CN109463759A - A kind of extraction of Herba Cistanches effective component and the production method of product - Google Patents
A kind of extraction of Herba Cistanches effective component and the production method of product Download PDFInfo
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- CN109463759A CN109463759A CN201811562675.XA CN201811562675A CN109463759A CN 109463759 A CN109463759 A CN 109463759A CN 201811562675 A CN201811562675 A CN 201811562675A CN 109463759 A CN109463759 A CN 109463759A
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- China
- Prior art keywords
- herba cistanches
- juice
- squeezing
- slag
- slags
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- QXMNTPFFZFYQAI-IMDKZJJXSA-N beta-sitosterol 3-O-beta-D-glucopyranoside Natural products CC[C@H](CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)O[C@@H]5C[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(C)C QXMNTPFFZFYQAI-IMDKZJJXSA-N 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 description 1
- 235000004883 caffeic acid Nutrition 0.000 description 1
- 229940074360 caffeic acid Drugs 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- QAIPRVGONGVQAS-UHFFFAOYSA-N cis-caffeic acid Natural products OC(=O)C=CC1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-UHFFFAOYSA-N 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- NPJICTMALKLTFW-OFUAXYCQSA-N daucosterol Chemical compound O([C@@H]1CC2=CC[C@H]3[C@@H]4CC[C@@H]([C@]4(CC[C@@H]3[C@@]2(C)CC1)C)[C@H](C)CC[C@@H](CC)C(C)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O NPJICTMALKLTFW-OFUAXYCQSA-N 0.000 description 1
- QDFKFNAHVGPRBL-UHFFFAOYSA-N daucosterol Natural products CCC(CCC(C)C1CCC2C1CCC3C2(C)CC=C4CC(CCC34C)OC5OC(CO)C(O)C(O)C5O)C(C)C QDFKFNAHVGPRBL-UHFFFAOYSA-N 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 229960000935 dehydrated alcohol Drugs 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 235000014134 echinacea Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000003311 flocculating effect Effects 0.000 description 1
- 238000005189 flocculation Methods 0.000 description 1
- 230000016615 flocculation Effects 0.000 description 1
- FBPFZTCFMRRESA-GUCUJZIJSA-N galactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-GUCUJZIJSA-N 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000008131 glucosides Chemical class 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 229930003658 monoterpene Natural products 0.000 description 1
- 235000002577 monoterpenes Nutrition 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229930182487 phenolic glycoside Natural products 0.000 description 1
- 150000007950 phenolic glycosides Chemical class 0.000 description 1
- CTYRPMDGLDAWRQ-UHFFFAOYSA-N phenyl hydrogen sulfate Chemical compound OS(=O)(=O)OC1=CC=CC=C1 CTYRPMDGLDAWRQ-UHFFFAOYSA-N 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 1
- 229950005143 sitosterol Drugs 0.000 description 1
- NLQLSVXGSXCXFE-UHFFFAOYSA-N sitosterol Natural products CC=C(/CCC(C)C1CC2C3=CCC4C(C)C(O)CCC4(C)C3CCC2(C)C1)C(C)C NLQLSVXGSXCXFE-UHFFFAOYSA-N 0.000 description 1
- 235000015500 sitosterol Nutrition 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 150000003648 triterpenes Chemical class 0.000 description 1
- 238000002525 ultrasonication Methods 0.000 description 1
- 238000002137 ultrasound extraction Methods 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
- A23L2/382—Other non-alcoholic beverages fermented
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/40—Effervescence-generating compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12J—VINEGAR; PREPARATION OR PURIFICATION THEREOF
- C12J1/00—Vinegar; Preparation or purification thereof
- C12J1/04—Vinegar; Preparation or purification thereof from alcohol
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
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Abstract
The invention discloses a kind of extraction of Herba Cistanches effective component and the production method of product, the fresh herba cistanches of excavation or drying Herba Cistanches rehydration are cleaned, broken, squeeze, filter, being concentrated, purifying and to obtain Herba Cistanches effective component sterling；Herba Cistanches product is made with the Herba Cistanches juice that squeezing obtains, Herba Cistanches product includes Herba Cistanches juice, Herba Cistanches inspissated juice, Herba Cistanches drink, desertliving cistanche wine, Herba Cistanches fine powder and product, Herba Cistanches probiotics fermention product.Herba Cistanches crushing juice rate of the present invention is high, improves active constituent content in Herba Cistanches juice, improves the production efficiency of Herba Cistanches juice, reduces production cost.
Description
Technical field
The invention belongs to traditional Chinese medicine ingredients to extract field, concretely relate to the extraction and system of a kind of Herba Cistanches effective component
The production method of product.
Background technique
Herba Cistanches Cistanche Herba also known as golden bamboo shoot, Goblin, desert cistanche, big rue, are orobanchaceae plant cistanche
The dry zone scale leaf of Cistanche deserticolaY.C.Ma or Cistanche tubulosa C.tubulosa (Schrenk) Wight
Fleshy stem, main product is in the Inner Mongol, Gansu, Xinjiang, Qinghai and other places；Warm-natured, sweet-salty is the key medicine of tonifying kidney and strengthening yang, relax bowel and defecation,
There is the good reputation of " desert ginseng ".The Herba Cistanches chemical component of current separated identification mainly have benzyl carbinol glycoside, iridoid and
Its glycoside, lignanoids and its glycoside, amino acid, oligosaccharide, polysaccharide, cupreol, daucosterol, succinic acid, tridecanol,
The chemical combination such as the bright colored glycosides of caffeic acid glycolipid, glycine betaine, awns, allantoin, galactitol, triterpene, phenolic glycoside, monoterpene glycosides, alkaloid, flavones
Object.Also microelements such as Mn, Fe, Zn, Sr and Ca rich in Herba Cistanches.Modern pharmacological research also turns out Herba Cistanches except tool
There is tonifying kidney and strengthening yang, outside functions of loosening bowel relieving constipation, also there is antifatigue, anti-aging, enhancing immunity of organisms and enhancing memory etc. to make
With.
Herba Cistanches extraction process of effective component has the following prior art.
