CN109464345A - A kind of Tea Saponin lotion and preparation method thereof - Google Patents
A kind of Tea Saponin lotion and preparation method thereof Download PDFInfo
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- CN109464345A CN109464345A CN201910071806.2A CN201910071806A CN109464345A CN 109464345 A CN109464345 A CN 109464345A CN 201910071806 A CN201910071806 A CN 201910071806A CN 109464345 A CN109464345 A CN 109464345A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The present invention relates to natural plants lotion fields, in particular to a kind of Tea Saponin lotion and preparation method thereof.The raw material of this Tea Saponin lotion includes: 2-40 parts of Tea Saponin, 1-10 parts of camomile extract, 1-10 parts of Magnolia cortex P.E, 1-10 parts of angelica extract, 1-10 parts of alkyl glycosides and 20-94 parts of water.The preparation method of this Tea Saponin lotion includes: that camomile extract is added in Tea Saponin solution, and stirring is to being completely dissolved；Magnolia cortex P.E, angelica extract and alkyl glycosides is added, stirs to the step of being completely dissolved.The Tea Saponin lotion prepared in this way, it is good to have a foaming properties, and has pharmacological function, and sterilizing and itch-relieving effect is good, safety and environmental protection and the characteristics of easy preparation low in cost.
Description
Technical field
The present invention relates to natural plants lotion fields, in particular to a kind of Tea Saponin lotion and preparation method thereof.
Background technique
Currently, the pet lotion product brand to circulate in the market is various, class is irregular.Some low grade products are most
It is made of various synthetic surfactants and fungicide.Due to surfactant and fungicide irritation and toxicity compared with
Greatly, and biological degradability is poor.If chemically synthesized surfactant is used for a long time, the excessive degreasing of skin can be made, lead to nocuousness
Substance remains in skin, and then hair root of hair is caused to expand, and generates irritation itch, scurf, so as to cause depilation, hair quality damage
Wound.Fungicide is used for a long time, can develop drug resistance.In addition, surfactant is most important component in lotion, biodegrade
The safety of property and catabolite, is directly related to the ecological environment of lotion.Therefore the lotion of the prior art is unfavorable for animal
Health and environmental protection.
In view of this, the present invention is specifically proposed.
Summary of the invention
The purpose of the present invention is to provide a kind of Tea Saponin lotions, utilize the Natural surfactant of Tea Saponin, sweet with ocean
The extracts such as chrysanthemum, Cortex Magnoliae Officinalis, Radix Angelicae Sinensis and nonionic surfactant alkyl glycosides etc. are compounded, and prior art biology is overcome to drop
Guards escorting prisoners is also easy to produce the problems such as drug resistance.
It is simple process, low in cost another object of the present invention is to provide a kind of preparation method of Tea Saponin lotion,
It is suitble to large-scale production.It is good that the lotion being prepared in this way has foaming properties, and has pharmacological function, sterilization
The features such as antipruritic effect is good, safety and environmental protection.
Another object of the present invention is to provide a kind of lotions of pet sterilization, can alleviate pet skin itch, hair
Hair knots and reduces the functions such as scurf.
Above-mentioned purpose to realize the present invention, the following technical scheme is adopted:
A kind of Tea Saponin lotion provided by the invention, raw material include: according to parts by weight
2-40 parts of Tea Saponin, 1-10 parts of camomile extract, 1-10 parts of Magnolia cortex P.E, 1-10 parts of angelica extract, alkane
1-10 parts of base glucosides and 20-94 parts of water.
A kind of preparation method of Tea Saponin lotion provided by the invention comprising following steps:
Camomile extract, which will be added, to be stirred in Tea Saponin solution to being completely dissolved；
It is added Magnolia cortex P.E, angelica extract and alkyl glycosides, stirring is to being completely dissolved.
Compared with the existing technology, the invention has the following advantages:
Tea Saponin lotion provided by the invention, using the Natural surfactant of Tea Saponin, with chamomile, Cortex Magnoliae Officinalis, Radix Angelicae Sinensis etc.
