CN109212175A

CN109212175A - Sample analyser

Info

Publication number: CN109212175A
Application number: CN201810688653.1A
Authority: CN
Inventors: 刘隐明; 吴万; 谢子贤
Original assignee: Shenzhen Mindray Bio Medical Electronics Co Ltd; Shenzhen Mindray Scientific Co Ltd
Current assignee: Shenzhen Mindray Bio Medical Electronics Co Ltd; Shenzhen Mindray Scientific Co Ltd
Priority date: 2017-06-30
Filing date: 2018-06-28
Publication date: 2019-01-15
Anticipated expiration: 2038-06-28
Also published as: CN114295815A; CN109212175B

Abstract

The present invention discloses a kind of sample analyser, including shell, first partition, crossbeam, reaction component and sampling component.Shell includes the first side plate being oppositely arranged and the second side plate and the third side plate and the 4th side plate that are relatively connected between the first side plate and the second side plate.First partition is connected between the first side plate and the second side plate, forms the first space between first partition and the 4th side plate.Crossbeam is installed on first partition, and crossbeam includes opposite first end and second end, and first end is located in the first space, and second end passes through the first side plate to stretch out the first space.Reaction component is contained in the first space and is located at the lower section of crossbeam.Sampling component includes sampler, and sampler is mounted on crossbeam and can move between the first and second ends.Sample analyser topology layout of the present invention is reasonable.

Description

Sample analyser

Technical field

The present invention relates to the field of medical instrument technology more particularly to a kind of sample analysers.

Background technique

With the increase of the diversified demand to cellanalyzer analytic function, the required portion being arranged of cellanalyzer Part is more and more, so that cellanalyzer inner space is more nervous, increases the topology layout difficulty of cellanalyzer. If topology layout is unreasonable, it is easy to cause that the test speed of cellanalyzer is low, security reliability is poor.

Summary of the invention

Technical problem to be solved by the present invention lies in provide a kind of reasonable sample analyser of topology layout.

To achieve the goals above, embodiment of the present invention adopts the following technical scheme that

A kind of sample analyser is provided, comprising:

Shell including the first side plate and the second side plate that are oppositely arranged and is relatively connected to first side plate and institute State the third side plate and the 4th side plate between the second side plate；

First partition is connected between first side plate and second side plate, the first partition and the described 4th The first space is formed between side plate；

Crossbeam is installed on the first partition, and the crossbeam includes opposite first end and second end, the first end position In in first space, the second end passes through first side plate to stretch out first space；

Reaction component is contained in first space and is located at the lower section of the crossbeam；And

Sampling component, including sampler, the sampler are mounted on the crossbeam and can be in the first ends and institute It states and is moved between second end.

Wherein, the sample analyser further includes second partition, and the second partition is connected to first side plate and institute It states between the second side plate, forms second space between the second partition and the third side plate.

Preferably, first space is greater than the second space.

Wherein, the sampling component further include the first liquid valve group for being installed on the second partition, hydrostatic sensor and First syringe, the first liquid valve group are set to the second space, and first syringe and the hydrostatic sensor are set to In the second space and it is located at below the first liquid valve group.

Wherein, the sample analyser further includes driving assembly, and the driving component is for driving the sample analyser In flow path, the driving component is located in first space.

Wherein, the driving component includes the air accumulator group and air pump set on first space, and the air pump connects institute Air accumulator group is stated, for setting up attention pressure and negative pressure for the air accumulator.

Wherein, the sample analyser further includes pressure detecting plate, between the air accumulator group and first side plate Distance be greater than the distance between the air accumulator group and second side plate, the pressure detecting plate be set to the air accumulator group and Between second side plate, the pressure detecting plate is used to detect the pressure of the air accumulator group.

Wherein, the air accumulator group includes the first air accumulator and the second air accumulator, and the air pump is in first air accumulator The first positive pressure is inside established, the air pump establishes the first negative pressure in second air accumulator.

Wherein, the air accumulator group further includes third air accumulator and the 4th air accumulator, described in the third air accumulator connection First air accumulator, so that first positive pressure establishes the second positive pressure, the 4th air accumulator connection in the third air accumulator First air accumulator or the third air accumulator, so that first positive pressure or the second positive pressure are built-in in the 4th air accumulator Vertical third positive pressure, the third positive pressure are different from second positive pressure.

Wherein, the sample analyser further includes the 5th air accumulator, and the 5th air accumulator is set in first space And be located at below the air pump, the 5th air accumulator connects second air accumulator, so that first negative pressure is described the The second negative pressure is established in five air accumulators.

Wherein, the sample analyser further includes building pressure pipe road, and the first end for building pressure pipe road connects the air pump and goes out Mouthful, the second end for building pressure pipe road connects the air accumulator group, and the pipeline extends from the first end to the second end When, first walk pipe downward walks pipe upward again.

Wherein, float is set in the air accumulator group, the float is used to that feed liquor alarm to occur in the air accumulator group.

Wherein, the sample analyser further includes the first air valve group, and the first air valve group is for controlling the air accumulator Building in group presses work, and the first air valve group is located in first space.

Wherein, the sample analyser further includes liquid storage tank group and the second liquid valve group, and the liquid storage tank is mounted on described One space and it is located at below the air accumulator group, the second liquid valve group is used to control perfusion and the liquid feeding of the liquid storage tank group, The second liquid valve group is between the first partition and the liquid storage tank group.

Wherein, the liquid storage tank group includes the first liquid storage tank, the second liquid storage tank, third syringe and the first constant displacement pump Group, the third syringe are used to that liquid to be perfused for the first liquid storage tank, and the third syringe is located at the first partition and institute It states between the first liquid storage tank, the described first quantitative pump group is connected between second liquid storage tank and the reaction component.

Wherein, the liquid storage tank group further includes the second constant displacement pump, and second constant displacement pump is connected to first constant displacement pump Between group and second liquid storage tank, for providing spare liquid for the reaction component.

Wherein, the sample analyser further includes opening-closing plate, and the opening-closing plate is rotatablely connected second side plate and is located at Between the first partition and the 4th side plate, the opening-closing plate is for installing the liquid storage tank group.

Wherein, the sample analyser further includes reagent group, and the reagent group participates at biological sample for storing The reagent of reason, the reagent group are installed on the second partition and are located in the second space.

