CN109475299A - 使用超声背向散射用于传感生理学状况的移植物 - Google Patents
使用超声背向散射用于传感生理学状况的移植物 Download PDFInfo
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- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
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- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0529—Electrodes for brain stimulation
- A61N1/0534—Electrodes for deep brain stimulation
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- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
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- A—HUMAN NECESSITIES
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- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112345116A (zh) * | 2020-12-01 | 2021-02-09 | 山东大学 | 一种基于后向散射能量的超声测温装置与方法 |
| CN115276658A (zh) * | 2022-07-07 | 2022-11-01 | 兰州科近泰基新技术有限责任公司 | 电荷频率转换电路、转换方法及粒子治疗剂量监测装置 |
| CN116541896A (zh) * | 2023-07-06 | 2023-08-04 | 北京领创医谷科技发展有限责任公司 | 一种植入设备识别电路、植入设备及读取设备 |
| EP4258998A4 (en) * | 2020-12-08 | 2025-01-01 | Geegah LLC | IMAGING AND DETECTION OF A THIN FILM WITH HIGH FREQUENCY ULTRASONIC TRANSDUCERS |
Families Citing this family (137)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3581105T3 (pl) | 2010-05-08 | 2022-11-28 | The Regents Of The University Of California | Urządzenie do wczesnego wykrywania owrzodzenia przez skanowanie uwodnienia podnaskórkowego |
| US12465324B2 (en) | 2015-02-12 | 2025-11-11 | Foundry Innovation & Research 1, Ltd. | Patient fluid management systems and methods employing integrated fluid status sensing |
| AU2016250527B2 (en) | 2015-04-24 | 2021-01-14 | Bruin Biometrics, Llc | Apparatus and methods for determining damaged tissue using sub-epidermal moisture measurements |
| US11043988B2 (en) | 2016-03-15 | 2021-06-22 | Verily Life Sciences LLP | Systems for providing wireless power to deep implanted devices |
| CA3029899A1 (en) | 2016-07-07 | 2018-01-11 | The Regents Of The University Of California | Implants using ultrasonic backscatter for detecting electrophysiological signals |
| CN110392550B (zh) * | 2016-07-25 | 2023-10-03 | 撒哈拉·凯瑟林·帕奇 | 用声波测量进行辐射束射程验证的系统和方法 |
| US11047979B2 (en) * | 2016-07-27 | 2021-06-29 | Sound Technology Inc. | Ultrasound transducer array |
| US11701018B2 (en) | 2016-08-11 | 2023-07-18 | Foundry Innovation & Research 1, Ltd. | Wireless resonant circuit and variable inductance vascular monitoring implants and anchoring structures therefore |
| EP3496606A1 (en) | 2016-08-11 | 2019-06-19 | Foundry Innovation & Research 1, Ltd. | Systems and methods for patient fluid management |
| US11206992B2 (en) | 2016-08-11 | 2021-12-28 | Foundry Innovation & Research 1, Ltd. | Wireless resonant circuit and variable inductance vascular monitoring implants and anchoring structures therefore |
| US11309744B2 (en) * | 2016-09-11 | 2022-04-19 | Verily Life Sciences Llc | Systems and methods for providing wireless power to deep implanted devices |
| WO2018125912A1 (en) * | 2016-12-28 | 2018-07-05 | The Trustees Of Columbia University In The City Of New York | An ultrasound phased array patch on flexible cmos and methods for fabricating thereof |
| CN110419115B (zh) * | 2017-01-10 | 2024-03-19 | 加利福尼亚大学董事会 | 可拉伸超声换能器器件 |
| NZ773584A (en) | 2017-02-03 | 2025-07-25 | Bbi Medical Innovations Llc | Measurement of susceptibility to diabetic foot ulcers |
| CA3042101C (en) | 2017-02-03 | 2024-04-09 | Bruin Biometrics, Llc | Measurement of edema |
| FI3515296T3 (fi) | 2017-02-03 | 2023-12-21 | Bbi Medical Innovations Llc | Kudoksen elinkelpoisuuden mittaus |
| US11083174B2 (en) * | 2017-03-24 | 2021-08-10 | Zalliant, LLC | Communication assembly for monitoring biological data of animals |
| WO2018194616A1 (en) * | 2017-04-20 | 2018-10-25 | Hewlett-Packard Development Company, L.P. | Calibrating communication lines |
| US10664591B2 (en) | 2017-05-11 | 2020-05-26 | Microsoft Technology Licensing, Llc | Enclave pools |
| US10833858B2 (en) | 2017-05-11 | 2020-11-10 | Microsoft Technology Licensing, Llc | Secure cryptlet tunnel |
| US10747905B2 (en) | 2017-05-11 | 2020-08-18 | Microsoft Technology Licensing, Llc | Enclave ring and pair topologies |
| US10740455B2 (en) | 2017-05-11 | 2020-08-11 | Microsoft Technology Licensing, Llc | Encave pool management |
| US10528722B2 (en) | 2017-05-11 | 2020-01-07 | Microsoft Technology Licensing, Llc | Enclave pool shared key |
| US11944495B2 (en) | 2017-05-31 | 2024-04-02 | Foundry Innovation & Research 1, Ltd. | Implantable ultrasonic vascular sensor |
| US11779238B2 (en) | 2017-05-31 | 2023-10-10 | Foundry Innovation & Research 1, Ltd. | Implantable sensors for vascular monitoring |
| US10238288B2 (en) * | 2017-06-15 | 2019-03-26 | Microsoft Technology Licensing, Llc | Direct frequency modulating radio-frequency sensors |
| US11641168B2 (en) * | 2017-07-17 | 2023-05-02 | Georgia Tech Research Corporation | Parametric resonator for electrical transduction |
| US11547347B2 (en) * | 2017-10-06 | 2023-01-10 | Massachusetts Institute Of Technology | Flexible piezoelectric devices for gastrointestinal motility sensing |
