CN109258686A - Disease-resistant composition pesticide and its preparation method and application - Google Patents
Disease-resistant composition pesticide and its preparation method and application Download PDFInfo
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- CN109258686A CN109258686A CN201811201464.3A CN201811201464A CN109258686A CN 109258686 A CN109258686 A CN 109258686A CN 201811201464 A CN201811201464 A CN 201811201464A CN 109258686 A CN109258686 A CN 109258686A
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- Prior art keywords
- copper
- fluxapyroxad
- agent
- disease
- hydroxyquinolinate
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/16—Heavy metals; Compounds thereof
- A01N59/20—Copper
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01G—HORTICULTURE; CULTIVATION OF VEGETABLES, FLOWERS, RICE, FRUIT, VINES, HOPS OR SEAWEED; FORESTRY; WATERING
- A01G13/00—Protecting plants
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01G—HORTICULTURE; CULTIVATION OF VEGETABLES, FLOWERS, RICE, FRUIT, VINES, HOPS OR SEAWEED; FORESTRY; WATERING
- A01G22/00—Cultivation of specific crops or plants not otherwise provided for
- A01G22/20—Cereals
- A01G22/22—Rice
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
Abstract
The invention discloses a kind of disease-resistant composition pesticides and its preparation method and application.The present invention discloses a kind of disease-resistant composition pesticide first, is made of fluxapyroxad and copper 8-hydroxyquinolinate.The present invention further discloses a kind of pesticidal preparations, including prevent and treat upper a effective amount of fluxapyroxad and copper 8-hydroxyquinolinate and insecticides adjuvant or excipients.The present invention reduces times for spraying, reduces drug cost by producing fluxapyroxad and copper 8-hydroxyquinolinate two kinds of active components compounding significant synergistic function, improving the control efficiency to rice sheath blight disease and extend the medicament lasting period.The disease-resistant composition pesticide of the present invention can prevent Rhizoctonia solani Kuhn from developing drug resistance, and extend the service life of pesticide and good to crop safety.
Description
Technical field
The present invention relates to the disease-resistant pesticide groups of a kind of composition pesticide more particularly to a kind of Fluxapyroxad-containsterilization and copper 8-hydroxyquinolinate
Object is closed, the invention further relates to the preparation method of the disease-resistant composition pesticide and its applications in controlling plant diseases, belong to
Disease-resistant composition pesticide field.
Background technique
Fluxapyroxad (fluxapyroxad) is BASF AG in the SDHI class fungicide of listing in 2012, this kind of to kill
The mechanism of action of microbial inoculum mainly inhibits pathogen succinate dehydrogenase activity, influences the electron transmission system of pathogen respiratory chain
System, hinders the metabolism of its energy, inhibits the growth of pathogen, leads to its death, to achieve the purpose that controlling disease；It has
Efficiently, wide spectrum, holding effect, excellent uptake and translocation effect, strong drug action, persistent, obvious effect of increasing production, safety are good, and
It is efficient to triazole type and methoxy acrylic generation resistant strain, wide market.Currently, mainly being used in actual production
In cereal, soybean, corn, rape, fruit tree, vegetables, beet, peanut, cotton, lawn etc., prevent and treat by Septoria musiva, Botrytis cinerea
Disease caused by the disease fungus such as bacterium, powdery mildew, tail spore bacterium, handle rest fungus, rhizoctonia, nuclear cavity bacteria.
Copper 8-hydroxyquinolinate be a kind of wide spectrum, efficiently, the Chelating state organic copper fungicide of low toxicity, be used for wood preservation, cotton, leather
Sterilization, to crop fungi, bacterial disease all have it is excellent prevent, treat effect, have both organic quinolines and copper agent
Double sterilization effect, target site is more, and germ is used for multiple times and is not easy to produce resistance, efficient to conventional sterilization agent resistant strain；And
The medicament lasting period is long, is 15 days.At present production in, copper 8-hydroxyquinolinate be mainly used in prevention and treatment tomato late blight, it is bacillary burst
Ulcer, capsicum epidemic disease, canker, shot hole, downy mildew, cucumber downy mildew, bacterial leaf spot, the peronospora tabacina of lichee, watermelon
The bacteriums such as downy mildew, anthracnose, Acidovorax Avenae Subsp. Citrulli, the late blight of potato or fungal disease.