Wherein, the reagent group includes multiple reagents, first switch valve, second switch valve, the first pipeline and Two pipelines, the first switch valve is for connecting positive pressure source, and first piping connection is in the multiple reagent and described the Between one switch valve, the second switch valve for connecting negative pressure source, second piping connection the multiple reagent with Between the second switch valve.

Wherein, the reagent group further includes a plurality of first branch and a plurality of second branch, a plurality of first branch one One is accordingly connected between the multiple reagent and first pipeline, is provided in every first branch unidirectional Valve, a plurality of second branch is connected to correspondingly between the multiple reagent and second pipeline, described in every Check valve is provided in second branch.

Wherein, the sample analyser further includes that third liquid valve group and second quantify pump group, the third liquid valve group and institute It states the second quantitative pump group to be connected between the reagent group and the reaction component, the third liquid valve group is set to described second Space and it is located at below the reagent group.

Wherein, the sample analyser further include be connected to it is a plurality of between the third liquid valve group and the reaction component Third pipeline, third pipeline described in single include sequentially connected first part, coupling part and second part, and described first Part connects the third liquid valve group, and the second part connects the reaction component, and the reaction component is located at the third Below liquid valve group, the first difference in height is formed between the both ends of the first part, forms the between the both ends of the second part Two differences in height, the coupling part is for preventing bubble from entering the first part from the second part.

Wherein, the volume of the first part is less than the volume of constant displacement pump in the described second quantitative pump group.

Wherein, the sample analyser further includes the second air valve group, the second air valve group connect the liquid storage tank group and The reagent group, second air valve be mounted on the second space and be located at the reagent group and first side plate it Between.

Wherein, the sample analyser further includes reagent connector and the 4th liquid valve group, and the reagent connector is fixed on described Second side plate, the reagent connector are used to reagent inputting the reagent group, and the 4th liquid valve group is connected to the reagent Between connector and the reagent group.

Wherein, the sample analyser further includes optocoupler detection components, and the optocoupler detection components are connected to the reagent Between connector and the 4th liquid valve group, the optocoupler detection components are located at below the 4th liquid valve group.

Wherein, the reaction component includes the first reaction tank, the second reaction tank, third reaction tank and the 4th reaction tank, First reaction tank is used to form the first prepare liquid that detection hemoglobin counts, and second reaction tank is used to form detection Second prepare liquid of white blood cell count(WBC), the third reaction tank is used to form the third prepare liquid of detection leukocyte differential count, described 4th reaction tank is used to form the 4th prepare liquid of detection red blood cell count(RBC).

Wherein, in the second end of the crossbeam on the direction of the first end, first reaction tank, described Two reaction tanks, the third reaction tank and the 4th reaction tank are successively arranged.

Wherein, the reaction component further includes the 5th reaction tank, the 5th reaction tank be used to form detection net knit it is red thin The 5th prepare liquid that born of the same parents count, the 5th reaction tank are set between the third reaction tank and the 4th reaction tank.

Wherein, the second prepare liquid is also used to detect erythroblast classification and basophilic granulocyte classification.

Wherein, the sample analyser further includes the first liquid valve and third constant displacement pump, and the first liquid valve is connected to described Between first reaction tank and the third constant displacement pump, the first liquid valve and the third constant displacement pump are set to first space Liquid level lower section that is interior and being located at first reaction tank.

Wherein, the sample analyser further includes flow chamber and the second syringe, and it is empty that the flow chamber is set to described first Between and be located above the crossbeam, second syringe is set to the lower section in the shell and being located at the flow chamber.

Wherein, the sample analyser further includes third partition, and the third partition is set to first space and connection Between the first partition and the third side plate, the flow chamber is set to above the third partition；The sample analysis Instrument further includes being set to air pump described in the air pump in first space to be set to below the third partition.

Wherein, the reaction component includes the second reaction tank, third reaction tank and the 5th reaction tank, second reaction Pond is used to form the second prepare liquid of detection white blood cell count(WBC), and the third reaction tank is used to form the of detection leukocyte differential count Three prepare liquids, the 5th reaction tank are used to form the 5th prepare liquid of detection reticulocyte count；

The sample analyser further includes the 4th pipeline, and the flow chamber connects the first access point of the 4th pipeline, Second reaction tank connects the second access point of the 4th pipeline, and the third reaction tank connects the of the 4th pipeline Three access points, the 5th reaction tank connect the 4th access point of the 4th pipeline, and first access point, described second connect Access point, the third access point and the 4th access point are sequentially arranged on the 4th pipeline.

Wherein, the sample analyser further includes breaking the third air valve group that valve group is broken described in valve group and control, described It breaks valve group to be connected between the flow chamber and the reaction component, the third air valve is mounted on first space and position Below the reaction component.

Wherein, the sample analyser further includes liquid waste processing component, and the liquid waste processing component is installed on described second Partition and be located at the second space in, the liquid waste processing component includes spaced first waste liquid pool and the second waste liquid Pond, liquid pump and the 5th liquid valve group, first waste liquid pool and the liquid pump are located at below the 5th liquid valve group, and described second Waste liquid pool is between the 5th liquid valve group and second side plate.

Wherein, the liquid waste processing component further includes connecting line, the second liquid valve, liquid level sensor and delays time to control Device, the connecting line are connected between second waste liquid pool and first waste liquid pool, and the second liquid valve is arranged in institute It states on connecting line, the liquid level sensor is set to second waste liquid pool, and the liquid level sensor is for detecting described second The liquid level of waste liquid in waste liquid pool, the delay controller couples the liquid level sensor and the second liquid valve, described Delay controller is used for when the liquid level is reduced to preset value, and delay preset time cuts off the second liquid valve, so that It is liquid in the part pipeline of the connecting line, in the pipeline of part is gas.Alternatively, the liquid waste processing component further includes connecting Road, the second liquid valve and optocoupler detection sensor are taken over, the connecting line is connected to second waste liquid pool and gives up with described first Between liquid pool, the second liquid valve is arranged on the connecting line, and the optocoupler detection sensor is set to the connecting line, When the optocoupler detection sensor detects that gas occurs in connecting line, the second liquid valve stops working so that the connecting tube It is liquid in the part pipeline on road, in the pipeline of part is gas.Wherein, the cover board is located at first side plate far from described The side of two side plates, the cover board fasten first side plate to form third space, and the dyestuff component is located at the third In space.

