CN109283351A - Automatic coagulation analyzer - Google Patents
Automatic coagulation analyzer Download PDFInfo
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- CN109283351A CN109283351A CN201811344152.8A CN201811344152A CN109283351A CN 109283351 A CN109283351 A CN 109283351A CN 201811344152 A CN201811344152 A CN 201811344152A CN 109283351 A CN109283351 A CN 109283351A
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- cup
- reaction cup
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The present invention relates to a kind of automatic coagulation analyzer, including shell, reaction cup feed system, sample and reagent delivery system, detection system, sample bit, reagent position, useless cup accommodating mechanism, scanning system and host system are provided in shell；Reaction cup feed system receives reaction cup into rim of a cup from outside by shell, so that reaction cup is delivered to detection system；Sample and reagent delivery system are arranged to sample and reagent being delivered to detection system from sample bit and reagent position；Useless cup accommodating mechanism is arranged to the reaction cup that storage detection finishes from detection system；Host system includes human-computer interaction module and control module.Each function system subregion of the invention is reasonable, and the operation of each system efficiently uses space without additional configuration computer by an independent host integrated control, and automatic detection operation is more smooth, and detection speed is fast, and simple and quick, small in size, failure rate is low.
Description
Technical field
The invention belongs to medical instruments fields, and in particular to a kind of automatic coagulation analyzer.
Background technique
With the raising of medical technology, coagulation analysis has been analysis means conventional in hospital.Blood coagulation analyzer includes
Full automatic blood coagulation analyzer and automanual blood coagulation analyzer.Automanual blood coagulation analyzer need to expend biggish manpower at
This, the testing time is long, does not adapt to test sample amount and mostly requires with quickly test etc..And full automatic blood coagulation analyzer is suitble to greatly
Measure the test of sample.
But there is also some defects, the implementation methods of automatic coagulation analyzer for current automatic coagulation analyzer
It is then blood sample and test agent are reinjected using fixed partition, to complete entire automatic detection process, leads to multiple kinetic systems
System, which intersects, frequently to be run between fixed partition, causes the test speed of entire instrument slow in this way, and whole system is numerous and jumbled, no
It is easy to control, high failure rate.
The information for being disclosed in the background of invention technology segment is merely intended to deepen the reason to general background technique of the invention
Solution, and it is known to those skilled in the art existing to be not construed as recognizing or imply that the information is constituted in any form
Technology.
Summary of the invention
The purpose of the present invention is to provide a kind of automatic coagulation analyzer, each function system subregion is reasonable, each system
The operation of system efficiently uses space, automatic detection operation without additional configuration computer by an independent host integrated control
More smooth, detection speed is fast.
The purpose of the present invention is what is be achieved through the following technical solutions:
A kind of automatic coagulation analyzer, including shell are provided with reaction cup feed system, sample and examination in the shell
Agent transportation system, detection system, sample bit, reagent position, useless cup accommodating mechanism, scanning system and use for scanned samples information
In the host system for the work for controlling the automatic coagulation analyzer；The reaction cup feed system by the shell into
Rim of a cup receives reaction cup from outside, so that reaction cup is delivered to the detection system；The sample and reagent delivery system are set
It is set to and sample and reagent is delivered to the detection system from the sample bit and the reagent position；The useless cup accommodating mechanism is set
It is set to the reaction cup that storage detection finishes from the detection system；The host system includes human-computer interaction module and control mould
Block.
Preferably, the reaction cup feed system, the detection system, the sample bit and the reagent position are arranged at
The side of the detection system, the sample bit and the examination is arranged in the lower part of the shell, the reaction cup feed system
The other side of the detection system opposite with the reaction cup feed system, the sample and reagent delivery system is arranged in agent position
System is arranged in the top of the shell and can move between the detection system and the sample bit and the reagent position.
Preferably, the reaction cup feed system include delivery chute, link slot, the storage cup slot being arranged on storage cup bottom plate,
Reaction cup pushing mechanism and push rod；The link slot is arranged between the delivery chute and the storage cup bottom plate；The delivery chute
First end the outside of the shell is reached into rim of a cup to receive reaction cup by the shell, the of the delivery chute
Two ends are vertically connected with the link slot, and conveyer belt is equipped in the delivery chute so that reaction cup is defeated from the first end
It send to the second end；The storage cup slot is slidably connected on storage cup bottom plate described to be parallel on the storage cup bottom plate
Link slot sliding, when the storage cup slot slides into the position of the close link slot of the storage cup bottom plate, the storage cup slot
It is connected with the link slot；The reaction cup pushing mechanism is described defeated will be located at close to the second end setting of the delivery chute
The reaction cup at the second end of slot is sent to be pushed in the storage cup slot via the link slot；The push rod is close to the storage cup
Slot setting is pushed in the detection system with the reaction cup being placed in the storage cup slot.
