol 400 0.5g, propylene glycol 0.5g, pulullan polysaccharide 2g, PVPK30 1g, pure water 41g.
The fragrant soft capsule of the lock further includes capsule 's content, and the capsule 's content contains Pogostemon cablin essential and lavender essence Oil.
The preparation method described above for locking fragrant soft capsule, includes the following steps:
1) it is impregnated bone glue 6 hours at 10 DEG C with pure water, temperature is increased after sufficiently impregnating to 65 DEG C, is added the third three Alcohol, polyethylene glycol 400, propylene glycol, pulullan polysaccharide and PVPK30 are stirred 30 minutes, and uniformly rear degassing to be mixed pumps bubble Glue is obtained afterwards;
2) film that glue obtained by step 1) is pressed into 0.6mm thickness through opening up rubber tire, by film injection molding, closing injection molding Capsule lower end after molding, rapidly joins capsule 's content, and quick closure capsule open forms closed soft capsule to get lock Fragrant soft capsule.
Continuous stability investigation is carried out to the soft capsule that above-described embodiment obtains.Research shows that soft capsule is at 37 DEG C, humidity Under conditions of 50%, Coutinuous store 90 days in senile experiment case, crack-free leakage phenomenon Coutinuous store 180 days, occurs slight broken Split leakage phenomenon.The soft capsule that above-described embodiment is obtained is put into 60 DEG C of water, can be melted within 25 minutes, and content overflows.
Embodiment 4
A kind of fragrant soft capsule of lock, including capsule housing, the capsule housing includes the following raw material: bone glue 42g, glycerine 18g, polyethylene glycol 400 0.5g, propylene glycol 0.5g, pulullan polysaccharide 2.8g, PVPK30 1g, pure water 41g.
The fragrant soft capsule of the lock further includes capsule 's content, and the capsule 's content contains Pogostemon cablin essential and lavender essence Oil.
The preparation method described above for locking fragrant soft capsule, includes the following steps:
1) it is impregnated bone glue 6 hours at 10 DEG C with pure water, temperature is increased after sufficiently impregnating to 65 DEG C, is added the third three Alcohol, polyethylene glycol 400, propylene glycol, pulullan polysaccharide and PVPK30 are stirred 30 minutes, and uniformly rear degassing to be mixed pumps bubble Glue is obtained afterwards;
2) film that glue obtained by step 1) is pressed into 0.6mm thickness through opening up rubber tire, by film injection molding, closing injection molding Capsule lower end after molding, rapidly joins capsule 's content, and quick closure capsule open forms closed soft capsule to get lock Fragrant soft capsule.
Continuous stability investigation is carried out to the soft capsule that above-described embodiment obtains.Research shows that soft capsule is at 37 DEG C, humidity Under conditions of 50%, Coutinuous store 90 days in senile experiment case, crack-free leakage phenomenon, Coutinuous store 180 days, crack-free leakage Phenomenon.The soft capsule that above-described embodiment is obtained is put into 60 DEG C of water, can be melted within 20 minutes, and content overflows.
Embodiment 5
A kind of fragrant soft capsule of lock, including capsule housing, the capsule housing includes the following raw material: bone glue 41.4g, and the third three Alcohol 18g, polyethylene glycol 400 0.5g, propylene glycol 0.5g, pulullan polysaccharide 2.3g, PVPK30 1g, pure water 41g.
The fragrant soft capsule of the lock further includes capsule 's content, and the capsule 's content contains Pogostemon cablin essential and lavender essence Oil.
The preparation method described above for locking fragrant soft capsule, includes the following steps:
1) it is impregnated bone glue 6 hours at 10 DEG C with pure water, temperature is increased after sufficiently impregnating to 65 DEG C, is added the third three Alcohol, polyethylene glycol 400, propylene glycol, pulullan polysaccharide and PVPK30 are stirred 30 minutes, and uniformly rear degassing to be mixed pumps bubble Glue is obtained afterwards;
2) film that glue obtained by step 1) is pressed into 0.6mm thickness through opening up rubber tire, by film injection molding, closing injection molding Capsule lower end after molding, rapidly joins capsule 's content, and quick closure capsule open forms closed soft capsule to get lock Fragrant soft capsule.
