CN109568425A - Flower bud of lily magnolia massage oil, preparation method and its application - Google Patents

Flower bud of lily magnolia massage oil, preparation method and its application Download PDF

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Publication number
CN109568425A
CN109568425A CN201910002708.3A CN201910002708A CN109568425A CN 109568425 A CN109568425 A CN 109568425A CN 201910002708 A CN201910002708 A CN 201910002708A CN 109568425 A CN109568425 A CN 109568425A
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China
Prior art keywords
flower bud
lily magnolia
oil
extract
massage
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CN201910002708.3A
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Inventor
李淳廉
王孝慈
简光廷
张晓林
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Shenzhen Chun Rui Trade Co Ltd
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Shenzhen Chun Rui Trade Co Ltd
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Priority to CN201910002708.3A priority Critical patent/CN109568425A/en
Publication of CN109568425A publication Critical patent/CN109568425A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The embodiment of the invention discloses a kind of flower bud of lily magnolia massage oil, preparation method and its applications.Wherein, the flower bud of lily magnolia massage oil includes following ingredient: substrate oil, ginkgo, the flower bud of lily magnolia, peppermint, rosemary and lemon.The advantages of flower bud of lily magnolia massage oil combines west essential oil, enables Chinese medicine effective component that can be absorbed by the human body via skin and smell, avoids the intake of noxious material, reaches good health care and medical effect.Refresh the mind sensible moreover, the flower bud of lily magnolia massage oil has, the effect of unimpeded respiratory tract, for having a stuffy nose, feeling dizzy, pressure is big, and the drowsiness and spiritual illnesss such as not good have good improvement result.