According to " progress of Herba Cistanches " record of the 6th phase of volume 36 " drug evaluation research " in December, 2013: making red of heap of stone
Phenylethanoid glycoside in Cistanche tubulosa is extracted Deng using ethanol immersion, microwave method and supercritical ultrasonics technology, with preferred
Its optimum extracting method.Microwave loss mechanisms have efficient, time saving, simple operation and other advantages as the result is shown, can be used as pipe flower meat desert
Rong's benzyl carbinol glycoside extracting method.Zhang Kai carries out phenylethanoid glycoside in the Herba Cistanches fleshy stem of desert using soxhlet extraction
It extracts, and optimum extraction process is determined by orthogonal test, influence the principal element of phenylethanoid glycoside yield as the result is shown
It is to be asked when extracting, optimum extraction process is that 20 times of 95% alcohol refluxs of volume are added to extract 1h.Yang Jianhong etc. uses alcohol reflux
Ergot acteoside in Herba Cistanches is extracted, and optimizing optimum extraction process by orthogonal design is that 10 times of 60% alcohol refluxs of amount mention
Take 2h.Sheng Wei etc. extracts wheat-based diet using water extraction and alcohol precipitation method, then through H20: using dehydrated alcohol, ether after acid condition decoloration
Washing, is dried under reduced pressure purification wheat-based diet.Wu Bo etc. extracts glycine betaine in Herba Cistanches to seep the method that is equal to, and with alcohol medicinal extract yield and
Beet alkali content is index, by the preferred optimal extract process of orthogonal test, result be using 6 times of 75% ethyl alcohol of amount, with
The infiltration of 1mL/min is equal to VELOCITY EXTRACTION.
Ou Yangjie etc. has studied phenylethanoid glycoside in Herba Cistanches, glycine betaine and wheat-based diet while extracting integrated
Method is first extracted with the ultrasonication of first alcohol and water, then set through macroporous absorbent resin AB-8 column and strong-acid type sun from exchange
001 × 7 column of rouge and Sephadex G-75 gel column chromatography, respectively obtain benzyl carbinol glycoside compound, glycine betaine and Herba Cistanches
Polysaccharide.Native heroic bearing etc. is general using Echinacea purpurea in Herba Cistanches, mono- sitosterol of β, total reducing sugar and dry extract yield is indexs, to ultrasonic extraction
Method, flocculation water extraction and alcohol extracting method carry out preferably, and it is more excellent with water extraction extraction of flocculating to prompt Herba Cistanches.Sun Ping etc. is mentioned using microwave
Technology is taken to extract general flavone and polysaccharide in Herba Cistanches with high concentration ethanol, the method makes to ask shortening when reaction, and extraction efficiency improves,
It has potential application.
The effective component of Herba Cistanches is mainly benzyl carbinol glycoside, which has antibacterial, anti-inflammatory, liver protection, antiviral, anti-
A variety of pharmacological activity such as oxidation, immunological regulation, enhancing memory, heart tonifying.Benzyl carbinol glycoside compound is showed relatively strong and wide
General pharmacological activity, and its characteristic of low toxicity, safety make it have potential developmental research value.
According to " the Chinese herbal medicine " " ratio of fresh goods Herba Cistanches slag and juice effective component that in December, 2008, the 12nd periodical of volume 39 was stepped on
Compared with " record, fresh goods herba cistanches directly crush pressure juice and obtain Herba Cistanches slag and juice, using Phenol-sulphate acid method measurement wheat-based diet
Amount；Using the macroreticular resin determined by ultraviolet spectrophotometry amount of benzyl carbinol glycosides；Using the lower HPLC of " Chinese Pharmacopoeia " Herba Cistanches
Method determines the amount of echinacoside and acteoside, as a result with wheat-based diet, phenylethanoid glycosides, echinacoside and hair
The amount of stamen flower glucosides principle active component is comprehensive evaluation index, and experiment shows in addition to polysaccharide, fresh goods Herba Cistanches slag part benzene second
The amount of the total glycosides of alcohol, echinacoside and acteoside is above juice, and the amount of polysaccharide does not have obvious gap.Wherein principle active component
785 times are differed with highest in juice in echinacoside slag, in addition, acteoside highest differs 230 times, phenylethanoid glycosides highest phase
Poor 7 times；Experiments have shown that fresh goods Herba Cistanches medicinal material major part effective component is its fresh goods science not in juice in its slag
Medication and health care product exploitation provide foundation.
Application No. is 200910222224.6 patents of invention to disclose " fresh goods Herba Cistanches juicing extractive technique ", by fresh desert
Rong select net system, juicing, alcohol extracting (water mentions), filtering, merge after alcohol extracting (water mentions), filtering again twice extracting solution, concentration,
Cream out.It is extracted using fresh goods, the good fresh desert cistanche of net system is squeezed the juice with juice extractor, extractor is then transferred to, certain
Soak extraction is carried out under temperature and time；During the extraction process, since previously fresh goods Herba Cistanches being squeezed the juice, so increasing
The contacts area of extract Herba Cistanches and solvent；Therefore reduce extraction time, reduce required solvent during soak extraction
Amount, save the cost (in particular with alcohol extracting)；Be conducive to the precipitation of effective ingredient in extract, improve paste-forming rate.
There is presently no the technical reports of discovery preparation Herba Cistanches juicing.The processing of Herba Cistanches only makes and does this method,
It is used as medicine with desert cistanche dry product.Deep processing is only limitted to effective component extracting, especially extracts by raw material of dried product, patent
200910222224.6 extract by raw material juicing immersion of fresh desert cistanche, although having subtracted, fresh goods Herba Cistanches are dry, profit system, cut
The intermediate steps such as piece, drying reduce in extraction process although juicing increases the contact area of extract Herba Cistanches and solvent
The usage amount of solvent and extraction time, but gained desert cistanche juice active constituent content is lower, still falls within the extraction of effective component
Scope.
Summary of the invention
It is an object of the invention to solve the deficiencies in the prior art, raw material availability and production efficiency are improved, improves meat desert
The recovery rate of effective component in Rong reduces production cost, develops extraction and the Herba Cistanches product of a kind of Herba Cistanches effective component
Production method.
The technical scheme is that a kind of extraction of Herba Cistanches effective component and the production method of product, excavation it is new
Fresh meat desert cistanche or drying Herba Cistanches rehydration, it is cleaned, broken, squeeze, filter, being concentrated, purifying Herba Cistanches effective component is pure
Product；Herba Cistanches product is made with the Herba Cistanches juice that squeezing obtains, the Herba Cistanches product includes Herba Cistanches juice, Herba Cistanches concentration
Juice, Herba Cistanches drink, desertliving cistanche wine, Herba Cistanches fine powder and product, Herba Cistanches probiotics fermention product；The Herba Cistanches effectively at
Dividing is benzyl carbinol glycoside.
