CN109363725A - The acquisition device of suction type liquid sample - Google Patents
The acquisition device of suction type liquid sample Download PDFInfo
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- CN109363725A CN109363725A CN201811262140.0A CN201811262140A CN109363725A CN 109363725 A CN109363725 A CN 109363725A CN 201811262140 A CN201811262140 A CN 201811262140A CN 109363725 A CN109363725 A CN 109363725A
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- storage pipe
- liquid storage
- acquisition device
- penetrating member
- diversion
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
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Abstract
The present invention provides a kind of acquisition devices of suction type liquid sample, comprising: liquid storage pipe, with seal cavity, the air pressure of seal cavity is negative pressure；Diversion tube is connected to the seal cavity of liquid storage pipe, and has directed fluid inlet, diversion outlet and the valve being arranged between directed fluid inlet and diversion outlet, and valve controls the connection and closing of directed fluid inlet and diversion outlet；And penetrating member, it is used to pierce through organizer, and be connected to the diversion outlet of diversion tube.In the present invention, doctor etc. can be easily and safely by penetrating member to organizer (such as vitreum of eyes etc.) automatic collection liquid sample, and the liquid sample for being stored in liquid storage pipe directly easily can be carried out subsequent detection.
Description
Technical field
The present invention relates to medical instruments field, in particular to a kind of acquisition device of suction type liquid sample.
Background technique
In medical research, organize intracorporal liquid sample that there is important clinic and scientific research value.Such as ophthalmology
In common clinical samples, the liquid such as vitreous humor and aqueous humor sample examines the cause of disease of vitreoretinal diseases and uveitis
Disconnected, treatment guidance and glaucoma drop intraocular pressure etc. have extremely important clinical and scientific research value.Therefore, it effectively acquires and saves
Liquid sample is also link important in the therapeutic process such as clinical operation.
For the liquid sample in such as ophthalmology, puncture and aspiration once becomes the main side for obtaining liquid sample
Method, but since this method has higher requirement to the operation skill of doctor and acquisition position, and the operating process of tapping can
Control property is poor, and doctor needs manually to extract liquid sample from organizer out.Currently, common ophthalmology liquid methods of sample collection is deposited
In following problem: (1) the intraocular liquid specimen amount that can be acquired is less, when acquiring aqueous humor such as puncture of anterior chamber, in order to obtain sufficient amount
Sample must repeatedly press eyeball, be easy to cause complication；(2) using syringe as the acquisition device of liquid sample, but
It is that this method needs doctor's both hands while operating, and controllability is poor, easily occurs aspirating too quickly and causing operation simultaneously
Send out disease；(3) sample being not easy that storage stays sample to take at syringe needle position loses much again；(4) sample acquired on operating table
The process of unloading storage to liquid storage pipe is various again afterwards, increases the workload for taking sample doctor；(5) in addition to Vitrectomy can obtain
Take more vitreous humor, the still method without acquisition vitreous humor minimally invasive well.
Summary of the invention
The present invention in view of the above-mentioned prior art situation and complete, its purpose is to provide a kind of easy to operate and safe
The acquisition device of reliable suction type liquid sample.
For this purpose, the present invention provides a kind of acquisition devices of suction type liquid sample, comprising: liquid storage pipe has sealing
Cavity, the air pressure of the seal cavity are negative pressure；Diversion tube is connected to the seal cavity of the liquid storage pipe, and is had and led
Inflow entrance, diversion outlet and the valve being arranged between the directed fluid inlet and the diversion outlet, the valve control institute
State the connection and closing of directed fluid inlet Yu the diversion outlet；And penetrating member, be used to pierce through organizer, and with it is described
The directed fluid inlet of diversion tube is connected to.
In the present invention, the operators such as doctor, nurse or other professionals can be conveniently by penetrating member pair
Organizer's (such as anterior chamber or vitreum etc. of eyes) will can easily be acquired by negative pressure automatic collection liquid sample
To the liquid sample for being stored in liquid storage pipe directly carry out subsequent detection, especially suitable in ophthalmology to aqueous humor and vitreous humor
Acquisition.