| MX2020005138A (es) | 2017-11-16 | 2020-08-17 | Bruin Biometrics Llc | Tratamiento estrategico de ulceras por presion por el uso de valores humedad subepidermica. |
| GB201800820D0 (en) * | 2018-01-18 | 2018-03-07 | Univ Oslo Hf | Medical implant with wireless communication |
| CN111741794B (zh) * | 2018-01-24 | 2023-07-28 | 新加坡国立大学 | 光动力疗法系统及其发射器和可植入照明装置 |
| US11193836B2 (en) | 2018-02-01 | 2021-12-07 | Electric Power Research Institute, Inc. | Apparatus having a semiconductor strain gage encased within ceramic material for measuring strain and methods for making and using same |
| GB2584226B (en) | 2018-02-09 | 2022-06-22 | Bruin Biometrics Llc | Detection of tissue damage |
| DE102018204949A1 (de) * | 2018-03-30 | 2019-10-02 | Bernhard Clasbrummel | Implantat und Verfahren zur Diagnose und/oder Behandlung entzündlicher Gewebezustände |
| CN118354099A (zh) * | 2018-04-02 | 2024-07-16 | 寰发股份有限公司 | 用于视频编解码系统中的子块运动补偿的视频处理方法和装置 |
| CA3097139A1 (en) * | 2018-04-19 | 2019-10-24 | Jose M. Carmena | Implants using ultrasonic communication for modulating splenic nerve activity |
| CN112272575B (zh) * | 2018-04-19 | 2024-05-17 | 艾奧塔生物科技公司 | 使用用于神经感测和刺激的超声通信的植入物 |
| EP3556279B1 (en) * | 2018-04-19 | 2024-11-06 | Cochlear Limited | Near infrared light in hearing aid appliances |
| JP7410935B2 (ja) | 2018-05-24 | 2024-01-10 | ザ リサーチ ファウンデーション フォー ザ ステイト ユニバーシティー オブ ニューヨーク | 容量性センサ |
| DE102018209449A1 (de) * | 2018-06-13 | 2019-12-19 | Neuroloop GmbH | Medizinisches Implantat, Anordnung zum Implantieren des medizinischen Implantats sowie Anordnung zum Erfassen eines intrakorporalen Bewegungsmusters mit dem medizinischen Implantat |
| US11266840B2 (en) | 2018-06-27 | 2022-03-08 | Arizona Board Of Regents On Behalf Of Arizona State University | Wireless cardiac pace making |
| US11464964B2 (en) * | 2018-08-03 | 2022-10-11 | Brown University | Neural interrogation platform |
| US11134858B1 (en) | 2018-08-04 | 2021-10-05 | PhonoFlow Medical, LLC | Systems, apparatuses, and methods for locating blood flow turbulence in the cardiovascular system |
| US11167375B2 (en) | 2018-08-10 | 2021-11-09 | The Research Foundation For The State University Of New York | Additive manufacturing processes and additively manufactured products |
| PL3843830T3 (pl) | 2018-08-29 | 2024-08-12 | Iota Biosciences, Inc. | Wszczepialne urządzenie do neuromodulacji w zamkniętej pętli |
| CN109381786B (zh) * | 2018-09-10 | 2023-10-31 | 清华大学 | 用于检测植入式医疗仪器交叉电脉冲性能的系统 |
| US12059582B2 (en) | 2018-10-11 | 2024-08-13 | The Penn State Research Foundation | Implantable dual mode ultrasonic device |
| DK4283799T3 (da) | 2018-10-11 | 2025-04-22 | Bruin Biometrics Llc | Indretning med engangselement |
| JP2022502119A (ja) | 2018-10-15 | 2022-01-11 | メイザー ロボティックス リミテッド | 汎用マルチアームロボット外科用システム |
| JP6942687B2 (ja) * | 2018-11-07 | 2021-09-29 | 古河電気工業株式会社 | 医療器具及び医療器具確認システム |
| WO2020117967A1 (en) * | 2018-12-06 | 2020-06-11 | Iota Biosciences, Inc. | Device networks for modulating neural activity |
| PT3906091T (pt) * | 2019-01-04 | 2024-08-13 | Iota Biosciences Inc | Protocolo baseado em ultrassom para operação de um dispositivo implantável |
| JP7520847B2 (ja) * | 2019-01-04 | 2024-07-23 | イオタ バイオサイエンシズ, インコーポレイテッド | 超音波を使用して電力を供給するインプランタブルデバイスの電力制御 |
| CN113613708B (zh) * | 2019-01-23 | 2025-11-07 | 香港理工大学 | 可植入装置上使用一个或多个超声换能器的瞄准能量传输方法 |
| CN116966428A (zh) * | 2019-03-12 | 2023-10-31 | 脉冲动力(北京)医疗科技有限公司 | 用于医疗装置的安全短距离通信链路 |
| US11696713B2 (en) | 2019-03-15 | 2023-07-11 | Arizona Board Of Regents On Behalf Of Arizona State University | Contour electrocorticography (ECoG) array |
| US11428588B2 (en) | 2019-03-28 | 2022-08-30 | Arizona Board Of Regents On Behalf Of Arizona State University | Fully-passive pressure sensors and methods for their use |
| US12059572B2 (en) * | 2019-04-25 | 2024-08-13 | Medtronic, Inc. | Implantable ultrasonic device |
| JP7393881B2 (ja) * | 2019-06-17 | 2023-12-07 | 株式会社アイシン | ソナーユニット |
| CA3144005A1 (en) * | 2019-07-10 | 2021-01-14 | Ulink Labs, Inc. | Systems, devices, and methods for establishing a wireless link |
| US20210007602A1 (en) * | 2019-07-12 | 2021-01-14 | Neuralink Corp. | Brain implant with subcutaneous wireless relay and external wearable communication and power device |
| WO2021011902A1 (en) * | 2019-07-17 | 2021-01-21 | NXgenPort, L.L.C. | Implantable venous access port with remote physiological monitoring capabilities |
| CN110368033B (zh) * | 2019-08-30 | 2024-12-31 | 深圳开立生物医疗科技股份有限公司 | 一种血管内超声诊断系统 |
| EP3789125A1 (de) * | 2019-09-03 | 2021-03-10 | BIOTRONIK SE & Co. KG | Implantierbarer ultraschallwandler |
| EP3788948A1 (en) * | 2019-09-04 | 2021-03-10 | Universitat Pompeu Fabra | Implantable electronic sensing system for measuring and monitoring medical parameters |
| CN110801223B (zh) * | 2019-09-30 | 2021-09-14 | 昆明理工大学 | 一种无线脑深部神经接口系统 |
| CN114731199B (zh) * | 2019-10-16 | 2024-04-30 | Wyss生物和神经工程中心 | 可植入系统的光传输 |
| IL292039A (en) * | 2019-10-17 | 2022-06-01 | Iota Biosciences Inc | Helical nerve cuff and related implantable device |
