CN109288738A - A kind of eyeshield composition and its eye patch and preparation method - Google Patents
A kind of eyeshield composition and its eye patch and preparation method Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0208—Tissues; Wipes; Patches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
Abstract
The present invention relates to a kind of eye paste technical field of membrane, relate more specifically to a kind of eyeshield composition for cooperating microcurrent stimulating and its eye patch and preparation method, with cicada extract, Puerarin, beta carotene, silymarin, cannabis oil, beta glucan and dried tremella extract etc. are used as primary raw material, synergistic effect between raw material components makes in the eye sticker film composition containing small molecule active nutriment cicada fungus polysaccharide needed for eye, beta glucan, acidic polysaccharose, neutral heteropolysaccharide. and acid oligosaccharides, energy source abundant is provided for eye circumference cell repair, the effective component cannabidiol of the cannabis oil of specificity addition, taurine and Puerarin are to calm optic nerve, microcirculation is promoted to have effect unique, by eye patch combination micro-current equipment, the special efficacy imported with micro-current, effective component can be promoted by eye circumference cave Position absorbs and utilizes, and makes to prevent, correcting defects of vision is enhanced with the effect of restoring ocular cell.
Description
Technical field
The present invention relates to a kind of eye paste technical field of membrane, relate more specifically to a kind of eyeshield group for cooperating microcurrent stimulating
Close object and its eye patch and preparation method.
Background technique
Eyes are in the state that adjusting is loosened, before parallel rays focuses on retina after eye refraction system, referred to as
Myopia.Myopia is also referred to as short-sighted eye, because this eye, which can only be seen, cannot closely see far.This eye during the break, comes from unlimited distance
Directional light by eye dioptric system refractive power after, focus is assembled before retina, is then formed on the retina unclear
As distant vision is substantially reduced, but near vision is still normal.The internal cause of myopia has: inherent cause and developmental factors;Outside myopia
Cause: i.e. environmental factor is engaged in paperwork or the people of other near works, and myopia is relatively more, near-sighted in adolescent student
Eye also compares more, and since primary school five, six grades, illness rate obviously rises.This phenomenon illustrates the generation of myopia
It is very close with the relationship of near work with developing.Especially teen-age eyeball is in growth and development stage, adjusts energy
Power is very strong, and the extensibility of ball wall is also bigger, read etc. near works when adjusting sum aggregate cooperation use, make internal rectus muscle to eyeball
Apply certain pressure, intraocular pressure also accordingly increases, with being continuously increased for operation, adjust and the frequency gathered and time also by
Cumulative to add, often in high-pressure state, the excessive performance of adjustment effect can cause ciliary muscle convulsion for ciliary muscle and extraocular muscle
Contraction, so as to cause momentary hypopsia.But it is rested or using after ciliary muscle vesicant, eyesight may improve or completely extensive
It is multiple.Therefore, someone claims this to be nearly functional myopia or pseudo-myopia.
Existing some therapeutic schemes have, and 1, wear glasses;2, operative treatment: operation on cornea, crystalline lens and intraocular implants
Body operation, sclera rear portion Reinforcement;3, drug is controlled;4, other treatment: other are all not to harm eye and has controlling for certain theoretical foundation
Treatment method, such as fogging method, eyes close as method and close as eyesight improving instrument, look far into the distance method, ciliary muscle exercise method can try out.
For pre- myopia prevention and correction, there is the eyesight screening instrument detected for eyesight, eyesight screening instrument is detected and fitted
For children and adult: 1, automatic, non-invasi;2, quick and effective;3, it makes a response without patient;4, it is suitable for children;
5, objectivity;6, safe and accurate dioptric information.It is portable that detector design simultaneously makes screening be easier 1, simplicity;2, comfortable essence
Skilful design;3, strict guard box;4, screening range is wide.
