CN109432261A - Treat seborrhea, Chinese medicine composition of alopecia seborrheica and preparation method thereof - Google Patents

Treat seborrhea, Chinese medicine composition of alopecia seborrheica and preparation method thereof Download PDF

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CN109432261A
CN109432261A CN201811596729.4A CN201811596729A CN109432261A CN 109432261 A CN109432261 A CN 109432261A CN 201811596729 A CN201811596729 A CN 201811596729A CN 109432261 A CN109432261 A CN 109432261A
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seborrhea
chinese medicine
alopecia seborrheica
decoction
medicine composition
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徐丽
李大军
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    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
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Abstract

Seborrhea, Chinese medicine composition of alopecia seborrheica and preparation method thereof are treated the invention discloses a kind of, the traditional Chinese medicine ingredients of following parts by weight is used to be made: umbellate pore furgus 10g, Poria cocos 15g, raw Rhizoma Atractylodis Macrocephalae 15g, ramulus cinnamomi 10g, rhizoma alismatis 10g, black suitable piece 9g, Radix Salviae Miltiorrhizae 15g, psoralea corylifolia 10g, fruit of glossy privet 10g, eclipta 10g, mulberry leaf 10g, cacumen biotae 10g, rhizoma cyperi 10g, radix scutellariae 10g or licorice 6g.The formula of the invention is reasonable, prepares simply, rapid-action, significant in efficacy, Small side effects, recurrence rate after healing is low, there is significant curative effect to treatment seborrhea, alopecia seborrheica, kidney is good in anti-dandruff and itching-relieving, hair tonic, liver protection, achievees the purpose that treat seborrhea, alopecia seborrheica, and it has no toxic and side effect to human body, good absorption effect, cost is relatively low, and also tool can effectively improve body function.

Description

Treat seborrhea, Chinese medicine composition of alopecia seborrheica and preparation method thereof
Technical field
The present invention relates to Traditional chinese medicine medicament technical field, specially a kind of Chinese medicine for treating seborrhea, alopecia seborrheica Composition and preparation method thereof.
Background technique
Sebum be skin, lipid film sebaceous glands secretion, facilitate protect skin and with sweat Combined Protection Skin prevents drying.Sebum enables the skin to waterproof and works in the development of epidermal structure.It passes through acidification (cream The presence of acid and fatty acid) protect skin far from microorganism and to provide water resistance.It can make skin emolliency and in epidermis It works in growth.It is also found on chaeta and hair.
Seborrhea is made of the excessive production of the sebum by sebaceous glands.Seborrhea may have it is various at Cause: emotional stress, nervous, tired, the unbalance diet for deteriorating sebum secretion function, initiation reaction seborrhea Unfavorable cosmetics etc..Seborrhea also appears on scalp, and in the case where dandruff dermatitis, hair seems It is greasy and dull.It is cunning, moist in the case where serious seborrhea, and may be with rancid smell.
Most important in the reason of alopecia seborrheica is male pattern baldness, male can have found the hair of oneself top or frons Gradually become sparse, usual male pattern alopecia patient is often accompanied by scalp seborrhea, head while hair occurs and falling off too early Situations such as scurf is more, scalp pruritus.
Treatment seborrhea is commonly used at this stage, alopecia seborrheica mostly uses the mode of point massage and surgical operation to carry out Treatment, but therapeutic effect is bad, and treatment time is longer, is easy to make one to generate boredom, be unfavorable for treatment it is smooth into Row.According to theory of traditional Chinese medical science, hair and liver kidney have a substantial connection, the main blood of kidney storing essence liver, Hua Fa, liver kidney deficiency then asthenia of essence and blood, Hair follicle cannot get sufficient nutrition, and a kind of situation is synthesis of melanin reduced capability, white hair occurs, then there are also a kind of situations just It is hair follicle atrophy or necrosis, causes alopecia.Chinese traditional treatment can improve immunity of human body itself during the entire course for the treatment of, play The effect of one comprehensively regulating.It is safer and since Chinese medicine treatment side effect is small, receive the generally approval of patient.Cause This, a kind of Chinese medicine composition for treating seborrhea, alopecia seborrheica can be researched and developed by being badly in need of one kind.
