CN109529062A - A kind of Ultrasonography novel couplant - Google Patents

A kind of Ultrasonography novel couplant Download PDF

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Publication number
CN109529062A
CN109529062A CN201910047808.8A CN201910047808A CN109529062A CN 109529062 A CN109529062 A CN 109529062A CN 201910047808 A CN201910047808 A CN 201910047808A CN 109529062 A CN109529062 A CN 109529062A
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ultrasonography
radix
whin
borneol
honeysuckle
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高文娟
李明
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Individual
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics

Abstract

The invention discloses a kind of Ultrasonography novel couplants, group ingredient including following weight percent: chitin 1~3%, carbomer 4~4.5%, alginate 1.5~2%, polyethylene glycol 1~2%, alkyl-glucoside 1.5~2%, ethyl alcohol 3~4%, honeysuckle 2.5~3%, asparagus juice 2~3%, kuh-seng 0.5~1%, whin 2~2.5%, rheum officinale 1~1.5%, styrax 0.5~1.5%, Herba Lycopodii 1.5~2.5%, radix scutellariae 2~2.5%, Radix Glycyrrhizae 1~1.5%, borneol 1~1.5%, menthol 0.5~1%, evening primrose oil 1~1.5%, lanolin 2~2.5%, wild chrysanthemum 0.5-1%, Radix Angelicae Sinensis 0.5-1%, deionized water 69.5~75%, the present invention is by plurality of raw materials Mix and match, scientific composition, each raw material has complementary advantages, utilize its mutual collaboration or resistant function, it plays that greasy skin, activating microcirculation and removing stasis medicinal, inhibiting bacteria and diminishing inflammation, anti-corrosion be antipruritic, unique curative effect of myogenic sore, the moisturizings skin care ingredients such as aloe is added, reduce the stimulation to skin, nourishes rough skin, it is non-stimulated that there is high-effective disinfecting to sterilize, is safe and non-toxic.

Description

A kind of Ultrasonography novel couplant
Technical field
The present invention relates to couplant research and development technology fields, and in particular to a kind of Ultrasonography novel couplant.
Background technique
During ultrasonic examination, since the impedance difference between skin and probe is larger, cause reflection coefficient larger, then plus The presence of air between upper skin and probe enters in skin so that the transmitted acoustic pulse issued from probe passes through Air Interface Sound can be greatly reduced, and not only drive away air for this purpose, being often used couplant and being filled between detecting head surface and skin, but also can make to pop one's head in It is easy to slide in skin surface, and the couplant filled can also form the distortionless propagation ducts of ultrasonic wave, slow down sound energy Reduction, be more clear image.Therefore in medical domain using wide, for example two-dimentional color ultrasound, three-dimensional color ultrasound, heart are color Superfine inspection is often needed to using couplant.Couplant needs when in use and human contact, can take when contacting different people With some germs, the cross-infection between examiner, and operator and the user clothing easy to pollute when using couplant are caused Object comes difficult to the cleaning tape of clothing.
Summary of the invention
Technical problems based on background technology, the present invention provide a kind of Ultrasonography novel couplant, and Disinfection Effect is good, It does not stimulate mildly, stability is good, and environmental pollution degree is low.
Honeysuckle: resisting pathogenic microbes effect.To various pathogens such as staphylococcus aureus, hemolytic streptococcus, big Enterobacteria, shigella dysenteriae, comma bacillus, typhoid bacillus, paratyphosum Bacterium etc. have certain inhibiting effect.Anti inflammatory detoxication effect, There are stronger scattered carbuncle detumescence, clearing heat and detoxicating, antiinflammation to carbuncle swells furunculosis, acute appendicitis pulmonary abscess.It dredges heat and dissipates evil effect, to affection of exogenous wind-heat Or warm disease from the beginning of the headache of, body heat, it is vexed sleep less, the deep red, dry throat of coma tongue etc. has certain effect.The effect of removing heat from the blood and relieve diarrhea, to heat Fulminant dysentery disease, diarrhea purulence blood, damp-warm syndrome resistance larynx, abscess of throat etc. have the benefits of removing toxic substances stop dysentery cool blood relieving sore-throat.Honeysuckle tea is sweet in flavor, cold in nature, Has the function of clearing heat and detoxicating, dispelling wind and heat from the body.Honeysuckle plays the role of clearing heat and detoxicating, thin throat, relieving restlessness of relieving summer heat.Heat can be treated The diseases such as heat symptom-complex, dysentery, influenza, sore furuncle poison, acute and chronic tonsillitis, periodontitis.
