CN109464644A - Radix Angelicae Sinensis motherwort massage oil, preparation method and its application - Google Patents

Radix Angelicae Sinensis motherwort massage oil, preparation method and its application Download PDF

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Publication number
CN109464644A
CN109464644A CN201811645014.3A CN201811645014A CN109464644A CN 109464644 A CN109464644 A CN 109464644A CN 201811645014 A CN201811645014 A CN 201811645014A CN 109464644 A CN109464644 A CN 109464644A
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extract
motherwort
radix angelicae
angelicae sinensis
oil
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李淳廉
王孝慈
简光廷
张晓林
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Shenzhen Chun Rui Trade Co Ltd
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Shenzhen Chun Rui Trade Co Ltd
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Abstract

The embodiment of the invention discloses a kind of Radix Angelicae Sinensis motherwort massage oil, preparation method and its applications.Wherein, the Radix Angelicae Sinensis motherwort massage oil includes following ingredient: substrate oil, Radix Angelicae Sinensis, the fruit of glossy privet, Vitex negundo var cannabifolia, Rhizoma Chuanxiong, motherwort, cortex cinnamomi, ginger, Clary Sage, wormwood, Zhu jasmine and nutmeg.The Radix Angelicae Sinensis motherwort massage oil plays the drug effect of plurality of Chinese compatibility generation in the form of massaging essential oil, premenstrual syndrome (PMS) can effectively be alleviated, especially menstrual period fore udder goes up painful and the problem of oedema, dysmenorrhea can also be improved, irregular menstruation and Menopause obstacle, the common gynaecological problem such as climacteric osteoporosis, has a good application prospect.

Description

Radix Angelicae Sinensis motherwort massage oil, preparation method and its application
Technical field
The present invention relates to health product technology field more particularly to a kind of Radix Angelicae Sinensis motherwort massage oil, preparation method and its Using.
Background technique
The modes such as boiling repeatedly are generallyd use when traditional Chinese materia medica preparation, the water soluble compound in a variety of drugs is enabled to pass through After the processing such as high temperature, be dissolved in the water or solvent that other are different in so that Chinese materia medica preparation can pass through oral side Formula enters human body, be absorbed by the body and reach health or health care and other effects.
But existing Chinese medicine material much all contains the harmful toxicants such as plasticiser, heavy metal, pesticide residue, no It is preferably taken and absorbs by human body.Moreover, the solvent introduced in the manufacturing process of some Chinese medicines may also pollute, the medicine of Chinese medicine Reason characteristic may be difficult to be embodied as, and quality control is not easy up to standard.
In addition, existing western medicine is fairly simple for the therapeutic modality of many gynecological diseases directly, therapeutic effect is not It is good, especially some chronic illnesss.Therefore, there is an urgent need to provide a kind of to alleviate the new of gynecological disease and pain for treating Chinese medicine composition.
Summary of the invention
In view of the above technical problems, the embodiment of the invention provides a kind of Radix Angelicae Sinensis motherwort massage oil, preparation method and It is applied, and is not easy to embody to solve the pharmacological action of present traditional Chinese medicine preparation, chronic gynecological disease problem difficult to treat.
The first aspect of the embodiment of the present invention provides a kind of Radix Angelicae Sinensis motherwort massage oil.Wherein, the Radix Angelicae Sinensis motherwort is pressed The oil that rubs includes following ingredient: substrate oil, Radix Angelicae Sinensis, the fruit of glossy privet, Vitex negundo var cannabifolia, Rhizoma Chuanxiong, motherwort, cortex cinnamomi, ginger, Clary Sage, wormwood, Zhu jasmine and nutmeg.
Optionally, the substrate oil is mixed to form by Sweet Almond Oil and SIMMONDSIA CHINENSIS SEED OIL with 3 to 2 ratio.
Optionally, the Radix Angelicae Sinensis motherwort massage oil is by Chinese angelica root extract, fruit of glossy privet extract, Vitex negundo var cannabifolia extract, Rhizoma Chuanxiong Extract, motherwort extract, cinnamon extract, ginger extract, Clary Sage extract, wormwood extract, Zhu jasmine Hua Cui Object and nutmeg extract is taken to mix acquisition with the substrate oil by preset adding proportion.