A kind of production method of Herba Cistanches juice is squeezed using multistage sequence, comprising the following steps:
1) fresh herba cistanches excavated or the cleaning of the herba cistanches of drying rehydration are crushed, and obtain meat desert into the first juice extractor
The first squeezing juice of Rong and Herba Cistanches slag, this Herba Cistanches slag are known as a slag；One slag is sent in the infiltration apparatus one with stirring；It is described
It is broken refer to fresh herba cistanches are crushed to particle of the granularity less than 1 centimetre；
2) while stirring into infiltration apparatus one plus water, infiltrate a slag, amount of water, which is subject to, to be scooped up pomace and has water leaching lower,
Then it delivers into the second juice extractor and obtains the second squeezing juice and two slags；Two slags are sent in the infiltration apparatus two with stirring；
3) while stirring into infiltration apparatus two plus water, infiltrate two slags, amount of water, which is subject to, to be scooped up pomace and has under water droplet,
Then it delivers into third juice extractor and obtains third squeezing juice and three slags；Three slags are sent in the infiltration apparatus three with stirring；
4) while stirring into infiltration apparatus three plus water, amount of water, which is subject to, to be scooped up pomace and has water exudation, then convey into
Enter the 4th juice extractor and obtains the 4th squeezing juice and four slags；Four slags are sent in the infiltration apparatus four with stirring；
5) while stirring into infiltration apparatus four plus water, amount of water, which is subject to, to be scooped up pomace and has water exudation, then convey into
Enter the 5th juice extractor and obtains the 5th squeezing juice and five slags；
6) according to said method, enter the n-th squeezing juice and n slag of juice extractor after the (n-1)th slag adds water；If through detecting n slag
In benzyl carbinol glycoside content be greater than total content 0.1-10% when, then continue above-mentioned rehydration squeezing process, until residue in
Benzyl carbinol glycoside content is less than the 0.1-10% of total content；
Further, the ratio of the pomace and institute's amount of water is respectively a slag weight: amount of water=1:1-1:2, two slags
Weight: amount of water=1:1-1:2, three slag weight: amount of water=1:0.5-1:1.5, four slag weight: amount of water=1:0.5-1:1,
Five slags and later each slag: amount of water all=1:0.5；
Further, the ratio of the pomace and amount of water is respectively a slag weight: amount of water=1:1, two slag weight:
Amount of water=1:1, three slag weight: amount of water=1:0.8, four slag weight: five slags and later each slag: amount of water=1:0.5 adds water
Measure all=1:0.5；
7) by the first squeezing juice of Herba Cistanches, the second squeezing juice, third squeezing juice, the 4th squeezing juice, the 5th squeezing juice ...
With the n-th squeezing juice merge, digest, filter Herba Cistanches squeeze mixed juice again；
8) Herba Cistanches that step 7) obtains are squeezed into mixed juice again and are concentrated to give Herba Cistanches juice；
Alternatively, the second squeezing juice, third squeezing juice, the 4th squeezing juice, the 5th squeezing juice ... and the n-th squeezing juice are merged
Be concentrated into afterwards benzyl carbinol glycoside content close or equal in Herba Cistanches Normal juice content and Normal juice merge enzymatic hydrolysis and filter up to meat desert
Rong's juice.
Further, the n is the series of Multistage squeezing, is one in 1,2,3,4,5,6,7,8,9 ... n.
When n is equal to m, indicate to carry out m squeezing.
In addition to afterbody press residue, broken Herba Cistanches can also be added in above-mentioned press residues at different levels.
It is maximum that the resulting Herba Cistanches of the method squeeze mixed juice quantity again, but effective component concentration is minimum, and in residue effectively
Component content is minimum, and raw material utilization is most abundant, but increases the cost of concentration.
In the above-mentioned methods, other at different levels in addition to the first, second squeezing juice using single-stage or multistage reverse infiltration squeezing
Squeezing juice inversely can mix infiltration with higher level's press residue, and the press residue infiltrated does not add water；By inversely infiltrating squeezing most
Resulting squeezing juice and other sequence squeezing juices at different levels merge afterwards, then digest, filter Herba Cistanches squeeze mixed juice again；Herba Cistanches
Mixed juice is squeezed again is concentrated to give Herba Cistanches juice；Above-mentioned afterbody squeezing juice is inversely and the press residue of prime mixes infiltration；Or it is multistage
Press residue adds the resulting squeezing juice of water infiltration squeezing inversely to mix infiltration with higher level's press residue together respectively；In the Herba Cistanches juice
Benzyl carbinol glycoside content be Herba Cistanches in benzyl carbinol glycoside total amount 10-100%.
Further, it is inversely to infiltrate step by step that the single-stage, which inversely infiltrates, and n-1 slag adds resulting n-th pressure of water infiltration squeezing
Juicing is reverse and the mixing infiltration of n-2 slag, resulting (n-1)th squeezing juice of squeezing inversely mix infiltration, squeezing gained with n-3 press residue
The n-th -2 squeezing juice inversely mix infiltration with upper level press residue ..., four slags are by resulting 5th squeezing of reverse infiltration squeezing
Juice inversely mixes infiltration with two slags, squeezes resulting third squeezing juice with the mixing infiltration of three slags, resulting 4th squeezing juice of squeezing
Infiltration inversely is mixed with a slag, last slag squeezes resulting second squeezing juice and Normal juice merges, and then digests, filters to obtain meat desert
Rong squeezes mixed juice again.The Herba Cistanches that the method obtains squeeze mixed juice minimum number again, but concentration highest.
Further, the reverse infiltration of the multistage is that n-1 slag adds water infiltration to squeeze resulting n-th squeezing juice and n-2 slag
Adding water infiltration to squeeze, resulting (n-1)th squeezing juice is reverse and the mixing infiltration of n-3 press residue, resulting n-th -2 squeezing juice of squeezing are inverse
Infiltration is mixed to upper level press residue ..., four slags squeeze resulting 5th squeezing juice by reverse infiltration and inversely mix with three slags
Infiltration squeezes resulting 4th squeezing juice inversely and the mixing infiltration of two slags, two slags after infiltration squeezes resulting third squeezing juice
The mixing infiltration of a reverse and slag, last resulting second squeezing juice and Normal juice merge, then digest, filter Herba Cistanches squeeze mix again
Close juice.One slag, which squeezes resulting Herba Cistanches and squeezes again, mixes that juice concentration is relatively high, and last residue active constituent content is relatively low.