Extract and nonionic surfactant alkyl glycosides etc. are compounded, overcome the prior art biodegrade it is poor, be also easy to produce it is resistance to
The problems such as pharmacological property, Tea Saponin have the function of good emulsification, dispersion, foaming, wet etc..It is by regenerating using alkyl glycosides
A kind of nonionic plant surface activating agent of the natural alcohol and glucose of resource, Starch synthesis, has nonionic and anionic surface concurrently
Active characteristic had not only had good green ecological safety activity, but also has had multifunction surface activity, and with nontoxic, harmless, right
Skin is non-stimulated and antibacterial activity.Have that foaming properties are good, sterilization by the Tea Saponin lotion of above-mentioned raw materials compounding preparation
Antipruritic effect is good, safety and environmental protection and the features such as easy preparation low in cost.
Specific embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the invention.It is not specified in embodiment specific
Condition person carries out according to conventional conditions or manufacturer's recommended conditions.Reagents or instruments used without specified manufacturer is
The conventional products that can be obtained by commercially available purchase.
A kind of Tea Saponin lotion that the embodiment of the present invention provides, raw material include: according to parts by weight
2-40 parts of Tea Saponin, 1-10 parts of camomile extract, 1-10 parts of Magnolia cortex P.E, 1-10 parts of angelica extract, alkane
1-10 parts of base glucosides, 20-94 parts of Ji Shuiwei.
Tea Saponin also known as saponin, saponin, Tea Saponin are a kind of glycoside compounds by extracting in tea oil tree seed.
The structure category triterpenoid saponin of Tea Saponin, is made of sugared body, aglucon and organic acid, and from molecular structure, one end of sugared body is parent
Water base group is connected by ehter bond with other end hydrophobic group, the glucoside member that hydrophobic grouping is connected in the form of ester bond and organic acid structure
At, thus be a kind of natural nonionic green surfactant, and there are hydrophilic and two kinds of active groups of oleophylic, it can be significant
The surface tension of solution is reduced, the surface tension of solution declines with the increase of Tea Saponin concentration, and surface-active is not by pH value
And water quality impact, the characteristics such as disinfection, sterilization, antisepsis can be played.With good emulsification, dispersion, wet, decontamination, foaming with
A variety of surface-actives such as foam stabilizing.Tea Saponin critical micelle concentration (CMC) is low, is 0.5% or so, Tea Saponin generates after shaking with water
Reticulated foams, foaming power is strong, is that foaming is normal within the scope of 4-10 and foam is stablized persistently in pH, also has surfactant
Specific micelle forma-tion phenomenon and very strong hard water resistance power, therefore bubble effect is not influenced by water hardness.
Further, Tea Saponin is not only good surfactant, and there are also stronger anti-inflammatory, impermeabilisation and analgesias etc.
The pharmacological action of aspect especially has good resistancing action to Bacteria skin infection.Specifically, Tea Saponin is to a variety of initiation skin diseases
Mycophyta and Escherichia coli have inhibiting effect, such as to the fungi of skin common causative such as Candida albicans, red mentagrophytes, purple
Color tinea bacterium, acrothesium floccosum and trichophyton gypseum etc. have apparent inhibiting effect, and have many characteristics, such as apparent anti-inflammatory,
It can make in the inflammation initial phase, capillary permeability normalization, belong to nontoxic, use is safe.In the embodiment of the present invention, preferably
Ground uses Tea Saponin content for the Tea Saponin raw material of 95%-100%.
Further include alkyl glycosides in the Tea Saponin lotion of the embodiment of the present invention, APG for short, be by regenerated resources natural alcohol and
A kind of nonionic plant surface activating agent of glucose, Starch synthesis, has the characteristic of nonionic and anion surface active concurrently, both
With good environment-friendly and green ecological safety activity, and there is multifunction surface activity, it is nontoxic, harmless, non-stimulated to skin, have
Broad spectrum antibiotic activity.Alkyl polyglycoside surface tension is low, clean effect is good；Compatibility is good, can be with various ionics, nonionic
Type surfactant compound, synergistic effect are obvious；Bubble is good, foaming abundancy is fine and smooth；Dissolubility is good, resistance to highly basic, resistance to strong acid, produces
Product thickening effect is significant；It is good with skin-friendliness, the mildness of formula can be significantly improved, it is nontoxic, harmless and biodegradable
Rapidly thoroughly.Secondly, also with no cloud point, HLB value is adjustable, wetting power is strong, be easy to dilute, without gelatin phenomenon, it is easy to use, resistance to
Hard water and salt-resistance by force can advantages.
