CN109464362A - A kind of sea-buckthorn beauty mud and preparation method with lasting skin whitening, moisturizing effect - Google Patents

A kind of sea-buckthorn beauty mud and preparation method with lasting skin whitening, moisturizing effect Download PDF

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CN109464362A
CN109464362A CN201811458055.1A CN201811458055A CN109464362A CN 109464362 A CN109464362 A CN 109464362A CN 201811458055 A CN201811458055 A CN 201811458055A CN 109464362 A CN109464362 A CN 109464362A
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赵宏伟
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/00—Cosmetics or similar toiletry preparations
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    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract

The present invention relates to the technical fields of beauty product, provide a kind of sea-buckthorn beauty mud and preparation method with lasting skin whitening, moisturizing effect.This method, which loads Hippophae Rhamnoides L. juice with jellyfish dry powder and coats perillaldehyde, is made sea-buckthorn compound A, Hippophae Rhamnoides L. juice is loaded with the Composite Shell powder of shrimp shell, crab shell and sea-buckthorn compound B is made in hyaluronic acid, then sea-buckthorn compound A, sea-buckthorn compound B, ginkgo biloba p.e, bamboo extractive, bamboo charcoal powder, lecithin, talcum powder, glycerol, seaweed glue, hydroxyethyl cellulose, deionized water are kneaded as pureed, a kind of sea-buckthorn beauty mud with lasting skin whitening, moisturizing effect is made.It is compared with the traditional method, preparation method of the invention can not only effectively prevent the isolation of active seabuckthorn ingredient, but also solve not deep, the unabiding defect of active seabuckthorn ingredient effect.

Description

A kind of sea-buckthorn beauty mud and preparation method with lasting skin whitening, moisturizing effect
Technical field
The invention belongs to the technical fields of beauty product, provide a kind of sea-buckthorn beauty with lasting skin whitening, moisturizing effect Mud and preparation method.
Background technique
Beauty product mainly has two major classes: one is chemical products；One is biological species products.And in chemical product The chemical additives such as emulsifier, fragrance, pigment, preservative easily cause a degree of injury to user, and biological species produce Product have more humanized characteristic, and raw material mainly extracts from animals and plants, with high-tech means, animals and plants essence is answered Miscellaneous extraction reaches the health and beauty purpose for the treatment of both manifestation and root cause of disease by the reparation and maintenance to human body viscera cell physiological function, because And become the Developing mainstream of beauty product.
Sea-buckthorn is a kind of common medicinal and edible plant, and the root of sea-buckthorn, stem, leaf, flower, fruit, especially sea buckthorn fruit contain Nutriment and bioactive substance abundant, the raw material as biological species cosmetics, receives more and more attention in recent years.
A variety of amino acid, multivitamin, microelement, unsaturated fatty acid, SOD that sea-buckthorn contains etc. is to preventing skin Aging, desalination senile plaque, chloasma, improvement sleep quality, raising memory, holding vigorous energy and physical strength have good Effect；Effect Cucumber Extract can be inhaled, cell metabolism is promoted, promotes epithelial tissue regeneration, prevents melanin production；Contain super oxygen discrimination Change enzyme, can blocking oxide, eliminate interior free yl delaying human body caducity.Ultraviolet light is resisted with antiallergy, antibacterial, help skin Infringement and other effects.Therefore, sea-buckthorn is in skin whitening, moisturizing product using more and more.
However, the cosmetics of the existing ingredient containing sea-buckthorn usually active ingredient easily isolate, act on do not go deep into it is unabiding Defect constrains sea-buckthorn in the development and application in beauty product field.Therefore, develop a kind of active constituent it is stable, can percdation And the sea-buckthorn beauty product that effectiveness is lasting, it has great significance.
Summary of the invention
Usually active ingredient easily isolates, acts on and do not go deep into unabiding defect the cosmetics of the existing ingredient containing sea-buckthorn. In response to this, the present invention proposes a kind of sea-buckthorn beauty mud and preparation method with lasting skin whitening, moisturizing effect, can both have Effect prevents the isolation of active seabuckthorn ingredient, and solves not deep, the unabiding defect of active seabuckthorn ingredient effect.