Optionally, the Chinese angelica root extract, fruit of glossy privet extract, Vitex negundo var cannabifolia extract, Rhizoma Chuanxiong extract, motherwort extraction Object, cinnamon extract, ginger extract, Clary Sage extract, wormwood extract, Zhu jasmine extracts and nutmeg extraction The adding proportion of object is 1:1:1:1:1:2:2:4:1:2:2.
Optionally, by weight, in every 100g substrate oil, it is added with following ingredient:
The second aspect of the embodiment of the present invention additionally provides the preparation method of Radix Angelicae Sinensis motherwort massage oil as described above.Its In, the preparation method includes:
Weigh Radix Angelicae Sinensis, the fruit of glossy privet, Vitex negundo var cannabifolia, Rhizoma Chuanxiong, motherwort, cortex cinnamomi, ginger, Clary Sage, wormwood, Zhu jasmine and meat Cardamom raw material;
By ultrahigh speed vacuum hydro-extraction method, the Radix Angelicae Sinensis is extracted, the fruit of glossy privet, Vitex negundo var cannabifolia, Rhizoma Chuanxiong, motherwort, cortex cinnamomi is ginger, fast Active drug ingredient in happy Salvia japonica, wormwood, Zhu jasmine and nutmeg raw material, obtains corresponding Chinese angelica root extract, glossy privet Sub- extract, Vitex negundo var cannabifolia extract, Rhizoma Chuanxiong extract, motherwort extract, cinnamon extract, ginger extract, Clary Sage extraction Take object, wormwood extract, Zhu jasmine extracts and nutmeg extract;
By the Chinese angelica root extract, fruit of glossy privet extract, Vitex negundo var cannabifolia extract, Rhizoma Chuanxiong extract, motherwort extract, cortex cinnamomi Extract, ginger extract, Clary Sage extract, wormwood extract, Zhu jasmine extracts and nutmeg extract are by pre- If ratio is added in substrate oil, the Radix Angelicae Sinensis motherwort massage oil is obtained.
Optionally, the ultrahigh speed vacuum hydro-extraction method includes:
In the case where being higher than critical-temperature and pressure, compression fluid is to form supercritical fluid;
Use the active drug ingredient of the supercritical fluid extraction raw material;
Pressure and temperature is all restored to normal temperature and pressure, so that active drug ingredient is separated with gaseous fluid.
Optionally, the substrate oil is the high volatile oily liquids that Sweet Almond Oil and SIMMONDSIA CHINENSIS SEED OIL form.
Optionally, the method also includes: pass through high performance liquid chromatography chromatography and detect the Radix Angelicae Sinensis motherwort massage oil Whether preset quality standard is met.
The third aspect of the embodiment of the present invention additionally provides application of the Radix Angelicae Sinensis motherwort massage oil in point massage.
In technical solution provided in an embodiment of the present invention, the Radix Angelicae Sinensis motherwort massage oil by by Chinese materia medica preparation be made as by It rubs the form of essential oil, can enable its effective ingredient that can be absorbed by the human body via skin and smell, reach good guarantor Strong and medical effect is conducive to control product quality and avoids the intake of harmful toxic matter.
Moreover, Radix Angelicae Sinensis motherwort massage oil can effectively alleviate premenstrual syndrome (PMS) by a variety of compatibility of drugs, Especially menstrual period fore udder goes up painful and the problem of oedema, can also improve dysmenorrhea, irregular menstruation and Menopause obstacle, climacteric It the problems such as phase osteoporosis, has a good application prospect.
Detailed description of the invention
Fig. 1 is one embodiment schematic diagram of the preparation method of Radix Angelicae Sinensis motherwort massage oil provided in an embodiment of the present invention;
Fig. 2 is one embodiment schematic diagram of ultrahigh speed vacuum hydro-extraction equipment provided in an embodiment of the present invention;
Fig. 3 is one embodiment schematic diagram of human acupoint provided in an embodiment of the present invention distribution.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, those skilled in the art's every other implementation obtained without creative efforts Example, shall fall within the protection scope of the present invention.
