CN109259238A - A kind of preparation method of seal oil auxiliary blood fat reducing soft capsule - Google Patents
A kind of preparation method of seal oil auxiliary blood fat reducing soft capsule Download PDFInfo
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- CN109259238A CN109259238A CN201811370901.4A CN201811370901A CN109259238A CN 109259238 A CN109259238 A CN 109259238A CN 201811370901 A CN201811370901 A CN 201811370901A CN 109259238 A CN109259238 A CN 109259238A
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- soft capsule
- seal oil
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- blood fat
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- 239000007901 soft capsule Substances 0.000 title claims abstract description 50
- 239000008280 blood Substances 0.000 title claims abstract description 36
- 210000004369 blood Anatomy 0.000 title claims abstract description 36
- 238000002360 preparation method Methods 0.000 title claims abstract description 27
- 239000003921 oil Substances 0.000 claims abstract description 35
- 235000019198 oils Nutrition 0.000 claims abstract description 35
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 18
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 claims abstract description 11
- 229940083466 soybean lecithin Drugs 0.000 claims abstract description 11
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 9
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 9
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 9
- 239000011709 vitamin E Substances 0.000 claims abstract description 9
- 229940046009 vitamin E Drugs 0.000 claims abstract description 9
- 238000000034 method Methods 0.000 claims abstract description 8
- 238000004806 packaging method and process Methods 0.000 claims abstract description 6
- 230000008569 process Effects 0.000 claims abstract description 6
- 238000004513 sizing Methods 0.000 claims abstract description 6
- 239000001335 perilla frutescens leaf extract Substances 0.000 claims abstract description 5
- 239000003292 glue Substances 0.000 claims description 38
- 235000019197 fats Nutrition 0.000 claims description 22
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 21
- 238000003756 stirring Methods 0.000 claims description 17
- 108010010803 Gelatin Proteins 0.000 claims description 12
- 229920000159 gelatin Polymers 0.000 claims description 12
- 239000008273 gelatin Substances 0.000 claims description 12
- 235000019322 gelatine Nutrition 0.000 claims description 12
- 235000011852 gelatine desserts Nutrition 0.000 claims description 12
- 239000008213 purified water Substances 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 238000013019 agitation Methods 0.000 claims description 5
- 238000009835 boiling Methods 0.000 claims description 5
- 239000002775 capsule Substances 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 4
- 239000000470 constituent Substances 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 4
- PIFPCDRPHCQLSJ-WYIJOVFWSA-N 4,8,12,15,19-Docosapentaenoic acid Chemical compound CC\C=C\CC\C=C\C\C=C\CC\C=C\CC\C=C\CCC(O)=O PIFPCDRPHCQLSJ-WYIJOVFWSA-N 0.000 claims description 2
- PIFPCDRPHCQLSJ-UHFFFAOYSA-N Clupanodonic acid Natural products CCC=CCCC=CCC=CCCC=CCCC=CCCC(O)=O PIFPCDRPHCQLSJ-UHFFFAOYSA-N 0.000 claims description 2
- 235000021290 n-3 DPA Nutrition 0.000 claims description 2
- DVSZKTAMJJTWFG-SKCDLICFSA-N (2e,4e,6e,8e,10e,12e)-docosa-2,4,6,8,10,12-hexaenoic acid Chemical compound CCCCCCCCC\C=C\C=C\C=C\C=C\C=C\C=C\C(O)=O DVSZKTAMJJTWFG-SKCDLICFSA-N 0.000 claims 1
- GZJLLYHBALOKEX-UHFFFAOYSA-N 6-Ketone, O18-Me-Ussuriedine Natural products CC=CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O GZJLLYHBALOKEX-UHFFFAOYSA-N 0.000 claims 1
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims 1
- KAUVQQXNCKESLC-UHFFFAOYSA-N docosahexaenoic acid (DHA) Natural products COC(=O)C(C)NOCC1=CC=CC=C1 KAUVQQXNCKESLC-UHFFFAOYSA-N 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 6
- 239000002994 raw material Substances 0.000 abstract description 5
- 235000013402 health food Nutrition 0.000 abstract description 3
- 230000010534 mechanism of action Effects 0.000 abstract description 3
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 201000010099 disease Diseases 0.000 description 4
- 235000015112 vegetable and seed oil Nutrition 0.000 description 4
- 235000012000 cholesterol Nutrition 0.000 description 3
- 235000021323 fish oil Nutrition 0.000 description 3
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 208000024172 Cardiovascular disease Diseases 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 2
- 201000005577 familial hyperlipidemia Diseases 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 description 2
