CN1094368C

CN1094368C - Chinese medicine for treating alopecia

Info

Publication number: CN1094368C
Application number: CN99115875A
Authority: CN
Inventors: 程丁厚
Original assignee: Individual
Current assignee: Individual
Priority date: 1999-10-15
Filing date: 1999-10-15
Publication date: 2002-11-20
Anticipated expiration: 2019-10-15
Also published as: CN1293062A

Abstract

The present invention comprises two groups of medicine recipes of an alopecia regenerating bolus used for oral administration and an alopecia regenerating agent used for coating outside, and the alopecia regenerating bolus and the alopecia regenerating agent are simultaneously used, wherein the alopecia regenerating bolus is prepared from angelica, astragalus root, red sage root, radix-polygoni multiflori, mulberry leaf, bulbus fritilariae, flos magnolia, etc.; the alopecia regenerating agent is prepared from cnidium monnieri seed, stemona, phellodendron, etc. The medicine of the present invention has a special effect on treating alopecia areata, total alopecia, universal alopecia and the alopecia of babies, and has an exact effect on treating seborrheic alopecia, yellow hair, thin hair, etc.

Description

A kind of Chinese medicine for the treatment of alopecia

Content of the present invention belongs to the fabricating technology field of medicine, particularly a kind of medicine of being made by pure Chinese herbal medicine that is used for the treatment of alopecia.

Alopecia is the very high department of dermatologry difficult disease of a kind of sickness rate, and common type has alopecia areata, alopecia totalis, alopecia universalis, baby's alopecia childhood, male pattern alopecia, seborrheic alopecia (comprising oiliness and dryness seborrheic alopecia), congenital alopecia, few send out etc.Concerning the patient, though alopecia does not have fatal risk, the influence beauty treatment, and bring great psychic pain for particularly young and middle-aged patient of patient and women patient.The known clinical medicine that is used for the treatment of alopecia is mainly all kinds of washing and puts preparation on the skin at present, as hair growth tonic, liquid for hair-growth etc., also there are some media to disclose some Chinese medicines (partially) side in recent years from the principle of Chinese medicine blood rearing interpolating kidney, as Alopecia Pill, Rongfa Wan-a medicinal pill, powerful hair tonic, YANGXUE SHENGFA JIAONANG etc., they are controlled executing of alopecia also certain curative effect in some aspects, but generally speaking the clinical cure rate of these medicines is lower, can not effect a permanent cure, and some medicine life-time service also has toxic and side effects to the patient.

The objective of the invention is at the existing in prior technology defective, by excavating the abundant Chinese medicine resource of motherland, and then provide a kind of prescription science, easy to prepare, curative effect is high, the Chinese medicine that is exclusively used in all kinds of alopecias of treatment that has no side effect.

The preparation scheme of Chinese medicine of the present invention comes from the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs thought of motherland's traditional medicine about " treatment must aim at the pathogenesis of disease ", and it is designer of the present invention by medical book is at all times concentrated on studies and developed acquisition through concentrated the summary on the clinical practice basis for many years.Because alopecia mostly is QI and blood deficiency, the kidney channel deficiency, damp and hot going up steamed, disturbing upward of liver-fire because of due to, in view of the above, designer spy filters out from motherland's medical treasure-house has benefiting QI and nourishing blood, expelling wind and removing dampness, nourishing the liver and kidney, the natural plants of function of spleen and stomach regulating effect, by the theory of Chinese medical science side of being prepared into meticulously, comprise in the side simultaneously use in take pill agent and two groups of pharmaceutical formulations of outer obliterating usefulness liquid preparation, wherein, said pill agent is by comprising Radix Angelicae Sinensis, the Radix Astragali, Radix Salviae Miltiorrhizae, the Radix Polygoni Multiflori, Folium Mori, Bulbus Fritillariae Cirrhosae, Flos Magnoliae, Herba Ecliptae, Hippocampus, Flos Carthami, Semen sesami Niger, Rhizoma Gastrodiae processes at interior all herbal medicine raw materials, and said liquid preparation is by comprising Fructus Cnidii, the Radix Stemonae, Cortex Phellodendri, Cacumen Platycladi, ferrosisuifas crudus is obtained through refining through ethanol at interior all herbal medicine raw materials and is formed.The Chinese medicine that is made of above-mentioned two groups of prescriptions that use simultaneously can be given full play to the characteristics of Chinese medicine preparation in clinical practice, it can correct the pathology obstacle, enhance metabolism and the recovery of function, make the tissue of impaired hair follicle of head and devitalization be tending towards normal, and then make hair restoration, reach the purpose for the treatment of both the principal and secondary aspects of a disease.