Preferably, the conveyer belt in the delivery chute passes through the first stepping motor driven, the reaction cup pushing mechanism packet
Include supporting plate, the transmission belt being arranged on the supporting plate and the reaction cup catch bar driven by the transmission belt, the transmission
Band is driven by second stepper motor, and the transmission belt extends to the storage cup bottom plate above the second end of the delivery chute
The position that is connected with the link slot above, the reaction cup catch bar is by connection frame with the transmission band connection to pass through
Reaction cup is pushed in the storage cup slot by the reaction cup catch bar from the delivery chute.
Preferably, reaction cup inductor is provided at the second end of the delivery chute to incude whether reaction cup reaches institute
It states at the second end of delivery chute；There are two position sensors to be respectively induced reaction cup catch bar for setting at the top of the supporting plate
Whether initial position and result position are reached, and the initial position is that reaction cup catch bar starts reaction when driving a reaction cup
Position where cup catch bar, the result position be reaction cup catch bar when reaction cup is pushed in the storage cup slot described in
Position where reaction cup catch bar.
Preferably, the storage cup bottom plate is equipped with sliding rail, and the storage cup trench bottom is equipped with the sliding slot cooperated with the sliding rail,
The storage cup slot by third stepping motor driven, the storage cup slot be connected with the motor driving plate of the third stepper motor with
It is slided on the storage cup bottom plate.
Preferably, it is moved for the reaction cup in the storage cup slot to be pushed to the push rod in detection system by connection
Motion block is slidably connected with the motor driving plate, and the push rod connects with the connection movable block and can be relative to described
Movable block movement is connected, the push rod is driven by the spindle motor connected with the connection movable block, the storage cup slot, institute
Connection movable block, the push rod and the spindle motor are stated integrally by the motor driving plate of the third stepper motor
Driving along the storage cup bottom plate integrally to move.
Preferably, the detection system includes detection support, the heating bottom plate being connected at the top of the detection support and company
Connect the sense channel on the heating bottom plate, the sense channel be connected with the reaction cup feed system by slideway so that
Reaction cup enters the sense channel from the reaction cup feed system, and the first side of the sense channel is provided with the electricity that shines
Road plate is with using the sample and reagent in photo-irradiation reaction cup, second side opposite with first side of the sense channel is set
Be equipped with detection circuit board in reaction cup sample and reagent carry out light data acquisition, the heating bottom plate be equipped with overheat guarantor
Shield switch is to control within a predetermined range the temperature of the heating bottom plate.
Preferably, the first side of the sense channel and second side are respectively arranged with luminous circuit board lid and detection circuit board
Lid.
Preferably, it is anti-in channel slot to fix to be equipped with stationary spring for the inner sidewall of the channel slot of the sense channel
Answer cup.
Preferably, the luminous circuit board is fixed on the lateral wall of the first side of the sense channel, and the detection is logical
The side wall of first side in road is equipped with loophole.
Preferably, the bottom position corresponding with sense channel of the heating bottom plate is equipped with heating sheet.
Preferably, the detection circuit board is arranged on the lateral wall of second side of the sense channel.
Preferably, the sample and reagent delivery system include first movement arm, the second moving arm, specimen needle and reagent
Needle, second moving arm are slidably connected on the first movement arm with can be relative to the first movement arm described
It is moved between sample bit and the reagent position, the specimen needle is connected to the one of the close sample bit of second moving arm
Side, the reagent needle are connected to the side close to the reagent position of second moving arm, the specimen needle and the reagent
Needle can be moved up and down relative to second moving arm, and the first movement arm is slidably connected by sliding panel described
So that the first movement arm is moved along the transverse direction of the posterior medial wall on the posterior medial wall of shell, to drive institute
It states specimen needle and the reagent needle moves between the sample bit and the reagent position and the detection system.
Preferably, further comprise cleaning position for cleaning the specimen needle and the reagent needle, hull outside it is clear
Washing lotion pipeline enters shell by the pipe interface on the shell to connect with the specimen needle and the reagent needle, thus
The specimen needle and the reagent needle are cleaned in the cleaning position.
Preferably, the reagent needle is equipped with pre-heating module to preheat to the reagent needle.
Preferably, the useless cup accommodating mechanism includes useless cup storage box, and the useless cup storage box is set by storage box drawer
It sets in the lower part of the housing at the position of the detection system.
It preferably, further comprise wireless communication module to communicate to carry out testing result output with other equipment.
Preferably, the upper part of the housing is equipped with the cover that can open the inner space of the shell.
The invention has the benefit that
1. each function system subregion of automatic coagulation analyzer of the invention is reasonable, the operation of each system passes through list
An only host integrated control efficiently uses space without additional configuration computer, and automatic detection operation is more smooth, detection speed
Degree is fast, detects speed PT (T/h) >=360T/h, simple and quick, small in size, failure rate is low.
2. full-automatic sample-adding, fluid path is simple, and reagent needle set has individual heating module, can carry out pre-add to reagent needle
Heat, therefore reagent does not need individually to be incubated for before entering reagent needle, saves reagent dosage, improves detection accuracy and detection speed
Degree.
