CN206577491U - Gas-filtering device - Google Patents
Gas-filtering device Download PDFInfo
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- CN206577491U CN206577491U CN201720211535.2U CN201720211535U CN206577491U CN 206577491 U CN206577491 U CN 206577491U CN 201720211535 U CN201720211535 U CN 201720211535U CN 206577491 U CN206577491 U CN 206577491U
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- Prior art keywords
- gas
- valve
- pneumatic filter
- bioreactor
- filtering device
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Abstract
The utility model discloses a kind of gas-filtering device, for bioreactor, gas-filtering device includes a pneumatic filter, a gas inlet pipeline, a steam pipework, a control valve group, a discharge pipe line;Steam pipework is connected to the air inlet of pneumatic filter, and steam pipework is provided with a steam inlet valve, discharge pipe line is connected to the bottom of pneumatic filter and is connected with the inside of pneumatic filter, and discharge pipe line is provided with a draining valve, and gas inlet pipeline is provided with a gas inlet valve;Control valve group is all connected to hydrophobic pipeline, the gas outlet of pneumatic filter and bioreactor, and control valve group is changeable cut-offs the first path and alternate path.The utility model can realize the online filter core changed and blocked in pneumatic filter, and can carry out local online sterilizing, so as in time, thoroughly solve the blockage problem of pneumatic filter, it is ensured that the normal operation of bioreactor, it is to avoid unnecessary stopping production.Meanwhile, easy to use, stable operation.
Description
Technical field
The utility model is related to a kind of gas-filtering device.
Background technology
Bioreactor is the biological function having using enzyme or organism, and the device system of biochemical reaction is carried out in vitro
System, is a kind of biological function analog machine, such as fermentation tank, immobilised enzymes or immobilized cell reactor.
In bioreactor system, air cleaner is indispensable part, is provided for bioprocesses
Required aseptic gas, it is ensured that biological respinse is normally carried out.Traditional bioreactor is filter and the direct phase of reactor
Even, easily there is clogging in air cleaner running, especially when cultivation cycle length, gas flow are big, more sternly
Weight.Once blocking, that is, cause supply not enough, cause organism metabolism slow, activity reduction is even dead, is forced to stop production.
Utility model content
The technical problems to be solved in the utility model is in order to overcome existing pneumatic filter easily to block, to cause supply not
Foot, in addition stop production etc. defect there is provided a kind of gas-filtering device.
The utility model is to solve above-mentioned technical problem by following technical proposals:
A kind of gas-filtering device, for bioreactor, the gas-filtering device includes a pneumatic filter, one
Gas inlet pipeline, the air inlet of the pneumatic filter is connected to the gas inlet pipeline, and the pneumatic filter goes out
Gas port is used to be connected to the bioreactor, and its feature is, the gas-filtering device also includes a steam pipework, one
Control valve group, a discharge pipe line;
The steam pipework is connected to the air inlet of the pneumatic filter, and the steam pipework enters provided with a steam
Air valve, the discharge pipe line is connected to the bottom of the pneumatic filter and is connected with the inside of the pneumatic filter, institute
Discharge pipe line is stated provided with a draining valve, the gas inlet pipeline is provided with a gas inlet valve;
The control valve group is all connected to hydrophobic pipeline, the gas outlet of the pneumatic filter and the bioreactor,
And the control valve group is changeable cut-offs the first path and alternate path, first path is sequentially connected the gas filtration
Device, the control valve group, the bioreactor, the alternate path are sequentially connected the pneumatic filter, the control valve
Group, the hydrophobic pipeline.
It is preferred that the control valve group includes one first valve, one second valve, the two ends difference of first valve
The pneumatic filter and the bioreactor are connected to, the two ends of second valve are connected to the gas filtration
Device and the hydrophobic pipeline.
In this programme, using said structure form, pipeline cut-off it is simple to operate, be easy to control.
It is preferred that first valve and second valve are pneumatic diaphragm valve.
In this programme, using said structure form, automatically controlling for sterilizing can be realized by jettron.
