CN109566661A - Expelling parasite bacteriostatic gel and preparation method thereof - Google Patents
Expelling parasite bacteriostatic gel and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
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- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
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- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/06—Oxygen or sulfur directly attached to a cycloaliphatic ring system
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- A—HUMAN NECESSITIES
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- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
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- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
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Abstract
The present invention relates to a kind of expelling parasite bacteriostatic gels and preparation method thereof.Expelling parasite bacteriostatic gel includes following each component: natural plant extracts, gel-type vehicle and purified water, natural plant extracts in Camphora extract, big vast eucalyptus Cinnomomum Sps. Extract and borneol extract at least two.Above-mentioned expelling parasite bacteriostatic gel includes natural plant extracts, has the function of warding off that foul, antipruritic, expelling parasite is antibacterial.D-Bomeol in borneol extract has antibacterial, inducing resuscitation of having one's ideas straightened out, cool pain-alleviating.The each component compatibility of above-mentioned expelling parasite bacteriostatic gel is reasonable, contains readily volatilized aroma type substance, not only has effects that long-acting mosquito-driving, but also have antibacterial effect, has good fungistatic effect to gram-positive bacteria and Gram-negative bacteria.In addition, the above-mentioned equal source extracted form natural plant of expelling parasite bacteriostatic gel, has very high safety, has no adverse reaction after use.
Description
Technical field
The present invention relates to gel technique fields, more particularly to a kind of expelling parasite bacteriostatic gel and preparation method thereof.
Background technique
Dormancy mosquito being easy in wardrobe, especially in temperature lower winter, wardrobe more mosquito provides the breeding ground passed the winter,
Bad clothing can not only be stung by hiding the mosquito in wardrobe, but also can be multiplied worm's ovum in wardrobe, be spread the disease, the severe jamming mankind
Normal life.
Most of wardrobe insect repellent products only have the function of insect prevention, mothproof, mould proof on the market, and it is antibacterial not have expelling parasite
Effect.
Summary of the invention
Based on this, it is necessary to aiming at the problem that product antibacterial without effective expelling parasite, provide a kind of for expelling parasite bacteriostatic gel
And preparation method thereof.
A kind of expelling parasite bacteriostatic gel, the expelling parasite bacteriostatic gel include following each component: natural plant extracts, gel base
Matter and purified water, the natural plant extracts in Camphora extract, big vast eucalyptus Cinnomomum Sps. Extract and borneol extract at least
Two kinds.
Above-mentioned expelling parasite bacteriostatic gel includes natural plant extracts, wherein the natural camphor tree of effective component in Camphora extract
Cineole in brain, big vast eucalyptus Cinnomomum Sps. Extract, which all has, wards off effect foul, antipruritic, that expelling parasite is antibacterial.The right side in borneol extract
Revolving borneol has antibacterial, inducing resuscitation of having one's ideas straightened out, cool pain-alleviating.The each component compatibility of above-mentioned expelling parasite bacteriostatic gel is reasonable, and containing appearance
Volatile aroma type substance, not only has effects that long-acting mosquito-driving, but also has antibacterial effect, to gram-positive bacteria and
Gram-negative bacteria has good fungistatic effect.In addition, the above-mentioned equal source extracted form natural plant of expelling parasite bacteriostatic gel, has non-
Often high safety, has no adverse reaction after use.
In one of the embodiments, in parts by mass, the natural plant extracts are 5-30 parts, the gel-type vehicle
It is 20-80 parts for 0.5-10 parts, the purified water.
The natural plant extracts are Camphora extract, big vast eucalyptus Cinnomomum Sps. Extract and borneol in one of the embodiments,
Extract.
In one of the embodiments, in parts by mass, the Camphora extract be 2-10 part, the flood eucalyptus Cinnomomum Sps. Extract
For 0.5-10 parts, the borneol extract be 2.5-10 parts.
The gel-type vehicle is selected from carbomer, hydroxypropyl methyl cellulose, hydroxy ethyl fiber in one of the embodiments,
One of element, xanthan gum, dehydroxanthan, carragheen, agar are a variety of.
