CN109464579A - 一种用于防治鸡球虫病的中药口服液及其制备方法 - Google Patents
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Abstract
一种用于防治鸡球虫病的中药口服液，包括常山、大蒜、柴胡、车前草、黄芩、甘草。本发明中，按计量称取各组分，加水煎煮两次，合并滤液后过滤，滤液浓缩，加入乙醇后静置，过滤后回收乙醇，浓缩，加水定容，冷藏后过滤，加入苯甲酸钠，灌装灭菌后得到成品。使用时按一定比例与水混合，使用时按每公斤体重30毫升的用量，连续服用3～5天后，病鸡精神萎靡、粪便下痢状况明显改善，精神、食欲恢复正常。
Description
技术领域
本发明属于鸡寄生虫疾病防治技术领域，尤其是一种用于防治鸡球虫病的中药口服液及其制备方法。
背景技术
鸡球虫病是由艾美耳球虫属的多种球虫引起的一种寄生虫病，球虫寄生在鸡肠(上皮细胞)内。鸡球虫病在家畜养殖中十分常见，是一种在全球范围内流行的动物疾病，在有高发生率的同时，还有很高的死亡率。
鸡在患了鸡球虫病后，一般会出现精神萎靡、粪便下痢等症状，体内有出血症状。寄生在鸡上皮细胞内的球虫大量繁殖，导致上皮细胞破裂，导致鸡肠内壁出血、发炎，鸡肠内壁黏膜遭到破坏，营养物质吸收功能受阻。另外，在内壁大量出血的情况下会出现机体感染；破裂被分解的上皮细胞会产生有毒物质，进一步加速鸡的病情。
发明内容
本发明的目的在于克服现有技术的不足，提供科学配比、治疗效果好、无毒副作用的一种用于防治鸡球虫病的中药口服液。
本发明采取的技术方案是：一种用于防治仔鸡球虫病的中药口服液，其特征在于：包括按重量份数混合的以下组分：
本发明的另一个目的是提供一种用于防治鸡球虫病的中药口服液的制备方法，其特征在于：包括以下步骤：
⑴按计量称取常山、大蒜、柴胡、车前草、黄芩、甘草，加入10倍重量的清水中煎煮两次；
⑵第一次煎煮2小时后，滤液备用，药渣加入10倍重量的清水进行第二次煎煮，时间为1.5小时，滤液备用；
⑶将两次的滤液合并，过滤后的滤液浓缩至适当，加入乙醇使乙醇含量为75％，搅拌均匀，静置24小时；
⑷将步骤⑶的产物过滤，回收乙醇，浓缩至适量，加水定容，冷藏24小时后过滤，加入苯甲酸钠，灌装灭菌后制得成品。
本发明的另一个目的是提供一种用于防治鸡球虫病的中药口服液的使用方法，其特征在于：将权利要求1或2的药剂喂食病鸡，按每公斤体重30毫升的用量，连续服用3～5天。
本发明的优点和积极效果是：
本发明中，按计量称取常山、大蒜、柴胡、车前草、黄芩、甘草，加水煎煮两次，合并滤液后过滤，滤液浓缩，加入乙醇后静置，过滤后回收乙醇，浓缩，加水定容，冷藏后过滤，加入苯甲酸钠，灌装灭菌后得到成品。使用时按每公斤体重30毫升的用量，连续服用3～5天后，病鸡精神萎靡、粪便下痢状况明显改善，精神、食欲恢复正常。
具体实施方式
下面结合实施例，对本发明进一步说明，下述实施例是说明性的，不是限定性的，不能以下述实施例来限定本发明的保护范围。
一种用于防治鸡球虫病的中药口服液，本发明的创新在于：包括按重量份数混合的以下组分：
更优选的方案是：包括按重量份数混合的以下组分：
本发明药物中：
常山味苦、辛，性寒，可用于截疟杀虫；大蒜具有解毒消肿，杀虫，止痢之功效；柴能够和解表里，疏肝解郁，升阳举陷，退热截疟；车前草具有清热利尿，凉血解毒之功效；黄芩有清热燥湿，泻火解毒功能；甘草具有缓解药物毒性、烈性，调和诸药之功效。
实施例1
用于防治鸡球虫病的中药口服液及制备方法，由下列组分组成：
常山20份、大蒜20份、柴胡10份、车前草5份、黄芩5份、甘草5份
⑴按计量称取常山、大蒜、柴胡、车前草、黄芩、甘草，加入10倍重量的清水中煎煮两次；