Further, ratio of the CMC one-component wants low after alkyl glycosides is compounded with Tea Saponin, this illustrates to compound
Rear surface activity improves, and the micellar concentration that faces that alkyl glycosides is compounded with nonionic surfactant is more below alkyl glycosides and yin
The critical micelle concentration of ionic surface active agent compounding, and Tea Saponin is natural nonionic surfactant, therefore, alkyl sugar
Glycosides compounds rear surface activity with Tea Saponin more preferably.After alkyl glycosides and Tea Saponin compounding, emulsification times extend, and emulsifying ability increases
By force；After alkyl glycosides and Tea Saponin compounding, the performances such as wetting power and foam power all increase, and ratio when compounding
Also also there is certain relationship with correlated performance.
Camomile extract is the drying herb extract of compositae plant chamomile, mainly contains flavonoids, saponin(e, more
Sugar, volatile oil isoreactivity ingredient, tool anti-inflammatory inhibit fungi, spasmolysis and the effects of antiallergy, help improve eczema, pimples,
Bleb, chronic eczema, hypersensitization skin and general allergic phenomena.Camomile extract can be the capilary for calming down rupture, promote bullet
Property, it is splendid to the dry skin easily itched.Specifically, the blue sesame oil in camomile extract has bacteriostasis, chamomile is mentioned
Take the volatile oil in object that there is bactericidal effect；Camomile extract is able to suppress golden staphylococci, streptococcus and candida albicans etc.
Activity, camomile extract is primarily due in its extract containing flavonoid class substance the inhibiting effect of bacterium.
Magnolia cortex P.E, principle active component are phenols, volatile oil and alkaloid etc., are wherein played a major role in phenols
Have magnolol, honokiol and magnolia bark total-phenol；Containing there are two types of anti-inflammatory isomers substance in Magnolia cortex P.E, magnolol with
Honokiol has the pharmacological actions such as anti-inflammatory, antibacterial, anti-oxidant, antitumor, inhibition morphine withdrawal syndrome.Specifically, Cortex Magnoliae Officinalis
Phenol and honokiol can effectively clear intracorporal oxygen radical.By inhibit NF-β (transcription factor) activation, magnolol with and
Magnolol can generate a kind of anti-inflammatory effect of collaboration.In addition, they play the role of anti-oxidant, antibacterial and anti-angiogenesis, simultaneously
Reduce harmful substance.There are also very strong antiallergy effects for Magnolol and Honokiol.Cortex Magnoliae Officinalis has stronger antibacterial action, resists
Bacterium spectrum is wider, and antibacterial properties are stablized, and are not easy to be heated, the destruction of acid, alkali.To golden yellow plucked instrument staphylococcus, Escherichia coli, green pus bar
Bacterium etc. all has a strong inhibitory effect, and has inhibiting effect to Common Pathogenic dermatophyte.
Angelica extract oils containing volatility and organic acid etc., angelica extract can inhibit blood platelet AA metabolism and blood platelet
5-HI release, there is mild analgesic activity；Phenol oil in angelica extract has preferable bacteriostasis, to external dysentery,
Escherichia coli, corynebacterium diphtheriae, comma bacillus and α, β hemolytic streptococcus have antibacterial action；Angelica extract A3Position energy
Inhibit PGE2The expression of yield, cyclooxygenase-2 (COX-2) activity and COX-2mRNA and albumen, therefore angelica extract also has
There is antiinflammation, can be used for illnesss such as suppurative maxillary sinusitis, acute nephritis, chorionitis and psoriasis.
Further, camomile extract, Magnolia cortex P.E and angelica extract are preferably by solvent extraction legal system
It is standby to obtain, solvent effective component extracting from solid material is used, solvent used must have to dissolve each other with extracted solute
Characteristic.After vegetable material is crushed, be put into suitable container, be added several times amount solvent, can be used dipping, diacolation, decoction,
Reflux and continuous extraction extract.Specifically, it is dissolved each other according to the solid materials such as chamomile, Cortex Magnoliae Officinalis and Radix Angelicae Sinensis and water or alcohol
Characteristic selects solvent appropriate to extract.Preferably, camomile extract, Magnolia cortex P.E and angelica extract are all made of
The mode of water extract-alcohol precipitation is extracted, and water extraction and alcohol precipitation method (water alcohol method) is meant in above-mentioned raw materials water extracting liquid, and ethyl alcohol, which is added, to be made to reach
Different alcohol contents, some drugs ingredient solubility in alcoholic solution, which reduces, is precipitated precipitating, enables Aqueous extracts essence after separation of solid and liquid
The method of system.Solubility is preferable in water for the extract being prepared in this way, prepares Tea Saponin lotion mistake for the later period
Journey provides convenience.