| AU2020367447A1 (en) | 2019-10-17 | 2022-04-21 | Iota Biosciences, Inc. | Devices and methods for modulating immune system activity in a cancer patient and treating cancer |
| US20220401031A1 (en) * | 2019-11-11 | 2022-12-22 | National University Of Singapore | Wirelessly triggered device |
| CN110769610A (zh) * | 2019-11-27 | 2020-02-07 | 华中科技大学 | 一种表皮电子器件和多模态表皮电子传感器的制备方法 |
| US20210196989A1 (en) * | 2019-12-13 | 2021-07-01 | Northeastern University | Implantable Bio-Heating System Based on Piezoelectric Micromachined Ultrasonic Transducers |
| US11320453B2 (en) | 2019-12-30 | 2022-05-03 | Texas Instruments Incorporated | Aging compensation of a ferroelectric piezoelectric shock sensor |
| WO2021138505A1 (en) * | 2019-12-30 | 2021-07-08 | The Regents Of The University Of California | Multi-gas detection with cs-fet arrays for food quality assessment |
| US20210251488A1 (en) * | 2020-02-13 | 2021-08-19 | Cardiac Pacemakers. Inc. | Hermetically sealed implantable medical device and method of formation |
| US20230095948A1 (en) * | 2020-02-19 | 2023-03-30 | The Regents Of The University Of California | A deep tissue ultrasonic implantable luminescence oxygen sensor |
| WO2021168163A1 (en) * | 2020-02-19 | 2021-08-26 | Chan Zuckerberg Biohub, Inc. | Anchor loss in millimeter-scale ultrasonic wireless implantable devices |
| US12408963B2 (en) | 2020-02-20 | 2025-09-09 | Canary Medical Switzerland Ag | Medical device for implanting in boney tissue and characterization of bone fractures |
| FR3107651B1 (fr) * | 2020-03-02 | 2022-03-11 | Carthera | Procede et systeme pour la detection d’un defaut de couplage acoustique entre un dispositif ultrasonore et un tissu a traiter |
| TWI888516B (zh) * | 2020-03-25 | 2025-07-01 | 美商感應學公司 | 可植入設備、製造可植入設備之方法、及可植入設備之耦合器 |
| US20210313028A1 (en) * | 2020-04-01 | 2021-10-07 | Medtronic, Inc. | Physiological monitoring system |
| JP7562109B2 (ja) * | 2020-04-13 | 2024-10-07 | 国立大学法人東海国立大学機構 | 神経刺激システムおよび神経刺激方法 |
| US11678112B2 (en) | 2020-04-30 | 2023-06-13 | Massachusetts Institute Of Technology | Underwater transducer for wide-band communication |
| US12453496B2 (en) * | 2020-06-02 | 2025-10-28 | University Of South Florida | Silicon carbide nanoparticles fibrous membrane for implantable glucose sensor integrated with chronoamperometric potentiostat |
| EP4195999A4 (en) * | 2020-08-11 | 2024-09-04 | Iota Biosciences, Inc. | Ultrasonic implant and system for measurement of intraocular pressure |
| WO2022040102A1 (en) * | 2020-08-17 | 2022-02-24 | Arizona Board Of Regents On Behalf Of The University Of Arizona | An implantable miniaturized and soft wireless sensing device to monitor tissue and bone deformation |
| CN111938794B (zh) * | 2020-08-20 | 2022-03-15 | 四川大学华西医院 | 基于应力自适应调节的智能化骨科外支架系统 |
| WO2022046770A1 (en) * | 2020-08-24 | 2022-03-03 | Iota Biosciences, Inc. | Tracking an implantable device powered using ultrasonic waves |
| ES3036333T3 (en) * | 2020-09-01 | 2025-09-17 | Univ Aarhus | Implantable micro device with high data rate back scattering |
| EP4208946A1 (en) | 2020-09-01 | 2023-07-12 | Aarhus Universitet | High impedance and compact neural sensor front-end |
| WO2022056549A1 (en) * | 2020-09-14 | 2022-03-17 | Jackson Nathan Morrow | Microfabricated ultrasound transducer array for neural stimulation |
| JP7450929B2 (ja) * | 2020-09-16 | 2024-03-18 | 学校法人東京電機大学 | 圧力測定システム、圧力測定方法、およびプログラム |
| CN112220494B (zh) * | 2020-09-25 | 2023-05-05 | 天津大学 | 一种基于脉冲重复频率的声电神经成像系统 |
| US12274525B2 (en) | 2020-09-29 | 2025-04-15 | Mazor Robotics Ltd. | Systems and methods for tracking anatomical motion |
| US12490908B2 (en) * | 2020-10-20 | 2025-12-09 | The Regents Of The University Of California | Integrated chemical/ultrasonic transducer sensor |
| CN112155597B (zh) * | 2020-10-21 | 2025-06-20 | 北京华科恒生医疗科技有限公司 | 超声同步电极、立体电极、超声传感器及其使用方法 |
| CN112357013B (zh) * | 2020-11-16 | 2021-10-15 | 广东桂荣永磁新材料科技有限公司 | 一种强磁打捞器 |
| IT202000029327A1 (it) * | 2020-12-01 | 2022-06-01 | Imedicals S R L | Metodo per la diagnosi del carcinoma renale mediante analisi di segnali ultrasonici ed immagini ecografiche |
| WO2022120765A1 (zh) * | 2020-12-10 | 2022-06-16 | 中国科学院深圳先进技术研究院 | 一种实时超声刺激电信号记录芯片及其制备方法 |
| CN112870562B (zh) * | 2021-01-06 | 2022-05-17 | 上海交通大学 | 一种植入式压电mems超声换能器及其制备方法 |
| CN112865116B (zh) * | 2021-01-11 | 2022-04-12 | 广西大学 | 一种平行联邦图神经网络的十三区图无功优化方法 |
| CN112741969A (zh) * | 2021-01-13 | 2021-05-04 | 蔡哲兴 | 可植入颅骨的超声波治疗装置 |
| US11504093B2 (en) * | 2021-01-22 | 2022-11-22 | Exo Imaging, Inc. | Equalization for matrix based line imagers for ultrasound imaging systems |
| EP4266991A4 (en) * | 2021-01-29 | 2025-01-01 | The Regents of University of California | IMPLANTABLE IMAGING DEVICES FOR IN VIVO IMAGING |
| GB202101374D0 (en) * | 2021-02-01 | 2021-03-17 | Sintef Tto As | Object imaging within structures |
| US12465441B2 (en) | 2021-02-01 | 2025-11-11 | Mazor Robotics Ltd. | Multi-arm robotic systems and methods for identifying a target |
| US11642075B2 (en) | 2021-02-03 | 2023-05-09 | Bruin Biometrics, Llc | Methods of treating deep and early-stage pressure induced tissue damage |