3. detection system thermostatic control within the scope of 37 DEG C ± 5 DEG C, improves detection accuracy.
4. reaction cup feed system uses one cup bulk loading, it is conducive to save the cost, into cup spaces compact, when convenient for detection
Sequence design, examines project planning more flexible.
5. complete machine only uses a set of detection module, at low cost, high reliablity；Cover current all detection methods: freezing method, hair
Color substrate method, immunoturbidimetry, latex agglutination；Greatly improve group item visual inspection degree of testing the speed.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of automatic coagulation analyzer described in the embodiment of the present invention；
Fig. 2 is the structural schematic diagram of reaction cup feed system described in the embodiment of the present invention；
Fig. 3 is motor driving plate described in the embodiment of the present invention, storage cup slot, push rod, connection movable block and spindle motor
Attachment structure schematic diagram；
Fig. 4 is the structural schematic diagram of detection system described in the embodiment of the present invention；
Fig. 5 is the main view of one of sense channel in detection system described in the embodiment of the present invention.
Description of symbols:
1- reaction cup feed system；2- touch display screen；3- first movement arm；The second moving arm of 4-；5- pipeline support；6-
Sliding panel；7- specimen needle；8- reagent needle；9- detection system；The cleaning position 10-；11- room temperature reagent position；12- cools down reagent position；13-
Pipe interface；14- scanning system；The common sample bit of 15-；16- emergency treatment sample bit；17- gives up cup storage box；18- storage box drawer；
19- shell；
101- reaction cup means for correcting；102 conveyer belts；103- delivery chute；104- reaction cup；The first stepper motor of 105-；
106- reaction cup inductor；107- guiding axis；108- position sensor；109- reaction cup catch bar；110- link slot；111-
Two stepping motor；112- storage cup bottom plate；113- third stepper motor；114 storage cup slots；115- spindle motor；116- push rod；117-
Motor driving plate；118- gib block；119- connection movable block；The first track of 120-；The second track of 121-；122- shaft；123-
Driving plate connector；
901- heats bottom plate；902- overheat switch；903- luminous circuit board lid；904- luminous circuit board；905- is sliding
Road；906- sense channel；907- detection circuit board；908- detection circuit board lid；909- stationary spring；910- heating sheet；
911- circuit main board；912- circuit board.
It is to be appreciated that appended attached drawing is not proportionally drawn, and merely to illustrating each of basic principle of the invention
The suitably simplified technique of painting of kind feature.The specific design feature of invention disclosed herein include for example specific size, direction,
Position and shape will be partly determined by the specific application and use environment.
In appended multiple attached drawings, same or equivalent component (element) is with the index of identical appended drawing reference.
Specific embodiment
Combined with specific embodiments below and respective drawings the invention will be further described.
As shown in Figure 1, automatic coagulation analyzer described in the embodiment of the present invention, including shell 19, the interior setting of shell 19
There are reaction cup feed system 1, sample and reagent delivery system, detection system 9, sample bit, reagent position, useless cup accommodating mechanism, use
In the scanning system 14 of scanned samples information and the host system of the work for controlling automatic coagulation analyzer of the invention；
The reaction cup feed system 1 receives reaction cup into rim of a cup from outside by the shell 19, so that reaction cup is delivered to
The detection system 9；The sample and reagent delivery system are arranged to for sample and reagent being delivered to from sample bit and reagent position
The detection system 9；Useless cup accommodating mechanism is arranged to the reaction cup that storage detection finishes from detection system 9；Host system packet
Include human-computer interaction module and control module.
Wherein, the reaction cup feed system 1, the detection system 9, the sample bit and the reagent position are arranged at
The side of the detection system 9, the sample bit and institute is arranged in the lower part of the shell 19, the reaction cup feed system 1
State the other side that the detection system 9 opposite with the reaction cup feed system 1 is arranged in reagent position, the sample and reagent
Transportation system is arranged in the top of the shell 19 and can be in the detection system 9 and the sample bit and the reagent position
Between move.
In this example, human-computer interaction module is the touch display screen 2 of human-computer interaction.
Each function system subregion of automatic coagulation analyzer of the invention is reasonable, and the operation of each system passes through independent
One host integrated control efficiently uses space without additional configuration computer, and automatic detection operation is more smooth, detects speed
Fastly, speed PT (T/h) >=360T/h is detected, simple and quick, small in size, failure rate is low.
The sample bit of automatic coagulation analyzer of the invention includes emergency treatment sample bit 16 and common sample bit 15, host system
The control module of system can be according to the blood sample of the setting priority processing emergency treatment sample bit 16 of host system.Scan module is close to sample bit
Setting passes through scanning system 14 and carries out information scanning before putting samples into sample bit.
