CN109393148A - Reduce livestock and poultry diarrhea, the pre-mixing agent for improving efficiency of feed utilization and preparation method thereof - Google Patents
Reduce livestock and poultry diarrhea, the pre-mixing agent for improving efficiency of feed utilization and preparation method thereof Download PDFInfo
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- CN109393148A CN109393148A CN201811576860.4A CN201811576860A CN109393148A CN 109393148 A CN109393148 A CN 109393148A CN 201811576860 A CN201811576860 A CN 201811576860A CN 109393148 A CN109393148 A CN 109393148A
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- mixing agent
- glutamine
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
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- Biotechnology (AREA)
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Abstract
The present invention relates to a kind of reduction livestock and poultry diarrheas, the pre-mixing agent for improving efficiency of feed utilization and preparation method thereof, raw material including following parts by weight: probiotics, glutamine and enzyme preparation, wherein, the probiotics includes Bifidobacterium, Lactobacillus acidophilus, clostridium butyricum, bacillus subtilis, Ross Salmonella and clostridium butyricum；The enzyme preparation includes arabinofuranosidase, feruloyl esterase and endoxylanase；The glutamine is glutamine granules.Compared with prior art, pre-mixing agent of the present invention is using probiotics, glutamine and enzyme preparation as raw material, the intestinal health for promoting livestock and poultry is horizontal, efficiency of feed utilization can be improved, immunity of organisms can be enhanced again, reduce inflammatory reaction, prevention or alleviating diarrhoea, to reduce the use of antibiotic, the production performance of livestock and poultry is promoted.
Description
Technical field
The invention belongs to feed additive fields, more particularly, to a kind of reduction livestock and poultry diarrhea, improve efficiency of feed utilization
Pre-mixing agent and preparation method thereof.
Background technique
Under market environment, the price of corn is increased, and the ratio regular meeting of wheat increases considerably in animal and fowl fodder formula, however
Contain a large amount of araboxylan in wheat, will cause livestock and poultry and be unable to fully absorb the nutritional ingredient in feed, daily gain subtracts
Less, feedstuff-meat ratio increases, in addition, in the breeding process, diarrhea disease causes great harm the health of livestock and poultry, causes huge
Economic loss keeps intestinal health that can effectively prevent the generation of diarrhea disease, improves nutrition by optimizing intestinal flora
It absorbs, most of pre-mixing agent only focuses on the absorbability for improving for feed nutrient and ignoring enteron aisle.
Chinese patent CN108065092A discloses a kind of feed addictive for keeping intestine of young pigs health, including following original
Material: 18-24 parts of sepiolite powder, 2-6 parts of enzyme preparation, 1-5 parts of probiotics, 4-8 parts of L-Glutamine, 1-3 parts of dipotassium glycyrrhizinate, coconut palm
0.2-0.6 parts of seed oil, 0.1-0.3 parts of Salanesol, can effectively avoid the destruction to intestinal villi, and fuzzy surface keeps high density
Finger-like makes it have biggish digestion and absorption area, and then guarantees do not adding antibiosis to the abilities of digestive and absorption of nutriment
In the case where element, the diarrhea of pig is effectively controlled, promotes the growth of sucking pig, but its enzyme preparation and probiotic composition are single, feed adds
Add agent effect and bad.
Summary of the invention
The purpose of the present invention is to solve the above-mentioned problems and provides a kind of reduction livestock and poultry diarrhea, improves efficiency of feed utilization
Pre-mixing agent and preparation method thereof.
The purpose of the present invention is achieved through the following technical solutions:
A kind of pre-mixing agent for reducing livestock and poultry diarrhea, improving efficiency of feed utilization, the raw material including following parts by weight: 2-6 parts of benefits
Raw bacterium, 3-8 part glutamine and 4-6 parts of enzyme preparations, wherein the probiotics includes Bifidobacterium, Lactobacillus acidophilus, butyric acid
Clostridium, bacillus subtilis, Ross Salmonella and clostridium butyricum；Probiotics is the mixing of listed each strain.