With the development of internet technology, computer, mobile phone and various terminals show the universal and application of equipment, are people's
Life and amusement provide rich and varied service, however the blue light that the LED backlight of these device screens issues is to long-time service
Human eye cause serious injury.Blue light is a kind of visible light of shortwave high energy, the retina of its energy direct projection to eyes depths
On, heavier burden is brought to eyes, or even can damage to retina, generate lesion, blindness is also resulted in when serious.For
, there is anti-blue light eyeglass on the market in this, although wound of the anti-blue light eyeglass energy blocking harmful blue light to eyes to a certain extent
Evil, but on the other hand, just due to having worn anti-blue light eyeglass, many people do not pay attention to eye hygiene, continue to stare at for a long time
Screen, can equally aggravate the burden of eyes in this way, cause the decline of eyesight, so, wear anti-blue light glasses barrier injury
While source, eye nutrition is supplemented, enhance eyes itself resistance, it is reasonably combined between at the moment, alleviate eye strain.
In addition, some crowds are due to working principle, it has to computer, mobile phone and various terminal equipment be used for a long time, make eye
Eyeball is at daily to be regarded in close state, and eyes long sight function cannot use for a long time, and intraocular pressure is chronically at higher state, compressing
Crystal keeps axis oculi elongated, cause over time eye muscle it is stiff, decline, continue to decline to further result in eyesight, myopia
Degree is deepened.
For myopia, existing therapeutic scheme has: 1, wearing glasses;2, operative treatment: operation on cornea, crystalline lens and artificial
Operation on lens, sclera rear portion Reinforcement;3, drug is controlled;4, treat: other are all not to harm eye and has controlling for certain theoretical foundation
Treatment method, such as fogging method, eyes close as method and close as eyesight improving instrument, look far into the distance method, ciliary muscle exercise method can try out.
Eye patch is vast female group for eye microgroove of releiving, and is the common skin care item that eye part skin supplements the nutrients,
But these eye patch products not can solve myopia problem.Therefore, research and development are a can facilitate in free time for people
Supplement the nutrients in eye muscle of releiving, for eyes, by the research and experiment of science show the nutrition of reasonable eye consumption at
Divide and other assist functional components, and can cooperate microcurrent stimulating that eye acupuncture point is promoted to absorb its effective active composition,
By the metabolic capability of adjusting liver and renal function, protection liver, kidney simultaneously enhance caused by asthenopia functional component
The processing of metabolin, thus realize myopia prevention and treatment very it is necessary to.
Summary of the invention
For this reason, it may be necessary to provide a kind of eyeshield composition and its pad pasting, can conveniently make for eye strain person in free time
Releive eye muscle, for eyes supplement the nutrients, and be able to maintain that and enhance eyes itself resistance eyeshield composition and
Its pad pasting.
To achieve the above object, a kind of eyeshield composition is inventor provided, by weight percentage, including with the following group
Point:
Beta glucan is a kind of polysaccharide being widely present in microorganism, mushroom and plant, it is composition higher plant, ferment
One of female bacterium and the structural macromolecules of fungal cell wall can adjust cell growth, can promote the generation of internal IgM antibody, with
The immunocompetence for improving body fluid is added the raw material and is advantageous in that in the eyeshield composition that the technical program provides, adjustment and
Impaired periocular muscle group and optic nerve are repaired, the resistance of eye crystalline lens, optic nerve and ciliary muscle is improved.
Alginic acid to avoid cutaneous anaphylaxis and can enhance the stability of product, and seaweed as Adjunct humectants
Acid can form weak acid alkali neutralization with the chitosan oligosaccharide ingredient with antibiotic bioactive, preferably stablize and disperse eyeshield composition
Effective component, the best compatibility that the present invention analyzes in long-term research and development and experimentation, while can be steady well
Determine the activity of other compositions, two mixing can play good facilitation, can not only be retained but also can be played very in patch
Good anti-inflammatory antibacterial effect.It is commercially available generally based on sodium alginate product, the present invention utilizes the commercially available raw material seaweed being easy to get
Sour sodium passes through film dialysis technology, removes sodium ion ingredient, obtains alginic acid, then carries out preparation deep processing with other compositions and matches
5, it gives full play to moisturizing, surfactant and skin is promoted to absorb nutrition and other effects.