It should be noted that be expressed " being fixed on " another element when element, it can directly on the other element, Or there may be one or more elements placed in the middle therebetween.When an element is expressed " connection " another element, it can be with It is directly to another element or there may be one or more elements placed in the middle therebetween.Used in this specification The orientation or position of the instructions such as term "vertical", "horizontal", "left" and "right", "upper", "lower", "inner", "outside", " bottom " Relationship is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of description of the present invention and simplification of the description, without referring to Show or imply that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore cannot manage Solution is limitation of the present invention.In addition, term " first ", " second " etc. are used for description purposes only, and should not be understood as instruction or Imply relative importance.
Unless otherwise defined, technical and scientific term all used in this specification is led with technology of the invention is belonged to The normally understood meaning of the technical staff in domain is identical.Used term is only in the description of the invention in this specification The purpose of description specific embodiment is not intended to limitation the utility model.Term "and/or" used in this specification Including any and all combinations of one or more related listed items.In addition, invention described below is different Technical characteristic involved in embodiment can be combined with each other as long as they do not conflict with each other.
The embodiment of the invention provides a kind of Radix Angelicae Sinensis motherwort massage oils.Wherein, the Radix Angelicae Sinensis motherwort massage oil includes Following ingredient: substrate oil, substrate oil, Radix Angelicae Sinensis, the fruit of glossy privet, Vitex negundo var cannabifolia, Rhizoma Chuanxiong, motherwort, cortex cinnamomi, ginger, Clary Sage, wormwood, Zhu jasmine and nutmeg.
The substrate oil is the oily liquids with high volatile.Specifically, it can be pressed by Sweet Almond Oil and SIMMONDSIA CHINENSIS SEED OIL It is mixed according to 3 to 2 ratio.SIMMONDSIA CHINENSIS SEED OIL is from Jojoba (Jojoba also known as Jojoba, a kind of plant that Mexico is primary Object) in extraction obtain oil.
Wherein, the chemical molecular arrangement of Jojoba Oil is very similar with the sebum of the mankind, belongs to wax quality and on-liquid Quality is easy to rapidly enter human body in effective ingredient wherein in can help to add by skin and absorption, send out Wave effectiveness.
Based on the substrate oil, Radix Angelicae Sinensis, the fruit of glossy privet, Vitex negundo var cannabifolia, Rhizoma Chuanxiong, motherwort, cortex cinnamomi, ginger, happy rat-tail are added Grass, wormwood, the Radix Angelicae Sinensis motherwort massage oil that the active drugs ingredient such as Zhu jasmine and nutmeg is formed have warming kidney and enhancing yang, promoting the circulation of qi The effect of promoting blood circulation.
It can apply the efficacy of a drug by modes such as massages, have some setbacks suitable for menstrual period, dysmenorrhea, clot, menostaxis, blood volume Few, Climacteric, trick is ice-cold, the crowds such as leukorrhea and the cold of insufficiency type.
In some embodiments, which can be by Chinese angelica root extract, fruit of glossy privet extract, Vitex negundo var cannabifolia extraction Take object, Rhizoma Chuanxiong extract, motherwort extract, cinnamon extract, ginger extract, Clary Sage extract, wormwood extract, Zhu jasmine extracts and nutmeg extract press preset adding proportion and mix acquisition with the substrate oil.
Radix Angelicae Sinensis motherwort massage oil obtained, which can be closed, to be kept in dark place in the containers such as vial, and taking out in massage makes With.
In the Radix Angelicae Sinensis motherwort massage essential oil of the present embodiment, the Vitex negundo var cannabifolia containing referred to as chaste and undefiled tree has outstanding enrich blood The Radix Angelicae Sinensis and the fruit of glossy privet of effect, the motherwort of qi-blood tonifying Rhizoma Chuanxiong and most blood circulation.
By the mutual compatibility of these traditional Chinese medicinal components, the effect of warming kidney and enhancing yang and the promoting flow of qi and blood circulation can have, be suitable for alleviating Premenstrual syndrome (PMS) is especially menstrual period fore udder and goes up painful and the problem of oedema, and improves dysmenorrhea, irregular menstruation and women climacteric The problems such as phase obstacle, climacteric osteoporosis.