Asparagus juice: aloe nutritional value is very high.Aloe contains a large amount of amino acid, vitamin, polysaccharide compound, various Enzyme and minerals have the function of bactericidal antiphlogistic, enhancing immune function, remove endotoxin and free radical, can release constipation, prevention Colitis, improves blood circulation, and acne-removing, skin-nourishing promotes whole body health.The body fluid of Healthy People is alkaline, informal dress aloe products energy Body fluid is set to maintain alkalinity, constitution of keeping fit.It daily intakes enough aloe products and also helps body reduction to grease in food Absorption, reach better loss of weight and toxin expelling purpose.
Kuh-seng: the plant belonged to for pulse family kuh-seng.It is distributed in the north and south of Russia, Japan, India, Korea and China's Mainland The ground such as each provinces and regions are grown on 1,500 meters of height above sea level of area, and more lifes are in hillside, sand ground, Cao Po, spinney and near field, mesh It is preceding not yet by artificial introducing and planting.Major function: heat-clearing and damp-drying drug, desinsection, diuresis.For hot dysentery, hematochezia, jaundice urodialysis is red white Leukorrhagia, swelling of vulva pruritus vulvae, eczema, wet sore, pruitus, castor；Trichomonas vaginitis is controlled outside.Deficiency-cold in spleen and stomach person avoids clothes.Stomach Weak person is used with caution.Long term usage energy loss kidney qi, liver, kidney deficiency and the person of having no high fever does not take.
Whin: whin is perennial herb, plant toughness.Stem is extremely short.The effect of pinnate compound leaf, whin includes: heat-clearing Removing toxic substances, myogenic are cured sore, weak thready hemostasis, defaecation.For treating plague, nosotoxicosis, grasserie, constipation, anthrax；It is swollen that boil is controlled in external application Bitterly.
Rheum officinale: being being collectively referred to as the perennial plant of a variety of polygonaceae Rheums, is born in mountainous region border or careless slope, likes dark and damp Environment, wild or cultivation.It is distributed in Shaanxi, the southeast of Gansu, Qinghai, western Sichuan, northwestern Yunnan Province and Eastern Tibet.Distribution In Gansu, Qinghai, Sichuan and Tibet northeast.It is distributed in Southern Shaanxi, West Henan, West of Hubei Province, Sichuan, Guizhou, Yunnan Etc. ground, effect include: the poison that purges heat, break stagnant, row hemostasis.Real heat constipation is controlled, delirious speech hair support, dyspepsia feeling of fullness, dysentery is from the beginning of inner urgency After weigh, stasis of blood menopause is closed, and a lump in the abdomen causing distension and pain, Shi Hangre epidemic disease, sudden and violent swelling ophthalmalgia, is spitted blood, and bleeding from five sense organs or subcutaneous tissue, yang jaundice, oedema, stranguria with turbid discharge urinates also, and large carbuncle is swollen Poison, furunculosis, burn.Purge heat logical intestines, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow.It is not well, damp and hot for real heat constipation, stagnant abdominal pain, dysentery Jaundice.
Styrax: the Chinese for Persian and Arabic is translated, and is originated in Central Asia Gu and is rested in peace state, Qiuci state, mortise state, Arab The peninsula and Iranian highland.Benzoic effect includes: inducing resuscitation of having one's ideas straightened out；Slit phlegm is warded off dirty；The promoting flow of qi and blood circulation；Analgesic.Wind phlegm Jue in master；It is frightened Epilepsy stupor, postpartum anemic fainting；Trusted subordinate's pain；The wandering arthritis arthrodynia of extremeties.For apoplexy coma due to blocking of the respiratory system, bstruction of the circulation of vital energy is fainted cruelly, middle evil is gone into a coma, trusted subordinate's pain, Postpartum anemic fainting, child convulsion.
Herba Lycopodii: for Menispermaceae Tinospora plant, it is distributed Guangdong, Guangxi and Yunnan.South East Asia Mainland, India and Si Lilan Card also has, and Herba Lycopodii is for treating rheumatic arthralgia, sciatica, lumbar muscle strain, traumatic injury.
Radix scutellariae: to be lamiaceae labiatae scutellaria herbaceos perennial, originating in Heilungkiang, Liaoning, the Inner Mongol, Hebei, Henan, Gansu, Shaanxi, Shanxi, Shandong, the ground such as Sichuan, north of China majority provinces and regions can all plant.Russia East Siberia, Mongolia, Korea, Japan are distributed.The effect of radix scutellariae includes heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention and other effects.Cure mainly warm heat disease, The infection of the upper respiratory tract, cough with lung heat, neonatal jaundice caused by dampness-heat, pneumonia, dysentery, hemoptysis, hot eyes, threatened abortion, hypertension, carbuncle swells furuncle sore etc. Disease.
