CN109394806A - The processing method of ginseng radix polygonati officinalis - Google Patents
The processing method of ginseng radix polygonati officinalis Download PDFInfo
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- CN109394806A CN109394806A CN201710697857.7A CN201710697857A CN109394806A CN 109394806 A CN109394806 A CN 109394806A CN 201710697857 A CN201710697857 A CN 201710697857A CN 109394806 A CN109394806 A CN 109394806A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The present invention provides a kind of concocting methods of the dry property of ginseng in reduction ginseng radix polygonati officinalis product, specifically, including the following steps: a) to weigh ginseng, radix polygonati officinalis, cape jasmine by weight ratio；B) ginseng section with pure water infiltration it is saturating after be cut into ginseng piece it is spare；C) cape jasmine is taken, is crushed, extracting in water takes extracting solution to be centrifuged, and is concentrated；D) radix polygonati officinalis is taken, extracting in water takes extracting solution to be centrifuged, concentration；E) concentrate for mixing cape jasmine, radix polygonati officinalis, is added the ginseng piece prepared in step b), impregnates；F) take out soaked ginseng piece, drying to get.According in the compatibility of medicines in a prescription, Chinese medicine preparation, " with cold heating ", theoretical concocting method processes the present invention, and processed product color, mouthfeel are excellent, and can restrict " excessive internal heat " performance of long term usage ginseng appearance, provides a kind of new selection to clinical use ginseng piece.
Description
Technical field
The present invention relates to a kind of concocting methods for reducing the dry property of ginseng, specifically, being related to a kind of processing side of ginseng radix polygonati officinalis
Method.
Background technique
Ginseng is the root of Araliaceae ginseng Panax ginseng C.A.Mey., has and history and excellent is used for a long time
Effect, the medicinal of ginseng can be traced to before 2000, and cultivation history also had more than 1600 years away from the present.In the earliest materia medica in China
Have the record of ginseng on monograph Shennong's Herbal, be classified as top grade, it is believed that ginseng is sweet in flavor slightly cold, main tonifying five zang organs, peace essence
Mind, determine soul, stop palpitate with fear, remove pathogenic factor, improving eyesight, happy intelligence development, long term usage are made light of one's life by commiting suicide macrobiosis.Modern medicine also turns out that ginseng is in addition to energy
Outside nourishing and fit keeping function, in preventing tumor, anti-aging, anti-arrhythmia, inhibit Apoptosis, hypoglycemic, improvement learning and memory, enhancing
It sexual function and immune function and relieves the effect of alcohol etc. effective in cure.The main component for including in ginseng have ginsenoside, panaxan,
Panaxynol, volatile oil, low molecular peptide, amino acid, vitamin, organic acid and various trace elements.
Though ginseng is nutritious good tonic, lead to serious consequence, clinical manifestation if taking improper or dosage and crossing big city
For blood pressure raising, nosebleed, spiritual fever, dysphoria, insomnia, emotional, oversensitive, dizziness and headache, roserash,
The symptoms such as itch, body temperature raising, morning diarrhea, twitch, palpitation with fear and children's sex premature, are medically referred to as " Ginseng Poisoning syndrome ",
Also referred to as " ginseng abuse syndrome ".Chinese medicine think to take the adverse reaction after ginseng be because ginseng has the property of temperate-dryness, may
It will lead to that body mechanism of qi plug is stagnant, the trouble of dynamic blood generated, to limit the application of ginseng.
Currently, about reduce the dry property of ginseng concocting method still have the defects that it is certain, such as: number of patent application are as follows:
201310608362.4 (a kind of concocting methods of low dry property ginseng) process the color of gained ginseng, mouthfeel is not suitable for clinic
It uses.The reduction dry property of ginseng should reach improvement Jinseng health-care and drink " excessive internal heat " phenomenon often occurred.
Summary of the invention
To solve the above problems, the present invention provides a kind of concocting methods of the dry property of ginseng in reduction ginseng radix polygonati officinalis product.