Certainly, it should be noted that the Radix Angelicae Sinensis motherwort massage oil should not make because of its pharmacological property, child and Pregnant women With.
Specifically, massage oil is by weight, described work as can be made added with following ingredient in every 100g substrate oil Return motherwort massage oil:
Also that is, the Chinese angelica root extract, fruit of glossy privet extract, Vitex negundo var cannabifolia extract, Rhizoma Chuanxiong extract, motherwort extract, Cinnamon extract, ginger extract, Clary Sage extract, wormwood extract, Zhu jasmine extracts and nutmeg extract Adding proportion can control in 1:1:1:1:1:2:2:4:1:2:2.
It is preferred that the Radix Angelicae Sinensis motherwort massage oil is in factory before use, can be by gas-chromatography and mass spectral analysis etc. Method is detected, and determines whether objectionable impurities content is detected or whether can meet preset safety standard, to have The quality for having ensured Radix Angelicae Sinensis motherwort massage oil of effect.
In the actual use process of Radix Angelicae Sinensis motherwort massage oil, as shown in figure 3, both can be in lower abdomen conception vessel and punching Arteries and veins, dai channel massage when use, can be used for menstrual period and the underbelly massage of non-menstrual period.The position specifically massaged with navel with Down toward pelvic on both sides and side waist, leg is then based on the massage of thigh and medial leg.
Clinical real example:
Based on above massaging way, using Radix Angelicae Sinensis motherwort massage oil provided in an embodiment of the present invention to 100 trouble After person carries out health care massage treatment 1 month, the feedback information discovery of user is counted:
Many ill symptoms have all obtained different degrees of improvement, wherein the user's quantity to make moderate progress according to symptom The percentage for accounting for total number of persons calculates, and dysmenorrhoea 90% had a headache 85% before menstrual period, blood volume few 80%, Climacteric 80%, warp Phase has some setbacks 70%, leukorrhea 60%.
Usually there is water boiling method for the extracting method of the effective component in Traditional Chinese medicine raw material, infusion process, percolation, change Good gelatin method, circumfluence method and solvent extraction method etc. are several.
For example, solvent extraction method is most widely used method.Its principle is molten according to effective components various in Chinese herbal medicine The property of Xie Du, is selected to needing ingredient solubility big and the solvent small to other compositions solubility, by required activity at Divide and is extracted out of medicinal material tissue.
Steam distillation rule is can be with steam distillation, without the one kind being destroyed using the effective component in Chinese medicine Extracting method.Its extraction for being mainly used for aqua aromatica and volatile oil.The principle of this method is dalton principle --- it is mutually insoluble Also the steam stagnation pressure of chemically inert liquid mixture, equal to the sum of the saturation pressure of each component at this temperature.It is such, to the greatest extent The boiling point of pipe each component itself is higher than the boiling point of mixed liquor, but when dividing summation equal to atmospheric pressure, liquid mixture starts It boils and is distilled off.
Based on one or more kinds of defects or deficiency present in these traditional extracting methods, the embodiment of the present invention Second aspect additionally provides the preparation method of Radix Angelicae Sinensis motherwort massage oil as described above.Fig. 1 is provided in an embodiment of the present invention The method schematic diagram of preparation method.Fig. 2 is the structural schematic diagram of Preparation equipment provided in an embodiment of the present invention.Based on Fig. 1 and Fig. 2 Shown in preparation method better raw material abstraction efficiency can be provided.It as depicted in figs. 1 and 2, may include following specific step It is rapid:
100, weigh Radix Angelicae Sinensis, the fruit of glossy privet, Vitex negundo var cannabifolia, Rhizoma Chuanxiong, motherwort, cortex cinnamomi, ginger, Clary Sage, wormwood, Zhu jasmine with And nutmeg raw material.
In some embodiments, it is (such as clear that the one or more kinds of pre-treatment steps of raw material progress can also be obtained to acquisition Wash, be cut to fragment etc.), in order to subsequent extraction work and guarantee product quality.
