CN109349645A - Probiotic composition, health food and its preparation method and application - Google Patents
Probiotic composition, health food and its preparation method and application Download PDFInfo
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- CN109349645A CN109349645A CN201811279650.9A CN201811279650A CN109349645A CN 109349645 A CN109349645 A CN 109349645A CN 201811279650 A CN201811279650 A CN 201811279650A CN 109349645 A CN109349645 A CN 109349645A
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- probiotic composition
- bifidobacterium longum
- cfu
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- 239000006041 probiotic Substances 0.000 title claims abstract description 97
- 235000018291 probiotics Nutrition 0.000 title claims abstract description 97
- 239000000203 mixture Substances 0.000 title claims abstract description 93
- 230000000529 probiotic effect Effects 0.000 title claims abstract description 92
- 238000002360 preparation method Methods 0.000 title claims abstract description 33
- 235000013402 health food Nutrition 0.000 title claims abstract description 18
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 claims abstract description 52
- 241001608472 Bifidobacterium longum Species 0.000 claims abstract description 44
- 229940009291 bifidobacterium longum Drugs 0.000 claims abstract description 44
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- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
- A23V2400/533—Longum
Abstract
The present invention relates to a kind of probiotic compositions, health food and its preparation method and application.A kind of probiotic composition, according to parts by weight, it include: 0.3 part~0.9 part of bifidobacterium longum, 1 part~4 parts of γ-aminobutyric acid, 12 parts~18 parts of α-lactalbumin, 0.5 part~2 parts of red pomegranate extract and 60 parts~65 parts of collagen peptide, wherein, the viable count that the bifidobacterium longum contains is 6 × 1010CFU/g~1 × 1011CFU/g.Pass through bifidobacterium longum, γ-aminobutyric acid, α-lactalbumin, the synergistic effect of red pomegranate extract and collagen Gly-His-Lys, and control the number of viable in bifidobacterium longum, and make above-mentioned probiotics that can not only improve sleep quality, but also skin condition can be improved.
Description
Technical field
The present invention relates to food technology fields, more particularly to a kind of probiotic composition, health food and its preparation side
Method and application.
Background technique
Modern allegro life and gradually violent various competitive relations, keep people's stress increasing, spirit
Long-term nervous and a series of irregular rhythm of life, the insomnia caused annoyings always most people, and chronic insomnia
Also result in skin deterioration.
The pharmaceutical requirements of traditional treatment insomnia increase, and the drug for treating insomnia is also invented and produced with various states.
However not only effect cannot be affirmed the drug of traditional treatment insomnia mostly, but also hypnotic is by liver mostly in vivo
It is dirty, renal metabolism, take the burden that will increase liver kidney for a long time, some can also cause liver enlargement, hepatalgia, jaundice, float
The liver and kidney dysfunctions such as swollen, albuminuria, blood urine and nausea, abdominal distension, loss of appetite, constipation and stomach reaction；Some hypnotics are also
It will lead to lassitude, hypophrenia, the accumulation of poisoning symptom such as blood pressure decline, or even cause respiratory and circulatory function obstacle situation.
Summary of the invention
Based on this, it is necessary to provide a kind of probiotic composition for improving sleep quality and skin condition.
In addition, additionally providing a kind of preparation method and application of probiotic composition, health food and preparation method thereof.
A kind of probiotic composition, according to parts by weight, comprising:
Wherein, the viable count that the bifidobacterium longum contains is 6 × 1010CFU/g~1 × 1011CFU/g。
Above-mentioned bifidobacterium longum can not only supplement beneficial bacteria of intestinal tract, but also can be improved intestinal immunity, and improvement is slept
Dormancy quality, γ-aminobutyric acid have effects that increasing relieving mood, α-lactalbumin have effects that sleeping, adjust epiphysin,
Red pomegranate extract and collagen Gly-His-Lys have whitening, moisturizing, anti-oxidant and other effects, improve skin state.Pass through long bifid
Bacillus, γ-aminobutyric acid, α-lactalbumin, the synergistic effect of red pomegranate extract and collagen Gly-His-Lys, and control long double
Number of viable in discrimination bacillus, and make above-mentioned probiotics that can not only improve sleep quality, but also skin shape can be improved
State.