The difficulty of prevention and cure of phytopathogen is increasing at present, on the one hand, with the change of pattern of farming, melon fruits and vegetables etc.
Industrial crops cultivated area gradually expands, and disease occurrence degree, generation quantity increase, and increases preventing and treating upper difficulty；Separately
On the one hand, the resistance of pathogen selects to rise year by year under pressure in lasting medicament, and the control efficiency of single dose is had a greatly reduced quality, plant
Disease control is faced with significant challenge.It would therefore be highly desirable to need to develop a kind of compounded by Multiple Pesticides active constituent and for plant
Disease has the composition pesticide of significant collaboration prophylactic-therapeutic effect.
Summary of the invention
First technical problem to be solved by this invention is to provide a kind of disease-resistant composition pesticide, the disease-resistant pesticide combination
Using fluxapyroxad and copper 8-hydroxyquinolinate as main active, the two compounding has obvious synergistic function object, significantly improves
To the control efficiency of rice sheath blight disease, and extend the medicament lasting period；
Second technical problem to be solved by this invention is to provide a kind of preparation method of disease-resistant composition pesticide；
It includes rice that third technical problem to be solved by this invention, which is to provide the disease-resistant composition pesticide in prevention and treatment,
The application in plant disease including banded sclerotial blight.
In order to solve the above technical problems, the technical solution used in the present invention is:
The present invention discloses a kind of disease-resistant composition pesticide first, is made of fluxapyroxad and copper 8-hydroxyquinolinate.In mass ratio
Meter, fluxapyroxad: copper 8-hydroxyquinolinate=1-99:1-99；Preferably, fluxapyroxad: copper 8-hydroxyquinolinate=1-49:1-24.
It is further preferred that counting in mass ratio, fluxapyroxad: copper 8-hydroxyquinolinate=1:1.
The present invention has found that after fluxapyroxad and copper 8-hydroxyquinolinate mixture, activity and bactericidal effect are not by a large number of experiments
The active simple superposition of each component, but have significant synergistic effect.Fluxapyroxad, which compounds to match with copper 8-hydroxyquinolinate difference, compares water
The toxicity test of the sheath and culm blight of rice the result shows that, after fluxapyroxad is compounded with copper 8-hydroxyquinolinate according to mass ratio 1-99:1-99, each group is multiple
Ingredients, which still has rice sheath blight disease, prevents and kill off activity well, the EC respectively matched50Between 1.275-2.646, wherein matching 1:1
Active highest.Fluxapyroxad shows with respectively compounding for copper 8-hydroxyquinolinate with the synergy evaluation result for comparing rice sheath blight disease
After 1-99:1-99 is compounded in mass ratio, each group compounding agent shows synergy to rice sheath blight disease for fluxapyroxad and copper 8-hydroxyquinolinate
Activity is prevented and kill off, the EC respectively matched50Between 1.275-2.646, wherein the active highest of proportion 1:1；The co-toxicity coefficient respectively matched
Between 82.3-192.9, different ratio all has synergistic effect to rice sheath blight disease controlling, wherein fluxapyroxad: copper 8-hydroxyquinolinate
When proportion is 1:1, synergistic effect is most strong, and co-toxicity coefficient reaches 192.9.
The present invention also provides a kind of composition pesticides of controlling plant diseases, are activity by fluxapyroxad and copper 8-hydroxyquinolinate
Ingredient and auxiliary material pesticide-acceptable or carrier composition.
Auxiliary material or carrier pesticide-acceptable are added on the basis of composition pesticide of the present invention, according to the normal of pesticidal preparations
Rule method can be prepared into the various formulations of pesticide, for example: suspending agent, wettable powder, water dispersible granules, microemulsion, aqueous emulsion, oil
The preparation method of the dosage forms such as suspension, missible oil, these formulations of pesticide is well known to those skilled in the art.