Chitosan oligosaccharide is called Chitosan poly oligosaccharide, chitosan oligomer, is a kind of polymerization that chitosan is degraded through special process
Degree oligosaccharide product, molecular weight≤3200Da between 2~20 are water solubility is preferable, function is big, bioactivity is high low points
Son amount product.It has the unexistent higher solubility of chitosan, is dissolved in water entirely, be easy to be absorbed and utilized etc. by organism it is many solely
Special function is intended to improve the following performance of the technical program product: moisturizing it acts as 14 times of chitosan using chitosan oligosaccharide
Property, activation body cell, prevent pachylosis and aging.
Dried tremella extract contains the glycogen such as trehalose, pentosan, mannitol, and nutritive value is very high, has righting strong
Strong effect is a kind of advanced nourishing tonic.Modern medical studies have confirmed that the pharmacology effective component of tremella is tremella polysaccharides: main
It is made of acidic polysaccharose, neutral heteropolysaccharide., acid oligosaccharides etc., tremella polysaccharides have apparent antioxidation, and have and increase
The immune effect with humoral immunity of strong man's body cell, therefore dried tremella extract has moisturizing and nourishing and enhancing eye to periocualr skin
The effect of portion's immunity.
The technical program is advantageous in that using taurine, has a good nutritive effect to retina, and can be with
It adjusts the osmotic pressure of crystal and prevents the protein in crystal from excessive oxidation occurs, in addition to this, taurine can also strong liver benefit
Gallbladder, enhancing eye resist the immune function of external damage.
Cannabis oil, effective component are cannabidiol (CBD), are one of the main chemical compositions in hemp, extract from female
Property hemp plant, unlike another chemical component tetrahydrocannabinol (THC) in hemp, cannabidiol (CBD) be non-cause
Cytotoxic activity ingredient, research experiment show its energy effective activation blood vessel, promote blood circulation.
Silymarin, the entitled Silymarin of foreign language are natural flavanolignan's class compounds, are from compositae plant
Natural active matter obtained from extracting in the dry fruit of milk thistle, main component are silibinin (silybin), different water
Fly Ji guest (isosilybim), silydianin (silydianin) and Silychristin (silychristin).Silymarin can be straight
Scavenger of ROS is connect, to anti peroxidation of lipid, the mobility of cell membrane is maintained, therefore there is very strong anti-oxidation function, protects
The effect that shield liver cell is destroyed from free radical outclass vitamin E, in addition, silymarin can promote the synthesis of protein,
Accelerate to manufacture new liver cell, or enable liver cell self-healing in damaged condition, therefore is referred to as " natural hepatoprotective agent ".
Vitamin A (VitaminA, abbreviation VA) is a kind of micronutrient needed by human, including two kinds of active hypotypes:
VA1Retinol and VA2Retinene, with VA1Based on, the present invention mainly uses physiology function of the VA in terms of maintaining eyesight, immune function
Can,
Vitamin E is well known antioxidant, is a kind of liposoluble vitamin, and therefore, it in air can not be steady for a long time
It is fixed to exist, there is very strong reproducibility, but its dosage is not that more more more vitamin is good yet, because it exists to other fat-soluble dimensions
Life is known as inhibition or antagonism, is found by experiment that, the suitable dosage of vitamin E is 0.9-1.5 parts.
Vitamin K is called coagulation vitamin, is one kind of vitamin, there are two types of natural vitamin K has been found that: a kind of
It is vitamin K1, another kind is farnoquinone, and vitamin K is widely present in Animal Liver, is that four kinds of blood coagulating proteins of synthesis must not
The factor that can lack, in the technical scheme, the presence of vitamin K can dexterously balance vitamin E physiological function and most preferably send out very much
It waves.
Beta carotene is one of carotenoid, and it is also most stable of natural pigment that it, which is most generally existing in nature,
Molecular structure is equivalent to the vitamin A of 2 molecules, and into after body, the effect of enzyme is passed through in liver and mucous membrane of small intestine, wherein
50% becomes vitamin A, there is nourishing liver and improving eyesight.Similar with lutein, it is also a kind of important antioxidant, the present invention
The reason of using beta carotene, the effect on the one hand clear liver and improved vision in view of it, skin can be stimulated by the other hand also allowing for it
Metabolism, promote blood circulation.