Further, the specification of camomile extract, Magnolia cortex P.E and angelica extract is 20:1, i.e. 20 parts of oceans
The extraction of camomile raw material is concentrated into 1 part of camomile extract, and 20 parts of magnolia bark raw material extractions are concentrated into 1 part of Magnolia cortex P.E, and 20 parts are worked as
Raw material extraction is returned to be concentrated into 1 part of angelica extract.Angelica extract and Magnolia cortex P.E compatibility, which have, to act synergistically, the outer used time,
The antiphlogistic antibacterial that the effect of its antiphlogistic antibacterial is greater than when angelica extract is used alone or Magnolia cortex P.E is used alone acts on.
Embodiment of the present invention also provides a kind of preparation method of Tea Saponin lotion, comprising the following steps:
S1, Tea Saponin solution is prepared
2-40 parts of Tea Saponins are soluble in water, it is made it completely dissolved in 35-65 DEG C of at a temperature of stirring.The reason for this is that tea
Saponin is insoluble in cold water, is slightly dissolved in warm water, is soluble in hot water, therefore need to make it completely dissolved in 35-65 DEG C of at a temperature of stirring.
Obtain Tea Saponin solution.Further, in the present embodiment, water is preferably deionized water, and which removes be in ion shape in raw water
The impurity of formula influences the effect of lotion obtained by foreign ion.
S2, camomile extract is added
By in Tea Saponin solution obtained in 1-10 parts of camomile extracts addition S1 steps, in course of dissolution, temperature is kept
Degree is 35-65 DEG C, and is stirred continuously until that camomile extract is completely dissolved.
S3, Tea Saponin lotion is prepared
1-10 parts of Magnolia cortex P.E, 1-10 parts of angelica extract, 1-10 parts of alkyl glycosides are dissolved in obtained in S2 step
In solution, under the conditions of temperature is 20 DEG C -35 DEG C, stirred evenly with the speed of 50-100 turns/min.
Further, foam can be generated in Tea Saponin course of dissolution, is defoamed by way of standing naturally, followed by
0.45 μm or 0.22 μm of industrial filtering with microporous membrane, miillpore filter mainly by purification nitrocotton, be added proper amount of acetic acid cellulose,
Acetone, n-butanol, ethyl alcohol, etc. be made, it is hydrophilic, have non-toxic sanitary, be a kind of porous membrane filtration material, pore-size distribution
The micropore of relatively uniform penetrability, microporosity are up to 80 ‰ absolute hole diameter.For aseptic filtration, while filtering out and not being completely dissolved
Raw material and raw material in undissolved impurity, obtain Tea Saponin lotion.
Feature and performance of the invention are described in further detail with reference to embodiments.
Embodiment 1
A kind of Tea Saponin lotion provided in this embodiment, the raw material of lotion include: according to parts by weight
It Tea Saponin 10g, camomile extract 10g, Magnolia cortex P.E 10g, angelica extract 5g, alkyl glycosides 10g and goes
Ionized water 55g.
In the present embodiment Tea Saponin lotion the preparation method comprises the following steps:
S1, Tea Saponin lotion is prepared
55g deionized water will be added in reaction vessel, deionized water is heated to 35-65 DEG C, is preferably in the present embodiment
50 DEG C, then by 10g Tea Saponin be added deionized water in, and stir until Tea Saponin be completely dissolved, obtain Tea Saponin solution.
S2, camomile extract is added
Into Tea Saponin solution obtained in S1 step, 5g camomile extract is added, and keep the temperature at 35-65
DEG C, 42 DEG C are preferably kept in the present embodiment, stirring is until camomile extract is completely dissolved.