Auxiliary material or carrier of the present invention, such as emulsifier, wetting dispersing agent, thickener, antifreezing agent, stabilizer, anti-corrosion
Agent, disintegrating agent, binder or filler etc. may each be component conventional in pesticide.For example, the emulsifier is selected from nonionic table
Face activating agent castor oil ethylene oxide adduct (EL40 or EL90), nonylphenol polyoxyethylene ether, fatty alcohol polyoxyethylene ether,
One or more of phenethyl phenol polyoxyethylene poly-oxygen propylene aether, APES formaldehyde condensation product.The wetting
Dispersing agent be selected from lauryl sodium sulfate, Nekal BX, alkylphenol-polyethenoxy base ether, naphthalene sulfonic acid-formaldehyde condensation product salt or poly-
The mixture that one or more of oxyethylene group polyoxypropylene ether block copolymers are formed according to arbitrary proportion.The increasing
Thick dose in xanthan gum, carboxymethyl cellulose, Sodium Polyacrylate, aluminum magnesium silicate, gaseous silicon oxide or attapulgite one
Kind is several.The antifreezing agent is in ethylene glycol, propylene glycol, glycerol, glycerol-ether diglycol or methyl propylene diglycol
It is any one or more than one according to arbitrary proportion form mixture.The stabilizer is selected from 2,6- di-t-butyl -4-
Any one or more in methylphenol (BHT), citric acid or butylated hydroxy anisole (BHA).The disintegrating agent is selected from urine
Any one or more in element, bentonite, montmorillonite or sodium alginate.The binder is selected from gelatin, Arabic gum, Huang
One of virgin rubber, sodium tripolyphosphate, phenolic resin or polyvinylpyrrolidone are a variety of.The filler can be kaolin
Deng.
As reference, the present invention provides the methods that the composition pesticide is prepared into agricultural chemicals suspension agent, comprising: by fluorine
Azoles bacterium amide, copper 8-hydroxyquinolinate and wetting agent, dispersing agent, antifreeze, preservative and part thickener (60-80% of total amount), part
Defoaming agent (60-80% of total amount) and water etc. are uniformly mixed, grinding, when partial size is at 5 μm, stop grinding, and remaining thickening is added
Agent and remaining defoaming agent obtain suspending agent product after adjusting uniformly.
As reference, the present invention provides the methods that the composition pesticide is prepared into microemulsion, comprising: by fluorine
Azoles bacterium amide and copper 8-hydroxyquinolinate dissolve in solvent and emulsifier becomes uniform oily phase, is slowly added into deionized water under stiring,
Formed WO emulsion, then it is agitated be allowed to rapid phase inversion into oil-in-water type, be cooled to room temperature and make up to balance, through filtering
Obtain microemulsion.
As reference, the present invention provides the methods that the composition pesticide is prepared into pesticide emulsion in water, comprising: by fluorine
Azoles bacterium amide and copper 8-hydroxyquinolinate are dissolved into homogeneous oil phase in solvent and emulsifier；By deionized water, antifreeze, preservative, defoaming
Agent is mixed into uniform water phase, and oily phase is added in water phase under high speed shear, obtains aqueous emulsion product.
As reference, the present invention provides the methods that the composition pesticide is prepared into pesticide water dispersible granules, comprising:
Fluxapyroxad, copper 8-hydroxyquinolinate and wetting agent, dispersing agent, filler etc. are subjected to co-grinding, after adding water kneading, pelletizer is added
In be granulated, then again through drying, screening obtain water dispersible granules product.
As reference, the present invention provides the methods that the composition pesticide is prepared into pesticide wettable, comprising:
Fluxapyroxad, copper 8-hydroxyquinolinate and various auxiliary agents and filler etc. are sufficiently mixed, after ultra-fine pulverizer disintegrating, is uniformly mixed and makes
Obtain wettable powder.
As reference, the present invention provides the methods that the composition pesticide is prepared into emulsifiable concentrates for agricultural chemicals agent, comprising: by fluorine
Azoles bacterium amide, copper 8-hydroxyquinolinate are dissolved in organic solvent, add emulsifier, under stiring mixed dissolution, it is transparent that individual event is made
Liquid is to get emulsifiable concentrate.
The application method and dosage of the suspending agent of composition pesticide of the present invention: it is diluted with water and makees even spraying；Dosage according to
Depending on pesticide effective component content in disease severity and the specific formulations of pesticide.
The present invention is using fluxapyroxad and copper 8-hydroxyquinolinate as the pesticide synergistic composition of main active, for including rice
Plant disease including banded sclerotial blight has extremely significant preventive effect.
Fluxapyroxad shows different ratio with Field information effect experiment of the oxine-copper composite preparation to rice sheath blight disease
Fluxapyroxad and the compound preparation of copper 8-hydroxyquinolinate have a favorable effect to rice sheath blight disease under experimental concentration, and better than
The prevention and treatment of 33.5% 1000 times of copper 8-hydroxyquinolinate suspending agent liquid, 42.4% azoles ether flutolanil 800 times of liquid of suspending agent to rice sheath blight disease
Effect；Wherein 40% 1000 times of liquid of fluxapyroxad copper 8-hydroxyquinolinate suspending agent (1:1) are best to rice sheath blight disease preventive effect, reach
98.04%.