Reagent position of the invention includes room temperature reagent position 11 and cooling reagent position 12, and being required according to the different temperatures of reagent can
Corresponding reagent position is put into selection.Cooling reagent position 12, which is equipped with refrigerating module, may insure the temperature control of cooling reagent position 12
It is being less than or equal to 10 DEG C.
As shown in Figures 2 and 3, reaction cup feed system 1 of the invention exists including delivery chute 103, link slot 110, setting
Storage cup slot 114, reaction cup pushing mechanism and push rod 116 on storage cup bottom plate 112, the setting of link slot 110 is in delivery chute 103 and storage
Between bottom of a cup plate 112；The first end of delivery chute 103 reaches the outside of shell 19 into rim of a cup to receive instead by shell 19
Cup 104 is answered, the second end of delivery chute 103 is vertically connected with link slot 110, and conveyer belt 102 is equipped in delivery chute 103 to incite somebody to action
Reaction cup 104 is delivered to the second end from first end；Storage cup slot 114 is slidably connected on storage cup bottom plate 112 in storage cup
The sliding of link slot 110 is parallel on bottom plate 112, when storage cup slot 114 slides into the position of the close link slot 110 of storage cup bottom plate 112
When setting, storage cup slot 114 is connected with link slot 110；Reaction cup pushing mechanism close to delivery chute 103 the second end setting with by position
Reaction cup 104 at the second end of delivery chute 103 is pushed in storage cup slot 114 via link slot 110, and push rod 116 is close
The setting of storage cup slot 114 is pushed in detection system 9 with the reaction cup 104 being placed in storage cup slot 114.
It is anti-into in system to correct that reaction cup means for correcting 101 is equipped in this example, at the first end of delivery chute 103
Cup 104 is answered, while 103 bottom of delivery chute is equipped with the gib block 118 of the length direction along delivery chute 103,104 bottom of reaction cup is set
There is the guide groove with the gib block 118 cooperation, reaction cup 104 can be enable by the cooperation of gib block 118 and guide groove
Be constantly fed in delivery chute 103, be not in during transportation reaction cup topple over or skew.In delivery chute 103
Conveyer belt 102 pass through the first stepper motor 105 drive.
Wherein, the reaction cup pushing mechanism includes supporting plate, the transmission belt being arranged on supporting plate and is driven by transmission belt
Dynamic reaction cup catch bar 109, transmission belt are driven by second stepper motor 111, the second end of the transmission belt from delivery chute 103
Top extends to above the position of storage cup bottom plate 112 being connected with the link slot 110, and reaction cup catch bar 109 passes through connection
Reaction cup to be pushed in storage cup slot 114 by frame and the transmission band connection by reaction cup catch bar 109 from delivery chute 103.
Wherein, reaction cup inductor 106 is provided at the second end of the delivery chute 103 to incude whether reaction cup arrives
Up at the second end of the delivery chute 103；There are two position sensors 108 to be respectively induced instead for setting at the top of the supporting plate
Answer whether glass catch bar 109 reaches initial position and result position, the initial position is that reaction cup catch bar 109 starts to push
Position when reaction cup where the reaction cup catch bar 109, the result position are that reaction cup catch bar 109 pushes away reaction cup
Position when moving in the storage cup slot 114 where the reaction cup catch bar 109.
The guiding axis 107 parallel with transmission belt is additionally provided in this example, on supporting plate, guiding axis 107 is passed through and pushed away with reaction cup
The connection frame that lever 109 connects, enables connection frame to move along guiding axis 107, to carry out to reaction cup catch bar 109
Guiding.
Wherein, storage cup bottom plate 112 is equipped with sliding rail, and 114 bottom of storage cup slot is equipped with the sliding slot cooperated with the sliding rail, storage cup
Slot 114 is driven by third stepper motor 113,117 phase of motor driving plate of storage cup slot 114 and the third stepper motor 113
Even at the position that is connected on the storage cup bottom plate 112 with the link slot 110 and on the storage cup bottom plate 112 with the inspection
Examining system 9 slides between corresponding position.
Reaction cup is delivered to the second end from the first end of delivery chute 103, when reaction cup inductor 106 senses reaction
When cup has arrived at the second end of delivery chute 103, opened under the drive of transmission belt in the reaction cup catch bar 109 of initial position
The direction driving a reaction cup to begin to link slot 110, at this moment storage cup slot 114 has slided on storage cup bottom plate 112 and link slot
At the position of 110 linkings, 109 driving a reaction cup of reaction cup catch bar is via link slot 110 until pushing it to storage cup slot 114
In.Position sensor 108 senses that reaction cup catch bar 109 has arrived at the position that reaction cup is pushed completely into storage cup slot 114,
Then control module control reaction cup catch bar 109 stops pushing and being resetted (back to initial position to next to push
A reaction cup is prepared).The storage cup slot 114 for being mounted with reaction cup slides into position corresponding with detection system 9 along storage cup bottom plate 112
It sets, after reaction cup is pushed into detection system 9, it is waiting that unloaded storage cup slot 114 returns position being connected with link slot 110 etc.
