CN104523459A - Biological degerming component-containing shampoo special for pet dog and preparation method of biological degerming component-containing shampoo - Google Patents
Biological degerming component-containing shampoo special for pet dog and preparation method of biological degerming component-containing shampoo Download PDFInfo
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- CN104523459A CN104523459A CN201410777266.7A CN201410777266A CN104523459A CN 104523459 A CN104523459 A CN 104523459A CN 201410777266 A CN201410777266 A CN 201410777266A CN 104523459 A CN104523459 A CN 104523459A
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Abstract
The invention discloses a biological degerming component-containing shampoo special for a pet dog. The biological degerming component-containing shampoo comprises the following components in percentage by weight: 6.0-8.0% of a marine biological degerming agent, 7.0-9.0% of alkyl glycoside, 9.0-11.0% of cocofatty acylamido propyl betaines, 10.0-14.0% of cocoanut fatty acid diethanolamide, 1.0-1.5% of alkyl dimethyl polysiloxane, 2.0-2.5% of ivermectin, 1.0-1.5% of sodium chloride, 1.0-1.5% of citric acid, 0.5-1.0% of disodium ethylene diamine tetraacetate, 0-5.0% of essence and the balance of water. The biological degerming component-containing shampoo special for the pet dog can be used for effectively sterilizing and relieving itching as well as expelling parasite and preventing mites, and has no irritation on the skin of the pet dog.
Description
Technical field
the present invention relates to shampoo for pets, particularly relate to a kind of special shampoo of pet dog containing marine biological sterilization composition and preparation method thereof.
Background technology
along with the continuous increase of family's pet feeding, people are more and more concerned about the sanitary condition of house pet, virus, antibacterial and parasite that house pet is carried drastically influence the healthy of house pet and the mankind, select suitable shampoo for pets to be the effective way effectively stopping pathophoresis.
the skin of Canis familiaris L. becomes alkalescence, and skin layer is thin, only has 3-5 layer, very fragile.Shampoo as selected is not suitable for, and can make the skin pruritus of pet dog, allergy, occur the situations such as scurf, causes dermatosis.
at present, existing shampoo for pets kind is a lot, the main adding ingredient of shampoo for pets with sterilization antibacterial functions is: pyridine copper sulfate or other antifungal drugs (having ketoconazole, climbazole, selenium sulfide etc.), antimycotic medicine life-time service can produce drug resistance, and production cost is high.
Summary of the invention
an object of the present invention is to provide a kind of special shampoo of pet dog containing marine biological sterilization composition with sterilization and function for expelling pests.
another object of the present invention is to provide a kind of preparation method with the special shampoo of pet dog containing marine biological sterilization composition of sterilization and function for expelling pests.
the special shampoo of pet dog containing biological degerming composition of the present invention, percentage proportioning is as follows:
marine biological sterilization agent 4.0-8.0%;
alkyl polyglucoside 5.0-10.0%;
cocamido propyl betaine 8.0-12.0%;
cocoanut fatty acid diethanolamide 7.0-15.0%;
alkyl-dimethyl based polysiloxane 0.5-2.0%;
ivermectin 1.5-3.0%;
sodium chloride 1.0-1.5%;
citric acid 1.0-1.5%;
disodiumedetate 0.5-1.0%;
essence 0-5.0%;
surplus is water.
the preparation side of the special shampoo of pet dog containing biological degerming composition of the present invention
method, comprises the following steps:
step S10: the alkyl polyglucoside, cocamido propyl betaine, the cocoanut fatty acid diethanolamide that add proportional quantity in the water of 40-50 DEG C, carries out emulsifying and obtains mixed liquor A under stirring condition;
step S20: the alkyl-dimethyl based polysiloxane adding proportional quantity in mixed liquor A, is uniformly mixed to obtain mixed liquid B under 30-40 DEG C of temperature conditions;
step S30: add ivermectin, marine biological sterilization agent in mixed liquid B, after mix homogeneously, obtain mixed solution C;
step S40: add the disodiumedetate of proportional quantity, citric acid, sodium chloride and essence in mixed liquor C, mix homogeneously obtains the described special shampoo of pet dog containing biological degerming composition.
the special shampoo of pet dog containing biological degerming composition of the present invention, owing to containing sea
ocean biological disinfectant composition, therefore, after using, can be effectively degerming, and then there is antipruritic effect.Due to containing ivermectin, therefore there is effect that acarid is killed in anthelmintic.And because this each component containing the special shampoo of pet dog of biological degerming composition is nontoxic, non-stimulated, the free from corrosion material of the skin of pet dog, therefore this shampoo also has pet hair and non-stimulated, the free from corrosion advantage of skin.
the preparation method of the special shampoo of pet dog containing biological degerming composition of the present invention, due to the order by merging of each material and mixing condition comparatively reasonable, make each component mix homogeneously of the special shampoo of pet dog containing biological degerming composition obtained by preparation method of the present invention, good stability.