Radix Glycyrrhizae: Glycyrrhiza perennial herb, root is sturdy with rhizomes, is a kind of help Chinese herbal medicine, in Asia, Europe, Australia The ground such as continent, America are all distributed.The effect of Radix Glycyrrhizae include: for the heart qi deficiency, palpitation and severe palpitation, knotted pulse and deficiency of spleen-QI and stomach-QI, it is tired It is idle out of strength；For ulcer sores, abscess of throat etc..It can be applied alone, take orally or be applied with；Radix Glycyrrhizae has similar cortex hormone of aadrenaline sample to make With.There is inhibiting effect to gastroxia caused by histamine；And there is hypo acid contained by antiacid Radix Glycyrrhizae that can block Induced by Carcinogen The effect and alleviation gastrointestinal smooth muscle spasm effect of tumour growth；Licoflavone, extract of licorice root and enoxolone have significantly Antitussive effect；Phlegm-dispelling functions are also more significant；There are also anti-inflammatory, anti-allergic effects for Radix Glycyrrhizae, can protect the throat and tunica mucosa tracheae of inflammation； Hypo acid contained by Radix Glycyrrhizae can block the effect of Induced by Carcinogen tumour growth.
Borneol: also known as piece brain, orange slices, L-Borneol, kapur, MEIHUA BINGPIAN, Dipterocarpus pilosus, plum blossom brain, borneol brain, Mei Bing Deng being through steam distillation and to be recrystallized and obtained by composite family Blumea balsamifera cauline leaf or lauraceae plant borneol camphor tree branches and leaves, the effect of borneol Include: antibacterial anti-inflammatory, there is powerful bacteriostasis.Liquid oedema can be excluded, anti-inflammatory is played the role of；Borneol acrid flavour It is cold, return heart spleen liver lung.Can inducing resuscitation of having one's ideas straightened out, removing nebula for improving eyesight.
Menthol: a kind of cyclic alcohol of saturation obtained in peppermint forms.With dispelling wind, the effect of heat-clearing, removing toxic substances. Be mainly used for treating headache and hot eyes, affection of exogenous wind-heat, pharynx tooth swelling and pain, the diseases such as skin pruritus, be usually used in manufacturing cooling ointment, anodyne, Toothpaste.
Evening primrose oil: being being squeezed by the seed of oenothera biennis through low temperature, color is in faint yellow.The ingredient of evening primrose oil is Linolenic acid, magnesium, zinc, injection Vitamin B_6, B6 etc. alleviate menstrual period various discomforts, are to have to alleviate well for dysmenorrhea to make individually With；See that careless oil can promote blood circulation, adjust the lipid material in blood, reduces the delay of fatty wall in the blood vessels, can exclude Cholesterol in the cell has been saved, has reduced triglyceride, blood cholesterol levels, the content of B- lipoprotein, therefore can effectively treat Because of diseases such as coronary ligation, atherosis and cerebral thrombosis caused by high cholesterol, hyperlipidemia；Evening primrose oil can promote fatty generation It thanks, moisturizes the skin, therefore cutaneous disorder phenomenon can be improved, treatment adjusts acne and blackspot caused by endocrine.For controlling It treats eczema and this kind of skin disease of dermatitis is also to have good effect；Evening primrose oil can strong muscles and bones, therefore evening primrose oil has and changes The effect of kind constitution；According to scientist research shows that evening primrose oil immune system can be provided needed for nutrition so that immune system Can be with normal operating, therefore evening primrose oil plays the role of good pre- anti-cancer.
Wild chrysanthemum: chrysanthemum is composite family herbaceos perennial, is one of parts of generic medicinal plants of Chinese tradition, mainly with head Inflorescence hyoscine.It is recorded according to ancient books, chrysanthemum sweet-bitter flavor, cold nature；There is relieve heat heat-clearing, clear liver and improve vision and the effects of detoxicating, relieving inflammation. It is puckery to dry, hyperactivity of fire, mesh, or the limbs pain as caused by wind, cold, wet, numb disease have certain curative effect.Cure mainly flu Wind-heat, headache etc..There is preventive and therapeutic effect to dizziness, headache, tinnitus.
Radix Angelicae Sinensis: blood-nourishing and blood: this product blood-nourishing and can have with blood, bowl spares, there is benefit in row, the gas medicine in sincere blood, also Panacea in blood is suitable for each benefit caused by the deficiency of blood.Syndrome.1. help painstaking effort, for the deficienty of the heart blood caused by a variety of causes, disease See palpitation and severe palpitation, insomnia and dreamful sleep, dizziness amnesia, colourless is simple and unadorned, and tongue lip color is light etc., with the special bushing blood of Radix Angelicae Sinensis, gains in depth of comprehension blood is supported, all diseases From removing, generally multi-purpose danggui buxue decoction can be with the medicines adapted such as radix rehmanniae preparata, Radix Paeoniae Alba, donkey-hide gelatin, Caulis Spatholobi.2. tonifying liver blood is used for liver blood deficiency Card, mostly because excessive blood loss or prolonged illness loss or it is weakness of the spleen and the stomach, change that member is insufficient or kidney channel loss, essence do not change blood symptoms include colourless without China, onyx dry up thin and brittle, and lip and nail color is light, dizziness ear, and night sleeps dreaminess, blurred vision dim eyesight, married woman's menstrual flow little or no amenorrhea etc., can be with The medicines such as Radix Paeoniae Alba, radix rehmanniae preparata, fructus lycii, mulberry fruit are the same as use.Tonifying blood and regulating menstruation.Promoting blood circulation and stopping pain.Relax bowel and defecation.