Description

Flower bud of lily magnolia massage oil, preparation method and its application
Technical field
The present invention relates to health product technology field more particularly to a kind of flower bud of lily magnolia massage oils, preparation method and its application.
Background technique
The modes such as boiling repeatedly are generallyd use when traditional Chinese materia medica preparation, the water soluble compound in a variety of drugs is enabled to pass through After the processing such as high temperature, be dissolved in the water or solvent that other are different in so that preparation can by way of oral into Enter human body, be absorbed by the body and reach health or health care and other effects.
But existing Chinese medicine material much all contains the harmful toxicants such as plasticiser, heavy metal, pesticide residue, no It is preferably taken and absorbs by human body.The solvent introduced in some manufacturing process may also pollute, so that the pharmacological property of Chinese medicine It may be difficult to be embodied as.
Now there is an urgent need to provide a kind of new Chinese materia medica preparation form, preferably to play the health-care effect of Chinese medicine.
Summary of the invention
In view of the above technical problems, the embodiment of the invention provides a kind of flower bud of lily magnolia massage oil, preparation method and its application, To solve the problem of that the pharmacological action of present traditional Chinese medicine preparation is not easy to embody that oral there are harmful substances to take in risk.
The first aspect of the embodiment of the present invention provides a kind of flower bud of lily magnolia massage oil.Wherein, the flower bud of lily magnolia massage oil includes as follows Ingredient: substrate oil, ginkgo, the flower bud of lily magnolia, peppermint, rosemary and lemon.
Optionally, the substrate oil is mixed to form by Sweet Almond Oil and SIMMONDSIA CHINENSIS SEED OIL with 3 to 2 weight ratio.
Optionally, the flower bud of lily magnolia massage oil is by biloba extract object, flower bud of lily magnolia extract, peppermint extract, rosemary extract And lemon extract mixes acquisition with the substrate oil by preset adding proportion.
Optionally, the biloba extract object, flower bud of lily magnolia extract, peppermint extract, rosemary extract and lemon extraction The adding proportion of object is 2:1:4:4:4.
Optionally, by weight, in every 100g substrate oil, it is added with following ingredient:
The second aspect of the embodiment of the present invention additionally provides the preparation method of flower bud of lily magnolia massage oil as described above.Wherein, institute Stating preparation method includes:
Pre-process ginkgo, the flower bud of lily magnolia, peppermint, rosemary and lemon raw material;
By ultrahigh speed vacuum hydro-extraction method, the ginkgo is extracted, the flower bud of lily magnolia, peppermint, having in rosemary and lemon raw material Drug ingedient is imitated, corresponding biloba extract object, flower bud of lily magnolia extract, peppermint extract, rosemary extract and lemon extraction are obtained Take object;
By the biloba extract object, flower bud of lily magnolia extract, peppermint extract, rosemary extract and lemon extract by pre- If ratio is added in substrate oil, the flower bud of lily magnolia massage oil is obtained.
Optionally, the ultrahigh speed vacuum hydro-extraction method includes:
In the case where being higher than critical-temperature and pressure, compression fluid is to form supercritical fluid;
Use the active drug ingredient of the supercritical fluid extraction raw material;
Pressure and temperature is all restored to normal temperature and pressure, so that active drug ingredient is separated with gaseous fluid.
Optionally, the substrate oil is the high volatile oily liquids that Sweet Almond Oil and SIMMONDSIA CHINENSIS SEED OIL form.
Optionally, the method also includes: detect whether the flower bud of lily magnolia massage oil accords with by high performance liquid chromatography chromatography Close preset quality standard.
The third aspect of the embodiment of the present invention additionally provides application of the flower bud of lily magnolia massage oil in point massage.
In technical solution provided in an embodiment of the present invention, which enables addition in the form of essential oil is massaged in west Chinese medicine effective component in substrate oil can be directly absorbed by the human body via skin and smell, reach good health care And medical effect.
Such mode does not need the absorption by gastrointestinal tract, and can effectively avoid can also while taking in harmful substance To control the quality of essential oil product well, meet various quality standards based on modern detection technique.
Moreover, the flower bud of lily magnolia massage oil is sensible with refreshing the mind, the effect of unimpeded respiratory tract, massaging way is simple, for It has a stuffy nose, feel dizzy, pressure is big, and the drowsiness and spiritual illnesss such as not good have good improvement result, has good application Prospect.
Detailed description of the invention
Fig. 1 is one embodiment schematic diagram of the preparation method of flower bud of lily magnolia massage oil provided in an embodiment of the present invention;
Fig. 2 is one embodiment schematic diagram of ultrahigh speed vacuum hydro-extraction equipment provided in an embodiment of the present invention;
Fig. 3 is one embodiment schematic diagram of human acupoint provided in an embodiment of the present invention distribution.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, those skilled in the art's every other implementation obtained without creative efforts Example, shall fall within the protection scope of the present invention.
It should be noted that be expressed " being fixed on " another element when element, it can directly on the other element, Or there may be one or more elements placed in the middle therebetween.When an element is expressed " connection " another element, it can be with It is directly to another element or there may be one or more elements placed in the middle therebetween.Used in this specification The orientation or position of the instructions such as term "vertical", "horizontal", "left" and "right", "upper", "lower", "inner", "outside", " bottom " Relationship is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of description of the present invention and simplification of the description, without referring to Show or imply that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore cannot manage Solution is limitation of the present invention.In addition, term " first ", " second " etc. are used for description purposes only, and should not be understood as instruction or Imply relative importance.
Unless otherwise defined, technical and scientific term all used in this specification is led with technology of the invention is belonged to The normally understood meaning of the technical staff in domain is identical.Used term is only in the description of the invention in this specification The purpose of description specific embodiment is not intended to the limitation present invention.Term "and/or" used in this specification includes Any and all combinations of one or more related listed items.In addition, invention described below difference is implemented Technical characteristic involved in mode can be combined with each other as long as they do not conflict with each other.
The embodiment of the invention provides a kind of flower bud of lily magnolia massage oils.Wherein, the flower bud of lily magnolia massage oil is by as follows at being grouped as: base Base oil, ginkgo, the flower bud of lily magnolia, peppermint, rosemary and lemon.
The substrate oil exists in the form of the oily liquids of high volatile.Its basic ingredient as massage oil, assists to add Drug ingedient therein is added in be absorbed by the body as far as possible.Specifically, substrate oil can be pressed by Sweet Almond Oil and SIMMONDSIA CHINENSIS SEED OIL It is mixed according to 3 to 2 ratio.SIMMONDSIA CHINENSIS SEED OIL is from Jojoba (Jojoba also known as Jojoba, a kind of plant that Mexico is primary Object) in extraction obtain oil.
Wherein, the chemical molecular arrangement of Jojoba Oil is very similar with the sebum of the mankind, belongs to wax quality and on-liquid Quality is easy in by skin and absorption.
