CN104147360A - Composition for eliminating dryness-heat property of ginseng and preparation method thereof - Google Patents
Composition for eliminating dryness-heat property of ginseng and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a composition for eliminating dryness-heat property of ginseng and a preparation method thereof and belongs to the field of traditional Chinese medicines. The method includes following steps: employing 0.5-5.5 parts of ginseng, 1-19 parts of polygonatum odoratum, 1-11 parts of lily and 0.5-9.5 parts of radix glycyrrhizae as raw materials; crushing the raw materials; mixing the raw materials; adding water with a volume amount being 6-10 times; performing a decocting process and a filtering process with a filtrate for later use; adding 5-95% ethanol, with a volume amount being 6-10 times, to a residue and performing reflux extraction for 2-3 times, wherein each reflux extraction lasts for 2-6 hours; mixing and filtering extracts to obtain a filtrate; recycling the ethanol from the filtrate and mixing the filtrate with a water decoction liquid; and performing a concentrating process continuously until an extract with a relative density being 1.03-1.08 is obtained. The invention is advantaged in that: with the guide of traditional Chinese medicine theories, a scientific combination of the ginseng with drug-diet cold and cool raw materials is carried out since the ginseng is warm and dry. A modern preparation method of traditional Chinese medicines is employed. A clinical experiment research result proves that the dryness-heat property of the ginseng is reduced by means of the composition prepared through the combination and preparation method. A gingseng "non-heating" product, prepared through the method, does not cause a heating symptom when being used for a long period and having a regulation effect on body functions of a subject at a certain degree. The composition has great market competiveness.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate in particular to Radix Ginseng except compositions and the method processed thereof of dry property.
Background technology
Radix Ginseng (
panax ginsengc.A.Mey.) be rare Chinese medicine, have " kings of hundred medicines " good reputation, < < gift latitude bucket impressive and dignified manner > >: " monarch take advantage of wood and king has the Radix Ginseng raw ".< < A Supplement to the Compendium of Materia Medica > >: " Radix Ginseng three fork five leaves, are the vital essence of reporting the three ability five elements, post shape in herbaceous stem, are the king of BAICAO ".> > on < < The book of Changes copulative: " vital essence is thing, and wandering ghost, for becoming, is old friend ghosts and gods' situation state." < < county annals > > near a river: " be born between the group's grass of remote mountains, be not subject to the bullying and humiliation of group's grass.As group's grass, drape over one's shoulders away from chi and permitted outward, it is high-spirited so, and independent central person, must be Radix Ginseng." Radix Ginseng be in the world range of application maximum, apply most populous Chinese crude drug.Present stage Radix Ginseng purposes in China's Chinese medicine is very extensive, and the number of times occurring in Chinese Pharmacopoeia and ministry standard all makes number one, and has in the world 89 countries and regions to sell Radix Ginseng or ginseng product.
The chemical composition that Radix Ginseng contains mainly comprises: Ginsenosides, organic acid and esters, protide, vitamins, sterol and glycoside thereof, in addition, also contain: Conversion of Adenosine enzyme, L-Aspartic acid enzyme, beta amylase, invertase; Maltol, nonacosane; 20 various trace elements such as nimbecetin, panasenoside and copper, zinc, ferrum, manganese.
Tradition ancient books is recorded Radix Ginseng, and " main tonifying five ZANG-organs, pacifies spirit, determines soul, and spasmolytic is throbbed with fear, and removes pathogen, improving eyesight, happy Fructus Alpiniae Oxyphyllae.Clothes, make light of one's life by commiting suicide and prolong life for a long time ".
Modern pharmacological research shows that Radix Ginseng has and regulates and protective effect cardiovascular system, central nervous system and liver, and can shock, also has the function etc. of removing free radical.
2012, ministry of Health of China official approval artificial growth Radix Ginseng was new resource food.Yet Radix Ginseng " dry property " problem becomes the biggest obstacle of China's Radix Ginseng extensive use.Whether Radix Ginseng has the property of warm-dryness syndrome, and namely the Radix Ginseng of eating of folklore " is got angry ", is the problem that domestic consumers in general query always.Jilin Province organizes a large amount of researchers without Radix Ginseng and the product of the time limit, to carry out toxicologic study to different cultivars, and a large amount of zoopery of result fails to provide clear and definite conclusion.