Lutein and zeaxanthin are only 2 Carotenoids in eyes, as antioxidant and photoprotection,
It can promote the regeneration of visual purple in retina cell (Rhodopsin), laser high myopia and detached retina can be prevented, and can increase
Into eyesight, protection eyesight, for numerous students and paperwork person, excessively the lutein levels caused by eye, which reduce, is also
Lead to one of myopia generation and the possible cause deepened, therefore, lutein is appropriately added in eyeshield composition, and cooperate micro-
Electric current stimulates eye degree to absorb, and the protection and reinforcement to eye eyesight have excellent facilitation.
Puerarin is also known as puerarin, is the isoflavonoid derivatives with coronary dilatation effect separated from Chinese medicament kudzu-vine root.
The technical program is advantageous in that it can act synergistically with plurality of raw materials component using Puerarin as main raw material components,
Has effects that nutrition calmness to optic nerve, and the saponins compound contained by it has reduction vascular resistence, improves microcirculation
Effect.
Golden cicada flower belongs to entomogenous fungi, and forming process is that the larva of cicada is infected by Cordyceps Militaris before cicada sprouts wings, is parasitic, when
When climatic environment is suitable for, the nutrition for absorbing polypide is converted to mycelium, and final polypide is fully taken up by mycelium and is only left one
A body, present biotechnology also can artificial culture cicada fungus, and then avoid the shortage of natural cicada fungus resource, Yi Jibao
Hinder the stability of product quality;The main chemical compositions of cicada extract are cicada fungus polysaccharide, there is antitumor, analgesia, calm work
With the skeptophylaxis active constituent furthermore contained in extract can coordinate auxiliary and play the visual fatigue and biological organs for adjusting eye
It is immune, at the same can also compatibility other compositions, avoid the generation of cutaneous anaphylaxis, and cicada fungus extraction is added in the technical scheme
For object other than containing certain antibacterial and immunologic enhancement, main function is that it can play degrading the channel and promoting blood circulation to eye
The effect of arteries and veins alleviates asthenopia and then eyesight is made to be protected and be reinforced.
There is the micro-current equipment at some assistant massaging acupuncture points on the market, the stimulation in acupuncture point between neuron can be enhanced and pass
It leads, releive local muscle and activating cell immunocompetence.
Comparing other similar product at present uses Chinese medicine as raw material, above-mentioned to be combined using analysis pure component as eyeshield
Object, not the quality discrepancy of Chinese medicine and use allergic problem, active constituent content will not be led to because of Chinese medicine place of production difference
Difference is big, can also avoid the wild effect generated between the different batches of medicinal material.
Inventor additionally provides one of a kind of eyeshield pad pasting, including above-mentioned eyeshield composition and support.
Preferably, the support is one of bacteria cellulose, mulberry silk, non-woven fabrics or aqueous gel.
According to the use habit different to eye patch, adoptable support base material can be bacteria cellulose, mulberry
One of silk, non-woven fabrics or aqueous gel, since the eye patch that the technical program obtains needs that microcurrent stimulating is cooperated to set
It is standby to carry out using preferred bacterium cellulose, bacteria cellulose is free from the native cellulose of any impurity, it has fine net
Network structure, higher mechanical strength, higher water suction and water retention property, good biocompatibility and biological degradability etc. are many
Unique performance is carried out in cooperation microcurrent stimulating equipment in use, absorbing water and protecting since its compactness and mechanical strength are very high
It is aqueous can be very strong so that the better effect of ocular absorption eye sticker film composition effective component.
Inventor additionally provides a kind of preparation method of eyeshield pad pasting, comprising the following steps:
Support is put into packaging bag, sterilization processing;
Above-mentioned eyeshield composition is added in the packaging bag, is vacuumized, is sealed to get eyeshield adhesive cover products.