In addition, the liquid storage pipe is removably connect with the diversion tube in acquisition device according to the present invention.
It finishes to the liquid collection of specimens of liquid storage pipe, is separately separated liquid storage pipe with can be convenient as a result, directly carry out subsequent detection
Step.
In addition, the valve can be the machinery valve of push type in acquisition device according to the present invention.As a result,
The operators such as doctor can be facilitated to operate the valve of diversion tube, to easily control the acquisition of liquid sample.
In addition, the liquid sample can be intraocular vitreous humor in acquisition device according to the present invention.At this
In the case of kind, easily intraocular vitreous humor can be carried out by negative pressure (being lower than intraocular pressure) characteristic in liquid storage pipe automatic
Acquisition.
In addition, in the penetrating member, restricted penetration depth can be set in acquisition device according to the present invention
Position-limit mechanism.Thereby, it is possible to more accurately control the puncture position of penetrating member, the reliability of operation is improved.
In addition, skid resistance strip can be set in the outer surface of liquid storage pipe in acquisition device according to the present invention.By
This, can facilitate the operators such as doctor to remove liquid storage pipe.
In addition, liquid storage pipe can be transparent tube body in acquisition device according to the present invention.Thereby, it is possible to convenient
The operators such as doctor observe the acquisition situation of the liquid sample of liquid storage pipe in real time.
In addition, in liquid storage pipe, scale can be set in acquisition device according to the present invention.Doctor etc. grasps as a result,
The collection capacity of liquid sample can be learnt in real time by making personnel.
In addition, further including the set for being removably covered in the penetrating member in acquisition device according to the present invention
Lid.Thereby, it is possible to ensure that acquisition device is in sealing state, and penetrating member is avoided to accidentally injure operator.
In addition, penetrating member can be needle tubing in acquisition device according to the present invention.Thereby, it is possible to facilitate doctor
Equal operators pierce through the acquisition that organizer carries out liquid sample.
In accordance with the invention it is possible to provide a kind of acquisition dress of suction type liquid sample that can be easy to operate and safe and reliable
It sets.
Detailed description of the invention
Fig. 1 is to show the schematic diagram of the acquisition device of suction type liquid sample involved in embodiments of the present invention.
Fig. 2 is to show the stereochemical structure of the acquisition device of suction type liquid sample involved in embodiments of the present invention
Figure.
Fig. 3 is to show the decomposition diagram of acquisition device shown in Fig. 2.
Fig. 4 is to show the schematic diagram of the diversion tube of acquisition device shown in Fig. 2.
Fig. 5 is to show the three-dimensional structure diagram of the diversion tube of acquisition device shown in Fig. 2.
Fig. 6 is to show the diagrammatic cross-section of the diversion tube of the hatching line A-A' along Fig. 5.
Fig. 7 is to show the three-dimensional structure diagram of the penetrating member of acquisition device involved in embodiments of the present invention.
Fig. 8 is to show the schematic diagram of the access of acquisition device involved in embodiments of the present invention.
Fig. 9 is to show the usage state diagram of the penetrating member of acquisition device involved in embodiments of the present invention.
Figure 10 is to show the three-dimensional structure diagram of the upper shield of acquisition device involved in embodiments of the present invention.
Specific embodiment
Hereinafter, explaining the preferred embodiment of the present invention in detail with reference to attached drawing.In the following description, for identical
Component assign identical symbol, the repetitive description thereof will be omitted.Scheme in addition, attached drawing is only schematical, the mutual ruler of component
Very little shape of ratio or component etc. can be with actual difference.
It should be noted that term " includes " and " having " and their any deformation in the present invention, such as wrapped
Include or the process, method, system, product or equipment of possessed a series of steps or units are not necessarily limited to be clearly listed that
A little step or units, but may include or with being not clearly listed or for these process, methods, product or equipment
Intrinsic other step or units.