The enzyme preparation includes arabinofuranosidase, feruloyl esterase and endoxylanase.Preferably, Ah
The mass ratio for drawing primary furanoside enzyme, feruloyl esterase and endoxylanase is 1:1:1.
Preferably, the endoxylanase is selected from GH10 endoxylanase or GH11 endoxylanase.
The glutamine is glutamine granules.
A kind of preparation method for the pre-mixing agent for reducing livestock and poultry diarrhea, improving efficiency of feed utilization, is by probiotics, glutamine
It is mixed to prepare with enzyme preparation.
The mechanism of action of pre-mixing agent of the present invention are as follows: enzyme preparation is (in arabinofuranosidase, feruloyl esterase and xylan
Enzyme cutting) anti-nutritional factors non-starch polysaccharide --- araboxylan in the feed that can effectively degrade, enzymolysis product is oligomeric
Xylose can promote a variety of bacterial multiplications for generating butyrate in enteron aisle, while add probiotics (the bifid bar for producing butyrate
Bacterium, Lactobacillus acidophilus, clostridium butyricum, bacillus subtilis, Ross Salmonella and clostridium butyricum etc.), increase enteron aisle
The concentration of Short-Chain Fatty Acids such as butyric acid.Short chain fatty acids are for maintaining the normal function of large intestine and the form of colon epithelial cell
Play a significant role with function, short chain fatty acids may additionally facilitate the absorption of sodium, and the effect of butyric acid in this respect is than acetic acid and propionic acid
Stronger and butyric acid can increase the yield of Bacillus acidi lactici and reduce the quantity of Escherichia coli, to effectively adjust the enterobacteriaceae of livestock and poultry
Group structure, then combine glutamine, promote enteron aisle to the absorbability of nutrition.Glutamine is maintaining the complete of gut barrier
Property in play a significant role, can by P13K/Akt signal path regulate and control enterocyte between closely connect, promote intestinal mucosa
Cell turnover and regeneration, the intestinal health for promoting livestock and poultry is horizontal, improves efficiency of feed utilization, and enhances immunity of organisms reduction
Inflammation, prevention or alleviating diarrhoea promote the production performance of livestock and poultry to reduce the use of antibiotic.
For pre-mixing agent of the present invention using probiotics, glutamine and enzyme preparation as raw material, the intestinal health for promoting livestock and poultry is horizontal,
Efficiency of feed utilization can be improved and enhance immunity of organisms, reduce inflammatory reaction, prevention or alleviating diarrhoea are to reduce antibiosis
The use of element, promotes the production performance of livestock and poultry.Can increase probiotics quantity in enteron aisle, reduce Escherichia coli, salmonella and
The quantity of the spoilage organisms such as C.perfringens；Production performance can be promoted, feed intake and daily gain are increased, reduces feedstuff-meat ratio, prevention
Or alleviating diarrhoea；It can inhibit inflammatory reaction, reduce T lymphocyte infiltration；Can reparative regeneration damaged intestine mucous membrane, increase enteron aisle in
The short-chain fats acid content such as butyric acid.
The main chain of endoxylanase degrading enzyme araboxylan, arabinofuranosidase and feruloyl esterase can
Degrade araboxylan branch, and single enzyme can not degradable araboxylan, so that I can not thoroughly be utilized
The catabolite xylo-oligosaccharide of primary xylan influences digestion and absorption of the livestock and poultry to feed.A variety of probiotics mutually act synergistically can
The growth for inhibiting harmful bacteria, resists the infection of pathogen, and the vitamin that synthesis animal body needs promotes the suction to minerals
It receives, various probiotics can also generate other different organic acids and short chain fatty acids, such as acetic acid, cream other than producing butyric acid respectively
Acid, acetic acid and propionic acid etc. can stimulate intestines peristalsis, promote defecation, prevent constipation and inhibit enteron aisle putrefaction, purification intestines
Road environment can also decompose carcinogen, stimulation immune system, to improve disease resistance etc..