Lanolin: lanolin is attached to a kind of secretion grease on wool, is faint yellow or brown color soft paste； There is stickiness and satiny；Smelly faint and special, lanolin can be such that main ingredient is absorbed by mucous membrane and skin rapidly, have adhesive force, property is steady It is fixed, and can absorb water, it is not easy rancid.
The present invention, by continuously improving formula, develops novel couplant, especially spine on a large amount of practical basis The addition of beans, rheum officinale, styrax, Herba Lycopodii, borneol, menthol, evening primrose oil and lanolin has the effect of unexpected.
The present invention provides the following technical solutions:
The present invention provides a kind of Ultrasonography novel couplant, the group ingredient including following weight percent: chitin 1~ 3%, carbomer 4~4.5%, alginate 1.5~2%, polyethylene glycol 1~2%, alkyl-glucoside 1.5~2%, ethyl alcohol 3 ~4%, honeysuckle 2.5~3%, asparagus juice 2~3%, kuh-seng 0.5~1%, whin 2~2.5%, rheum officinale 1~1.5% rests in peace Perfume 0.5~1.5%, Herba Lycopodii 1.5~2.5%, radix scutellariae 2~2.5%, Radix Glycyrrhizae 1~1.5%, borneol 1~1.5%, menthol 0.5~1%, evening primrose oil 1~1.5%, lanolin 2~2.5%, wild chrysanthemum 0.5-1%, Radix Angelicae Sinensis 0.5-1%, deionized water 69.5~75%.
It as a preferred technical solution of the present invention, is made of following parts by weight: chitin 1%, carbomer 4%, sea Alginates 1.5%, polyethylene glycol 1%, alkyl-glucoside 1.5%, ethyl alcohol 3%, honeysuckle 2.5%, asparagus juice 2%, kuh-seng 0.5%, whin 2%, rheum officinale 1%, styrax 0.5%, Herba Lycopodii 1.5%, radix scutellariae 2%, Radix Glycyrrhizae 1%, borneol 1%, menthol 0.5%, evening primrose oil 1%, lanolin 2%, wild chrysanthemum 0.5%, Radix Angelicae Sinensis 0.5%, deionized water 69.5%.
As a preferred technical solution of the present invention, the alginate is sodium alginate, any in sodium alginate It is a kind of.
As a preferred technical solution of the present invention, which is characterized in that the preparation method is as follows:
Step 1: prepare Chinese medicine: honeysuckle, kuh-seng, whin, rheum officinale, styrax, Herba Lycopodii, radix scutellariae, Radix Glycyrrhizae, borneol, Menthol, evening primrose oil, wild chrysanthemum, Radix Angelicae Sinensis；
Step 2: cleaning: by honeysuckle, kuh-seng, whin, rheum officinale, styrax, Herba Lycopodii, radix scutellariae, Radix Glycyrrhizae, borneol, peppermint Brain, evening primrose oil, wild chrysanthemum, Radix Angelicae Sinensis clear water washes clean, and dry；
Step 3: it weighs: by honeysuckle, kuh-seng, whin, rheum officinale, styrax, Herba Lycopodii, radix scutellariae, Radix Glycyrrhizae, borneol, peppermint Above-mentioned raw materials are weighed by brain, evening primrose oil, wild chrysanthemum, Radix Angelicae Sinensis according to weight；
Step 4: milling: the raw material in the step 3 being put into grinder and is ground, and is crossed 230 meshes, is obtained mixed powder End is spare；
Step 5: asparagus juice production: fresh aloe is cleaned up, ultraviolet disinfection sterilization, is removed the peel again, crushing is subsequently placed in It is crushed in machine, reuses 100 mesh screens and be filtered, until aloe all passes through sieve, then carried out high speed centrifugation, collect and close And supernatant is asparagus juice；
Step 6: heating: deionized water is put into container and is heated, water temperature is to 65 to 70 DEG C；
Step 7: polyethylene glycol: being added stirring and dissolving 1h or more in the deionized water for going the step 6 heating by mixing, Until being all dissolved as solution, mixed liquor A is obtained；
Step 8: chitin, alkyl-glucoside, second secondary mixing: are added in step 7 mixed liquor A obtained Mixed-powder made from alcohol, lanolin and the step 4, and heat, and continue to stir 2h or more, mixed liquid B is obtained, and It heats maximum temperature and is no more than 50 DEG C；
Step 9: final mixing: in the step 5 that corresponding parts by weight are added in step 8 mixed liquid B obtained Asparagus juice, carbomer and alginate obtained stir 30~60min, obtain mixture C；
Step 10: adjust: in step 9 mixed liquor C obtained using pH adjusting agent adjust mixture C pH value to 6.5~7.5, it then transfers in homogenizer and carries out homogeneous to get Ultrasonography novel couplant.