The present invention provides a kind of concocting methods of the dry property of ginseng in reduction ginseng radix polygonati officinalis product: it includes the following steps:
A, by weight it is 1:(0.1~1): (0.1~1), which weighs, takes ginseng, radix polygonati officinalis, cape jasmine；
B, ginseng section with pure water infiltration it is saturating after be cut into ginseng piece it is spare；
C, cape jasmine is taken, is crushed, adds 5-12 times of water to extract, extracting solution is taken to be centrifuged, is concentrated；
D, radix polygonati officinalis is taken, adds 5-12 times of water to extract, extracting solution is taken to be centrifuged, is concentrated；
E, the concentrate of cape jasmine, radix polygonati officinalis is mixed, the ginseng piece prepared in step b is added, is impregnated；
F, take out soaked ginseng piece, drying to get.
Wherein, in step a, ginseng, radix polygonati officinalis, cape jasmine weight ratio be 1:0.25:0.8；It is described and/or in step b
Join piece with a thickness of 0.1~4mm, it is preferable that ginseng piece is with a thickness of 3mm.
Wherein, in step c, cape jasmine is crushed to 40 mesh, and 12 times of water is added to extract 3 times, and Extracting temperature is 45-90 DEG C, preferably warm
Degree is 50-55 DEG C, and optimally, temperature is 55 DEG C；Extraction time is 1-2h, it is preferable that extraction time 1h.
Wherein, in step c, the concentration is to be concentrated under reduced pressure, and it is 50-70 DEG C that temperature, which is concentrated under reduced pressure,；Preferably, temperature is
55℃。
Wherein, in step c, enriched standard is 2.5-3 times of volume for being concentrated into cape jasmine dry weight；Preferably, it is concentrated into cape jasmine
3 times of volumes of dry weight.
Wherein, in step d, radix polygonati officinalis with 10 times water 2 times, Extracting temperature be 90 DEG C.
Wherein, in step d, the concentration is to be concentrated under reduced pressure, 60-70 DEG C of thickening temperature, it is preferable that thickening temperature 63
℃。
Wherein, in step d, enriched standard is 2.5-3 times of volume for being concentrated into radix polygonati officinalis dry weight；Preferably, it is concentrated into radix polygonati officinalis
3 times of volumes of dry weight.
Wherein, in step e, soaking conditions are as follows: soaking temperature is 25 DEG C -100 DEG C, and preferably soaking temperature is 85 DEG C, is impregnated
Time is 10-30min, it is preferable that soaking time 15min.
Wherein, in step f, the drying condition is 60 DEG C of hot-air seasonings；Drying standard is to be dried to water content 10%
Below.
Concocting method of the present invention is theoretical according to " being heated in the compatibility of medicines in a prescription, Chinese medicine preparation with cold ", is extracted using cape jasmine, radix polygonati officinalis
Liquid processes ginseng, cape jasmine clearing heat-fire, and radix polygonati officinalis nourishing yin to moisten dryness matches with ginseng, can retain ginseng QI invigorating, the function of nourishing,
" excessive internal heat " performance of long term usage ginseng appearance can be restricted again, and processed product color, mouthfeel are excellent, provide one to clinical use ginseng piece
The new selection of kind.
Obviously, above content according to the present invention is not being departed from according to the ordinary technical knowledge and customary means of this field
Under the premise of the above-mentioned basic fundamental thought of the present invention, the modification, replacement or change of other diversified forms can also be made.
The specific embodiment of form by the following examples remakes further specifically above content of the invention
It is bright.But the range that this should not be interpreted as to the above-mentioned theme of the present invention is only limitted to example below.It is all to be based on above content of the present invention
The technology realized all belongs to the scope of the present invention.
Detailed description of the invention
Processed product of the present invention under the Extracting temperature of Fig. 1 difference cape jasmine
Specific embodiment
The processing method of the present invention of embodiment 1
1, ginseng 100g, radix polygonati officinalis 25g, cape jasmine 80g are taken.
2, ginseng section moisturizes rear cut into serving pieces, piece thickness 3mm with pure water.
3, cape jasmine is made, concentrate is extracted in the mixing of radix polygonati officinalis.
Cape jasmine is crushed to 40 mesh, and 12 times of water are added and extract 3 times, 55 DEG C of Extracting temperature, extracts 1.5h, extracting solution is taken to be centrifuged,
It is concentrated under reduced pressure, 55 DEG C of thickening temperature, is concentrated into 3 times of volumes of cape jasmine dry weight.