The quality of the natural camphor in the Camphora extract accounts for the Camphora extract in one of the embodiments,
Quality is 80% or more.
The quality of the d-Bomeol in the borneol extract accounts for the borneol extract in one of the embodiments,
Quality is 70% or more.
The cineole quality in the big vast eucalyptus Cinnomomum Sps. Extract accounts for the big vast eucalyptus Cinnomomum Sps. Extract in one of the embodiments,
Quality be 45% or more.
The present invention also provides a kind of preparation methods of expelling parasite bacteriostatic gel.
A kind of preparation method of expelling parasite bacteriostatic gel, the preparation method of the expelling parasite bacteriostatic gel include the following steps:
Gel-type vehicle is dissolved in the aqueous solution in purified water and being uniformly mixing to obtain gel-type vehicle, then by extracted form natural plant
Object is added in the aqueous solution of above-mentioned gel-type vehicle and stirs evenly, and adjusts pH to 5-8；Wherein, the natural plant extracts choosing
At least two from Camphora extract, big vast eucalyptus Cinnomomum Sps. Extract and borneol extract.
The preparation method of above-mentioned expelling parasite bacteriostatic gel is simple, only needs the mixing of two steps that expelling parasite bacteriostatic gel can be prepared,
Above-mentioned expelling parasite bacteriostatic gel includes natural plant extracts, and each component cooperates according to its proportion, and containing readily volatilized
Aroma type substance, not only have effects that long-acting mosquito-driving, but also there is antibacterial effect, to gram-positive bacteria and gram
Negative bacterium has good fungistatic effect.
It is described in one of the embodiments, that natural plant extracts are added in the aqueous solution of above-mentioned gel-type vehicle simultaneously again
The step of stirring evenly includes: natural plant extracts and solubilizer to be added in the aqueous solution of above-mentioned gel-type vehicle and stir
It is even.
Specific embodiment
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, below to specific reality of the invention
The mode of applying is described in detail.In the following description, numerous specific details are set forth in order to facilitate a full understanding of the present invention.But
The invention can be embodied in many other ways as described herein, and those skilled in the art can be without prejudice to this hair
Similar improvement is done in the case where bright intension, therefore the present invention is not limited by the specific embodiments disclosed below.
Unless otherwise defined, all technical and scientific terms used herein and belong to technical field of the invention
The normally understood meaning of technical staff is identical.Term as used herein in the specification of the present invention is intended merely to description tool
The purpose of the embodiment of body, it is not intended that in the limitation present invention.Term " and or " used herein includes one or more phases
Any and all combinations of the listed item of pass.
The present invention provides a kind of expelling parasite bacteriostatic gel, and the expelling parasite bacteriostatic gel includes following each component: natural plants mention
Object, gel-type vehicle and purified water are taken, the natural plant extracts are selected from Camphora extract, big vast eucalyptus Cinnomomum Sps. Extract and borneol and extract
At least two in object.It is appreciated that the natural plant extracts are the combination of Camphora extract and Hong An Cinnomomum Sps. Extract, institute
State the combination that natural plant extracts are big vast eucalyptus Cinnomomum Sps. Extract and borneol extract, it is preferable that the natural plant extracts are
The combination of Camphora extract, big vast eucalyptus Cinnomomum Sps. Extract and borneol extract three.
It is appreciated that conventional side can be used in the Camphora extract, borneol extract, big vast eucalyptus Cinnomomum Sps. Extract in the present invention
Method is extracted to obtain, such as extraction by steam distillation or microwave distillation method are extracted, and are no longer excessively repeated herein.
The expelling parasite bacteriostatic gel further includes the solubilizer of 5-30 mass parts in one of the embodiments,.Solubilizer can
To improve dissolubility of the natural plant extracts in gel-type vehicle and purified water.So that the grease in natural plant extracts
Preferably it is dissolved in gel-type vehicle and purified water.