It in one of the embodiments, further include 2 parts~8 parts of oligofructose.
It in one of the embodiments, further include 0.1 part~0.4 part of Rhizoma amorphophalli extract.
It in one of the embodiments, further include 0.01 part~0.04 part of elastin laminin powder.
It in one of the embodiments, further include 10 parts~15 parts of Fruit powder.
A kind of probiotic composition, according to parts by weight, comprising:
Wherein, the viable count that the bifidobacterium longum contains is 6 × 1010CFU/g~1 × 1011CFU/g。
A kind of preparation method of probiotic composition, according to parts by weight, comprising steps of
0.3 part~0.9 part of bifidobacterium longum, 1 part~4 parts of γ-aminobutyric acid, 12 parts~18 parts of α-is milky white
Albumen, 0.5 part~2 parts of red pomegranate extract and the mixing of 60 parts~65 parts of collagen peptide, obtain probiotic composition,
Wherein, the viable count that the bifidobacterium longum contains is 6 × 1010CFU/g~1 × 1011 CFU/g。
Probiotic composition made from the preparation method of above-mentioned probiotic composition or above-mentioned probiotic composition exists
Prepare the application in health food.
A kind of health food, the preparation method system including above-mentioned probiotic composition or above-mentioned probiotic composition
The probiotic composition and food additives obtained.
A kind of preparation method of health food, comprising steps of
By probiotic composition made from the preparation method of above-mentioned probiotic composition or above-mentioned probiotic composition
It is mixed with food additives, obtains health food.
Specific embodiment
The invention can be realized in many different forms, however it is not limited to embodiment described herein.On the contrary,
Purpose of providing these embodiments is makes the disclosure of the present invention more thorough and comprehensive.
Unless otherwise defined, all technical and scientific terms used herein and belong to technical field of the invention
The normally understood meaning of technical staff it is identical.Term as used herein in the specification of the present invention is intended merely to retouch
State the purpose of specifically embodiment, it is not intended that in the limitation present invention.
The probiotic composition of one embodiment, according to parts by weight, comprising:
Wherein, the viable count that bifidobacterium longum contains is 6 × 1010CFU/g~1 × 1011CFU/g.Bifidobacterium longum is made
For probiotics, intestinal immunity is improved while can be used for supplementing beneficial bacteria of intestinal tract, improves sleep quality.Further, long double
The mass fraction of discrimination bacillus is 0.625 part.Specifically, bifidobacterium longum is bifidobacterium longum BB536.
Wherein, γ-aminobutyric acid belongs to strong neural inhibitory aminoacid, has calmness, hypnosis, anticonvulsion and blood pressure lowering
Physiological action can be used for relieving mood.Further, the mass fraction of γ-aminobutyric acid is 2.5 parts.
Wherein, α-lactalbumin helps to relieve stress, and improves work performance, and having improves sleep, adjusts epiphysin
Effect.Further, the mass fraction of α-lactalbumin is 15 parts.
Wherein, red pomegranate extract has anti-oxidant, antiphlogistic antibacterial and other effects, and effective component is anthocyanidin, pomegranate is more
Phenol, ellagic acid, these ingredients are all extremely strong antioxidant, can effective delaying skin aging, moisturizing, crease-resistant.Further
Ground, the mass fraction of red pomegranate extract are 1.25 parts.Specifically, red pomegranate extract is Pomella red pomegranate extract.
Wherein, collagen peptide has the effect of removing interior free yl, anti-oxidant slowing down skin aging.Further,
The mass fraction of collagen peptide is 62.5 parts.Specifically, collagen peptide is powder.
It should be noted that above-mentioned probiotic composition further includes the oligofructose that mass fraction is 2 parts~8 parts.It is oligomeric
Fructose can improve functions of intestines and stomach, and generate synergistic effect with bifidobacterium longum, and further increase intestinal immunity, improve
Sleep quality.Further, the mass fraction of oligofructose is 5.35 parts.