It is preferred that the draining valve is removably attachable to the discharge pipe line by clip, the steam inlet valve is led to
Cross clip and be removably attachable to the steam pipework, the gas inlet valve is removably attachable to the gas by clip
Air inlet pipeline, the control valve group is removably attachable to the hydrophobic pipeline, the pneumatic filter by clip and gone out
Gas port, the bioreactor.
In this programme, using said structure form, realization is detachably connected mode, easy to replace and maintain.
It is preferred that the top of the pneumatic filter be provided with a gas blowdown piping, the gas blowdown piping with it is described
The inside of pneumatic filter is connected, and the gas blowdown piping is provided with an atmospheric valve.
In this programme, using said structure form, it can realize the gas discharge inside pneumatic filter, prevent gas
Body residual causes sterilizing not thorough.
It is preferred that the atmospheric valve is removably attachable to the gas blowdown piping by clip, the discharge pipe line,
The steam pipework, the gas inlet pipeline are removably attachable to the pneumatic filter by clip.
In this programme, using said structure form, realization is detachably connected mode, easy to replace and maintain.
It is preferred that the draining valve, the steam inlet valve and the gas inlet valve are pneumatic diaphragm valve.
In this programme, using said structure form, it can realize that sterilizing is automatically controlled by jettron.
On the basis of common sense in the field is met, above-mentioned each optimum condition can be combined, produce the utility model it is each compared with
Good example.
Positive effect of the present utility model is:
Gas-filtering device of the present utility model, can be achieved the online filter core changed and blocked in pneumatic filter, and can enter
The local online sterilizing of row, so as in time, thoroughly solve the blockage problem of pneumatic filter, it is ensured that the normal fortune of bioreactor
OK, it is to avoid unnecessary stopping production.Meanwhile, easy to use, stable operation.
Brief description of the drawings
Fig. 1 is the structural representation of the gas-filtering device of the utility model preferred embodiment.
Description of reference numerals:
Bioreactor 1
Pneumatic filter 2, filter core 21, gas blowdown piping 22, atmospheric valve 23
Gas inlet pipeline 3, gas inlet valve 31
Steam pipework 4, steam inlet valve 41
Control valve group 5, the first valve 51, the second valve 52
Discharge pipe line 6, draining valve 61
Hydrophobic pipeline 7
Embodiment
Below by embodiment mode and become apparent from intactly illustrating the utility model with reference to accompanying drawing, but not therefore
The utility model is limited among described scope of embodiments.
As shown in figure 1, gas-filtering device of the present utility model is used for bioreactor 1, gas-filtering device includes
One pneumatic filter 2, a gas inlet pipeline 3, a steam pipework 4, a control valve group 5, a discharge pipe line 6, pneumatic filter 2
Air inlet be connected to gas inlet pipeline 3, the gas outlet of pneumatic filter 2 is used to be connected to bioreactor 1, is biological anti-
Device 1 is answered to provide required aseptic gas, it is ensured that biological respinse is normally carried out in bioreactor 1.
Steam pipework 4 is connected to the air inlet of pneumatic filter 2, and steam pipework 4 is provided with a steam inlet valve 41, steams
Vapour intake valve 41 is used to control cut-offfing for steam pipework 4;Discharge pipe line 6 be connected to the bottom of pneumatic filter 2 and with gas mistake
The inside of filter 2 is connected, and discharge pipe line 6 is provided with a draining valve 61, and draining valve 61 is used to control cut-offfing for discharge pipe line 6;
Gas inlet pipeline 3 is provided with a gas inlet valve 31, and gas inlet valve 31 is used to control cut-offfing for gas inlet pipeline 3.
The two ends of control valve group 5 are connected to gas outlet and the bioreactor 1 of pneumatic filter 2, and control valve group 5
For controlling cut-offfing between pneumatic filter 2 and bioreactor 1.Filter core in changing or safeguarding pneumatic filter 2
When 21, control valve group 5 is closed so that pneumatic filter 2 is separated with bioreactor 1, so as to gas filtration
Filter core 21 in device 2 is safeguarded or changed, and effectively solves filter core 21 and occurs blockage problem.Preferably, control valve group 5 close to
Bioreactor 1.