Fig. 1 is to show the schematic diagram of the acquisition device of suction type liquid sample involved in embodiments of the present invention.
Fig. 2 is to show the three-dimensional structure diagram of the acquisition device of liquid sample involved in embodiments of the present invention.Fig. 3 is to show
The decomposition diagram of acquisition device shown in Fig. 2.
As shown in Figure 1, the acquisition device (below sometimes referred to as " acquisition device ") 1 of liquid sample involved in present embodiment
Including liquid storage pipe 10, diversion tube 20 and penetrating member 30.Wherein, diversion tube 20 has control liquid storage pipe 10 and penetrating member
The valves 23 (being described later on) of 30 connections, thus the operators such as doctor, nurse or other professionals can be conveniently by
Penetrating member 30 to the liquid sample in organizer (such as vitreum of eyes etc.) by negative pressure come automatic collection, and can
The collected liquid sample for being stored in liquid storage pipe is directly easily subjected to subsequent detection.
In the present embodiment, liquid storage pipe 10 can have seal cavity 11, and the air pressure of the seal cavity 11 is negative pressure.This
In, negative pressure is set according to different usages, that is to say, that the seal cavity 11 of liquid storage pipe 10 can be according to being wanted
At with different negative pressure, negative pressure at this time is limited to the gas of seal cavity 11 for liquid preparation of specimen in the different tissues of acquisition
Pressure is less than the intracorporal air pressure of tissue.For example, corresponding negative pressure is for intraocular liquid sample such as vitreous humor etc.
Refer to the air pressure for being less than intraocular pressure.
In some instances, seal cavity 11 can be formed as the subnormal ambient that air pressure is less than regulation air pressure, thus, it is possible to
Realize the automatic collection to liquid sample.In addition, in order to preferably carry out automatic collection, the usual phase of seal cavity 11 using negative pressure
For organizing intracorporal pressure.In some instances, the air pressure of seal cavity 11 can for example be set according to different usages
It is set to 5000Pa, 1000Pa, 500Pa, 100Pa etc..
In addition, the capacity of the seal cavity 11 of liquid storage pipe 10 it is not also specifically limited, can for 1mL to 20mL, 20mL extremely
50mL or 1mL to 100mL.Such as ophthalmology liquid sample, the volume (capacity) of seal cavity 11 can be 0.05mL
To 0.1mL, 0.1mL to 0.20mL or 0.20mL to 0.50mL.
In some instances, different models can be set into acquisition device 1 involved in present embodiment, correspondingly,
Capacity and vacuum magnitude in liquid storage pipe 10 can be different.Thereby, it is possible to improve the applicability of acquisition device 1.
In some instances, liquid storage pipe 10 can be in hollow cylinder.In addition, in other examples, liquid storage pipe
10 can be in hollow cuboid, hollow multiedge cylinder etc..Thus, it is possible to adapt to the liquid collection of specimens of different purposes.
In some instances, the bottom of liquid storage pipe 10 can be flat, and thus, it is possible to be conducive to the placement of liquid storage pipe 10.
In addition, in some instances, the bottom of liquid storage pipe 10 can also be indent, in this case, it is equally beneficial for liquid storage pipe
10 placement.
In some instances, liquid storage pipe 10 can be made of materials such as plastics, glass or metals.Face as a result, actual
In bed application, the operators such as doctor can be for the liquid storage pipe 10 of different liquid sample selection different materials.
In some instances, liquid storage pipe 10 can be transparent tube body.Thereby, it is possible to facilitate the operators such as doctor real-time
Observe the acquisition situation of the liquid sample of liquid storage pipe in ground.In some instances, liquid storage pipe 10 can be transparent glass tube or modeling
Expects pipe.In addition, in some instances, scale can be set in liquid storage pipe 10.For example, being provided in the outer surface of liquid storage pipe 10
Indicate the scale of liquid storage pipe capacity.In this case, the operators such as doctor can learn the acquisition of liquid sample in real time
Amount.