Adhesive cover products are prepared as conventional method, and finished product is similar with hygenic towelette, eye mask and facial mask.It preferably protects in order to obtain
Wet and antioxidant effect extends storage term of validity, can take to fill to vacuumize carrying out plastic bag sealing preservation.
Be different from the prior art, above-mentioned technical proposal use with releive eye muscle, beautifying face and moistering lotion effect ingredient and
Synergistic effect preparation eyeshield composition and its eye patch between the active constituent of eyeshield, compared with existing product, have with
Lower advantage:
1, raw material components are pure, are not in that Chinese medicine place of production difference causes active constituent content difference big, can also avoid
The pharmacological property wild effect generated between different batches Chinese medicine, to reach the scientific compatibility between ingredient;
2, synergistic effect makes in the eye sticker film composition containing small molecule active nutrients needed for eye between raw material components
Matter cicada fungus polysaccharide, beta glucan, acidic polysaccharose, neutral heteropolysaccharide. and acid oligosaccharides provide sufficient easily suction for eyelid reconstruction
The nutrition of receipts provides energy source abundant for eye circumference cell repair;
3, effective component cannabidiol, taurine and the Puerarin of the cannabis oil of specificity addition are to calm optic nerve, rush
There is effect unique into microcirculation;
4, the enhancing ocular immune power of the strong anti-oxidation function binding function component of vitamin E, lutein and silymarin
Effect, so that eye sticker film composition is had the function of traditional eye patch unexistent prevention and myopia correction;
5, the ingredient between alginic acid and oligosaccharide and dosage pass through reasonable compatibility, play to other active components good
Stabilization, while it can be with moisturizing and anti-inflammatory antibacterial;
6, eye patch combination micro-current equipment can be promoted into effective component with the special efficacy that micro-current imports
It absorbs and utilizes, enhance prevention, correction and the effect of restoring ocular cell.
Specific embodiment
Technology contents, construction feature, the objects and the effects for detailed description technical solution, below in conjunction with specific reality
Example is applied to be explained in detail.
Drug ingedient or raw material involved in embodiment can be acquired by conventional route, and wherein alginic acid is
It handles to obtain through reverse osmosis membrane technology by the sodium alginate that market is purchased, eyesight detection is using conventional visual chart and combines detection
The sight tester of detecting eye diopter carries out.
Embodiment one
Prepare a kind of eyeshield pad pasting
Commercially available analysis pure sodium alginate is handled through reverse osmosis membrane technology, obtains analytically pure alginic acid;
Vitamin A 18g, vitamin K 3g are measured, by unstable vitamin A, vitamin K by first with cyclodextrin packet
It closes, forms inclusion compound, measure beta glucan 9g, alginic acid 35g, dried tremella extract 4g, chitosan oligosaccharide 15g, beta carotene 13g, big
Sesame oil 2g, taurine 12g, Puerarin 12g, cicada extract 0.7g and deionized water 257.3g, then the above material is placed in
In agitator tank, 60min is stirred at a temperature of 35-50 DEG C, is cooled to room temperature, then by inclusion compound, vitamin E 12g, silymarin
20min is stirred in 4g and lutein 4g addition together, adjusts revolving speed to 2500rpm, homogeneous 30min with the homogenizer of power 15kw,
Discharging obtains eye sticker film composition after standing, after handling through filter membrane, is sterilized, obtains eye sticker film composition finished product.
Bacteria cellulose substrate is cut into the pad pasting for meeting eye circumference shape, packaging bag is put it into and carries out sterilization processing,
Eye sticker film composition finished product 20g obtained above is filled into the packaging bag after sterilization, vacuumizes and seals to get eyeshield is arrived
Adhesive cover products.
Comparative example one
Prepare a kind of eyeshield pad pasting A
What is different from the first embodiment is that in addition to the additive amount of cicada extract and Puerarin is changed to 0.6g and 20g respectively,
Other process conditions and formula additive amount are the same as example 1, and eyeshield pad pasting A is prepared.
Comparative example two
Prepare a kind of eyeshield pad pasting B
What is different from the first embodiment is that in addition to the additive amount of dried tremella extract and Puerarin is changed to 6g and 20g respectively,
His process conditions and formula additive amount are the same as example 1, and eyeshield pad pasting B is prepared.