Further, the reverse infiltration of the multistage is that n-1 slag adds resulting n-th squeezing juice of water infiltration squeezing, n-2 slag to add
Water infiltration squeezes resulting (n-1)th squeezing juice and n-3 press residue add water infiltration squeeze resulting n-th -2 squeezing juice together inversely with
The mixing infiltration ... of n-4 press residue, four slags squeeze resulting 5th squeezing juice inversely by inversely infiltration and three slags mix infiltration, pressure
It squeezes resulting 4th squeezing juice inversely to infiltrate with the mixing of two slags, squeezes resulting third Asia juicing and inversely infiltrated with slag mixing,
One slag squeezes resulting second squeezing juice and Normal juice merges, then digest, filter Herba Cistanches squeeze mixed juice again.Last residue
Active constituent content is relatively low, and raw material utilization is more abundant.
When being greater than 0.1-the 10% of total content through the benzyl carbinol glycoside content in detection n slag, Herba Cistanches in a slag are reduced
Additive amount or the amount of water for increasing subsequent each slag, until the benzyl carbinol glycoside content in residue is less than the 0.1-10% of total content.
Further, the n is the series of Multistage squeezing, is one in 1,2,3,4,5,6,7,8,9 ... n.Work as n
When equal to 5, indicate to carry out five squeezings.
In addition to afterbody press residue, above-mentioned press residues at different levels can also be mixed with broken Herba Cistanches.
When the reverse infiltration is squeezed, infiltration press residues at different levels add water inventory control at 1-5 times of the quantity of slag.
Further, the infiltration press residue at different levels adds water inventory control at 2 times of the quantity of slag.
Dry product Herba Cistanches whole is first cleaned, and reusable heat water carries out immersion rehydration, is crushed, and is then squeezed with above-mentioned multistage sequence
Or Herba Cistanches juice is made in the method for multistage reverse infiltration squeezing.
The cleaning of fresh goods herba cistanches is crushed, and is then first inoculated with probiotics fermention 1-48 hours, is squeezed with above-mentioned multistage sequence
Or the method for multistage reverse infiltration squeezing is made Herba Cistanches juice, benzyl carbinol glycoside content highest, the content polar region in residue.
Dry product Herba Cistanches whole is first cleaned, and reusable heat water carries out immersion rehydration, is crushed, and probiotics fermention 1- is then first inoculated with
48 hours, Herba Cistanches juice is made with the method for above-mentioned multistage sequence squeezing or multistage reverse infiltration squeezing.
The content of benzyl carbinol glycoside in the Herba Cistanches juice is the 10-100% of benzyl carbinol glycoside total amount in Herba Cistanches.
Above-mentioned Herba Cistanches Normal juice is the first squeezing juice.
The Herba Cistanches squeeze mixed juice again or Herba Cistanches juice is concentrated up to Herba Cistanches inspissated juice.
Inspissated juice is by purifying to obtain Herba Cistanches effective component sterling.
Mixed juice is squeezed again with Herba Cistanches juice or Herba Cistanches to be added in other fruit juice, corn bean plasmoid humor or their fermentation liquid
It is one or more, deploy be made Herba Cistanches beverage.
Herba Cistanches juice is concentrated, and water and other raw materials (Chinese medicines such as fructus lycii of dual-purpose of drug and food, cereal, edible mushroom etc.) is added
Extracting solution or the slurries of preparation, which are deployed, is made Herba Cistanches oral solution or beverage.
Using Herba Cistanches juice and white wine or edible alcohol as raw material, other Chinese medical extracts, functionality can be added or not added
Ingredient and auxiliary material are formulated, post-process, filling obtained desertliving cistanche wine.
One or more of mixed juice is squeezed again with Herba Cistanches juice, Herba Cistanches, adds or do not add other Chinese medical extracts,
Through composition adjustment, it is fermented to be inoculated with saccharomyces cerevisiae, is added other function ingredient and auxiliary material, and formulated, post-processing filling is made
Desertliving cistanche wine.
Further, the alcoholic strength of the desertliving cistanche wine is 3 ° -65 °.
Further, the functional components are oligosaccharide, polyphenol, anthocyanidin, protocatechuic acid, ferulic acid, superoxides
One or more of mutase, γ-aminobutyric acid, chlorogenic acid, flavones, resveratrol, saponin(e.
Further, the post-processing refers to the stabilization processes such as lower glue, freezing, ageing Aging storage, filtering.
Herba Cistanches juice or Herba Cistanches squeeze again mixed juice it is concentrated, it is dry, crush be made Herba Cistanches fine powder.
Other functional components and auxiliary material are added in Herba Cistanches fine powder Herba Cistanches effervescent tablet is further made, chewable tablets, contains
Piece, particle electuary or capsule.
Further, the functional components are oligosaccharide, polyphenol, anthocyanidin, protocatechuic acid, ferulic acid, superoxides
One or more of mutase, γ-aminobutyric acid, flavones, resveratrol, saponin(e.
Further, the drying is one of spray drying, vacuum freeze drying, vacuum drying, heated-air drying.
Mixed juice is squeezed again with Herba Cistanches Normal juice, Herba Cistanches, Herba Cistanches juice, inversely squeezes resulting second squeezing juice, meat desert
One of Rong's inspissated juice or a variety of mixing, one or many inoculation probiotics are fermented after composition adjustment, ageing obtains meat
Desert cistanche probiotics fermention product.
Further, above-mentioned hot water preparation and probiotics fermention keep the temperature with solar energy or air source heat pump, earth source heat pump and are
Heat source.
Further, the Herba Cistanches probiotics fermention product is Herba Cistanches ferment, Herba Cistanches vinegar, Herba Cistanches fermentation drink
Material.
Further, the composition adjustment be added water, syrup, other juice, edible mushroom juice, cereal slurries,
One or more of the Chinese herbal medicine extract, or add other functional components, auxiliary material again etc..
Further, the probiotics be saccharomyces cerevisiae, it is bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, short
Bifidobacterium, bifidobacterium infantis, bifidobacterium longum, bacillus coagulans, Lactobacillus casei, Lactobacillus crispatus, Bulgaria
Lactobacillus, bacillus cereus, Lactobacillus delbrueckii cream subspecies, lactobacillus fermenti, lactobacillus gasseri, Lactobacillus helveticus, Yue Shi cream
Bacillus, lactobacillus paracasei, Kluyveromyces fragilis, lactobacillus reuteri, Lactobacillus rhamnosus, bacillus subtilis, saliva
The bright beading of lactobacillus, streptococcus thermophilus, lactobacillus plantarum, bacillus licheniformis, lactobacillus paracasei, lactobacillus acidophilus, goldbeater's skin
One or more of bacterium goldbeater's skin subspecies, kluyveromyces marxianus, Pediococcus acidilactici, acetic acid bacteria, Pediococcus pentosaceus.