S3, Tea Saponin lotion is prepared
Magnolia cortex P.E 10g, angelica extract 5g, alkyl glycosides 10g are added in step (2) acquired solution, stirred
Fully dissolved is stirred evenly, the dissolution in the present embodiment under the conditions of temperature is 20 DEG C -35 DEG C with the speed of 50-100 turns/min
Condition is preferred are as follows: temperature is 25 DEG C, and speed of agitator is 80 turns/min.After above-mentioned raw materials are completely dissolved, stand naturally to eliminate thickness
The foam generated in plain extract, angelica extract and alkyl glycosides course of dissolution, after foam completely eliminates, the present embodiment
In, be preferably 0.45 μm of industrial membrane filtration with aperture, can effectively catching microorganism, obtain with anti-inflammation and sterilization and can
For cleaning the Tea Saponin lotion of pet.
Embodiment 2
A kind of Tea Saponin lotion provided in this embodiment, the raw material of lotion include: according to parts by weight
Tea Saponin 20g, camomile extract 1g, Magnolia cortex P.E 5g, angelica extract 5g, alkyl glycosides 6g and go from
Sub- water 63g.
The preparation method and the preparation method in embodiment 1 of Tea Saponin lotion in the present embodiment are almost the same.
Embodiment 3
A kind of Tea Saponin lotion provided in this embodiment, the raw material of lotion include: according to parts by weight
Tea Saponin 30g, camomile extract 5g, Magnolia cortex P.E 5g, angelica extract 1g, alkyl glycosides 4g and go from
Sub- water 55g.
The preparation method and the preparation method in embodiment 1 of Tea Saponin lotion in the present embodiment are almost the same.
Embodiment 4
A kind of Tea Saponin lotion provided in this embodiment, the raw material of lotion include: according to parts by weight
Tea Saponin 40g, camomile extract 5g, Magnolia cortex P.E 1g, angelica extract 2g, alkyl glycosides 2g and go from
Sub- water 50g.
The preparation method and the preparation method in embodiment 1 of Tea Saponin lotion in the present embodiment are almost the same.
Test example 1
By Tea Saponin lotion obtained in embodiment 1 carry out clinical test, randomly select 30 have hair seriously knot,
The pet dog of pruitus, scurf and trichoxerosis symptom is tested.Wherein male dogs 15, female dog 15, age
It is distributed in 1-5 years old, 30 pet dogs is divided into hair knotting group, pruitus group, scurf group and trichoxerosis according to symptom
Group in 30 pet dogs, has 12 with hair knotting symptom, has 10 with skin itching symptom, have scurf disease
Shape has 6, and has 14 with trichoxerosis symptom.Wherein there are 8 dog hair hair knottings and trichoxerosis, 4 dog skins
There are also scurfs simultaneously for itch.
Specifically, Tea Saponin lotion in the present embodiment 1 and in the market existing pet lotion are taken, it is respectively that it is dilute with water
5 times are released, lotion is smeared in affected part, does not have to clear water and rinse, have a bath again every other day primary, is used continuously 2 courses for the treatment of, each course for the treatment of 7 days,
Check that affected part locally has no adverse reaction.Test result is as shown in table 1:
The test result of 1 embodiment of table, 1 Tea Saponin lotion
| Hair knotting group | Pruitus group | Scurf group | Trichoxerosis group | |
| Experimental animal number (only) | 12 | 10 | 6 | 14 |
| Significant figure (only) | 12 | 8 | 5 | 13 |
| Efficient (%) | 100 | 80 | 83.3 | 92.9 |
Test example 2
Randomly select 30 seriously knots with hair, the pet dog progress of the symptoms such as pruitus, scurf, trichoxerosis
Animal experiment, wherein male 15, female 15, age distribution was in 1-5 years old.It include that there is hair knotting disease in 30 pet dogs
Shape has 12, has 9 with skin itching symptom, there is scurf symptom to have 7, and having with trichoxerosis symptom
13, wherein having, 6 dog hair hairs knot and trichoxerosis, 5 dog pruituses while also scurf take the embodiment of the present invention 2
Tea Saponin lotion its be diluted with water 5 times, other use consistent in step and test example 1.Test result is as follows:
The test result of 2 embodiment of table, 2 Tea Saponin lotion
| Hair knotting group | Pruitus group | Scurf group | Trichoxerosis group | |
| Experimental animal number (only) | 12 | 9 | 7 | 13 |