| CN115078531B (zh) * | 2021-03-15 | 2025-11-14 | 北京信泰智合科技发展有限公司 | 一种高频压电换能振元、高频超声探头和制备方法 |
| EP4340929A4 (en) * | 2021-05-17 | 2024-10-16 | The Trustees Of Columbia University In The City Of New York | DEVICES, SYSTEMS, METHODS AND COMPUTER-ACCESSIBLE MEDIUM FOR PROVIDING WIRELESS STENT-BASED INTERFACES TO THE NERVOUS SYSTEM |
| US20220378291A1 (en) * | 2021-06-01 | 2022-12-01 | Twenty Twenty Therapeutics Llc | Ultrasound Intraocular Pressure Sensor in Sclera or in Cornea |
| US12053330B2 (en) | 2021-06-23 | 2024-08-06 | Exo Imaging, Inc. | Systems and methods for testing MEMS arrays and associated ASICs |
| AU2022301200A1 (en) | 2021-06-29 | 2024-01-04 | Ulink Labs, Inc. | Systems, devices, and methods for establishing a wireless link in a heterogeneous medium |
| CN113676263B (zh) * | 2021-08-10 | 2022-12-16 | 华南理工大学 | 基于超声波反向散射的人体内通信装置及方法 |
| WO2023027200A1 (ko) * | 2021-08-23 | 2023-03-02 | 단국대학교 산학협력단 | 통신 네트워크, 이에 연결된 노드를 식별하는 방법 및 장치 |
| US12306165B2 (en) * | 2022-03-07 | 2025-05-20 | Hach Company | Probe system with detachable sensor probe that communicates wirelessly |
| CN119156788A (zh) * | 2022-03-23 | 2024-12-17 | 艾奧塔生物科技公司 | 调频通信 |
| CN116920278A (zh) * | 2022-04-01 | 2023-10-24 | 创领心律管理医疗器械(上海)有限公司 | 植入式心脏起搏器、程控装置以及心脏起搏系统 |
| GB202204823D0 (en) * | 2022-04-01 | 2022-05-18 | Sintef Tto As | Ultrasonic transducer housing |
| WO2023209142A1 (en) * | 2022-04-28 | 2023-11-02 | Institut National De La Sante Et De La Recherche Medicale | Ultrasound-based wireless battery-free implantable sensors comprising a solutiongated field-effect transistor |
| EP4525698A1 (en) * | 2022-05-20 | 2025-03-26 | Foundry Innovation & Research 1, Ltd. | Resonant circuit-based vascular monitors and related systems and methods |
| JP2023173685A (ja) * | 2022-05-26 | 2023-12-07 | 上海天馬微電子有限公司 | 超音波センサ装置及びその制御方法 |
| NL1044346B1 (en) | 2022-06-01 | 2023-12-12 | Roodenburg Michael | Reusable Pallet Tent |
| JP7756974B2 (ja) * | 2022-06-17 | 2025-10-21 | ウィリアム マーシュ ライス ユニバーシティ | 植え込み型デバイスとの無線通信のためのシステムおよび方法 |
| EP4561673A1 (en) | 2022-07-29 | 2025-06-04 | Foundry Innovation & Research 1, Ltd. | Multistranded conductors adapted to dynamic in vivo environments |
| US11886668B1 (en) * | 2022-10-07 | 2024-01-30 | Infineon Technologies Ag | Ultrasonic touch sensor with active feedback |
| WO2024097917A1 (en) * | 2022-11-04 | 2024-05-10 | Secondwave Systems, Inc. | Implantable neurostimulator device |
| DE102022129889B3 (de) * | 2022-11-11 | 2023-12-21 | Tdk Electronics Ag | Elektro-akustisches Multifunktionsmodul und elektro-akustisches Kommunikationssystem |
| WO2024138161A2 (en) * | 2022-12-23 | 2024-06-27 | Ulink Labs, Inc. | Systems, devices, and methods for exchanging wireless signals |
| CN116140174B (zh) * | 2023-01-03 | 2024-11-29 | 深圳高性能医疗器械国家研究院有限公司 | 微纳超声发生器件以及声穿孔基因转染系统 |
| CN116251016B (zh) * | 2023-05-10 | 2023-08-01 | 四川大学华西医院 | 一种用于治疗骨质疏松的治疗头装置 |
| WO2024263992A1 (en) * | 2023-06-21 | 2024-12-26 | The Board Of Trustees Of The Leland Stanford Junior University | Systems, devices, and methods for using focused ultrasonic energy to inhibit communication of peripheral sensory nerves |
| WO2025038973A1 (en) * | 2023-08-16 | 2025-02-20 | Nidus Holdings, Llc | Implantable energy devices and methods |
| TWI880418B (zh) * | 2023-10-30 | 2025-04-11 | 佳世達科技股份有限公司 | 超音波收發裝置及其控制方法 |
| TWI879220B (zh) * | 2023-11-09 | 2025-04-01 | 佳世達科技股份有限公司 | 超音波傳感器及其控制方法 |
| GB2639636A (en) * | 2024-03-20 | 2025-10-01 | Univ Newcastle | Ultrasound apparatus |
| CN118236624B (zh) * | 2024-04-16 | 2025-09-02 | 华中科技大学 | 一种基于超声驱动的无源植入式双相脑刺激器件 |
| TWI889557B (zh) * | 2024-09-27 | 2025-07-01 | 大陸商慶鼎精密電子(淮安)有限公司 | 生物可植入裝置及其製造方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140336474A1 (en) * | 2013-05-13 | 2014-11-13 | The Board Of Trustees Of The Leland Stanford Junior University | Hybrid communication system for implantable devices and ultra-low power sensors |
Family Cites Families (148)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1178612A (en) | 1914-01-26 | 1916-04-11 | Yawman & Erbe Mfg Co | Metallic-furniture casing. |
| US2830274A (en) | 1954-01-04 | 1958-04-08 | Gen Electric | Electromechanical transducer |
| JPS5149826Y2 (enExample) * | 1971-05-28 | 1976-12-01 | ||
| US5662109A (en) | 1990-12-14 | 1997-09-02 | Hutson; William H. | Method and system for multi-dimensional imaging and analysis for early detection of diseased tissue |
| DE4104359A1 (de) | 1991-02-13 | 1992-08-20 | Implex Gmbh | Ladesystem fuer implantierbare hoerhilfen und tinnitus-maskierer |
| US5833603A (en) | 1996-03-13 | 1998-11-10 | Lipomatrix, Inc. | Implantable biosensing transponder |
| US5749909A (en) | 1996-11-07 | 1998-05-12 | Sulzer Intermedics Inc. | Transcutaneous energy coupling using piezoelectric device |
| AU6667698A (en) | 1997-02-26 | 1998-09-18 | Alfred E. Mann Foundation For Scientific Research | Battery-powered patient implantable device |
| US6050943A (en) | 1997-10-14 | 2000-04-18 | Guided Therapy Systems, Inc. | Imaging, therapy, and temperature monitoring ultrasonic system |