The medicine material proportioning value that constitutes every part of pill agent among the present invention is: 48～53 unit of weights of Radix Angelicae Sinensis, 57～63 unit of weights of the Radix Astragali, 35～40 unit of weights of Radix Salviae Miltiorrhizae, 55～65 unit of weights of the Radix Polygoni Multiflori, 50～55 unit of weights of Folium Mori, 38～42 unit of weights of Bulbus Fritillariae Cirrhosae, 30～35 unit of weights of Flos Magnoliae, 55～65 unit of weights of Herba Ecliptae, 28～35 unit of weights of Hippocampus, 25～35 unit of weights of Flos Carthami, 45～55 unit of weights of Semen sesami Niger, 38～45 unit of weights of Rhizoma Gastrodiae.The medicine material proportioning value that constitutes every part of liquid preparation of Chinese medicine of the present invention is: 45～50 unit of weights of Fructus Cnidii, 24～27 unit of weights of the Radix Stemonae, 9～11 unit of weights of Cortex Phellodendri, 24～26 unit of weights of Cacumen Platycladi, 1.8～2.2 unit of weights of ferrosisuifas crudus.

Pill among the present invention is as medication for oral administration, and the Radix Angelicae Sinensis master in its prescription goes into liver, spleen, heart channel, have invigorate blood circulation, regulating menstruation, enrich blood, lubricated merit; The Radix Astragali is gone into spleen, lung meridian, has the merit of invigorating the spleen and replenishing QI, strengthening the spleen and stomach; Radix Salviae Miltiorrhizae is gone into the heart, pericardium channel, has the merit of blood circulation promoting and blood stasis dispelling, heat clearing away; The Radix Polygoni Multiflori is gone into spleen, liver, kidney channel, has the merit of spleen reinforcing, the liver benefiting, kidney tonifying, strengthening spleen and nourishing blood; Folium Mori are gone into lung, Liver Channel, have the merit of expelling wind and clearing away heat, liver heat removing and eyesight improving; Bulbus Fritillariae Cirrhosae is gone into lung meridian, has the merit of lung moistening eliminating stagnation, relieving cough and resolving phlegm; Flos Magnoliae is gone into lung meridian, has the merit of expelling wind and cold; Herba Ecliptae goes into liver, kidney channel, has the merit of nourishing the liver and kidney, clearing away heat and cooling blood; Hippocampus goes into kidney channel, has the merit of warming the kidney tonifying YANG, repercussive; Flos Carthami is gone into the heart, Liver Channel, has the merit of promoting blood circulation to remove obstruction in the collateral, blood stasis dispelling; Semen sesami Niger is gone into liver, kidney channel, has the merit of nourishing the liver and kidney, the foster the five internal organs of profit; Rhizoma Gastrodiae is gone into Liver Channel, has the merit of suppressing the hyperactive liver, suppressing liver-wind to relieve spasm.Above-mentioned all medicines share, and can be total in clinical that income gas nourishes blood, the merit of expelling wind and removing dampness, circulation of qi promoting blood stasis dispelling, temperature three-way meridian, nourishing the liver and kidney, function of spleen and stomach regulating, anti-cortex, short regeneration, improve and recovery hair follicle function, and the hair that comes off is regrowed.

Liquid preparation among the present invention is as the outer obliterating medication that is used in combination with pill agent adjustment, and the Fructus Cnidii in its prescription is gone into kidney, tri-jiao channel, has the merit of dispeiling pathogenic wind and removing dampness, killing parasites for relieving itching; The Radix Stemonae is gone into lung meridian, has the merit of killing parasites for relieving itching; Cortex Phellodendri goes into kidney, urinary bladder channel, has heat-clearing and toxic substances removing, eliminating dampness and astringing sores, parasite killing except that effect evil, repellent antipruritic; Cacumen Platycladi returns liver, kidney, large intestine channel, has the merit of clearing away heat and cooling blood detumescence, parasite killing, granulation promoting, defat hair growth promoting; Clear vitriol is gone into liver, spleen channel, has the merit of heat-clearing and toxic substances removing, dampness removing to stop itchin, parasite killing and convergence.Should outer be coated with medication and combine, directly be coated with the stimulation and the efficacy of a drug of putting on the skin, and make the patient be able to space between skin and muscles mediation, QI and blood mediation, internal organs equilibrium between yin and yang, thereby reach the purpose of promoting health and curing diseases, giving birth to beard and hair at disease sites by it with the mass action of pill agent for oral administration.