Wherein, the dyestuff component includes that dyestuff bag group, third quantify pump group and the 6th liquid valve group, and the third is quantitative Pump group and the 6th liquid valve group are located above the dyestuff bag group.

Wherein, the sample analyser further includes cover board and preheating component, and it is remote that the cover board is located at first side plate Side from second side plate, the cover board fasten first side plate to form third space, the preheating component peace On first side plate and it is located in the third space.

Wherein, the 4th space is formed between the first partition and the second partition, the 4th space is for arranging The circuit trace of the sample analyser.

Preferably, the sample analyser further includes the 4th partition, and the periphery of the 4th partition connects first side Plate, second side plate, the third side plate and the 4th side plate simultaneously be located at the 4th space above, the described 4th every Plate is used for bearer circuit plate and component；

4th partition includes fixed part and the movable part for being rotatablely connected the fixed part, and the movable part is for covering Or the 4th space described in open section.

Compared to the prior art, the invention has the following advantages:

Sample analyser described in the embodiment of the present invention, since sampler described in its can be in the first end of the crossbeam It is moved between the second end, the reaction component is located at the below the crossbeam, therefore the sampler can be in the shell It is external acquire biological sample, then fast moved to the direction of the first end to the reaction component along the second end Top distributes the biological sample to the reaction component, and the sampling of the sampler and dispensing rate are very fast.In short, The sample analyser is improved described by the position of crossbeam described in rational deployment, the sampler and the reaction component The topology layout of the test speed of sample analyser, the sample analyser is reasonable.

Detailed description of the invention

In order to illustrate more clearly of technical solution of the present invention, attached drawing needed in embodiment will be made below Simply introduce, it should be apparent that, the accompanying drawings in the following description is only some embodiments of the present invention, general for this field For logical technical staff, without creative efforts, other attached drawings can also be obtained such as these attached drawings.

Fig. 1 is a kind of structural schematic diagram of sample analyser provided in an embodiment of the present invention.

Fig. 2 is the schematic block diagram of the members of sample analyser shown in Fig. 1.

Fig. 3 is the optical cable of sample analyser shown in Fig. 1.

Fig. 4 is the partial structure diagram of sample analyser shown in Fig. 1.

Fig. 5 is another part structural schematic diagram of sample analyser shown in Fig. 1.

Fig. 6 is the schematic diagram at another visual angle of structure shown in Fig. 5.

Fig. 7 is the schematic diagram of another part-structure of sample analyser shown in Fig. 1.

Fig. 8 is the schematic diagram of yet another part-structure of sample analyser shown in Fig. 1.

Fig. 9 is the schematic diagram of another part-structure of sample analyser shown in Fig. 1.

Figure 10 is the part-structure connection relationship diagram one of sample analyser shown in Fig. 1.

Figure 11 is the part-structure connection relationship diagram two of sample analyser shown in Fig. 1.

Figure 12 is the part-structure connection relationship diagram three of sample analyser shown in Fig. 1.

Figure 13 A is the schematic diagram of the third liquid valve group of sample analyser shown in Fig. 1 and a kind of connection type of reaction component.

Figure 13 B is the signal of the third liquid valve group of sample analyser shown in Fig. 1 and another connection type of reaction component Figure.

Figure 13 C is the signal of the third liquid valve group of sample analyser shown in Fig. 1 and another connection type of reaction component Figure.

Figure 13 D is showing for the third liquid valve group of sample analyser shown in Fig. 1 and still another connection type of reaction component It is intended to.

Figure 13 E is showing for the third liquid valve group of sample analyser shown in Fig. 1 and the again another connection type of reaction component It is intended to.

Figure 14 is the part-structure connection relationship diagram four of sample analyser shown in Fig. 1.

Figure 15 is the part-structure connection relationship diagram five of sample analyser shown in Fig. 1.

Figure 16 is the part-structure connection relationship diagram six of sample analyser shown in Fig. 1.

Specific embodiment

With reference to the accompanying drawing, embodiments herein is described.

Also referring to Fig. 1 to Fig. 8, the embodiment of the present invention provides a kind of sample analyser 100.The sample analyser 100 can be used for carrying out biological sample analysis, and the biological sample can be blood etc..The sample analyser 100 further includes driving Dynamic component 1, sampling component 2, reaction component 3, detection components 4, liquid waste processing component 5 and controller 6.The driving component 1 For driving the various flow paths (including gas circuit and fluid path) in the sample analyser 100.The sampling component 2 for acquire and Distribute biological sample.The reaction component 3 is for handling to form prepare liquid the biological sample.The detection components 4 for detecting the prepare liquid to form detection information.The liquid waste processing component 5 is for collecting and discharging the sample analysis Waste liquid in instrument 100.The controller 6 is used to control the workflow of the sample analyser 100 and handles the detection letter Breath is to form analysis result.

The sample analyser 100 further includes shell 71, first partition 721 and crossbeam 73.The shell 71 includes phase The first side plate 711 and the second side plate 712 to setting and relatively it is connected to first side plate 711 and second side plate Third side plate 713 and the 4th side plate 714 between 712.The first partition 721 be connected to first side plate 711 with it is described Between second side plate 712.The first space 741 is formed between the first partition 721 and the 4th side plate 714.The crossbeam 73 are installed on the first partition 721.The crossbeam 73 includes opposite first end 731 and second end 732, the first end 731 are located in first space 741, and the second end 732 passes through first side plate 711 to stretch out first space 741.The crossbeam 73 extends to the second end 732 from the first end 731, namely extremely from the internal stretch of the shell 71 The outside of the shell 71.The reaction component 3 is contained in first space 741 and is located at the lower section of the crossbeam 73.Institute Stating sampling component 2 includes sampler 21 (such as sampling needle), and the sampler 21 is mounted on the crossbeam 73 and can be in institute It states and is moved between first end 731 and the second end 732.