In production, it is recommended to use 40% fluxapyroxad copper 8-hydroxyquinolinate suspending agent (1:1) 1000-2000 times of liquid is anti-to harness the river
The sheath and culm blight of rice carries out even spraying to rice using spray method, and continuous spraying is twice.Rain is met in 6 hours after application, waits and becomes a fine day
After should fill spray it is primary.
Technical solution of the present invention compared with prior art, has the advantages that
The present invention is by producing significant synergistic work for fluxapyroxad and copper 8-hydroxyquinolinate two kinds of active components compounding
With, improve the control efficiency to rice sheath blight disease, and extend the medicament lasting period, reduce times for spraying, reduce medication at
This.Mixed Pharmacy can prevent Rhizoctonia solani Kuhn from developing drug resistance, and extend the service life of pesticide species；Prevention and treatment is widened
Spectrum can prevent and treat mixing morbidity, can especially effectively prevent bacterium and fungi mixing disease；It is good to crop safety, meet pesticide
The security requirement of preparation.
Specific embodiment
The invention will now be further described with reference to specific embodiments, the advantages and features of the present invention will be with description and
It is apparent.It should be understood that described, examples are merely exemplary, does not constitute any restrictions to the scope of the present invention.This field
Technical staff should be understood that without departing from the spirit and scope of the invention can details to technical solution of the present invention and
Form is modified or is replaced, but these modifications or substitutions each fall within protection scope of the present invention.
1, raw medicine: 98% fluxapyroxad, 95% copper 8-hydroxyquinolinate.
1 50% fluxapyroxad copper 8-hydroxyquinolinate suspending agent (fluxapyroxad: copper 8-hydroxyquinolinate 99:1) of embodiment
Raw medicine, wetting agent, dispersing agent, freeze proof is weighed by above-mentioned recipe requirements (% is mass percent, similarly hereinafter)
Agent, preservative and part thickener (the 70% of total amount), part defoaming agent (the 70% of total amount) and water etc. are uniformly mixed, grinding,
When partial size is at 5 μm, stop grinding, obtains suspending agent product after remaining thickener and defoaming agent adjusting uniformly is added.
2 25% fluxapyroxad copper 8-hydroxyquinolinate suspending agent (fluxapyroxad: copper 8-hydroxyquinolinate 24:1) of embodiment
By above-mentioned recipe requirements weigh raw medicine, wetting agent, dispersing agent, antifreeze, preservative and part thickener (total amount
60%), part defoaming agent (the 60% of total amount) and water etc. are uniformly mixed, grinding, when partial size is at 5 μm, stop grinding, are added surplus
Remaining thickener and defoaming agent obtain suspending agent product after adjusting uniformly.
3 50% fluxapyroxad copper 8-hydroxyquinolinate suspending agent (fluxapyroxad: copper 8-hydroxyquinolinate 1:1) of embodiment
By above-mentioned recipe requirements weigh raw medicine, wetting agent, dispersing agent, antifreeze, preservative and part thickener (total amount
50%), part defoaming agent (the 50% of total amount) and water etc. are uniformly mixed, grinding, when partial size is at 5 μm, stop grinding, are added surplus
Remaining thickener and defoaming agent obtain suspending agent product after adjusting uniformly.
4 25% fluxapyroxad copper 8-hydroxyquinolinate suspending agent (fluxapyroxad: copper 8-hydroxyquinolinate 1:24) of embodiment
By above-mentioned recipe requirements weigh raw medicine, wetting agent, dispersing agent, antifreeze, preservative and part thickener (total amount
80%), part defoaming agent (the 80% of total amount) and water etc. are uniformly mixed, grinding, when partial size is at 5 μm, stop grinding, are added surplus
Remaining thickener and defoaming agent obtain suspending agent product after adjusting uniformly.
5 50% fluxapyroxad copper 8-hydroxyquinolinate suspending agent (fluxapyroxad: copper 8-hydroxyquinolinate 1:99) of embodiment
By above-mentioned recipe requirements weigh raw medicine, wetting agent, dispersing agent, antifreeze, preservative and part thickener (total amount
70%), part defoaming agent (the 70% of total amount) and water etc. are uniformly mixed, grinding, when partial size is at 5 μm, stop grinding, are added surplus
Remaining thickener and defoaming agent obtain suspending agent product after adjusting uniformly.
