CN106824560A - A kind of automatic mixing device for centrifugal platform - Google Patents
A kind of automatic mixing device for centrifugal platform Download PDFInfo
- Publication number
- CN106824560A CN106824560A CN201710151573.8A CN201710151573A CN106824560A CN 106824560 A CN106824560 A CN 106824560A CN 201710151573 A CN201710151573 A CN 201710151573A CN 106824560 A CN106824560 A CN 106824560A
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- Prior art keywords
- centrifugal
- transmission mechanism
- centrifuge tube
- mixing device
- automatic mixing
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- 238000002156 mixing Methods 0.000 title claims abstract description 48
- 230000005540 biological transmission Effects 0.000 claims abstract description 40
- 238000005119 centrifugation Methods 0.000 claims abstract description 26
- 238000009987 spinning Methods 0.000 claims abstract description 9
- 230000008520 organization Effects 0.000 claims description 3
- 239000007788 liquid Substances 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 5
- 230000006378 damage Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000009514 concussion Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008450 motivation Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/20—Mixing the contents of independent containers, e.g. test tubes
- B01F31/25—Mixing the contents of independent containers, e.g. test tubes the containers being submitted to a combination of movements other than within a horizontal plane, e.g. rectilinear and pivoting movement
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Centrifugal Separators (AREA)
Abstract
The invention discloses a kind of automatic mixing device for centrifugal platform, including the centrifugation tube fixing mechanism, motion control mechanism and the transmission mechanism that are arranged in the centrifugal channel of centrifugal platform, the centrifugation tube fixing mechanism is used to fix centrifuge tube, it is set not slide, the transmission mechanism is used to drive the centrifuge tube to be swung or spinning motion, and the motion control mechanism can control the motion mode of the transmission mechanism.The present invention centrifugal platform is combined with automatic mixing device, will centrifugation module with mixing it is module integrated together with, make centrifugation, mixing step completed in same equipment, enormously simplify human users' step, save the time.
Description
Technical field
The present invention relates to a kind of automatic mixing device for centrifugal platform.
Background technology
Experimental technique field and medical instruments field will often use centrifuge, and the step of experiment is more, centrifugation, mixing
Step would generally be interted to be carried out, and traditional centrifugation, is mixed step and is needed manual operation, is bothered very much, in particular for several steps from
The situation of heart step, therefore automatic mixing device is set in centrifugal platform can simplify experiment flow, reduce person works' amount and
Error rate.
Liquid blending mode common at present includes stirring, suction and concussion etc., but these blending manners all relatively swash
Strong, in some experiments for being related to cell extraction, these blending manners easily damage aim cell, therefore, people in the art
Member is devoted to developing a kind of good automatic mixing mode of the small, Blending Efficiency of Blending of damage, and further by these blending manners and centrifugation
Platform integration is together.
The content of the invention
In view of the drawbacks described above of prior art, the invention provides a kind of automatic mixing device for centrifugal platform,
Described device includes the centrifugation tube fixing mechanism, motion control mechanism and the driver that are arranged in the centrifugal channel of centrifugal platform
Structure, the centrifugation tube fixing mechanism is used to fix centrifuge tube, it is not slid, the transmission mechanism be used to driving it is described from
Heart pipe is swung or spinning motion, and the motion control mechanism can control the motion mode of the transmission mechanism.
" centrifugal channel " of the present invention refers to the hole position of placement centrifuge tube in centrifuge.
Further, the motion control mechanism includes micromachine.
In the preferred embodiment of the present invention, the transmission mechanism is arranged at the top of the centrifugal channel,
The centrifugation tube fixing mechanism is arranged in the transmission mechanism, and such as internal diameter is equal or slightly larger than centrifuge tube external diameter and inner surface
Coarse cylindrical hole, centrifuge tube is arranged in the through hole, and relative displacement will not occur, and the transmission mechanism can receive the fortune
Dynamic controlling organization control swings, so as to drive centrifuge tube to swing together.The transmission mechanism and the centrifuge tube fix machine
Structure can also merge the cylinder-like structure for being designed as backing, and the centrifuge tube can be directly placed into the structure, can both be driven
The motion of centrifuge tube can be such that centrifuge tube does not slide again.