Compare with domestic and international existing like product, Chinese medicine of the present invention has safety, specially good effect, the advantage that has no side effect, show according to clinical use result, this medicine is in the treatment alopecia areata, alopecia totalis, alopecia universalis, trichorrhexis and infant baldness aspect have special effect, to seborrheic alopecia, yellow hair, the treatment of fine grade also has precise effects, be regarded as the naughty disease of refractory and incurable disease in recent years in treatment hair field with it always, invade the pseudopelade aspect of decreasing due to the hair follicle and obtained obvious progress, treatment to congenital hypotrichosis and hairlessness aspect has obtained breakthrough progress especially, and these all are to have like product at present both at home and abroad now to hardly match.

The preparation method of medicine of the present invention is:

1, ball medicaments preparation---will be thin by formula ratio and the Chinese crude drug raw material difference powder of respectively distinguishing the flavor of after cleaning, cross 120 mesh sieves, mixing is mixed thoroughly, and making pellets by mixing medical powder with honey, every ball nearly weigh 11 grams.

2, the preparation of liquid preparation---will dry after little the washing of Chinese crude drug raw material section of respectively distinguishing the flavor of by formula ratio and 1000～1200 grams of the total restatement after cleaning, pack in the resealable container, ethanol 3500～the 4000ml of adding 75% soaked for two weeks, and filtering-depositing is got its liquid and packing.

Clinical case is observed and curative effect

187 examples of clinical observation case once in development process of the present invention.

One, administrated method: when the patient was treated, pill agent and liquid preparation used simultaneously.Oral pill 2～3 times on the one, each ball (child is cut down according to the circumstance) send down with eliminating cold for resuscitation water on an empty stomach; Liquor is directly embrocated in the affected part, is coated with the back and applies 10～15 minutes with damp and hot towel, so that the efficacy of a drug is imported stimulus information in the body into by meridians, acupuncture points on the human body, promotes the infiltration and the absorption of medicine and produces certain local blood drug level and a therapeutical effect.Medication in per 30 days is one and treats the course of treatment, must note during the treatment not having hair dyed, perming, and washes hair with the big detergent of alkalescence, does not eat irritable food less, avoids direct stimulation and keeps rule of life; The seborrheic alopecia patient should note few food or not eat higher fatty acid, high-carbohydrate food, eat vegetable and fruit more.

Two, criterion of therapeutical effect: divide recovery from illness, effective, invalid three kinds, wherein: the alopecia district all grows hair or only stays 1～2 fine hair district person about 2cm2 to be recovery from illness after medication 2～5 courses of treatment; Alopecia district 50% grows the hair with top, and the person serves as effective; Alopecia district 50% grows hair with the lower part or the sparse pubescence person of growing is only arranged for invalid.

Three, observation of curative effect result: 187 case patients of this group are after treatment, and 175 examples of fully recovering account for 93.6% of total treatment case load, and effective 9 examples account for 4.9%, and invalid 3 examples account for 1.5%, and total effective rate is 98.5%.

Claims

1, a kind of Chinese medicine for the treatment of alopecia is characterized in that it is the medicament of being processed into by following materials of weight proportions: 48～53 unit of weights of Radix Angelicae Sinensis, 57～63 unit of weights of the Radix Astragali, 35～40 unit of weights of Radix Salviae Miltiorrhizae, 55～65 unit of weights of the Radix Polygoni Multiflori, 50～55 unit of weights of Folium Mori, 38～42 unit of weights of Bulbus Fritillariae Cirrhosae, 30～35 unit of weights of Flos Magnoliae, 55～65 unit of weights of Herba Ecliptae, 28～35 unit of weights of Hippocampus, 25～35 unit of weights of Flos Carthami, 45～55 unit of weights of Semen sesami Niger, 38～45 unit of weights of Rhizoma Gastrodiae.

2, a kind of Chinese medicine for the treatment of alopecia is characterized in that it is the liquid preparation of being made through alcohol extraction by following materials of weight proportions: 45～50 unit of weights of Fructus Cnidii, 24～27 unit of weights of the Radix Stemonae, 9～11 unit of weights of Cortex Phellodendri, 24～26 unit of weights of Cacumen Platycladi, 1.8～2.2 unit of weights of ferrosisuifas crudus.