To achieve the above object, specific technical solution of the present invention is as follows:
A kind of preparation method of the sea-buckthorn beauty mud with lasting skin whitening, moisturizing effect, the clay standby specific step of sea-buckthorn beauty It is rapid as follows:
(1) it takes fresh fructus hippophae to clean, squeezes the juice at normal temperature, gained Hippophae Rhamnoides L. juice is divided into two parts of A, B；
(2) fresh jellyfish is dried, crushing in airflow machine is nanoscale dry powder, is added in Hippophae Rhamnoides L. juice A, it is sufficiently mixed uniformly, It immerses Hippophae Rhamnoides L. juice in the natural micropore of jellyfish dry powder, then carries out atomizing freeze drying, then perillaldehyde is dissolved in ethyl alcohol, spray Mist is deposited on dry powder surface, and sea-buckthorn compound A is made；
(3) shrimp shell, crab shell are cleaned and is crushed, be subsequently placed in ball mill and carry out wet grinding, through being dried to obtain nanoscale Composite Shell powder is added in the mixed liquor of Hippophae Rhamnoides L. juice B, hyaluronic acid, is sufficiently mixed uniformly, is carried on Hippophae Rhamnoides L. juice and hyaluronic acid In the natural micropore of Composite Shell powder, atomizing freeze drying is then carried out, sea-buckthorn compound B is made；
(4) by sea-buckthorn compound A, sea-buckthorn compound B, ginkgo biloba p.e, bamboo extractive, bamboo charcoal powder, lecithin, talcum Powder, glycerol, seaweed glue, hydroxyethyl cellulose, deionized water mixing, are kneaded as pureed, being made has lasting skin whitening, moisturizing effect Sea-buckthorn beauty mud.
Preferably, the weight ratio of step (1) two parts of Hippophae Rhamnoides L. juices of A, B is 1:2 ~ 2:1.
Preferably, the average grain diameter of step (2) the nanoscale jellyfish dry powder is 50 ~ 200nm.
Preferably, step (2) incorporation time is 60 ~ 90min.
Preferably, the parts by weight of step (2) each raw material are 20 ~ 30 parts by weight of jellyfish dry powder, Hippophae Rhamnoides L. juice A 30 ~ 55 Parts by weight, 5 ~ 10 parts by weight of perillaldehyde, 20 ~ 30 parts by weight of ethyl alcohol.
Preferably, the average grain diameter of step (3) the nanoscale Composite Shell powder is 100 ~ 300nm.
Preferably, step (3) incorporation time is 30 ~ 60min.
Preferably, the parts by weight of step (3) each raw material are 12 ~ 18 parts by weight of shrimp shell, 12 ~ 18 parts by weight of crab shell, sand 62 ~ 75 parts by weight of spine juice B, 1 ~ 2 parts by weight of hyaluronic acid.
Preferably, the parts by weight of step (4) each raw material are 22 ~ 25 parts by weight of sea-buckthorn compound A, sea-buckthorn compound 15 ~ 18 parts by weight of B, 3 ~ 5 parts by weight of ginkgo biloba p.e, 3 ~ 5 parts by weight of bamboo extractive, 2 ~ 4 parts by weight of bamboo charcoal powder, lecithin 1 ~ 2 parts by weight of rouge, 2 ~ 4 parts by weight of talcum powder, 1 ~ 2 parts by weight of glycerol, 2 ~ 3 parts by weight of seaweed glue, 1 ~ 2 weight of hydroxyethyl cellulose Part, 28 ~ 46 parts by weight of deionized water.
General extraction methods preparation can be used in the above-mentioned ginkgo biloba p.e being related to: ginkgo leaf is cleaned, is dry, milling, It is added in ethyl alcohol or n-butanol, 70 ~ 75 DEG C, 30 ~ 40min of refluxing extraction is heated under stirring, extracting solution is filtered, is dense Contracting, vacuum drying, can be prepared by.
General extraction methods preparation can be used in the above-mentioned bamboo extractive being related to: the leaf of bamboo being cleaned, is dry, milling, is added In ethyl acetate, 60 ~ 70 DEG C of 2 ~ 3h of extraction are heated to, filtering, concentration, vacuum drying can be prepared by.
The present invention also provides a kind of sand with lasting skin whitening, moisturizing effect that a kind of above-mentioned preparation method is prepared Spine beauty mud.The sea-buckthorn beauty mud is that sea-buckthorn compound A is made by loading Hippophae Rhamnoides L. juice with jellyfish dry powder and coating perillaldehyde, Hippophae Rhamnoides L. juice is loaded with the Composite Shell powder of shrimp shell, crab shell and sea-buckthorn compound B is made in hyaluronic acid, then by sea-buckthorn compound A, sand Spine compound B, ginkgo biloba p.e, bamboo extractive, bamboo charcoal powder, lecithin, talcum powder, glycerol, seaweed glue, hydroxy ethyl fiber Element, deionized water are kneaded as pureed and are made.
The present invention provides a kind of sea-buckthorn beauty mud and preparation method with lasting skin whitening, moisturizing effect, with the prior art It compares, the feature and excellent effect protruded is:
1. preparation method of the invention, the Composite Shell powder that jellyfish dry powder and shrimp shell, crab shell is respectively adopted loads Hippophae Rhamnoides L. juice, It can effectively prevent the isolation of active seabuckthorn ingredient.
2. preparation method of the invention when being loaded with jellyfish dry powder to Hippophae Rhamnoides L. juice, is promoted by the effect of perillaldehyde The percdation of jellyfish dry powder and sea-buckthorn ingredient keeps the effective component (amino acid, vitamin, microelement, SOD etc.) of sea-buckthorn deep Enter inside skin, promote cell metabolism, prevent melanin production, helps skin to resist ultraviolet light, reach whitening effect；Meanwhile The percdation of jellyfish dry powder can reach moistening effect and prevent the loss of Effective Compositions of Seabuckthorn in deep skin depth water lock. By this method, solves active seabuckthorn ingredient and act on not deep defect.