Another situation is that the transmission mechanism is arranged at the bottom of the centrifugal channel, the motion control mechanism
It is can control to swing, but the centrifugation tube fixing mechanism is arranged at the top of the centrifugal channel, can be still interior
Footpath is equal or slightly larger than the cylindrical hole of centrifuge tube external diameter and rough inner surface, the fixed mechanism be swingably arranged on from
The top of heart passage, but it does not control directly by motion control mechanism, but the transmission mechanism in bottom drive it is described from
Heart pipe passively swings together when swinging, and transmission mechanism allows the mode that centrifuge tube swings to have various, such as passes through forced contact
Bring it about swing.
In another preferred embodiment of the invention, the transmission mechanism is arranged at the bottom of the centrifugal channel
Portion, the centrifugation tube fixing mechanism is arranged at the top of the transmission mechanism, centrifuge tube can be fixed with the transmission mechanism
Together, the motion control mechanism can control spinning motion of the transmission mechanism generation around centrifugal channel center longitudinal axis, from
And drive the centrifuge tube that spinning motion occurs together.Preferably, the centrifugation tube fixing mechanism is mechanical gripper.
In this kind of implementation method, the transmission mechanism be preferably can oscilaltion, when centrifugal platform carries out centrifugally operated
When, the transmission mechanism is down to bottom, and the rotation of centrifuge tube is not influenceed, when centrifugal platform mix operation, the transmission
Mechanism rises to fixed mechanism and can be fixedly connected the position of centrifuge tube, so that transmission mechanism can drive centrifuge tube to move.
Preferably, in the present embodiment, the automatic mixing device for centrifugal platform also includes centrifuge tube stop
Mechanism, the mechanism can be arranged on the optional position in centrifugal channel, be stopped by contacting generation frictional force with centrifuge tube
The rotation of centrifuge tube.
Further, to coordinate this kind of automatic mixing device, branch is additionally provided with the top of the centrifugal platform centrifugal channel
Support, and at the opening of the centrifuge tube/the tube wall outside on top is provided with projection, the projection is engaged with support frame as described above,
When mixing step is not carried out for preventing centrifuge tube from dropping because of the decline of transmission mechanism, while should when mixing step is carried out
Support frame also will not produce resistance to the spinning motion of centrifuge tube.
Further, in order that the effect of rotation mixing is more preferable, the present invention also provides a kind of centrifuge tube with interior burr,
Its principle is to increase the friction between liquid and centrifugation tube wall, so that liquid follows the rotation of centrifuge tube to move together, it is described
The interior burr of centrifuge tube is preferably spirality line.
" top " of the present invention refers to preferably 2/3, part more than height in the part 1/2；" bottom " refers at this
Part 1/2, preferably 1/3, the part below height.
Further, present invention also offers the centrifuge with foregoing automatic mixing device.
The device have the advantages that：The present invention centrifugal platform is combined with automatic mixing device, will be centrifuged module and
Mixing is module integrated together, centrifugation, mixing step is completed in same equipment, enormously simplify human users' step,
The time is saved, human error is also reduced, the blending manner that the present invention is used in addition includes swinging and rotation, both modes
All very light and slow, particularly rotation and the combination of centrifuge tube burr compared with traditional blending manner, can largely mitigate
Damage to cell, and more excellent Blending Efficiency of Blending can be obtained.
Brief description of the drawings
Fig. 1 is the side structure schematic view of a preferred embodiment of the invention；
Fig. 2 is the centrifugal head structural representation of a preferred embodiment of the invention；
Fig. 3 is the structural representation of centrifuge tube in a preferred embodiment of the invention；
Fig. 4 is the centrifugal head structural representation of another preferred embodiment of the invention.
Specific embodiment
The present invention is described in further detail with embodiment below in conjunction with the accompanying drawings, but those skilled in the art are according to following
The replacement of concrete scheme, conversion or combination are both contained within protection scope of the present invention in embodiment.
Embodiment 1
As depicted in figs. 1 and 2, the evenly mixing device of the present embodiment is combined with centrifugal platform, the centrifugal platform turn
Head includes 12 (6 groups) centrifugal channels 1, and centrifuge tube support frame 2 is provided with the top of the centrifugal channel, is used in the present embodiment
Raised 31 are provided with the opening of centrifuge tube 3 can be held on support frame 2, shown evenly mixing device include being arranged on centrifugal platform from
Centrifugation tube fixing mechanism 4, motion control mechanism (not shown) and transmission mechanism 5 in heart passage 1, wherein centrifuge tube are fixed
Mechanism 4 is mechanical gripper, and when being mixed, the mechanical gripper can firmly catch centrifuge tube, and the mechanical gripper and shaft-like biography
Motivation structure 5 is fixedly connected, and the bottom of the fixed mechanism 5 is also associated with motion control mechanism, and the motion control mechanism is by miniature
Motor control can make transmission mechanism 5 that the spinning motion around its center longitudinal axis (shown in dotted line) occurs, so as to drive centrifuge tube 3 together
Rotation.
Further, shown centrifugation tube fixing mechanism 4 can be lifted with the lifting of transmission mechanism 5, when centrifugation step is entered,
The manipulator that tube fixing mechanism 4 is centrifuged opens and drops to setting position, and centrifugal platform starts to rotate centrifugation；Walked in mixing when entering
When rapid, with centrifuge tube be aligned manipulator, then motion control mechanism control by centrifugal platform energy automatic identification position, searching position
Transmission mechanism processed 5 rises to correct position under software, and manipulator catches centrifuge tube, and starts to be rotated by setting speed,
Carry out mixing operation.
Additionally, the automatic mixing device of the present embodiment also includes being arranged on the centrifuge tube stop mechanism 6 on centrifugal channel top,
When centrifuge tube carries out mixing rotation, the stop mechanism 6 is separated with centrifuge tube, at the end of mixing, the stop mechanism 6 and centrifuge tube
Contact, by frictional force come the rotation of speed reducing centrifugal pipe until stopping.
Embodiment 2
In the present embodiment provide for this rotation type of embodiment 1 evenly mixing device special centrifuge tube, it is shown from
Heart pipe as shown in figure 3, more whole pipe shaft outwardly convex 31 at the opening of the centrifuge tube, for being held on 2 on support frame, and pipe
Inwall has inwardly protruded helical structure lines 32, and so when centrifuge tube occurs rotation, the lines can make the liquid in pipe
There is screw along the direction of helix, so as to preferably mix liquid, the form of the lines is not unique, as long as having Inner
Burr road just can drive liquid motion.
Embodiment 3
In the present embodiment, the rotary head structure of the centrifugal platform also can be with similar (Fig. 4) in embodiment 1, but centrifuge tube
Fixed mechanism 4 ' is but arranged on the hanging basket 7 of centrifugal platform, is the two pieces of clamp systems that can clamp centrifuge tube (with supporting mechanism knot
Structure is identical, but internal diameter is smaller, and rough inner surface).The hanging basket 7 also serves as transmission mechanism simultaneously, can be swung around fixing axle, and receive
To the control of motion control mechanism, the effect for mixing is swung so as to reach centrifuge tube.But the swing of hanging basket 7 in the present embodiment
Can not be directly by motion control mechanism control, but by the transmission mechanism control of centrifugal channel bottom, the transmission mechanism
Centrifuge tube and hanging basket is set passively to swing by the forced contact with centrifugation bottom of the tube, and transmission mechanism is controlled by motion control mechanism
System.Additionally, the fixed mechanism in the present embodiment can also be internal diameter equal or slightly larger than centrifuge tube external diameter and rough inner surface
Cylindrical hole, hanging basket can also be tubular construction with the end.
Preferred embodiment of the invention described in detail above.It should be appreciated that one of ordinary skill in the art without
Need creative work just can make many modifications and variations with design of the invention.Therefore, all technologies in the art
Personnel are available by logical analysis, reasoning, or a limited experiment on the basis of existing technology under this invention's idea
Technical scheme, all should be in the protection domain being defined in the patent claims.
Claims (10)
1. a kind of automatic mixing device for centrifugal platform, it is characterised in that including being arranged in the centrifugal channel of centrifugal platform
Centrifugation tube fixing mechanism, motion control mechanism and transmission mechanism, the centrifugation tube fixing mechanism is used to fix centrifuge tube, makes it
Do not slide, the transmission mechanism is used to drive the centrifuge tube to be swung or spinning motion, the motion control mechanism
Can control the motion mode of the transmission mechanism.
2. the automatic mixing device of centrifugal platform is used for as claimed in claim 1, it is characterised in that the transmission mechanism is set
The top of the centrifugal channel is placed in, the centrifugation tube fixing mechanism is arranged in the transmission mechanism.
3. the automatic mixing device of centrifugal platform is used for as claimed in claim 2, it is characterised in that the centrifuge tube fixes machine
Structure is equal or slightly larger than the cylindrical hole of centrifuge tube external diameter and rough inner surface for internal diameter, and the transmission mechanism can receive the fortune
Dynamic controlling organization control swings, so as to drive the centrifuge tube to swing together.
4. the automatic mixing device of centrifugal platform is used for as claimed in claim 2, it is characterised in that the transmission mechanism and institute
State the cylinder-like structure that centrifugation tube fixing mechanism merges into backing.
5. the automatic mixing device of centrifugal platform is used for as claimed in claim 1, it is characterised in that the transmission mechanism is set
The bottom of the centrifugal channel is placed in, the motion control mechanism can control it and swing, the centrifugation tube fixing mechanism quilt
It is arranged at the top of the centrifugal channel.
6. the automatic mixing device of centrifugal platform is used for as claimed in claim 1, it is characterised in that the transmission mechanism is set
The bottom of the centrifugal channel is placed in, the centrifugation tube fixing mechanism is arranged at the top of the transmission mechanism, the motion
Controlling organization can control spinning motion of the transmission mechanism generation around centrifugal channel center longitudinal axis, so as to drive the centrifuge tube
There is spinning motion together.
7. the automatic mixing device of centrifugal platform is used for as claimed in claim 6, it is characterised in that the centrifuge tube fixes machine
Structure is mechanical gripper.
8. the automatic mixing device of centrifugal platform is used for as claimed in claim 6, it is characterised in that also including centrifuge tube stop
Mechanism.
9. centrifuge of a kind of band just like the automatic mixing device for centrifugal platform described in claim any one of 1-8.
10. centrifuge as claimed in claim 9, it is characterised in that be additionally provided with branch on the top of the centrifuge passage
Support, and at the opening of the centrifuge tube/the tube wall outside on top is provided with projection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710151573.8A CN106824560A (en) | 2017-03-14 | 2017-03-14 | A kind of automatic mixing device for centrifugal platform |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710151573.8A CN106824560A (en) | 2017-03-14 | 2017-03-14 | A kind of automatic mixing device for centrifugal platform |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106824560A true CN106824560A (en) | 2017-06-13 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710151573.8A Pending CN106824560A (en) | 2017-03-14 | 2017-03-14 | A kind of automatic mixing device for centrifugal platform |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108014929A (en) * | 2018-01-17 | 2018-05-11 | 山东建筑大学 | A kind of combined type medical test solution centrifugal device |
| CN109387419A (en) * | 2018-12-05 | 2019-02-26 | 滨州医学院 | A kind of dyeing of microsection manufacture and scanning integrated machine |
| CN110665654A (en) * | 2019-09-29 | 2020-01-10 | 深圳赛动生物自动化有限公司 | Centrifugal pipe clamping and moving mechanism and working method thereof |
| CN110665651A (en) * | 2019-10-14 | 2020-01-10 | 山东中医药大学附属医院 | Automatic draw type cell experiment centrifuge |
| CN111690775A (en) * | 2020-06-24 | 2020-09-22 | 哈尔滨元亨生物药业有限公司 | African swine fever virus fluorescence PCR rapid detection kit |
| CN112457979A (en) * | 2020-11-19 | 2021-03-09 | 江西迈柯菲生物医药科技有限公司 | Double-cylinder centrifugal large-scale suspension type cell culture device |
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| CN105388311A (en) * | 2015-12-21 | 2016-03-09 | 艾康生物技术(杭州)有限公司 | Full-automatic chemiluminescence immunoassay instrument |
| CN105598110A (en) * | 2014-10-27 | 2016-05-25 | 朱丹 | Automatic cleaning method with solid-liquid separation |
| CN205301341U (en) * | 2015-12-23 | 2016-06-08 | 深圳雷杜生命科学股份有限公司 | Anticollision formula self - cleaning , mixing and separator |
| CN105880041A (en) * | 2016-05-11 | 2016-08-24 | 刘志华 | Mechanism for simultaneously realizing functions of blending and centrifuging reagent |
| CN205528717U (en) * | 2016-04-19 | 2016-08-31 | 新疆大学 | RNA extraction element |
| CN106999955A (en) * | 2014-07-29 | 2017-08-01 | 约阿希姆·格斯特尔 | For the component for the sample for preparing to be largely used to analysis method |
| CN206587918U (en) * | 2017-03-14 | 2017-10-27 | 骏实生物科技(上海)有限公司 | A kind of automatic mixing device for centrifugal platform |
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| US5199937A (en) * | 1989-08-24 | 1993-04-06 | Kurashiki Boseki Kabushiki Kaisha | Centrifugal separator |
| CN102095625A (en) * | 2011-01-27 | 2011-06-15 | 桂林优利特医疗电子有限公司 | Blending device of blood cell analyzer |
| CN103041933A (en) * | 2013-01-22 | 2013-04-17 | 中国检验检疫科学研究院 | Portable vortex and centrifugation integrated machine |
| CN203275173U (en) * | 2013-04-16 | 2013-11-06 | 深圳迈瑞生物医疗电子股份有限公司 | Reaction liquid mixing device and chemical analysis meter |
| CN203886684U (en) * | 2014-06-10 | 2014-10-22 | 苏州培英实验设备有限公司 | Centrifuging and vibration mixing integrated machine |
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| CN105388311A (en) * | 2015-12-21 | 2016-03-09 | 艾康生物技术(杭州)有限公司 | Full-automatic chemiluminescence immunoassay instrument |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108014929A (en) * | 2018-01-17 | 2018-05-11 | 山东建筑大学 | A kind of combined type medical test solution centrifugal device |
| CN108014929B (en) * | 2018-01-17 | 2023-09-01 | 山东建筑大学 | Combined medical test solution centrifugal device |
| CN109387419A (en) * | 2018-12-05 | 2019-02-26 | 滨州医学院 | A kind of dyeing of microsection manufacture and scanning integrated machine |
| CN109387419B (en) * | 2018-12-05 | 2024-06-28 | 滨州医学院 | Slice manufacturing, dyeing and scanning integrated machine |
| CN110665654A (en) * | 2019-09-29 | 2020-01-10 | 深圳赛动生物自动化有限公司 | Centrifugal pipe clamping and moving mechanism and working method thereof |
| CN110665651A (en) * | 2019-10-14 | 2020-01-10 | 山东中医药大学附属医院 | Automatic draw type cell experiment centrifuge |
| CN111690775A (en) * | 2020-06-24 | 2020-09-22 | 哈尔滨元亨生物药业有限公司 | African swine fever virus fluorescence PCR rapid detection kit |
| CN112457979A (en) * | 2020-11-19 | 2021-03-09 | 江西迈柯菲生物医药科技有限公司 | Double-cylinder centrifugal large-scale suspension type cell culture device |
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Application publication date: 20170613 |