It should be noted that above-mentioned probiotic composition further includes that the konjaku that mass fraction is 0.1 part~0.4 part extracts
Object.Rhizoma amorphophalli extract can aid in the protection of skin, moist, moisturizing etc..Further, the mass fraction of Rhizoma amorphophalli extract
It is 0.25 part.Specifically, Rhizoma amorphophalli extract is match network beauty.
It should be noted that above-mentioned probiotic composition further includes the elastic egg that mass fraction is 0.01 part~0.04 part
White powder.Elastin laminin powder can improve the elasticity and flexibility of skin, and having prevents aging and the regenerated effect of promotion.Into one
Step ground, the mass fraction of elastin laminin powder are 0.025 part.
It should be noted that above-mentioned probiotic composition further includes the Fruit powder that mass fraction is 10 parts~15 parts.Fruit
Powder can improve the mouthfeel of probiotic composition.Further, the mass fraction of Fruit powder is 12.5 parts.Specifically, Fruit powder
For strawberry fruit powder.
Above-mentioned probiotic composition at least has the advantages that
1) above-mentioned bifidobacterium longum can not only supplement beneficial bacteria of intestinal tract, but also can be improved intestinal immunity, improve
Sleep quality, γ-aminobutyric acid have effects that increase relieving mood, the function that α-lactalbumin has sleeping, adjusts epiphysin
Effect, red pomegranate extract and collagen Gly-His-Lys have whitening, moisturizing, anti-oxidant and other effects, improve skin state.Pass through length
Bifidobacterium, γ-aminobutyric acid, α-lactalbumin, the synergistic effect of red pomegranate extract and collagen Gly-His-Lys, and control
Number of viable in bifidobacterium longum, and make above-mentioned probiotics that can not only improve sleep quality, but also skin can be improved
State.
2) above-mentioned probiotic composition further includes the oligofructose that mass fraction is 2 parts~8 parts.Oligofructose can change
Kind functions of intestines and stomach, and synergistic effect is generated with bifidobacterium longum, and intestinal immunity is further increased, improve sleep quality.
The preparation method of the probiotic composition of one embodiment is one of preparation of above-mentioned probiotic composition
Method, according to parts by weight, comprising the following steps:
0.3 part~0.9 part of bifidobacterium longum, 1 part~4 parts of γ-aminobutyric acid, 12 parts~18 parts of α-is milky white
Albumen, 0.5 part~2 parts of red pomegranate extract and the mixing of 60 parts~65 parts of collagen peptide, obtain probiotic composition,
Wherein, the viable count that bifidobacterium longum contains is 6 × 1010CFU/g~1 × 1011CFU/g。
Further, the mass fraction of bifidobacterium longum is 0.625 part.Specifically, bifidobacterium longum is bifidobacterium longum
BB536。
Further, the mass fraction of γ-aminobutyric acid is 2.5 parts.
Further, the mass fraction of α-lactalbumin is 15 parts.
Further, the mass fraction of red pomegranate extract is 1.25 parts.Specifically, red pomegranate extract is Verdure
The Pomella red pomegranate extract of Science company production, wherein contain Punica granatum L. polyphenol >=50%, containing punicalagins >=10%~
30%.
Further, the mass fraction of collagen peptide is 62.5 parts.Specifically, collagen peptide is powder.
Further, by 0.3 part~0.9 part of bifidobacterium longum, 1 part~4 parts of γ-aminobutyric acid, 12 parts~18 parts
α-lactalbumin, 0.5 part~2 parts of red pomegranate extract and 60 parts~65 parts collagen peptide mixing the step of before,
It further include by 0.3 part~0.9 part of bifidobacterium longum, 1 part~4 parts of γ-aminobutyric acid, 12 parts~18 parts of the milky white egg of α-
The step of white, 0.5 part~2 parts of red pomegranate extract and the drying of 60 parts~65 parts of collagen peptide, sieving.