Detailed description of the invention
embodiment 1
the special shampoo of pet dog containing biological degerming composition of the present embodiment, percentage proportioning is as follows:
marine biological sterilization agent 4.0-8.0%;
alkyl polyglucoside 5.0-10.0%;
cocamido propyl betaine 8.0-12.0%;
cocoanut fatty acid diethanolamide 7.0-15.0%;
alkyl-dimethyl based polysiloxane 0.5-2.0%;
ivermectin 1.5-3.0%;
sodium chloride 1.0-1.5%;
citric acid 1.0-1.5%;
disodiumedetate 0.5-1.0%;
essence 0-5.0%;
surplus is water.
the special shampoo of pet dog containing biological degerming composition of the present embodiment, owing to containing
marine biological sterilization agent composition, therefore, after using, can be effectively degerming, and then there is antipruritic effect.Due to containing ivermectin, therefore there is effect that acarid is killed in anthelmintic.And because this each component containing the special shampoo of pet dog of biological degerming composition is nontoxic, non-stimulated, the free from corrosion material of the skin of pet dog, therefore this shampoo also has pet hair and non-stimulated, the free from corrosion advantage of skin.
in the present embodiment, in order to obtain better bactericidal and bacteriostatic effect and anthelminthic effect, the described special shampoo of pet dog containing biological degerming composition, percentage proportioning is as follows:
marine biological sterilization agent 6.0-8.0%;
alkyl polyglucoside 7.0-9.0%;
cocamido propyl betaine 9.0-11.0%;
cocoanut fatty acid diethanolamide 10.0-14.0%;
alkyl-dimethyl based polysiloxane 1.0-1.5%;
ivermectin 2.0-2.5.0%;
sodium chloride 1.0-1.5%;
citric acid 1.0-1.5%;
disodiumedetate 0.5-1.0%;
essence 0-5.0%;
surplus is water.
in the present embodiment, in order to obtain better antipruritic and antidandruff efficacy, preferably, described marine biological sterilization agent percentage proportioning is as follows:
carboxymethyl chitosan 1.0 ~ 2.0%;
sargassum polysaccharides 2.0 ~ 4.0%;
cecropin 6.0 ~ 8.0%;
n-acetylmuramide lycanohydrlase 1.5 ~ 3.5%;
water.82.5~89.5％。
in the present embodiment, preferably, described essence is plant essence.
in the present embodiment, in order to make the mixed effect of each component better, described hydromining pure water.
described cecropin can adopt notification number for the cecropin described in CN101104637B, can certainly adopt other cecropin.
described marine biological sterilization agent can be prepared as follows:
step S10: the carboxymethyl chitosan and the Sargassum polysaccharides that add proportional quantity in the water of 30 ~ 35 DEG C, carries out being uniformly mixed 10 ~ 20 minutes and obtains mixed liquor A;
step S20: the cecropin adding proportional quantity in mixed liquor A, the time be uniformly mixed is obtain mixed liquid B in 3 ~ 7 minutes;
step S30: the N-acetylmuramide lycanohydrlase adding proportional quantity in mixed liquid B, is uniformly mixed 3 ~ 7 minutes and obtains described degerming marine biological sterilization agent.
embodiment 2
present embodiments provide a kind of preparation method for the special shampoo of pet dog containing biological degerming composition described in embodiment 1, comprise the following steps:
comprise the following steps:
step S10: the alkyl polyglucoside, cocamido propyl betaine, the cocoanut fatty acid diethanolamide that add proportional quantity in the water of 40-50 DEG C, carries out emulsifying and obtains mixed liquor A under stirring condition;
step S20: the alkyl-dimethyl based polysiloxane adding proportional quantity in mixed liquor A, is uniformly mixed to obtain mixed liquid B under 30-40 DEG C of temperature conditions;
step S30: add ivermectin, marine biological sterilization agent in mixed liquid B, after mix homogeneously, obtain mixed solution C;
step S40: add the disodiumedetate of proportional quantity, citric acid, sodium chloride and essence in mixed liquor C, mix homogeneously obtains the described special shampoo of pet dog containing biological degerming composition.