Continuous stability investigation is carried out to the soft capsule that above-described embodiment obtains.Research shows that soft capsule is at 37 DEG C, humidity Under conditions of 50%, Coutinuous store 90 days in senile experiment case, crack-free leakage phenomenon, Coutinuous store 180 days, crack-free leakage Phenomenon.The soft capsule that above-described embodiment is obtained is put into 60 DEG C of water, can be melted within 20 minutes, and content overflows.
Comparative example 1
A kind of fragrant soft capsule of lock, including capsule housing, the capsule housing includes the following raw material: bone glue 41g, glycerine 18g, polyethylene glycol 400 0.5g, propylene glycol 0.5g, PVPK30 1g, pure water 41g.
The fragrant soft capsule of the lock further includes capsule 's content, and the capsule 's content contains Pogostemon cablin essential and lavender essence Oil.
The preparation method described above for locking fragrant soft capsule, includes the following steps:
1) it is impregnated bone glue 6 hours at 10 DEG C with pure water, temperature is increased after sufficiently impregnating to 65 DEG C, is added the third three Alcohol, polyethylene glycol 400, propylene glycol and PVPK30 are stirred 30 minutes, and uniformly rear degassing to be mixed obtains glue after pumping bubble;
2) film that glue obtained by step 1) is pressed into 0.6mm thickness through opening up rubber tire, by film injection molding, closing injection molding Capsule lower end after molding, rapidly joins capsule 's content, and quick closure capsule open forms closed soft capsule to get lock Fragrant soft capsule.
Continuous stability investigation is carried out to the soft capsule that above-described embodiment obtains.Research shows that soft capsule is at 37 DEG C, humidity Under conditions of 50%, there is slight rupture leakage phenomenon in Coutinuous store 90 days in senile experiment case.Above-described embodiment is obtained Soft capsule is put into 60 DEG C of water, can be melted within 40 minutes, and content overflows.
Comparative example 2
A kind of fragrant soft capsule of lock, including capsule housing, the capsule housing includes the following raw material: bone glue 41g, glycerine 18g, polyethylene glycol 400 0.5g, propylene glycol 0.5g, guar gum 2g, PVPK30 1g, pure water 41g.
The fragrant soft capsule of the lock further includes capsule 's content, and the capsule 's content contains Pogostemon cablin essential and lavender essence Oil.
The preparation method described above for locking fragrant soft capsule, includes the following steps:
1) it is impregnated bone glue 6 hours at 10 DEG C with pure water, temperature is increased after sufficiently impregnating to 65 DEG C, is added the third three Alcohol, polyethylene glycol 400, propylene glycol, guar gum and PVPK30 are stirred 30 minutes, and uniformly rear degassing to be mixed obtains after pumping bubble Glue;
2) film that glue obtained by step 1) is pressed into 0.6mm thickness through opening up rubber tire, by film injection molding, closing injection molding Capsule lower end after molding, rapidly joins capsule 's content, and quick closure capsule open forms closed soft capsule to get lock Fragrant soft capsule.
Continuous stability investigation is carried out to the soft capsule that above-described embodiment obtains.Research shows that soft capsule is at 37 DEG C, humidity Under conditions of 50%, there is slight rupture leakage phenomenon in Coutinuous store 90 days in senile experiment case.Above-described embodiment is obtained Soft capsule is put into 60 DEG C of water, can be melted within 45 minutes, and content overflows.
Obviously, the above embodiments are merely examples for clarifying the description, and does not limit the embodiments.It is right For those of ordinary skill in the art, can also make on the basis of the above description it is other it is various forms of variation or It changes.There is no necessity and possibility to exhaust all the enbodiments.And it is extended from this it is obvious variation or It changes still within the protection scope of the invention.