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 208000032928 Dyslipidaemia Diseases 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 208000017170 Lipid metabolism disease Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 235000004347 Perilla Nutrition 0.000 description 1
- 241000229722 Perilla <angiosperm> Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 206010008118 cerebral infarction Diseases 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 239000010685 fatty oil Substances 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002000 scavenging effect Effects 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a kind of preparation methods of seal oil auxiliary blood fat reducing soft capsule.Seal oil auxiliary blood fat reducing soft capsule of the invention is using seal oil, Purple Perilla Seed Oil, soybean lecithin, vitamin E as raw material, and through mixing, pelleting, sizing is dry, the processes such as ball, packaging is selected to be made.The effect of four kinds of raw materials play auxiliary reducing blood lipid by different mechanism of action, product function and effect can be improved in compatible use.Stablize through seal oil prepared by the present invention auxiliary blood fat reducing soft capsule product, it is the ideal health food of Hyperlipidemia crowd that reliable in quality, which can safely and effectively be eaten for a long time,.
Description
Technical field
The present invention relates to a kind of preparations of seal oil auxiliary blood fat reducing soft capsule, belong to field of health care food.
Background technique
Cardiovascular disease is a kind of high incidence, high mortality, the disease of high disability rate, does great harm to human body, causes
There are many factor of the disease, including inherent cause, hypertension, hyperlipidemia, diabetes, smoking bad life habits etc., wherein blood
Rouge is one of most important risk factor extremely, and the long-term blood lipid that controls can be formed in suitable level with prevention of arterial atherosis
And its development, efficiently control or prevent the incidence and the death rate of cardiovascular disease.New investigation shows, China 18 years old or more blood
Rouge exception crowd has reached 1.6 hundred million, in 35 years old or more crowd, has 25,000,000 people while suffering from hypertension and hyperlipemia
Disease, dyslipidemia rise to original 3~5 times to the danger of China resident.
China's health-care food for assisting blood fat lowering is often broadly divided into animal tallow oil and Chinese medical extract with raw material at present, and moves
Object fat oil is mainly using fish oil as representative.Most of fish oil health food through inquiring China's approval is raw with single raw material fish oil
Preparation is produced, although can reach auxiliary reducing blood lipid, mechanism of action is single, and function and effect are not significant enough.Therefore, it is badly in need of out
The fatty oils health food for sending out novel built auxiliary reducing blood lipid, can be improved product efficacy, improve the market competitiveness.
Summary of the invention
It is an object of the invention to solve the deficiencies in the prior art, provide can long-term safety it is edible and with health role
A kind of seal oil auxiliary blood fat reducing soft capsule preparation method.
In order to achieve the above-mentioned object of the invention, the invention provides the following technical scheme:
A kind of preparation method of seal oil auxiliary blood fat reducing soft capsule, feature the following steps are included:
(1) preparation of content: Purple Perilla Seed Oil being added in Agitation Tank and is heated up to 60~70 DEG C while stirring, is added after reaching temperature
Enter soybean lecithin stirring and dissolving, add seal oil, vitamin E uniform stirring 30 minutes, obtains soft capsule content, it is spare；
(2) prepared by glue: will be stirred and heated to 70~80 DEG C in glycerol, purified water investmentization glue tank, then puts into gelatin stirring
Uniformly, boiling is entirely molten to gelatin；Vacuum pump is opened, vacuum degree >=-0.07Mpa is closed vacuum after being evacuated to glue bubble-free, opened
Exhaust valve；By the double-deck 100 mesh sock filtrations of the glue after deflation, obtained glue, which is placed in glue-storing barrel, to be stood, glue temperature
60 ± 5 DEG C of holding, it is spare；
(3) preparation of soft capsule: soft capsule content, glue are pressed into soft capsule in encapsulating machine, the soft capsule pressed is set
It is formed in rotating cage drying, then is selected the processes such as ball, packaging that seal oil auxiliary blood fat reducing soft capsule finished product is made.