In some instances, the liquid sample collected of acquisition device 1 can be intraocular vitreous humor.In such case
Under, easily intraocular vitreous humor can be adopted automatically by negative pressure (being lower than intraocular pressure) characteristic in liquid storage pipe 10
Collection.
In some instances, in the outer surface of liquid storage pipe 10, anti-slipping mechanism can be set.Thereby, it is possible to facilitate doctor
Equal operators remove liquid storage pipe 10.In other examples, the outer surface of liquid storage pipe 10 can be set multiple protrusions and (not scheme
Show), the operators such as doctor can be facilitated to remove liquid storage pipe 10, liquid storage pipe 10 is avoided to slide from operator's hand.
In some instances, in addition liquid storage pipe 10 can also configure sealing cover (not shown).For example, when liquid storage pipe 10 acquires
After complete liquid sample, it can be unloaded from diversion tube 20, and cover liquid storage pipe 10 using sealing cover, it is subsequent thus, it is possible to guarantee
The liquid sample of liquid storage pipe 10 is also convenient for the preservation or inspection of the liquid sample of subsequent liquid storage pipe 10 not by outside contamination.
Fig. 4 is to show the schematic diagram of the diversion tube of acquisition device shown in Fig. 2.Fig. 5 is to show shown in Fig. 2 adopt
The three-dimensional structure diagram of the diversion tube of acquisition means.Fig. 6 is to show the section signal of the diversion tube of the line A-A' along Fig. 5
Figure.
In the acquisition device 1 involved in present embodiment, diversion tube 20 connect and is connected to liquid storage pipe 10, that is,
Access is formed between diversion tube 20 and liquid storage pipe 10.Specifically, diversion tube 20 can be with the seal chamber of liquid storage pipe 10
Body 11 is connected to, and since seal cavity 11 is in negative pressure state, liquid sample can be flowed into storage via diversion tube 20
The seal cavity 11 of liquid pipe 10.
In some instances, diversion tube 20 can form Rule with liquid storage pipe 10 and connect.For example, the one of diversion tube 20
End is that female Luer is connect with the formation of liquid storage pipe 10 Rule.In this case, diversion tube 20 can be removably installed in
Liquid storage pipe 10.
In addition, there is diversion tube 20 directed fluid inlet 21, diversion outlet 22 and setting to go out in directed fluid inlet 21 with water conservancy diversion
Valve 23 between mouth 22.
In the present embodiment, directed fluid inlet 21 can connect with penetrating member 30 and (be described later on), and diversion outlet 22 can
Opening and closing is controlled by valve 23 to be connected to liquid storage pipe 10, and between directed fluid inlet 21 and diversion outlet 22.In such case
Under, liquid storage pipe 10 can be controlled conveniently by control valve 23, and (especially penetrating member 30 is pierced into penetrating member 30
The intracorporal liquid sample of tissue) connection and closure.
In some instances, liquid storage pipe 10 is removably connect with diversion tube 20.As a result, to the liquid mark of liquid storage pipe 10
This acquisition finishes, and is separately separated liquid storage pipe 10 with can be convenient, directly carries out subsequent detecting step.For example, can will store up
Liquid pipe 10 is disassembled from diversion tube 20, and the liquid storage pipe 10 with liquid sample is directly carried out subsequent medicine inspection
It surveys, thus, it is possible to save detection time, improves the efficiency of clinical treatment.In some instances, valve 23 can be push type
Machinery valve.In this case, the operators such as doctor can be facilitated to operate the valve 23 of diversion tube, thus side
Just the acquisition of liquid sample is controlled.Specifically, the operators such as doctor can be by easily being controlled by pressure valve 23
Thus the automatic collection of liquid sample improves the clinical operation efficiency of doctor etc..