As a preferred technical solution of the present invention, the grinder is conventional equipment, and the pulverizer is conventional sets It is standby.
As a preferred technical solution of the present invention, the pH adjusting agent is the aqueous solution of sodium hydroxide or, the hydrogen The mass concentration of sodium hydroxide is 3%~5% in aqueous solution of sodium oxide.
As a preferred technical solution of the present invention, the pressure of the homogeneous is 20~40MPa, and the temperature of homogeneous is 10 ~30 DEG C.
The beneficial effects obtained by the present invention are as follows being: Ultrasonography novel couplant of the invention has significantly by whin Clearing heat and detoxicating effect, can various internal haemorrhage symptoms intracorporal for people have good curative effect；Rheum officinale has row hemostasis Effect；The promoting flow of qi and blood circulation that styrax has, the effect of relieving the pain；Herba Lycopodii is for treating lumbar muscle strain, traumatic injury；The function of radix scutellariae The effect of effect includes heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis；The effect of Radix Glycyrrhizae include: for the heart qi deficiency, palpitation and severe palpitation, knotted pulse, And deficiency of spleen-QI and stomach-QI, while there are also anti-inflammatory, anti-allergic effects for Radix Glycyrrhizae, can protect the throat and tunica mucosa tracheae of inflammation；Contained by Radix Glycyrrhizae Hypo acid can block the effect of Induced by Carcinogen tumour growth；Include: antibacterial anti-inflammatory by the effect of borneol, has powerful antibacterial Effect, liquid oedema can be excluded, play the role of anti-inflammatory, can inducing resuscitation of having one's ideas straightened out, removing nebula for improving eyesight；One kind as obtained in peppermint The cyclic alcohol of saturation forms.With dispelling wind, the effect of heat-clearing, removing toxic substances；Evening primrose oil can promote blood circulation, and evening primrose oil can promote Entering fat fat metabolism moisturizes the skin, therefore can improve cutaneous disorder phenomenon.Wild chrysanthemum has relieve heat heat-clearing, reconciliation of clearing liver and improving vision The effects of malicious anti-inflammatory；Radix Angelicae Sinensis blood-nourishing and can have with blood, bowl spares, have benefit in row；It can make main ingredient rapidly by mucous membrane and skin It absorbs, there is adhesive force, property is stablized, and can absorb water, and is not easy rancid, can preferably protect skin；Plurality of raw materials is mixed and is taken Match, scientific composition, each raw material has complementary advantages, and using its mutual collaboration or resistant function, plays greasy skin, promoting blood circulationization The stasis of blood, inhibiting bacteria and diminishing inflammation, anti-corrosion be antipruritic, myogenic sore unique curative effect, and the moisturizings skin care ingredients such as aloe are added, reduce to skin The stimulation of skin, nourishes rough skin are non-stimulated that there is high-effective disinfecting to sterilize, is safe and non-toxic, without hypersensitive, nonirritant spy Property, it can avoid the cross-infection of clinically ultrasonic examination, can effectively kill various bacteriums etc., there is broad spectrum activity, bactericidal effect is aobvious It writes.
Specific embodiment
Embodiment 1
The present invention provides a kind of Ultrasonography novel couplant, including following parts by weight composition: chitin 1%, carbomer 4%, alginate 1.5%, polyethylene glycol 1%, alkyl-glucoside 1.5%, ethyl alcohol 3%, honeysuckle 2.5%, asparagus juice 2%, kuh-seng 0.5%, whin 2%, rheum officinale 1%, styrax 0.5%, Herba Lycopodii 1.5%, radix scutellariae 2%, Radix Glycyrrhizae 1%, borneol 1%, menthol 0.5%, evening primrose oil 1%, lanolin 2%, wild chrysanthemum 0.5%, Radix Angelicae Sinensis 0.5%, deionized water 69.5%.