About Radix Ginseng " dry property " problem, domestic correlational study is summarized as follows.
" a kind of method for making of local flavor Radix Ginseng " of people's inventions such as Liu Li, that Radix Ginseng is by adding after natural fruit juice or organic acidic material reaction, reduce triol saponins component content, improve the method for rare saponin constituent content, in patent description, Ginseng Products has been carried out the detection of saponin, Ginseng Products has not been carried out to " dry property " and evaluate.
White " ' reducing internal heat ' Radix Ginseng of preparing based on biological catalysis " that waits people's invention of analogy spring, to adopt the method for spraying enzyme liquid after wet ginseng punching, improve low polarity saponin content in Radix Ginseng, in patent description, protopanoxadiol type saponin in product and Protopanaxatriol's type saponin are measured, Ginseng Products is not carried out to " dry property " and evaluate.
" a kind of active ginseng crisp and preparation method thereof " of people's inventions such as Zhao Baitao, fresh ginseng is made through sterilizing, cut into slices, soak the processes such as sugar, quick-freezing, vacuum lyophilization, packing, in patent description, product has been carried out to observation on Clinical Application analysis, mainly observed product to physical fatigue and mental fatigue effect, reaction to phenomenons such as xerostomia, dryness of the tongue, dry pharynxs, clinical effectiveness is that product has obvious effect to physical fatigue, mental fatigue, to having the crowd of the signs of getting angry such as xerostomia, dryness of the tongue, dry pharynx, is significantly improved.But the index of the Clinical observation of enumerating in patent description is few.
" a kind of food that contains Radix Ginseng " of people's inventions such as Fan Yuchang, by 34 taste raw materials, formed, make the food consumption such as medicated porridge, soup or preserve, in explanation, only sketch food and removed and balanced the scorching property of Radix Ginseng, making the present invention be applicable to everyone eats, also be applicable to hypertension, diabetes, asthma patient, child and teenager edible, detection method etc. is not described in detail in detail.
In addition, " a kind of prophylactic treatment cough and asthma pear, peach and apricot honey sugar slab " of people's inventions such as Li Yongsheng, " a kind of Chinese medicine preparation for the treatment of the esophageal carcinoma and preparation method thereof " of people's inventions such as Li Baoming, " a kind of life lengthening Chinese medicine product that is applicable to women and preparation method thereof " of Li Zude invention, " a kind of medicine for the treatment of pneumonopathy " of Wu Qingling invention, in " a kind of prophylactic treatment cough and asthma pear, peach and apricot honey sugar slab " of people's inventions such as Li Yongsheng, people is participated in to Bulbus Lilii, Rhizoma Polygonati Odorati, after the drug matchings such as Radix Glycyrrhizae, special role in some aspects also has report, but all do not relate to and in this patent, protect content.
Summary of the invention
The invention provides a kind of composition and method of making the same of removing the dry property of Radix Ginseng, while eating Radix Ginseng to solve, have the problem of dry property.
For this problem, the inventor organizes Traditional Chinese Medicine Experts to prove, and thinks: " getting angry " is the disease of the traditional Chinese medical science, and evaluation methodology should be clinical experiment, goes the effective way of dry property can pass through traditional Chinese medical science compatibility simultaneously.Therefore, the inventor is the article list > > of food and medicine from the < < of Ministry of Public Health in March, 2002 issue, according to the nature and flavor of Radix Ginseng, select tens kinds of medical materials to carry out compatibility, and the method research experiment that adopts human experiment and clinical evaluation to combine, test-meal crowd takes the crowd that dry property symptom appearred in Radix Ginseng single medical material, result shows, the Ginseng Products of compatibility under the present invention instructs, under existing test-meal number of cases, there is not " getting angry " symptom, by this method, removed the dry property of Radix Ginseng.
Principal agent Radix Ginseng sweet in the mouth, slightly warm in nature, the traditional Chinese medical science thinks that Radix Ginseng has strongly invigorating primordial QI, slakes thirst and help produce saliva, the effect of adjusting nutrition to defend.It is top grade that motherland's medical science is classified as health care, and be used as the traditional Chinese medical science " strengthening the body resistance " and west is referred to as the first-selection of " adapt to former state medicine ", and the energy Computer Associates International Inc. of QI invigorating is careless, enjoys the good reputation of " king of BAICAO ".