As shown in Figure 5 and Figure 6, in the present embodiment, valve 23 substantially may include press head 231 and press head 231
The body of rod 232 of connection, the inner cavity cooperated with the body of rod 232, the sealing ring 233 for being separately positioned on 232 different location of the body of rod and sealing
Circle 234 and the setting elastomeric element 235 in inner cavity 236.
In some instances, press head 231 can be round pie, thus, it is possible to facilitate the operators such as doctor to touch, side
Just it carries out the operation such as pressing.In addition, as shown in Fig. 2, show press head 231 in the situation of the side of valve 23, but the disclosure
Without being limited thereto, in some instances, the other side of valve 23 also can be set in press head 231.
In valve 23, elastomeric element 235 is changed by pressing press head 231, is existed at least be provided with the body of rod 232
First position and the second position in inner cavity 236.Such as when the body of rod 232 squeezes spring 235 and is in first position, water conservancy diversion enters
One end 21a of mouth 21 and one end 22a of diversion outlet 22 are between sealing ring 233 and sealing ring 234, in this case,
Directed fluid inlet 21 is connected with diversion outlet 22 via space 236, and liquid storage pipe 10 is via directed fluid inlet 21, diversion outlet 22 and thorn
Component 30 is worn to be connected to extraneous (organizer)；Such as when the body of rod 232 squeezes spring 235 and is in the second position, such as water conservancy diversion
One end 21a of entrance 21 is between sealing ring 233 and sealing ring 234, in this case, directed fluid inlet 21 and diversion outlet
22 are not connected to, and liquid storage pipe 10 is isolated from the outside.It in this way, can be by press head 231 come the unlatching of control valve 23
And closing, thus easily control have subnormal ambient liquid storage pipe 10 with the external world connection and be isolated.
In the present embodiment, the constituent material of valve 23 is not particularly limited, and in some instances, valve 23 can be
It is made of materials such as plastics, glass or metals.From the point of view of durable, valve 23 preferably uses metal material.
In addition, being also provided with the airtight stopper 24 for liquid storage pipe 10 to be embodied as to negative pressure in diversion tube 20.Tool
For body, in the case where diversion tube 20 (the specifically diversion outlet 22 of diversion tube 20) is connected to liquid storage pipe 10, pass through
Such as needle tubing penetrates the access of airtight stopper 24 to diversion outlet 22, and valve 23 is being kept to be in close state (directed fluid inlet at this time
21 are not connected to diversion outlet 22) in the case where carry out vacuumize process, thereby, it is possible to easily make the seal chamber of liquid storage pipe 10
Body 11 forms the environment of defined subnormal ambient such as less than intraocular pressure.
In addition, airtight stopper 24 can also maintain 10 negative pressure of liquid storage pipe.Specifically, due to extracting vacuum via airtight stopper 24
Afterwards, since airtight stopper 24 still is able to restore original state, the clogging access, therefore, airtight stopper 24 still are able to maintain liquid storage pipe
10 subnormal ambient.In some instances, airtight stopper 24 can be rubber stopper.
In addition, as described above, liquid storage pipe 10 is connect with diversion tube 20, and airtight stopper 24 is formed in leading for diversion tube 20
One end of outflux 22, in order to ensure airtight stopper 24 can be utilized to implement the Negative pressure entrance of liquid storage pipe 10, in liquid storage pipe
10 need at least to expose a part (referring to Fig. 8) of airtight stopper 24 with diversion tube 20 when connecting, use for example to extract vacuum
Needle tubing can penetrate airtight stopper 24.
In some instances, sealing ring 233 and sealing ring 234 can be made of medical grade rubber such as silica gel.At other
In example, sealing ring 233 and sealing ring 234 can also be by other medical material structures such as plastics, glass resin, synthetic compounds
At.Thereby, it is possible to guarantee the air-tightness of valve 23 while ensuring to meet requirement of the medical instrument for material.