Specifically, dry step are as follows: under conditions of 50 DEG C~70 DEG C, by 0.3 part~0.9 part of bifidobacterium longum,
1 part~4 parts of γ-aminobutyric acid, 12 parts~18 parts of α-lactalbumin, 0.5 part~2 parts of red pomegranate extract and 60 parts
~65 parts of collagen peptide drying to moisture content is lower than 3%.
Specifically, in the step of sieving, the mesh number of sieve is 50 mesh~70 mesh.
It should be noted that by 0.3 part~0.9 part of bifidobacterium longum, 1 part~4 parts of γ-aminobutyric acid, 12 parts~
The step of 18 parts of α-lactalbumin, 0.5 part~2 parts of red pomegranate extract and mixing of 60 parts~65 parts of collagen peptide
In, it is also added into the oligofructose that mass fraction is 2 parts~8 parts.Further, the mass fraction of oligofructose is 5.35 parts.
It should be noted that by 0.3 part~0.9 part of bifidobacterium longum, 1 part~4 parts of γ-aminobutyric acid, 12 parts~
The step of 18 parts of α-lactalbumin, 0.5 part~2 parts of red pomegranate extract and mixing of 60 parts~65 parts of collagen peptide
In, it is also added into the Rhizoma amorphophalli extract that mass fraction is 0.1 part~0.4 part.Further, the mass fraction of Rhizoma amorphophalli extract
It is 0.25 part.Specifically, Rhizoma amorphophalli extract is Unitika company of Japan match network beauty produced.
It should be noted that by 0.3 part~0.9 part of bifidobacterium longum, 1 part~4 parts of γ-aminobutyric acid, 12 parts~
The step of 18 parts of α-lactalbumin, 0.5 part~2 parts of red pomegranate extract and mixing of 60 parts~65 parts of collagen peptide
In, it is also added into the elastin laminin powder that mass fraction is 0.01 part~0.04 part.Further, the mass parts of elastin laminin powder
Number is 0.025 part.
It should be noted that by 0.3 part~0.9 part of bifidobacterium longum, 1 part~4 parts of γ-aminobutyric acid, 12 parts~
The step of 18 parts of α-lactalbumin, 0.5 part~2 parts of red pomegranate extract and mixing of 60 parts~65 parts of collagen peptide
In, it is also added into the Fruit powder that mass fraction is 10 parts~15 parts.Further, the mass fraction of Fruit powder is 12.5 parts.Tool
Body, Fruit powder is strawberry fruit powder.
The preparation method of above-mentioned probiotic composition is simple to operation, is suitable for industrialized production.
Probiotic composition made from the preparation method of above-mentioned probiotic composition or above-mentioned probiotic composition exists
Prepare the application in health food.
The health food of one embodiment, the system including above-mentioned probiotic composition or above-mentioned probiotic composition
Probiotic composition made from Preparation Method and food additives.The health food can be lozenge, chewable tablets or solid beverage,
Have the function of improving sleep quality and skin condition, and in good taste, nutritional ingredient is easy to absorb.
The preparation method of the health food of one embodiment, comprising steps of by above-mentioned probiotic composition or above-mentioned
Probiotic composition made from the preparation method of probiotic composition is mixed with food additives, obtains health food.The health care
The preparation method of food is simple to operation, is suitable for industrialized production.
The following are specific embodiment parts:
Embodiment 1
The preparation step of the probiotic composition of the present embodiment is as follows:
1) 0.625 part of bifidobacterium longum BB536,2.5 parts of γ-aminobutyric acid, 15 parts according to parts by weight, are weighed
α-lactalbumin, 1.25 parts of Pomella red pomegranate extract, 62.5 parts of collagen Gly-His-Lys, 5.35 parts of oligomeric fruit
The raw materials such as sugar, 0.25 part of Rhizoma amorphophalli extract, 0.025 part of elastin laminin powder and 12.5 parts of strawberry fruit powder, wherein long double
The viable count that discrimination bacillus BB536 contains is 6 × 1010CFU/g~1 × 1011CFU/g；
2) above-mentioned raw materials are dried under conditions of 60 DEG C to moisture content and is lower than 3%, be then sieved, be uniformly mixed, obtain
To probiotic composition, wherein the mesh number of sieve is 60 mesh.