Radix polygonati officinalis is extracted 2 times, each 60min with 10 times 90 DEG C of water, and combined extract is concentrated under reduced pressure, thickening temperature after centrifugation
63 DEG C, it is concentrated into 3 times of volumes of radix polygonati officinalis dry weight.
4, the concentrate of cape jasmine, radix polygonati officinalis is heated after mixing, 85 DEG C of heating is simultaneously kept, and is blended into ginseng piece, is impregnated
20min filters out ginseng piece.
5, will ginseng piece with 60 DEG C of hot-air seasonings to 10% or less water content to obtain the final product.
The processing method of the present invention of embodiment 2
1, ginseng 100g, radix polygonati officinalis 35g, cape jasmine 100g are taken.
2, ginseng section moisturizes rear cut into serving pieces, piece thickness 0.1mm with pure water.
3, cape jasmine is made, concentrate is extracted in the mixing of radix polygonati officinalis.
Cape jasmine is crushed to 40 mesh, and 12 times of water are added and extract 3 times, and Extracting temperature is 50 DEG C, extracts 1h, depressurizes after centrifugation dense
Contracting, temperature 70 C are concentrated into 3 times of volumes of cape jasmine dry weight.
Radix polygonati officinalis is extracted twice with 10 times 90 DEG C of water, and combined extract is concentrated under reduced pressure after centrifugation, and 65 DEG C of thickening temperature, concentration
To 3 times of volumes of radix polygonati officinalis dry weight.
4, the concentrate of cape jasmine, radix polygonati officinalis is heated after mixing, is heated to slightly boiled and keeps, be blended into ginseng piece, sufficiently soaked
15min is steeped, ginseng piece is filtered out.
5, will ginseng piece with 60 DEG C of hot-air seasonings to 10% or less water content to obtain the final product.
The processing method of the present invention of embodiment 3
1, ginseng 100g, radix polygonati officinalis 50g, cape jasmine 50g are taken.
2, ginseng section moisturizes rear cut into serving pieces, piece thickness 4mm with pure water.
3, cape jasmine is made, concentrate is extracted in the mixing of radix polygonati officinalis.
Cape jasmine is crushed to 40 mesh, and 12 times of water are added and extract 3 times, 90 DEG C of Extracting temperature, extracts 1h, is concentrated under reduced pressure after centrifugation,
Temperature 70 C is concentrated into 2.5 times of volumes of cape jasmine dry weight.
Radix polygonati officinalis is extracted twice with 10 times 90 DEG C of water, and combined extract is concentrated under reduced pressure after centrifugation, and 70 DEG C of thickening temperature, concentration
To 3 times of volumes of radix polygonati officinalis dry weight.
4, the concentrate of cape jasmine, radix polygonati officinalis is heated after mixing, is heated to slightly boiled and keeps, be blended into ginseng piece, sufficiently soaked
30min is steeped, ginseng piece is filtered out.
5, will ginseng piece with 60 DEG C of hot-air seasonings to 10% or less water content to obtain the final product.
The parameter selection of the processing method of the present invention of embodiment 4
The selection of 1 cape jasmine Extracting temperature
The extraction concentrate of experiment discovery cape jasmine is the key factor for influencing dry plate color and brewing rear soup look, Extracting temperature
It increases, extracting solution color is dim, smell is dull, mouthfeel is bitter, corresponding dry plate color and brews rear soup look and deepens, is dimmed, extracts
Temperature reduces, and extracting solution color is vivid, smell is salubrious, mouthfeel is not bitter, corresponding dry plate color and brews rear soup look and shoals, becomes
It is bright.
Remaining technique remains unchanged, and the Extracting temperature of cape jasmine is respectively: 48-56 DEG C, 57-65 DEG C, 66-74 DEG C, 75-83 DEG C
When, process the result is shown in Figure 1.According to result it can be seen that 48-56 DEG C of group color is pale yellow, Shang Mingliang；The bright Huang of 57-65 DEG C of group color is general
Red and red uniformly implicit glossy, 66-74 DEG C of group is dark yellow general brown, 75-83 DEG C of group chocolate.
It further selects 48-65 DEG C of temperature to optimize, 50 DEG C, 55 DEG C, 60 DEG C, 65 DEG C；Numerical representation method: 3=is good, 2=
Generally, 1=is bad, and the selection result is shown in Table 1.