Receive next reaction cup.
Reaction cup feed system 1 uses one cup bulk loading, is conducive to save the cost, into cup spaces compact, when convenient for detection
Sequence design, examines project planning more flexible.
In this example, 110 bottom of link slot has to the inclined gradient of storage cup bottom plate 112, to keep reaction cup more suitable
Freely enter storage cup slot 114.
As shown in figure 3, for the push rod 116 that the reaction cup in storage cup slot 114 is pushed in detection system 9 to be passed through connection
Movable block 119 is slidably connected with motor driving plate 117, push rod 116 with connect movable block 119 connection and can relative to even
It is mobile to connect movable block 119, push rod 116 by being driven with the spindle motor 115 that movable block 119 connects connect, storage cup slot 114,
Movable block 119, push rod 116 and spindle motor 115 is connected integrally to drive by the motor driving plate 117 of third stepper motor 113
It moves integrally to be moved along storage cup bottom plate 112.
The lead screw of spindle motor 115 is connected with movable block 119 is connect, on the driving plate connector 123 of motor driving plate 117
Equipped with the first track 120, the side for connecting movable block 119 is equipped with the first track groove cooperated with the first track 120, spindle motor
115 drive connection movable blocks 119 are slided along the first track 120 to drive push rod 116 along the reaction cup released in storage cup slot 114
Direction is mobile；The lower part of push rod 116 is equipped with second track 121 vertical with first track 120, connection movable block 119
Bottom is equipped with the second track groove cooperated with the second track 121, and push rod 116 is slidably connected with movable block 119 is connect so as to push away
Bar 116 can be slided relative to connection movable block 119.
Push rod 116 is equipped with the shaft 122 parallel with the second track 121, and connection movable block 119 is equipped with and shaft 122
The mounting hole matched, shaft 122 pass through mounting hole and can the axial direction in mounting hole along shaft 122 move, axis
Bar 122 is equipped with positioned at push rod 116 and connects the spring (not shown) between movable block 119.
For push rod 116 in order to push the reaction cup in storage cup slot 114, push rod 116 is arranged to the notch with storage cup slot 114
Alignment, motor driving plate 117 drive storage cup slot 114 and push rod 116 together to link slot 110 it is mobile make storage cup slot 114 with
Link slot 110 is aligned, and at this moment push rod 116 would interfere with link slot 110 and mutually contradict, as motor driving plate 117 drives
Storage cup slot 114 is mobile to link slot 110, and link slot 110 will push push rod 116 to close to the direction of connection movable block 119, pushes away
Bar 116 is mobile to connection movable block 119, and spring is compressed, when storage cup slot 114 has loaded reaction cup to separate link slot 110
Direction is mobile, and push rod is restored to the position being aligned with the notch of storage cup slot under the action of the restoring force of spring.
As shown in Figure 4 and Figure 5, the detection system 9 includes detection support, the heating bottom plate being connected at the top of detection support
901 and the sense channel 906 that is connected on heating bottom plate 901, the sense channel 906 pass through slideway 905 and the reaction cup
Feed system 1 is connected so that reaction cup enters the sense channel 906 from the reaction cup feed system 1, and the detection is logical
First side in road 906 is provided with luminous circuit board 904 to utilize the sample and reagent in photo-irradiation reaction cup, the sense channel
906 second side opposite with first side be provided with detection circuit board 907 in reaction cup sample and reagent carry out
Light data acquisition, the heating bottom plate 901 are equipped with overheat switch 902 to control the temperature of the heating bottom plate 901
Within a predetermined range.Thermostatic control improves detection accuracy within the scope of 37 DEG C ± 5 DEG C.
First side of sense channel 906 and second side are respectively arranged with luminous circuit board lid 903 and detection circuit board lid
908。
The inner sidewall of the channel slot of sense channel 906 is equipped with stationary spring 909 to fix the reaction cup in channel slot.
Luminous circuit board 904 is fixed on the lateral wall of the first side of the sense channel 906, and the of sense channel 906
The side wall of side is equipped with loophole (not shown).
Detection circuit board 907 is arranged on the lateral wall of second side of sense channel 906.
Circuit main board 911 and circuit board 912 for detection system 9 are arranged in detection support.
In this example, there are four sense channels 906 for setting in detection system 9, thus once can at most put in detection system 9
Four reaction cups are set, are set in each reaction cup there are four check bit, a reaction cup can fill four samples, therefore, detection system
System 9 once at most can detecte 16 samples.
The bottom position corresponding with sense channel 906 of bottom plate 901 is heated equipped with heating sheet 910, set in this example there are four
Sense channel 906, the then bottom for heating bottom plate 901 are equipped with corresponding four heating sheets 910.
The quantity that sense channel has been illustrated in this example is four, but the quantity of sense channel is without being limited thereto, Ke Yigen
The quantity of sense channel is selected according to actual needs.