It is mixed with Herba Cistanches and other raw materials, is inoculated with probiotics post-fermentation 1-48 hours, squeezes the juice, further after broken
It is inoculated with probiotics fermention and Herba Cistanches fermented product is made.
Further, other described raw materials are fruits and vegetables, Chinese herbal medicine, mushroom, the flower of edible plant, fruit, root, stem, Ye Zhong
One kind and it is several.
Invention achieves following effects:
Herba Cistanches of the present invention, which are extracted, realizes continuous operations, replaces traditional herbal medicine immersion to extract with quick infiltration, squeezing
Technique, juicing used time are 20-the 30% of the prior art and traditional Chinese medicine extractive technique, and production efficiency improves 3-5 times.
According to the prior art, the effective components such as benzyl carbinol glycoside, polysaccharide in Herba Cistanches content in squeezing juice is seldom, absolutely
Major part is all in press residue, but the benzyl carbinol glycosides of the present invention overwhelming majority are transferred in Herba Cistanches juice, have accomplished raw material
Make full use of.
Production cost of the present invention is greatly lowered.
Output of the present invention is big, and Herba Cistanches crushing juice rate is high, and yield is high, and residue active constituent content is low.
The present invention either fresh goods Herba Cistanches or dry product Herba Cistanches first carry out probiotics fermention and squeeze again, Herba Cistanches pressure
Squeezing series is few, and the content of the stupid ethyl alcohol glycosides of gained Herba Cistanches juice is higher, effectively reduces Pressing Number, reduces production cost.And
Made from the method on the basis of Herba Cistanches juice Herba Cistanches drink obtained, wine, probiotics fermention product taste and flavor
More preferably.
Figure of description
Attached drawing 1 is the process flow chart of embodiment 1；
Attached drawing 2 is the process flow chart of embodiment 2；
Attached drawing 3 is the process flow chart of embodiment 3；
Attached drawing 4 is the process flow chart of embodiment 4；
Attached drawing 5 is the process flow chart of embodiment 5.
Specific embodiment
Embodiment 1
1) fresh herba cistanches excavated or the cleaning of the herba cistanches of drying rehydration are crushed, and obtain meat desert into the first juice extractor
Rong's Normal juice and Herba Cistanches slag, this Herba Cistanches slag are known as a slag；One slag is sent in the infiltration apparatus one with stirring；
2) while stirring into infiltration apparatus one plus water, infiltrate a slag, amount of water, which is subject to, to be scooped up pomace and has water leaching lower,
Then it delivers into the second juice extractor and obtains the second squeezing juice and two slags；Two slags are sent in the infiltration apparatus two with stirring；
3) while stirring into infiltration apparatus two plus water, infiltrate two slags, amount of water, which is subject to, to be scooped up pomace and has under water droplet,
Then it delivers into third juice extractor and obtains third squeezing juice and three slags；Three slags are sent in the infiltration apparatus three with stirring；
4) while stirring into infiltration apparatus three plus water, amount of water, which is subject to, to be scooped up pomace and has water exudation, then convey into
Enter the 4th juice extractor and obtains the 4th squeezing juice and four slags；Four slags are sent in the infiltration apparatus four with stirring；
5) while stirring into infiltration apparatus four plus water, amount of water, which is subject to, to be scooped up pomace and has water exudation, then convey into
Enter the 5th juice extractor and obtains the 5th squeezing juice and five slags；
The ratio for controlling pomace and institute's amount of water is respectively a slag weight: amount of water=1:1-1:2, two slag weight: adds water
Amount=1:1-1:2, three slag weight: amount of water=1:0.5-1:1.5, four slag weight: amount of water=1:0.5-1:1；
6) Herba Cistanches Normal juice, the second squeezing juice, third squeezing juice, the 4th squeezing juice, the 5th squeezing juice are merged, enzymatic hydrolysis,
Filter Herba Cistanches squeeze mixed juice again；
7) the multiple squeezing mixed juice for obtaining step 6) is concentrated up to Herba Cistanches juice；Or by the second squeezing juice, third squeezing juice,
4th squeezing juice, the 5th squeezing juice are concentrated after merging, and then merge enzymatic hydrolysis with Normal juice and filter up to Herba Cistanches juice.
The content of the benzyl carbinol glycoside in the Herba Cistanches juice of concentration is controlled as the benzyl carbinol glycoside total amount in Herba Cistanches raw material
10-100%.
Inspissated juice is by purifying to obtain Herba Cistanches effective component sterling.
Embodiment 2
1) fresh herba cistanches excavated or the cleaning of the herba cistanches of drying rehydration are crushed, and obtain meat desert into the first juice extractor
Rong's Normal juice and Herba Cistanches slag, this Herba Cistanches slag are known as a slag；One slag is sent in the infiltration apparatus one with stirring；
2) add broken Herba Cistanches and third squeezing juice into infiltration apparatus one while stirring, infiltrate a slag, it is then defeated
It is fed into the second juice extractor and obtains the second squeezing juice and two slags；Two slags are sent in the infiltration apparatus two with stirring；Second squeezing juice
Merge to squeeze mixed juice again with Normal juice；
3) add broken Herba Cistanches and the 4th squeezing juice into infiltration apparatus two while stirring, infiltrate two slags, it is then defeated
It is fed into third juice extractor and obtains third squeezing juice and three slags；Three slags are sent in the infiltration apparatus three with stirring；
4) add such as the 5th squeezing juice into infiltration apparatus three while stirring, then deliver into the 4th juice extractor and obtain the 4th pressure
Juicing and four slags；Four slags are sent in the infiltration apparatus four with stirring；
5) while stirring into infiltration apparatus four plus water, amount of water, which is subject to, to be scooped up pomace and has water exudation, controls four slag weights
Amount: then amount of water=1:0.5-1:1 delivers into the 5th juice extractor and obtains the 5th squeezing juice and five slags；
6) mixed juice enzymatic hydrolysis is squeezed again, is filtered up to Herba Cistanches juice, and concentration both obtains Herba Cistanches inspissated juice.
The content of the benzyl carbinol glycoside in the Herba Cistanches juice of concentration is controlled as the benzyl carbinol glycoside total amount in Herba Cistanches raw material
10-100%.