The solubilizer is selected from Cremophor RH40, nonyl phenol polyethers -10, oleyl alcohol in one of the embodiments,
One of polyethers -20 and laureth -9 are a variety of.
Expelling parasite bacteriostatic gel includes following each component in one of the embodiments: in parts by mass, the natural plants
Extract is 5-30 parts, the gel-type vehicle is 0.5-10 parts, the purified water is 20-80 parts.
Expelling parasite bacteriostatic gel includes following each component in one of the embodiments: in parts by mass, the natural plants
Extract is 7-24 parts, the gel-type vehicle is 1-5 parts, the purified water is 20-40 parts.
Expelling parasite bacteriostatic gel includes following each component in one of the embodiments: in parts by mass: the camphor extracts
Object is 2-6 parts, the big vast eucalyptus Cinnomomum Sps. Extract is 1-8 parts, the borneol extract is 4-10 parts, the gel-type vehicle is 1-5 parts,
The purified water is 20-40 parts.
Expelling parasite bacteriostatic gel includes following each component in one of the embodiments: in parts by mass: the camphor extracts
Object is 4 parts, the big vast eucalyptus Cinnomomum Sps. Extract is 5 parts, the borneol extract is 6 parts, the gel-type vehicle is 3 parts, the solubilising
Agent is 15 parts, the purified water is 25 parts.
The gel-type vehicle is selected from carbomer, hydroxypropyl methyl cellulose, hydroxy ethyl fiber in one of the embodiments,
One of element, xanthan gum, dehydroxanthan, carragheen, agar are a variety of.
In one of the embodiments, in parts by mass, the natural plant extracts in one embodiment of the invention include: institute
State that Camphora extract is 2-10 parts, the big vast eucalyptus Cinnomomum Sps. Extract is 0.5-10 parts, the borneol extract is 2.5-10 parts.
In one of the embodiments, in parts by mass, the natural plant extracts in one embodiment of the invention include: institute
State that Camphora extract is 2-6 parts, the big vast eucalyptus Cinnomomum Sps. Extract is 1-8 parts, the borneol extract is 4-10 parts.
In one of the embodiments, in parts by mass, the natural plant extracts in one embodiment of the invention include: institute
State that Camphora extract is 4 parts, the big vast eucalyptus Cinnomomum Sps. Extract is 5 parts, the borneol extract is 6 parts.
Effective component is mainly natural camphor in Camphora extract, and natural camphor, which primarily serves, to be warded off foul, antipruritic, detumescence and stop
Bitterly, the antibacterial effect of mosquito repellent.
It is 80% or more that the quality of natural camphor, which accounts for the quality of the Camphora extract, in one of the embodiments,.It is excellent
Selection of land, the quality that the quality of natural camphor accounts for the Camphora extract is 85% or more, and further, the quality of natural camphor accounts for institute
The quality for stating Camphora extract is 85%-95%.
Effective component is mainly d-Bomeol in borneol extract, and d-Bomeol has antibacterial, inducing resuscitation of having one's ideas straightened out, refrigerant to stop
Bitterly, the effect of mosquito repellent.
The quality of the d-Bomeol in the borneol extract accounts for the borneol extract in one of the embodiments,
Quality is 70% or more.Preferably, the quality of the d-Bomeol in the borneol extract accounts for the quality of the borneol extract
It is 75% or more, further, the quality that the quality of the d-Bomeol in the borneol extract accounts for the borneol extract is
75%-95%.
Main component in big vast eucalyptus Cinnomomum Sps. Extract is cineole, and cineole is foul, antipruritic, swelling and pain relieving with warding off
Effect.
Cineole also known as 1-8 Cineole, cajuputole, cineole etc., chemical name 1,3, -2 oxa- of 3- trimethyl
Bicyclic [2,2,2] octane.It is not soluble in water for colourless or light yellow transparent liquid, but it is dissolved in ethyl alcohol, ether, chloroform, glacial acetic acid
Deng.With the special fragrance that diffusivity, camphor sample are cool.It is largely used in food flavor, can be used for configuring cosmetics, toothpaste, perfume (or spice)
The essence such as soap, detergent, cleaning agent for mouth cavity, indoor cleaning agent, chewing gum, Cinnamomum Camphora Oil's element or a kind of medicinal raw material.
