CN109387419A - A kind of dyeing of microsection manufacture and scanning integrated machine - Google Patents
A kind of dyeing of microsection manufacture and scanning integrated machine Download PDFInfo
- Publication number
- CN109387419A CN109387419A CN201811480003.4A CN201811480003A CN109387419A CN 109387419 A CN109387419 A CN 109387419A CN 201811480003 A CN201811480003 A CN 201811480003A CN 109387419 A CN109387419 A CN 109387419A
- Authority
- CN
- China
- Prior art keywords
- integrated machine
- test tube
- microsection manufacture
- scanning
- scanning integrated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004043 dyeing Methods 0.000 title claims abstract description 25
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 23
- 230000007246 mechanism Effects 0.000 claims abstract description 33
- 238000012360 testing method Methods 0.000 claims abstract description 30
- 230000007306 turnover Effects 0.000 claims abstract description 10
- 238000002156 mixing Methods 0.000 claims abstract description 9
- 238000011010 flushing procedure Methods 0.000 claims abstract description 4
- 238000001179 sorption measurement Methods 0.000 claims abstract description 4
- 239000003153 chemical reaction reagent Substances 0.000 claims description 15
- 239000011521 glass Substances 0.000 claims description 10
- 239000012472 biological sample Substances 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 238000013095 identification testing Methods 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 7
- 230000008569 process Effects 0.000 abstract description 5
- 230000000694 effects Effects 0.000 abstract description 2
- 230000010354 integration Effects 0.000 abstract description 2
- 238000010586 diagram Methods 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 239000000523 sample Substances 0.000 description 4
- 210000000349 chromosome Anatomy 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000010186 staining Methods 0.000 description 2
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000007605 air drying Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 1
- 230000005622 photoelectricity Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention discloses a kind of dyeing of microsection manufacture and scanning integrated machines, it solves the problems, such as that time-consuming, operator is needed to cooperate in microsection manufacture process in the prior art, with dyeing, the flushing, air dry operation that can complete slice, and can automatically scanning be sliced and handle, the effect that integration degree is high；Its technical solution are as follows: including centrifugal device, positioning and recognizing device, automatic pipetting device, slide displacing mechanism, dye sheet devices and automatic scanning system, install test tube flat inside centrifugal device, test tube flat is connected with vibration evenly mixing device；Positioning and recognizing device includes gear indexing mechanism and color sensor；Automatic pipetting device includes electric pipettor, and the electric pipettor drives its movement by linear movement module；Slide displacing mechanism is installed on linear movement module side, including sucker, and the sucker provides adsorption capacity by pneumatic mechanism；Dye sheet devices include turnover device, automatic scanning system, for scanning through dye piece treated slice information.
Description
Technical field
The present invention relates to microsection manufacture field more particularly to a kind of dyeing of microsection manufacture and scanning integrated machines.
Background technique
Although section preparation manufacturing technology is operating technology very basic in biology, but due to the individual of biomaterial
Difference, the diversity of chemical reagent, therefore operating process is very careful, complicated.
Existing microsection manufacture equipment generally requires operator's cooperation, and it is a variety of cannot to complete reagent mixing, drop piece, dyeing etc.
Operation, time-consuming, it is thus impossible to meet increasingly developed medicine, biological requirement.
Summary of the invention
For overcome the deficiencies in the prior art, the present invention provides a kind of dyeing of microsection manufacture and scanning integrated machine, tools
Have can complete slice dyeing, flushing, air dry operation, and can automatically scanning be sliced and handle, the effect that integration degree is high
Fruit.
The present invention adopts the following technical solutions:
A kind of dyeing of microsection manufacture and scanning integrated machine, comprising:
Centrifugal device, internal to install test tube flat, test tube flat is connected with for being uniformly mixed reagent with biological sample
Vibrate evenly mixing device；
Positioning and recognizing device, including the gear indexing mechanism for realizing test tube flat fine rotational and for identification test tube flat
The color sensor of position；
Automatic pipetting device, including electric pipettor, the electric pipettor drive its movement by linear movement module；
Slide displacing mechanism is installed on linear movement module side, described including the sucker for drawing and placing slice
Sucker provides adsorption capacity by pneumatic mechanism；
Sheet devices are contaminated, including the dyeing of slice being can be realized, flushing, being air-dried for driving the turnover device of slicing motion
Operation；
Automatic scanning system, for scan, handle through dye piece treated slice.