6 50% fluxapyroxad copper 8-hydroxyquinolinate wettable powder (fluxapyroxad: copper 8-hydroxyquinolinate 99:1) of embodiment
Raw medicine, various auxiliary agents and filler etc. are weighed by above-mentioned recipe requirements to be sufficiently mixed, and after ultra-fine pulverizer disintegrating, are mixed
It closes and uniformly obtains wettable powder product.
7 25% fluxapyroxad copper 8-hydroxyquinolinate wettable powder (fluxapyroxad: copper 8-hydroxyquinolinate 24:1) of embodiment
Raw medicine, various auxiliary agents and filler etc. are weighed by above-mentioned recipe requirements to be sufficiently mixed, and after ultra-fine pulverizer disintegrating, are mixed
It closes and uniformly obtains wettable powder product.
8 50% fluxapyroxad copper 8-hydroxyquinolinate wettable powder (fluxapyroxad: copper 8-hydroxyquinolinate 1:1) of embodiment
Raw medicine, various auxiliary agents and filler etc. are weighed by above-mentioned recipe requirements to be sufficiently mixed, and after ultra-fine pulverizer disintegrating, are mixed
It closes and uniformly obtains wettable powder product.
9 25% fluxapyroxad copper 8-hydroxyquinolinate wettable powder (fluxapyroxad: copper 8-hydroxyquinolinate 1:24) of embodiment
Raw medicine, various auxiliary agents and filler etc. are weighed by above-mentioned recipe requirements to be sufficiently mixed, and after ultra-fine pulverizer disintegrating, are mixed
It closes and uniformly obtains wettable powder product.
10 50% fluxapyroxad copper 8-hydroxyquinolinate wettable powder (fluxapyroxad: copper 8-hydroxyquinolinate 1:99) of embodiment
Raw medicine, various auxiliary agents and filler etc. are weighed by above-mentioned recipe requirements to be sufficiently mixed, and after ultra-fine pulverizer disintegrating, are mixed
It closes and uniformly obtains wettable powder product.
11 50% fluxapyroxad quinoline copper water dispersion granula (fluxapyroxad: copper 8-hydroxyquinolinate 99:1) of embodiment
By above-mentioned recipe requirements, raw medicine and wetting agent, dispersing agent, filler etc. are subjected to co-grinding, after adding water kneading,
It is added in pelletizer and is granulated, then obtain water dispersible granules product through drying, screening again.
12 25% fluxapyroxad quinoline copper water dispersion granula (fluxapyroxad: copper 8-hydroxyquinolinate 24:1) of embodiment
By above-mentioned recipe requirements, raw medicine and wetting agent, dispersing agent, filler etc. are subjected to co-grinding, after adding water kneading,
It is added in pelletizer and is granulated, then obtain water dispersible granules product through drying, screening again.
13 50% fluxapyroxad quinoline copper water dispersion granula (fluxapyroxad: copper 8-hydroxyquinolinate 1:1) of embodiment
By above-mentioned recipe requirements, raw medicine and wetting agent, dispersing agent, filler etc. are subjected to co-grinding, after adding water kneading,
It is added in pelletizer and is granulated, then obtain water dispersible granules product through drying, screening again.
14 25% fluxapyroxad quinoline copper water dispersion granula (fluxapyroxad: copper 8-hydroxyquinolinate 1:24) of embodiment
By above-mentioned recipe requirements, raw medicine and wetting agent, dispersing agent, filler etc. are subjected to co-grinding, after adding water kneading,
It is added in pelletizer and is granulated, then obtain water dispersible granules product through drying, screening again.
15 50% fluxapyroxad quinoline copper water dispersion granula (fluxapyroxad: copper 8-hydroxyquinolinate 1:99) of embodiment
By above-mentioned recipe requirements, raw medicine and wetting agent, dispersing agent, filler etc. are subjected to co-grinding, after adding water kneading,
It is added in pelletizer and is granulated, then obtain water dispersible granules product through drying, screening again.
The toxicity test of 1 rice sheath blight disease of test example is tested
1, reagent agent
98% fluxapyroxad raw medicine, 95% copper 8-hydroxyquinolinate raw medicine
2, for trying target
Rhizoctonia solani Kuhn (Rhzioctonia solani).