Modern study shows: Radix Ginseng all has significant pharmacological action to animal and human, and Radix Ginseng has enhancing body resistance, adjusts body function, promotes substance metabolism, regulates the effects such as nervus centralis and endocrine.
Rhizoma Polygonati Odorati sweet in the mouth, cold nature, does not hinder heresy though mend, and is the good medicine of YIN nourishing and the production of body fluid promoting.Rhizoma Polygonati Odorati nourishing YIN, Radix Ginseng YANG invigorating, negative and positive have help wonderful, and lid Radix Ginseng obtains Rhizoma Polygonati Odorati and Gai Li, and Rhizoma Polygonati Odorati obtains Radix Ginseng and rouses bravely also.< < Bencao Shiyi > >: " Rhizoma Polygonati Odorati master is clever, and QI and blood regulating makes us strong ".< < book on Chinese herbal medicine is through vegetables > >: " its this alcohol of taste of Rhizoma Polygonati Odorati is good, and abnormal smells from the patient is gentle, therefore can grow money, it is separated, with and infinite ".Therefore auxiliary Radix Ginseng is strengthened the power of YIN nourishing in side, the monarch and his subjects' phase 5, supplementing QI and nourishing YIN complements each other, therefore be main minister, the main active of Rhizoma Polygonati Odorati is steroidal saponin, flavone, alkaloid, polysaccharide etc., has raising immunity of organisms, the effects such as defying age, antitumor.
Bulbus Lilii: be considered as since ancient times " thing of luckiness " by people, so called after Bulbus Lilii is the meaning of getting its " a century is become reconciled " " a century suit and ", nutritive value is high, is the famous and precious product of tonic medicine-food two-purpose, has nourishing YIN and moistening the lung, the effect of clearing away heart-fire for tranquillization.Its sweet in the mouth is cold in nature, shares with Radix Ginseng the effect of can auxiliary monarch strengthening YIN nourishing, can help again the property that Radix Ginseng processed is warm, therefore be adjuvant drug just.Biotin in Bulbus Lilii, alkaloid etc. have the merit of good nourishing, particularly, to body is empty after being ill, the diseases such as neurasthenia have greatly benefit merit, experimental results show that Bulbus Lilii has resisting fatigue, improves the effects such as immunity, anti-stress, tranquillizing and allaying excitement, as the raw material of the product of health care, the utmost point has DEVELOPMENT PROSPECT.
Radix Glycyrrhizae: the flat sweet in the mouth of property, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription, therefore make medicine at Fang Zhongwei.The main effectively active component of Radix Glycyrrhizae is glycyrrhizic acid, enoxolone, flavone compound, has immunoregulation effect, regulation and control lipid metabolism, antioxidation, stress and antiplatelet aggregative activity, combine and bring up its atherosclerosis effect, and the antiplatelet aggregation of Radix Glycyrrhizae and thrombin suppress the anti-thrombosis function forming, can block atherosclerotic development again, so the also title of " state is old " of Radix Glycyrrhizae.
After above-mentioned raw materials coordinates, reduced the property of Radix Ginseng warm-dryness syndrome, the various bodies of health have all been had to certain regulating action.Be applicable to all groups, and fatiguability be primary symptom, immunologic hypofunction, take syndrome of deficiency of both qi and yin as main clinical manifestation person particularly applicable.
The technical scheme that the present invention takes is: be to be made by the raw material of following weight portion:
Radix Ginseng 0.5-5.5 part, Rhizoma Polygonati Odorati 1-19 part, Bulbus Lilii 1-11 part, Radix Glycyrrhizae 0.5-9.5 part.
Preferred:
3 parts of Radix Ginsengs, 10 parts of Rhizoma Polygonati Odorati, 6 parts of Bulbus Liliies, 5 parts, Radix Glycyrrhizae.
The preparation method of active component of the present invention comprises the following steps:
Raw material in formula is cataclasm, adds the decocting of 6 ~ 10 times of amount volumes to boil after mixing, filters filtrate for later use; Residue adds 5 ~ 95% alcohol reflux 2 ~ 3 times of 6 ~ 10 times of amount volumes, and each 2 ~ 6 hours, merge extractive liquid,, filtered, and filtrate recycling ethanol merges with water decoction, continues to be concentrated into the extractum of relative density 1.03 ~ 1.08.
Radix Ginseng of the present invention can be also Radix Ginseng Rubra.
The active component of medicine of the present invention can add various conventional adjuvant required while preparing different dosage form, as disintegrating agent, lubricant, binding agent etc., with conventional method of Chinese medicinal, be prepared into any conventional peroral dosage form, as granule, pill, powder, tablet, capsule, oral liquid etc.
The difference of the report of mentioning in the present invention and background technology be mainly following some: (1) has invented a kind of composition and method of making the same and application thereof of removing the dry property of Radix Ginseng, set forth and adopted the method for traditional Chinese medical science compatibility remove the viewpoint of Radix Ginseng " dry property " and carried out case verification analysis, viewpoint is novel, formula forms few; (2) adopt Radix Ginseng sensitive group (known anthropophagy's ginseng has " getting angry " symptom), after Ethics Committee, the clinical human experiment research of carrying out, research carrier is " The Affiliated Hospital to Changchun University of Chinese Medicine ", research observation index is complete, mainly contains: demographic characteristics's index, clinical safety index, laboratory safety index.
Advantage of the present invention is: under the guidance of theory of Chinese medical science, the property of the warm-dryness syndrome having for Radix Ginseng, carry out science compatibility with the cold and cool property raw material of integration of edible and medicinal herbs, and adopt the preparation method of present Chinese medicine, through clinical experimental study result, show, the product of making by this compatibility and preparation method, reduced the dry property of Radix Ginseng, under the method instructs, the Radix Ginseng of preparation " is not got angry " product long-term taking without the symptom of getting angry, and to a certain extent experimenter's physical function is played to regulating action, have the market competitiveness.Product forms comprises decoction, tablet, granule, capsule, pill, oral liquid, liquid beverage, solid beverage, and product can be for medicine, health food, field of food.
The specific embodiment
The preparation of embodiment 1 tablet of the present invention
Radix Ginseng 5g, Rhizoma Polygonati Odorati 10g, Bulbus Lilii 10g, Radix Glycyrrhizae 5g;
Raw material in formula is cataclasm, adds the decocting of 6 times of amount volumes to boil after mixing, filters filtrate for later use; Residue adds 5% alcohol reflux 2 times of 6 times of amount volumes, and each 2 hours, merge extractive liquid,, filtered, and filtrate recycling ethanol merges with water decoction, continues to be concentrated into the extractum of relative density 1.03, adds the adjuvant of preparing tablet, makes tablet.
The preparation of embodiment 2 granules of the present invention
Radix Ginseng 30g, Rhizoma Polygonati Odorati 100g, Bulbus Lilii 60g, Radix Glycyrrhizae 50g.
Raw material in formula is cataclasm, adds the decocting of 8 times of amount volumes to boil after mixing, filters filtrate for later use; Residue adds 50% alcohol reflux 3 times of 8 times of amount volumes, and each 4 hours, merge extractive liquid,, filtered, and filtrate recycling ethanol merges with water decoction, continues to be concentrated into the extractum of relative density 1.05, adds the adjuvant of preparing granule, granulation agent.
The preparation of embodiment 3 oral liquids of the present invention
Radix Ginseng 55g, Rhizoma Polygonati Odorati 190g, Bulbus Lilii 110g, Radix Glycyrrhizae 95g;
Raw material in formula is cataclasm, adds the decocting of 10 times of amount volumes to boil after mixing, filters filtrate for later use; Residue adds 95% alcohol reflux 3 times of 10 times of amount volumes, and each 6 hours, merge extractive liquid,, filtered, and filtrate recycling ethanol merges with water decoction, continues to be concentrated into the extractum of relative density 1.08.
Radix Ginseng in the above embodiment of the present invention, can replace with Radix Ginseng Rubra, and all the other are all constant.
Below by concrete clinical experiment example, further illustrate effect of the present invention.
With brief description human experiment experimentation:
The selection of 1 trial volunteer and exiting
1.1 inclusive criteria
Health volunteer.
Age is in 18～60 years old (containing 18 years old and 60 years old), male or female.