Meanwhile, control valve group 5 is also attached to hydrophobic pipeline 7, and changeable the first path and second that cut-offs of control valve group 5 leads to
Road, the first path is sequentially connected pneumatic filter 2, control valve group 5, bioreactor 1, and alternate path is sequentially connected gas filtration
Device 2, control valve group 5, hydrophobic pipeline 7.When changing filter core 21, the first path is disconnected, online replacing gas filtration can be achieved
The filter core 21 blocked in device 2.
When carrying out sterilization process to gas-filtering device, the first path and gas inlet in first closing control valve group 5
Valve 31, opens the alternate path in draining valve 61 and control valve group 5, slow to open steam inlet valve 41, treats discharge pipe line 6 and dredges
When in water lines 7 without discharge condensed water, the alternate path in draining valve 61 and control valve group 5 is turned down, discharge pipe line 6 is treated and dredges
When the temperature of water lines 7 all reaches 121 DEG C and the above, when starting the sterilometer to gas-filtering device, steam off after 30min
Intake valve 41, opens gas inlet valve 31, after pneumatic filter 2 is cooled to room temperature, closes in draining valve 61 and control valve group 5
Alternate path, sterilizing terminates.In whole sterilization process, the first path in control valve group 5 is constantly in closed mode, leads to
Local online sterilizing of the steam to gas-filtering device is crossed, so as in time, thoroughly solve the blockage problem of pneumatic filter 2, is protected
Demonstrate,prove the normal operation of bioreactor 1.Meanwhile, easy to use, stable operation.In sterilization process, discharge pipe line 6 and drain pipe
The temperature of road 7 and sterilization time are simultaneously not limited to the above.
Control valve group 5 is connected to pneumatic filter 2, bioreactor 1 and hydrophobic pipeline 7 simultaneously so that control valve group 5 has
There is the valve group of three way type structure, in order to reach the effect for being easy to operational control, control valve group 5 can include one first valve
51st, one second valve 52, the two ends of the first valve 51 are connected to pneumatic filter 2 and bioreactor 1, the second valve 52
Two ends be connected to pneumatic filter 2 and hydrophobic pipeline 7.First path, the second valve 52 are controlled by the first valve 51
Alternate path is controlled, facilitates staff to use, is easy to control.
First valve 51 and the second valve 52 can be pneumatic diaphragm valve, are prevented effectively from control valve group 5 and occur leakage now
As.Meanwhile, compressed gas is realized is cut-off automatically, and automatically controlling for sterilizing can be realized by jettron.
Draining valve 61 can be removably attachable to discharge pipe line 6 by clip, and steam inlet valve 41 can pass through clip
Steam pipework 4 is removably attachable to, gas inlet valve 31 can be removably attachable to gas inlet pipeline 3 by clip,
Control valve group 5 can be removably attachable to hydrophobic pipeline 7, the gas outlet of pneumatic filter 2, bioreactor by clip
1.Connected between structure by removably, be easy to the replacing and maintenance of valve.
The top of pneumatic filter 2 can be provided with a gas blowdown piping 22, gas blowdown piping 22 and pneumatic filter 2
Inside be connected, and gas blowdown piping 22 be provided with an atmospheric valve 23, atmospheric valve 23 be used for control gas blowdown piping 22
Cut-off, can be realized when in sterilization process by inside pneumatic filter 2 gas discharge, prevent gas residue cause sterilizing
It is not thorough.
Atmospheric valve 23 can be removably attachable to gas blowdown piping 22 by clip, discharge pipe line 6, steam pipework 4,
Gas inlet pipeline 3 can be removably attachable to pneumatic filter 2 by clip.It is easy to the replacing to pneumatic filter 2
And maintenance.Preferably, draining valve 61, steam inlet valve 41 and gas intake valve 31 can be pneumatic diaphragm valve, by pneumatic
Switch can realize that sterilizing is automatically controlled.