3, experimental condition
25 ± 1 DEG C of laboratory temperature.
4, test method
It operates as follows:
Using mycelial growth rate method, reagent agent is made into the mother liquor for being 10000mg/L containing effective component with sterile water,
The medical fluid that concentration is 1000,500,100,10, l, 0.1mg/L is configured to sterile water again.Draw 1mL medical fluid respectively with pipettor
It is uniformly mixed in the culture dish that diameter is 9cm with 9mL PDA culture medium (50 DEG C of culture medium temperature or so), ultimate density is made
For 100mg/L, 50mg/L, 10mg/L, 1mg/L, 0.1mg/L, 0.01mg/L band medicine plating medium, blank pair is made with sterile water
According to.
The Rhizoctonia solani Kuhn kept is activated, 25 DEG C of dark culturing 7d, in the sterilizing of cultured colony edge
Punch beats the mycelia block for taking diameter 5mm, is moved on on band medicine plating medium respectively, 3 repetitions are arranged in every processing.In 25 DEG C of perseverances
Warm incubator culture measures colony diameter using crossing method when compareing colony diameter length to culture dish diameter about 2/3,
Calculate colony diameter average value and mycelial growth inhibition rate.
Probability value are converted by 3 duplicate average bacteriostasis rates, drug concentration is converted into logarithm, then based on Sun Yunpei's Method
Calculate the toxicity index of each medicament and the co-toxicity coefficient of mixture etc..
TTI=TIA×PA+TIB×PB
ATI: mixture surveys toxicity index:
S: the EC of standard antiseptic agent50∶
M: the EC of mixture50∶
TTI: mixtures theoretical toxicity index:
TIA: A medicament toxicity index:
PA: percentage composition of the A medicament in mixture:
TIB: B medicament toxicity index:
PB: percentage composition of the B medicament in mixture:
CTC: co-toxicity coefficient.
5, test result
Respectively it the results are shown in Table 1 with the toxicity test for comparing rice sheath blight disease.
Respectively compounding matches the toxicity test for comparing rice sheath blight disease to table 1
After fluxapyroxad and oxine-copper composite, each group compounding agent still has rice sheath blight disease prevents and kill off activity well.
The EC of 11 proportions50Between 1.275-2.646, wherein the active highest of proportion 1:1.
Fluxapyroxad is shown in Table 2 with the synergy evaluation result for comparing rice sheath blight disease with respectively compounding for copper 8-hydroxyquinolinate.
2 fluxapyroxad of table is evaluated with respectively compounding for copper 8-hydroxyquinolinate with the synergy for comparing rice sheath blight disease
Fluxapyroxad and copper 8-hydroxyquinolinate all have superior control efficiency, fluxapyroxad, copper 8-hydroxyquinolinate to rice sheath blight disease
To the bacteriostatic activity EC of rice sheath blight disease50Respectively 1.969mg/L and 3.274mg/L.
After fluxapyroxad and oxine-copper composite, each group compounding agent prevents and kill off activity to what rice sheath blight disease showed synergy.
The EC of 11 proportions50Between 1.275-2.646, wherein the active highest of proportion 1:1.The co-toxicity coefficient of 11 proportions exists
Between 82.3-192.9, different ratio all has synergistic effect to rice sheath blight disease controlling, wherein fluxapyroxad: copper 8-hydroxyquinolinate is matched
When than for 1:1, synergistic effect is most strong.
The field efficacy of the prevention and treatment rice sheath blight disease of test example 2
Test objective: to understand field of the fluxapyroxad of different ratio with oxine-copper composite preparation to rice sheath blight disease
Application effect determines optimal use proportion and usage amount.
Subjects: rice sheath blight disease
For studying object: rice (rich late 347)
Test site: the Hefei City, Anhui Province hilllock market town village Qian Feng.
Test medicine is shown in Table 3.
3 test medicine of table
Cell arrangement: random alignment, each cell 30m2, 3 repetitions.
Application method: spray-on process is routinely used.On April 28th, 2015 starts to be administered, and is administered 2 times altogether, is spaced 7d.Per acre
30 kilograms of water consumption, CK sprays equivalent clear water.It is primary in investigation on May 22nd, 2015.