The cineole quality in the big vast eucalyptus Cinnomomum Sps. Extract accounts for the big vast eucalyptus Cinnomomum Sps. Extract in one of the embodiments,
Quality be 45% or more.Preferably, the cineole quality in the big vast eucalyptus Cinnomomum Sps. Extract accounts for the big vast eucalyptus Cinnomomum Sps. Extract
Quality is 48% or more, and further, the cineole quality in the flood eucalyptus Cinnomomum Sps. Extract accounts for the big vast eucalyptus Cinnomomum Sps. Extract
Quality is 48%-55%.
Above-mentioned expelling parasite bacteriostatic gel includes natural plant extracts, wherein the natural camphor tree of effective component in Camphora extract
Cineole in brain, big vast eucalyptus Cinnomomum Sps. Extract, which all has, wards off effect foul, antipruritic, that expelling parasite is antibacterial.The right side in borneol extract
Revolving borneol has antibacterial, inducing resuscitation of having one's ideas straightened out, cool pain-alleviating.The each component compatibility of above-mentioned expelling parasite bacteriostatic gel is reasonable, and containing appearance
Volatile aroma type substance, not only has effects that long-acting mosquito-driving, but also has antibacterial effect, to gram-positive bacteria and
Gram-negative bacteria has good fungistatic effect.In addition, the above-mentioned equal source extracted form natural plant of expelling parasite bacteriostatic gel, has non-
Often high safety, has no adverse reaction after use.
The present invention also provides a kind of preparation methods of expelling parasite bacteriostatic gel.
A kind of preparation method of expelling parasite bacteriostatic gel, the preparation method of the expelling parasite bacteriostatic gel include the following steps:
Gel-type vehicle is dissolved in the aqueous solution in purified water and being uniformly mixing to obtain gel-type vehicle, then by extracted form natural plant
Object is added in the aqueous solution of above-mentioned gel-type vehicle and stirs evenly, and adjusts pH to 5-8；Wherein, the natural plant extracts choosing
At least two from Camphora extract, big vast eucalyptus Cinnomomum Sps. Extract and borneol extract.
Natural plant extracts are added in one of the embodiments, in the aqueous solution of above-mentioned gel-type vehicle and are stirred
It include: natural plant extracts and solubilizer to be added together in the aqueous solution of above-mentioned gel-type vehicle and are stirred in even process
It is even.
Include: by the aqueous solution process that above-mentioned gel-type vehicle is added in natural plant extracts in one of the embodiments,
First natural plant extracts are mixed with crosslinking agent according to mass ratio 1:1-1:3, obtain the drive for being embedded with natural plant extracts
Then the antibacterial embedded object of mosquito will be used to the antibacterial embedded object of mosquito repellent again and be added stir in the aqueous solution of above-mentioned gel-type vehicle equal
It is even.Such as: being used for natural plant extracts and crosslinking polymer according to mass ratio is 1:1,1:2 or 1:3.When natural plants mention
Take object and crosslinking polymer according to mass ratio be 1:2 when, embedding slow release effect it is best.
Wherein, crosslinking polymer has good surface-active cladding and minor matters effect, can be by above-mentioned natural plants
Extract embeds wherein, and then obtains stable polymer microsphere structure.Make crosslinking polymer loading functional ingredient in certainly
In body system, the action time of extension effective component is reached by slowly spreading, discharging the natural plant extracts in embedded object,
The double effects for extending the repellent time, reducing traditional mosquito component dosage can be played.
The crosslinking polymer is gelatin, chitosan or polylactic acid microsphere in one of the embodiments,.