| US6239724B1 (en) | 1997-12-30 | 2001-05-29 | Remon Medical Technologies, Ltd. | System and method for telemetrically providing intrabody spatial position |
| US6402689B1 (en) | 1998-09-30 | 2002-06-11 | Sicel Technologies, Inc. | Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors |
| US7575550B1 (en) | 1999-03-11 | 2009-08-18 | Biosense, Inc. | Position sensing based on ultrasound emission |
| US6170488B1 (en) | 1999-03-24 | 2001-01-09 | The B. F. Goodrich Company | Acoustic-based remotely interrogated diagnostic implant device and system |
| US6200265B1 (en) | 1999-04-16 | 2001-03-13 | Medtronic, Inc. | Peripheral memory patch and access method for use with an implantable medical device |
| US6725073B1 (en) | 1999-08-17 | 2004-04-20 | Board Of Regents, The University Of Texas System | Methods for noninvasive analyte sensing |
| US6216022B1 (en) | 2000-06-22 | 2001-04-10 | Biosafe Laboratories, Inc. | Implantable optical measurement device and method for using same |
| US6654638B1 (en) | 2000-04-06 | 2003-11-25 | Cardiac Pacemakers, Inc. | Ultrasonically activated electrodes |
| US7283874B2 (en) | 2000-10-16 | 2007-10-16 | Remon Medical Technologies Ltd. | Acoustically powered implantable stimulating device |
| US7024248B2 (en) | 2000-10-16 | 2006-04-04 | Remon Medical Technologies Ltd | Systems and methods for communicating with implantable devices |
| US7198603B2 (en) * | 2003-04-14 | 2007-04-03 | Remon Medical Technologies, Inc. | Apparatus and methods using acoustic telemetry for intrabody communications |
| US6628989B1 (en) | 2000-10-16 | 2003-09-30 | Remon Medical Technologies, Ltd. | Acoustic switch and apparatus and methods for using acoustic switches within a body |
| DE50201594D1 (de) | 2001-07-28 | 2004-12-23 | Aesculap Ag & Co Kg | Medizinisches implantatsystem |
| US7479112B2 (en) | 2003-08-26 | 2009-01-20 | Cardiac Pacemakers, Inc. | Acoustic physiological sensor |
| US20050075702A1 (en) | 2003-10-01 | 2005-04-07 | Medtronic, Inc. | Device and method for inhibiting release of pro-inflammatory mediator |
| US7418292B2 (en) | 2003-10-01 | 2008-08-26 | Medtronic, Inc. | Device and method for attenuating an immune response |
| WO2005051444A2 (en) | 2003-11-20 | 2005-06-09 | Angiotech International Ag | Soft tissue implants and anti-scarring agents |
| US20050249667A1 (en) | 2004-03-24 | 2005-11-10 | Tuszynski Jack A | Process for treating a biological organism |
| US20050215764A1 (en) | 2004-03-24 | 2005-09-29 | Tuszynski Jack A | Biological polymer with differently charged portions |
| KR101163254B1 (ko) | 2004-04-14 | 2012-07-09 | 타이코 일렉트로닉스 코포레이션 | 음향 터치 센서 |
| US7606621B2 (en) | 2004-12-21 | 2009-10-20 | Ebr Systems, Inc. | Implantable transducer devices |
| US8165696B2 (en) | 2005-02-25 | 2012-04-24 | Boston Scientific Neuromodulation Corporation | Multiple-pronged implantable stimulator and methods of making and using such a stimulator |
| US7542800B2 (en) | 2005-04-05 | 2009-06-02 | Cardiac Pacemakers, Inc. | Method and apparatus for synchronizing neural stimulation to cardiac cycles |
| US8634908B2 (en) | 2005-08-01 | 2014-01-21 | Ebr Systems, Inc. | Efficiently delivering acoustic stimulation energy to tissue |
| US8649876B2 (en) * | 2005-09-10 | 2014-02-11 | Artann Laboratories Inc. | Leadless system for deep brain stimulation using time reversal acoustics |
| US7616990B2 (en) | 2005-10-24 | 2009-11-10 | Cardiac Pacemakers, Inc. | Implantable and rechargeable neural stimulator |
| WO2007090159A1 (en) | 2006-01-31 | 2007-08-09 | Medtronic, Inc. | Implantable sensor |
| JP5098214B2 (ja) | 2006-04-28 | 2012-12-12 | 日産自動車株式会社 | 半導体装置およびその製造方法 |
| US7899542B2 (en) | 2006-06-20 | 2011-03-01 | Ebr Systems, Inc. | Systems and methods for implantable leadless spine stimulation |
| US8078283B2 (en) | 2006-06-20 | 2011-12-13 | Ebr Systems, Inc. | Systems and methods for implantable leadless bone stimulation |
| US7894904B2 (en) | 2006-06-20 | 2011-02-22 | Ebr Systems, Inc. | Systems and methods for implantable leadless brain stimulation |
| US7894907B2 (en) | 2006-06-20 | 2011-02-22 | Ebr Systems, Inc. | Systems and methods for implantable leadless nerve stimulation |
| US7899541B2 (en) | 2006-06-20 | 2011-03-01 | Ebr Systems, Inc. | Systems and methods for implantable leadless gastrointestinal tissue stimulation |
| US7757565B2 (en) | 2006-08-24 | 2010-07-20 | Board Of Trustees Operating Michigan State University | Self-powered sensor |
| US9135686B2 (en) | 2006-10-25 | 2015-09-15 | The Invention Science Fund I Llc | Distorting feature compensating |
| US11389171B2 (en) | 2006-11-21 | 2022-07-19 | David S. Goldsmith | Integrated system for the infixion and retrieval of implants |
| US11320588B1 (en) * | 2012-04-16 | 2022-05-03 | Mohammad A. Mazed | Super system on chip |
| US8718773B2 (en) | 2007-05-23 | 2014-05-06 | Ebr Systems, Inc. | Optimizing energy transmission in a leadless tissue stimulation system |
| WO2008156981A2 (en) | 2007-06-14 | 2008-12-24 | Cardiac Pacemakers, Inc. | Multi-element acoustic recharging system |