Investigation method: taking 5 points of samplings, and every investigation is connected 5 clumps, investigates 25 clumps of rice altogether, records total strain number, diseased plant number
And disease index, calculate disease index and preventive effect.Severity Scaling takes 0,1,3,5,7,9 grade of totally 6 rank.
Disease scale is as follows:
0 grade: complete stool is disease-free；
1 grade: quaterfoil and its following leaf sheath, blade morbidity (with sword-like leave for first leaf)；
3 grades: third blade and its following leaf sheath, blade morbidity；
5 grades: second blades and its following leaf sheath, blade morbidity；
7 grades: sword-like leave blade and its following folic acid, blade morbidity；
9 grades: complete stool morbidity, it is withered ahead of time.
Drug effect calculation method:
Disease index (%)=[∑ (the morbidity numbers at different levels × disease series)]/(investigation sum × highest series) × 100
Opposite control efficiency (%)=(control disease index-processing disease index)/control disease index × 100
Biological statistical method: Notable difference test uses " DMRT " method.
The test result of the fluxapyroxad compound preparation prevention and treatment rice sheath blight disease of different ratio is shown in Table 4.
The test result of the fluxapyroxad compound preparation prevention and treatment rice sheath blight disease of 4 different ratio of table
Note: lowercase letter indication difference significance degree is P=0.05, and capitalization indicates that significant difference degree is P=
0.01。
Field control effectiveness test shows: the fluxapyroxad of different ratio and the compound preparation of copper 8-hydroxyquinolinate are right under experimental concentration
Rice sheath blight disease has favorable effect, and 1000 times of liquid of better than 33.5% copper 8-hydroxyquinolinate suspending agent, 42.4% azoles ether flutolanil are outstanding
800 times of liquid of agent are floated to the control efficiency of rice sheath blight disease, wherein 40% 1000 times of fluxapyroxad copper 8-hydroxyquinolinate suspending agent (1:1)
Liquid is best to rice sheath blight disease preventive effect, reaches 98.04%.
1000-2000 times of liquid prevention and treatment rice of 40% fluxapyroxad copper 8-hydroxyquinolinate suspending agent (1:1) is recommended to use in production
Banded sclerotial blight carries out even spraying to rice using spray method, and continuous spraying is twice.Rain is met in 6 hours after application, is waited after becoming a fine day
It should fill spray primary.
Claims (10)
1. a kind of disease-resistant composition pesticide, it is characterised in that: be made of fluxapyroxad and copper 8-hydroxyquinolinate.
2. disease-resistant composition pesticide described in accordance with the claim 1, it is characterised in that: count in mass ratio, fluxapyroxad: quinoline
Copper=1-99:1-99.
3. disease-resistant composition pesticide according to claim 2, it is characterised in that: count in mass ratio, fluxapyroxad: quinoline
Copper=1-49:1-24.
4. disease-resistant composition pesticide described in accordance with the claim 3, it is characterised in that: count in mass ratio, fluxapyroxad: quinoline
Copper=1:1.
5. a kind of method for preparing any one of claim 1-4 disease-resistant composition pesticide, which is characterized in that activity at
It is added in point on pesticidal preparations and is prepared into various pesticidal preparations after acceptable auxiliary material.
6. according to the method for claim 5, which is characterized in that the auxiliary material includes emulsifier, wetting dispersing agent, thickening
Any one of agent, antifreezing agent, stabilizer, preservative, disintegrating agent, binder or filler；Preferably, the emulsifier is selected from
Nonionic surfactant castor oil ethylene oxide adduct, nonylphenol polyoxyethylene ether, fatty alcohol polyoxyethylene ether, phenethyl
One of phenol polyethenoxy polyethenoxy ether, APES formaldehyde condensation product are a variety of；The wetting dispersing agent
Selected from lauryl sodium sulfate, pull open powder, alkylphenol-polyethenoxy base ether, naphthalene sulfonic acid-formaldehyde condensation product salt or polyoxyethylene groups
The mixture that one or more of polyoxypropylene ether block copolymers are formed according to arbitrary proportion；The thickener is selected from
One of xanthan gum, carboxymethyl cellulose, Sodium Polyacrylate, aluminum magnesium silicate, gaseous silicon oxide or attapulgite are a kind of
The mixture formed above according to arbitrary proportion；The antifreezing agent is selected from ethylene glycol, propylene glycol, glycerol, glycerol-ether diglycol
Or any one or more than one mixture formed according to arbitrary proportion in methyl propylene diglycol；The stabilizer
In 2,6 di tert butyl 4 methyl phenol or citric acid or butylated hydroxy anisole it is any one or more than one according to
The mixture of arbitrary proportion composition；The disintegrating agent in urea, bentonite, montmorillonite or sodium alginate any one or
More than one mixtures formed according to arbitrary proportion；The binder is selected from gelatin, Arabic gum, xanthan gum, trimerization phosphorus
One of sour sodium, phenolic resin or polyvinylpyrrolidone or more than one mixtures formed according to arbitrary proportion；It is described
Filler be kaolin.