In addition, in some instances, valve 23 or electrically operated valve.For example, the valve can detect air pressure simultaneously
Or hydraulic variation, after electrically operated valve unlatching detect air pressure or it is hydraulic lower than some value when, electrically operated valve is automatically closed, and makes
Directed fluid inlet 21 is not connected to diversion outlet 22.It in this case, being capable of more convenient operator's operation valve 23.
Fig. 7 is to show the three-dimensional structure diagram of the penetrating member of acquisition device involved in embodiments of the present invention.Fig. 8
It is to show the schematic diagram of the access of acquisition device involved in embodiments of the present invention.Fig. 9 is to show reality of the invention
Apply the usage state diagram of the penetrating member of acquisition device involved in mode.Figure 10 is shown involved by embodiments of the present invention
And acquisition device upper shield three-dimensional structure diagram.In Fig. 7, example is applied for convenience, shows acquisition device 1 for adopting
Collect the example of the vitreous humor in eyeball 2, however, the present invention is not limited thereto.
As shown in fig. 7, penetrating member 30 may include main body 31 and the puncture portion 32 connecting with main body 31.In addition, main body
31 can be connected to puncture portion 32, and thus liquid sample can flow through penetrating member 30 and reach diversion tube 20.
In some instances, in penetrating member 30, be formed between main body 31 and puncture portion 32 narrow access (referring to
Fig. 8), thus, it is possible to ensure liquid sample to cause because residing in main body 31 or puncture portion 32 flowing through penetrating member 30
The loss of liquid sample.The situation that this structure is extracted especially suitable for being directed to the few liquid sample such as aqueous humor of dosage.
In some instances, penetrating member 30 can form Rule with diversion tube 20 and connect.Such as diversion tube 20
Female Luer is formed close to one end of directed fluid inlet 21 and is formed Rule with penetrating member 30 and is connect.
In addition, in some instances, penetrating member 30 can be formed as one molding with diversion tube 20.In such case
Under, penetrating member 30 can be from the part that diversion tube 20 is drawn.
In some instances, in penetrating member 30, the restricted position-limit mechanism 33 for piercing through position can be set.It is specific and
The restricted position-limit mechanism 33 for piercing through position is arranged in speech between the main body 31 and puncture portion 32 of penetrating member 30.In this feelings
Under condition, when doctor etc., which will puncture through component 30, is pierced into organizer, puncture (piercing) position of penetrating member 30 is limited, it is possible thereby to
Convenient for the equal depth for controlling penetrating member 30 when acquiring aqueous humor and entering of doctor, penetrating member can be more accurately controlled
30 puncture position effectively avoids enter into too deep and patient is caused to receive secondary injury, improves the reliability of operation.
Here, it pierces through position and refers to that penetrating member 30 is pierced into the position of organizer, specifically, containing liquid by being pierced into
Then the organizer of sample passes through liquid storage pipe so that intracorporal liquid sample is organized to be connected to the seal cavity 11 of liquid storage pipe 10
10 negative pressure and to organizing intracorporal liquid sample to carry out automatic collection.
Penetrating member 30 shown in Fig. 9 is pierced into the example for obtaining vitreous humor sample in eyeball 2, and piercing through position should keep away
The positions such as iris are opened, cause to damage to avoid to above-mentioned tissue.In addition, it is necessary to explanation, penetrating member 30 shown in Fig. 9
The depth that operation direction and the puncture portion 31 of penetrating member 30 are pierced into eyeball is only example effect.
In some instances, position-limit mechanism 33 can be designed to fit in the surface of organizer, and thus, it is possible to play to pierce
The puncture portion 32 for wearing component 30 is self aligned to pierce through position.Thus, it is possible to facilitate the operators such as doctor to carry out puncture operation.