Inspissated juice is by purifying to obtain Herba Cistanches effective component sterling.
Embodiment 3
1) fresh herba cistanches excavated or the cleaning of the herba cistanches of drying rehydration are crushed, and obtain meat desert into the first juice extractor
Rong's Normal juice and Herba Cistanches slag, this Herba Cistanches slag are known as a slag；One slag is sent in the infiltration apparatus one with stirring；
2) add broken Herba Cistanches and third squeezing juice into infiltration apparatus one while stirring, infiltrate a slag, it is then defeated
It is fed into the second juice extractor and obtains the second squeezing juice and two slags；Two slags are sent in the infiltration apparatus two with stirring；Second squeezing juice
Merge to squeeze mixed juice again with Normal juice；
3) broken Herba Cistanches and the 4th squeezing juice, the 5th squeezing juice are added into infiltration apparatus two while stirring, make two
Slag infiltration, then delivers into third juice extractor and obtains third squeezing juice and three slags；Three slags are sent to the infiltration apparatus three with stirring
In；
4) while stirring into infiltration apparatus three plus water, amount of water, which is subject to, to be scooped up pomace and has water exudation, three slag weight: is added
Then water=1:0.5-1:1.5 delivers into the 4th juice extractor and obtains the 4th squeezing juice and four slags；Four slags are sent to stirring
In infiltration apparatus four；
5) while stirring into infiltration apparatus four plus water, amount of water, which is subject to, to be scooped up pomace and has water exudation, controls four slag weights
Amount: then amount of water=1:0.5-1:1 delivers into the 5th juice extractor and obtains the 5th squeezing juice and five slags；
6) mixed juice enzymatic hydrolysis is squeezed again, is filtered up to Herba Cistanches juice, and concentration both obtains Herba Cistanches inspissated juice.
The content of the benzyl carbinol glycoside in the Herba Cistanches juice of concentration is controlled as the benzyl carbinol glycoside total amount in Herba Cistanches raw material
10-100%.
Inspissated juice is by purifying to obtain Herba Cistanches effective component sterling.
Embodiment 4
1) fresh herba cistanches excavated or the cleaning of the herba cistanches of drying rehydration are crushed, and obtain meat desert into the first juice extractor
Rong's Normal juice and Herba Cistanches slag, this Herba Cistanches slag are known as a slag；One slag is sent in the infiltration apparatus one with stirring；
2) add broken Herba Cistanches and third, the four, the 5th squeezing juices into infiltration apparatus one while stirring, soak a slag
Profit, then delivers into the second juice extractor and obtains the second squeezing juice and two slags；Two slags are sent in the infiltration apparatus two with stirring；The
Two squeezing juices and Normal juice merge to squeeze mixed juice again；
3) water is added into infiltration apparatus two while stirring, make two slags infiltrate, amount of water with scoop up pomace have water exudation be
Standard, two slag weight: then amount of water=1:1-1:2 delivers into third juice extractor and obtains third squeezing juice and three slags；The transmission of three slags
Into the infiltration apparatus three with stirring；
4) while stirring into infiltration apparatus three plus water, amount of water, which is subject to, to be scooped up pomace and has water exudation, three slag weight: is added
Then water=1:0.5-1:1.5 delivers into the 4th juice extractor and obtains the 4th squeezing juice and four slags；Four slags are sent to stirring
In infiltration apparatus four；
5) while stirring into infiltration apparatus four plus water, amount of water, which is subject to, to be scooped up pomace and has water exudation, controls four slag weights
Amount: then amount of water=1:0.5-1:1 delivers into the 5th juice extractor and obtains the 5th squeezing juice and five slags；
6) mixed juice enzymatic hydrolysis is squeezed again, is filtered up to Herba Cistanches juice, and concentration both obtains Herba Cistanches inspissated juice.
The content of the benzyl carbinol glycoside in the Herba Cistanches juice of concentration is controlled as the benzyl carbinol glycoside total amount in Herba Cistanches raw material
10-100%.
Inspissated juice is by purifying to obtain Herba Cistanches effective component sterling.
Embodiment 5
1) fresh herba cistanches excavated or the cleaning of the herba cistanches of drying rehydration are crushed, and obtain meat desert into the first juice extractor
Rong's Normal juice and Herba Cistanches slag, this Herba Cistanches slag are known as a slag；One slag is sent in the infiltration apparatus one with stirring；
2) broken Herba Cistanches and third, the 4th squeezing juice are added into infiltration apparatus one while stirring, infiltrate a slag,
Then it delivers into the second juice extractor and obtains the second squeezing juice and two slags；Two slags are sent in the infiltration apparatus two with stirring；Second
Squeezing juice and Normal juice merge to squeeze mixed juice again；
3) it is added while stirring into infiltration apparatus two into broken Herba Cistanches and the 5th squeezing juice, infiltrates two slags, so
After deliver into third juice extractor and obtain third squeezing juice and three slags；Three slags are sent in the infiltration apparatus three with stirring；
4) while stirring into infiltration apparatus three plus water, amount of water, which is subject to, to be scooped up pomace and has water exudation, three slag weight: is added
Then water=1:0.5-1:1.5 delivers into the 4th juice extractor and obtains the 4th squeezing juice and four slags；Four slags are sent to stirring
In infiltration apparatus four；
5) while stirring into infiltration apparatus four plus water, amount of water, which is subject to, to be scooped up pomace and has water exudation, controls four slag weights
Amount: then amount of water=1:0.5-1:1 delivers into the 5th juice extractor and obtains the 5th squeezing juice and five slags；
6) mixed juice enzymatic hydrolysis is squeezed again, is filtered up to Herba Cistanches juice, and concentration both obtains Herba Cistanches inspissated juice.
The content of the benzyl carbinol glycoside in the Herba Cistanches juice of concentration is controlled as the benzyl carbinol glycoside total amount in Herba Cistanches raw material
10-100%.
Inspissated juice is by purifying to obtain Herba Cistanches effective component sterling.
Embodiment 6
The cleaning of fresh goods herba cistanches is crushed, and is then inoculated with probiotics fermention 1-48 hours, is obtained with the method for embodiment 1-5
To Herba Cistanches juice and Herba Cistanches inspissated juice.
Embodiment 7
Dry product Herba Cistanches whole is first cleaned, and reusable heat water carries out immersion rehydration, is crushed, and probiotics fermention 1- is then first inoculated with
48 hours, Herba Cistanches juice and Herba Cistanches inspissated juice were obtained with the method for embodiment 1-5.