200, by ultrahigh speed vacuum hydro-extraction method, the Radix Angelicae Sinensis is extracted, the fruit of glossy privet, Vitex negundo var cannabifolia, Rhizoma Chuanxiong, motherwort, cortex cinnamomi, Active drug ingredient in ginger, Clary Sage, wormwood, Zhu jasmine and nutmeg raw material, obtains corresponding Chinese angelica root extract, Fruit of glossy privet extract, Vitex negundo var cannabifolia extract, Rhizoma Chuanxiong extract, motherwort extract, cinnamon extract, ginger extract, happy rat-tail Careless extract, wormwood extract, Zhu jasmine extracts and nutmeg extract.
As shown in Fig. 2, the extraction equipment include: oil pressure cylinder 11, vacuum shell 12, glass visit window 13, cooling device 14, Distilled water storage barrel 15, cooling water radiator 16, revolution pumping 17 and vacuum pump 18.
The extraction process of its ultrahigh speed vacuum hydro-extraction method approximately as: firstly, inside vacuum shell 12 carry out low temperature thickening With the process of low temperature distillation (glass visits window can be to observe the treatment process of raw material) so that effective medicine of traditional Chinese medicinal material raw materials Object ingredient is substantially dissolved in shooting flow body.Then, pressure and temperature is all restored to normal temperature and pressure, enables supercritical fluid extensive It is again gaseous fluid, so that being dissolved in active drug ingredient therein and gaseous fluid quick separating, realizes finally for effective The extraction operation of ingredient.
300, by the Chinese angelica root extract, fruit of glossy privet extract, Vitex negundo var cannabifolia extract, Rhizoma Chuanxiong extract, motherwort extract, Cinnamon extract, ginger extract, Clary Sage extract, wormwood extract, Zhu jasmine extracts and nutmeg extract It is added in substrate oil by preset ratio, obtains the Radix Angelicae Sinensis motherwort massage oil.
Specifically, the substrate oil is the high volatile oily liquids that Sweet Almond Oil and SIMMONDSIA CHINENSIS SEED OIL form.It can be adopted It is mixed and is formed with suitable ratio, such as every 100g substrate oil is mixed with 60g Sweet Almond Oil and 40g SIMMONDSIA CHINENSIS SEED OIL.
Preferably, it is also necessary to which detecting the Radix Angelicae Sinensis motherwort massage oil using high performance liquid chromatography chromatography (HPLC) is It is no that there are excessive harmful substances.If then abandoning and remaking, to ensure that the Radix Angelicae Sinensis motherwort massage oil can be by safety Use.
Specifically, needing detected harmful substance includes following some projects: organic phosphorus and Carbamates agriculture Medicine residual, borax, formaldehyde, sulfur dioxide, hydrogen peroxide, nitrite, nitrate, sodium formaldehyde sulfoxylate, protein and heavy metal lead.
Certainly, which can also further roll over coloration, rotation brightness, specific gravity, oily oxygen after testing The detections such as agent test are to ensure the quality of essential oil and meet the standard detection project of inlet and outlet COA.
In conclusion the Radix Angelicae Sinensis motherwort massage oil provided through the embodiment of the present invention passes through modern extracting process, will in The form of massage essential oil, the side that the effective ingredient of Chinese medicine material can be made to be absorbed by stomach is made in medicine active drug ingredient Formula becomes completing by skin and smell, has very good health-care effect, it is not easy to the harmful substances such as heavy metal occur Deng excessive intake and it is advantageously ensured that good quality.
Moreover, can effectively alleviate premenstrual syndrome (PMS), especially menstrual period fore udder by a variety of compatibility of drugs It goes up painful and the problem of oedema, dysmenorrhea, irregular menstruation and Menopause obstacle can also be improved, climacteric osteoporosis etc. is asked Topic.
It, can according to the technique and scheme of the present invention and this hair it is understood that for those of ordinary skills Bright design is subject to equivalent substitution or change, and all these changes or replacement all should belong to the guarantor of appended claims of the invention Protect range.