the preparation method of the present embodiment due to the order by merging of each material and mixing condition comparatively reasonable, make each component mix homogeneously of the special shampoo of pet dog containing biological degerming composition obtained by preparation method of the present invention, good stability.
in the present embodiment, in order to make each component obtain better mixed effect, in described step S10, the temperature of described water is 45 DEG C, and carrying out emulsification times under stirring condition is 20-35 minute.
in the present embodiment, in order to make each component obtain better mixed effect, in described step S20, the time be uniformly mixed is 10-15 minute.
in the present embodiment, in order to make each component obtain better mixed effect, in described step S30, the time be uniformly mixed is 7-12 minute.
in the present embodiment, in order to make each component obtain better mixed effect, in described step S30
in the present embodiment, in order to make each component obtain better mixed effect, in described step S40, the time of being uniformly mixed is 10-15 minute.
in order to obtain portable shampoo, after the step s 40, also comprise step S50: after special for the pet dog containing biological degerming composition shampoo cooling, carry out subpackage.
embodiment 3
the present embodiment provides a kind of special shampoo of pet dog containing biological degerming composition, and percentage proportioning is as follows:
marine biological sterilization agent 8.0%;
alkyl polyglucoside 10.0%;
cocamido propyl betaine 12.0%;
cocoanut fatty acid diethanolamide 15.0%;
alkyl-dimethyl based polysiloxane 2.0%;
ivermectin 3.0%;
sodium chloride 1.0%;
citric acid 1.5%;
disodiumedetate 1.0%;
essence 0-5.0%;
surplus is water.
marine biological sterilization agent percentage proportioning in the present embodiment is: carboxymethyl chitosan 1.0%; Sargassum polysaccharides 2.0%; Cecropin 6.0%; N-acetylmuramide lycanohydrlase 1.5%; Water 89.5%.
the preparation method of the special shampoo of pet dog containing biological degerming composition of the present embodiment is carried out as follows:
step S301: add the alkyl polyglucoside of proportional quantity, cocamido propyl betaine, cocoanut fatty acid diethanolamide, alkyl-dimethyl based polysiloxane in the water of 35 DEG C, carries out emulsifying and obtains mixed liquor A in 15 minutes under stirring condition;
step S302: the marine biological sterilization agent adding proportional quantity in mixed liquor A, is uniformly mixed 3 minutes and obtains mixed liquid B under 25 DEG C of temperature conditions;
step S303: add the sodium citrate of proportional quantity, sodium chloride and essence in mixed liquid B, mixes 7 minutes to obtain the described special shampoo of pet dog containing biological degerming composition.
through experiment, the special shampoo of pet dog containing biological degerming composition of the present embodiment can effective sterilizing and itch-relieving, the anti-demodicid mite of anthelmintic, and after use, non-stimulated to pet dog skin.
embodiment 4
the present embodiment provides a kind of special shampoo of pet dog containing biological degerming composition, and percentage proportioning is as follows:
marine biological sterilization agent 2.0%;
alkyl polyglucoside 8.0%;
cocamido propyl betaine 7.0%;
cocoanut fatty acid diethanolamide 6.0%;
alkyl-dimethyl based polysiloxane 0.5%;
sodium chloride 1.0%;
sodium citrate 1.0%;
surplus is water.
marine biological sterilization agent percentage proportioning in the present embodiment is: carboxymethyl chitosan 2.0%; Sargassum polysaccharides 4.0%; Cecropin 8.0%; N-acetylmuramide lycanohydrlase 3.5%; Water 82.5%.
the preparation method of the special shampoo of pet dog containing biological degerming composition of the present embodiment is carried out as follows:
step S401: add the alkyl polyglucoside of proportional quantity, cocamido propyl betaine, cocoanut fatty acid diethanolamide, alkyl-dimethyl based polysiloxane in the water of 35 DEG C, carries out emulsifying and obtains mixed liquor A in 25 minutes under stirring condition;
step S402: the marine biological sterilization agent adding proportional quantity in mixed liquor A, is uniformly mixed 7 minutes and obtains mixed liquid B under 25 DEG C of temperature conditions;
step S403: add the sodium citrate of proportional quantity, sodium chloride and essence in mixed liquid B, mixes 12 minutes to obtain the described special shampoo of pet dog containing biological degerming composition.
step S404: after special for the pet dog containing biological degerming composition shampoo cooling, carry out subpackage.
through experiment, the special shampoo of pet dog containing biological degerming composition of the present embodiment can be effectively antipruritic, anti-dandruff, and after using, non-stimulated to head, corrosion-free, hair is submissiveer.