Embodiment 8
The Herba Cistanches juice or Herba Cistanches obtained in each embodiment of above-mentioned 1-5 squeezes in mixed juice again and other fruit juice, cereal is added
One of beans slurries or their fermentation liquid are a variety of, deploy and Herba Cistanches beverage is made.
Embodiment 9
It is concentrated in the Herba Cistanches juice that each embodiment of above-mentioned 1-5 obtains, water and other raw materials (fructus lycii of dual-purpose of drug and food is added
Equal Chinese medicines, cereal, edible mushroom etc.) extracting solution or the slurries of preparation deploy Herba Cistanches oral solution or beverage be made.
Embodiment 10
Each embodiment of above-mentioned 1-5 obtain using Herba Cistanches juice and white wine or edible alcohol as raw material, can add or not add
Add the stabilization processes, ageing after-ripening such as other Chinese medical extracts, functional components and formulated, formulated, the lower glue of auxiliary material, freezing
Processing, filtering, filling obtained desertliving cistanche wine, the alcoholic strength for controlling desertliving cistanche wine is 3 ° -65 °.Functional components used are oligomeric
Sugar, polyphenol, anthocyanidin, protocatechuic acid, ferulic acid, superoxide dismutase, γ-aminobutyric acid, chlorogenic acid, flavones, white black false hellebore
One or more of alcohol, saponin(e.
Embodiment 11
The Herba Cistanches juice that is obtained with each embodiment of above-mentioned 1-5, Herba Cistanches squeeze one or more of mixed juice again, addition or
Other Chinese medical extracts are not added, through composition adjustment, inoculation saccharomyces cerevisiae is fermented, other function ingredient and auxiliary material is added,
The stabilization processes such as formulated, lower glue, freezing, ageing Aging storage, filtering, filling obtained desertliving cistanche wine.Functionality used
Ingredient is oligosaccharide, polyphenol, anthocyanidin, protocatechuic acid, ferulic acid, superoxide dismutase, γ-aminobutyric acid, chlorogenic acid, Huang
One or more of ketone, resveratrol, saponin(e.
Embodiment 12
The Herba Cistanches juice or Herba Cistanches obtained with each embodiment of above-mentioned 1-5 squeeze again mixed juice it is concentrated, it is dry, crush be made
Herba Cistanches fine powder.The drying is one of spray drying, vacuum freeze drying, vacuum drying, heated-air drying.
Other functional components and auxiliary material are added in above-mentioned Herba Cistanches fine powder, Herba Cistanches effervescent tablet, chewing is further made
Piece, lozenge, particle electuary or capsule.Functional components used are oligosaccharide, polyphenol, anthocyanidin, protocatechuic acid, ferulic acid, surpass
One or more of superoxide dismutase, γ-aminobutyric acid, flavones, resveratrol, saponin(e.
Embodiment 13
The Herba Cistanches Normal juice that is obtained with each embodiment of above-mentioned 1-5, Herba Cistanches squeeze mixed juice, Herba Cistanches juice, reverse squeezing again
One of resulting second squeezing juice, Herba Cistanches inspissated juice or a variety of mixing, one or many inoculation benefits after composition adjustment
Raw bacterium is fermented, ageing obtains Herba Cistanches probiotics fermention product.Herba Cistanches probiotics fermention product is Herba Cistanches ferment, meat desert
Rong's vinegar, Herba Cistanches fermented beverage.
In hot water preparation and probiotics fermention heat preservation using solar energy or air source heat pump, earth source heat pump as heat source.
Be added when composition adjustment water, syrup, other juice, edible mushroom juice, cereal slurries, in the Chinese herbal medicine extract
One or more, or add other functional components, auxiliary material again etc..
Fermentation probiotics used is saccharomyces cerevisiae, bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, short pair
Discrimination bacillus, bifidobacterium infantis, bifidobacterium longum, bacillus coagulans, Lactobacillus casei, Lactobacillus crispatus, bulgarian milk
Bacillus, bacillus cereus, Lactobacillus delbrueckii cream subspecies, lactobacillus fermenti, lactobacillus gasseri, Lactobacillus helveticus, Yue Shi cream bar
Bacterium, lactobacillus paracasei, Kluyveromyces fragilis, lactobacillus reuteri, Lactobacillus rhamnosus, bacillus subtilis, saliva cream
Bacillus, streptococcus thermophilus, lactobacillus plantarum, bacillus licheniformis, lactobacillus paracasei, lactobacillus acidophilus, Leuconostoc mesenteroides
One or more of goldbeater's skin subspecies, kluyveromyces marxianus, Pediococcus acidilactici, acetic acid bacteria, Pediococcus pentosaceus.
Embodiment 14
It is mixed, is inoculated with probiotics post-fermentation 1-48 hours after broken, with above-described embodiment 1-5 with Herba Cistanches and other raw materials
Method squeeze the juice, further be inoculated with probiotics fermention be made Herba Cistanches fermented product.Other raw materials be fruits and vegetables, Chinese herbal medicine,
One of mushroom, the flower of edible plant, fruit, root, stem, leaf are a variety of.
Fermentation probiotics used is saccharomyces cerevisiae, bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, short pair
Discrimination bacillus, bifidobacterium infantis, bifidobacterium longum, bacillus coagulans, Lactobacillus casei, Lactobacillus crispatus, bulgarian milk
Bacillus, bacillus cereus, Lactobacillus delbrueckii cream subspecies, lactobacillus fermenti, lactobacillus gasseri, Lactobacillus helveticus, Yue Shi cream bar
Bacterium, lactobacillus paracasei, Kluyveromyces fragilis, lactobacillus reuteri, Lactobacillus rhamnosus, bacillus subtilis, saliva cream
Bacillus, streptococcus thermophilus, lactobacillus plantarum, bacillus licheniformis, lactobacillus paracasei, lactobacillus acidophilus, Leuconostoc mesenteroides
One or more of goldbeater's skin subspecies, kluyveromyces marxianus, Pediococcus acidilactici, acetic acid bacteria, Pediococcus pentosaceus.
Although technical solution of the present invention is described in above-described embodiment, one skilled in the art would recognize that
On the premise of without departing from the spirit and scope of the present invention, the present invention can be variously changed and is modified, result all exists
Within protection scope of the present invention.