| US8082041B1 (en) | 2007-06-15 | 2011-12-20 | Piezo Energy Technologies, LLC | Bio-implantable ultrasound energy capture and storage assembly including transmitter and receiver cooling |
| US20090018403A1 (en) | 2007-07-12 | 2009-01-15 | Sicel Technologies, Inc. | Trackable implantable sensor devices, systems, and related methods of operation |
| US20110288615A1 (en) | 2007-11-26 | 2011-11-24 | The Board Of Regents, The University Of Texas System | Implantable Therapeutic Systems Including Neurostimulation Circuits, Devices, Systems and Methods |
| WO2009075750A2 (en) | 2007-12-12 | 2009-06-18 | Cardiac Pacemakers, Inc. | System for delivering neurostimulation from pulmonary artery |
| US7953493B2 (en) | 2007-12-27 | 2011-05-31 | Ebr Systems, Inc. | Optimizing size of implantable medical devices by isolating the power source |
| US20090275997A1 (en) | 2008-05-01 | 2009-11-05 | Michael Allen Faltys | Vagus nerve stimulation electrodes and methods of use |
| US9364362B2 (en) | 2008-10-21 | 2016-06-14 | General Electric Company | Implantable device system |
| US8412338B2 (en) | 2008-11-18 | 2013-04-02 | Setpoint Medical Corporation | Devices and methods for optimizing electrode placement for anti-inflamatory stimulation |
| JP5581333B2 (ja) | 2008-12-18 | 2014-08-27 | サザン イノヴェーション インターナショナル プロプライアトリー リミテッド | 数学的変換を使用することによってパイルアップされたパルスを分離する方法および装置 |
| US9211410B2 (en) | 2009-05-01 | 2015-12-15 | Setpoint Medical Corporation | Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation |
| US8996116B2 (en) | 2009-10-30 | 2015-03-31 | Setpoint Medical Corporation | Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction |
| US20110054569A1 (en) | 2009-09-01 | 2011-03-03 | Zitnik Ralph J | Prescription pad for treatment of inflammatory disorders |
| US20120065458A1 (en) * | 2009-05-15 | 2012-03-15 | Koninklijke Philips Electronics N.V. | Implantable device with communication means |
| CN102573986B (zh) | 2009-06-09 | 2016-01-20 | 赛博恩特医疗器械公司 | 用于无导线刺激器的具有袋部的神经封套 |
| US20160331952A1 (en) | 2009-11-17 | 2016-11-17 | Michael A. Faltys | External programmer |
| US20150241447A1 (en) | 2009-11-17 | 2015-08-27 | Ralph J. ZITNIK | Vagus nerve stimulation screening test |
| WO2014169145A1 (en) | 2013-04-10 | 2014-10-16 | Setpoint Medical Corporation | Closed-loop vagus nerve stimulation |
| US9833621B2 (en) | 2011-09-23 | 2017-12-05 | Setpoint Medical Corporation | Modulation of sirtuins by vagus nerve stimulation |
| EP2515996B1 (en) | 2009-12-23 | 2019-09-18 | Setpoint Medical Corporation | Neural stimulation devices and systems for treatment of chronic inflammation |
| CA2797302C (en) | 2010-04-28 | 2019-01-15 | Ryerson University | System and methods for intraoperative guidance feedback |
| US9095284B2 (en) | 2010-10-28 | 2015-08-04 | Medtronic, Inc. | Distance measurement using implantable acoustic transducers |
| CA2831062A1 (en) | 2011-01-28 | 2012-08-02 | Stimwave Technologies Incorporated | Neural stimulator system |
| US9220897B2 (en) | 2011-04-04 | 2015-12-29 | Micron Devices Llc | Implantable lead |
| EP3586908B1 (en) | 2011-04-04 | 2024-11-13 | Curonix LLC | Implantable neural stimulator wireless lead |
| EP2704794A4 (en) * | 2011-05-06 | 2014-11-05 | Ndsu Res Foundation | SELF-ORGANIZING INTELLIGENT ELECTRODE STIMULATION DISPENSING SYSTEM |
| EP2707094B1 (en) | 2011-05-09 | 2016-02-03 | Setpoint Medical Corporation | Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation |
| WO2013003276A1 (en) | 2011-06-28 | 2013-01-03 | Pelican Imaging Corporation | Optical arrangements for use with an array camera |
| US9492678B2 (en) | 2011-07-14 | 2016-11-15 | Cyberonics, Inc. | Far field radiative powering of implantable medical therapy delivery devices |
| EP4356954B1 (en) | 2011-07-29 | 2024-12-11 | Curonix LLC | Remote control of power or polarity selection for a neural stimulator |
| EP3912675A1 (en) | 2011-08-12 | 2021-11-24 | Stimwave Technologies Incorporated | Microwave field stimulator |
| US8693633B2 (en) | 2011-09-08 | 2014-04-08 | Elwha Llc | Systems, devices, and methods including implants for managing cumulative x-ray radiation dosage |
| US8787526B2 (en) | 2011-09-08 | 2014-07-22 | Elwha Llc | Systems, devices, and methods including implants for managing cumulative X-ray radiation dosage including X-ray radiation direction determination devices |
| WO2013040549A1 (en) | 2011-09-15 | 2013-03-21 | Stimwave Technologies Incorporated | Relay module for implant |
| US9446255B2 (en) | 2011-11-13 | 2016-09-20 | Arizona Board of Regents on Behalf Arizona State University | Controlled stimulation delivery from neurostimulator |
| US20130178915A1 (en) | 2012-01-10 | 2013-07-11 | Piezo Energy Technologies, LLC | High power ultrasound wireless transcutaneous energy transfer (us-tet) source |
| WO2013134492A1 (en) | 2012-03-08 | 2013-09-12 | Medtronic Ardian Luxembourg Sarl | Neuromodulation and associated systems and methods for the treatment of sexual dysfunction |
| WO2013134479A1 (en) | 2012-03-08 | 2013-09-12 | Medtronic Ardian Luxembourg Sarl | Neuromodulation and associated systems and methods for the management of pain |