⑵第一次煎煮2小时后，滤液备用，药渣加入10倍重量的清水进行第二次煎煮，时间为1.5小时，滤液备用；
⑶将两次的滤液合并，过滤后的滤液浓缩至适当，加入乙醇使乙醇含量为75％，搅拌均匀，静置24小时；
⑷将步骤⑶的产物过滤，回收乙醇，浓缩至适量，加水定容，冷藏24小时后过滤，加入苯甲酸钠，灌装灭菌后制得成品。
实施例2
用于防治鸡球虫病的中药口服液及制备方法，由下列组分组成：
常山20份、大蒜15份、柴胡10份、车前草5份、黄芩5份、甘草5份
上述中药复方制剂其制备方法，按实施例1进行。
实施例3
用于防治鸡球虫病的中药口服液及制备方法，由下列组分组成：
常山15份、大蒜20份、柴胡10份、车前草7份、黄芩7份、甘草5份
上述中药复方制剂其制备方法，按实施例1进行。
实施例4
用于防治鸡球虫病的中药口服液及制备方法，由下列组分组成：
常山20份、大蒜15份、柴胡10份、车前草7份、黄芩7份、甘草5份
上述中药复方制剂其制备方法，按实施例1进行。
临床应用
将本发明药剂饲喂于天津蓟县某鸡场1000只病鸡的治疗(表1)，及北京郊区某鸡场2000只健康鸡的预防(表2)，用药3～5天。结果表明：本发明防治鸡球虫病，有效率和防病率均显著高于药物对照组以及空白对照组(P<0.05)，病情得到控制，未再出现腹泻、精神不振现象。
表1治疗组用药结果
| 组别 | 病例数 | 有效数 | 有效率％ | 无效数 | 无效率％ |
| 试验组 | 1400 | 1396 | 99.7 | 4 | 0.3 |
| 药物对照组 | 1400 | 1331 | 95.1 | 69 | 4.9 |
| 空白对照组 | 200 | 2 | 0.1 | 198 | 99.9 |
表2预防组用药结果
| 组别 | 试验总数 | 发病数 | 发病率％ | 未发病数 | 预防率％ |
| 试验组 | 1000 | 21 | 2.1 | 979 | 97.9 |
| 空白对照组 | 1000 | 426 | 42.6 | 574 | 57.4 |
Claims (4)
1.一种用于防治鸡球虫病的中药口服液，其特征在于：包括按重量份数混合的以下组分：
2.根据权利要求1所述的一种用于防治鸡球虫病的中药口服液，其特征在于：包括按重量份数混合的以下组分：
3.根据权利要求1或2所述的一种用于防治鸡球虫病的中药口服液，其特征在于：包括以下步骤：
⑴按计量称取常山、大蒜、柴胡、车前草、黄芩、甘草，加入10倍重量的清水中煎煮两次；
⑵第一次煎煮2小时后，滤液备用，药渣加入10倍重量的清水进行第二次煎煮，时间为1.5小时，滤液备用；
⑶将两次的滤液合并，过滤后的滤液浓缩至适当，加入乙醇使乙醇含量为75％，搅拌均匀，静置24小时；
⑷将步骤⑶的产物过滤，回收乙醇，浓缩至适量，加水定容，冷藏24小时后过滤，加入苯甲酸钠，灌装灭菌后制得成品。
4.一种用于防治鸡球虫病的中药口服液，其特征在于：将权利要求1或2的药剂使用时按每公斤体重30毫升的用量，连续服用3～5天。
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| CN112933172A (zh) * | 2021-04-13 | 2021-06-11 | 四川省畜牧科学研究院 | 一种治疗兔肠道球虫病的中药复方提取物及其用途 |
| CN112933172B (zh) * | 2021-04-13 | 2022-05-06 | 四川省畜牧科学研究院 | 一种治疗兔肠道球虫病的中药复方提取物及其用途 |
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