Summary of the invention
In order to solve the above technical problems, the present invention provides and a kind of treats seborrhea, the Chinese traditional medicine composition of alopecia seborrheica Object and preparation method thereof, the Chinese medicine composition have the advantages that quick, therapeutic effect is good, it is without side-effects, do not rebound.
A kind of Chinese medicine composition for treating seborrhea, alopecia seborrheica, using the traditional Chinese medicine ingredients system of following parts by weight At: umbellate pore furgus 10g, Poria cocos 15g, raw Rhizoma Atractylodis Macrocephalae 15g, ramulus cinnamomi 10g, rhizoma alismatis 10g, black suitable piece 9g, Radix Salviae Miltiorrhizae 15g, psoralea corylifolia 10g, glossy privet Sub- 10g, eclipta 10g, mulberry leaf 10g, cacumen biotae 10g, rhizoma cyperi 10g, radix scutellariae 10g or licorice 6g.
The pharmacological action of Chinese medicine of the present invention is as follows:
Umbellate pore furgus: it is sweet in flavor, light, it puts down.Return heart, spleen, stomach, lung, kidney channel.Clearing damp and promoting diuresis.Control difficult urination, oedema, diarrhea, leaching It is turbid, leukorrhagia.
Poria cocos: it is sweet in flavor, light, it is mild-natured.Return heart, lung, spleen, kidney channel.Clearing damp and promoting diuresis, invigorating the spleen, calming heart.For edema and little urine, phlegm Drink feel dizzy and heart palpitations, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.
Raw Rhizoma Atractylodis Macrocephalae: returns spleen, stomach meridian, it is bitter, sweet and warm-natured.Function strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.
Ramulus cinnamomi: it is acrid flavour, sweet, it is warm-natured.Return lung, the heart, bladder meridian.Inducing sweat and dispelling exogenous evils, eliminating cold to stop pain, activating YANG and prormoting functioning of QI.For chill Flu, all pains of congealing cold with blood stasis, phlegm retention, blood stagnation syndrome, palpitaition.
Rhizoma alismatis: it is sweet in flavor, it trembles with fear.Enter kidney, bladder meridian.Li Shui, excreting dampness expel the heat-evil.Difficult urination, edema swelling are controlled, vomiting is rushed down Dysentery, phlegm retention, tinea pedis, stranguria syndrome, hematuria.
Black suitable piece: pungent, sweet, big heat；It is toxic.It belongs to the heart, kidney, spleen channel.Recuperating depleted yang, mends fire supporing yang, by wind-cold damp pathogen.For Yang depletion collapse, cold weak pulse of limb, impotence, palace cold, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold sensation of the genitalia oedema, deficiency of yang diseases caused by external factors, numbness and ache of cold dampness.
Radix Salviae Miltiorrhizae: bitter, it is slightly cold.Converge to heart and liver channels.Promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness and restlessness, cool blood to disappear carbuncle.For thoracic obstruction Pained, stomach duct and abdomen hypochondriac pain, a lump in the abdomen causing distension and pain, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhea menostasis, sore swell and ache curative.
Psoralea corylifolia: bitter, pungent, warm.Return kidney, the spleen channel.Tonifying kidney and strengthening yang, retention of essence and urine, kidney deficiency and lumbago, frequent urination, children lose Urine, kidney leakage, warming spleen and stopping diarrha, gas of receiving is relievingd asthma.For treating impotence due to deficiency of the kidney, soreness and weakness of waist and knees crymodynia, emission due to the kidney deficiency, the enuresis, frequent micturition etc.. For treating Diarrhoea caused by the insufficiency of both the spleen and the kindey.The cold of insufficiency type for treating the failure of the kidney in receiving air is breathed with cough.