Further, the vibration evenly mixing device includes vibrating motor, and the vibrating motor is connected with test tube flat.
Further, the positioning and recognizing device is installed on above centrifugal device, including shell, the installation of gear indexing mechanism
It is connected in enclosure interior and with test tube flat.
Further, the linear movement module include move left and right device, with move left and right the front and back that device is connected and move
Dynamic device moves up and down device with what back-and-forth motion device was connected.
Further, described to move up and down there are two devices, it is connected respectively with automatic pipetting device, slide displacing mechanism.
Further, the pneumatic mechanism includes air pump, and the air pump is connected by conduit with sucker, is pacified on the conduit
Three-way magnetic valve equipped with control gas flow.
Further, vacuum generator and vacuum filter are installed between the three-way magnetic valve and air pump.
Further, the dye sheet devices include multiple dye film traps, and turnover device is installed on above dye film trap comprising more
A turning groove, the turning groove are connected by flip-arm with overturning steering engine.
Further, the dye film trap side is equipped with drop film trap, air-dries slot, flushed channel, slice cabin, glass slide cabin and reagent
Feeding mechanism.
Further, water pump is equipped in the flushed channel, the air-dried slot configures blower.
Compared with prior art, the beneficial effects of the present invention are:
(1) centrifugal device of the invention and positioning and recognizing device cooperate, can be realized the biological sample that is held in test tube with
Reagent is sufficiently mixed, and improves accuracy；
(2) present invention setting linear movement module, can be realized electronic liquid-drop machine, sucker automatically moves, to realize
The dropping liquid operation of slice, slice automatically move operation, do not need manual intervention, high degree of automation.
Detailed description of the invention
The accompanying drawings constituting a part of this application is used to provide further understanding of the present application, and the application's shows
Meaning property embodiment and its explanation are not constituted an undue limitation on the present application for explaining the application.
Fig. 1 is axonometric drawing of the invention；
Fig. 2 is main view of the invention；
Fig. 3 is top view of the invention；
Fig. 4 is side view of the invention；
Fig. 5 is mobile device structural schematic diagram of the invention；
Fig. 6 is automatic pipetting device structural schematic diagram of the invention；
Fig. 7 is centrifugal device structural schematic diagram of the invention；
Fig. 8 is positioning and recognizing device structural schematic diagram of the invention；
Fig. 9 is that drop of the invention contaminates device top view；
Figure 10 is that drop of the invention contaminates device main view；
Figure 11 is that drop of the invention contaminates device side view；
Figure 12 is slice cabin structure schematic diagram of the invention；
Figure 13 is glass slide cabin structure schematic diagram of the invention；
Wherein, 1- automatic scanning system, 2- centrifugal device, 3- move left and right device, and 4- is moved forward and backward device, moves down on 5-
Dynamic device, 6- contaminate sheet devices, 7- positioning and recognizing device, 8- electric pipettor, 9- automatic pipetting device, 10- glass slide cabin, 11-
Film trap, 12- touch screen integrated machine are dripped, 13- is sliced cabin, and 14- contaminates film trap, 15- agent delivery device, and 16- vibrates evenly mixing device,
17- cover board, 18- flip-arm, 19- overturn steering engine, and 20- air-dries slot, 21- flushed channel, 22- air pump, 23- vacuum filter, 24- tooth
Wheel, 25- vacuum generator, 26- three-way magnetic valve, 27- sucker, 28- centrifugal rotor, 29- vibrating motor, 30- test tube, 31- examination
Tube socket, 32- are centrifuged cabin, 33- stepper motor, 34- toothed disc, 35- color sensor, 36- shell, 37- color disk.
Specific embodiment
It is noted that following detailed description is all illustrative, it is intended to provide further instruction to the application.Unless another
It indicates, all technical and scientific terms used herein has usual with the application person of an ordinary skill in the technical field
The identical meanings of understanding.
It should be noted that term used herein above is merely to describe specific embodiment, and be not intended to restricted root
According to the illustrative embodiments of the application.As used herein, unless the context clearly indicates otherwise, otherwise singular
Also it is intended to include plural form, additionally, it should be understood that, when in the present specification using term "comprising" and/or " packet
Include " when, indicate existing characteristics, step, operation, device, component and/or their combination.