By adding ginkgo in substrate oil, the flower bud of lily magnolia, peppermint can be with after the active drug ingredient of rosemary and lemon It in the form of massaging essential oil, is used by specific massage method, there is sensible, the effect of unimpeded respiratory tract that refreshes the mind.
The flower bud of lily magnolia massage oil can be adapted for flu, respiratory tract infection, allergy nasal obstruction, bad, tired, the dizzy brain of memory The big person of swollen and operating pressure applies the efficacy of a drug by modes such as massages, after being absorbed by the body, helps to improve nasal obstruction, giddy Brain is swollen, and pressure is big, the drowsiness and spiritual illnesss such as not good.
In some embodiments, the flower bud of lily magnolia massage oil is mainly by radix bupleuri extract, Radix Astragali extract, rhizoma cyperi extract, river Rhizome of chuanxiong extract, sweet wormwood extract and bergamot extract mix acquisition with the substrate oil by preset adding proportion.Finally Flower bud of lily magnolia massage oil obtained can be closed and be kept in dark place in the containers such as vial to be on the waiting list after quality testing is qualified With.
It is preferred that the biloba extract object, flower bud of lily magnolia extract, peppermint extract, rosemary extract and lemon extraction The adding proportion of object is taken to can control in 2:1:4:4:4 to obtain best treatment, health-care effect.
Specifically, it is based on above-mentioned optimal adding proportion, it by weight, can be in every 100g substrate oil added with as follows Ingredient is to obtain the flower bud of lily magnolia massage oil:
Certainly, which carries out in factory before use, may also pass through the methods of gas-chromatography and mass spectral analysis Detection, determines whether objectionable impurities content is detected or whether can meet preset safety standard, to effectively ensure The quality of flower bud of lily magnolia massage oil.
Flower bud of lily magnolia massage oil is suitable for back fei shu, the massage of air door.In the actual use process, the flower bud of lily magnolia can be used Massage oil massages wing of nose two sides and brows position, to play pure and fresh smooth effect, is conducive to logical nose.The flower bud of lily magnolia is pressed The oil that rubs can also be carried, and by the massage for turning related acupoint point, play the role of refreshing the mind anywhere or anytime.
Usually there is water boiling method for the extracting method of the effective component in Traditional Chinese medicine raw material, infusion process, percolation, change Good gelatin method, circumfluence method and solvent extraction method etc. are several.
For example, solvent extraction method is most widely used method.Its principle is molten according to effective components various in Chinese herbal medicine The property of Xie Du, is selected to needing ingredient solubility big and the solvent small to other compositions solubility, by required activity at Divide and is extracted out of medicinal material tissue.
Steam distillation rule is can be with steam distillation, without the one kind being destroyed using the effective component in Chinese medicine Extracting method.Its extraction for being mainly used for aqua aromatica and volatile oil.The principle of this method is dalton principle --- it is mutually insoluble Also the steam stagnation pressure of chemically inert liquid mixture, equal to the sum of the saturation pressure of each component at this temperature.It is such, to the greatest extent The boiling point of pipe each component itself is higher than the boiling point of mixed liquor, but when dividing summation equal to atmospheric pressure, liquid mixture starts It boils and is distilled off.
Based on one or more kinds of defects or deficiency present in these traditional extracting methods, the embodiment of the present invention Second aspect additionally provides the preparation method of flower bud of lily magnolia massage oil as described above.Fig. 1 is preparation side provided in an embodiment of the present invention The method schematic diagram of method.Fig. 2 is the structural schematic diagram of Preparation equipment provided in an embodiment of the present invention.Based on Fig. 1 and shown in Fig. 2 Preparation method can provide better raw material abstraction efficiency.As depicted in figs. 1 and 2, may include following specific steps:
100, ginkgo, the flower bud of lily magnolia, peppermint, rosemary and lemon raw material are pre-processed.The preprocessing process specifically can basis Actual material characteristic is determined.Such as medicine material biggish for volume, it can carry out being crushed or crushing etc. first pre- Processing operation.
200, by ultrahigh speed vacuum hydro-extraction method, the ginkgo is extracted, the flower bud of lily magnolia, peppermint, in rosemary and lemon raw material Active drug ingredient, obtain corresponding biloba extract object, flower bud of lily magnolia extract, peppermint extract, rosemary extract and lemon Lemon extract.
As shown in Fig. 2, the extraction equipment include: oil pressure cylinder 11, vacuum shell 12, glass visit window 13, cooling device 14, Distilled water storage barrel 15, cooling water radiator 16, revolution pumping 17 and vacuum pump 18.
The extraction process of its ultrahigh speed vacuum hydro-extraction method approximately as: firstly, inside vacuum shell 12 carry out low temperature thickening With the process of low temperature distillation (glass visits window can be to observe the treatment process of raw material) so that effective medicine of traditional Chinese medicinal material raw materials Object ingredient is substantially dissolved in shooting flow body.Then, pressure and temperature is all restored to normal temperature and pressure, enables supercritical fluid extensive It is again gaseous fluid, so that being dissolved in active drug ingredient therein and gaseous fluid quick separating, realizes finally for effective The extraction operation of ingredient.
300, by the biloba extract object, flower bud of lily magnolia extract, peppermint extract, rosemary extract and lemon extract It is added in substrate oil by preset ratio, obtains the flower bud of lily magnolia massage oil.
Specifically, the substrate oil is the high volatile oily liquids that Sweet Almond Oil and SIMMONDSIA CHINENSIS SEED OIL form.It can be adopted It is mixed and is formed with suitable ratio, such as every 100g substrate oil is mixed with 60g Sweet Almond Oil and 40g SIMMONDSIA CHINENSIS SEED OIL.
Preferably, it is also necessary to which detecting the flower bud of lily magnolia massage oil using high performance liquid chromatography chromatography (HPLC) whether there is Excessive harmful substance.If then abandoning and remaking, to ensure that the flower bud of lily magnolia massage oil can be by the use of safety.
Specifically, needing detected harmful substance includes following some projects: organic phosphorus and Carbamates agriculture Medicine residual, borax, formaldehyde, sulfur dioxide, hydrogen peroxide, nitrite, nitrate, sodium formaldehyde sulfoxylate, protein and heavy metal lead.
Certainly, which can also further roll over coloration, rotation brightness, specific gravity, oily oxidant survey after testing The detection such as examination is to ensure the quality of essential oil and meet the standard detection project of inlet and outlet COA.
In conclusion the flower bud of lily magnolia massage oil provided through the embodiment of the present invention combines modern extracting process, Chinese medicine is effective Drug ingedient and the collocation of substrate oil use, and by way of massaging essential oil the effective ingredient of Chinese medicine material are inhaled by stomach The mode of receipts becomes absorbing by skin and smell, it is not easy to there is the problem of harmful substances such as heavy metal etc. are excessively taken in, The quality for being conducive to improve product, meets the requirement of all standard.
The flower bud of lily magnolia massage oil drug effect is significant, and for flu after massage use, respiratory tract infection, allergy nasal obstruction, memory is not It is good, it is tired, it feels dizzy and the big equal patients of operating pressure can play very good health-care effect, there is good application Prospect.
It, can according to the technique and scheme of the present invention and this hair it is understood that for those of ordinary skills Bright design is subject to equivalent substitution or change, and all these changes or replacement all should belong to the guarantor of appended claims of the invention Protect range.