Preferably, content constituent includes: 40~50 parts of seal oil, purple perilla by weight in the step (1)
25~30 parts of seed oil, 20~25 parts of soybean lecithin, 5~10 parts of vitamin E.
Preferably, seal oil quality requirement clupanodonic acid (EPA) content >=5.5%, 20 in the step (1)
Two carbon acid (DHA) content >=6.0%.
Preferably, soybean lecithin quality requirement acetone insoluble matter content >=65% in the step (1).
Preferably, gelatin in glue constituent in the step (2), glycerol, purified water proportion be 1:0.4~0.6:
1。
Preferably, soft capsule pelleting capsule skin thickness is 0.70~0.78mm in the step (3), and grain weight is 1000mg/.
Preferably, sizing drying condition in the step (3) are as follows: 20~25 DEG C of temperature, relative humidity 25~35%, time
20~24 hours.
Preferably, the seal oil auxiliary blood fat reducing soft capsule eating method and amount are mouth 3 times a day, 2 tablets each time
Clothes.
Compared with prior art, the invention has the advantages that, the seal oil that the present invention uses can effectively adjust blood
Rouge reduces cholesterol, inhibits platelet aggregation, the heart and brain blood such as atherosclerosis, coronary heart disease, myocardial infarction, cerebral infarction
The formation of pipe disease；The soybean lecithin obtained by Hydrolysis kinetics in crude soya bean, active material phosphatidyl choline (PC) is added
The mesh of reduction blood lipid can be reached by increasing the operating to triglycerides TG and emulsification, the scavenging effect to total cholesterol TC
's；The intracorporal most of cholesterol of liver catabolism can be promoted by being added in Purple Perilla Seed Oil, so that it is hard to reduce hyperlipemia, artery
Change the generation of disease and heart disease etc.；Vitamin E, which is added, not only keeps product to stablize, and also enhances the effect of product reducing blood lipid.
The effect of four kinds of raw materials play auxiliary reducing blood lipid by different mechanism of action, product function and effect can be improved in compatible use, together
When also ensure that product is stablized, reliable in quality can safely and effectively be eaten for a long time.
Specific embodiment
[embodiment 1]
A kind of preparation method of seal oil auxiliary blood fat reducing soft capsule the following steps are included:
(1) preparation of content: 25 parts of Purple Perilla Seed Oils are added in Agitation Tank and are heated up to 60~70 DEG C while stirring, reach temperature
Afterwards be added 20 parts of soybean lecithin stirring and dissolvings, add 50 parts of seal oils, 5 parts vitamin E uniform stirring 30 minutes, obtain soft capsule
Content, it is spare；
(2) prepared by glue: by glycerol, purified water by being stirred and heated to 70~80 DEG C in the proportion investmentization glue tank of 0.4:1, then
It puts into and is stirred evenly with the gelatin of purified water equivalent, boiling is entirely molten to gelatin；Vacuum pump is opened, vacuum degree >=-0.07Mpa is taken out
Vacuum is closed after vacuum to glue bubble-free, begin to rehearse air valve；By the glue after deflation with the double-deck 100 mesh sock filtrations, obtained glue
Liquid is placed in glue-storing barrel and stands, 60 ± 5 DEG C of glue temperature holding, spare；
(3) preparation of soft capsule: soft capsule content, glue are pressed into soft capsule in encapsulating machine, control capsule skin thickness
0.70~0.78mm, grain weight 1000mg/, the soft capsule pressed is placed in rotating cage in 25 DEG C of temperature, the condition of relative humidity 25%
Lower sizing is 20 hours dry, then is selected the processes such as ball, packaging that seal oil auxiliary blood fat reducing soft capsule finished product is made.