Embodiment 2
The preparation step of the probiotic composition of the present embodiment is as follows:
1) 0.3 part of bifidobacterium longum BB536,1 part of γ-aminobutyric acid, 12 parts of α-according to parts by weight, are weighed
Lactoalbumin, 0.5 part of Pomella red pomegranate extract, 60 parts of collagen Gly-His-Lys, 2 parts of oligofructose, 0.1 part
The raw materials such as Rhizoma amorphophalli extract, 0.01 part of elastin laminin powder and 10 parts of strawberry fruit powder, wherein bifidobacterium longum BB536 contains
Viable count be 6 × 1010CFU/g~1 × 1011CFU/g；
2) above-mentioned raw materials are dried under conditions of 50 DEG C to moisture content and is lower than 3%, be then sieved, be uniformly mixed, obtain
To probiotic composition, wherein the mesh number of sieve is 50 mesh.
Embodiment 3
The preparation step of the probiotic composition of the present embodiment is as follows:
1) 0.9 part of bifidobacterium longum BB536,4 parts of γ-aminobutyric acid, 18 parts of α-cream according to parts by weight, are weighed
Albumin, 2 parts of Pomella red pomegranate extract, 65 parts of collagen Gly-His-Lys, 8 parts of oligofructose, 0.4 part of konjaku
The raw materials such as extract, 0.04 part of elastin laminin powder and 15 parts of strawberry fruit powder, wherein the work that bifidobacterium longum BB536 contains
Bacterium number is 6 × 1010CFU/g~1 × 1011CFU/g；
2) above-mentioned raw materials are dried under conditions of 70 DEG C to moisture content and is lower than 3%, be then sieved, be uniformly mixed, obtain
To probiotic composition, wherein the mesh number of sieve is 70 mesh.
Comparative example 1
The preparation step of the probiotic composition of this comparative example is as follows:
1) 0.125 part of bifidobacterium longum BB536,2.5 parts of γ-aminobutyric acid, 15 parts according to parts by weight, are weighed
α-lactalbumin, 1.25 parts of Pomella red pomegranate extract, 63 parts of collagen peptide, 5.35 parts of oligofructose,
The raw materials such as 0.25 part of Rhizoma amorphophalli extract, 0.025 part of elastin laminin powder and 12.5 parts of strawberry fruit powder, wherein long bifid bar
The viable count that bacterium BB536 contains is 6 × 1010CFU/g~1 × 1011CFU/g；
2) above-mentioned raw materials are dried under conditions of 60 DEG C to moisture content and is lower than 3%, be then sieved, be uniformly mixed, obtain
To probiotic composition, wherein the mesh number of sieve is 60 mesh.
Comparative example 2
The preparation step of the probiotic composition of this comparative example is as follows:
1) 0.625 part of bifidobacterium longum BB536,1 part of γ-aminobutyric acid, 12 parts according to parts by weight, are weighed
α-lactalbumin, 1.25 parts of Pomella red pomegranate extract, 62.825 parts of collagen peptide, 10.175 parts of oligomeric fruit
The raw materials such as sugar, 0.25 part of Rhizoma amorphophalli extract, 0.025 part of elastin laminin powder and 12.5 parts of strawberry fruit powder, wherein long double
The viable count that discrimination bacillus BB536 contains is 6 × 1010CFU/g~1 × 1011CFU/g；
2) above-mentioned raw materials are dried under conditions of 60 DEG C to moisture content and is lower than 3%, be then sieved, be uniformly mixed, obtain
To probiotic composition, wherein the mesh number of sieve is 60 mesh.