A kind of preparation method of expelling parasite bacteriostatic gel in one of the embodiments, the preparation of the expelling parasite bacteriostatic gel
Method includes the following steps:
Taking mass parts is the purified water mixing swelling that 0.5-10 parts of gel-type vehicle is placed in that mass parts are 20-80 parts, is obtained
The aqueous solution of gel-type vehicle, then above-mentioned gel is added for 5-30 parts of solubilizer with mass parts by 5-30 parts of natural plant extracts
Stirred evenly in the aqueous solution of matrix, adjust pH to 5-8 to get.The natural plant extracts are selected from Camphora extract, Hong An
At least two in Cinnomomum Sps. Extract and borneol extract.
A kind of preparation method of expelling parasite bacteriostatic gel in one of the embodiments, the preparation of the expelling parasite bacteriostatic gel
Method includes the following steps:
The gel-type vehicle that mass parts are 0.5-10 parts is placed in the purified water that mass parts are 20-80 parts and is uniformly mixed so as to obtain gel base
The aqueous solution of matter, then the embedded object for being embedded with natural plant extracts is added in the aqueous solution of above-mentioned gel-type vehicle and is stirred
It is even, adjust pH to 5-8 to get.The natural plant extracts are selected from Camphora extract, the mass parts that mass parts are 2-10 parts
The borneol extract that big vast eucalyptus Cinnomomum Sps. Extract and mass parts for 0.5-10 parts are 2.5-10 parts.
A kind of preparation method of expelling parasite bacteriostatic gel in one of the embodiments, the preparation of the expelling parasite bacteriostatic gel
Method includes the following steps: to be that 6 parts of gel-type vehicle is placed in the purified water that mass parts are 60 parts and is uniformly mixed so as to obtain gel by mass parts
The aqueous solution of matrix, then the embedded object for being embedded with natural plant extracts is added in the aqueous solution of above-mentioned gel-type vehicle and is stirred
It is even, pH to 7 is adjusted to get the expelling parasite bacteriostatic gel.Wherein, the natural plant extracts include the camphor tree that mass parts are 7 parts
The borneol extract that the big vast eucalyptus Cinnomomum Sps. Extract and mass parts that brain extract, mass parts are 8 parts are 5 parts.Remaining embodiment is with such
It pushes away.
Cosmetic field technical staff can be selected commonly sour without limitation it is appreciated that adjusting the substance of pH value
PH is adjusted in alkali.Preferably, the pH value of above-mentioned expelling parasite bacteriostatic gel is adjusted using triethanolamine.Triethanolamine can be with
The acid Macromolecule gel matrix such as carbomer is neutralized, triethanolamine forms stable height by neutralizing with the carboxyl of carbomer
Molecular structure reaches the application effect of thickening and moisturizing in turn.
The preparation method of above-mentioned expelling parasite bacteriostatic gel is simple, only needs the mixing of two steps that expelling parasite bacteriostatic gel can be prepared,
Above-mentioned expelling parasite bacteriostatic gel includes natural plant extracts, and each component cooperates according to its proportion, and containing readily volatilized
Aroma type substance, not only have effects that long-acting mosquito-driving, but also there is antibacterial effect, to gram-positive bacteria and gram
Negative bacterium has good fungistatic effect.
In order to which objects and advantages of the present invention are more clearly understood, the present invention is carried out with reference to embodiments further
It is described in detail.It should be appreciated that described herein, specific examples are only used to explain the present invention, is not intended to limit the present invention.
Embodiment 1
A kind of preparation method of expelling parasite bacteriostatic gel, the preparation method of the expelling parasite bacteriostatic gel include the following steps:
Taking mass parts is that 1 part of carbomer is placed in the purified water that mass parts are 20 parts that be uniformly mixed so as to obtain carbomer gel water-soluble
Liquid, then natural plant extracts are added in above-mentioned carbomer gel aqueous solution and are stirred evenly, pH to 7 is adjusted with triethanolamine,
To obtain the final product.The group of natural plant extracts becomes the Camphora extract (containing natural camphor 70%) that mass parts are 4 parts and mass parts are
2.5 parts of borneol extract (containing d-Bomeol 68%).