Although the foregoing describing embodiment of the present utility model, it will be appreciated by those of skill in the art that
This is merely illustrative of, and protection domain of the present utility model is defined by the appended claims.Those skilled in the art
On the premise of without departing substantially from principle of the present utility model and essence, various changes or modifications can be made to these embodiments,
But these changes and modification each fall within protection domain of the present utility model.
Claims (7)
1. a kind of gas-filtering device, for bioreactor, the gas-filtering device includes a pneumatic filter, a gas
Body air inlet pipeline, the air inlet of the pneumatic filter is connected to the gas inlet pipeline, the outlet of the pneumatic filter
Mouth is used to be connected to the bioreactor, it is characterised in that the gas-filtering device also includes a steam pipework, a control
Valve group processed, a discharge pipe line;
The steam pipework is connected to the air inlet of the pneumatic filter, and the steam pipework is provided with a steam inlet
Valve, the discharge pipe line is connected to the bottom of the pneumatic filter and is connected with the inside of the pneumatic filter, described
Discharge pipe line is provided with a draining valve, and the gas inlet pipeline is provided with a gas inlet valve;
The control valve group is all connected to hydrophobic pipeline, the gas outlet of the pneumatic filter and the bioreactor, and institute
State that control valve group is changeable to cut-off the first path and alternate path, first path is sequentially connected the pneumatic filter, institute
Control valve group, the bioreactor are stated, the alternate path is sequentially connected the pneumatic filter, the control valve group, institute
State hydrophobic pipeline.
2. gas-filtering device as claimed in claim 1, it is characterised in that the control valve group include one first valve,
One second valve, the two ends of first valve are connected to the pneumatic filter and the bioreactor, described
The two ends of two valves are connected to the pneumatic filter and the hydrophobic pipeline.
3. gas-filtering device as claimed in claim 2, it is characterised in that first valve and second valve are
Pneumatic diaphragm valve.
4. gas-filtering device as claimed in claim 1, it is characterised in that the draining valve is detachably connected by clip
In the discharge pipe line, the steam inlet valve is removably attachable to the steam pipework, the gas inlet by clip
Valve is removably attachable to the gas inlet pipeline by clip, and the control valve group is removably attachable to by clip
The hydrophobic pipeline, the gas outlet of the pneumatic filter, the bioreactor.
5. gas-filtering device as claimed in claim 1, it is characterised in that the top of the pneumatic filter is provided with a gas
Blowdown piping, the gas blowdown piping is connected with the inside of the pneumatic filter, and is set on the gas blowdown piping
There is an atmospheric valve.
6. gas-filtering device as claimed in claim 5, it is characterised in that the atmospheric valve is detachably connected by clip
In the gas blowdown piping, the discharge pipe line, the steam pipework, the gas inlet pipeline are detachable by clip
Ground is connected to the pneumatic filter.
7. the gas-filtering device as any one of claim 1-6, it is characterised in that the draining valve, the steam
Intake valve and the gas inlet valve are pneumatic diaphragm valve.
Priority Applications (1)
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CN201720211535.2U CN206577491U (en) | 2017-03-06 | 2017-03-06 | Gas-filtering device |
Applications Claiming Priority (1)
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CN201720211535.2U CN206577491U (en) | 2017-03-06 | 2017-03-06 | Gas-filtering device |
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CN206577491U true CN206577491U (en) | 2017-10-24 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109529068A (en) * | 2018-11-26 | 2019-03-29 | 山西大禹生物工程股份有限公司 | The intelligent disinfecting technique of accurate filter |
-
2017
- 2017-03-06 CN CN201720211535.2U patent/CN206577491U/en active Active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109529068A (en) * | 2018-11-26 | 2019-03-29 | 山西大禹生物工程股份有限公司 | The intelligent disinfecting technique of accurate filter |
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