3. preparation method of the invention, when being loaded with the Composite Shell powder of shrimp shell, crab shell to Hippophae Rhamnoides L. juice, hyaluronic acid, Since the load of sea-buckthorn ingredient and hyaluronic acid in Composite Shell powder is more stable persistently, it can be achieved that slow release, is conducive to maintain The concentration of active seabuckthorn ingredient and the moisturizing factor is stablized in skin, and extends effective acting time, to solve active seabuckthorn Ingredient acts on unabiding defect.
4. in sea-buckthorn beauty mud prepared by the present invention, the ginkgo biloba p.e of addition has very strong free radical scavenging ability And oxidation resistance, have the function of delaying senescence；The bamboo extractive of addition may advantageously facilitate telangiectasis, improve skin Skin microcirculation promotes the exclusion of pigment etc.；The bamboo charcoal powder of addition has good adsorption capacity, can help to remove in skin pore Rubbish.
Specific embodiment
In the following, the present invention will be further described in detail by way of specific embodiments, but this should not be interpreted as to the present invention Range be only limitted to example below.Without departing from the idea of the above method of the present invention, according to ordinary skill The various replacements or change that knowledge and customary means are made, should be included in the scope of the present invention.
Embodiment 1
(1) it takes fresh fructus hippophae to clean, squeezes the juice at normal temperature, gained Hippophae Rhamnoides L. juice is divided into two parts of A, B；A, B two parts of Hippophae Rhamnoides L. juices Weight ratio is 1:1；
(2) fresh jellyfish is dried, crushing in airflow machine is nanoscale dry powder, is added in Hippophae Rhamnoides L. juice A, it is sufficiently mixed uniformly, It immerses Hippophae Rhamnoides L. juice in the natural micropore of jellyfish dry powder, then carries out atomizing freeze drying, then perillaldehyde is dissolved in ethyl alcohol, spray Mist is deposited on dry powder surface, and sea-buckthorn compound A is made；The average grain diameter of nanoscale jellyfish dry powder is 90nm；Incorporation time is 70min；The parts by weight of each raw material are 24 parts by weight of jellyfish dry powder, 45 parts by weight of Hippophae Rhamnoides L. juice A, 7 parts by weight of perillaldehyde, ethyl alcohol 24 Parts by weight；
(3) shrimp shell, crab shell are cleaned and is crushed, be subsequently placed in ball mill and carry out wet grinding, through being dried to obtain nanoscale Composite Shell powder is added in the mixed liquor of Hippophae Rhamnoides L. juice B, hyaluronic acid, is sufficiently mixed uniformly, then carries out atomizing freeze drying, makes Obtain sea-buckthorn compound B；The average grain diameter of nanoscale Composite Shell powder is 180nm；Incorporation time is 50min；The parts by weight of each raw material For 14 parts by weight of shrimp shell, 14 parts by weight of crab shell, 70 parts by weight of Hippophae Rhamnoides L. juice B, 2 parts by weight of hyaluronic acid；
(4) by sea-buckthorn compound A, sea-buckthorn compound B, ginkgo biloba p.e, bamboo extractive, bamboo charcoal powder, lecithin, talcum Powder, glycerol, seaweed glue, hydroxyethyl cellulose, deionized water mixing, are kneaded as pureed, being made has lasting skin whitening, moisturizing effect Sea-buckthorn beauty mud；The parts by weight of each raw material are 23 parts by weight of sea-buckthorn compound A, 17 parts by weight of sea-buckthorn compound B, ginkgo 4 parts by weight of leaf extract, 4 parts by weight of bamboo extractive, 3 parts by weight of bamboo charcoal powder, 1 parts by weight of lecithin, 3 parts by weight of talcum powder, 1 parts by weight of glycerol, 3 parts by weight of seaweed glue, 1 parts by weight of hydroxyethyl cellulose, 38 parts by weight of deionized water；
The extracting method of ginkgo biloba p.e are as follows: ginkgo leaf is cleaned, is dry, milling, is added in ethyl alcohol, is heated under stirring To 73 DEG C, refluxing extraction 34min, extracting solution is filtered, concentration, vacuum drying, be can be prepared by；The extracting method of bamboo extractive Are as follows: the leaf of bamboo is cleaned, is dry, milling, is added in ethyl acetate, 66 DEG C of extraction 2.5h are heated to, is filtered, concentration, vacuum drying, It can be prepared by.