Comparative example 3
The preparation step of the probiotic composition of this comparative example is as follows:
1) 2.5 parts of γ-aminobutyric acid, 15 parts of α-lactalbumin, 1.25 parts according to parts by weight, are weighed
Pomella red pomegranate extract, 62.5 parts of collagen Gly-His-Lys, 5.35 parts of oligofructose, 0.25 part of konjaku extract
The raw materials such as object, 0.025 part of elastin laminin powder and 12.5 parts of strawberry fruit powder；
2) above-mentioned raw materials are dried under conditions of 60 DEG C to moisture content and is lower than 3%, be then sieved, be uniformly mixed, obtain
To probiotic composition, wherein the mesh number of sieve is 60 mesh.
Comparative example 4
The preparation step of the probiotic composition of the present embodiment is as follows:
1) 0.625 part of bifidobacterium longum BB536,15 parts of α-lactalbumin, 1.25 parts according to parts by weight, are weighed
Pomella red pomegranate extract, 62.5 parts of collagen Gly-His-Lys, 5.35 parts of oligofructose, 0.25 part konjaku extract
The raw materials such as object, 0.025 part of elastin laminin powder and 12.5 parts of strawberry fruit powder, wherein the work that bifidobacterium longum BB536 contains
Bacterium number is 6 × 1010CFU/g~1 × 1011CFU/g；
2) above-mentioned raw materials are dried under conditions of 60 DEG C to moisture content and is lower than 3%, be then sieved, be uniformly mixed, obtain
To probiotic composition, wherein the mesh number of sieve is 60 mesh.
Comparative example 5
The preparation step of the probiotic composition of the present embodiment is as follows:
1) 0.625 part of bifidobacterium longum BB536,2.5 parts of γ-aminobutyric acid, 1.25 parts according to parts by weight, are weighed
Pomella red pomegranate extract, 62.5 parts of collagen Gly-His-Lys, 5.35 parts of oligofructose, 0.25 part konjaku extract
The raw materials such as object, 0.025 part of elastin laminin powder and 12.5 parts of strawberry fruit powder, wherein the work that bifidobacterium longum BB536 contains
Bacterium number is 6 × 1010CFU/g~1 × 1011CFU/g；
2) above-mentioned raw materials are dried under conditions of 60 DEG C to moisture content and is lower than 3%, be then sieved, be uniformly mixed, obtain
To probiotic composition, wherein the mesh number of sieve is 60 mesh.
Test:
1) influence of the probiotic composition to mouse weight
80 mouse are selected to be tested, half male and half female, weight 18g~24g is divided into 8 groups, and 4 groups of female is 4 groups male.4
In group, 1 group of blank control group feeds distilled water；3 groups are experimental group, respectively according to 1.0g/kg, 3.0g/kg, 5.0g/kg
The solid beverage of the probiotic composition preparation of embodiment 1 is given in dosage stomach-filling, according to the amount of mouse 20mL/kg BW, 12
Gastric infusion in hour, fasting 15 hours, can't help water, ends a hunger strike within 3 hours after administration before mouse is administered.Successive administration 30 days, during which
Observe the changes of weight of mouse.Experimental result is as shown in table 1:
Table 1
As it can be seen from table 1 body weight increase does not differ significantly between experiment mice each group dosage, products obtained therefrom pair
Male and female mouse weight illustrates that probiotic composition made from embodiment 1 does not influence tested material weight without influence.
In addition, observation it has also been found that, the mouse of probiotic composition made from stomach-filling embodiment 1 compared with the control group, hair
More smooth with skin, activity is more flexible.
2) probiotic composition improves the test of sleep quality
Male and female mouse each 240, it is randomly divided into 6 experimental groups, respectively experimental group 1, control group 1, control group 2, control
Group 3, control group 4 and control group 5, then each experimental group gives the probiotic composition of the embodiment 1 of isometric dosage respectively
Solid beverage made from solid beverage obtained and the probiotic composition of comparative example 1~5, wherein experimental group 1, which is given, to be implemented
Solid beverage made from the probiotic composition of example 1, control group 1 give the drink of solid made from the probiotic composition of comparative example 1
Material, control group 2 give solid beverage made from the probiotic composition of comparative example 2, and control group 3 gives the probiotics of comparative example 3
Solid beverage made from composition, control group 4 give solid beverage made from the probiotic composition of comparative example 4, control group 5
Give solid beverage made from the probiotic composition of comparative example 5.