Body Mass Index (BMI) is at 19～24[BMI=body weight (kg)/height 2(m2)] in scope.
4. through physical examination blood pressure, electrocardiogram, breath state and liver, renal function, hematuria is just conventional all without abnormal (or person judges without clinical meaning after deliberation).
5. sign Informed Consent Form, tested voluntarily.
6. early stage, Radix Ginseng test-meal test showed " getting angry " symptom.
1.2 exclusion standard
Be associated with primary disease, the psychotics such as serious cardiovascular, liver, kidney and blood system.
Gestation or preparation gestation or women breast-feeding their children.
Allergic constitution person, as to two kinds or above medicine or food anaphylaxis, or known to Radix Ginseng component allergy sufferers.
4. systolic pressure >=140mmhg and (or) diastolic pressure >=90mmhg.
5. researcher is thought and can not be entered other experimenter of group.
1.3 reject, standard comes off
(1) the judgement coming off: allly filled in Informed Consent Form and screened the qualified experimenter who carries out test-meal test, all had the right to exit at any time test, no matter when what is because of exiting, as long as no completing the omnidistance observation of test, is the case that comes off.The common reason that comes off: 1. adverse events; 2. run counter to testing program (comprising that compliance is poor); 3. (comprising that experimenter exits voluntarily) lost to follow-up; 4. experimenter recalls Informed Consent Form; 5. other.
(2) person's processing does not come off: after experimenter comes off, researcher must be filled in the reason that comes off in summary sheet, and contacts with experimenter as far as possible, completes the evaluation item that can complete, and record is taken the time that is subject to test product for the last time as far as possible.To because adverse events comes off, through following up a case by regular visits to last judgement and being subject to the relevant person of test product, must record and notify main researcher.
(3) rejecting person's processing: once enter to organize the one that experimenter meets following situation, should reject: 1. by mistake receive; 2. meet exclusion standard; 3. not with the person that is subject to test product; 4. without any detection record person.Rejecting person answers illustration, and its observed and recorded should retain.Depending on violating the serious situation of above-mentioned standard, by data check meeting, determine whether this case includes statistical analysis in.
1.4 experimenters exit condition and the step of test
(1) what researcher determined exits: experimenter exits test and refers to that the in the situation that test having appearred proceeding in selected experimenter in process of the test, researcher determines that this experimenter exits test.1. in process of the test, experimenter has occurred that major disease or special physiological change, and are not suitable for continuing reception test.2. in test, experimenter's compliance is poor, use be subject to test product do not reach ormal weight 80% or surpass 120% of ormal weight.
(2) experimenter exits test voluntarily: experimenter has the right to drop by the wayside test, though or experimenter clearly do not propose to exit test, no longer accept to take and be subject to test product and detection and lost to follow-up, also belong to " exiting ".Should understand as far as possible it and exit reason, and record in addition.
(3) exit the processing of test: which kind of reason no matter, to exiting the observed and recorded of test, should preserve, and take its last testing result and carry down as final result and analyze.
2 tested product schedule of administration
(1) instructions of taking: being subject to test product is the product obtaining by the formula of recording in description of the present invention and method, every day 1 time.
(2) take the course for the treatment of: 4 weeks.
(3) during taking, require: nothing.
3 observation index and observation time point
(1) demographic characteristics: sex, age, height, body weight, nationality, occupation (muscle power and non-muscle power).Height, body weight are measured when screening.
(2) clinical safety index
1. the mental status, sleep quality.
2. seminal emission (man) and menstruation (female).
3. ingest and amount of drinking water.
4. dizziness, tinnitus, conjunctival congestion, nasopharynx be dry itch and pain, epistaxis, near the eyes secretions and aphtha of the mouth and tongue, dysphoria with feverish sensation in the chest palms and soles, red urine, be hard and dry, erythra etc.
5. body temperature, blood pressure, changes in heart rate.
6. other are abnormal: the disease occurring in test, syndrome etc., record its time of origin, the order of severity and processing method at any time.
Above index is in taking front and taking afterwards and respectively once make a house call for the 2nd, 4,6,8,10,12 weeks.
(3) laboratory safety index
1. conventional, the routine urinalysis of routine blood test, blood coagulation, liver function, blood biochemical are learned and are checked, comprising: ALT, AST, BUN, Cr respectively once check after 2 weeks and off-test before taking, after taking.