By the selection result it is found that cape jasmine is in the case where 55 DEG C of temperature are as extraction conditions, ginseng tablet of the present invention has good color
Pool and mouthfeel.
The selection of 2 radix polygonati officinalis Extracting temperatures
Under different Extracting temperatures, color, smell, mouthfeel can change radix polygonati officinalis.Other parameters condition is constant, changes radix polygonati officinalis
Extracting temperature, the smell difference of radix polygonati officinalis extracting solution extracted at a temperature of investigating 70 DEG C, 80 DEG C, 90 DEG C is unobvious, and color is with temperature
It spends to increase and slightly deepen, and mouthfeel flavour becomes weight, but to the color in blocks of ginseng piece, the color influence of soup is unobvious, and analysis is
It is more stable to temperature since radix polygonati officinalis effective component is mainly fragrant solomonseal rhizome polyoses, and ratio of the radix polygonati officinalis in ginseng piece processing is lower, shadow
It rings less, preferably takes most apparent 90 DEG C of mouthfeel flavour to do Extracting temperature.
3 infiltration process choices
Immersion will affect ginseng piece character, total Ginsenosides Content, brew soup look mouthfeel, need to strictly be sieved to soaking technology
Choosing.
3.1 ginseng piece total Ginsenosides Content detection method explanations
3.1.1 ginseng content detection is carried out with reference to 2015 editions " pharmacopeia " Cape jasmine system ginseng pieces, processing drying ginseng piece.
3.1.2 experimental program: chromatographic condition and system suitability
Using octadecylsilane chemically bonded silica as filler；Using acetonitrile as mobile phase A, using water as Mobile phase B, according to the form below
Regulation carry out gradient elution；Detection wavelength is 203nm.Number of theoretical plate presses ginsenoside Rg1Peak, which calculates, should be not less than 6000.
Precision weighs ginsenoside Rg respectively for the preparation of reference substance solution1Reference substance, ginsenoside Re's reference substance and ginseng
Saponin(e Rb1Reference substance adds methanol that every lml is made respectively containing the mixed solution of 0.2mg, shake up to get.
The preparation of solid test solution takes this product powder (crossing No. four sieves) about lg, accurately weighed, sets in Soxhlet extractor,
Add chloroform to be heated to reflux 3 hours, discard chloroform liquid, the dregs of a decoction volatilize solvent, move into 100ml conical flask together with filtration paper cylinder
In, precision plus water-saturated n-butanol 50ml, close plug are stood overnight, ultrasonic treatment (power 250W, frequency 50kHz) 30 minutes, filter
It crosses, discards primary filtrate, precision measures subsequent filtrate 25ml, sets in evaporating dish and be evaporated, residue adds methanol to dissolve and is transferred to 5ml measuring bottle
In, add methanol dilution to shake up to scale, filter, take subsequent filtrate to get.
3.1.3 experimental material
3.1.4 instrument: high performance liquid chromatograph, electronic balance, water-bath, Ultrasound Instrument, Soxhlet extractor, conical flask, cold
Solidifying pipe, volumetric flask, solvent filter, water system filter membrane, organic filter, syringe, sample injection bottle, evaporating dish, pipette
3.1.5 reagent: methanol, acetonitrile, chloroform, ether n-butanol, water-saturated n-butanol solution, reference substance solution.
3.2 finished products join piece brewing liquid spectrophotometry clarity:
3.2.1 instrument: spectrophotometer (precision ± 0.5T%).
3.2.2 detection method: weighing sample 10g, be accurate to 0.1g, be dissolved in water and be settled to 100ml, shake up, as
Test solution.It is washed and is injected in 10mm cuvette with test solution, with same batch of water conditioning instrumentation zero point of sample dissolution, at Yu Bochang 430nm,
Measure its light transmittance.Measurement result is accurately to integer.Tolerance: same sample measures twice, and the difference of absolute value must not exceed 1%
3.3 investigation different technical parameters join tablet quality to finished product and brew the influence of soup look mouthfeel, have mainly investigated infiltration
The heating temperature of liquid, heating method, infiltrating time length.
3.3.1 there are two types of heating methods:
1 immersion fluid adds the infiltration of trepang piece after being heated to technological temperature；After 2 at room temperature arrive trepang piece addition immersion fluid
It is heated to technological temperature.