Experimental example one
Test method: with 5 ages it was 25 one full year of life, is engaged in similar professional (based on computer paperwork), initial eyesight
The women of identical (being 1.2) is as test object.Subject is divided into 5 groups, preceding 3 groups of subjects in the same manner periocualr skin,
Application embodiment one, eyeshield pad pasting corresponding to comparative example one and comparative example two respectively before three evenings of every weekly selection sleep, the 4th by
Examination person is set as that blank group is without any processing, and the eyeshield pad pasting of the 5th subject's embodiment one cooperates microcurrent stimulating, stimulation
Method is stops 3min after every 2 minutes microcurrent stimulatings, and the time of deposited eye patch is 25min every time, and 6 months by a definite date, each
The moon carries out tracking and testing to subject, and test result is as shown in table 1:
Eyesight result data after 1 25 one full year of life of table is for women
Eyeshield pad pasting | First month | Second month | Third month | Four month | Five month | Six month |
Embodiment one | 1.2 | 1.2 | 1.2 | 1.2 | 1.5 | 1.5 |
Comparative example one | 1.2 | 1.2 | 1.2 | 1.2 | 1.5 | 1.5 |
Comparative example two | 1.2 | 1.2 | 1.2 | 1.2 | 1.2 | 1.5 |
Blank group | 1.2 | 1.2 | 1.2 | 1.2 | 1.0 | 1.0 |
One+micro-current of embodiment | 1.2 | 1.2 | 1.5 | 1.5 | 1.5 | 1.5 |
Embodiment two
Prepare a kind of eyeshield pad pasting
Commercially available analysis pure sodium alginate is handled through reverse osmosis membrane technology, obtains analytically pure alginic acid;
Vitamin A 20g, vitamin K 2g are measured, they are included with cyclodextrin, forms inclusion compound, measures β-Portugal
Glycan 10g, alginic acid 20g, dried tremella extract 3g, chitosan oligosaccharide 18g, 15'-dioxygenase g, cannabis oil 1g, taurine 11g, pueraria lobata
Plain 15g, cicada extract 0.8g and deionized water 284.2g, the above material is placed in agitator tank, in 35-60 DEG C of temperature
Lower stirring 60min, is cooled to room temperature, then by inclusion compound obtained above, vitamin E 11g, silymarin 5g and lutein 3g
20min is stirred, revolving speed is adjusted with the homogenizer of power 15kw and arrives 2500rpm, homogeneous 30min discharges after standing and obtains eye patch
Composition after handling through filter membrane, is sterilized, and eye sticker film composition finished product is obtained.
By aqueous gel base material cutting at the pad pasting for meeting eye circumference shape, puts it into packaging bag and carry out sterilization processing, it will
Eye sticker film composition finished product 20g obtained above is filled into the packaging bag after sterilization, is vacuumized and is sealed to get eye paste is arrived
Film product.
Comparative example three
Prepare a kind of eyeshield pad pasting C
Unlike embodiment two, except the composition prepared without filter membrane processing in addition to, other process conditions and
It is identical as embodiment two to be formulated additive amount, eyeshield pad pasting C is prepared.
Comparative example four
Prepare a kind of eyeshield pad pasting D
Unlike embodiment two, except adjusting revolving speed to 3000rpm, homogeneous 20min with the homogenizer of power 10kw, it
Outside, other process conditions and formula additive amount are identical as embodiment two, and eyeshield pad pasting D is prepared.