2. electrocardiogram is respectively once observed after 2 weeks and off-test before taking, after taking.
3. just conventional in take front and take after respectively once observe.
4. for taking in process, occur bleeder optionally checking that blood coagulation is conventional.
If there is any exceptional value that has clinical meaning after taking, all should follow up a case by regular visits to normally.
(4) take the compliance that is subject to test product.
4 enter group situation
This test, plans into 8 of group health volunteers, actually enters to organize 8 of experimenters.All cases is all signed Informed Consent Form.
5 clinical safety observed results
5.1 mental status, sleep quality
In research process, at 2,4 weeks, respectively make a house call a little, all experimenter's mental status are all normal; At 2 weeks～4 weeks, all there is not the situation that sleep is poor.
5.2 other reactions
In research process, at 2,4 weeks, respectively make a house call a little, do not find that dizziness, conjunctival congestion, dryness in the nasal cavity are itched, dry pharynx is itched, dry stool, red urine, allergy, erythra, tinnitus, nose pain, epistaxis, pharyngalgia, the reaction such as secretions, aphtha of the mouth and tongue, feverish sensation in the palms and soles near the eyes greatly.
5.3 analysis of experimental data
Take after this product, experimenter's laboratory examination results slightly changes, but all within normal range.Through relative analysis, the laboratory data index analysis and summary with variation tendency are as follows:
5.3.1 routine blood test: in 8 test-meal volunteers' routine blood test examining report, red blood cell count(RBC), hemoglobin and platelet count change before and after taking.Red blood cell count(RBC) and hemoglobin are taken front all risings after taking, prompting is maintaining under blood circulation stable state, has improved the oxygen carrying capacity of cell.Platelet count raises, and bone marrow hematogenesis is increased, and tends to increase blood coagulation ability.Concrete condition is in Table 1.
Routine blood test testing result before and after table 1 test-meal
Routine blood test testing result before and after table 1 test-meal
5.3.2 blood coagulation is conventional: prothrombin time, Fibrinogen decline, and partial prothrombinase time, thrombin time raise, and considers that body coagulation changes, and coagulation function reduces, and has bleeding tendency, and body can be compensatory.Concrete condition is in Table 2.
Blood coagulation conventional sense result before and after table 2 test-meal
5.3.3 liver function: total protein, albumin raise, and can improve plasma colloid osmotic pressure, reduce hemorrhage probability.Glutamate pyruvate transaminase, glutamic oxaloacetic transaminase, GOT, alkali phosphatase reduce, prompting hepatocytoprotection.Concrete condition is in Table 3.
Liver function test result before and after table 3 test-meal
6, brief summary
MethodsThe cases enrolled is health volunteer, and baseline is not found clinical safety Indexes Abnormality.After test-meal, within 2～4 weeks, respectively make a house call a little, each clinical safety index observing result is as follows.
(1) mental status, sleep quality: all experimenter's mental status is all normal.
(2) seminal emission and change in menstrual cycle: all the record of seminal emission does not all appear in male subject; In female subjects, there is not change in menstrual cycle.
(3) amount of drinking water and the situation of ingesting: all experimenters' situation of drinking water is all normal.
(4) allergy, erythra, dizziness, tinnitus, conjunctival congestion, dryness in the nasal cavity are itched, nose pain, epistaxis, dry pharynx are itched, pharyngalgia, the reaction such as secretions, aphtha of the mouth and tongue, feverish sensation in the palms and soles, large dry stool, red urine near the eyes: all experimenter's situations are all normal.
(5) by continuing observed result and show taking the existing obviously experimenter of " getting angry " symptom of Radix Ginseng, Radix Ginseng " is not got angry " product by science compatibility, has weakened the dry property of Radix Ginseng, has expanded the crowd of taking.
(6) experimenter's laboratory examination results slightly changes, but all within normal range.
Claims (5)
1. remove a compositions for the dry property of Radix Ginseng, it is characterized in that being made by the raw material of following weight portion:
Radix Ginseng 0.5-5.5 part, Rhizoma Polygonati Odorati 1-19 part, Bulbus Lilii 1-11 part, Radix Glycyrrhizae 0.5-9.5 part.