The fruit of glossy privet: bitter sweet is put down.Enter liver, lung, kidney three to pass through.Nourishing liver and kidney, strong waist and knee.Yin asthenia generating intrinsic heat is controlled, dizzy, mesh flower, ear Ring, soreness and weakness of waist and knees, poliosis.It is nourishing liver and kidney, improving eyesight black hair.For dizziness and tinnitus, soreness and weakness of waist and knees, poliosis, mesh are secretly not It is bright.
Eclipta: it is sweet in flavor, sour, it is cold in nature.Return kidney, Liver Channel.It is nourishing liver and kidney, cooling blood and hemostasis.For the deficiency of liver-yin and kidney-yin, tooth pine It is dynamic, poliosis, dizziness and tinnitus, soreness and weakness of waist and knees, YinXuXueRe, haematemesis, bleeding from five sense organs or subcutaneous tissue, hematuria, bloody flux, metrostaxis, traumatic hemorrhage.
Mulberry leaf: bitter, sweet, cold nature.Return lung, Liver Channel.Pulvis refrigerans drop.Dispelling wind and heat from the body: swollen for anemopyretic cold and hot eyes Bitterly, often match chrysanthemum.It clears liver and improve vision: for wind fire eye disease (such as acute conjunctivitis).With Semen sesami nigrum name mulberry hemp pill, not for liver-yin It is sufficient, dizziness, blurring of vision caused by liver-yang hyperactivity.Clearing away the lungheat and moisturizing: it is used for lung-heat type cough: this product bitter cold eliminating heat from the lung, Gan Hanyi Yin, cool moistening lung dryness, therefore can be used for dry-heat impairing lung, dry cough lacks phlegm, less serious case can equally use with almond, the root of straight ladybell, fritillaria, such as sangxing decoction； Severe one can equally be used with gypsum, Radix Ophiopogonis, donkey-hide gelatin.
Cacumen biotae: it is bitter, puckery, it trembles with fear.Return lung, liver, the spleen channel.Cooling blood and hemostasis, preventing phlegm from forming and stopping coughing, growing and blacking hair.For spitting blood, it is defeated in battle Blood, hemoptysis, hematochezia, metrostaxis, cough with lung heat, blood-head alopecia, poliosis.
Rhizoma cyperi: pungent, slight bitter, micro- sweet and neutral.Return liver, spleen, tri-jiao channel.Soothing liver-qi stagnation, regulating the flow of QI to ease the stomach, menstruction regulating and pain relieving.For liver The strongly fragrant stagnation of the circulation of vital energy, distending pain in the chest and hypochondrium, hernia pain, swollen breasts, the taste stagnation of the circulation of vital energy, stomach duct and abdomen ruffian is bored, turgor pain, irregular menstruation, menostasis pain Through.
Radix scutellariae: nature and flavor: it is bitter, it trembles with fear.Enter the heart, lung, gallbladder, large intestine channel.Excess fire is rushed down, except damp and hot, hemostasis, miscarriage prevention.High fever polydipsia is controlled, Cough with lung heat, damp-heat dysentery, jaundice, heat gonorrhea are spat, are defeated in battle, collapse, are leaked, red eye, swell pain, threatened abortion, carbuncle swells furunculosis.
Licorice: sweet and neutral.Enter spleen, stomach, lung channel.Invigorating middle warmer and replenishing QI；Relieving spasm to stop pain；Moistening lung to arrest cough；Purging fire for removing toxin；It reconciles all Medicine.Main burnout deficiency of food；Emaciation with sallow complexion；Shortness of breath and palpitation；Abdominal pain loose stool；Four limbs contraction；Hysteria；Cough and asthma；Abscess of throat； Ulcerative carbuncle swelling and pain；Infant fetal toxin；And drug, food poisoning.