In the present embodiment, since the sampler 21 can be in the first end 731 of the crossbeam 73 and described the It is moved between two ends 732, the reaction component 3 is located at 73 lower section of crossbeam, therefore the sampler 21 can be in the shell It is external acquire biological sample, then fast moved to the direction of the first end 731 to the reaction along the second end 732 The top of component 3 distributes the biological sample to the reaction component 3, the sampling of the sampler 21 and dispensing rate compared with Fastly.In short, the sample analyser 100 passes through crossbeam 73, the sampler 21 and the reaction group described in rational deployment The position of part 3 improves the test speed of the sample analyser 100, and the topology layout of the sample analyser 100 is reasonable.

Optionally, the shell 71 further includes the top plate 715 and bottom plate 716 being oppositely arranged, first side plate 711, institute State the second side plate 712, the third side plate 713 and the 4th side plate 714 be arranged in end to end the top plate 715 with Between the bottom plate 716, the shell 71 encloses the space for setting out a relative closure, for arranging the sample analyser 100 Most of structure.The two boards of the shell 71 being arbitrarily oppositely arranged can be arranged substantially in parallel, any phase of the shell 71 Two boards even substantially vertical can be arranged.The first partition 721 is oppositely arranged with the 4th side plate 714.

Optionally, the sample analyser 100 further includes second partition 722.The second partition 722 is connected to described It is empty that second is formed between side plate 711 and second side plate 712, between the second partition 722 and the third side plate 713 Between 742.At this point, first space 741 is arranged with the second space 742 interval.

First space 741 is greater than the second space 742.Each component of the sample analyser 100 can be according to certainly Body product and mutual connection relationship are neatly laid out in first space 741 with the second space 742.Such as it is big Volume component may be selected to be arranged in first space 741.

Also referring to Fig. 1 to Fig. 9, as a kind of alternative embodiment, the sampling component 2 further includes being installed on described The first liquid valve group 81, hydrostatic sensor 22 and the first syringe 23 of two partitions 722.The first liquid valve group 81 is set to described Second space 742, first syringe 23 and the hydrostatic sensor 22 are set in the second space 742 and are located at institute State 81 lower section of the first liquid valve group.First syringe 23 is set to 81 lower section of the first liquid valve group, helps to avoid gas Bubble and easy exhaust bubble.The hydrostatic sensor 22 can be located at 23 top of the first syringe and be located at the first liquid valve group 81 lower sections.The first liquid valve group 81 includes at least two liquid valves.The first liquid valve group 81 is for coordinating the sampling component 2 Sampling and divide sample to act.

Optionally, the sampling component 2 further includes the first constant displacement pump 91, and first constant displacement pump 91 is set to described second In space 742 and it is located at 81 lower section of the first liquid valve group.First constant displacement pump 91 is set to 81 lower section of the first liquid valve group It helps to avoid bubble and is easy exhaust bubble.First constant displacement pump 91 connects the sampler 21, and described first is quantitative 91 connection diluent reagent bucket of pump, interior can have a certain amount of dilution.The absorption of sampler 21 had diluted primary Biological sample after, dilution in first constant displacement pump 91 can carry out the biological sample in the sampler 21 secondary Dilution.Dilution in first constant displacement pump 91 can be used for rinsing the pipeline of sampling component 2.Those skilled in the art can Understand, if you do not need to doing secondary dilution to biological sample, it may not be necessary to the first constant displacement pump 91.

Also referring to Fig. 1 to Figure 11, as a kind of alternative embodiment, the driving component 1 is located at first space In 741.The biggish the driving component 1 of overall volume is set to biggish first space 741 of volume, is conducive to raising pair The space utilization rate in first space 741, so that sample analyser internal structure arrangement is more reasonable.

The driving component 1 of the sample analyser 100 includes 11 He of air accumulator group set on first space 741 Air pump 12.The air pump 12 connects the air accumulator group 11, for establishing positive pressure and negative pressure for the air accumulator group 11.The gas Pump 12 is set to the lower section of the air accumulator group 11.The air accumulator group 11 and one that the air pump 12 is the driving component 1 Point.

In use, the air pump 12 is in the air accumulator group 11 built-in attention pressure and negative pressure, the positive pressure and the negative pressure For: drive the sampling component 2 to acquire biological sample；And/or drive the reaction component 3 handle the biological sample with Form prepare liquid；And/or the detection components 4 is driven to detect the prepare liquid to form detection information.

In the present embodiment, the sample analyser 100 is using the air pump 12 and air accumulator group 11 of small size as main Power resources reduce the cost of the sample analyser 100.100 high concentration of the sample analyser layout gas circuit and liquid Road, while accomplishing gas-liquid separation as far as possible, and the component stringent to bubble requirement is avoided to generate bubble as far as possible.Due to the air accumulator 11 volumes of group are larger, therefore the air accumulator group 11 is set to first space 741, more reasonably to utilize the sample point The inner space of analyzer 100.

Optionally, the top in first space 741 is arranged in the air accumulator group 11, even if the also air accumulator group 11 Against the top setting, thus as far as possible in the sample analyser 100 fluid path and circuit be isolated, make the sample analyser 100 Security reliability is higher.

Optionally, the sample analyser 100 further includes pressure detecting plate 13.The air accumulator group 11 and first side The distance between plate 711 is greater than the distance between the air accumulator group 11 and described second side plate 712, the pressure detecting plate 13 Between the air accumulator group 11 and second side plate 712, the pressure detecting plate 13 is for detecting the air accumulator group 11 pressure.The pressure detecting plate 13 is equipped with pressure sensor.At this point, the pressure detecting plate 13 and the air accumulator group The distance between 11 very littles, adapter tube between the two is very short, so that the pressure detecting plate 13 being capable of real time reaction gas tank Pressure change.

Optionally, the air accumulator group 11 includes the first air accumulator 111 and the second air accumulator 112, and the air pump 12 is in institute It states and establishes the first positive pressure in the first air accumulator 111, the air pump 12 establishes the first negative pressure in second air accumulator 112.Institute It states the first positive pressure and first negative pressure can be used for driving various flow paths (including gas circuit and liquid in the sample analyser 100 Road).Optionally, the air pump 12 is positioned as close to first air accumulator 111 and second air accumulator 112 setting, with Shorten the pipeline between the air pump 12 and first air accumulator 111 and second air accumulator 112, to reduce flow resistance. First positive pressure can be 120KPa, and first negative pressure can be -40KPa.