The preparation method is as follows:
Step 1: prepare Chinese medicine: honeysuckle, kuh-seng, whin, rheum officinale, styrax, Herba Lycopodii, radix scutellariae, Radix Glycyrrhizae, borneol, Menthol, evening primrose oil, wild chrysanthemum, Radix Angelicae Sinensis；
Step 2: cleaning: by honeysuckle, kuh-seng, whin, rheum officinale, styrax, Herba Lycopodii, radix scutellariae, Radix Glycyrrhizae, borneol, peppermint Brain, evening primrose oil, wild chrysanthemum, Radix Angelicae Sinensis clear water washes clean, and dry；
Step 3: it weighs: by honeysuckle, kuh-seng, whin, rheum officinale, styrax, Herba Lycopodii, radix scutellariae, Radix Glycyrrhizae, borneol, peppermint Above-mentioned raw materials are weighed by brain, evening primrose oil, wild chrysanthemum, Radix Angelicae Sinensis according to weight；
Step 4: milling: the raw material in the step 3 being put into grinder and is ground, and is crossed 230 meshes, is obtained mixed powder End is spare；
Step 5: asparagus juice production: fresh aloe is cleaned up, ultraviolet disinfection sterilization, is removed the peel again, crushing is subsequently placed in It is crushed in machine, reuses 100 mesh screens and be filtered, until aloe all passes through sieve, then carried out high speed centrifugation, collect and close And supernatant is asparagus juice；
Step 6: heating: deionized water is put into container and is heated, water temperature is to 65 to 70 DEG C；
Step 7: polyethylene glycol: being added stirring and dissolving 1h or more in the deionized water for going the step 6 heating by mixing, Until being all dissolved as solution, mixed liquor A is obtained；
Step 8: chitin, alkyl-glucoside, second secondary mixing: are added in step 7 mixed liquor A obtained Mixed-powder made from alcohol, lanolin and the step 4, and heat, and continue to stir 2h or more, mixed liquid B is obtained, and It heats maximum temperature and is no more than 50 DEG C；
Step 9: final mixing: in the step 5 that corresponding parts by weight are added in step 8 mixed liquid B obtained Asparagus juice, carbomer and alginate obtained stir 30~60min, obtain mixture C；
Step 10: adjust: in step 9 mixed liquor C obtained using pH adjusting agent adjust mixture C pH value to 6.5~7.5, it then transfers in homogenizer and carries out homogeneous to get Ultrasonography novel couplant.
Comparative example 1
The present invention provides a kind of Ultrasonography novel couplant, including following parts by weight composition: chitin 1%, carbomer 4%, alginate 1.5%, polyethylene glycol 1%, alkyl-glucoside 1.5%, ethyl alcohol 3%, honeysuckle 2.5%, asparagus juice 3.5%, kuh-seng 0.5%, whin 2%, rheum officinale 1%, radix scutellariae 2%, Radix Glycyrrhizae 1%, evening primrose oil 1%, lanolin 2%, wild chrysanthemum 1%, Radix Angelicae Sinensis 2%, deionized water 69.5%.
The preparation method is as follows:
Step 1: prepare Chinese medicine: honeysuckle, kuh-seng, whin, rheum officinale, radix scutellariae, Radix Glycyrrhizae, evening primrose oil, wild chrysanthemum, when Return；
Step 2: cleaning: honeysuckle, kuh-seng, whin, rheum officinale, radix scutellariae, Radix Glycyrrhizae, evening primrose oil, wild chrysanthemum, Radix Angelicae Sinensis are used Clear water washes clean, and dry；
Step 3: it weighs: honeysuckle, kuh-seng, whin, rheum officinale, radix scutellariae, Radix Glycyrrhizae, evening primrose oil, wild chrysanthemum, Radix Angelicae Sinensis is pressed Above-mentioned raw materials are weighed according to weight；
Step 4: milling: the raw material in the step 3 being put into grinder and is ground, and is crossed 200 meshes, is obtained mixed powder End is spare；
Step 5: asparagus juice production: fresh aloe is cleaned up, ultraviolet disinfection sterilization, is removed the peel again, crushing is subsequently placed in It is crushed in machine, reuses 100 mesh screens and be filtered, until aloe all passes through sieve, then carried out high speed centrifugation, collect and close And supernatant is asparagus juice；
Step 6: heating: deionized water is put into container and is heated, water temperature is to 50 DEG C；
Step 7: mixing: by polyethylene glycol be added in the deionized water for going the step 6 heating stirring and dissolving 30min with On, until being all dissolved as solution, obtain mixed liquor A；
Step 8: chitin, alkyl-glucoside, second secondary mixing: are added in step 7 mixed liquor A obtained Mixed-powder made from alcohol, lanolin and the step 4, and heat, and continue to stir 1h or more, mixed liquid B is obtained, and It heats maximum temperature and is no more than 40 DEG C；
Step 9: final mixing: in the step 5 that corresponding parts by weight are added in step 8 mixed liquid B obtained Asparagus juice, carbomer and alginate obtained stir 30~60min, obtain mixture C；
Step 10: adjust: in step 9 mixed liquor C obtained using pH adjusting agent adjust mixture C pH value to 6.5~7.5, it then transfers in homogenizer and carries out homogeneous to get Ultrasonography novel couplant.