Join the total Ginsenosides Content comparison of piece under different heating mode:
As can be seen that first heating immersion fluid adds the mode of ginseng piece, it can operatively retain containing for general ginsenoside
Amount.
3.3.2 heating temperature: room temperature (25 DEG C), 40 DEG C, 55 DEG C, 70 DEG C, 85 DEG C, 100 DEG C.(infiltration 40 minutes)
Known to experimental result: the transparency of infiltration temperature soup at 70 DEG C or more is good, joins piece color when temperature is higher,
Soup coloration deepen it is obvious, while total content of ginsenoside variation tendency of finished product ginseng piece be reduce, therefore select 85 DEG C as
Technique heating temperature.
3.3.3 the investigation of infiltrating time length: 10 minutes, 20 minutes, 30 minutes, 40 minutes, 50 minutes, 60 minutes.(85
℃)
Known to experimental result: the transparency of infiltrating time soup in each duration is all good, joins piece color when the time is longer
It is gradient to yellowish-brown from yellow, soup coloration is deepened obviously, is gradient to dark yellow band orange from golden yellow, while joining the total of piece in flakes
It is reduction that content of ginsenoside, which lengthens variation tendency with infiltrating time, therefore 20 minutes a length of when selection infiltration.
The sense organ comparative study of experimental example 1 present invention and other ginseng products
It chooses 2 kinds of ginseng products and does sense organ comparison with the ginseng radix polygonati officinalis that this technique is processed into, select 6 kinds of evaluations to refer to altogether
Mark, is respectively as follows: color, the uniform degree of dry plate；Soup look, clarity, mouthfeel flavour, resistance to bubble degree after brewing.The mode brewed
It is that ginseng piece and drinking water ratio 1:50, boiling water brew, infusion liquid is filtered out after 1 minute, observation is tasted, scoring, each index
Full marks are 10 points.
The present invention joins piece: being made according to 1 concocting method of embodiment.
Ginseng tablet: it purchases from Sichuan NEAUTUS Traditional Chinese Medicine Co., Ltd., lot number: 1503014.
Low dry property ginseng: the patent application processing method that referenced patent application number is 201310608362.4 is made.
Known to experimental result: the present invention joins piece dry plate and is substantially better than low dry property ginseng tablet, and mouthfeel soup look is substantially better than common
Ginseng tablet.Indices after preparing the low dry property ginseng tablet's dry plate quality obtained in the prior art and brewing are not achieved original
Join the effect of piece.It is superior in quality that the present invention joins piece dry plate, brews that rear soup look is good, and mouthfeel flavour is excellent.
The influence of experimental example 2 present invention ginseng piece and common ginseng to rat oxygen demand
1 experimental material:
1.1 animals: SD rat totally 30,160-220 grams of weight, purchase tests Company of Animals Ltd. from Chengdu up to rich fruit.
1.2 Ginseng extracts:
Common Ginseng extract: it buys from Sichuan NEAUTUS Traditional Chinese Medicine Co., Ltd., lot number: 1503014；According to
The solid-to-liquid ratio extracting in boiling water of 1:10 1 hour is extracted twice, merges extracting solution twice, be concentrated under reduced pressure into solid-to-liquid ratio ginseng: concentrate
For 1:10.
The present invention joins piece extracting solution: processed product made from 1 concocting method of Example is mentioned according to the solid-to-liquid ratio boiling water of 1:10
It takes 1 hour, extracts twice, merge extracting solution twice, be concentrated under reduced pressure into solid-to-liquid ratio ginseng: concentrate is 1:10.
1.3 reagent
Soda lime
1.4 instrument
Wide-mouth bottle, pipette, beaker, rubber stopper, rubber tube, glass tube, spring clip, iron stand, gauze.
2 experiments
2.1 test groupings and administration
30 rats are randomly divided into 3 groups, respectively control group, ginseng group, invention group, use physiological saline, ginseng respectively
Concentrate, ginseng radix polygonati officinalis concentrate gastric infusion, according to 2.7ml/kg stomach-filling, 2 times/day, continuous 3 weeks.