Optionally, the air accumulator group 11 further includes third air accumulator 113 and the 4th air accumulator 114.The third gas storage Tank 113 connects first air accumulator 111, so that first positive pressure establishes the second positive pressure in the third air accumulator 113. 4th air accumulator 114 connects first air accumulator 111, so that first positive pressure is in the 4th air accumulator 114 Third positive pressure is established, the third positive pressure is different from second positive pressure.Second positive pressure and the third positive pressure are respectively less than First positive pressure.Second positive pressure and the third positive pressure can be used for driving different flow paths.Second positive pressure and described The building of third positive pressure, which presses through journey, to carry out simultaneously, can also separate and carry out.Second positive pressure can be 90KPa, the third positive pressure It can be 50KPa.It will be appreciated by those skilled in the art that can also the 4th air accumulator 114 connect the third air accumulator 113, so that second positive pressure establishes third positive pressure in the 4th air accumulator 114.

Optionally, the sample analyser 100 further includes the 5th air accumulator 115.5th air accumulator 115 is set to described In first space 741 and it is located at 12 lower section of air pump, the 5th air accumulator 115 connects second air accumulator 112, so that First negative pressure establishes the second negative pressure in the 5th air accumulator 115.Second negative pressure can be -30kPa.Due to described 5th air accumulator 115 is badly in need of will be using second negative pressure as a source of power (such as red blood cell detection), while also needing to receive Collect waste liquid (such as red blood cell detects generated waste liquid), therefore the 5th air accumulator 115 is arranged under the air pump 12 Side, the 5th air accumulator 115 also is located at 11 lower section of air accumulator group at this time, to realize that gas-liquid is isolated.

Optionally, the sample analyser 100 further includes building pressure pipe road 116.The first end 1161 for building pressure pipe road 116 It connects the air pump 12 to export, the second end 1162 for building pressure pipe road 116 connects the air accumulator group 11, and the pipeline is from institute When stating first end 1161 and extending to the second end 1162, first walk pipe downward walks pipe upward again.Due to the compression of the air pump 12 There may be condensed waters for air, therefore when the pipeline extends from the first end 1161 to the second end 1162, first downward It walks pipe and walks pipe upward again, condensed water can be avoided to flow back to the air pump 12 when the air pump 12 is idle, and then keep away Exempt from the air pump 12 to fail.Without liquid in first air accumulator 111 and second air accumulator 112.

Optionally, float 117 is set in the air accumulator group 11, the float 117 in the air accumulator group 11 for sending out Raw feed liquor alarm.For example, first air accumulator 111, second air accumulator 112 and the third air accumulator The float 117 is provided in 113, if liquid enter first air accumulator 111, second air accumulator 112 with And in the third air accumulator 113, the float 117 can then float and alarm, to prevent liquid from entering in air pump 12.At it In his embodiment, the float 117 may also set up in the 4th air accumulator 114.

Optionally, the sample analyser 100 further includes the first air valve group 101, and the first air valve group 101 is for controlling Building in the air accumulator group 11 presses work, and the first air valve group 101 is located in first space 741.First gas Valve group 101 can be set to the lower section of the air accumulator group 11 and be arranged as close as possible to the air accumulator group 11, so as to shorten adapter tube Length reduces flow resistance and flow loss.The first air valve group 101 includes at least two air valves.

Also referring to Fig. 1 to Figure 10, as a kind of alternative embodiment, the sample analyser 100 further includes liquid storage tank Group 20 and the second liquid valve group 82.The liquid storage tank group 20 is set to first space 741 and is located at 11 lower section of air accumulator group. The second liquid valve group 82 is used to control perfusion and the liquid feeding of the liquid storage tank group 20, and the second liquid valve group 82 is located at described the Between one partition 721 and the liquid storage tank group 20.The second liquid valve group 82 is mountable to the first partition 721.Described Two liquid valve groups 82 include at least two liquid valves.

Optionally, the liquid storage tank group 20 includes the first liquid storage tank 201 and the second liquid storage tank 202, the sample analyser 100 further include third syringe 203 and the first quantitative pump group 92.Storage is for carrying out optics in first liquid storage tank 201 The sheath fluid of sheath fluid measurement, the sheath fluid can be dilution.Storage is for carrying out other measurements or clear in second liquid storage tank 202 The dilution washed.The third syringe 203 is used to that liquid to be perfused for the first liquid storage tank 201.The third syringe 203 is located at Between the first partition 721 and first liquid storage tank 201.The third syringe 203 can be in first liquid storage tank 201 It is the perfusion of the first liquid storage tank 201 supplement liquid during for other component feed flow.First liquid storage tank 201 connects institute State third air accumulator 113.The third air accumulator 113 is connected to first liquid storage tank 201, to pass through second positive pressure The sheath fluid in first liquid storage tank 201 is driven to flow out (to flow chamber 41).Described first quantitative pump group 92 is connected to described the Between two liquid storage tanks 202 and the reaction component 3.Described first quantitative pump group 92 can be used for will be in second liquid storage tank 202 Dilution be quantitatively supplied to the reaction component 3.Described first quantitative pump group 92 includes at least two constant displacement pumps.

Optionally, the liquid storage tank group 20 further includes the second constant displacement pump 93.Second constant displacement pump 93 is connected to described Between a certain amount of pump group 92 and second liquid storage tank 202, for providing spare liquid for the reaction component 3.When described When dilution in two liquid storage tanks 202 is enough, second liquid storage tank 202 is that the reaction component 3 provides liquid；When described When dilution deficiency in two liquid storage tanks 202, second constant displacement pump 93 is that the reaction component 3 provides spare liquid.It is described Second constant displacement pump 93 is located in the first space 741.Second constant displacement pump 93 is located at two constant displacement pumps of the first quantitative pump group 92 Between.

Optionally, the sample analyser 100 further includes opening-closing plate 75.The opening-closing plate 75 is rotatablely connected described second side Plate 712 and between the first partition 721 and the 4th side plate 714, the opening-closing plate 75 is for installing the liquid storage Pond group 20.5th air accumulator 115 can also be set on the opening-closing plate 75.The rotatable setting of the opening-closing plate 75 is so that institute The component arrangement stated in sample analyser 100 is more flexible.

