CN109304062A - A kind of improved pipe-line system for setting air filter and its sterilizing methods - Google Patents
A kind of improved pipe-line system for setting air filter and its sterilizing methods Download PDFInfo
- Publication number
- CN109304062A CN109304062A CN201710615754.1A CN201710615754A CN109304062A CN 109304062 A CN109304062 A CN 109304062A CN 201710615754 A CN201710615754 A CN 201710615754A CN 109304062 A CN109304062 A CN 109304062A
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- CN
- China
- Prior art keywords
- valve
- pipe
- steam
- air
- filter
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
- B01D46/0084—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours provided with safety means
- B01D46/0087—Bypass or safety valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/04—Heat
- A61L2/06—Hot gas
- A61L2/07—Steam
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
- B01D46/0027—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours with additional separating or treating functions
- B01D46/0028—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours with additional separating or treating functions provided with antibacterial or antifungal means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2279/00—Filters adapted for separating dispersed particles from gases or vapours specially modified for specific uses
- B01D2279/65—Filters adapted for separating dispersed particles from gases or vapours specially modified for specific uses for the sterilisation of air
Abstract
The present invention relates to air filter sterilization technology fields, specifically a kind of improved pipe-line system for setting air filter and its sterilizing methods, it is characterized by also including the first bypass pipes for being equipped with steam bypass valve, one end is connected on the compressed air inlet pipe between air inlet valve and air filter for removing bacteria, and the other end is connected on the pure steam inlet pipe of the inlet side of steam inlet valve；One end of control valve is also connected on the filter housing of air filter for removing bacteria bottom；It is also connected with a drain pipe on filter outlet pipe, is successively arranged exhaust valve, thermometer, steam trap along emission direction on the drain pipe；The other end of one end connection control valve of second bypass pipe, the other end of the second bypass pipe are connected on the drain pipe between exhaust valve and thermometer.Compared with the existing technology, pipe-line system transformation is simple by the present invention, without disassembly when air filter for removing bacteria sterilizes, i.e., realizes online sterilizing using the pure steam in the system of primary tube road, prevents secondary pollution.
Description
Technical field
The present invention relates to air filter sterilization technology field, specifically a kind of improved pipe for setting air filter
Road system and its sterilizing methods.
Background technique
In pharmaceutical production, some containers, equipment, pipeline etc. can use technique compressed air purge, pressure maintaining, and in order to protect
The cleanliness and aseptic of compressed air are demonstrate,proved, the compressed air inlet port of these components would generally install hydrophobic air sterilization additional
Filter 3, and the long-time service of the filter core of air filter for removing bacteria 3 can accumulate microorganism, decline degerming ability, therefore periodically need
Sterilization treatment is carried out to the filter core in gas sterilizing filter 3.
The traditional sterilization treatment mode of filter core in air filter for removing bacteria 3, personnel are cumbersome, disassembly assembly when under
Play pipe mouth causes secondary pollution, the filtering function of air filter for removing bacteria 3 can be lost in the short time, the later period is again without corresponding processing
Measure；
For the container for the compressed air medium that needs to be sterile filtered, equipment, pipeline generally all can with use pure steam, one
As be designed as shared compressed air/pure steam outlet pipe Vavle switching air or pure steam exported by air outlet valve and pure steam
Medium；Referring to Fig. 1, traditional air filter for removing bacteria 3 its be configured with: its import installation 1 air inlet valve, generally adopt
Use ball valve；1 air outlet valve is installed in its outlet, generally uses diaphragm valve；The subsequent piping connection three of air outlet valve
One in logical is logical, it is another lead to connect pure steam inlet pipe, and 1 steam inlet valve, steam inlet are installed on pure steam inlet pipe 1-2
Valve also uses diaphragm valve, and the third of threeway, which is led to, connects shared compressed air/pure steam outlet pipe, air filter for removing bacteria and its matches
The operating procedure that part generally dismantles, uses is as follows:
1. closing the air inlet valve of air filter for removing bacteria；
2. opening exhaust valve exhaust pressure relief；
3. after the completion of pressure release, dismantling the clip of air filter for removing bacteria import and export, keep air filter for removing bacteria empty from compression
It is removed on gas inlet pipe, and air filter for removing bacteria is moved in sterilizing cabinet and is sterilized offline, at this time under air filter for removing bacteria
It swims to this section of filter outlet pipe of air outlet valve and has lost germ-free condition；
4. after the completion of air filter for removing bacteria sterilizing, being packed into sealing in hermetic bag, moving to compressed air inlet pipe and filter
Installation position between outlet；
5. remove hermetic bag rapidly, take out air filter for removing bacteria be installed on compressed air inlet pipe and filter outlet pipe it
Between.At this time since disassembly acts, the air filter for removing bacteria after making sterilizing is exposed to a period of time in non-sterile air, at this time
Destroyed the integral asepsis state of air filter for removing bacteria, the contaminated degree of pipe-line system are influenced the operating time by personnel；
6. after installation is in place, pipe-line system opens the air inlet valve pressure maintaining above air filter for removing bacteria, empty after qualified
The down-stream system of gas sterilizing filter can select using medium to be pressure by the switching of air outlet valve and pure steam outlet valve
Contracting air or pure steam.