As background technique is introduced, microsection manufacture process exists in the prior art, and time-consuming, operator is needed to match
The deficiency of conjunction, in order to solve technical problem as above, present applicant proposes a kind of dyeing of microsection manufacture and scanning integrated machines.
In a kind of typical embodiment of the application, as shown in Fig. 1-Figure 13, provide a kind of dyeing of microsection manufacture with
Scanning integrated machine, including centrifugal device 2, positioning and recognizing device 7, automatic pipetting device 9, slide displacing mechanism, dye 6 and of sheet devices
Automatic scanning system 1.
Wherein, automatic pipetting device 9, slide displacing mechanism are installed on 6 top of dye sheet devices, and centrifugal device 2 is set to dye piece
6 side of device, positioning and recognizing device 7 are installed on 6 top of dye sheet devices, and automatic scanning system 1 is located at dye 6 other side of sheet devices.
Centrifugal device 2 uses centrifuge, as shown in fig. 7, comprises centrifugation cabin 32, is centrifuged at the top of cabin 32 and installs cover board 17；From
Centrifugal rotor 28 is installed, centrifugal rotor 28 is connected with test tube flat 31, rotates by centrifugal rotor 28 and drives test tube inside heart cabin 32
Seat 31 rotates.
The test tube flat 31 has multiple, including middle standing pillar, and middle standing pillar circumferentially connects multiple symmetrical pedestals, institute
It states pedestal and offers through-hole for holding test tubes 30.
Biological sample in test tube 30, in order to increase the contact area that sample has reagent, needs to accelerate after reagent is added
The two mixes；Therefore, the configuration of test tube flat 31 vibration evenly mixing device 16 is installed on test tube flat 31 by the vibration realization of evenly mixing device 16
In 30 interior reagent of test tube and sample be uniformly mixed.
Further, the vibration evenly mixing device 16 is vibrating motor 29.
In test tube 30 when sample centrifugal treating, the motor in centrifuge is difficult to that test tube flat 31 is accurately transferred to specific angle
It spends, and can not also identify the position of test tube 30 after centrifugal rotation, be unfavorable for that reagent is added into test tube 30.
Therefore, the application installs positioning and recognizing device 7 above centrifugal device 2, and positioning and recognizing device 7 is as shown in figure 8, packet
Shell 36 is included, gear indexing mechanism is installed inside shell 36, the gear indexing mechanism is connected with the middle standing pillar of test tube flat 31,
For realizing the fine rotational of test tube flat 31.
The gear indexing mechanism includes stepper motor 33, gear 24 and toothed disc 34, stepper motor 33 and 24 phase of gear
Even, gear 24 is engaged with toothed disc 34.
Color disk 37 is installed above toothed disc 34, color sensor 35 is installed on the color disk 37, is sensed by color
Device 35 identifies the position of test tube flat 31, to meet the requirement of subsequent processing.
Automatic pipetting device 9 and slide displacing mechanism are automatically moved by the realization of linear movement module, linear movement module
Including moving left and right device 3 (X-direction), being moved forward and backward device 4 (Y direction) and moving up and down device 5 (Z-direction), energy
Enough realize that automatic pipetting device 9 and slide displacing mechanism are moved along X-axis, Y-axis, Z-direction.
It moves up and down there are two devices 5, one is used to install automatic pipetting device 9, another is for installing slice movement
Device.
It is described to move left and right device 3, be moved forward and backward device 4 and move up and down device 5 using guiding rail mechanism.
In some embodiments, the guiding rail mechanism selects ball screw linear guide.
It need to remove since biological sample is centrifuged the serum that front and back generates, be added according to experiment process progress into test tube 30 in time
Enter reagent, and the biological sample after the completion of centrifugation is dripped on glass slide and requires automatic mobile device 9.
The automatic pipetting device 9 include electric pipettor 8, by electric pipettor 8 realize liquid it is accurate absorption with
Drop is put, and realizes moving up and down for electric pipettor 8 by linear movement module.
Slide displacing mechanism includes sucker 27 and pneumatic mechanism, and the sucker 27 provides adsorption capacity by pneumatic mechanism.