Claims (9)
1. a kind of extraction of Herba Cistanches effective component and the production method of product, the fresh herba cistanches of excavation or drying Herba Cistanches
Rehydration, it is cleaned, broken, squeeze, filter, being concentrated, purifying and to obtain Herba Cistanches effective component sterling；The Herba Cistanches juice obtained with squeezing
Herba Cistanches product is made, the Herba Cistanches product includes Herba Cistanches juice, Herba Cistanches inspissated juice, Herba Cistanches drink, desertliving cistanche wine, meat
Desert cistanche fine powder and product, Herba Cistanches probiotics fermention product；The Herba Cistanches effective component is benzyl carbinol glycoside and polysaccharide.
2. a kind of production method of Herba Cistanches juice, it is characterised in that the squeezing juice obtained with claim 1 squeezing step is through handling
It obtains, comprising the following steps:
1) fresh herba cistanches excavated or drying Herba Cistanches rehydration, it is cleaned, broken, the first squeezing juice is obtained i.e. into juice extractor
Herba Cistanches Normal juice and Herba Cistanches slag, this Herba Cistanches slag are known as a slag；
2) slag squeezes to obtain the second squeezing juice and two slags after adding flooding；
3) two slags squeeze to obtain third squeezing juice and three slags after adding flooding；
4) three slags squeeze to obtain the 4th squeezing juice and four slags after adding flooding；
5) four slags squeeze to obtain the 5th squeezing juice and five slags after adding flooding；
6) the n-th squeezing juice and n slag according to said method, are squeezed to obtain after the (n-1)th slag adds flooding；
7) by the first squeezing juice of Herba Cistanches, the second squeezing juice, third squeezing juice, the 4th squeezing juice, the 5th squeezing juice ... and n-th
Squeezing juice merge, digest, filter Herba Cistanches squeeze mixed juice again；
8) Herba Cistanches that step 7) obtains are squeezed into mixed juice again and are concentrated to give Herba Cistanches juice；Or by the second squeezing juice, third squeezing juice,
4th squeezing juice, the 5th squeezing juice ... and the n-th squeezing juice are concentrated into benzyl carbinol glycoside content close or equal to Normal juice after merging
In content and Normal juice merge enzymatic hydrolysis, filter up to Herba Cistanches juice；
The content of benzyl carbinol glycoside in the Herba Cistanches juice is the 10-100% of benzyl carbinol glycoside total amount in Herba Cistanches；
The n is the series of Multistage squeezing, is any one in 2,3,4,5,6,7,8,9 ... n；
The series of the Multistage squeezing is 5, a slag, two slags and broken Herba Cistanches mixing.
3. a kind of production method of Herba Cistanches juice, it is characterised in that remove first, second squeezing juice in claim 2
Outside, other squeezing juices at different levels inversely can mix extraction with higher level's press residue, and the press residue being leached does not add water；By reverse
Last resulting squeezing juice is squeezed in extraction and other sequence squeezing juices at different levels merge, then digest, filter Herba Cistanches squeeze mix again
Juice is closed, Herba Cistanches squeeze mixed juice again and are concentrated to give Herba Cistanches juice；The content of benzyl carbinol glycoside in the Herba Cistanches juice is Herba Cistanches
The 10-100% of middle benzyl carbinol glycoside total amount.
4. a kind of production method of Herba Cistanches juice, it is characterised in that it is small that broken Herba Cistanches are first inoculated with probiotics fermention 1-48
When, Herba Cistanches juice then is made by method described in claim 2 or 3.
5. a kind of Herba Cistanches inspissated juice squeezes mixed juice or the concentration of Herba Cistanches juice i.e. by claim 2,3 or 4 resulting Herba Cistanches again
Obtain Herba Cistanches inspissated juice.
6. a kind of Herba Cistanches drink is one squeezed again in mixed juice by claim 2,3 or 4 resulting Herba Cistanches juice, Herba Cistanches
Kind, it is concentrated or be not concentrated, deploy, filling obtained Herba Cistanches oral solution or Herba Cistanches beverage that other raw materials are added；Or by right
It is required that Herba Cistanches inspissated juice described in 5 is added water allotment, filling obtained Herba Cistanches oral solution or Herba Cistanches beverage.
7. a kind of desertliving cistanche wine is to squeeze one of mixed juice again with claim 2,3 or 4 resulting Herba Cistanches juice, Herba Cistanches
Or several, white wine or edible alcohol are raw material, add or do not add other Chinese medical extracts, functional components, addition auxiliary material warp
Allotment, post-processing, filling obtained desertliving cistanche wine；Or mixing is squeezed again with claim 2,3 or 4 resulting Herba Cistanches juice, Herba Cistanches
One or more of juice adds or does not add other Chinese medical extracts, and through composition adjustment, inoculation saccharomyces cerevisiae is fermented, adds
Enter other function ingredient and auxiliary material, formulated, post-processing, filling obtained desertliving cistanche wine.
8. a kind of quiet powder of Herba Cistanches and its product, it is characterised in that with claim 2,3,4 or 5 resulting Herba Cistanches juice or meat desert
It is raw material that Rong squeezes one of mixed juice, Herba Cistanches inspissated juice again, concentrated, dry obtained Herba Cistanches fine powder；With above-mentioned meat desert
Rong's fine powder is raw material, and other functional raw materials are added and auxiliary material is process Herba Cistanches effervescent tablet, chewable tablets, lozenge, particle punching
Agent or capsule.
9. a kind of Herba Cistanches probiotics fermention product, it is characterised in that by Herba Cistanches Normal juice described in claim 2,3,4 or 5,
Herba Cistanches one of squeeze mixed juice, Herba Cistanches juice again, inversely squeeze resulting second squeezing juice, Herba Cistanches inspissated juice or more
Kind, one or many inoculation probiotics are fermented after composition adjustment, ageing obtains Herba Cistanches probiotics fermention product；The meat
Desert cistanche probiotics fermention product is Herba Cistanches ferment, Herba Cistanches vinegar, Herba Cistanches fermented beverage；The composition adjustment is to be added
One or more of water, syrup, other juice, edible mushroom juice, cereal slurries, the Chinese herbal medicine extract, functional components；
The functional components are oligosaccharide, polyphenol, anthocyanidin, protocatechuic acid, ferulic acid, superoxide dismutase, gamma-amino fourth
Acid, chlorogenic acid, flavones, resveratrol, saponin(e are one or more.
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| CN115669921A (en) * | 2022-05-20 | 2023-02-03 | 新疆天山北坡冷粮食品有限公司 | Liver-protecting and kidney-protecting cistanche enzyme and preparation method thereof |
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