[embodiment 2]
A kind of preparation method of seal oil auxiliary blood fat reducing soft capsule the following steps are included:
(1) preparation of content: 30 parts of Purple Perilla Seed Oils are added in Agitation Tank and are heated up to 60~70 DEG C while stirring, reach temperature
Afterwards be added 20 parts of soybean lecithin stirring and dissolvings, add 40 parts of seal oils, 10 parts vitamin E uniform stirring 30 minutes, obtain flexible glue
It is intracapsular tolerant, it is spare；
(2) prepared by glue: by glycerol, purified water by being stirred and heated to 70~80 DEG C in the proportion investmentization glue tank of 0.5:1, then
It puts into and is stirred evenly with the gelatin of purified water equivalent, boiling is entirely molten to gelatin；Vacuum pump is opened, vacuum degree >=-0.07Mpa is taken out
Vacuum is closed after vacuum to glue bubble-free, begin to rehearse air valve；By the glue after deflation with the double-deck 100 mesh sock filtrations, obtained glue
Liquid is placed in glue-storing barrel and stands, 60 ± 5 DEG C of glue temperature holding, spare；
(3) preparation of soft capsule: soft capsule content, glue are pressed into soft capsule in encapsulating machine, control capsule skin thickness
0.70~0.78mm, grain weight 1000mg/, the soft capsule pressed is placed in rotating cage in 20 DEG C of temperature, the condition of relative humidity 25%
Lower sizing is 22 hours dry, then is selected the processes such as ball, packaging that seal oil auxiliary blood fat reducing soft capsule finished product is made.
[embodiment 3]
A kind of preparation method of seal oil auxiliary blood fat reducing soft capsule the following steps are included:
(1) preparation of content: 30 parts of Purple Perilla Seed Oils are added in Agitation Tank and are heated up to 60~70 DEG C while stirring, reach temperature
Afterwards be added 25 parts of soybean lecithin stirring and dissolvings, add 40 parts of seal oils, 5 parts vitamin E uniform stirring 30 minutes, obtain soft capsule
Content, it is spare；
(2) prepared by glue: by glycerol, purified water by being stirred and heated to 70~80 DEG C in the proportion investmentization glue tank of 0.6:1, then
It puts into and is stirred evenly with the gelatin of purified water equivalent, boiling is entirely molten to gelatin；Vacuum pump is opened, vacuum degree >=-0.07Mpa is taken out
Vacuum is closed after vacuum to glue bubble-free, begin to rehearse air valve；By the glue after deflation with the double-deck 100 mesh sock filtrations, obtained glue
Liquid is placed in glue-storing barrel and stands, 60 ± 5 DEG C of glue temperature holding, spare；
(3) preparation of soft capsule: soft capsule content, glue are pressed into soft capsule in encapsulating machine, control capsule skin thickness
0.70~0.78mm, grain weight 1000mg/, the soft capsule pressed is placed in rotating cage in 20 DEG C of temperature, the condition of relative humidity 35%
Lower sizing is 20 hours dry, then is selected the processes such as ball, packaging that seal oil auxiliary blood fat reducing soft capsule finished product is made.
For the ordinary skill in the art, specific embodiment is only exemplarily described the present invention,
Obviously the present invention specific implementation is not subject to the restrictions described above, as long as use the inventive concept and technical scheme of the present invention into
The improvement of capable various unsubstantialities, or not improved the conception and technical scheme of the invention are directly applied to other occasions
, it is within the scope of the present invention.
Claims (7)
1. a kind of preparation method of seal oil auxiliary blood fat reducing soft capsule, feature the following steps are included:
(1) preparation of content: Purple Perilla Seed Oil being added in Agitation Tank and is heated up to 60~70 DEG C while stirring, is added after reaching temperature
Enter soybean lecithin stirring and dissolving, add seal oil, vitamin E uniform stirring 30 minutes, obtains soft capsule content, it is spare；
(2) prepared by glue: will be stirred and heated to 70~80 DEG C in glycerol, purified water investmentization glue tank, then puts into gelatin stirring
Uniformly, boiling is entirely molten to gelatin；Vacuum pump is opened, vacuum degree >=-0.07Mpa is closed vacuum after being evacuated to glue bubble-free, opened
Exhaust valve；By the double-deck 100 mesh sock filtrations of the glue after deflation, obtained glue, which is placed in glue-storing barrel, to be stood, glue temperature
60 ± 5 DEG C of holding, it is spare；
(3) preparation of soft capsule: soft capsule content, glue are pressed into soft capsule in encapsulating machine, the soft capsule pressed is set
It is formed in rotating cage drying, then is selected the processes such as ball, packaging that seal oil auxiliary blood fat reducing soft capsule finished product is made.