In some instances, penetrating member 30 can have protrusion 34.By protrusion 34, will puncture through with can be convenient
Component 30 disassembles or will puncture through component 30 from diversion tube 20 and is installed on diversion tube 20.Phase has can be set in protrusion 34
Pair two, more convenient can will puncture through component 30 in this way and disassemble or will puncture through component 30 from diversion tube 20 and be installed on
Diversion tube 20.
In some instances, penetrating member 30 can alongst can also be in by contracting shape.Thus, it is possible to facilitate doctor
The operators such as raw carry out the puncture to organizer, improve reliability and stability.
In addition, in some instances, penetrating member 30 can be needle tubing.In this case, since the front end of needle tubing is
It is tip-shape, therefore can be easy to pierce through organizer's such as eyeball etc..Thereby, it is possible to facilitate the operators such as doctor to pierce through organizer
Carry out the acquisition of liquid sample.
In some instances, the syringe needle outer diameter as the needle tubing of penetrating member 30, can be 0.31-4.57mm, in syringe needle
Diameter can be 0.15-3.81mm.Acquisition for the liquid sample such as ophthalmology, the syringe needle outer diameter of needle tubing be preferably 0.31mm extremely
0.64mm, internal diameter are preferably 0.15mm to 0.33mm, can either effectively acquire liquid sample as a result, can also realize wound most
Smallization accomplishes that safety is minimally invasive and makes a collection of specimens.
As described above, liquid storage pipe 1, diversion tube 2 and penetrating member 3 connect and are formed with narrow access (such as Fig. 8 institute
Show), thus liquid sample can be via penetrating member 3, diversion tube 2 and by automatic collection to liquid storage pipe 1.In such case
Under, liquid sample as much as possible can either be effectively collected, can also realize that wound minimizes, accomplishes the minimally invasive collection mark of safety
This.
In addition, in the present embodiment, the length in the puncture portion 32 of penetrating member 30 is not particularly limited, such as eye
For the liquid sample such as vitreous humor of section, the vitreum inside of eyes can be pierced into.
In the present embodiment, acquisition device 1 can also have upper shield 40 (referring to Fig. 3).In some instances, upper shield 40
It is removably installed in penetrating member 30.As shown in figure 3, by by liquid storage pipe 10, diversion tube 20, penetrating member 30 and upper shield
40 fit together, and so as to ensure that acquisition device 1 is in protected state, penetrating member 40 are avoided to accidentally injure the operation such as doctor
Personnel.In addition, upper shield 40 can prevent penetrating member 30 from being polluted by dust etc. with blocks dust.
In some instances, upper shield 40 can be the airtight cover for being covered in penetrating member 30.Thus, it is possible to further ensure that
The negative pressure state of liquid storage pipe 10.
In addition, in some instances, upper shield 40 can also cover penetrating member 30 and valve 23 simultaneously.In such case
Under, valve 23 can also obtain the protection of upper shield 40, and valve 23 is avoided to be misused.Here, the tail end of upper shield 40 can be according to valve
The structure of door 23 makees the adjustment of adaptability, so as to matchingly cover valve 23.
In some instances, upper shield 40 can be made of materials such as plastics, glass, metals.In some instances, upper shield 40
It can be in various shapes such as cylindrical body, cuboid, multiedge cylinder or anomalistic objects.
In some instances, it is also provided with skid resistance strip in the outer wall of upper shield 40 (referring to Figure 10).In some examples
In, skid resistance strip 41 can be set a plurality of, such as the peripheral direction of upper shield 40 be provided with four, eight or 12
Deng.In some instances, skid resistance strip 41 can be arranged along the length direction of upper shield 40, be formed as strip.
In addition, being also provided with protrusion in the outer wall of upper shield 40 in other examples.In other examples, set
The outer wall of lid 40 is also provided with Anti-slip cover.Thereby, it is possible to prevent from skidding in use.
Although being illustrated in conjunction with the accompanying drawings and embodiments to the present invention above, it will be appreciated that above description
The invention is not limited in any way.Those skilled in the art without departing from the true spirit and scope of the present invention may be used
To deform and change to the present invention as needed, these deformations and variation are within the scope of the present invention.