Embodiment 2
(1) it takes fresh fructus hippophae to clean, squeezes the juice at normal temperature, gained Hippophae Rhamnoides L. juice is divided into two parts of A, B；A, B two parts of Hippophae Rhamnoides L. juices Weight ratio is 1:2；
(2) fresh jellyfish is dried, crushing in airflow machine is nanoscale dry powder, is added in Hippophae Rhamnoides L. juice A, it is sufficiently mixed uniformly, It immerses Hippophae Rhamnoides L. juice in the natural micropore of jellyfish dry powder, then carries out atomizing freeze drying, then perillaldehyde is dissolved in ethyl alcohol, spray Mist is deposited on dry powder surface, and sea-buckthorn compound A is made；The average grain diameter of nanoscale jellyfish dry powder is 70nm；Incorporation time is 70min；The parts by weight of each raw material are 22 parts by weight of jellyfish dry powder, 49 parts by weight of Hippophae Rhamnoides L. juice A, 7 parts by weight of perillaldehyde, ethyl alcohol 22 Parts by weight；
(3) shrimp shell, crab shell are cleaned and is crushed, be subsequently placed in ball mill and carry out wet grinding, through being dried to obtain nanoscale Composite Shell powder is added in the mixed liquor of Hippophae Rhamnoides L. juice B, hyaluronic acid, is sufficiently mixed uniformly, then carries out atomizing freeze drying, makes Obtain sea-buckthorn compound B；The average grain diameter of nanoscale Composite Shell powder is 150nm；Incorporation time is 40min；The parts by weight of each raw material For 13 parts by weight of shrimp shell, 13 parts by weight of crab shell, 73 parts by weight of Hippophae Rhamnoides L. juice B, 1 parts by weight of hyaluronic acid；
(4) by sea-buckthorn compound A, sea-buckthorn compound B, ginkgo biloba p.e, bamboo extractive, bamboo charcoal powder, lecithin, talcum Powder, glycerol, seaweed glue, hydroxyethyl cellulose, deionized water mixing, are kneaded as pureed, being made has lasting skin whitening, moisturizing effect Sea-buckthorn beauty mud；The parts by weight of each raw material are 23 parts by weight of sea-buckthorn compound A, 16 parts by weight of sea-buckthorn compound B, ginkgo 3 parts by weight of leaf extract, 4 parts by weight of bamboo extractive, 2 parts by weight of bamboo charcoal powder, 1 parts by weight of lecithin, 3 parts by weight of talcum powder, 1 parts by weight of glycerol, 2 parts by weight of seaweed glue, 1 parts by weight of hydroxyethyl cellulose, 42 parts by weight of deionized water；
The extracting method of ginkgo biloba p.e are as follows: ginkgo leaf is cleaned, is dry, milling, is added in n-butanol, is added under stirring Extracting solution is filtered, concentration, vacuum drying, be can be prepared by 71 DEG C, refluxing extraction 38min by heat；The extraction side of bamboo extractive Method are as follows: the leaf of bamboo is cleaned, is dry, milling, is added in ethyl acetate, 62 DEG C of extraction 3h are heated to, is filtered, concentration, vacuum drying, It can be prepared by.
Embodiment 3
(1) it takes fresh fructus hippophae to clean, squeezes the juice at normal temperature, gained Hippophae Rhamnoides L. juice is divided into two parts of A, B；A, B two parts of Hippophae Rhamnoides L. juices Weight ratio is 2:1；
(2) fresh jellyfish is dried, crushing in airflow machine is nanoscale dry powder, is added in Hippophae Rhamnoides L. juice A, it is sufficiently mixed uniformly, It immerses Hippophae Rhamnoides L. juice in the natural micropore of jellyfish dry powder, then carries out atomizing freeze drying, then perillaldehyde is dissolved in ethyl alcohol, spray Mist is deposited on dry powder surface, and sea-buckthorn compound A is made；The average grain diameter of nanoscale jellyfish dry powder is 150nm；Incorporation time is 80min；The parts by weight of each raw material are 27 parts by weight of jellyfish dry powder, 38 parts by weight of Hippophae Rhamnoides L. juice A, 8 parts by weight of perillaldehyde, ethyl alcohol 27 Parts by weight；
(3) shrimp shell, crab shell are cleaned and is crushed, be subsequently placed in ball mill and carry out wet grinding, through being dried to obtain nanoscale Composite Shell powder is added in the mixed liquor of Hippophae Rhamnoides L. juice B, hyaluronic acid, is sufficiently mixed uniformly, then carries out atomizing freeze drying, makes Obtain sea-buckthorn compound B；The average grain diameter of nanoscale Composite Shell powder is 250nm；Incorporation time is 50min；The parts by weight of each raw material For 16 parts by weight of shrimp shell, 16 parts by weight of crab shell, 66 parts by weight of Hippophae Rhamnoides L. juice B, 2 parts by weight of hyaluronic acid；
(4) by sea-buckthorn compound A, sea-buckthorn compound B, ginkgo biloba p.e, bamboo extractive, bamboo charcoal powder, lecithin, talcum Powder, glycerol, seaweed glue, hydroxyethyl cellulose, deionized water mixing, are kneaded as pureed, being made has lasting skin whitening, moisturizing effect Sea-buckthorn beauty mud；The parts by weight of each raw material are 24 parts by weight of sea-buckthorn compound A, 17 parts by weight of sea-buckthorn compound B, ginkgo 4 parts by weight of leaf extract, 5 parts by weight of bamboo extractive, 3 parts by weight of bamboo charcoal powder, 2 parts by weight of lecithin, 3 parts by weight of talcum powder, 2 parts by weight of glycerol, 3 parts by weight of seaweed glue, 2 parts by weight of hydroxyethyl cellulose, 33 parts by weight of deionized water；
The extracting method of ginkgo biloba p.e are as follows: ginkgo leaf is cleaned, is dry, milling, is added in ethyl alcohol, is heated under stirring To 74 DEG C, refluxing extraction 37min, extracting solution is filtered, concentration, vacuum drying, be can be prepared by；The extracting method of bamboo extractive Are as follows: the leaf of bamboo is cleaned, is dry, milling, is added in ethyl acetate, 67 DEG C of extraction 2h are heated to, is filtered, concentration, vacuum drying, i.e., It can be made.