7. according to the method for claim 5, which is characterized in that the pesticidal preparations include suspending agent, wettable powder,
Water dispersible granules, microemulsion, emulsifiable concentrate or aqueous emulsion.
8. according to the method for claim 7, which is characterized in that the preparation method of the agricultural chemicals suspension agent, comprising: by fluorine azoles
Bacterium amide, copper 8-hydroxyquinolinate are uniformly mixed with wetting agent, dispersing agent, antifreeze, preservative and thickener, defoaming agent and water, grinding, then
Suspending agent is obtained after thickener and defoaming agent adjusting uniformly is added；
The preparation method of the microemulsion, comprising: dissolving fluxapyroxad, copper 8-hydroxyquinolinate in solvent and emulsifier becomes
Deionized water is added under stiring and forms WO emulsion for oily phase, then agitated phase inversion is cooled to room temperature at oil-in-water type,
Filtering obtains microemulsion；
The preparation method of the pesticide emulsion in water, comprising: be dissolved into fluxapyroxad, copper 8-hydroxyquinolinate in solvent and emulsifier
Even oil phase；Deionized water, antifreeze, preservative, defoaming agent are mixed into uniform water phase, under high speed shear, by water phase
Oily phase is added, obtains aqueous emulsion；
The preparation method of the pesticide water dispersible granules, comprising: by fluxapyroxad, copper 8-hydroxyquinolinate and wetting agent, dispersing agent and fill out
Material carries out co-grinding, is granulated after adding water kneading, then obtains water dispersible granules through drying, screening；
The preparation method of the pesticide wettable, comprising: fluxapyroxad, copper 8-hydroxyquinolinate are mixed with auxiliary agent and filler, passed through
After ultra-fine grinding, it is uniformly mixed up to wettable powder；
The preparation method of the emulsifiable concentrates for agricultural chemicals agent, comprising: fluxapyroxad, copper 8-hydroxyquinolinate are dissolved in organic solvent, added
The transparent liquid of individual event is made to get emulsifiable concentrate in emulsifier, mixed dissolution.
9. purposes of any one of the claim 1-4 disease-resistant composition pesticide in controlling plant diseases.
10. purposes according to claim 9, which is characterized in that the plant disease is rice sheath blight disease.
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| CN201811201464.3A CN109258686A (en) | 2018-10-16 | 2018-10-16 | Disease-resistant composition pesticide and its preparation method and application |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101631465A (en) * | 2007-02-05 | 2010-01-20 | 巴斯夫欧洲公司 | Fungicidal mixtures comprising substituted 1-methylpyrazol-4-ylcarboxanilides |
| CN109169675A (en) * | 2018-09-29 | 2019-01-11 | 陕西上格之路生物科学有限公司 | A kind of bactericidal composition of Fluxapyroxad-containsterilization and copper 8-hydroxyquinolinate |
-
2018
- 2018-10-16 CN CN201811201464.3A patent/CN109258686A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101631465A (en) * | 2007-02-05 | 2010-01-20 | 巴斯夫欧洲公司 | Fungicidal mixtures comprising substituted 1-methylpyrazol-4-ylcarboxanilides |
| CN109169675A (en) * | 2018-09-29 | 2019-01-11 | 陕西上格之路生物科学有限公司 | A kind of bactericidal composition of Fluxapyroxad-containsterilization and copper 8-hydroxyquinolinate |
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| 伍均锋，: "《农药安全使用技术》", 31 October 2016, 河北科学技术出版社， * |
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Address after: 318000 Sha Wai Industrial Zone, Jiaojiang District, Zhejiang, Taizhou Applicant after: Shunyi Co., Ltd Address before: Jiaojiang District of Taizhou City, Zhejiang province 318000 road outside No. 97 Applicant before: Zhejiang Haizheng Chemical Co., Ltd. |
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