Also referring to Fig. 1 to Figure 13 D, as a kind of alternative embodiment, the sample analyser 100 further includes reagent Group 30, the reagent group 30 are used to store the reagent for participating in biological sample processing (such as dilution, reaction).The reagent group 30 are installed on the second partition 722 and are located in the second space 742.For convenience of the reagent flow in the reagent group 30 Enter the reaction component 3, the reagent group 30 can be arranged above the reaction component 3.

Optionally, the reagent group 30 includes multiple reagents 301.The sample analyser 100 further includes first opening Close valve 302, second switch valve 303, the first pipeline 304 and the second pipeline 305.The first switch valve 302 is for connecting just Potential source (such as described 4th air accumulator 114 for forming the third positive pressure).First pipeline 304 is connected to the multiple examination Between agent pond 301 and the first switch valve 302.The second switch valve 303 (such as forms described for connecting negative pressure source 5th air accumulator 115 of two negative pressure).Second pipeline 305 is connected to the multiple reagent 301 and the second switch valve Between 303.In use, the second switch valve 303 is connected, the multiple reagent 301 is made to be connected to negative pressure source, the outer reagent of machine Reagent enters the multiple reagent 301 under difference effect in bucket；Then the second switch valve 303 is closed, and described first opens It closes valve 302 to be connected, so that the multiple reagent 301 is connected to positive pressure source, reagent is in differential pressure action in the multiple reagent 301 Lower inflow reaction component 3 participates in biological sample treatment process.

In the present embodiment, since the common first switch valve 302 and described second of the multiple liquid storage tank group 20 is opened Valve 303 is closed, therefore reduces the cost of the sample analyser 100.Meanwhile it being connected just with the first switch valve 302 respectively Potential source connects negative pressure source with the second switch valve 303, can reduce the sample analyser 100 and occurs to intersect carrying pollution Risk.Furthermore it is entered in the second switch valve 303 to reduce a small amount of foam reverse irrigation, it can be in the second switch valve Increase isolation ward 310 between 303 and second pipeline 305, the isolation ward 310 can play the role of buffering.

Optionally, the reagent group 30 further includes a plurality of first branch 306 and a plurality of second branch 307.It is described a plurality of The first branch 306 is connected to correspondingly between the multiple reagent 301 and first pipeline 304, and every described Check valve 308 is provided on one branch 306.The a plurality of second branch 307 is connected to the multiple reagent correspondingly Between pond 301 and second pipeline 305, check valve 308 is provided in every second branch 307.In the present embodiment In, due to being provided with check valve 308 in the first branch 306 described in every, list is provided in every second branch 307 To valve 308, therefore it can reduce the sample analyser 100 and occur to intersect the risk for carrying pollution.

Optionally, the sample analyser 100 further includes third liquid valve group 83 and the second quantitative pump group 94.The third liquid Valve group 83 and the second quantitative pump group 94 are connected between the reagent group 30 and the reaction component 3.The third liquid Valve group 83 is set to the second space 742 and is located at 30 lower section of reagent group.The third liquid valve group 83 includes at least two A liquid valve.The third liquid valve group 83 is used to coordinate the process of the reagent group 30 liquid feeding in the reaction component 3.It is described Second quantitative pump group 94 includes at least two constant displacement pumps.Described second quantitative pump group 94 is used for quantitatively by the reagent group 30 In reagent input in the reaction component 3.Second constant displacement pump 93 can be set to the second space 742 and be located at described the Three liquid valve groups, 83 lower section.

Optionally, the sample analyser 100 further include be connected to the third liquid valve group 83 and the reaction component 3 it Between a plurality of third pipeline 831.Third pipeline 831 described in single includes sequentially connected first part 8311, coupling part 8312 and second part 8313.The first part 8311 connects the third liquid valve group 83.The second part 8313 connects The reaction component 3 is connect, the reaction component 3 is located at 83 lower section of third liquid valve group.The both ends of the first part 8311 Between form the first difference in height, the second difference in height, the coupling part 8312 are formed between the both ends of the second part 8313 For preventing bubble from entering the first part 8311 from the second part 8313.Wherein, the body of the first part 8311 Product is smaller than the volume of constant displacement pump in the described second quantitative pump group 94.

In the present embodiment, since the difference in height between the third liquid valve group 83 and the reaction component 3 is divided into institute The first difference in height and second difference in height are stated, the value of first difference in height and second difference in height is smaller, can drop The low first part 8311 and the respective bubble accumulative risk of the second part 8313, and 8312 energy of the coupling part It enough prevents bubble from entering the first part 8311 from the second part 8313, further reduced the first part 8311 Bubble accumulative risk, therefore can be avoided between the third liquid valve group 83 and the reaction component 3 because there are single big Difference in height and the problem of cause bubble to be accumulated, the bubble in the third pipeline 831 can be excluded completely as much as possible.

Optionally, as shown in Figure 13 A to 13D, the coupling part 8312 can be horizontal pipeline, inclination pipeline, circle shape pipe Road or check valve.When the coupling part 8312 is inclination pipeline (as shown in Figure 13 B), the coupling part 8312 connects described The height of the end of first part 8311 connects the height of the end of the first part 8311 lower than the coupling part 8312.

Optionally, as shown in figure 13e, the coupling part 8312 can also be two-port valve, opens and connects when two-port valve energization When logical, the third liquid valve group 83 is toward 3 liquid feeding of reaction component, and at the end of liquid feeding, the power-off of two-port valve valve, which is closed, to be cut off, in liquid A small amount of bubble has crossed valve, accumulates in the second part 8313；Next third liquid valve group 83 again toward 3 liquid feeding of reaction component when, institute It states bubble in second part 8313 and is just discharged to reaction component 3, circuit sequentially, not will lead to a large amount of bubble accumulations in third pipeline In 831.

Optionally, in the multiple reagent 301 between the first switch valve 302 the first farthest reagent of distance In be stored with dilution.Since dilution is to the influence very little of the reagent (such as hemolytic agent) in other reagents, even if having few Amount dilution flows backward into other reagents 301, and the influence to measurement is also little.Simultaneously as certain low types of matching are not used In first reagent of storage dilution, first reagent setting is also facilitated into closing first reagent in end Pond.