Claims (10)

1. a kind of flower bud of lily magnolia massage oil, which is characterized in that the flower bud of lily magnolia massage oil includes following ingredient: substrate oil, ginkgo, the flower bud of lily magnolia, Peppermint, rosemary and lemon.
2. flower bud of lily magnolia massage oil according to claim 1, which is characterized in that the substrate oil is by Sweet Almond Oil and SIMMONDSIA CHINENSIS SEED OIL It is mixed to form with 3 to 2 weight ratio.
3. flower bud of lily magnolia massage oil according to claim 1, which is characterized in that the flower bud of lily magnolia massage oil is pungent by biloba extract object Smooth extract, peppermint extract, rosemary extract and lemon extract are mixed by preset adding proportion and the substrate oil It closes and obtains.
4. flower bud of lily magnolia massage oil according to claim 3, which is characterized in that the biloba extract object, flower bud of lily magnolia extract, peppermint The adding proportion of extract, rosemary extract and lemon extract is 2:1:4:4:4.
5. flower bud of lily magnolia massage oil according to claim 4, which is characterized in that by weight, in every 100g substrate oil, addition There is following ingredient:
6. a kind of preparation method of flower bud of lily magnolia massage oil, which is characterized in that the preparation method includes:
Pre-process ginkgo, the flower bud of lily magnolia, peppermint, rosemary and lemon raw material;
By ultrahigh speed vacuum hydro-extraction method, the ginkgo is extracted, the flower bud of lily magnolia, peppermint, effective medicine in rosemary and lemon raw material Object ingredient obtains corresponding biloba extract object, flower bud of lily magnolia extract, peppermint extract, rosemary extract and lemon extract;
By the biloba extract object, flower bud of lily magnolia extract, peppermint extract, rosemary extract and lemon extract by default ratio Example is added in substrate oil, obtains the flower bud of lily magnolia massage oil.
7. preparation method according to claim 6, which is characterized in that the ultrahigh speed vacuum hydro-extraction method includes:
In the case where being higher than critical-temperature and pressure, compression fluid is to form supercritical fluid;
Use the active drug ingredient of the supercritical fluid extraction raw material;
Pressure and temperature is all restored to normal temperature and pressure, so that the active drug ingredient is separated with gaseous fluid.
8. preparation method according to claim 6, which is characterized in that the substrate oil is Sweet Almond Oil and SIMMONDSIA CHINENSIS SEED OIL group At high volatile oily liquids.
9. preparation method according to claim 6, which is characterized in that the method also includes: pass through high performance liquid chromatography Chromatography detects whether the flower bud of lily magnolia massage oil meets preset quality standard.
10. application of the flower bud of lily magnolia massage oil a method as claimed in any one of claims 1 to 5 in point massage.
CN201910002708.3A 2019-01-02 2019-01-02 Flower bud of lily magnolia massage oil, preparation method and its application Pending CN109568425A (en)

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Application Number Priority Date Filing Date Title
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Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
海洋之星: "[精油达人讲述]唤醒心底的记忆,迷迭香精油", 《BLOG.SINA.COM.CN/S/BLOG_A667C9DC01015ZW9.HTML》 *

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Application publication date: 20190405