| Significant figure (only) | 12 | 8 | 6 | 13 |
| Efficient (%) | 100 | 88.9 | 85.7 | 100 |
Test example 3
Randomly select 30 seriously knots with hair, the pet dog progress of the symptoms such as pruitus, scurf, trichoxerosis
Animal experiment, wherein male 15, female 15, age distribution was in 1-5 years old.It include that there is hair knotting disease in 30 pet dogs
Shape has 13, has 10 with skin itching symptom, there is scurf symptom to have 8, and with trichoxerosis symptom
There are 13,8 dog hair hairs knot and trichoxerosis, 6 dog pruituses while also scurf take the embodiment of the present invention wherein having
It is diluted with water 5 times with 3 Tea Saponin lotion, other use consistent in step and test example 1.Test result is as follows:
The test result of 3 embodiment of table, 3 Tea Saponin lotion
| Hair knotting group | Pruitus group | Scurf group | Trichoxerosis group | |
| Experimental animal number (only) | 13 | 10 | 8 | 13 |
| Significant figure (only) | 13 | 9 | 8 | 13 |
| Efficient (%) | 100 | 90 | 100 | 100 |
Test example 4
Randomly select 30 seriously knots with hair, the pet dog progress of the symptoms such as pruitus, scurf, trichoxerosis
Animal experiment, wherein male 15, female 15, age distribution was in 1-5 years old.It include that there is hair knotting disease in 30 pet dogs
Shape has 11, has 10 with skin itching symptom, there is scurf symptom to have 9, and with trichoxerosis symptom
There are 13,9 dog hair hairs knot and trichoxerosis, 4 dog pruituses while also scurf take the embodiment of the present invention wherein having
It is diluted with water 5 times with 4 Tea Saponin lotion, other use consistent in step and test example 1.Test result is as follows:
The test result of 4 embodiment of table, 4 Tea Saponin lotion
| Hair knotting group | Pruitus group | Scurf group | Trichoxerosis group | |
| Experimental animal number (only) | 11 | 10 | 9 | 13 |
| Significant figure (only) | 11 | 9 | 8 | 13 |
| Efficient (%) | 100 | 90 | 88.89 | 100 |
By the data of table 1-4 it is found that Tea Saponin lotion of the invention is improving hair knotting, pruitus, scurf, hair
In terms of the symptoms such as dry, effective percentage is significantly better than existing product in the market.It can be seen that Tea Saponin lotion provided by the invention kills
Bacterium anti-inflammatory effects are good, and have good clean effect.
In conclusion a kind of Tea Saponin lotion provided in the embodiment of the present invention, uses the Natural surfactant of Tea Saponin,
It is compounded with extracts and nonionic surfactant alkyl glycosides etc. such as chamomile, Cortex Magnoliae Officinalis, Radix Angelicae Sinensis, overcomes the prior art
Biodegrade is poor, is also easy to produce the problems such as drug resistance, and Tea Saponin has the function of good emulsification, dispersion, foaming, wet etc..Using
Alkyl glycosides is had concurrently by a kind of nonionic plant surface activating agent of the natural alcohol and glucose of regenerated resources, Starch synthesis
The characteristic of nonionic and anion surface active had not only had good environment-friendly and green ecological safety activity, but also has had multifunction surface
Activity, and have it is nontoxic, harmless, non-stimulated to skin, have broad spectrum antibiotic activity.
Although illustrate and describing the present invention with specific embodiment, it will be appreciated that without departing substantially from of the invention
Many other change and modification can be made in the case where spirit and scope.It is, therefore, intended that in the following claims
Including belonging to all such changes and modifications in the scope of the invention.
Claims (10)
1. a kind of Tea Saponin lotion, which is characterized in that the raw material of the lotion includes: according to parts by weight
2-40 parts of Tea Saponin, 1-10 parts of camomile extract, 1-10 parts of Magnolia cortex P.E, 1-10 parts of angelica extract, alkyl sugar
1-10 parts of glycosides and 20-94 parts of water.
2. a kind of Tea Saponin lotion according to claim 1, which is characterized in that according to parts by weight, the Tea Saponin is
2-20 parts, the camomile extract be 1-5 parts, the Magnolia cortex P.E is 1-5 parts, the angelica extract is 1-4 parts, institute
Stating alkyl glycosides is 2-6 parts, 60-93 parts of Ji Shuiwei.