The pneumatic mechanism includes air pump 22, vacuum generator 25, vacuum filter 23, conduit and three-way magnetic valve 26,
The air pump 22 is connected by conduit with sucker 37, and the three-way magnetic valve 26 of control gas flow is equipped on the conduit.
Vacuum generator 25 and vacuum filter 26 are mounted between three-way magnetic valve 26 and air pump 22.
The dye sheet devices 6 include turnover device, dye film trap 14, drop film trap 11, air-dry slot 20, flushed channel 21, slice cabin
13, glass slide cabin 10 and agent delivery device 15.
As Figure 9-Figure 11, dye film trap 14 is distributed in multiple rows of multiple row, and turnover device is installed on 14 top of dye film trap.
The turnover device include turning groove, flip-arm 18 and overturning steering engine 19, the turning groove by flip-arm 18 with
Steering engine 19 is overturn to be connected.
The notch that turning groove opens up is adapted with slice size.
Slice cabin 13 is set to 14 rear side of dye film trap and arranges in multiple rows of multiple row, for storing chromosome slice such as Figure 12 institute
Show.
Glass slide storehouse 10, which is set to, is sliced 13 side of cabin, settable one or more, as shown in figure 13, glass slide storehouse 10
Two sides offer U-type groove.
Multiple row is set on front side of glass slide storehouse 10 and drips film trap 11, can be used for placing glass slide, realize that the drop of sample is put.
It drips to be equipped between film trap 11 and staining trough 14 and air-dries slot 20, flushed channel 21.
It is equipped with water pump in the flushed channel 21, clean water can be sprayed, for rinsing slice.
The air-dried slot 20 configures blower, can blow out dry air, realizes air-drying for slice.
Agent delivery device 15 is equipped on front side of the drop film trap 11, agent delivery device 15 is held including multiple for placing
There is the closed container of different liquids reagent, when needing using liquid, reagent is taken out out of container, is used for experiment.
The closed container connects liquid flowing tube, installs solenoid valve in liquid flowing tube, for adjusting reagent flow, and passes through photoelectricity
Sensor detects the capacity of trickle, and guarantee had not only been able to satisfy experimental measuring requirement, but also reagent can be avoided to volatilize to greatest extent.
Slice after the completion of the application drop piece is stapled in each staining trough 14 by slide displacing mechanism, turnover device
Drive flip-arm 18 that the slice in turning groove perpendicular to operating surface, a part slice is immersed in and is held by overturning steering engine 19
Have in the dye film trap of dyeing liquor.
Through immersion after a period of time, turnover device drives flip-arm 18 to be once again parallel to slice by overturning steering engine 19
Operating surface, then slice is placed into flushed channel 21 and rinses by slide displacing mechanism, and air-dried 20 apoplexy of slot is put into after the completion of rinsing
It is dry.
After completing above-mentioned steps, the slice that dyeing is completed is put into slice cabin 10.
The automatic scanning system 1 is existing for scanning the slice after completing, including microscope, the microscope
Technology, details are not described herein again.
1 installed in front touch screen integrated machine 12 of automatic scanning system configures chromosome image acquisition module, memory module
And analysis module, for analyzing the data after slice scanning.
The application further includes thermostat, for guaranteeing that chromosome analysis process is in stationary temperature.
Thermostat uses existing mechanism, and details are not described herein again.
The foregoing is merely preferred embodiment of the present application, are not intended to limit this application, for the skill of this field
For art personnel, various changes and changes are possible in this application.Within the spirit and principles of this application, made any to repair
Change, equivalent replacement, improvement etc., should be included within the scope of protection of this application.
Claims (10)
1. a kind of microsection manufacture dyeing and scanning integrated machine characterized by comprising
Centrifugal device, internal to install test tube flat, test tube flat is connected with the vibration for being uniformly mixed reagent with biological sample
Evenly mixing device；
Positioning and recognizing device, including the gear indexing mechanism for realizing test tube flat fine rotational and for identification test tube flat position
Color sensor；
Automatic pipetting device, including electric pipettor, the electric pipettor drive its movement by linear movement module；
Slide displacing mechanism is installed on linear movement module side, including the sucker for drawing and placing slice, the sucker
Adsorption capacity is provided by pneumatic mechanism；
Sheet devices are contaminated, including can be realized the dyeing, flushing, air dry operation of slice for driving the turnover device of slicing motion；
Automatic scanning system, for scan, handle through dye piece treated slice.