Embodiment 4
(1) it takes fresh fructus hippophae to clean, squeezes the juice at normal temperature, gained Hippophae Rhamnoides L. juice is divided into two parts of A, B；A, B two parts of Hippophae Rhamnoides L. juices Weight ratio is 1:2；
(2) fresh jellyfish is dried, crushing in airflow machine is nanoscale dry powder, is added in Hippophae Rhamnoides L. juice A, it is sufficiently mixed uniformly, It immerses Hippophae Rhamnoides L. juice in the natural micropore of jellyfish dry powder, then carries out atomizing freeze drying, then perillaldehyde is dissolved in ethyl alcohol, spray Mist is deposited on dry powder surface, and sea-buckthorn compound A is made；The average grain diameter of nanoscale jellyfish dry powder is 50nm；Incorporation time is 60min；The parts by weight of each raw material are 20 parts by weight of jellyfish dry powder, 55 parts by weight of Hippophae Rhamnoides L. juice A, 5 parts by weight of perillaldehyde, ethyl alcohol 20 Parts by weight；
(3) shrimp shell, crab shell are cleaned and is crushed, be subsequently placed in ball mill and carry out wet grinding, through being dried to obtain nanoscale Composite Shell powder is added in the mixed liquor of Hippophae Rhamnoides L. juice B, hyaluronic acid, is sufficiently mixed uniformly, then carries out atomizing freeze drying, makes Obtain sea-buckthorn compound B；The average grain diameter of nanoscale Composite Shell powder is 100nm；Incorporation time is 30min；The parts by weight of each raw material For 12 parts by weight of shrimp shell, 12 parts by weight of crab shell, 75 parts by weight of Hippophae Rhamnoides L. juice B, 1 parts by weight of hyaluronic acid；
(4) by sea-buckthorn compound A, sea-buckthorn compound B, ginkgo biloba p.e, bamboo extractive, bamboo charcoal powder, lecithin, talcum Powder, glycerol, seaweed glue, hydroxyethyl cellulose, deionized water mixing, are kneaded as pureed, being made has lasting skin whitening, moisturizing effect Sea-buckthorn beauty mud；The parts by weight of each raw material are 22 parts by weight of sea-buckthorn compound A, 15 parts by weight of sea-buckthorn compound B, ginkgo 3 parts by weight of leaf extract, 3 parts by weight of bamboo extractive, 2 parts by weight of bamboo charcoal powder, 1 parts by weight of lecithin, 2 parts by weight of talcum powder, 1 parts by weight of glycerol, 2 parts by weight of seaweed glue, 1 parts by weight of hydroxyethyl cellulose, 46 parts by weight of deionized water；
The extracting method of ginkgo biloba p.e are as follows: ginkgo leaf is cleaned, is dry, milling, is added in n-butanol, is added under stirring Extracting solution is filtered, concentration, vacuum drying, be can be prepared by 70 DEG C, refluxing extraction 40min by heat；The extraction side of bamboo extractive Method are as follows: the leaf of bamboo is cleaned, is dry, milling, is added in ethyl acetate, 60 DEG C of extraction 3h are heated to, is filtered, concentration, vacuum drying, It can be prepared by.