3. a kind of Tea Saponin lotion according to claim 2, which is characterized in that according to parts by weight, the Tea Saponin is
2-15 parts, the camomile extract be 1-3 parts, the Magnolia cortex P.E is 1-3 parts, the angelica extract is 1-4 parts, institute
State that alkyl glycosides is 2-6 parts and the water is 69-93 parts.
4. a kind of Tea Saponin lotion according to claim 1, which is characterized in that the specification of the Tea Saponin is: Tea Saponin
Content be 95%-100%.
5. a kind of Tea Saponin lotion according to claim 1, which is characterized in that the camomile extract, the Cortex Magnoliae Officinalis
The specification of extract and the angelica extract is 20:1, i.e. 20 parts of chamomile raw material extractions are concentrated into 1 part of chamomile and mention
Object is taken, 20 parts of magnolia bark raw material extractions are concentrated into 1 part of Magnolia cortex P.E, and 20 parts of Radix Angelicae Sinensis raw material extractions are concentrated into 1 part of angelica extract.
6. a kind of Tea Saponin lotion according to claim 5, which is characterized in that the camomile extract, the Cortex Magnoliae Officinalis
Extract and the angelica extract are prepared by solvent extraction method, it is preferable that use water extract-alcohol precipitation method.
7. a kind of preparation method of Tea Saponin lotion, which comprises the following steps:
Camomile extract, which will be added, to be stirred in Tea Saponin solution to being completely dissolved；
It is added Magnolia cortex P.E, angelica extract and alkyl glycosides, stirring is to being completely dissolved.
8. a kind of preparation method of Tea Saponin lotion according to claim 7, which is characterized in that the Tea Saponin and described
The dissolution conditions of camomile extract are: solution is heated to 35-65 DEG C.
9. a kind of preparation method of Tea Saponin lotion according to claim 7, which is characterized in that the Magnolia cortex P.E,
The angelica extract and the dissolution conditions of the alkyl glycosides are: under the conditions of 20 DEG C -35 DEG C, with 50-100 turns/min's
Speed stirs evenly.
10. a kind of lotion for pet sterilization, which is characterized in that it passes through according to claim 7-9 any one
A kind of preparation method of Tea Saponin lotion is prepared.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101879163A (en) * | 2010-02-08 | 2010-11-10 | 华南农业大学 | In vitro insecticidal shampoo for pet and preparation and application method thereof |
| CN102429844A (en) * | 2011-12-07 | 2012-05-02 | 广州青能健日用品有限公司 | Biological environment-friendly antioxidant itching-relieving bath wash and preparation method thereof |
| CN103637964A (en) * | 2013-12-20 | 2014-03-19 | 黄山市徽山生物科技有限公司 | Preparation method of shower gel |
| CN104523459A (en) * | 2014-12-16 | 2015-04-22 | 青岛海芬海洋生物科技有限公司 | Biological degerming component-containing shampoo special for pet dog and preparation method of biological degerming component-containing shampoo |
| CN107049868A (en) * | 2017-05-03 | 2017-08-18 | 中国农业科学院兰州畜牧与兽药研究所 | A kind of pet detergent with sterilizing and preparation method thereof |
-
2019
- 2019-01-25 CN CN201910071806.2A patent/CN109464345A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101879163A (en) * | 2010-02-08 | 2010-11-10 | 华南农业大学 | In vitro insecticidal shampoo for pet and preparation and application method thereof |
| CN102429844A (en) * | 2011-12-07 | 2012-05-02 | 广州青能健日用品有限公司 | Biological environment-friendly antioxidant itching-relieving bath wash and preparation method thereof |
| CN103637964A (en) * | 2013-12-20 | 2014-03-19 | 黄山市徽山生物科技有限公司 | Preparation method of shower gel |
| CN104523459A (en) * | 2014-12-16 | 2015-04-22 | 青岛海芬海洋生物科技有限公司 | Biological degerming component-containing shampoo special for pet dog and preparation method of biological degerming component-containing shampoo |
| CN107049868A (en) * | 2017-05-03 | 2017-08-18 | 中国农业科学院兰州畜牧与兽药研究所 | A kind of pet detergent with sterilizing and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 裘炳毅等: "《现代化妆品科学与技术（上册）》", 31 March 2016, 中国轻工业出版社 * |
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