2. a kind of microsection manufacture dyeing according to claim 1 and scanning integrated machine, which is characterized in that the vibration mixes
Device includes vibrating motor, and the vibrating motor is connected with test tube flat.
3. a kind of microsection manufacture dyeing according to claim 1 and scanning integrated machine, which is characterized in that the fixation and recognition
Device is installed on above centrifugal device, including shell, gear indexing mechanism are installed on enclosure interior and are connected with test tube flat.
4. a kind of microsection manufacture dyeing according to claim 1 and scanning integrated machine, which is characterized in that the linear movement
Module include move left and right device, with move left and right back-and-forth motion device that device is connected, be moved forward and backward device be connected it is upper
Lower mobile device.
5. a kind of microsection manufacture dyeing according to claim 4 and scanning integrated machine, which is characterized in that described to move up and down
There are two devices, is connected respectively with automatic pipetting device, slide displacing mechanism.
6. a kind of microsection manufacture dyeing according to claim 1 and scanning integrated machine, which is characterized in that the pneumatic mechanism
Including air pump, the air pump is connected by conduit with sucker, and the three-way magnetic valve of control gas flow is equipped on the conduit.
7. a kind of microsection manufacture dyeing according to claim 6 and scanning integrated machine, which is characterized in that the threeway electromagnetism
Vacuum generator and vacuum filter are installed between valve and air pump.
8. a kind of microsection manufacture dyeing according to claim 1 and scanning integrated machine, which is characterized in that the dye sheet devices
Including multiple dye film traps, turnover device is installed on above dye film trap comprising multiple turning grooves, the turning groove pass through flip-arm
It is connected with overturning steering engine.
9. a kind of microsection manufacture dyeing according to claim 8 and scanning integrated machine, which is characterized in that the dye film trap side
Face is equipped with drop film trap, air-dries slot, flushed channel, slice cabin, glass slide cabin and agent delivery device.
10. a kind of microsection manufacture dyeing according to claim 9 and scanning integrated machine, which is characterized in that the flushed channel
In be equipped with water pump, the air-dried slot configures blower.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811480003.4A CN109387419A (en) | 2018-12-05 | 2018-12-05 | A kind of dyeing of microsection manufacture and scanning integrated machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811480003.4A CN109387419A (en) | 2018-12-05 | 2018-12-05 | A kind of dyeing of microsection manufacture and scanning integrated machine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109387419A true CN109387419A (en) | 2019-02-26 |
Family
ID=65430229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811480003.4A Pending CN109387419A (en) | 2018-12-05 | 2018-12-05 | A kind of dyeing of microsection manufacture and scanning integrated machine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109387419A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112221725A (en) * | 2020-09-24 | 2021-01-15 | 湖北中医药高等专科学校 | Vacuum test analysis device for clinical laboratory |
| CN112345317A (en) * | 2020-09-09 | 2021-02-09 | 安徽九陆生物科技有限公司 | Liquid-based cell slide scanning and reading mechanism and using method thereof |
| CN113820193A (en) * | 2021-08-05 | 2021-12-21 | 南京市口腔医院 | Device and method for treating oral squamous carcinoma in-vitro tumor tissue specimen and application |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040002415A1 (en) * | 2002-06-28 | 2004-01-01 | Jang Gi Young | Automated centrifuge system |
| CN104884930A (en) * | 2012-11-01 | 2015-09-02 | 莱卡生物系统墨尔本私人有限公司 | A slide transport system |
| CN105890958A (en) * | 2014-11-24 | 2016-08-24 | 王素蓉 | Staining method |