Embodiment 5
(1) it takes fresh fructus hippophae to clean, squeezes the juice at normal temperature, gained Hippophae Rhamnoides L. juice is divided into two parts of A, B；A, B two parts of Hippophae Rhamnoides L. juices Weight ratio is 2:1；
(2) fresh jellyfish is dried, crushing in airflow machine is nanoscale dry powder, is added in Hippophae Rhamnoides L. juice A, it is sufficiently mixed uniformly, It immerses Hippophae Rhamnoides L. juice in the natural micropore of jellyfish dry powder, then carries out atomizing freeze drying, then perillaldehyde is dissolved in ethyl alcohol, spray Mist is deposited on dry powder surface, and sea-buckthorn compound A is made；The average grain diameter of nanoscale jellyfish dry powder is 200nm；Incorporation time is 90min；The parts by weight of each raw material are 30 parts by weight of jellyfish dry powder, 30 parts by weight of Hippophae Rhamnoides L. juice A, 10 parts by weight of perillaldehyde, ethyl alcohol 30 parts by weight；
(3) shrimp shell, crab shell are cleaned and is crushed, be subsequently placed in ball mill and carry out wet grinding, through being dried to obtain nanoscale Composite Shell powder is added in the mixed liquor of Hippophae Rhamnoides L. juice B, hyaluronic acid, is sufficiently mixed uniformly, then carries out atomizing freeze drying, makes Obtain sea-buckthorn compound B；The average grain diameter of nanoscale Composite Shell powder is 300nm；Incorporation time is 60min；The parts by weight of each raw material For 18 parts by weight of shrimp shell, 18 parts by weight of crab shell, 62 parts by weight of Hippophae Rhamnoides L. juice B, 2 parts by weight of hyaluronic acid；
(4) by sea-buckthorn compound A, sea-buckthorn compound B, ginkgo biloba p.e, bamboo extractive, bamboo charcoal powder, lecithin, talcum Powder, glycerol, seaweed glue, hydroxyethyl cellulose, deionized water mixing, are kneaded as pureed, being made has lasting skin whitening, moisturizing effect Sea-buckthorn beauty mud；The parts by weight of each raw material are 25 parts by weight of sea-buckthorn compound A, 18 parts by weight of sea-buckthorn compound B, ginkgo 5 parts by weight of leaf extract, 5 parts by weight of bamboo extractive, 4 parts by weight of bamboo charcoal powder, 2 parts by weight of lecithin, 4 parts by weight of talcum powder, 2 parts by weight of glycerol, 3 parts by weight of seaweed glue, 2 parts by weight of hydroxyethyl cellulose, 28 parts by weight of deionized water；
The extracting method of ginkgo biloba p.e are as follows: ginkgo leaf is cleaned, is dry, milling, is added in ethyl alcohol, is heated under stirring To 75 DEG C, refluxing extraction 30min, extracting solution is filtered, concentration, vacuum drying, be can be prepared by；The extracting method of bamboo extractive Are as follows: the leaf of bamboo is cleaned, is dry, milling, is added in ethyl acetate, 70 DEG C of extraction 2h are heated to, is filtered, concentration, vacuum drying, i.e., It can be made.
Embodiment 6
(1) it takes fresh fructus hippophae to clean, squeezes the juice at normal temperature, gained Hippophae Rhamnoides L. juice is divided into two parts of A, B；A, B two parts of Hippophae Rhamnoides L. juices Weight ratio is 1:1；
(2) fresh jellyfish is dried, crushing in airflow machine is nanoscale dry powder, is added in Hippophae Rhamnoides L. juice A, it is sufficiently mixed uniformly, It immerses Hippophae Rhamnoides L. juice in the natural micropore of jellyfish dry powder, then carries out atomizing freeze drying, then perillaldehyde is dissolved in ethyl alcohol, spray Mist is deposited on dry powder surface, and sea-buckthorn compound A is made；The average grain diameter of nanoscale jellyfish dry powder is 120nm；Incorporation time is 75min；The parts by weight of each raw material are 25 parts by weight of jellyfish dry powder, 42 parts by weight of Hippophae Rhamnoides L. juice A, 8 parts by weight of perillaldehyde, ethyl alcohol 25 Parts by weight；
(3) shrimp shell, crab shell are cleaned and is crushed, be subsequently placed in ball mill and carry out wet grinding, through being dried to obtain nanoscale Composite Shell powder is added in the mixed liquor of Hippophae Rhamnoides L. juice B, hyaluronic acid, is sufficiently mixed uniformly, then carries out atomizing freeze drying, makes Obtain sea-buckthorn compound B；The average grain diameter of nanoscale Composite Shell powder is 200nm；Incorporation time is 45min；The parts by weight of each raw material For 15 parts by weight of shrimp shell, 15 parts by weight of crab shell, 69 parts by weight of Hippophae Rhamnoides L. juice B, 1 parts by weight of hyaluronic acid；
(4) by sea-buckthorn compound A, sea-buckthorn compound B, ginkgo biloba p.e, bamboo extractive, bamboo charcoal powder, lecithin, talcum Powder, glycerol, seaweed glue, hydroxyethyl cellulose, deionized water mixing, are kneaded as pureed, being made has lasting skin whitening, moisturizing effect Sea-buckthorn beauty mud；The parts by weight of each raw material are 24 parts by weight of sea-buckthorn compound A, 16 parts by weight of sea-buckthorn compound B, ginkgo 4 parts by weight of leaf extract, 4 parts by weight of bamboo extractive, 3 parts by weight of bamboo charcoal powder, 1 parts by weight of lecithin, 3 parts by weight of talcum powder, 2 parts by weight of glycerol, 3 parts by weight of seaweed glue, 1 parts by weight of hydroxyethyl cellulose, 37 parts by weight of deionized water；
The extracting method of ginkgo biloba p.e are as follows: ginkgo leaf is cleaned, is dry, milling, is added in n-butanol, is added under stirring Extracting solution is filtered, concentration, vacuum drying, be can be prepared by 72 DEG C, refluxing extraction 35min by heat；The extraction side of bamboo extractive Method are as follows: the leaf of bamboo is cleaned, is dry, milling, is added in ethyl acetate, 65 DEG C of extraction 2.5h are heated to, filtering, concentration, vacuum are dry It is dry, it can be prepared by.