Another purpose according to the present invention provides and above-mentioned a kind of treats seborrhea, the Chinese medicine group of alopecia seborrheica The preparation method for closing object, includes the following steps:
S1 impregnates
With clean cold water by above-mentioned medicinal material unrestrained bubble 30-40 minutes, amount of water is advisable with not crossing medicinal material 1-2 centimeters, is allowed to It is impregnated with completely；
S2 is decocted
It uses mild fire after boiled with high heat instead, keeps slightly boiled, filter out decoction after decocting 20-30 minutes；It is added again appropriate Water filters out decoction with being cooked by slow fire 15-20 minutes after boiling；The decoction filtered out twice is merged into obtain oral decoction.
Further, it should be stirred often in decoction process, it is sufficiently fried with sharp effective component.
It is above-mentioned it is a kind of treat seborrhea, alopecia seborrheica Chinese medicine composition instructions of taking: point sooner or later eat twice Half an hour after warmly takes, one dose per day, every dose of decocting 400ml.
The beneficial effects of the present invention are:
A kind of Chinese medicine composition for treating seborrhea, alopecia seborrheica of the present invention, formula rationally, are prepared simply, are risen Effect is fast, and significant in efficacy, Small side effects, recurrence rate after healing is low, has significant curative effect to treatment seborrhea, alopecia seborrheica, goes Consider antipruritic, hair tonic to be worth doing, kidney is good in liver protection, achievees the purpose that treat seborrhea, alopecia seborrheica, and have no toxic and side effect to human body, Good absorption effect, cost is relatively low, and also tool can effectively improve body function.
Specific embodiment
Below in conjunction with the specific embodiment of the invention, technical solution of the present invention is clearly and completely described, is shown So, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based on the reality in the present invention Example is applied, every other embodiment obtained by those of ordinary skill in the art without making creative efforts all belongs to In the scope of protection of the invention.
Embodiment 1
A kind of Chinese medicine composition for treating seborrhea, alopecia seborrheica, using the traditional Chinese medicine ingredients system of following parts by weight At: umbellate pore furgus 10g, Poria cocos 15g, it is born from art 15g, ramulus cinnamomi 10g, rhizoma alismatis 10g, black suitable piece 9g, Radix Salviae Miltiorrhizae 15g, psoralea corylifolia 10g, glossy privet Sub- 10g, eclipta 10g, mulberry leaf 10g, cacumen biotae 10g, rhizoma cyperi 10g, radix scutellariae 10g or licorice 6g.
It is above-mentioned it is a kind of treat seborrhea, alopecia seborrheica Chinese medicine composition preparation method, include the following steps:
S1 impregnates
With clean cold water by above-mentioned medicinal material unrestrained bubble 30-40 minutes, amount of water is advisable with not crossing medicinal material 1-2 centimeters, is allowed to It is impregnated with completely；
S2 is decocted
It uses mild fire after boiled with high heat instead, keeps slightly boiled, filter out decoction after decocting 20-30 minutes；It is added again appropriate Water filters out decoction with being cooked by slow fire 15-20 minutes after boiling；The decoction filtered out twice is merged into obtain oral decoction.It decocted Cheng Zhongying is stirred often, sufficiently fried with sharp effective component.
Embodiment 2
Application method: a point morning and evening, postprandial half an hour warmly took twice, one dose per day, every dose of decocting 400ml.
Embodiment 3
Clinical data
Seborrhea, alopecia seborrheica patient 260 are observed and recorded from clinical practice, using Chinese medicine group of the invention It closes object to be treated, be taken after decocting, one dose per day, a point morning and evening, postprandial half an hour warmly took twice.10 days as one therapeutic course is treated altogether Two courses for the treatment of, wherein recovery from illness 206, effective 34, invalid 20, total effective rate 92.3%
It can be seen that having significant curative effect to treatment seborrhea, alopecia seborrheica using the present invention, there is anti-dandruff stop Itch, the effect of hair tonic, achievees the purpose that treat seborrhea, alopecia seborrheica, and have no toxic and side effect to human body, assimilation effect Good, cost is relatively low, and also tool can effectively improve body function.