The measurement of 2.2 oxygen demand
Rat is put into closed wide-mouth bottle, enough soda limes are put into wide-mouth bottle, rat oxygen intake breathes out dioxy
Change carbon, carbon dioxide can be absorbed by soda lime, and air pressure can reduce in wide-mouth bottle, be recorded by this principle from starting rats death
When buret pressure reduce height, as total oxygen demand of rat.
This test need to record total oxygen demand, time, rat body weight, and calculate the oxygen demand in the rat unit time, unit
Time oxygen demand calculation formula is as follows:
Unit time oxygen demand=total the oxygen demand of survival period (ml)/(time-to-live min × weight g) (unit: ml/min
g)
Test result is shown in Table 2:
Influence of the different ginseng pieces of table 2 to rat oxygen demand
| Group | Sample number | Oxygen demand (ml/ming) |
| Control group | 10 | 0.03195±0.00222 |
| Of the present invention group | 10 | 0.03231±0.01330 |
| Common ginseng group | 10 | 0.04005±0.01893* △ |
Note:*Indicate that there is significant difference, P < 0.05 compared with the control group
△Indicate that there is significant difference, P < 0.05 compared with ginseng radix polygonati officinalis group
According to the experimental results: ginseng group oxygen demand is significantly higher than control group and of the present invention group, of the present invention group of oxygen demand with
Control group is not significantly different.The obvious more common ginseng of ginseng piece that can be seen that the present invention makes can reduce rat and disappear to oxygen
Consumption has " drop is dry " effect.
3 present invention of experimental example and influence of the common ginseng to the daily amount of drinking water of rat unit weight
Experimental rat in experimental example 2 measures rat whole day amount of drinking water, and unit of account weight in last all day of third
Daily amount of drinking water.Calculation formula is as follows:
The daily amount of drinking water of per weight=daily drink total amount (ml)/weight (g) (unit: ml/g days)
Test result see the table below 3:
Influence of the different ginseng pieces of table 3 to the daily amount of drinking water of rat
| Group | Sample number | The daily amount of drinking water of per weight (ml/g days) |
| Control group | 10 | 0.10240±0.0145 |
| Of the present invention group | 10 | 0.14100±0.0293 |
| Common ginseng group | 10 | 0.11780±0.01416* △ |
Note: * indicates there is significant difference, P < 0.05 compared with the control group
△ indicates there is significant difference, P < 0.05 compared with ginseng radix polygonati officinalis group
According to the experimental results: the daily amount of drinking water of ginseng group per weight is significantly higher than control group and of the present invention group of (P <
0.05), the of the present invention group of daily amount of drinking water of per weight and control group are not significantly different (P > 0.05).The ginseng that the present invention makes
Piece, which can significantly improve, takes the performance such as common ginseng bring mouth parched and tongue scorched, excessive internal heat for a long time, has " drop is dry " effect.
4 present invention of experimental example and common ginseng piece long-term drinking assessment
1. personnel's selection standard of testing and assessing: choosing 20 normal adults, the age at 25-45 years old, is divided into two groups, every group 10
People.
2. ginseng group is drunk with the ginseng that boiling water brews the preparation of 6 grams of conventional methods daily, of the present invention group is rushed with boiling water daily
The ginseng piece for steeping the preparation of 6 grams of the method for the present invention is drunk, and is persistently drunk 7 days, is not during which taken in other drinks.8th day from whether dry
Tongue is dry, whether mycteroxerosis, whether eyes it is dry and astringent, whether body heat insomnia etc. 4 consciously performance is filled up a form.
According to the experimental results, ginseng piece obtained by concocting method of the present invention can be obviously improved in clinical application takes commonly
Join the symptoms such as mouth parched and tongue scorched, mycteroxerosis, dry and astringent, the hot insomnia of body of eyes that tablet tea occurs.It can be with concocting method of the invention
It is obviously improved the dry property of common ginseng piece.
In conclusion concocting method of the present invention is theoretical according to " being heated in the compatibility of medicines in a prescription, Chinese medicine preparation with cold ", using Cape jasmine
Son, radix polygonati officinalis extracting solution process ginseng, cape jasmine clearing heat-fire, radix polygonati officinalis nourishing yin to moisten dryness, with ginseng match, can retain ginseng QI invigorating,
The function of nourishing, and " excessive internal heat " performance of long term usage ginseng appearance can be restricted, processed product color, mouthfeel are excellent, give clinical use
Ginseng piece provides a kind of new selection.