Summary of the invention
The purpose of the present invention is overcome the deficiencies in the prior art, by increasing some pipelines and valve in original pipe-line system
Door etc. realizes the online sterilizing to air filter for removing bacteria using the pure steam in the system of primary tube road, without disassembly, letter
Change personnel operation, effectively avoids secondary pollution, ensure that the aseptic of entire pipe-line system.
To achieve the above object, a kind of improved pipe-line system for setting air filter is designed, including
Air filter for removing bacteria；
Compressed air inlet pipe, connects the input end at the top of air filter for removing bacteria, and the compressed air inlet pipe is equipped with
Air inlet valve；
Filter outlet pipe, one end connect the outlet at bottom end of air filter for removing bacteria, and other end connection air goes out
One end of mouth valve；
Pure steam inlet pipe, outlet end connect one end of steam inlet valve；
Compressed air/pure steam outlet pipe, the discharge air or pure steam being used for；
Tee tube, first leads to the other end for connecing air outlet valve, and second leads to the other end for connecing steam inlet valve；Third
Lead to and connects compressed air/pure steam outlet pipe input end；
It is characterized by:
It further include the first bypass pipe, first bypass pipe is equipped with steam bypass valve, and one end of the first bypass pipe connects
It connects on the compressed air inlet pipe between air inlet valve and air filter for removing bacteria, the other end of the first bypass pipe is connected to steaming
On the pure steam inlet pipe of the inlet side of vapor inlet valve；
One end of control valve is also connected on the filter housing of the air filter for removing bacteria bottom；
Be also connected with a drain pipe on filter outlet pipe, on the drain pipe along emission direction be successively arranged exhaust valve,
Thermometer, steam trap；
The other end of one end connection control valve of second bypass pipe, the other end of the second bypass pipe are connected to exhaust valve and temperature
It spends on the drain pipe between table.
Ball valve is respectively adopted in the air inlet valve, control valve, steam bypass valve.
Diaphragm valve is respectively adopted in the air outlet valve, steam inlet valve, exhaust valve.
The sterilizing methods of the pipe-line system, it is characterised in that:
The original state of a1, the system pipeline are as follows: air inlet valve is open state, steam inlet valve is to close shape
State, air outlet valve, exhaust valve, control valve, steam bypass valve are respectively at closed state；
A2, air inlet valve is closed；
A3, exhaust valve is opened, the compressed air in air filter for removing bacteria and filter outlet pipe is discharged through drain pipe；
After the completion of a4, exhaust pressure relief, the control valve of air filter for removing bacteria bottom is opened, and opens steam bypass valve to sky
Gas sterilizing filter, control valve, the second bypass pipe, filter outlet pipe, exhaust valve, thermometer interface carry out steam go out online
Bacterium:
B1, when the temperature display on thermometer is more than 111 DEG C, close control valve；
B2, after the state that the temperature display on thermometer is more than 121 DEG C is for 10 seconds, be again turned on control valve；
When b3, the temperature when show on thermometer are more than 121 DEG C of maintenance 30min, then online sterilizing is completed；
A5, steam off by-passing valve open air inlet valve and carry out reset purging, and the temperature to show on thermometer drops to
At 55 DEG C, it is again switched off control valve；The temperature shown on purging to thermometer is after room temperature, remaining valve of system pipeline is successively multiple
Position.
Compared with the existing technology, pipe-line system transformation is simple, without disassembly when air filter for removing bacteria sterilizes, i.e., by the present invention
Online sterilizing is realized using the pure steam in original pipe-line system, is prevented secondary pollution, is guaranteed the sterile of entire pipe-line system
Property.
Detailed description of the invention
Fig. 1 is the connection schematic diagram of original pipeline for setting air filter.
Fig. 2 is connection schematic diagram of the invention.
Referring to FIG. 1 to FIG. 2, wherein 1-1 is compressed air inlet pipe；1-2 is pure steam inlet pipe；1-3 is filter outlet
Pipe；1-4 is compressed air/pure steam outlet pipe；1-5 is the first bypass pipe；1-6 is the second bypass pipe；1-7 is drain pipe；
2-1 is air inlet valve；2-2 is air outlet valve；2-3 is steam inlet valve；2-4 is exhaust valve；2-5 is control
Valve；2-6 is steam bypass valve；
3 be air filter for removing bacteria；4 be thermometer；5 be steam trap.