Compared with prior art, the invention has the characteristics that:
1) present invention uses three kinds of enzyme synergy, while cutting the main chain and branch of araboxylan, relative to
The use of single enzyme, anti-nutritional factors non-starch polysaccharide --- the araboxylan in the feed that can more fully degrade；
2) probiotics is added in pre-mixing agent, requires compounding oligosaccharide generally to promote proliferation of probiotics, and it is of the invention
According to the characteristic of the catabolite of araboxylan, the probiotics that cooperation produces butyrate is used, by nutrient absorption anti-in feed
Araboxylan be changed into the xylo-oligosaccharide for promoting growth of probiotics, the utilization rate of feed, save the cost and high can be improved
Effect adjusts intestinal microflora, increases enteron aisle Short-Chain Fatty Acids concentration；
3) most of pre-mixing agent focuses on the perfect of feed nutrient, and ignores the absorbability of enteron aisle, in the present invention
Glutamine can repair the intestinal mucosa with regeneration of damaged, reduce inflammatory reaction, improve the immunity of enteron aisle, enhance enteron aisle
Absorbability.
Specific embodiment
The present invention is described in detail combined with specific embodiments below, but should be in no way restrictive
Embodiment 1
The present embodiment pre-mixing agent is mixed to prepare by 2 parts of probiotics, 3 parts of glutamine granules and 4 parts of enzyme preparations, wherein benefit
Raw bacterium bag includes Bifidobacterium, Lactobacillus acidophilus, clostridium butyricum, bacillus subtilis, Ross Salmonella and butyric acid shuttle
Bacterium, each strain are mixed, and enzyme preparation includes that mass ratio is poly- for the arabinofuranosidase, feruloyl esterase and wood of 1:1:1
Sugared restriction endonuclease, endoxylanase are GH10 endoxylanase or GH11 endoxylanase.
500 1 aa broiler chickens are divided into 2 groups (male and female ratio is identical), respectively blank control group, addition pre-mixing agent
Test group, feed the daily ration of identical wheat-dregs of beans configuration.Pre-mixing agent 36d, on-test and examination are continuously added in daily ration
It weighs at the end of testing to two groups, calculates the average daily gain of two groups of broiler chicken；Two groups of total consumption is counted when off-test respectively
Doses calculates average daily gain；10 broiler chicken are randomly selected when off-test in two groups and carry out dissect, survey butyric acid in caecum
Content.Observation growth of meat chicken situation is paid attention to daily.Test result is as shown in table 1.
1 AA meat chicken production performance of table and intestinal health situation
As it can be seen from table 1 test group can increase, broiler chicken is only weighed and daily gain, promotion feed intake reduce meat feed ratio,
Butyric acid content increases, and shows growing state that pre-mixing agent of the invention can make livestock and poultry and intestinal health more preferably.
Embodiment 2
The present embodiment pre-mixing agent is mixed to prepare by 6 parts of probiotics, 8 parts of glutamine granules and 6 parts of enzyme preparations, wherein benefit
Raw bacterium bag includes Bifidobacterium, Lactobacillus acidophilus, clostridium butyricum, bacillus subtilis, Ross Salmonella and butyric acid shuttle
Bacterium, each strain are mixed, and enzyme preparation includes that mass ratio is poly- for the arabinofuranosidase, feruloyl esterase and wood of 1:1:1
Sugared restriction endonuclease, endoxylanase are GH10 endoxylanase or GH11 endoxylanase.