2. a kind of preparation method of seal oil auxiliary blood fat reducing soft capsule as described in claim 1, which is characterized in that the step
(1) content constituent includes: 40~50 parts of seal oil, 25~30 parts of Purple Perilla Seed Oil, soybean lecithin 20 by weight in
~25 parts, 5~10 parts of vitamin E.
3. a kind of preparation method of seal oil auxiliary blood fat reducing soft capsule as described in claim 1, which is characterized in that the step
(1) seal oil quality requirement clupanodonic acid (EPA) content >=5.5%, docosahexaenoic acid (DHA) content in >=
6.0%。
4. a kind of preparation method of seal oil auxiliary blood fat reducing soft capsule as described in claim 1, which is characterized in that the step
(1) soybean lecithin quality requirement acetone insoluble matter content >=65% in.
5. a kind of preparation method of seal oil auxiliary blood fat reducing soft capsule as described in claim 1, which is characterized in that the step
(2) gelatin in glue constituent in, glycerol, purified water proportion be 1:0.4~0.6:1.
6. a kind of preparation method of seal oil auxiliary blood fat reducing soft capsule as described in claim 1, which is characterized in that the step
(3) soft capsule pelleting capsule skin thickness is 0.70~0.78mm in, and grain weight is 1000mg/.
7. a kind of preparation method of seal oil auxiliary blood fat reducing soft capsule as described in claim 1, which is characterized in that the step
(3) sizing drying condition in are as follows: 20~25 DEG C of temperature, relative humidity 25~35%, the time 20~24 hours.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811370901.4A CN109259238A (en) | 2018-11-18 | 2018-11-18 | A kind of preparation method of seal oil auxiliary blood fat reducing soft capsule |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811370901.4A CN109259238A (en) | 2018-11-18 | 2018-11-18 | A kind of preparation method of seal oil auxiliary blood fat reducing soft capsule |
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| CN109259238A true CN109259238A (en) | 2019-01-25 |
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|---|---|---|---|---|
| CN102423338A (en) * | 2011-12-13 | 2012-04-25 | 九三粮油工业集团有限公司 | Compound purple perilla seed oil soft capsule for reducing blood lipid |
| CN103800435A (en) * | 2014-02-12 | 2014-05-21 | 山东天地健生物工程有限公司 | Seal oil soft capsule |
| CN105285978A (en) * | 2015-09-23 | 2016-02-03 | 威海紫光金奥力生物技术有限公司 | Auxiliarily blood lipid lowering seal oil and purple perilla seed oil soft capsule |
| CN106880046A (en) * | 2017-02-10 | 2017-06-23 | 合肥师范学院 | A kind of Blueberry pigment soft capsule and preparation method thereof |
-
2018
- 2018-11-18 CN CN201811370901.4A patent/CN109259238A/en not_active Withdrawn
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102423338A (en) * | 2011-12-13 | 2012-04-25 | 九三粮油工业集团有限公司 | Compound purple perilla seed oil soft capsule for reducing blood lipid |
| CN103800435A (en) * | 2014-02-12 | 2014-05-21 | 山东天地健生物工程有限公司 | Seal oil soft capsule |
| CN105285978A (en) * | 2015-09-23 | 2016-02-03 | 威海紫光金奥力生物技术有限公司 | Auxiliarily blood lipid lowering seal oil and purple perilla seed oil soft capsule |
| CN106880046A (en) * | 2017-02-10 | 2017-06-23 | 合肥师范学院 | A kind of Blueberry pigment soft capsule and preparation method thereof |
Non-Patent Citations (4)
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