Specific embodiment
The present invention is described further below with reference to embodiment.
The present invention connects the components such as additional pipeline and valve, thermometer, steam trap in original pipe-line system
Transformation is completed, transformation is very easy, and pass through switching related valve and sterilizing online is realized by the pure steam in former pipe-line system,
Pure steam refers to that purified water is the steam of raw water preparation in the present invention.
Embodiment 1
Referring to fig. 2, a kind of improved pipe-line system for setting air filter of the present invention, including
Air filter for removing bacteria 3；
Compressed air inlet pipe 1-1, the input end at 3 top of connection air filter for removing bacteria, the compressed air inlet pipe 1-1
It is equipped with air inlet valve 2-1；
Filter outlet pipe 1-3, one end connect the outlet at bottom end of air filter for removing bacteria 3, and other end connection is empty
One end of gas outlet valve 2-2；
Pure steam inlet pipe 1-2, outlet end connect one end of steam inlet valve 2-3；
Compressed air/pure steam outlet pipe 1-4, the discharge air or pure steam being used for；
Tee tube, first leads to the other end for meeting air outlet valve 2-2, and second leads to and meet the another of steam inlet valve 2-3
End；Third, which is led to, connects compressed air/pure steam outlet pipe 1-4 input end；
It is characterized by:
It further include that the first bypass pipe 1-5, the first bypass pipe 1-5 is equipped with steam bypass valve 2-6, the first bypass pipe
One end of 1-5 is connected on the compressed air inlet pipe 1-1 between air inlet valve 2-1 and air filter for removing bacteria 3, the first bypass
The other end of pipe 1-5 is connected on the pure steam inlet pipe 1-2 of the inlet side of steam inlet valve 2-3；
One end of control valve 2-5 is also connected on the filter housing of 3 bottom of air filter for removing bacteria；
It is also connected on filter outlet pipe 1-3 on drain pipe a 1-7, the drain pipe 1-7 and is successively set along emission direction
There are exhaust valve 2-4, thermometer 4, steam trap 5；
The other end of one end connection control valve 2-5 of second bypass pipe 1-6, the other end of the second bypass pipe 1-6 are connected to
On drain pipe 1-7 between exhaust valve 2-4 and thermometer 4.
Further, ball valve is respectively adopted in the air inlet valve 2-1, control valve 2-5, steam bypass valve 2-6.
Further, diaphragm valve is respectively adopted in the air outlet valve 2-2, steam inlet valve 2-3, exhaust valve 2-4.
The sterilizing methods of heretofore described pipe-line system, it is characterised in that:
The original state of a1, the system pipeline are as follows: air inlet valve 2-1 is open state, steam inlet valve 2-3 is pass
Closed state, air outlet valve 2-2, exhaust valve 2-4, control valve 2-5, steam bypass valve 2-6 are respectively at closed state；
A2, air inlet valve 2-1 is closed；
A3, exhaust valve 2-4 is opened, makes the compressed air in air filter for removing bacteria 3 and filter outlet pipe 1-3 through hydrophobic
Pipe 1-7 discharge；
After the completion of a4, exhaust pressure relief, the control valve 2-5 of 3 bottom of air filter for removing bacteria is opened, and opens steam bypass valve
2-6 is to air filter for removing bacteria 3, control valve 2-5, the second bypass pipe 1-6, filter outlet pipe 1-3, exhaust valve 2-4, thermometer
4 interface carries out steam and sterilizes online:
B1, when the temperature display on thermometer 4 is more than 111 DEG C, close control valve 2-5；
B2, after the state that the temperature display on thermometer 4 is more than 121 DEG C is for 10 seconds, be again turned on control valve 2-5；
When b3, the temperature when show on thermometer 4 are more than 121 DEG C of maintenance 30min, then online sterilizing is completed；
A5, steam off by-passing valve 2-6 open air inlet valve 2-1 and carry out reset purging, to what is shown on thermometer 4
When temperature drops to 55 DEG C, it is again switched off control valve 2-5；Purge after being room temperature to the temperature shown on thermometer 4, system pipeline its
Remaining valve successively resets.
Traditional pipe-line system for setting air filter needs personnel to dismantle air filter for removing bacteria 3 and moves in sterilizing cabinet
Sterilizing；And the present invention realizes online sterilizing by the pure steam in pipe-line system without disassembly, simplifies personnel's operation；
Traditional pipe-line system for setting air filter, air filter for removing bacteria 3 is exposed to non-sterile air when operation
In, the downstream pipe of air filter for removing bacteria 3 loses gnotobasis；And the present invention in operation air filter for removing bacteria 3 be
Line sterilizing, not only ensure that the degerming of air filter for removing bacteria 3, but also remove simultaneously to the downstream pipe of air filter for removing bacteria 3
Bacterium ensure that whole aseptic.