Detection system 9 is connected by slideway 905 with reaction cup feed system 1, and slideway 905 includes two parts, close to anti-
Answer gradient possessed by the part of glass feed system 1 that reaction cup is enable preferably to be transitioned into detection system 9, slideway
905 more easily enter reaction cup in sense channel 906 close to the part of sense channel 906, into the anti-of sense channel 906
It answers cup to carry out being loaded this and reagent by sample and reagent delivery system, is irradiated by LED light, then carry out light data acquisition
To obtain testing result.Luminous circuit board 904 is light emitting diode (LED) circuit board, utilizes LED light and filter plate, Mei Gejian
Location all supports multi-wavelength detection, improves detection anti-interference ability and accuracy.
As shown in Figure 1, the sample and reagent delivery system include first movement arm 3, the second moving arm 4,7 and of specimen needle
Reagent needle 8, second moving arm 4 are slidably connected on the first movement arm 3 with can be relative to the first movement
Arm 3 moves between the sample bit and the reagent position, and the specimen needle 7 is connected to the close institute of second moving arm 4
The side of sample bit is stated, the reagent needle 8 is connected to the side close to the reagent position of second moving arm 4, the sample
This needle 7 and the reagent needle 8 can be moved up and down relative to second moving arm 4, and the first movement arm 3 passes through sliding
Plate 6 is slidably connected on the posterior medial wall of the shell 19 so that the first movement arm 3 is along the posterior medial wall
Transverse direction is mobile, so that specimen needle 7 and reagent needle 8 be driven to move between sample bit and reagent position and detection system 9.
First movement arm 3 is fixed on sliding panel 6, and sliding panel 6 is slidably connected with the sliding rail on 19 posterior medial wall of shell,
In Fig. 1, first movement arm 3 slides in the lateral direction, and the second moving arm 4 can also pass through the cooperation of sliding rail and sliding slot and the
One moving arm 3 connection, to make the second moving arm 4 slide relative to first movement arm 3, before and after first movement arm 3 is in Fig. 1
Across sample bit and reagent position, the second moving arm 4 moves length on direction in the longitudinal direction relative to first movement arm 3,
It is namely moved between sample bit and reagent position, so that specimen needle 7 is sampled this in sample bit by the movement of the second moving arm 4
Reagent needle 8 takes reagent in reagent position, so that specimen needle 7 and reagent needle 8 is come detection system by the movement of first movement arm 3
9 are discharged to sample and reagent in detection system 9 to detect.Specimen needle 7 and reagent needle 8 can be mobile relative to second
Arm 4 is moved up and down to facilitate and sample this and reagent and discharge sample and reagent.
As shown in Figure 1, automatic coagulation analyzer of the invention further comprises for cleaning the specimen needle 7 and described
The cleaning position 10 of reagent needle 8, the cleaning liquid pipeline outside shell 19 enter shell by the pipe interface 13 on the shell 19
19 with the specimen needle 7 and the reagent needle 8 to connect, thus in the cleaning position 10 to the specimen needle 7 and the reagent
Needle 8 is cleaned.The pipeline support 5 for being used to support pipeline is equipped in shell 19.Specimen needle 7 and reagent needle 8 are sampling this and examination
Agent and discharge sample and reagent are cleaned after completing, and are prepared for next operation.
In this example, the reagent needle 8 is equipped with pre-heating module to preheat to the reagent needle 8.It is pre- for needing
The reagent of heating can heat up to reagent needle 8 by the pre-heating module of reagent needle 8, and candidate agent is drawn into reagent needle 8
It can be heated up by the reagent needle 8 of preheating to reagent, without being additionally individually incubated for (heating) to reagent, be mentioned later
High working efficiency.
The useless cup accommodating mechanism includes useless cup storage box 17, and the cup storage box 17 that gives up is arranged by storage box drawer 18 in shell
19 lower part of body is at the position of detection system 9.New reaction cup comes in that the reaction detected will be replaced in detection system 9
Cup, the reaction cup that new reaction cup will test release sense channel 906, and the reaction cup detected will directly fall into useless cup and receive
Case 17, then taken out from shell 19 by storage box drawer 18.
Automatic coagulation analyzer according to the present invention further comprise wireless communication module with communicated with other equipment from
And carry out testing result output.
According to an embodiment of the invention, 19 top of shell is equipped with the cover that can open the inner space of shell 19
Lid.
Automatic coagulation analyzer according to the present invention when being detected, is set by the touch display screen 2 of human-computer interaction
Detection project is set, empty reaction cup 104 enters reaction cup feed system 1 from into rim of a cup, and reaction cup 104 is from delivery chute 103 by anti-
Glass catch bar 109 is answered to be pushed to storage cup slot 114, storage cup slot 114 is slided on storage cup bottom plate 112 close to the position of detection system 9
It sets, the reaction cup in storage cup slot 114 is pushed to sense channel 906 via slideway 905 by push rod 116, thus empty reaction cup quilt
Reaction cup feed system 1 is delivered to detection system 9, and reaction cup enters after the sense channel 906 of detection system 9 through sample and examination
Sample to be detected and required reagent is added in agent transportation system, and after detection, the reaction cup newly entered, which will test, to be finished
Reaction cup head into useless cup storage box 17.Testing result module can be sent to other equipment by wireless communication to be printed
Output.