embodiment 5
the present embodiment provides a kind of special shampoo of pet dog containing biological degerming composition, and percentage proportioning is as follows:
marine biological sterilization agent 6.0%;
alkyl polyglucoside 7.5.0%;
cocamido propyl betaine 10.0%;
cocoanut fatty acid diethanolamide 11.0%;
alkyl-dimethyl based polysiloxane 1.5.0%;
ivermectin 2.50%;
sodium chloride 1.0 %;
citric acid 1.25%;
disodiumedetate 0.7%;
essence 0-5.0%;
surplus is water.
marine biological sterilization agent percentage proportioning in the present embodiment is: carboxymethyl chitosan 1.5%; Sargassum polysaccharides 3.0%; Cecropin 7.0%; N-acetylmuramide lycanohydrlase 2.0%; Water 86.5%.
through experiment, the special shampoo of pet dog containing biological degerming composition of the present embodiment can effectively sterilize antibacterial, and anti-demodicid mite anthelmintic, hair is smooth, to pet dog no skin irritation.
embodiment 6
the present embodiment provides a kind of special shampoo of pet dog containing biological degerming composition, and percentage proportioning is as follows:
marine biological sterilization agent 4.0 %;
alkyl polyglucoside 5.0 %;
cocamido propyl betaine 8.0 %;
cocoanut fatty acid diethanolamide 7.0 %;
alkyl-dimethyl based polysiloxane 0.5 %;
ivermectin 1.5 %;
sodium chloride 1.0 %;
citric acid 1.0 %;
disodiumedetate 0.5 %;
essence 0-5.0%;
surplus is water.
marine biological sterilization agent percentage proportioning in the present embodiment is: carboxymethyl chitosan 1.5%; Sargassum polysaccharides 3.0%; Cecropin 7.0%; N-acetylmuramide lycanohydrlase 2.0%; Water 86.5%.
through experiment, the special shampoo of pet dog containing biological degerming composition of the present embodiment can effectively sterilize antibacterial, and anti-demodicid mite anthelmintic, hair is smooth, to pet dog no skin irritation.
pharmacodynamics research of the present invention:
2.2 bacteriostasis
test strain: fungus, Candida albicans, staphylococcus aureus, Escherichia coli.
method: each test strain normal saline is made bacteria suspension, and to be diluted to turbidity be more than 2.0McF bacteria suspension, use normal saline dilution 100 times again, RPMII640 dilutes 10 times, test group (shampoo in the embodiment of the present invention 5) and matched group (health king washing liquid) doubling dilution, cultivate 72-96h in 96 well culture plates, slightly shake, 490nm place carries out photoelectric colorimetry.
table 1
2.3 conclusion
see table 1, the present invention has the inhibitory action (P < 0.05 or P < 0.01) of highly significant to the guinea pig skin pruritus test caused by histamine phosphate; Have a look at out through external susceptibility MIC test: the present invention all has stronger antibacterial action to fungus, Candida albicans, staphylococcus aureus, Escherichia coli.
more than test shows: the present invention has the effect of antipruritic antibacterial, therefore, above each microbial dandruff is also had to the effect of removal.
major Clinical research of the present invention:
the shampoo got in the embodiment of the present invention 3, embodiment 4, embodiment 5, embodiment 6 is tested, occupation mode be every two days once, duration is 16 days, the results are shown in Table 2, the visible special shampoo of pet dog containing biological degerming composition of the present invention has effect that is antipruritic, anti-dandruff, and non-stimulated to scalp, corrosion-free, use rear hair submissive.
table 2
Claims (7)
1. the special shampoo of pet dog containing biological degerming composition of the present invention, percentage proportioning is as follows:
Marine biological sterilization agent 6.0 ~ 8.0%;
Alkyl polyglucoside 7.0 ~ 9.0%;
Cocamido propyl betaine 9.0 ~ 11.0%;
Cocoanut fatty acid diethanolamide 10.0 ~ 14.0%;
Alkyl-dimethyl based polysiloxane 1.0 ~ 1.5%;
Ivermectin 2.0 ~ 2.5%;
Sodium chloride 1.0 ~ 1.5%;
Citric acid 1.0 ~ 1.5%;
Disodiumedetate 0.5 ~ 1.0%;
Essence 0.5 ~ 1.0%;
Surplus is water.