Claims (10)

1. a kind of capsule housing, which is characterized in that the raw material including following parts by weight:
40-42 parts of gelatin,
16-20 parts of glycerine,
Polyethylene glycol 400 and/or 0.01-3 parts of propylene glycol,
1-3 parts of pulullan polysaccharide,
0.1-2 parts of PVPK30.
2. capsule housing according to claim 1, which is characterized in that including the following raw material:
40-42 parts of gelatin,
16-18 parts of glycerine,
Polyethylene glycol 400 and/or 1-3 parts of propylene glycol,
2-3 parts of pulullan polysaccharide,
1-2 parts of PVPK30.
3. capsule housing according to claim 1 or 2, which is characterized in that the mass ratio of the gelatin and pulullan polysaccharide For 15-18:1.
4. capsule housing according to claim 1 to 3, which is characterized in that the gelatin is bone glue.
5. capsule housing according to claim 1 to 4, which is characterized in that further include 40-42 parts of water.
6. a kind of fragrant soft capsule of lock, which is characterized in that including, any capsule housing of claim 1-5, and
Capsule 's content, the capsule 's content include organic plant extract fine oil.
7. the fragrant soft capsule of lock according to claim 6, which is characterized in that the organic plant extracts essential oil and is selected from little Hua jasmine One of jasmine essential oil, Lavender, sweet orange oil and Pogostemon cablin essential are a variety of.
8. a kind of claim 6 or 7 preparation method for locking fragrant soft capsule, which comprises the steps of:
1) be soaked in water gelatin, heats up after immersion, be added glycerine, polyethylene glycol 400 and/or propylene glycol, pulullan polysaccharide and PVPK30 deaerates after mixing evenly, obtains glue;
2) glue obtained by step 1) being pressed into film, by film injection molding, rapidly joins capsule 's content, closing is open, Fragrant soft capsule must be locked.
9. locking the preparation method of fragrant soft capsule according to claim 8, which is characterized in that be soaked in water gelatin in step 1) Temperature is 5-15 DEG C;Soaking time is 2-8 hours.
10. locking the preparation method of fragrant soft capsule according to claim 9, which is characterized in that increase temperature after impregnating in step 1) Degree is to 60-70 DEG C.
CN201811627442.3A 2018-12-28 2018-12-28 A kind of capsule housing and the fragrant soft capsule of lock prepared therefrom and preparation method thereof Pending CN109568154A (en)

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Publication number Priority date Publication date Assignee Title
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CN103961335A (en) * 2014-05-22 2014-08-06 山东津美生物科技有限公司 Pulullan soft capsule and preparation method thereof
CN104721170A (en) * 2015-04-01 2015-06-24 广州宅家日用品有限公司 Mixed gum chewing type soft capsule and preparation method thereof
CN104940163A (en) * 2015-06-24 2015-09-30 陈威宇 Capsule shell
CN106176326A (en) * 2010-06-25 2016-12-07 奇华顿股份有限公司 The method manufacturing microcapsule

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1634095A (en) * 2004-11-04 2005-07-06 仵博 Gynostemme pentaphylium soft capsule and its preparing process
CN106176326A (en) * 2010-06-25 2016-12-07 奇华顿股份有限公司 The method manufacturing microcapsule
CN103961335A (en) * 2014-05-22 2014-08-06 山东津美生物科技有限公司 Pulullan soft capsule and preparation method thereof
CN104721170A (en) * 2015-04-01 2015-06-24 广州宅家日用品有限公司 Mixed gum chewing type soft capsule and preparation method thereof
CN104940163A (en) * 2015-06-24 2015-09-30 陈威宇 Capsule shell

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
高丹丹等: "普鲁兰多糖_明胶复合材料对油脂贮藏品质的影响", 《 农产品加工(创新版)》 *

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