The description that the specific illustrative embodiment of the present invention is presented in front is for the purpose of illustration and description.Front
Description be not intended to become without missing, be not intended to limit the invention to disclosed precise forms, it is clear that root
It is possible for much changing and change all according to above-mentioned introduction.The exemplary embodiment was chosen and described for the sake of explain this hair
Bright certain principles and practical application, so that others skilled in the art can be realized and utilize of the invention each
Kind illustrative embodiments and its various selection forms and modification.The scope of the present invention be intended to by the appended claims and
Its equivalents is limited.
Claims (19)
1. a kind of automatic coagulation analyzer, which is characterized in that including shell, reaction cup feeding system is provided in the shell
System, sample and reagent delivery system, detection system, sample bit, reagent position, useless cup accommodating mechanism, for scanned samples information
The host system of scanning system and the work for controlling the automatic coagulation analyzer；The reaction cup feed system passes through
The shell receives reaction cup into rim of a cup from outside, so that reaction cup is delivered to the detection system；The sample and examination
Agent transportation system is arranged to sample and reagent being delivered to the detection system from the sample bit and the reagent position；It is described useless
Cup accommodating mechanism is arranged to the reaction cup that storage detection finishes from the detection system；The host system includes human-computer interaction
Module and control module.
2. automatic coagulation analyzer according to claim 1, which is characterized in that the reaction cup feed system, described
Detection system, the sample bit and the reagent position are arranged at the lower part of the shell, the reaction cup feed system setting
In the side of the detection system, the institute opposite with the reaction cup feed system is arranged in the sample bit and the reagent position
The other side of detection system is stated, the sample and reagent delivery system are arranged in the top of the shell and can be in the inspections
It is moved between examining system and the sample bit and the reagent position.
3. automatic coagulation analyzer according to claim 1 or 2, which is characterized in that the reaction cup feed system packet
Include delivery chute, link slot, the storage cup slot being arranged on storage cup bottom plate, reaction cup pushing mechanism and push rod；The link slot setting
Between the delivery chute and the storage cup bottom plate；The first end of the delivery chute is reached by the shell into rim of a cup
To receive reaction cup, the second end of the delivery chute is vertically connected with the link slot, described defeated for the outside of the shell
It send and is equipped with conveyer belt in slot so that reaction cup is delivered to the second end from the first end；The storage cup slot slidably connects
It connects to be parallel to the link slot sliding on the storage cup bottom plate on storage cup bottom plate, when the storage cup slot slides into the storage
When the position of the close link slot of bottom of a cup plate, the storage cup slot is connected with the link slot；The reaction cup pushing mechanism
The reaction cup at the second end will be located at the delivery chute is set via the company close to the second end of the delivery chute
Access slot is pushed in the storage cup slot；The reaction cup that the push rod is arranged to be placed in the storage cup slot close to the storage cup slot
It is pushed in the detection system.
4. automatic coagulation analyzer according to claim 3, which is characterized in that the conveyer belt in the delivery chute passes through
First stepping motor driven, the reaction cup pushing mechanism include supporting plate, the transmission belt being arranged on the supporting plate and by
The reaction cup catch bar of transmission belt driving, the transmission belt is by second stepper motor driving, and the transmission belt is from described
It is extended to above the second end of delivery chute above the position of the storage cup bottom plate being connected with the link slot, the reaction cup
Catch bar is by connection frame with the transmission band connection to be pushed away reaction cup from the delivery chute by the reaction cup catch bar
It moves in the storage cup slot.
5. automatic coagulation analyzer according to claim 4, which is characterized in that set at the second end of the delivery chute
Reaction cup inductor is equipped with to incude whether reaction cup reaches at the second end of the delivery chute；Setting at the top of the supporting plate
There are two position sensors to be respectively induced whether reaction cup catch bar reaches initial position and result position, the initial position
Position when starting driving a reaction cup for reaction cup catch bar where the reaction cup catch bar, the result position are reaction cup
Position of catch bar when reaction cup is pushed in the storage cup slot where the reaction cup catch bar.
6. automatic coagulation analyzer according to claim 3, which is characterized in that the storage cup bottom plate is equipped with sliding rail,
The storage cup trench bottom is equipped with the sliding slot cooperated with the sliding rail, and the storage cup slot passes through third stepping motor driven, the storage
Cup slot is connected to slide on the storage cup bottom plate with the motor driving plate of the third stepper motor.