Comparative example 1
In preparation process, Hippophae Rhamnoides L. juice is loaded only with jellyfish dry powder, does not use the Composite Shell powder of shrimp shell, crab shell to sea-buckthorn Juice is loaded, other preparation conditions and embodiment 6 are consistent.
Comparative example 2
In preparation process, Hippophae Rhamnoides L. juice is loaded only with the Composite Shell powder of shrimp shell, crab shell, not using jellyfish dry powder to sea-buckthorn Juice is loaded, and is not added with perillaldehyde, other preparation conditions and embodiment 6 are consistent.
Performance test:
(1) transdermal test in vitro drug release amount: cavy being put to death, shaving, is removed skin of abdomen, is shaved fat deposit with dermatotome, with life It is fixed on the pond single chamber Franz after reason salt water repeated flushing, skin corium is towards reception medium；By sea-buckthorn beauty produced by the present invention For mud even application on isolated skin cuticula, reception medium is 30% volume fraction PEG400 aqueous solution 100mL；The pond Franz temperature Degree is set as (32 ± 0.5) DEG C, and magnetic stirring speed is set as 120r/min；Receiving liquid sample is taken when 4h, 8h and 12h Product, and Fresh receiving liquid is supplemented, using the Effective Compositions of Seabuckthorn content for taking out sample is tested with high performance liquid chromatograph, count Calculate transdermal test in vitro drug release amount；
(2) hydration status value: selection healthy volunteer 30, male 15, women 15, the age at 30 ~ 60 years old, owns For subject without any skin or systemic disease history, recipient site (inboard arm) skin is without exception, does not also smear any external application The external preparations such as drug and cosmetics；Test environment temperature remains (22 ± 1) DEG C, and relative humidity remains 50 ± 5%, test Preceding volunteer need to enter test environment, rest 30min(shell temperature, the temporary skin such as mood, sweat and fat secretion in advance State reaches unified)；Select the left and right inboard arm of subject away from palm base portion 5cm at；It is identical that several areas are defined in left forearm Region (4cm × 4cm) be used as using area；The point of right forearm same position is as blank control region, pair of left and right forearm It answers region while testing；Sample (about 1.5 μ g/cm are smeared in arm Experimental Area in subject2)；1h, 2h, 4h after smearing And 8h is measured 5 times using the hydration status of CorneometerCM825 test skin, is obtained 5 measurement numerical value, and be averaged Value；Blank value is the average value of the 5 hydration status relative values measured at the 0h moment；30 subjects are smeared into same sample When the data that measure be averaged；
(3) dark red pigment reduced rate: selection healthy volunteer 30, male 15, women 15, the age at 30 ~ 60 years old, For all subjects without any skin or systemic disease history, recipient site (inboard arm) skin is without exception, does not also smear any The external preparations such as external drug and cosmetics；Test environment temperature remains (22 ± 1) DEG C, and relative humidity remains 50 ± 5%, Volunteer need to enter test environment in advance before testing, and rest 30min(shell temperature, mood, sweat and fat secretion etc. are temporary Skin condition reaches unified)；Select the left and right inboard arm of subject away from palm base portion 5cm at；Several areas are defined in left forearm Identical region (4cm × 4cm) is used as using area；The point of right forearm same position is as blank control region, left and right forearm Corresponding region test simultaneously；Melanin and haematochrome are tested using 18 VISIA digital skin tester of Mexameter MX Then initial value smears sample (about 1.5 μ g/cm in arm Experimental Area in subject2), 2 times a day；Then respectively at 2 Melanin value and red pigment value are tested when week, 4 weeks and 8 weeks again, calculates melanin and the total reduced rate of haematochrome.
The data obtained is as shown in table 1.
