CN109562076B - 易于吞咽的涂层和涂覆有该涂层的底物 - Google Patents

易于吞咽的涂层和涂覆有该涂层的底物 Download PDF

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Publication number
CN109562076B
CN109562076B CN201780048719.4A CN201780048719A CN109562076B CN 109562076 B CN109562076 B CN 109562076B CN 201780048719 A CN201780048719 A CN 201780048719A CN 109562076 B CN109562076 B CN 109562076B
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China
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composition
guar gum
water
film coating
friction
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CN201780048719.4A
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English (en)
Chinese (zh)
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CN109562076A (zh
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J·R·金贝儿
D·杜
J·特克伊
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BPSI Holdings LLC
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BPSI Holdings LLC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
CN201780048719.4A 2016-08-04 2017-07-26 易于吞咽的涂层和涂覆有该涂层的底物 Active CN109562076B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662370944P 2016-08-04 2016-08-04
US62/370,944 2016-08-04
PCT/US2017/043923 WO2018026596A1 (en) 2016-08-04 2017-07-26 Easy to swallow coatings and substrates coated therewith

Publications (2)

Publication Number Publication Date
CN109562076A CN109562076A (zh) 2019-04-02
CN109562076B true CN109562076B (zh) 2022-01-28

Family

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Application Number Title Priority Date Filing Date
CN201780048719.4A Active CN109562076B (zh) 2016-08-04 2017-07-26 易于吞咽的涂层和涂覆有该涂层的底物

Country Status (11)

Country Link
US (1) US10232045B2 (https=)
EP (1) EP3474824B1 (https=)
JP (1) JP7041120B2 (https=)
KR (1) KR102437953B1 (https=)
CN (1) CN109562076B (https=)
AU (1) AU2017307194B2 (https=)
CA (1) CA3031671C (https=)
CO (1) CO2019000756A2 (https=)
MX (1) MX377902B (https=)
RU (1) RU2753049C2 (https=)
WO (1) WO2018026596A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3115516C (en) * 2018-10-05 2023-04-25 Isp Investments Llc Smooth high solids film coating composition comprising water soluble cellulose ether, process for preparing the same and method of use thereof
JP7317940B2 (ja) * 2019-03-04 2023-07-31 沢井製薬株式会社 フィルムコーティング組成物及び固形製剤
US11953458B2 (en) 2019-03-14 2024-04-09 Ecolab Usa Inc. Systems and methods utilizing sensor surface functionalization
US12427092B2 (en) 2020-11-05 2025-09-30 Purosil LLC Device and method for assisting pill swallowing

Family Cites Families (24)

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US4543370A (en) 1979-11-29 1985-09-24 Colorcon, Inc. Dry edible film coating composition, method and coating form
DE3220434A1 (de) 1982-05-29 1983-12-01 Robert Bosch Gmbh, 7000 Stuttgart Verfahren zur ueberwachung einer messgroesse
JP3165438B2 (ja) * 1990-04-04 2001-05-14 バーウィンド・ファーマス―ティカル・サーヴィスィーズ・インコーポレーテッド 水性のマルトデキストリン及びセルロースポリマーフィルムコーティング
US5114720A (en) 1990-12-27 1992-05-19 American Cyanamid Company Gelatin coated tablets and method for producing same
AU1195001A (en) 1999-10-11 2001-04-23 Monsanto Company Tablets coated with locust bean gum, guar gum or carrageenan gum
BRPI0511663A (pt) * 2004-06-07 2008-01-02 Wyeth Corp composição compreendendo água e um componente de sólidos, processo, e, tablete revestido
US8987438B2 (en) * 2006-07-20 2015-03-24 Rhodia Operations Method for making derivatized guar gum and derivatized guar gum made thereby
HUP0700826A3 (en) * 2007-12-20 2010-03-29 Richter Gedeon Nyrt Coated tablet containing drospirenone and process for producing the same
WO2009105409A2 (en) * 2008-02-19 2009-08-27 Mc Neil-Ppc, Inc. Dip coated compositions containing a starch having a high amylose content
WO2010052727A1 (en) * 2008-11-04 2010-05-14 Ideal Cures Private Limited High performance film coating compositions
US20100124568A1 (en) 2008-11-20 2010-05-20 Med-Eez, Inc Pharmaceutical articles coated with lubricious coatings
BR112012004372B1 (pt) * 2009-08-28 2020-06-02 Hercules Incorporated Composição de revestimento de filme a partir de compostos em pó sólido
KR101767288B1 (ko) * 2010-03-31 2017-08-10 모찌다 세이야쿠 가부시끼가이샤 복용 용이성 고형 제제
CA2807319C (en) 2010-08-18 2018-08-14 Mcneil-Ppc, Inc. Tablet sleeve for improved performance
MX357636B (es) * 2011-02-14 2018-07-17 Procter & Gamble Formas de dosificacion solidas que comprenden miel en el recubrimiento.
EA027819B1 (ru) * 2011-02-28 2017-09-29 Родиа Оперейшнс Покрытия семян, композиции покрытий и способы применения
CN102652738A (zh) * 2011-03-03 2012-09-05 天津聚贤投资有限公司 便于吞咽的新型药物外包皮
US20120328697A1 (en) * 2011-06-01 2012-12-27 Fmc Corporation Controlled Release Solid Dose Forms
US20130064889A1 (en) * 2011-09-13 2013-03-14 Aptapharma, Inc. Tablet-in-tablet Palperidone Formulations and Methods for Production and Use Thereof
WO2013046453A1 (ja) * 2011-09-30 2013-04-04 持田製薬株式会社 易服用性固形製剤
CN102430124B (zh) * 2011-11-24 2013-03-20 清华大学 一种具有超低摩擦系数的药丸涂层及其制备方法
CN104274409B (zh) * 2013-07-10 2017-11-03 北京科信必成医药科技发展有限公司 一种易于吞服的药物微球及其制备方法
RU2686183C2 (ru) 2014-01-21 2019-04-24 БиПиЭсАй ХОЛДИНГЗ, ЭлЭлСи Пленочные покрытия быстрого высвобождения, содержащие среднецепочечные глицериды, и покрытые ими субстраты
JP6294400B2 (ja) * 2016-07-19 2018-03-14 持田製薬株式会社 易服用性固形製剤

Also Published As

Publication number Publication date
US10232045B2 (en) 2019-03-19
JP2019523290A (ja) 2019-08-22
BR112019002040A2 (pt) 2019-05-07
US20180036413A1 (en) 2018-02-08
EP3474824A4 (en) 2019-07-31
KR102437953B1 (ko) 2022-08-29
JP7041120B2 (ja) 2022-03-23
KR20190035745A (ko) 2019-04-03
AU2017307194A1 (en) 2019-01-24
CA3031671C (en) 2024-10-29
EP3474824A1 (en) 2019-05-01
MX377902B (es) 2025-03-10
RU2019105589A3 (https=) 2020-09-04
WO2018026596A1 (en) 2018-02-08
CO2019000756A2 (es) 2019-02-08
RU2753049C2 (ru) 2021-08-11
MX2019001238A (es) 2019-04-25
RU2019105589A (ru) 2020-09-04
CA3031671A1 (en) 2018-02-08
AU2017307194B2 (en) 2022-06-23
CN109562076A (zh) 2019-04-02
EP3474824B1 (en) 2022-02-16

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