Optionally, the sample analyser 100 further includes the second air valve group 102.The second air valve group 102 connects described Liquid storage tank group 20 and the reagent group 30, the second air valve group 102 are set to the second space 742 and are located at the reagent Between pond group 30 and first side plate 711.The second air valve group 102 includes at least two air valves.The second air valve group 102 can be used for participating in coordinating the flow path movement of the liquid storage tank group 20 and the reagent group 30.The second air valve group 102 is also It can be used for participating in coordinating the movement of the described first quantitative pump group 92 and the second quantitative pump group 94.The second air valve group 102 It may be provided at the higher position in the second space 742, to meet gas-liquid isolation requirement.302 He of first switch valve The second switch valve 303 may also be arranged in the second air valve group 102.

Optionally, the sample analyser 100 further includes reagent connector 309 and the 4th liquid valve group 84.The reagent connector 309 are fixed on second side plate 712, to facilitate piping connection, the reagent connector 309 is used to reagent inputting the examination Agent pond group 30.The 4th liquid valve group 84 is connected between the reagent connector 309 and the reagent group 30.4th liquid Valve group 84 includes at least two liquid valves.The 4th liquid valve group 84 is used to coordinate that the dynamic of reagent to be perfused to the reagent group 30 Make.

Optionally, the sample analyser 100 further includes optocoupler detection components 3010.The optocoupler detection components 3010 connect It connects between the reagent connector 309 and the 4th liquid valve group 84, the optocoupler detection components 3010 are located at the 4th liquid 84 lower section of valve group.The optocoupler detection components 3010 are used to detect in the pipeline for being used for transmission reagent with the presence or absence of bubble.

Also referring to Fig. 1 to Fig. 8, as a kind of alternative embodiment, the reaction component 3 include the first reaction tank 31, Second reaction tank 32, third reaction tank 33 and the 4th reaction tank 34.First reaction tank 31 is used to form the blood red egg of detection The first prepare liquid that white (hemoglobin, HGB) is counted.Second reaction tank 32 is used to form the of detection white blood cell count(WBC) Two prepare liquids.The third reaction tank 33 is used to form detection leucocyte (white blood cell count, WBC) classification Third prepare liquid.4th reaction tank 34 be used to form detection red blood cell (Red Blood Cell, RBC) count the 4th to Survey liquid.

Optionally, the detection components 4 further include the first detector and the second detector.First detector is set to institute The first reaction tank 31 is stated, for detecting first prepare liquid by photoelectric colorimeter method.Second detector is set to described 4th reaction tank 34, for passing through the 4th prepare liquid described in electrical impedance method detection.

Optionally, in the second end 732 of the crossbeam 73 on the direction of the first end 731, described first is anti- Pond 31, second reaction tank 32, the third reaction tank 33 and the 4th reaction tank 34 is answered successively to arrange.Second is to be measured Liquid can also be used to detect erythroblast classification and basophilic granulocyte classification.Time measured due to second prepare liquid Number is most, and second reaction tank 32 carries out the biological sample distribution prior to the third reaction tank 33, therefore described Second reaction tank 32 is compared the third reaction tank 33 and is arranged close to the second end 732.

Optionally, the reaction component 3 further includes the 5th reaction tank 35, and the 5th reaction tank 35 is used to form detection net The 5th prepare liquid of red blood cell (Ret) counting is knitted, the 5th reaction tank 35 is set to the third reaction tank 33 and the described 4th Between reaction tank 34.It since 35 frequency of use of the 5th reaction tank is lower, or even does not use, therefore the 5th reaction tank 35 It compares second reaction tank 32 and the third reaction tank 33 is arranged close to the first end 731.

Optionally, the sample analyser 100 further includes the first liquid valve 85 and third constant displacement pump 95, the first liquid valve 85 It is connected between first reaction tank 31 and the third constant displacement pump 95, the first liquid valve 85 and the third constant displacement pump 95 It is set in first space 741 and is located at below the liquid level of first reaction tank 31.Due to 85 He of the first liquid valve The third constant displacement pump 95 is located at below the liquid level of first reaction tank 31, therefore connects the first liquid valve 85 and described the Three constant displacement pumps 95 simultaneously for for first reaction tank 31 add reagent pipeline in be constantly in barotropic state, can be avoided because Pipeline is ventilative and generates bubble.Meanwhile the first liquid valve 85 and the third constant displacement pump 95 are close to first reaction tank 31 settings, can shorten the length of above-mentioned pipeline, so that the liquid after measurement in above-mentioned pipeline can update completely every time, because This, which can be avoided, accumulates bubble in above-mentioned pipeline.

Also referring to Fig. 1 to Figure 14, as a kind of alternative embodiment, the sample analyser 100 further includes flow chamber 41 and second syringe 42.The flow chamber 41 and second syringe 42 are a part of the detection components 4.The inspection Surveying component 4 further includes third detector, and the third detector is set to 41 exit of flow chamber, to pass through optical detection It detects prepare liquid (such as second prepare liquid and/or the third prepare liquid and/or described 5th prepare liquid).The flowing Room 41 is set to first space 741 and is located at 73 top of crossbeam, and second syringe 42 is set in the shell 71 And it is located at the lower section of the flow chamber 41.Second syringe 42 can be used for prepare liquid preparing section being pushed into the flow chamber 41 To be detected.Second syringe 42, which is set to below the flow chamber 41, can be avoided generation bubble.

Optionally, the sample analyser 100 further includes the 7th liquid valve group 86.The 7th liquid valve group 86 is connected to described Between flow chamber 41 and first liquid storage tank 201 for storing sheath fluid.The 7th liquid valve group 86 is arranged in the flowing 41 side of room (such as 41 lower section of the flow chamber), to facilitate connection while make full use of space.The 7th liquid valve group 86 includes At least two liquid valves.

Optionally, the flow chamber 41 is set to region top in first space 741.For example, the flow chamber 41 It can be set between the air accumulator group 11 and first side plate 711.