Claims (10)

1. a kind of Radix Angelicae Sinensis motherwort massage oil, which is characterized in that the Radix Angelicae Sinensis motherwort massage oil includes following ingredient: substrate Oil, Radix Angelicae Sinensis, the fruit of glossy privet, Vitex negundo var cannabifolia, Rhizoma Chuanxiong, motherwort, cortex cinnamomi, ginger, Clary Sage, wormwood, Zhu jasmine and nutmeg.
2. Radix Angelicae Sinensis motherwort massage oil according to claim 1, which is characterized in that the substrate oil is by Sweet Almond Oil and lotus Lotus bar oil is mixed to form with 3 to 2 ratio.
3. Radix Angelicae Sinensis motherwort massage oil according to claim 1, which is characterized in that the Radix Angelicae Sinensis motherwort massage oil is by working as Return extract, fruit of glossy privet extract, Vitex negundo var cannabifolia extract, Rhizoma Chuanxiong extract, motherwort extract, cinnamon extract, ginger extract, Clary Sage extract, wormwood extract, Zhu jasmine extracts and nutmeg extract press preset adding proportion and institute The mixing of substrate oil is stated to obtain.
4. Radix Angelicae Sinensis motherwort massage oil according to claim 3, which is characterized in that the Chinese angelica root extract, fruit of glossy privet extraction Take object, Vitex negundo var cannabifolia extract, Rhizoma Chuanxiong extract, motherwort extract, cinnamon extract, ginger extract, Clary Sage extract, The adding proportion of wormwood extract, Zhu jasmine extracts and nutmeg extract is 1:1:1:1:1:2:2:4:1:2:2.
5. Radix Angelicae Sinensis motherwort massage oil according to claim 4, which is characterized in that by weight, in every 100g substrate oil In, it is added with following ingredient:
6. a kind of preparation method of Radix Angelicae Sinensis motherwort massage oil, which is characterized in that the preparation method includes:
Weigh Radix Angelicae Sinensis, the fruit of glossy privet, Vitex negundo var cannabifolia, Rhizoma Chuanxiong, motherwort, cortex cinnamomi, ginger, Clary Sage, wormwood, Zhu jasmine and nutmeg Raw material;
By ultrahigh speed vacuum hydro-extraction method, the Radix Angelicae Sinensis, the fruit of glossy privet, Vitex negundo var cannabifolia, Rhizoma Chuanxiong, motherwort, cortex cinnamomi, ginger, happy mouse are extracted Tail is careless, wormwood, the active drug ingredient in Zhu jasmine and nutmeg raw material, obtains corresponding Chinese angelica root extract, fruit of glossy privet extraction Take object, Vitex negundo var cannabifolia extract, Rhizoma Chuanxiong extract, motherwort extract, cinnamon extract, ginger extract, Clary Sage extract, Wormwood extract, Zhu jasmine extracts and nutmeg extract;
By the Chinese angelica root extract, fruit of glossy privet extract, Vitex negundo var cannabifolia extract, Rhizoma Chuanxiong extract, motherwort extract, cortex cinnamomi extraction Object, ginger extract, Clary Sage extract, wormwood extract, Zhu jasmine extracts and nutmeg extract are by default ratio Example is added in substrate oil, obtains the Radix Angelicae Sinensis motherwort massage oil.
7. preparation method according to claim 6, which is characterized in that the ultrahigh speed vacuum hydro-extraction method includes:
In the case where being higher than critical-temperature and pressure, compression fluid is to form supercritical fluid;
Use the active drug ingredient of the supercritical fluid extraction raw material;
Pressure and temperature is all restored to normal temperature and pressure, so that the active drug ingredient is separated with gaseous fluid.
8. preparation method according to claim 6, which is characterized in that the substrate oil is Sweet Almond Oil and SIMMONDSIA CHINENSIS SEED OIL group At high volatile oily liquids.
9. preparation method according to claim 6, which is characterized in that the method also includes: pass through high performance liquid chromatography Chromatography detects whether the Radix Angelicae Sinensis motherwort massage oil meets preset quality standard.
10. application of the Radix Angelicae Sinensis motherwort massage oil a method as claimed in any one of claims 1 to 5 in point massage.
CN201811645014.3A 2018-12-29 2018-12-29 Radix Angelicae Sinensis motherwort massage oil, preparation method and its application Pending CN109464644A (en)

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