7. automatic coagulation analyzer according to claim 6, which is characterized in that for by the reaction in the storage cup slot
The push rod that cup is pushed in detection system is slidably connected by connection movable block with the motor driving plate, the push rod
It connects and can be moved relative to the connection movable block with the connection movable block, the push rod with the connection by moving
The spindle motor of motion block connection drives, the storage cup slot, the connection movable block, the push rod and spindle motor entirety
Ground is driven by the motor driving plate of the third stepper motor integrally to move along the storage cup bottom plate.
8. automatic coagulation analyzer according to claim 1 or 2, which is characterized in that the detection system includes detection
Bracket, the heating bottom plate being connected at the top of the detection support and the sense channel being connected on the heating bottom plate, the inspection
Channel is surveyed to be connected with the reaction cup feed system by slideway so that reaction cup enters institute from the reaction cup feed system
Sense channel is stated, the first side of the sense channel is provided with luminous circuit board to utilize sample and the examination in photo-irradiation reaction cup
Agent, second side opposite with first side of the sense channel be provided with detection circuit board in reaction cup sample and
Reagent carries out light data acquisition, and the heating bottom plate is equipped with overheat switch so that the temperature control of the heating bottom plate to exist
In preset range.
9. automatic coagulation analyzer according to claim 8, which is characterized in that the first side of the sense channel and
Two sides are respectively arranged with luminous circuit board lid and detection circuit board lid.
10. automatic coagulation analyzer according to claim 8, which is characterized in that the channel slot of the sense channel
Inner sidewall is equipped with stationary spring to fix the reaction cup in channel slot.
11. automatic coagulation analyzer according to claim 8, which is characterized in that the luminous circuit board is fixed on institute
It states on the lateral wall of the first side of sense channel, the side wall of the first side of the sense channel is equipped with loophole.
12. automatic coagulation analyzer according to claim 8, which is characterized in that the bottom of the heating bottom plate and inspection
It surveys the corresponding position in channel and is equipped with heating sheet.
13. automatic coagulation analyzer according to claim 8, which is characterized in that the detection circuit board is arranged in institute
On the lateral wall for stating second side of sense channel.
14. automatic coagulation analyzer according to claim 1 or 2, which is characterized in that the sample and reagent delivery system
System includes first movement arm, the second moving arm, specimen needle and reagent needle, and second moving arm is slidably connected described first
Can be moved between the sample bit and the reagent position relative to the first movement arm on moving arm, the specimen needle
It is connected to the side close to the sample bit of second moving arm, the reagent needle is connected to leaning on for second moving arm
The side of the nearly reagent position, the specimen needle and the reagent needle can be moved up and down relative to second moving arm,
The first movement arm is slidably connected on the posterior medial wall of the shell by sliding panel so that the first movement arm
Transverse direction along the posterior medial wall moves, to drive the specimen needle and the reagent needle in the sample bit and institute
It states and is moved between reagent position and the detection system.
15. automatic coagulation analyzer according to claim 14, which is characterized in that further comprise described for cleaning
The cleaning liquid pipeline of the cleaning position of specimen needle and the reagent needle, hull outside enters shell by the pipe interface on the shell
Body with the specimen needle and the reagent needle to connect, to carry out in the cleaning position to the specimen needle and the reagent needle
Cleaning.
16. automatic coagulation analyzer according to claim 14, which is characterized in that the reagent needle is equipped with pre-add hot-die
Block is to preheat the reagent needle.
17. automatic coagulation analyzer according to claim 1 or 2, which is characterized in that the useless cup accommodating mechanism includes
The lower part of the housing is arranged in close to the position of the detection system by storage box drawer in useless cup storage box, the useless cup storage box
Set place.
18. automatic coagulation analyzer according to claim 1 or 2, which is characterized in that further comprise radio communication mold
Block with other equipment to communicate to carry out testing result output.
19. automatic coagulation analyzer according to claim 1 or 2, which is characterized in that the upper part of the housing is equipped with can
Open the cover of the inner space of the shell.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811344152.8A CN109283351B (en) | 2018-11-13 | 2018-11-13 | Full-automatic blood coagulation analyzer |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811344152.8A CN109283351B (en) | 2018-11-13 | 2018-11-13 | Full-automatic blood coagulation analyzer |
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| CN109283351B CN109283351B (en) | 2022-03-22 |
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| CN201811344152.8A Active CN109283351B (en) | 2018-11-13 | 2018-11-13 | Full-automatic blood coagulation analyzer |
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Cited By (3)
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| CN112014582A (en) * | 2020-08-31 | 2020-12-01 | 成都艾科斯伦医疗科技有限公司 | Scheduling method of full-automatic coagulation analyzer |
| CN113567688A (en) * | 2021-07-07 | 2021-10-29 | 北京九强生物技术股份有限公司 | Blood coagulation analyzer |
| CN112014582B (en) * | 2020-08-31 | 2024-05-03 | 成都艾科斯伦医疗科技有限公司 | Scheduling method of full-automatic coagulation analyzer |
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| CN109283351B (en) | 2022-03-22 |
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