Experimental example two
Test method: using Joe college that 5 ages are 20 one full year of life (eyesight is 1.0) as test object.It will be tested
Person is divided into 5 groups, preceding 3 groups of subjects in the same manner before periocualr skin, three evenings of every weekly selection sleep respectively application embodiment two, compare
Eyeshield pad pasting corresponding to example three and comparative example four, it is without any processing that the 4th subject is set as blank group, the 5th subject
Cooperate microcurrent stimulating with the eyeshield pad pasting of embodiment two, stimulating method is stops 2min after every 1 minute microcurrent stimulating, every time
The time for applying eye patch is 20min, and 6 months by a definite date, every month carried out tracking and testing, test result such as 2 institute of table to subject
Show:
The rear eyesight result data of 2 20 one full year of life of table Joe college
Eyeshield pad pasting | First month | Second month | Third month | Four month | Five month | Six month |
Embodiment two | 1.0 | 1.0 | 1.0 | 1.2 | 1.2 | 1.2 |
Comparative example three | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.2 |
Comparative example four | 1.0 | 1.0 | 1.2. | 1.2 | 1.2 | 1.2 |
Blank group | 1.0 | 1.0 | 1.0 | 1.0 | 0.8 | 0.8 |
Two+micro-current of embodiment | 1.0 | 1.0 | 1.2 | 1.2 | 1.2 | 1.5 |
From the experimental data in two tables above it is found that same age bracket, identical gender, occupation and living habit it is tested
Person matches when receiving the eyeshield pad pasting of distinct methods preparation according to the eyeshield pad pasting that embodiment one and two method of embodiment are prepared
It is best to the health-care effect of subject's eyesight to close microcurrent stimulating, is secondly embodiment one, comparative example one, comparative example four obtain
Eyeshield pad pasting is also shown in addition to excellent sight protectio and enhancing function, and two groups of experiments show the eyesight of blank group with work
Make, learn, visual impairment caused by the bad habit with eye in life, but for same group of subject, having used eyeshield pad pasting
It is repaired and is prevented, eye eyesight is able to maintain or makes moderate progress.The stimulation of micro-current is to subject's periocualr skin to shield
The absorption of eye combination active substances has significant facilitation, simultaneously because the eyeshield composition other than comparative example three exists
It is handled through filter membrane in preparation process, active material molecules group is minimum, easily absorbs by eye peripheral point, has spy to human liver
Fixed nourishes effect further increases ocular immune power.
It is appreciated that the substrate of eyeshield pad pasting can be substituted for according to conventional production in above-described embodiment one and embodiment two
Mulberry silk or non-woven fabrics, but the compactness of both substrates and weaker compared with bacteria cellulose and aqueous gel to fungistatic effect.
There is good functional active components compatibility, and processed between the raw material components that the technical program is selected
In journey unstable vitamin A and vitamin K are carried out by inclusion processing using cyclodextrin in advance, then passes through relatively mild technique item
Part makes this oil-soluble ingredient of cannabis oil first form surface active ingredient with alginic acid-chitosan oligosaccharide, the oil after carrying out homogeneous
Soluble components can be formed in conjunction with good lipophilicity with skin, in homogenizer after emulsifying, be filled into shield
When in the packaging of eye patch support, it is equably coated with or is penetrated into support, extra eyeshield pad pasting will not be generated in application
With application slow release, effect is fine for composition liquid drip, vitamin A and vitamin K.
It should be noted that being not intended to limit although the various embodiments described above have been described herein
Scope of patent protection of the invention.Therefore, it based on innovative idea of the invention, change that embodiment described herein is carried out and is repaired
Change or the equivalent structure or equivalent process transformation made by using the contents of the present specification, directly or indirectly by the above technology
Scheme is used in other related technical areas, is included within scope of patent protection of the invention.
Claims (5)
1. a kind of eyeshield composition, which is characterized in that by weight percentage, including following components:
2. eyeshield composition according to claim 1, which is characterized in that by weight percentage, including following components:
3. a kind of eyeshield pad pasting, which is characterized in that including eyeshield composition of any of claims 1 or 2 and support.
4. eyeshield pad pasting according to claim 3, which is characterized in that the support is bacteria cellulose, mulberry silk, nothing
One of woven fabric or aqueous gel.
5. a kind of preparation method of eyeshield pad pasting as claimed in claim 4, which comprises the following steps:
Support is put into packaging bag, sterilization processing;
Eyeshield composition of any of claims 1 or 2 is added in the packaging bag, is vacuumized, sealing is to get the production of eyeshield pad pasting
Product.
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