Claims (10)
1. a kind of acquisition device of suction type liquid sample, which is characterized in that
Include:
Liquid storage pipe, with seal cavity, the air pressure of the seal cavity is negative pressure；
Diversion tube is connected to the seal cavity of the liquid storage pipe, and there is directed fluid inlet, diversion outlet and setting to exist
Valve between the directed fluid inlet and the diversion outlet, the valve control the directed fluid inlet and the diversion outlet
Connection and closing；And
Penetrating member is used to pierce through organizer, and is connected to the directed fluid inlet of the diversion tube.
2. acquisition device as described in claim 1, which is characterized in that
The liquid storage pipe is removably connect with the diversion tube.
3. acquisition device as described in claim 1, which is characterized in that
The valve is the machinery valve of push type.
4. acquisition device as described in claim 1, which is characterized in that
The liquid sample is intraocular vitreous humor.
5. acquisition device as claimed in claim 4, which is characterized in that
In the penetrating member, the position-limit mechanism of restricted penetration depth is set.
6. acquisition device as described in claim 1, which is characterized in that
The outer surface of liquid storage pipe is provided with skid resistance strip.
7. acquisition device as described in claim 1, which is characterized in that
The liquid storage pipe is transparent tube body.
8. acquisition device as claimed in claim 7, which is characterized in that
In the liquid storage pipe, it is provided with scale.
9. acquisition device as described in claim 1, which is characterized in that further include removably being covered in the penetrating member
Upper shield.
10. acquisition device as described in claim 1, which is characterized in that the penetrating member is needle tubing.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111045008.6A CN113951936B (en) | 2018-04-11 | 2018-10-27 | Liquid specimen collection device with valve |
| CN202111046171.4A CN113693639B (en) | 2018-04-11 | 2018-10-27 | Collecting device for intraocular liquid specimen |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810322544.8A CN108433747A (en) | 2018-04-11 | 2018-04-11 | The harvester of suction type liquid sample |
| CN2018103225448 | 2018-04-11 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111045008.6A Division CN113951936B (en) | 2018-04-11 | 2018-10-27 | Liquid specimen collection device with valve |
| CN202111046171.4A Division CN113693639B (en) | 2018-04-11 | 2018-10-27 | Collecting device for intraocular liquid specimen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109363725A true CN109363725A (en) | 2019-02-22 |
| CN109363725B CN109363725B (en) | 2021-09-28 |
Family
ID=63199668
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810322544.8A Pending CN108433747A (en) | 2018-04-11 | 2018-04-11 | The harvester of suction type liquid sample |
| CN202111046171.4A Active CN113693639B (en) | 2018-04-11 | 2018-10-27 | Collecting device for intraocular liquid specimen |
| CN201811262140.0A Active CN109363725B (en) | 2018-04-11 | 2018-10-27 | Negative pressure type liquid specimen collecting device |
| CN202111045008.6A Active CN113951936B (en) | 2018-04-11 | 2018-10-27 | Liquid specimen collection device with valve |
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| CN202111046171.4A Active CN113693639B (en) | 2018-04-11 | 2018-10-27 | Collecting device for intraocular liquid specimen |
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| CN113995449A (en) * | 2021-12-01 | 2022-02-01 | 王乐乐 | Biopsy sampler for medical oncology department based on negative pressure principle |
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- 2018-10-27 CN CN202111046171.4A patent/CN113693639B/en active Active
- 2018-10-27 CN CN201811262140.0A patent/CN109363725B/en active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| CN113693639A (en) | 2021-11-26 |
| CN109363725B (en) | 2021-09-28 |
| CN113951936B (en) | 2024-02-27 |
| CN108433747A (en) | 2018-08-24 |
| CN113693639B (en) | 2024-02-27 |
| CN113951936A (en) | 2022-01-21 |
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