Embodiment 2
A kind of preparation method of expelling parasite bacteriostatic gel, the preparation method of the expelling parasite bacteriostatic gel include the following steps:
Taking mass parts is that 1 part of carbomer is placed in the purified water that mass parts are 20 parts the water for being uniformly mixed so as to obtain carbomer gel
Solution, then the water-soluble of above-mentioned carbomer gel is added in natural plant extracts, the Cremophor RH40 that mass parts are 5 parts
Stirred evenly in liquid, with triethanolamine adjust pH to 6 to get.The group of natural plant extracts becomes the camphor that mass parts are 4 parts
The borneol extract (containing d-Bomeol 75%) that extract (containing natural camphor 80%) and mass parts are 2.5 parts.
Embodiment 3
A kind of preparation method of expelling parasite bacteriostatic gel, the preparation method of the expelling parasite bacteriostatic gel include the following steps:
Taking mass parts is that 1 part of carbomer is placed in the purified water that mass parts are 20 parts the water for being uniformly mixed so as to obtain carbomer gel
Solution, then the embedded object for being embedded with natural plant extracts is added in the aqueous solution of above-mentioned carbomer gel and is stirred evenly, it uses
Triethanolamine adjust pH to 6 to get.Wherein, embedded object is made of natural plant extracts and crosslinking polymer gelatin,
In, the mass ratio of natural plant extracts and crosslinking polymer gelatin is 1:2.The group of natural plant extracts becomes mass parts
(contain natural d-borneol for 4 parts of Camphora extracts (containing natural camphor 80%), the borneol extract that mass parts are 2.5 parts
80%).
Embodiment 4
A kind of preparation method of expelling parasite bacteriostatic gel, the preparation method of the expelling parasite bacteriostatic gel include the following steps:
Taking mass parts is that 8 parts of carbomer is placed in the purified water that mass parts are 40 parts the water for being uniformly mixed so as to obtain carbomer gel
Solution, then above-mentioned card wave is added in the laureth -9 for being embedded with the embedded object of natural plant extracts, mass parts are 28 parts
Stirred evenly in the aqueous solution of nurse gel, with triethanolamine adjust pH to 7 to get.Wherein, embedded object is by natural plant extracts
It is formed with crosslinking polymer gelatin, wherein the mass ratio of natural plant extracts and crosslinking polymer gelatin is 1:3.It
The group of right plant extracts becomes the Camphora extract (containing natural camphor 80%) that mass parts are 4 parts, the flood that mass parts are 5 parts
The borneol extract (containing natural d-borneol 90%) that eucalyptus Cinnomomum Sps. Extract (element containing Cinnamomum Camphora Oil 50%) and mass parts are 6 parts.
Embodiment 5
A kind of preparation method of expelling parasite bacteriostatic gel, the preparation method of the expelling parasite bacteriostatic gel include the following steps:
Taking mass parts is that 8 parts of carbomer is placed in the purified water that mass parts are 60 parts the gel for being uniformly mixed so as to obtain carbomer
In aqueous solution, then the addition of laureth -9 for being embedded with the embedded object of natural plant extracts, mass parts are 20 parts is above-mentioned
Stirred evenly in the aqueous solution of carbomer gel, with triethanolamine adjust pH to 7 to get.Wherein, embedded object is mentioned by natural plants
Object and crosslinking polymer gelatin is taken to form, wherein the mass ratio of natural plant extracts and crosslinking polymer gelatin is 1:
2.5.The group of natural plant extracts becomes the Camphora extract (containing natural camphor 90%) that mass parts are 8 parts, mass parts are 9 parts
Big vast eucalyptus Cinnomomum Sps. Extract (element containing Cinnamomum Camphora Oil 50%) and mass parts be 10 parts borneol extract (contain natural d-borneol
90%).
Comparative example 1
A kind of preparation method of expelling parasite bacteriostatic gel, the preparation method of the expelling parasite bacteriostatic gel substantially with 1 phase of embodiment
Together, the difference is that being free of Camphora extract in natural plant extracts.