2. a kind of compositions of removing the dry property of Radix Ginseng according to claim 1, it is characterized in that being made by the raw material of following weight portion:
3 parts of Radix Ginsengs, 10 parts of Rhizoma Polygonati Odorati, 6 parts of Bulbus Liliies, 5 parts, Radix Glycyrrhizae.
3. a kind of compositions of removing the dry property of Radix Ginseng according to claim 1 and 2, is characterised in that Radix Ginseng can be also Radix Ginseng Rubra.
4. a kind of preparation method of removing the compositions of the dry property of Radix Ginseng as claimed in claim 1, is characterized in that comprising the following steps:
Raw material in formula is cataclasm, adds the decocting of 6 ~ 10 times of amount volumes to boil after mixing, filters filtrate for later use; Residue adds 5 ~ 95% alcohol reflux 2 ~ 3 times of 6 ~ 10 times of amount volumes, and each 2 ~ 6 hours, merge extractive liquid,, filtered, and filtrate recycling ethanol merges with water decoction, continues to be concentrated into the extractum of relative density 1.03 ~ 1.08.
5. a kind of preparation method of removing the compositions of the dry property of Radix Ginseng according to claim 4, is characterized in that the Radix Ginseng in formula can be also Radix Ginseng Rubra.
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Cited By (7)
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| CN107441332A (en) * | 2017-08-05 | 2017-12-08 | 刘建明 | The ginseng composition and preparation method of auxiliary adjustment endocrine metabolism and anti-cancer and cancer-preventing |
| CN107581336A (en) * | 2016-07-06 | 2018-01-16 | 辽宁中书堂黑参有限公司 | A kind of honey makes black ginseng and its preparation method |
| CN107616497A (en) * | 2017-11-13 | 2018-01-23 | 绵阳丰邱涵蒙农业科技有限公司 | A kind of cucumber ferment powder and preparation method thereof |
| CN107951018A (en) * | 2016-10-14 | 2018-04-24 | 中国中医科学院中药研究所 | Ginseng improved composition, modified ginseng and its preparation method and application |
| CN109394806A (en) * | 2017-08-15 | 2019-03-01 | 成都体九生物科技有限公司 | The processing method of ginseng radix polygonati officinalis |
| CN112056473A (en) * | 2020-09-30 | 2020-12-11 | 黑龙江北草堂中药材有限责任公司 | Composition and beverage for enhancing immunity and preparation method |
| CN115252666A (en) * | 2022-06-23 | 2022-11-01 | 广东官栈营养健康科技有限公司 | Ginseng slice without excessive internal heat and processing method thereof |
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| CN103396920A (en) * | 2013-07-30 | 2013-11-20 | 孟宗科 | Preparation method of ginseng healthcare wine |
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| CN107581336A (en) * | 2016-07-06 | 2018-01-16 | 辽宁中书堂黑参有限公司 | A kind of honey makes black ginseng and its preparation method |
| CN107951018A (en) * | 2016-10-14 | 2018-04-24 | 中国中医科学院中药研究所 | Ginseng improved composition, modified ginseng and its preparation method and application |
| CN107441332A (en) * | 2017-08-05 | 2017-12-08 | 刘建明 | The ginseng composition and preparation method of auxiliary adjustment endocrine metabolism and anti-cancer and cancer-preventing |
| CN109394806A (en) * | 2017-08-15 | 2019-03-01 | 成都体九生物科技有限公司 | The processing method of ginseng radix polygonati officinalis |
| CN109394806B (en) * | 2017-08-15 | 2021-07-23 | 成都体九生物科技有限公司 | Processing method of ginseng and polygonatum odoratum |
| CN107616497A (en) * | 2017-11-13 | 2018-01-23 | 绵阳丰邱涵蒙农业科技有限公司 | A kind of cucumber ferment powder and preparation method thereof |
| CN112056473A (en) * | 2020-09-30 | 2020-12-11 | 黑龙江北草堂中药材有限责任公司 | Composition and beverage for enhancing immunity and preparation method |
| CN115252666A (en) * | 2022-06-23 | 2022-11-01 | 广东官栈营养健康科技有限公司 | Ginseng slice without excessive internal heat and processing method thereof |
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Application publication date: 20141119 |