Embodiment 4
Toxicity test:
1, acute toxicity test:
(1) mouse 40 are chosen, half male and half female, 25~34g of weight carries out acute toxicity test.Mouse is randomly divided into two Group, i.e. experimental group and control group, fasting 12 hours before testing；
(2) Chinese medicine composition of the invention is decocted into decoction, be dissolved in 10ml water, it is spare；
(3) take with step (2) same amount of normal saline, it is spare；
(4) take the traditional Chinese herbal decoction solution of the present invention in step (2) by the perfusion amount that stomach-filling volume is 5ml/kg to experimental group 20 mouse carry out perfusion；It is administered 2 times within one day, delivery time 6 hours, is observed continuously after administration 14 days, and record small The toxic reaction and death toll of mouse；
(5) 20 by the perfusion amount that stomach-filling volume is 5ml/kg to control group of same amount of normal saline in step (3) are taken Mouse carries out perfusion；It is administered 2 times within one day, delivery time 6 hours, is observed continuously after administration 14 days, and record the poison of mouse Property reaction and death toll；
The results showed that compared with the control group, mouse has no notable difference after experimental group administration, experiment is observed continuously 14 It, mouse systemic situation, diet, drinking-water, body weight increase are normal.
2, long term toxicity test:
Mouse 40 are chosen, half male and half female, 25~34g of weight carries out long term toxicity test.By traditional Chinese herbal decoction of the invention It is dissolved in 10ml water, perfusion, 2 times a day, continuous use 15 weeks is carried out to mouse by the perfusion amount that stomach-filling volume is 5ml/kg It is discontinued 3 weeks afterwards, carries out Germicidal efficacy.
The results showed that traditional Chinese herbal decoction of the present invention is to the hair of mouse, behavior, stool and urine, weight, organ weights, blood As, indexs such as hepatic and renal function, blood glucose, blood lipid all have no significant effect, internal organs naked eyes are without finding abnormal variation, histological examination knot Fruit shows that also nothing is substantially change Organs of Mice；Illustrate that Chinese materia medica preparation of the present invention to small toxicity after mouse long-term administration, is discontinued Afterwards also without abnormal reaction, application is safe.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And modification, the scope of the present invention is defined by the appended.

Claims (3)

1. a kind of Chinese medicine composition for treating seborrhea, alopecia seborrheica, which is characterized in that using in following parts by weight Medicine ingredient is made: umbellate pore furgus 10g, Poria cocos 15g, raw Rhizoma Atractylodis Macrocephalae 15g, ramulus cinnamomi 10g, rhizoma alismatis 10g, black suitable piece 9g, Radix Salviae Miltiorrhizae 15g, psoralea corylifolia 10g, fruit of glossy privet 10g, eclipta 10g, mulberry leaf 10g, cacumen biotae 10g, rhizoma cyperi 10g, radix scutellariae 10g or licorice 6g.
2. it is according to claim 1 it is a kind of treat seborrhea, alopecia seborrheica Chinese medicine composition preparation method, It is characterized by comprising the following steps:
S1 impregnates
With clean cold water by above-mentioned medicinal material unrestrained bubble 30-40 minutes, amount of water is advisable with not crossing medicinal material 1-2 centimeters, is allowed to complete It is impregnated with；
S2 is decocted
It uses mild fire after boiled with high heat instead, keeps slightly boiled, filter out decoction after decocting 20-30 minutes；Suitable quantity of water is added again, boils With being cooked by slow fire 15-20 minutes after boiling, decoction is filtered out；The decoction filtered out twice is merged into obtain oral decoction.
3. it is according to claim 2 it is a kind of treat seborrhea, alopecia seborrheica Chinese medicine composition preparation method, It is characterized in that, should be stirred often in decoction process, it is sufficiently fried with sharp effective component.
CN201811596729.4A 2018-12-26 2018-12-26 Treat seborrhea, Chinese medicine composition of alopecia seborrheica and preparation method thereof Pending CN109432261A (en)

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