Comparative example 2
The present invention provides a kind of Ultrasonography novel couplant, including following parts by weight composition: chitin 1%, carbomer 4%, alginate 1.5%, polyethylene glycol 1%, alkyl-glucoside 1.5%, ethyl alcohol 3%, honeysuckle 2.5%, kuh-seng 0.5%, whin 2%, styrax 0.5%, Herba Lycopodii 1.5%, Radix Glycyrrhizae 1%, borneol 1%, menthol 0.5%, evening primrose oil 1%, wild chrysanthemum 0.5%, Radix Angelicae Sinensis 0.5%, deionized water 69.5%.
The preparation method is as follows:
Step 1: prepare Chinese medicine: honeysuckle, kuh-seng, whin, styrax, Herba Lycopodii, Radix Glycyrrhizae, borneol, menthol, the moon See careless oil, wild chrysanthemum, Radix Angelicae Sinensis；
Step 2: cleaning: by honeysuckle, kuh-seng, whin, styrax, Herba Lycopodii, Radix Glycyrrhizae, borneol, menthol, oenothera biennis Oil, wild chrysanthemum, Radix Angelicae Sinensis clear water washes clean, and dry；
Step 3: it weighs: by honeysuckle, kuh-seng, whin, styrax, Herba Lycopodii, Radix Glycyrrhizae, borneol, menthol, oenothera biennis Above-mentioned raw materials are weighed by oil, wild chrysanthemum, Radix Angelicae Sinensis according to weight；
Step 4: milling: the raw material in the step 3 being put into grinder and is ground, and is crossed 230 meshes, is obtained mixed powder End is spare；
Step 5: heating: deionized water is put into container and is heated, water temperature is to 670 DEG C；
Step 6: polyethylene glycol: being added stirring and dissolving 1h or more in the deionized water for going the step 6 heating by mixing, Until being all dissolved as solution, mixed liquor A is obtained；
Step 7: chitin, alkyl-glucoside, ethyl alcohol secondary mixing: are added in step 7 mixed liquor A obtained And mixed-powder made from the step 4, and heat, and continue to stir 1h or more, mixed liquid B is obtained, and heat the highest temperature Degree is no more than 50 DEG C；
Step 8: carbomer and the seaweed of corresponding parts by weight final mixing: are added in step 8 mixed liquid B obtained Hydrochlorate stirs 30~60min, obtains mixture C；
Step 9: adjust: in step 9 mixed liquor C obtained using pH adjusting agent adjust mixture C pH value to 6.5~7.5, it then transfers in homogenizer and carries out homogeneous to get Ultrasonography novel couplant.
Clinical data: case selection: selection 100 clinical observations of Ultrasonography patient, patient are randomly divided into two groups, experimental group 5 people, age 20-40, average age 35 years old, 50 people of control group, age 20-40, average age 35 years old.
When carrying out Ultrasonography treatment, 50 people of experimental group uses the Ultrasonography novel couplant of the embodiment of the present invention 1；Control group 50 people use the novel couplant of comparative example 2 and 3, comparative example 1:25 people；Comparative example 2:25 people.
Dependence test is carried out according to the traditional test methods of this field to above embodiments and comparative example, test result is such as Shown in following table；
By upper table it is found that the using effect of Ultrasonography novel couplant provided by the invention is apparently higher than control group, and Thimerosal of the invention is non-stimulated and nontoxic, and use is safe, meets the application requirement of medical and health industry.
Finally, it should be noted that the foregoing is only a preferred embodiment of the present invention, it is not intended to restrict the invention, Although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art, still may be used To modify the technical solutions described in the foregoing embodiments or equivalent replacement of some of the technical features. All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in of the invention Within protection scope.

Claims (7)

1. a kind of Ultrasonography novel couplant, which is characterized in that the group ingredient including following weight percent: chitin 1~ 3%, carbomer 4~4.5%, alginate 1.5~2%, polyethylene glycol 1~2%, alkyl-glucoside 1.5~2%, ethyl alcohol 3 ~4%, honeysuckle 2.5~3%, asparagus juice 2~3%, kuh-seng 0.5~1%, whin 2~2.5%, rheum officinale 1~1.5% rests in peace Perfume 0.5~1.5%, Herba Lycopodii 1.5~2.5%, radix scutellariae 2~2.5%, Radix Glycyrrhizae 1~1.5%, borneol 1~1.5%, menthol 0.5~1%, evening primrose oil 1~1.5%, lanolin 2~2.5%, wild chrysanthemum 0.5-1%, Radix Angelicae Sinensis 0.5-1%, deionized water 69.5~75%.
2. a kind of Ultrasonography novel couplant according to claim 1, which is characterized in that be made of following parts by weight: first Shell element 1%, carbomer 4%, alginate 1.5%, polyethylene glycol 1%, alkyl-glucoside 1.5%, ethyl alcohol 3%, honeysuckle 2.5%, asparagus juice 2%, kuh-seng 0.5%, whin 2%, rheum officinale 1%, styrax 0.5%, Herba Lycopodii 1.5%, radix scutellariae 2% is sweet Grass 1%, borneol 1%, menthol 0.5%, evening primrose oil 1%, lanolin 2%, wild chrysanthemum 0.5%, Radix Angelicae Sinensis 0.5%, deionization Water 69.5%.