Wherein, each experimental group is divided into 4 groups, and 10 mouse of each group give equal bodies in a manner of stomach-filling respectively
Accumulate the solid beverage of the water of dosage, the solid beverage of 0.1g/kg, the solid beverage of 0.5g/kg, 1.5g/kg, wherein 0.1g/
Kg, 0.5g/kg and 1.5g/kg respectively indicate the content of probiotic composition in the solid beverage given according to the weight of mouse.
Daily stomach-filling 1 time, continuous gavage 15 days.After last stomach-filling 15min, penta bar of 50mg/kg BW ratio is injected intraperitoneally to groups of animals
Appropriate sodium, injection volume are 0.3mL/20g BW, and to right transmitting hour as sleep judgment criteria, whether observation given the test agent extends
Yellow Jackets sleeping time, mouse hypnagogic latency time the results are shown in Table 2.
Table 2
From table 2 it can be seen that the hypnagogic latency time difference for giving experimental group 1 has statistics compared with 0 dosage group
Meaning (P < 0.05), i.e. dosage of the solid beverage made from the probiotic composition of embodiment 1 in 0.5g/kg and 1.5g/kg
Group can extend the sleeping time of yellow Jackets induction, illustrate that probiotic composition made from embodiment 1 can improve sleep matter
Amount.
In addition, observation also found, the mouse of solid beverage made from the probiotic composition of stomach-filling embodiment 1 and stomach-filling
The mouse of solid beverage made from the probiotic composition of comparative example 1~5 is compared, and hair and skin are more smooth, and activity is more
Flexibly.Illustrate that probiotic composition made from embodiment 1 can improve skin condition and hair luster.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to guarantor of the invention
Protect range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.
Claims (10)
1. a kind of probiotic composition, which is characterized in that according to parts by weight, comprising:
Wherein, the viable count that the bifidobacterium longum contains is 6 × 1010CFU/g~1 × 1011CFU/g。
2. probiotic composition according to claim 1, which is characterized in that further include 2 parts~8 parts of oligofructose.
3. probiotic composition according to claim 1, which is characterized in that further include 0.1 part~0.4 part of konjaku extraction
Object.
4. probiotic composition according to claim 1, which is characterized in that further include 0.01 part~0.04 part of elastic egg
White powder.
5. probiotic composition according to claim 1, which is characterized in that further include 10 parts~15 parts of Fruit powder.
6. a kind of probiotic composition, which is characterized in that according to parts by weight, comprising:
Wherein, the viable count that the bifidobacterium longum contains is 6 × 1010CFU/g~1 × 1011CFU/g。
7. a kind of preparation method of probiotic composition, which is characterized in that according to parts by weight, comprising steps of
By 0.3 part~0.9 part of bifidobacterium longum, 1 part~4 parts of γ-aminobutyric acid, 12 parts~18 parts of α-lactalbumin,
0.5 part~2 parts of red pomegranate extract and the mixing of 60 parts~65 parts of collagen peptide, obtain probiotic composition, wherein institute
Stating the viable count that bifidobacterium longum contains is 6 × 1010CFU/g~1 × 1011CFU/g。
8. the preparation method system of probiotic composition described in claim 1~6 or probiotic composition as claimed in claim 7
The probiotic composition obtained is preparing the application in health food.
9. a kind of health food, which is characterized in that including the described in any item probiotic compositions of claim 1~6 or right
It is required that probiotic composition made from the preparation method of probiotic composition described in 7 and food additives.
10. a kind of preparation method of health food, which is characterized in that comprising steps of
By the preparation of the described in any item probiotic compositions of claim 1~6 or probiotic composition as claimed in claim 7
Probiotic composition made from method is mixed with food additives, obtains health food.
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Application publication date: 20190219 |
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