2. the special shampoo of pet dog containing biological degerming composition of the present invention, in order to obtain better antipruritic and antidandruff efficacy, preferably, described marine biological sterilization agent percentage proportioning is as follows:
Carboxymethyl chitosan 1.0 ~ 2.0%;
Sargassum polysaccharides 2.0 ~ 4.0%;
Cecropin 6.0 ~ 8.0%;
N-acetylmuramide lycanohydrlase 1.5 ~ 3.5%;
Water 82.5 ~ 89.5%.
3. the special shampoo of pet dog containing biological degerming composition of the present invention, preferably, described essence is plant essence.
4. the special shampoo of pet dog containing biological degerming composition of the present invention, in order to make the mixed effect of each component better, described hydromining pure water.
5. the cecropin described in can adopt notification number for the cecropin described in CN101104637B, can certainly adopt other cecropin.
6. the marine biological sterilization agent described in can be prepared as follows:
Step S10: the carboxymethyl chitosan and the Sargassum polysaccharides that add proportional quantity in the water of 30 ~ 35 DEG C, carries out being uniformly mixed 10 ~ 20 minutes and obtains mixed liquor A;
Step S20: the cecropin adding proportional quantity in mixed liquor A, the time be uniformly mixed is obtain mixed liquid B in 3 ~ 7 minutes;
Step S30: the N-acetylmuramide lycanohydrlase adding proportional quantity in mixed liquid B, is uniformly mixed 3 ~ 7 minutes and obtains described degerming marine biological sterilization agent.
7. the preparation side of the special shampoo of pet dog containing biological degerming composition of the present invention
Method, comprises the following steps:
Step S10: the alkyl polyglucoside, cocamido propyl betaine, the cocoanut fatty acid diethanolamide that add proportional quantity in the water of 40-50 DEG C, carries out emulsifying and obtains mixed liquor A under stirring condition;
Step S20: the alkyl-dimethyl based polysiloxane adding proportional quantity in mixed liquor A, is uniformly mixed to obtain mixed liquid B under 30-40 DEG C of temperature conditions;
Step S30: add ivermectin, marine biological sterilization agent in mixed liquid B, after mix homogeneously, obtain mixed solution C;
Step S40: add the disodiumedetate of proportional quantity, citric acid, sodium chloride and essence in mixed liquor C, mix homogeneously obtains the described special shampoo of pet dog containing biological degerming composition.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105476899A (en) * | 2015-12-08 | 2016-04-13 | 芜湖悠派护理用品科技股份有限公司 | Skincare cleaning solution for pets and preparation method of skincare cleaning solution |
| CN106726657A (en) * | 2016-12-26 | 2017-05-31 | 成都海麓生物科技有限公司 | Deep layer cleaning dipping shampoo and preparation method thereof |
| CN107049868A (en) * | 2017-05-03 | 2017-08-18 | 中国农业科学院兰州畜牧与兽药研究所 | A kind of pet detergent with sterilizing and preparation method thereof |
| CN109464345A (en) * | 2019-01-25 | 2019-03-15 | 湖北中博绿亚生物技术有限公司 | A kind of Tea Saponin lotion and preparation method thereof |
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2014
- 2014-12-16 CN CN201410777266.7A patent/CN104523459A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105476899A (en) * | 2015-12-08 | 2016-04-13 | 芜湖悠派护理用品科技股份有限公司 | Skincare cleaning solution for pets and preparation method of skincare cleaning solution |
| CN106726657A (en) * | 2016-12-26 | 2017-05-31 | 成都海麓生物科技有限公司 | Deep layer cleaning dipping shampoo and preparation method thereof |
| CN107049868A (en) * | 2017-05-03 | 2017-08-18 | 中国农业科学院兰州畜牧与兽药研究所 | A kind of pet detergent with sterilizing and preparation method thereof |
| CN107049868B (en) * | 2017-05-03 | 2020-06-05 | 中国农业科学院兰州畜牧与兽药研究所 | Disinfecting detergent for pets and preparation method thereof |
| CN109464345A (en) * | 2019-01-25 | 2019-03-15 | 湖北中博绿亚生物技术有限公司 | A kind of Tea Saponin lotion and preparation method thereof |
| CN112263499A (en) * | 2020-11-27 | 2021-01-26 | 佛山市南海东方澳龙制药有限公司 | Animal shampoo with antibacterial function and preparation method thereof |
| JP6945208B1 (en) * | 2020-11-27 | 2021-10-06 | 佛山市南海東方澳龍製薬有限公司Ｅａｓｔｅｒｎ Ａｌｏｎｇ Ｐｈａｒｍａｃｅｕｔｉｃａｌ ＣＯ．， ＬＴＤ． | Animal shampoo with antibacterial function and its manufacturing method |
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Application publication date: 20150422 |