86 Ternary Pig child care pigs that this test selects health status, weight close, are randomly divided into 2 groups, respectively blank
Control group, the test group for adding pre-mixing agent feed identical wheat-dregs of beans configuration daily ration.Every group 43, test 21d, test
It weighs when starting with off-test to two groups, calculates the average daily gain of two groups of child care pigs；It is counted respectively when off-test
Two groups of total feed consumption amount calculates average daily gain；Statistics each group child care diarrhea of pigs head number, diarrhea rate=experimental period, are each heavy daily
Add up the total head number of diarrhea/(experimental period respectively repeats total head number × test number of days) × l00% again.Test result is as shown in table 2.
2 child care diarrhea of pigs of table and production performance situation
From table 2 it can be seen that test group is compared with the control group, diarrhea rate decline, daily gain increases, and feedstuff-meat ratio reduces, table
Bright pre-mixing agent of the invention can reduce livestock and poultry diarrhea, enhance premunition, improve production performance.
The above description of the embodiments is intended to facilitate ordinary skill in the art to understand and use the invention.
Person skilled in the art obviously easily can make various modifications to these embodiments, and described herein general
Principle is applied in other embodiments without having to go through creative labor.Therefore, the present invention is not limited to the above embodiments, ability
Field technique personnel announcement according to the present invention, improvement and modification made without departing from the scope of the present invention all should be of the invention
Within protection scope.
Claims (6)
1. a kind of pre-mixing agent for reducing livestock and poultry diarrhea, improving efficiency of feed utilization, which is characterized in that the original including following parts by weight
Material: 2-6 parts of probiotics, 3-8 parts of glutamine and 4-6 parts of enzyme preparations, wherein the probiotics includes Bifidobacterium, acidophilus cream
Acidfast bacilli, clostridium butyricum, bacillus subtilis, Ross Salmonella and clostridium butyricum；The enzyme preparation includes Arab
Furanoside enzyme, feruloyl esterase and endoxylanase.
2. a kind of pre-mixing agent for reducing livestock and poultry diarrhea, improving efficiency of feed utilization according to claim 1, which is characterized in that
The mass ratio of the arabinofuranosidase, feruloyl esterase and endoxylanase is 1:1:1.
3. a kind of pre-mixing agent for reducing livestock and poultry diarrhea, improving efficiency of feed utilization according to claim 1, which is characterized in that
The endoxylanase is selected from GH10 endoxylanase or GH11 endoxylanase.
4. a kind of pre-mixing agent for reducing livestock and poultry diarrhea, improving efficiency of feed utilization according to claim 1, which is characterized in that
The glutamine is glutamine granules.
5. a kind of pre-mixing agent for reducing livestock and poultry diarrhea, improving efficiency of feed utilization according to claim 1, which is characterized in that
The probiotics be by uniformly match Bifidobacterium, Lactobacillus acidophilus, clostridium butyricum, bacillus subtilis,
The mixing of Ross Salmonella and clostridium butyricum.
6. a kind of preparation method of pre-mixing agent for reducing livestock and poultry diarrhea, improving efficiency of feed utilization as described in claim 1, special
Sign is, probiotics, glutamine and enzyme preparation are mixed to prepare.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811576860.4A CN109393148A (en) | 2018-12-23 | 2018-12-23 | Reduce livestock and poultry diarrhea, the pre-mixing agent for improving efficiency of feed utilization and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811576860.4A CN109393148A (en) | 2018-12-23 | 2018-12-23 | Reduce livestock and poultry diarrhea, the pre-mixing agent for improving efficiency of feed utilization and preparation method thereof |
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| CN109393148A true CN109393148A (en) | 2019-03-01 |
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| CN201811576860.4A Pending CN109393148A (en) | 2018-12-23 | 2018-12-23 | Reduce livestock and poultry diarrhea, the pre-mixing agent for improving efficiency of feed utilization and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110178972A (en) * | 2019-04-29 | 2019-08-30 | 山东苏柯汉生物工程股份有限公司 | A kind of white feather chicken raising probiotics and preparation method thereof |
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