3. a kind of Ultrasonography novel couplant according to claim 1, which is characterized in that the alginate is alginic acid Any one in sodium, sodium alginate.
4. a kind of Ultrasonography novel couplant according to claim 1, which is characterized in that the preparation method is as follows:
Step 1: prepare Chinese medicine: honeysuckle, kuh-seng, whin, rheum officinale, styrax, Herba Lycopodii, radix scutellariae, Radix Glycyrrhizae, borneol, peppermint Brain, evening primrose oil, wild chrysanthemum, Radix Angelicae Sinensis；
Step 2: cleaning: by honeysuckle, kuh-seng, whin, rheum officinale, styrax, Herba Lycopodii, radix scutellariae, Radix Glycyrrhizae, borneol, menthol, Evening primrose oil, wild chrysanthemum, Radix Angelicae Sinensis clear water washes clean, and dry；
Step 3: weigh: by honeysuckle, kuh-seng, whin, rheum officinale, styrax, Herba Lycopodii, radix scutellariae, Radix Glycyrrhizae, borneol, menthol, Above-mentioned raw materials are weighed by evening primrose oil, wild chrysanthemum, Radix Angelicae Sinensis according to weight；
Step 4: milling: the raw material in the step 3 being put into grinder and is ground, and crosses 230 meshes, it is standby to obtain mixed-powder With；
Step 5: asparagus juice production: fresh aloe is cleaned up, ultraviolet disinfection sterilization, is removed the peel again, is subsequently placed in pulverizer It crushes, reuses 100 mesh screens and be filtered, until aloe all passes through sieve, then carry out high speed centrifugation, collect and merge Clear liquid is asparagus juice；
Step 6: heating: deionized water is put into container and is heated, water temperature is to 65 to 70 DEG C；
Step 7: polyethylene glycol: being added stirring and dissolving 1h or more in the deionized water for going the step 6 heating by mixing, until It all is dissolved as solution, obtains mixed liquor A；
Step 8: chitin, alkyl-glucoside, ethyl alcohol, sheep secondary mixing: are added in step 7 mixed liquor A obtained Mixed-powder made from hair rouge and the step 4, and heat, and continue to stir 2h or more, mixed liquid B is obtained, and heat most High-temperature is no more than 50 DEG C；
Step 9: it final mixing: is made in the step 5 that corresponding parts by weight are added in step 8 mixed liquid B obtained Asparagus juice, carbomer and alginate, stir 30~60min, obtain mixture C；
Step 10: adjust: in step 9 mixed liquor C obtained using pH adjusting agent adjust the pH value of mixture C to 6.5~ 7.5, it then transfers in homogenizer and carries out homogeneous to get Ultrasonography novel couplant.
5. a kind of Ultrasonography novel couplant according to claim 4, which is characterized in that the grinder is conventional sets Standby, the pulverizer is conventional equipment.
6. a kind of Ultrasonography novel couplant according to claim 4, which is characterized in that the pH adjusting agent is hydroxide The aqueous solution of sodium is or, the mass concentration of sodium hydroxide is 3%~5% in the sodium hydrate aqueous solution.
7. a kind of Ultrasonography novel couplant according to claim 4, which is characterized in that the pressure of the homogeneous be 20~ 40MPa, the temperature of homogeneous are 10~30 DEG C.
CN201910047808.8A 2019-01-18 2019-01-18 A kind of Ultrasonography novel couplant Pending CN109529062A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101322869A (en) * 2007-06-14 2008-12-17 重庆融海超声医学工程研究中心有限公司 Retaining type ultrasonic treatment gun and ultrasonic beauty treatment equipment containing the treatment gun
CN103638535A (en) * 2013-12-04 2014-03-19 夏青 B ultrasound coupling agent containing traditional Chinese components
CN107753961A (en) * 2017-12-06 2018-03-06 青岛大学附属医院 A kind of Color Sonography ultrasonic coupling agent
CN108553654A (en) * 2018-05-04 2018-09-21 顾建文 A kind of B ultrasound couplant and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101322869A (en) * 2007-06-14 2008-12-17 重庆融海超声医学工程研究中心有限公司 Retaining type ultrasonic treatment gun and ultrasonic beauty treatment equipment containing the treatment gun
CN103638535A (en) * 2013-12-04 2014-03-19 夏青 B ultrasound coupling agent containing traditional Chinese components
CN107753961A (en) * 2017-12-06 2018-03-06 青岛大学附属医院 A kind of Color Sonography ultrasonic coupling agent
CN108553654A (en) * 2018-05-04 2018-09-21 顾建文 A kind of B ultrasound couplant and preparation method thereof

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