Comparative example 2
A kind of preparation method of expelling parasite bacteriostatic gel, the preparation method of the expelling parasite bacteriostatic gel substantially with 1 phase of embodiment
Together, the difference is that being free of borneol extract in natural plant extracts.
Comparative example 3
A kind of preparation method of expelling parasite bacteriostatic gel, the preparation method of the expelling parasite bacteriostatic gel include the following steps:
Taking mass parts is that 1 part of carbomer is placed in the purified water that mass parts are 20 parts the water for being uniformly mixed so as to obtain carbomer gel
Solution, then big vast eucalyptus Cinnomomum Sps. Extract is added in the aqueous solution of above-mentioned carbomer gel and is stirred evenly, with triethanolamine adjust pH to
7 to get.
Performance test 1: insect esexpeling test
Test grouping: common powder post beetle in 160 wardrobes of selection, according to every group 10 of embodiment group and comparative example group only into
The random grouping of row.
Test method: preparing two test-cages being for experiment, be counted as A cage and B cage, the length of the specification of each cage × wide
× a height of 40cm × 40cm × 50cm, two test-cages are oppositely arranged, open up on the cage face of two test-cages being oppositely arranged
1cm2Door opening, creep between two cages for powder post beetle.The expelling parasite being put into embodiment group and comparative example group in A cage is antibacterial
Gel, and be put into powder post beetle in A cage and like the food bait eaten, 20 powder post beetles in every group are put into test-cage, B cage
Food bait and expelling parasite bacteriostatic gel are not put.When 1h and 2h, the quantity of powder post beetle in A cage is recorded, is specifically shown in Table 1.
Table 1
As shown in Table 1, either 1h or 2h, the powder post beetle quantity in 1 cage of embodiment group is than the powder moth in control group
Borer population amount is few, even if there is food bait attraction, the powder post beetle quantity in 1 cage of embodiment each group is still seldom, especially embodiment 3
Into embodiment 5, with the extension of time, the powder post beetle quantity in 1 cage tails off, a large amount of powder post beetle has gone to lure without food
Active principle natural plant extracts cross-linked polymer in the B cage of bait, in this gel with embodiment 3 into embodiment 5
Embed it is related so that the volatile ingredient in effective natural plant extracts is sustained, the effect of long-acting insect expelling.This
Outside, in embodiment 2, the d-Bomeol in natural camphor content and borneol extract in Camphora extract compares example 1 group
Middle height, anthelminthic effect are also obvious compared with example 1 group.And without crucial effectively anthelmintic ingredient Camphora extract in 1 group of comparative example, it is right
Without crucial effectively anthelmintic ingredient borneol extract in 2 groups of ratio, contain only big vast eucalyptus Cinnomomum Sps. Extract in 3 groups of comparative example, comparative example 1 to
It is good to be not so good as example 1 group effect for the anthelminthic effect of gel in 3 groups.And extract containing borneol, Camphora extract and Hong An camphor tree mention
Take the embodiment group of the natural plant extracts of object three than other embodiments group and control group good antimicrobial effect.
Performance test 2: bacteriostatic test
The present embodiment carries out extracorporeal bacteria inhibitor test to expelling parasite bacteriostatic gel prepared by embodiment 1-5, comparative example 1-3.
The selection of strain:
The strain of selection extracorporeal bacteria inhibitor test is respectively as follows: Escherichia coli, staphylococcus aureus.
Carrier quantitation bacteriostatic experiment:
By " disinfection technology standard " (version in 2002) carrier quantitation bacteriostatic test requirement, Example 1-5, comparative example 1-3
The gel of preparation acts on 20min, 60min, as a result see the table below 2.