Claims (10)
1. a kind of concocting method for reducing the dry property of ginseng in ginseng radix polygonati officinalis product, it is characterised in that: it includes the following steps:
A, by weight it is 1:(0.1~1): (0.1~1), which weighs, takes ginseng, radix polygonati officinalis, cape jasmine；
B, ginseng piece is cut into after ginseng is moisturized with water logging；
C, cape jasmine is taken, is crushed, adds 5-12 times of water to extract, extracting solution is taken to be centrifuged, is concentrated；
D, radix polygonati officinalis is taken, adds 5-12 times of water to extract, extracting solution is taken to be centrifuged, is concentrated；
E, the concentrate of cape jasmine, radix polygonati officinalis is mixed, the ginseng piece prepared in step b is added, is impregnated；
F, take out impregnate after ginseng piece, drying to get.
2. according to the method described in claim 1, it is characterized by: in step a, ginseng, radix polygonati officinalis, cape jasmine weight ratio be 1:
0.25:0.8；And/or in step b, the ginseng piece is with a thickness of 0.1~4mm, it is preferable that ginseng piece is with a thickness of 3mm.
3. according to the method described in claim 1, adding 12 times of water to extract 3 it is characterized by: cape jasmine is crushed to 40 mesh in step c
Secondary, Extracting temperature is 45-90 DEG C, and preferable temperature is 50-55 DEG C, and optimally, temperature is 55 DEG C；Extraction time is 1-2h, preferably
Ground, extraction time 1h.
4. according to the method described in claim 1, it is characterized by: the concentration is to be concentrated under reduced pressure, and decompression is dense in step c
Contracting temperature is 50-70 DEG C；Preferably, temperature is 55 DEG C.
5. according to the method described in claim 1, it is characterized by: enriched standard is to be concentrated into cape jasmine dry weight in step c
2.5-3 times of volume；Preferably, 3 times of volumes of cape jasmine dry weight are concentrated into.
6. according to the method described in claim 1, it is characterized by: in step d, radix polygonati officinalis with 10 times water 2 times, Extracting temperature 90
℃。
7. according to the method described in claim 1, it is characterized by: the concentration is to be concentrated under reduced pressure, and concentration is warm in step d
60-70 DEG C of degree, it is preferable that thickening temperature is 63 DEG C.
8. according to the method described in claim 1, it is characterized by: enriched standard is to be concentrated into radix polygonati officinalis dry weight in step d
2.5-3 times of volume；Preferably, 3 times of volumes of radix polygonati officinalis dry weight are concentrated into.
9. according to the method described in claim 1, it is characterized by: in step e, soaking conditions are as follows: soaking temperature is 25 DEG C-
100 DEG C, preferably soaking temperature is 85 DEG C, soaking time 10-30min, it is preferable that soaking time 15min.
10. according to the method described in claim 1, it is characterized by: the drying condition is that 60 DEG C of hot winds dry in step f
It is dry；Drying standard is to be dried to 10% or less water content.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110585254A (en) * | 2019-09-18 | 2019-12-20 | 让贤昌(天津)食品有限公司 | Preparation method of original ecological ginseng chewable tablets and granules |
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| CN103655652A (en) * | 2013-11-27 | 2014-03-26 | 辽宁中医药大学 | Processing method for low-dry ginseng |
| CN104147360A (en) * | 2014-08-27 | 2014-11-19 | 赵大庆 | Composition for eliminating dryness-heat property of ginseng and preparation method thereof |
| CN104189476A (en) * | 2014-09-25 | 2014-12-10 | 桓仁满族自治县益仁堂中药材有限公司 | Extract containing ginseng |
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| CN101332214A (en) * | 2008-08-01 | 2008-12-31 | 辽宁中医药大学 | Panax processing technique |
| CN102670682A (en) * | 2011-06-21 | 2012-09-19 | 张泽来 | Modified highest-grade tribute red ginseng and preparation method thereof |
| CN103655652A (en) * | 2013-11-27 | 2014-03-26 | 辽宁中医药大学 | Processing method for low-dry ginseng |
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| CN110585254A (en) * | 2019-09-18 | 2019-12-20 | 让贤昌(天津)食品有限公司 | Preparation method of original ecological ginseng chewable tablets and granules |
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