| BR112014028784B1 (pt) | 2012-05-21 | 2022-02-08 | Sensimed Sa | Sistema de monitoramento e/ou medição de pressão intraocular e dispositivo de medição de pressão intraocular |
| WO2013176744A1 (en) | 2012-05-22 | 2013-11-28 | Arizona Board Of Regents For And On Behalf Of Arizona State University | Apparatus, system, and method for neurostimulation by high frequency ultrasound |
| US10463858B2 (en) | 2012-07-17 | 2019-11-05 | Stimwave Technologies Incorporated | Devices and methods for treating craniofacial pain |
| US9717921B2 (en) | 2012-07-17 | 2017-08-01 | Micron Devices, LLC | Treating inflammation, chronic pain and other disorders with neuromodulation |
| WO2014153228A1 (en) | 2013-03-14 | 2014-09-25 | Perryman Laura Tyler | Miniature implantable device and methods |
| WO2014153218A1 (en) | 2013-03-14 | 2014-09-25 | Tyler Perryman Laura | Devices and methods for treating craniofacial pain |
| WO2014153219A1 (en) | 2013-03-14 | 2014-09-25 | Perryman Laura Tyler | Devices and methods for treating urological disorders |
| US10245436B2 (en) | 2012-07-17 | 2019-04-02 | Stimwave Technologies Incorporated | Miniature implantable device and methods |
| WO2014153223A1 (en) | 2013-03-14 | 2014-09-25 | Perryman Laura Tyler | Treating inflammation, chronic pain and other disorders with neuromodulation |
| US9623253B2 (en) | 2012-07-17 | 2017-04-18 | Micron Devices, LLC | Devices and methods for treating urological disorders |
| WO2014025894A1 (en) | 2012-08-07 | 2014-02-13 | The General Hospital Corporation | System and method for electrical impedance spectroscopy |
| HK1216305A1 (zh) | 2012-12-05 | 2016-11-04 | Curonix Llc | 用於将可植入装置连接至无线能量的装置和方法 |
| EP2953524B1 (en) * | 2013-02-06 | 2018-08-01 | Freenome Holdings Inc. | Systems and methods for early disease detection and real-time disease monitoring |
| CA2901310A1 (en) | 2013-02-22 | 2014-08-28 | Thync, Inc. | Methods and apparatuses for networking neuromodulation of a group of individuals |
| US8874233B2 (en) | 2013-03-05 | 2014-10-28 | The Charles Stark Draper Laboratory, Inc. | Distributed neuro-modulation system with auxiliary stimulation-recording control units |
| US9323397B2 (en) | 2013-03-11 | 2016-04-26 | The Regents Of The University Of California | In-air ultrasonic rangefinding and angle estimation |
| CA2902668A1 (en) * | 2013-03-15 | 2014-09-18 | Colibri Technologies Inc. | Active localization and visualization of minimally invasive devices using ultrasound |
| US10014570B2 (en) | 2013-05-13 | 2018-07-03 | The Board Of Trustees Of The Leland Stanford Junior University | Single transducer for data and power in wirelessly powered devices |
| WO2015019196A2 (en) * | 2013-08-09 | 2015-02-12 | Palti Yoram Prof | Passive data transmission |
| JP6050206B2 (ja) | 2013-09-17 | 2016-12-21 | 富士フイルム株式会社 | 放射線撮影システム及び通信環境制御装置 |
| US20170095198A1 (en) | 2014-03-17 | 2017-04-06 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods and Systems for Measuring Tissue Impedance and Monitoring PVD Treatment Using Neuro-Implants with Improved Ultrasound Powering |
| WO2015157347A1 (en) | 2014-04-07 | 2015-10-15 | Massachusetts Institute Of Technology | Intravascular device |
| JP2015211801A (ja) | 2014-05-07 | 2015-11-26 | セイコーエプソン株式会社 | 生体情報検出装置、生体情報提示システム及び電子機器 |
| US20170197082A1 (en) | 2014-07-09 | 2017-07-13 | Dexing Pang | Device, system and method for nerve stimulation |
| US11311725B2 (en) | 2014-10-24 | 2022-04-26 | Setpoint Medical Corporation | Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation |
| JP6043030B2 (ja) | 2014-12-17 | 2016-12-14 | オリンパス株式会社 | 管腔通過確認剤 |
| US10028659B2 (en) | 2015-03-26 | 2018-07-24 | Verily Life Sciences Llc | Aptamer-based sensors, implantable devices and detection system |
| BR112017022941A2 (pt) | 2015-04-24 | 2018-07-17 | Galvani Bioelectronics Limited | dispositivo de neuromodulação |
| US20170100604A1 (en) | 2015-05-15 | 2017-04-13 | Ohio State Innovation Foundation | Systems and methods of improving metabolic syndrome |
| US20170100589A1 (en) | 2015-05-15 | 2017-04-13 | Ohio State Innovation Foundation | Systems and methods of improving infections by neuromodulation of immune function |
| US20170100588A1 (en) | 2015-05-15 | 2017-04-13 | Ohio State Innovation Foundation | Systems and methods of improving cancer symptoms by neuromodulation of immune function |
| US20170100605A1 (en) | 2015-05-15 | 2017-04-13 | Ohio State Innovation Foundation | Systems and methods of improving an immune disorder |
| US20160331962A1 (en) | 2015-05-15 | 2016-11-17 | Ohio State Innovation Foundation | Methods for improving a patient's immune response |
| US10201706B2 (en) | 2015-05-15 | 2019-02-12 | Ohio State Innovation Foundation | Systems and methods of improving an inflammatory disorder |
| WO2017030900A1 (en) | 2015-08-14 | 2017-02-23 | The Regents Of The University Of California | Quantitative tool using impedance spectroscopy to monitor fracture healing |