Table 1:

Claims (10)

1. a kind of preparation method of the sea-buckthorn beauty mud with lasting skin whitening, moisturizing effect, which is characterized in that the sea-buckthorn beauty It is clay that standby specific step is as follows:
(1) it takes fresh fructus hippophae to clean, squeezes the juice at normal temperature, gained Hippophae Rhamnoides L. juice is divided into two parts of A, B；
(2) fresh jellyfish is dried, crushing in airflow machine is nanoscale dry powder, is added in Hippophae Rhamnoides L. juice A, it is sufficiently mixed uniformly, It immerses Hippophae Rhamnoides L. juice in the natural micropore of jellyfish dry powder, then carries out atomizing freeze drying, then perillaldehyde is dissolved in ethyl alcohol, spray Mist is deposited on dry powder surface, and sea-buckthorn compound A is made；
(3) shrimp shell, crab shell are cleaned and is crushed, be subsequently placed in ball mill and carry out wet grinding, through being dried to obtain nanoscale Composite Shell powder is added in the mixed liquor of Hippophae Rhamnoides L. juice B, hyaluronic acid, is sufficiently mixed uniformly, is carried on Hippophae Rhamnoides L. juice and hyaluronic acid In the natural micropore of Composite Shell powder, atomizing freeze drying is then carried out, sea-buckthorn compound B is made；
(4) by sea-buckthorn compound A, sea-buckthorn compound B, ginkgo biloba p.e, bamboo extractive, bamboo charcoal powder, lecithin, talcum Powder, glycerol, seaweed glue, hydroxyethyl cellulose, deionized water mixing, are kneaded as pureed, being made has lasting skin whitening, moisturizing effect Sea-buckthorn beauty mud.
2. a kind of preparation method of the sea-buckthorn beauty mud with lasting skin whitening, moisturizing effect according to claim 1, feature Be: the weight ratio of step (1) two parts of Hippophae Rhamnoides L. juices of A, B is 1:2 ~ 2:1.
3. a kind of preparation method of the sea-buckthorn beauty mud with lasting skin whitening, moisturizing effect according to claim 1, feature Be: the average grain diameter of step (2) the nanoscale jellyfish dry powder is 50 ~ 200nm.
4. a kind of preparation method of the sea-buckthorn beauty mud with lasting skin whitening, moisturizing effect according to claim 1, feature Be: step (2) incorporation time is 60 ~ 90min.
5. a kind of preparation method of the sea-buckthorn beauty mud with lasting skin whitening, moisturizing effect according to claim 1, feature Be: the parts by weight of step (2) each raw material are 20 ~ 30 parts by weight of jellyfish dry powder, 30 ~ 55 parts by weight of Hippophae Rhamnoides L. juice A, purple perilla 5 ~ 10 parts by weight of aldehyde, 20 ~ 30 parts by weight of ethyl alcohol.
6. a kind of preparation method of the sea-buckthorn beauty mud with lasting skin whitening, moisturizing effect according to claim 1, feature Be: the average grain diameter of step (3) the nanoscale Composite Shell powder is 100 ~ 300nm.
7. a kind of preparation method of the sea-buckthorn beauty mud with lasting skin whitening, moisturizing effect according to claim 1, feature Be: step (3) incorporation time is 30 ~ 60min.
8. a kind of preparation method of the sea-buckthorn beauty mud with lasting skin whitening, moisturizing effect according to claim 1, feature Be: the parts by weight of step (3) each raw material are, 12 ~ 18 parts by weight of shrimp shell, 12 ~ 18 parts by weight of crab shell, Hippophae Rhamnoides L. juice B 62 ~ 75 parts by weight, 1 ~ 2 parts by weight of hyaluronic acid.
9. a kind of preparation method of the sea-buckthorn beauty mud with lasting skin whitening, moisturizing effect according to claim 1, feature Be: the parts by weight of step (4) each raw material are 22 ~ 25 parts by weight of sea-buckthorn compound A, 15 ~ 18 weight of sea-buckthorn compound B Measure part, 3 ~ 5 parts by weight of ginkgo biloba p.e, 3 ~ 5 parts by weight of bamboo extractive, 2 ~ 4 parts by weight of bamboo charcoal powder, 1 ~ 2 weight of lecithin Part, 2 ~ 4 parts by weight of talcum powder, 1 ~ 2 parts by weight of glycerol, 2 ~ 3 parts by weight of seaweed glue, 1 ~ 2 parts by weight of hydroxyethyl cellulose, deionization 28 ~ 46 parts by weight of water.
10. a kind of sea-buckthorn with lasting skin whitening, moisturizing effect that any one of claim 1 ~ 9 preparation method is prepared Beauty mud.
CN201811458055.1A 2018-11-30 2018-11-30 A kind of sea-buckthorn beauty mud and preparation method with lasting skin whitening, moisturizing effect Withdrawn CN109464362A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109846812A (en) * 2019-04-18 2019-06-07 王志华 A kind of beauty treatment cosmetics and preparation method containing sea-buckthorn complex
CN110025539A (en) * 2019-05-24 2019-07-19 王志华 One kind is from osmotrophy type cosmetics and preparation method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109846812A (en) * 2019-04-18 2019-06-07 王志华 A kind of beauty treatment cosmetics and preparation method containing sea-buckthorn complex
CN110025539A (en) * 2019-05-24 2019-07-19 王志华 One kind is from osmotrophy type cosmetics and preparation method

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Application publication date: 20190315