Table 2
As shown in Table 2, the expelling parasite bacteriostatic gel in embodiment each group is compared to the expelling parasite bacteriostatic gel in comparative example each group
Bacteriostasis rate is high, good antimicrobial effect, i.e., either to using Escherichia coli as the Gram-negative bacteria of representative, or with golden yellow grape
Coccus is that the gram-positive bacteria of representative can play effectively antibacterial effect.Especially embodiment 3 is to embodiment 5 to effective
Natural plant extracts are embedded, and active principle can be sustained antibacterial, extend the antibacterial time, also, extract containing borneol,
The embodiment group of Camphora extract and the natural plant extracts of Hong An Cinnomomum Sps. Extract three is than other embodiments group and control group
Bacteriostasis rate is high, and fungistatic effect is good.
In addition, testing in person through different home housewife, above-mentioned expelling parasite bacteriostatic gel has very high safety, this is sent out
Expelling parasite bacteriostatic gel in bright is put into wardrobe, and mosquito quantity significantly reduces, and does not find worm's ovum in clothing, antibacterial in expelling parasite
While, make clothing that there is the distinctive fragrance of natural plant extracts.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention
Range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.
Claims (10)
1. a kind of expelling parasite bacteriostatic gel, which is characterized in that the expelling parasite bacteriostatic gel includes following each component: extracted form natural plant
Object, gel-type vehicle and purified water, the natural plant extracts are selected from Camphora extract, big vast eucalyptus Cinnomomum Sps. Extract and borneol extract
In at least two.
2. expelling parasite bacteriostatic gel according to claim 1, which is characterized in that in parts by mass, the extracted form natural plant
Object is 5-30 parts, the gel-type vehicle is 0.5-10 parts, the purified water is 20-80 parts.
3. expelling parasite bacteriostatic gel according to claim 1, which is characterized in that the natural plant extracts are camphor extraction
Object, big vast eucalyptus Cinnomomum Sps. Extract and borneol extract.
4. expelling parasite bacteriostatic gel according to claim 3, which is characterized in that in parts by mass, the Camphora extract is
2-10 parts, the big vast eucalyptus Cinnomomum Sps. Extract be 0.5-10 parts, the borneol extract is 2.5-10 parts.
5. expelling parasite bacteriostatic gel according to any one of claims 1 to 4, which is characterized in that the gel-type vehicle is selected from card
One of wave nurse, hydroxypropyl methyl cellulose, hydroxyethyl cellulose, xanthan gum, dehydroxanthan, carragheen, agar are more
Kind.
6. expelling parasite bacteriostatic gel according to any one of claims 1 to 4, which is characterized in that in the Camphora extract
The quality that the quality of natural camphor accounts for the Camphora extract is 80% or more.
7. expelling parasite bacteriostatic gel according to any one of claims 1 to 4, which is characterized in that in the borneol extract
The quality that the quality of d-Bomeol accounts for the borneol extract is 70% or more.
8. expelling parasite bacteriostatic gel according to any one of claims 1 to 4, which is characterized in that in the flood eucalyptus Cinnomomum Sps. Extract
Cineole quality to account for the quality of the big vast eucalyptus Cinnomomum Sps. Extract be 45% or more.
9. a kind of preparation method of expelling parasite bacteriostatic gel, which is characterized in that the preparation method of the expelling parasite bacteriostatic gel includes such as
Lower step:
Gel-type vehicle is dissolved in the aqueous solution in purified water and being uniformly mixing to obtain gel-type vehicle, then natural plant extracts are added
Enter in the aqueous solution of above-mentioned gel-type vehicle and stir evenly, adjusts pH to 5-8；Wherein, the natural plant extracts are selected from camphor tree
At least two in brain extract, big vast eucalyptus Cinnomomum Sps. Extract and borneol extract.
10. the preparation method of expelling parasite bacteriostatic gel according to claim 9, which is characterized in that described again by natural plants
It includes: by natural plant extracts and solubilizer that extract, which is added in the aqueous solution of above-mentioned gel-type vehicle and the step of stirring evenly,
It is added in the aqueous solution of above-mentioned gel-type vehicle and stirs evenly.
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| WO2021217324A1 (en) * | 2020-04-27 | 2021-11-04 | 陕西高源体外诊断试剂有限公司 | Disinfectant composition, preparation method therefor, and use thereof |
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