Claims (4)
1. a kind of improved pipe-line system for setting air filter, including
Air filter for removing bacteria (3)；
Compressed air inlet pipe (1-1) connects the input end at the top of air filter for removing bacteria (3), the compressed air inlet pipe (1-
1) it is equipped with air inlet valve (2-1)；
Filter outlet pipe (1-3), one end connect the outlet at bottom end of air filter for removing bacteria (3), and other end connection is empty
One end of gas outlet valve (2-2)；
Pure steam inlet pipe (1-2), outlet end connect the one end of steam inlet valve (2-3)；
Compressed air/pure steam outlet pipe (1-4), the discharge air or pure steam being used for；
Tee tube, first leads to the other end for meeting air outlet valve (2-2), and second leads to and meet the another of steam inlet valve (2-3)
End；Third, which is led to, connects compressed air/pure steam outlet pipe (1-4) input end；
It is characterized by:
It further include the first bypass pipe (1-5), first bypass pipe (1-5) is equipped with steam bypass valve (2-6), the first bypass
One end of pipe (1-5) is connected to the compressed air inlet pipe (1-1) between air inlet valve (2-1) and air filter for removing bacteria (3)
On, the other end of the first bypass pipe (1-5) is connected on the pure steam inlet pipe (1-2) of the inlet side of steam inlet valve (2-3)；
One end of control valve (2-5) is also connected on the filter housing of described air filter for removing bacteria (3) bottom；
It is also connected on filter outlet pipe (1-3) drain pipe (1-7), on the drain pipe (1-7) successively along emission direction
Equipped with exhaust valve (2-4), thermometer (4), steam trap (5)；
The other end of one end connection control valve (2-5) of second bypass pipe (1-6), the other end connection of the second bypass pipe (1-6)
On drain pipe (1-7) between exhaust valve (2-4) and thermometer (4).
2. pipe-line system as described in claim 1, it is characterised in that: the air inlet valve (2-1), control valve (2-5),
Ball valve is respectively adopted in steam bypass valve (2-6).
3. pipe-line system as described in claim 1, it is characterised in that: the air outlet valve (2-2), steam inlet valve
Diaphragm valve is respectively adopted in (2-3), exhaust valve (2-4).
4. the sterilizing methods of pipe-line system as described in any one of claims 1 to 3, it is characterised in that:
The original state of a1, the system pipeline are as follows: air inlet valve is open state, steam inlet valve is in off state, empty
Gas outlet valve, exhaust valve, control valve, steam bypass valve are respectively at closed state；
A2, air inlet valve (2-1) is closed；
A3, exhaust valve (2-4) is opened, makes the compressed air in air filter for removing bacteria (3) and filter outlet pipe (1-3) through dredging
Water pipe (1-7) discharge；
After the completion of a4, exhaust pressure relief, the control valve of air filter for removing bacteria bottom is opened, and opens steam bypass valve and air is removed
Bacterium filter, control valve, the second bypass pipe, filter outlet pipe, exhaust valve, thermometer interface carry out steam sterilize online:
B1, when the temperature display on thermometer (4) is more than 111 DEG C, close control valve (2-5)；
B2, after the state that the temperature display on thermometer (4) is more than 121 DEG C is for 10 seconds, be again turned on control valve (2-5)；
When b3, the temperature when show on thermometer (4) are more than 121 DEG C of maintenance 30min, then online sterilizing is completed；
A5, steam off by-passing valve (2-6) open air inlet valve (2-1) and carry out reset purging, to show on thermometer (4)
Temperature when dropping to 55 DEG C, be again switched off control valve (2-5)；The temperature shown on purging to thermometer (4) is system after room temperature
Remaining valve of pipeline successively resets.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710615754.1A CN109304062A (en) | 2017-07-26 | 2017-07-26 | A kind of improved pipe-line system for setting air filter and its sterilizing methods |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710615754.1A CN109304062A (en) | 2017-07-26 | 2017-07-26 | A kind of improved pipe-line system for setting air filter and its sterilizing methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109304062A true CN109304062A (en) | 2019-02-05 |
Family
ID=65201793
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710615754.1A Pending CN109304062A (en) | 2017-07-26 | 2017-07-26 | A kind of improved pipe-line system for setting air filter and its sterilizing methods |
Country Status (1)
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| CN (1) | CN109304062A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114669559A (en) * | 2022-03-17 | 2022-06-28 | 罗益（无锡）生物制药有限公司 | On-line cleaning and sterilizing equipment for clean compressed air system |
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