| CN106124280A (en) * | 2016-05-31 | 2016-11-16 | 李琳 | Full-automatic chromosome dyeing device |
| CN106824560A (en) * | 2017-03-14 | 2017-06-13 | 骏实生物科技(上海)有限公司 | A kind of automatic mixing device for centrifugal platform |
| CN106979878A (en) * | 2017-05-09 | 2017-07-25 | 南昌德漫多科技有限公司 | A kind of histopathology sample processing system |
| CN206450486U (en) * | 2016-12-30 | 2017-08-29 | 王海波 | Automatic smear overflow dyeing machine |
| CN208060258U (en) * | 2017-12-29 | 2018-11-06 | 山东仕达思生物产业有限公司 | A kind of full-automatic glass slide smear dyeing machine |
| CN209166961U (en) * | 2018-12-05 | 2019-07-26 | 滨州医学院 | A kind of dyeing of microsection manufacture and scanning integrated machine |
-
2018
- 2018-12-05 CN CN201811480003.4A patent/CN109387419A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040002415A1 (en) * | 2002-06-28 | 2004-01-01 | Jang Gi Young | Automated centrifuge system |
| CN104884930A (en) * | 2012-11-01 | 2015-09-02 | 莱卡生物系统墨尔本私人有限公司 | A slide transport system |
| CN105890958A (en) * | 2014-11-24 | 2016-08-24 | 王素蓉 | Staining method |
| CN106124280A (en) * | 2016-05-31 | 2016-11-16 | 李琳 | Full-automatic chromosome dyeing device |
| CN206450486U (en) * | 2016-12-30 | 2017-08-29 | 王海波 | Automatic smear overflow dyeing machine |
| CN106824560A (en) * | 2017-03-14 | 2017-06-13 | 骏实生物科技(上海)有限公司 | A kind of automatic mixing device for centrifugal platform |
| CN106979878A (en) * | 2017-05-09 | 2017-07-25 | 南昌德漫多科技有限公司 | A kind of histopathology sample processing system |
| CN208060258U (en) * | 2017-12-29 | 2018-11-06 | 山东仕达思生物产业有限公司 | A kind of full-automatic glass slide smear dyeing machine |
| CN209166961U (en) * | 2018-12-05 | 2019-07-26 | 滨州医学院 | A kind of dyeing of microsection manufacture and scanning integrated machine |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112345317A (en) * | 2020-09-09 | 2021-02-09 | 安徽九陆生物科技有限公司 | Liquid-based cell slide scanning and reading mechanism and using method thereof |
| CN112221725A (en) * | 2020-09-24 | 2021-01-15 | 湖北中医药高等专科学校 | Vacuum test analysis device for clinical laboratory |
| CN112221725B (en) * | 2020-09-24 | 2022-04-22 | 湖北中医药高等专科学校 | Vacuum test analysis device for clinical laboratory |
| CN113820193A (en) * | 2021-08-05 | 2021-12-21 | 南京市口腔医院 | Device and method for treating oral squamous carcinoma in-vitro tumor tissue specimen and application |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6532559B2 (en) | Automated histological processing of biological samples and associated techniques | |
| CN105980828B (en) | Staining reagents and other fluids for tissue processing of biological specimens and associated techniques | |
| US11524287B2 (en) | Automatic pipetting device for transferring samples and/or reagents and method for transferring liquid samples and/or reagents | |
| CN105980827B (en) | Thermal management in the context of automated tissue processing of biological specimens and associated techniques | |
| EP3080578B1 (en) | Automated processing systems and methods of thermally processing microscope slides | |
| CN109387419A (en) | A kind of dyeing of microsection manufacture and scanning integrated machine | |
| JP5393608B2 (en) | Automatic analyzer | |
| JP2002071538A (en) | Method and apparatus for dyeing tissue sample arranged on slide glass | |
| CN209166961U (en) | A kind of dyeing of microsection manufacture and scanning integrated machine | |
| US11579053B2 (en) | Specimen processing systems, pipette assemblies and methods for preparing reagents | |
| KR102647051B1 (en) | Apparatus and method for staining organic materials on slides | |
| CN112730000B (en) | Automatic change drop dyeing sealing piece equipment | |
| CN214408321U (en) | Automatic change and drip dyeing mounting equipment | |
| CN112710527B (en) | Automatic dyeing device for biological tissue sample slices | |
| CN214310119U (en) | Sample analyzer | |
| CN214408322U (en) | Automatic drop dyeing mounting equipment with human-computer interaction function | |
| CN112840195B (en) | Sample dyeing method, smear preparation equipment and dyeing liquid combination | |
| CN114689890A (en) | Sample analyzer and method for controlling sample analyzer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |