CN109381657A - It is a kind of for treating the Chinese medicine of heatstroke - Google Patents

It is a kind of for treating the Chinese medicine of heatstroke Download PDF

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Publication number
CN109381657A
CN109381657A CN201710653671.1A CN201710653671A CN109381657A CN 109381657 A CN109381657 A CN 109381657A CN 201710653671 A CN201710653671 A CN 201710653671A CN 109381657 A CN109381657 A CN 109381657A
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Prior art keywords
heatstroke
parts
heat
treating
chinese medicine
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CN201710653671.1A
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Chinese (zh)
Inventor
路云香
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Zibo Mingtong Environmental Protection Technology Research and Development Co Ltd
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Zibo Mingtong Environmental Protection Technology Research and Development Co Ltd
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Priority to CN201710653671.1A priority Critical patent/CN109381657A/en
Publication of CN109381657A publication Critical patent/CN109381657A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532Agastache, e.g. giant hyssop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to a kind of for treating the Chinese medicine of heatstroke, it is prepared by the raw medicinal material of following weight proportion: 9 parts of wrinkled giant hyssop, 9 parts of Radix Curcumae, 8 parts of cape jasmine, 6 parts of Radix Ophiopogonis.Clinical experiments have proved that the present invention can safely and effectively treat heatstroke.

Description

It is a kind of for treating the Chinese medicine of heatstroke
Technical field
The present invention relates to a kind of Chinese medicines, and in particular to a kind of for treating the Chinese medicine of heatstroke.
Background technique
Influence due to high fever to body so that heat-regulating centers obstacle, sweat gland functional failure and water/electrolyte disturbance, Cause body multisystem that a series of syndrome of pathological changes occurs.
Hot environment is adapted to insufficient be the main reason for causing a disease.Atmospheric temperature increase (> 32 DEG C), humidity it is larger (> 60%) it and in calm environment, works long hours or strong physical work, and when without abundant measures of heat control, lacks to high fever ring Thermoplegia easily occurs for border accommodator.Easy hair factor include: 1. environment temperature it is excessively high: human body obtains heat by external environment.2. people Body heat production increases: being such as engaged in heavy physical labour, fever, hyperthyroidism and applies some drugs (amphetamine).3. radiating Obstacle: such as humidity is larger, obesity or penetrates the undesirable clothes of gas.4. sweat gland dysfunction: seeing systemic sclerosis, wide The patients such as cicatrization or congenital sweat gland deficiency disease after general skin burn.
It is much more clinical to show as the symptoms such as profuse sweating, thirsty, out of strength, dizzy, uncomfortable in chest, seriously have often high fever, skin burns, The performances such as Nausea and vomiting, blood pressure are begun to decline, arteries and veins turn is counted accurately, fainted, going into a coma, spasm.It can be divided according to the different manifestations of patient For 3 seed types: premonitory heatstroke, mild heat stroke, severe heatstroke.
Medicinal material present Research involved in the present invention is as follows:
Wrinkled giant hyssop [source] is the herb of Lamiaceae plant Pogostemon cablin or wrinkled giant hyssop.Harvesting when Pogostemon cablin grows in great numbers between 6~July, Hainan Region receives 2 times every year, in 5~June, in 9~October, removes fibrous root, soil the 2nd time the 1st time, shines 2~3 days, stacks, bored It is shone again after 2 days, then bored, such heap shines until dry.The 1st harvesting when blooming for 6~July of wrinkled giant hyssop, the 2nd time in October.After adopting It dries or dries in the shade.Old stem person, medicinal material name " leaves of pulse plants stalk " is applied alone.[processing] wrinkled giant hyssop: picking impurity, undesirable root and old stem is removed, first by leaf Take and separately put, stem is moisturized with water, and dissection is dried, then with leaf and even.Leaves of pulse plants stalk: old stem is taken, water logging moisturizes, and slice dries.[property Taste] pungent, tepor.[channel tropism] enters lung, spleen, stomach meridian.[major function] fast gas, and in, ward off dirty, clearing damp.Cure cold summer-heat and damp, trembles with fear Heat, headache, chest gastral cavity ruffian, vomiting and diarrhea, malaria, dysentery, halitosis.[usage and dosage] 5~15g.
Radix Curcumae [source] this product is zingiberaceous plant RADIX CURCUMAE Curcuma wenyujin Y. H. Chen et C. Ling, turmeric Curcuma longa L., Guangxi zedoary Curcuma kwangsiensis S. G. Lee et C. F. The dried root of Liang or zedoary Curcuma phaeocaulis Val..The above two practise title " RADIX CURCUMAE " and " yellow silk respectively Radix Curcumae ", remaining is practised by character difference claims " Gui Yujin " or " green silk Radix Curcumae ".It is excavated after winter cauline leaf is withered, removes silt and thin Root is steamed or boiled to the saturating heart, dry.[processing] is cleaned, and is moisturized, shave, dry;Or cleaning, drying, it smashes.[nature and flavor] pungent, Hardship is trembled with fear.[channel tropism] returns liver, the heart, lung channel.[major function] regulating qi to disperse stagnation, heart fire-clearing upset-relieving, normalizing gallbladder to cure jaundice.For amenorrhea and algomenorrhea, Chest and abdomen swelling and pain, shouting pain, pyreticosis coma, epilepsy are gone mad, jaundice and reddish urine.[usage and dosage] 3~9g.[storage] sets dry place, prevents Moth.
Cape jasmine [source] this product is the drying and ripening fruit of madder wort cape jasmine Gardenia jasminoides Ellis Real, root can also be used as medicine.Fruit maturation in 9~November harvests when being in reddish yellow, removes carpopodium and impurity, steams supreme vapour or set boiling It slightly scalds, takes out in water, it is dry.The excavation of root summer and autumn, cleans and dries.[processing] cape jasmine: impurity is removed, is pulverized.[nature and flavor] are bitter, It is cold.[channel tropism] return heart, lung, tri-jiao channel.[major function] purging intense heat relieving restlessness, reducing fever and causing diuresis, removing pattogenic heat from the blood and toxic material from the body.It is yellow for Vexed Subcutaneous ulcer urinates red, blood strangury and dry pain, blood-head tells nosebleed, red eye, swell pain, pathogenic fire,toxin and furuncles;Bruise pain is controlled outside.[usage and dosage] 6~9g.[storage Hiding] it sets at aeration-drying.
Radix Ophiopogonis [source] this product is liliaceous plant Radix Ophiopogonis (dwarf lilyturf) Ophiopogon japonicus (Thunb.) Ker-Gawl. dried root.Summer excavation, cleans, is exposed to the sun, banks up repeatedly, until doing very likely, removes fibrous root, dry.[big gun System] impurity is removed, it cleans, moisturizes, draw down, it is dry.[nature and flavor] are sweet, and slight bitter is slightly cold.[channel tropism] return heart, lung, stomach meridian.[function Can cure mainly] nourishing Yin and promoting production of body fluid, moistening lung and clearing away the heart-fire.For dryness of the lung dry cough.Tuberculosis cough, injury thirst, vexed insomnia, Heat Diabetes, intestines Dry constipation;Pharyngeal diphtheria.[usage and dosage] 6~12g.[storage] is set at shady and cool drying, moisture-proof.
Summary of the invention
The present invention is intended to provide it is a kind of for treating the Chinese medicine of heatstroke, by selecting suitable medicinal material and its proportion, reach Safely and effectively cure the purpose of heatstroke.
In order to achieve the above object, the invention adopts the following technical scheme:
It is a kind of for treating the Chinese medicine of heatstroke, which is characterized in that it is prepared by the raw medicinal material of following weight proportion: the leaves of pulse plants Fragrant 9 parts, 9 parts of Radix Curcumae, 8 parts of cape jasmine, 6 parts of Radix Ophiopogonis.
Inventor thinks heatstroke category traditional Chinese medicine " heat is fainted " scope, and summer-heat being a kind of YANG pathogen, property is hot, and interior strongly fragrantization is fiery therefore generates heat, It burns and steams human body, sweat is the liquid of the heart, and The heart controls mental activities, and sweat, which is crossed, to be let out, and damages the motive, and divine coma occurs in patient therefore heat is fainted;Outside summer-heat and damp Violate, wet mutual knot in exopathogen, ascending or descending movement of vital Qi is unbalance, lung do not rise then breathe clearly it is unfavorable, kidney do not drop it is turbid then can hypourocrinia, the stagnation of the circulation of vital energy then blood The stasis of blood, the then bleeding of hemostasis extravasation of blood.And hot summer weather disease and evil is cruel, the progress of disease is rapid, normal diameter popularity point, if cannot timely removing summer-heat, most easy entry It seeks into blood, straight middle pericardium, or has and go deep into Liver Channel and see coma, convulsion and faint.With clearing summer-heat and tonifying qi, inducing resuscitation of having one's ideas straightened out is basic for Chinese traditional treatment Principle.Wrinkled giant hyssop removing summer-heat in side, Radix Curcumae clearing away the heart fire and tranquillizing, the heat of clear three coke of cape jasmine, Radix Ophiopogonis, nourishing yin and clearing heat, nourishing generate fluid.Mainly The effect of sharing, playing driving away summer heat clearing heat and promoting fluid altogether, therefore assemble we.
The beneficial effects of the present invention will now be described with reference to clinical experimental data:
1, general information
Heatstroke patient 80 are collected in October, -2013 in May, 2012, is randomly divided into 2 groups.Observation group 40, wherein male 28, It is female 12, the age 31-61 years old, 49.5 years old average, it is the course of disease 0.5-19 hours, 6.5 hours average;Control group male 26, female 14, It is age 32-60 years old, 48 years old average, it is the course of disease 0.5-21 hours, 5.5 hours average.Two groups of Genders, age, courses of disease are without statistics Difference is learned, P > 0.05. is shown in Table 1.
2, observation index
The curative effect of two groups of patients treatment is observed, and two groups of high thermal endurances of observation, heating continuing time, symptom and sign restore Time and complications.
3, criterion of therapeutical effect
Cure: patient clinical symptom and positive sign disappear substantially, and body temperature restores normally completely, without repeatedly;It improves: Huan Zhelin Bed sings and symptoms mitigate, and fever mitigates;Invalid: without improving or aggravating, fever does not mitigate or has repeatedly for clinical symptoms and sign. Total effective rate (%)=(healing+improvement)/total number of cases × 100%.
4, treatment method
Control group: Sheng Mai Injection Combining chlorpromazine injection, injection uses to specifications.Treatment 3 days.
5, result
(1) two group of Clinical efficacy comparison is shown in Table 2.Observation group's total effective rate is apparently higher than control group (P < 0.05).
(2) two groups of patient clinical symptoms and positive sign extinction time compare, and are shown in Table 3.The high thermal endurance of observation group, hair Thermal endurance and symptom and sign recovery time are considerably less than control group (P < 0.05).
Complication situation occurs when (3) two groups of patient's treatments
There is 1 renal insufficiency, 1 DIC, complication rate 5.0% in observation group;And control group has 3 kidney functions Can not be complete, 2 DIC and 2 pulmonary edema phenomenons.Complication rate is 17.5%.Two groups of differences have statistical significance (P < 0.05 ).Two groups of patients occur without death.
As it can be seen that drug produced by the present invention can safely and effectively treat heatstroke, there is promotional value.
Specific embodiment
In order to better understand and implement the present invention, the present invention is further illustrated combined with specific embodiments below.
Specific embodiment 1
Weigh: wrinkled giant hyssop 9g, Radix Curcumae 9g, cape jasmine 8g, Radix Ophiopogonis 6g add 8 times of amount water, decoct 1.5 hours, filtering;Filter residue adds 6 times of amounts Water decocts 1 hour, filtering;Merging filtrate is concentrated into 120 grams to get the decoction for meeting one day dosage of normal adult.
For treating heatstroke.Oral, every bu is taken three times in the morning, afternoon and evening.
Specific embodiment 2
Weigh: wrinkled giant hyssop 9g, Radix Curcumae 9g, cape jasmine 8g, Radix Ophiopogonis 6g add 10 times of amount water, decoct 2 hours, filtering;Filter residue adds 8 times of amount water, It decocts 1.5 hours, filtering;Merging filtrate is concentrated, dry, packs to get the powder for meeting one day dosage of normal adult.
For treating heatstroke.It is oral, daily once.
Specific embodiment 3
Weigh: wrinkled giant hyssop 9g, Radix Curcumae 9g, cape jasmine 8g, Radix Ophiopogonis 6g add 6 times of amount water, decoct 3 times, decoct 1 hour every time, merge and decoct Liquid is concentrated, dry, is packed into capsule shells to get the capsule for meeting one day dosage of normal adult.
For treating heatstroke.Oral, every bu is taken twice sooner or later.

Claims (1)

1. a kind of for treating the Chinese medicine of heatstroke, which is characterized in that it is prepared by the raw medicinal material of following weight proportion: 9 parts of wrinkled giant hyssop, 9 parts of Radix Curcumae, 8 parts of cape jasmine, 6 parts of Radix Ophiopogonis.
CN201710653671.1A 2017-08-03 2017-08-03 It is a kind of for treating the Chinese medicine of heatstroke Withdrawn CN109381657A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710653671.1A CN109381657A (en) 2017-08-03 2017-08-03 It is a kind of for treating the Chinese medicine of heatstroke

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710653671.1A CN109381657A (en) 2017-08-03 2017-08-03 It is a kind of for treating the Chinese medicine of heatstroke

Publications (1)

Publication Number Publication Date
CN109381657A true CN109381657A (en) 2019-02-26

Family

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Application Number Title Priority Date Filing Date
CN201710653671.1A Withdrawn CN109381657A (en) 2017-08-03 2017-08-03 It is a kind of for treating the Chinese medicine of heatstroke

Country Status (1)

Country Link
CN (1) CN109381657A (en)

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Application publication date: 20190226

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