| US10177606B2 (en) | 2015-10-21 | 2019-01-08 | The Board Of Trustees Of The Leland Stanford Junior University | Dynamic reconfiguration for maximizing the overall link efficiency of energy receivers in a reliable implantable system |
| WO2017149526A2 (en) | 2016-03-04 | 2017-09-08 | May Patents Ltd. | A method and apparatus for cooperative usage of multiple distance meters |
| EP4395124A3 (en) | 2016-03-21 | 2024-07-31 | Nalu Medical, Inc. | Devices and methods for positioning external devices in relation to implanted devices |
| EP3454737B1 (en) | 2016-03-31 | 2021-07-14 | Thomas Jefferson University | Tumor bed implant for multimodality treatment of at risk tissue surrounding a resection cavity |
| US9802055B2 (en) | 2016-04-04 | 2017-10-31 | Medtronic, Inc. | Ultrasound powered pulse delivery device |
| EP3468657B1 (en) | 2016-06-10 | 2022-05-11 | Purdue Research Foundation | System for wireless recording and stimulating of bioelectric events |
| US10232168B2 (en) * | 2016-06-27 | 2019-03-19 | Ecole Polytechnique Federale De Lausanne (Epfl) | System for active skull replacement for brain interface and method of using the same |
| CA3029899A1 (en) * | 2016-07-07 | 2018-01-11 | The Regents Of The University Of California | Implants using ultrasonic backscatter for detecting electrophysiological signals |
| WO2018026816A1 (en) | 2016-08-01 | 2018-02-08 | Immunolight, Llc | Phosphor-containing drug activator activatable by a monte carlo derived x-ray exposure, system containing the activator, and methods for use |
| US20200046992A1 (en) | 2016-10-31 | 2020-02-13 | The Feinstein Institute For Medical Research | Techniques for neuromodulation using electromagnetic energy |
| EP3538209A1 (en) | 2016-11-08 | 2019-09-18 | Galvani Bioelectronics Limited | Treatment of inflammatory disorders |
| EP3538210A2 (en) | 2016-11-14 | 2019-09-18 | Galvani Bioelectronics Limited | Modular neuromodulation systems, methods of manufacture, and methods of treating rheumatoid arthritis |
| US10940329B2 (en) | 2016-11-22 | 2021-03-09 | Immunolight, Llc | Phosphor-containing drug activator activatable by a Monte Carlo derived x-ray exposure, system containing the activator, and methods for use |
| WO2018118861A1 (en) | 2016-12-19 | 2018-06-28 | Ohio State Innovation Foundation | Systems and methods of improving cancer symptoms by neuromodulation of immune function |
| WO2018118860A1 (en) | 2016-12-19 | 2018-06-28 | Ohio State Innovation Foundation | Systems and methods of improving an inflammatory disorder |
| WO2018118857A1 (en) | 2016-12-19 | 2018-06-28 | Ohio State Innovation Foundation | Systems and methods of improving an immune disorder |
| EP3658958A4 (en) | 2017-07-26 | 2021-04-14 | RefleXion Medical, Inc. | GRAPHIC REPRESENTATION OF RADIOTHERAPY |
| CA3097139A1 (en) | 2018-04-19 | 2019-10-24 | Jose M. Carmena | Implants using ultrasonic communication for modulating splenic nerve activity |
| CN112272575B (zh) | 2018-04-19 | 2024-05-17 | 艾奧塔生物科技公司 | 使用用于神经感测和刺激的超声通信的植入物 |
| US11857316B2 (en) | 2018-05-07 | 2024-01-02 | Hi Llc | Non-invasive optical detection system and method |
| PL3843830T3 (pl) | 2018-08-29 | 2024-08-12 | Iota Biosciences, Inc. | Wszczepialne urządzenie do neuromodulacji w zamkniętej pętli |
| WO2020117967A1 (en) | 2018-12-06 | 2020-06-11 | Iota Biosciences, Inc. | Device networks for modulating neural activity |
| JP7520847B2 (ja) | 2019-01-04 | 2024-07-23 | イオタ バイオサイエンシズ, インコーポレイテッド | 超音波を使用して電力を供給するインプランタブルデバイスの電力制御 |
| PT3906091T (pt) | 2019-01-04 | 2024-08-13 | Iota Biosciences Inc | Protocolo baseado em ultrassom para operação de um dispositivo implantável |
| US20200410189A1 (en) | 2019-06-27 | 2020-12-31 | Qualcomm Incorporated | Biometric fingerprint photoacoustic tomographic imaging |
| US20230095948A1 (en) | 2020-02-19 | 2023-03-30 | The Regents Of The University Of California | A deep tissue ultrasonic implantable luminescence oxygen sensor |
| WO2021168163A1 (en) | 2020-02-19 | 2021-08-26 | Chan Zuckerberg Biohub, Inc. | Anchor loss in millimeter-scale ultrasonic wireless implantable devices |
| US11963683B2 (en) * | 2020-10-02 | 2024-04-23 | Cilag Gmbh International | Method for operating tiered operation modes in a surgical system |
-
2017
- 2017-07-07 CA CA3029899A patent/CA3029899A1/en active Pending
- 2017-07-07 US US16/313,860 patent/US11607128B2/en active Active
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140336474A1 (en) * | 2013-05-13 | 2014-11-13 | The Board Of Trustees Of The Leland Stanford Junior University | Hybrid communication system for implantable devices and ultra-low power sensors |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP4258998A4 (en) * | 2020-12-08 | 2025-01-01 | Geegah LLC | IMAGING AND DETECTION OF A THIN FILM WITH HIGH FREQUENCY ULTRASONIC TRANSDUCERS |
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| CN116541896A (zh) * | 2023-07-06 | 2023-08-04 | 北京领创医谷科技发展有限责任公司 | 一种植入设备识别电路、植入设备及读取设备 |
| CN116541896B (zh) * | 2023-07-06 | 2023-09-12 | 北京领创医谷科技发展有限责任公司 | 一种植入设备识别电路、植入设备及读取设备 |
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