Optionally, the sample analyser 100 further includes third partition 723.The third partition 723 is set to described first It space 741 and is connected between the first partition 721 and the third side plate 713, the flow chamber 41 is set to the third 723 top of partition, the air pump 12 are set to 723 lower section of third partition.At this point, the flow chamber 41 divides with the air pump 12 The two sides up and down of the third partition 723 are not set, can be reduced to mutual interference.The third partition 723 with it is described Top plate 715 is oppositely arranged.

With reference to Figure 14, in one embodiment, the reaction component 3 includes the second reaction tank 32, third reaction tank 33 And the 5th reaction tank 35.Second reaction tank 32 is used to form the second prepare liquid of detection white blood cell count(WBC), the third Reaction tank 33 be used to form detection leukocyte differential count third prepare liquid, the 5th reaction tank 35 be used to form detection net knit it is red 5th prepare liquid of cell count.The sample analyser 100 further includes the 4th pipeline 411, and the flow chamber 41 connects described First access point 4111 of the 4th pipeline 411, second reaction tank 32 connect the second access point of the 4th pipeline 411 4112, the third reaction tank 33 connects the third access point 4113 of the 4th pipeline 411, the 5th reaction tank 35 connection 4th access point 4114 of the 4th pipeline 411, first access point 4111, second access point 4112, described Three access points 4113 and the 4th access point 4114 are sequentially arranged on the 4th pipeline 411.Instead due to described second It answers the type measured needed for the prepare liquid in pond 32 more and the assignment order of biological sample is forward, therefore described second connects Spacing between access point 4112 and first access point 4111 is minimum.Since the frequency of use of the 5th reaction tank 35 is low, It does not use even, therefore the spacing between the 4th access point 4114 and first access point 4111 is maximum.

Optionally, the sample analyser 100 further includes breaking the third gas that valve group 50 is broken described in valve group 50 and control Valve group 87.The valve group 50 that breaks is connected between the flow chamber 41 and the reaction component 3.It is described to break the use of valve group 50 Air pressure driving (such as being driven by first positive pressure in first air accumulator 111), can reduce and described break valve group 50 Pollution risk to the prepare liquid for flowing to the flow chamber 41 by the reaction component 3.The valve group 50 that breaks is close to the stream Dynamic room 41 is arranged, and to shorten the length for connecting the pipeline for breaking valve group 50 and the flow chamber 41, reduces prepare liquid Preparation amount.The third air valve group 87 is set to first space 741 and is located at 3 lower section of reaction component.The third gas After valve group 87 breaks the setting of valve group 50 described in, it can shorten and break valve group with described for connecting the third air valve group 87 The length of 50 tracheae reduces air consumption to reduce flow resistance.

Also referring to Fig. 1 to Figure 15, as a kind of alternative embodiment, at the waste liquid of the sample analyser 100 Reason component 5 is installed on the second partition 722 and is located in the second space 742.The liquid waste processing component 5 includes interval The first waste liquid pool 51 and the second waste liquid pool 52, liquid pump 53 and the 5th liquid valve group 88 being arranged.First waste liquid pool 51 and institute It states liquid pump 53 and is located at 88 lower section of the 5th liquid valve group, second waste liquid pool 52 is located at the 5th liquid valve group 88 and described the Between two side plates 712.Subnormal ambient is formed in first waste liquid pool 51, for collecting the big portion of the sample analyser 100 Divide waste liquid.Second waste liquid pool 52 is connected to atmosphere, for collecting the waste liquid being discharged by positive pressure driving (such as by the flow chamber The flowed out waste liquid in 41 outlets).Second waste liquid pool 52 connects first waste liquid pool 51, and first waste liquid pool 51 connects Second waste liquid pool 52, the liquid pump 53 connect first waste liquid pool 51.Waste liquid enters institute in second waste liquid pool 52 The first waste liquid pool 51 is stated then to be emitted into outside machine by the liquid pump 53.The volume of first waste liquid pool 51 can be greater than described second The volume of waste liquid pool 52.The 5th liquid valve group 88 includes at least two liquid valves, for coordinating the receipts of the liquid waste processing component 5 Collect waste liquid and discharges the movement of waste liquid.

Optionally, as shown in figure 16, in another embodiment, second waste liquid pool 52 can not also be passed by liquid level Sensor 54 and delays time to control unit 61 solve the problems, such as foam overflow, can in second waste liquid pool 52 and first waste liquid Optocoupler detection sensor 62 is set on the connecting line 55 between pond 51, when the second waste liquid pool 52 is to 51 drain of the first waste liquid pool Cheng Zhong, optocoupler detection sensor 62 start to detect, when detecting that signal becomes bubble from liquid in optocoupler, control described second Liquid valve 89 stops drain, at this point, a part is foam in connecting line 55, a part is liquid, the part in the second waste liquid pool Foam is discharged, and avoids constantly accumulating foam in second waste liquid pool 52.

Optionally, the liquid waste processing component 5 further include connecting line 55, the second liquid valve 89, liquid level sensor 54 and Delay controller 61.The connecting line 55 is connected between second waste liquid pool 52 and first waste liquid pool 51.It is described Second liquid valve 89 is arranged on the connecting line 55.The liquid level sensor 54 is set to second waste liquid pool 52, the liquid Level sensor 54 is used to detect the liquid level of the waste liquid in second waste liquid pool 52.The delay controller 61 couples described Liquid level sensor 54 and the second liquid valve 89, the delay controller 61 are used to be reduced to preset value in the liquid level When, delay preset time cuts off the second liquid valve 89, so as to be liquid in the part pipeline of the connecting line 55, part is managed It is gas in road.The second liquid valve 89 can be one of liquid valve in the 5th liquid valve group 88.The second liquid valve 89 Can also be used and valve is broken by air pressure driving, to avoid because in waste liquid impurity it is excessive due to block the second liquid valve 89, lead to institute The second liquid valve 89 is stated to break down.The delay controller 61 may be formed in the controller 6.First waste liquid pool 51 with The connecting line 55 (such as sebific duct) between second waste liquid pool 52 is longer.The preset value be equal to zero or close to Zero.

In the present embodiment, it is described when first waste liquid pool 51 needs to extract the waste liquid in second waste liquid pool 52 Second liquid valve 89 is connected to first waste liquid pool 51 and second waste liquid pool 52, and the waste liquid in second waste liquid pool 52 is being pressed It is extracted in first waste liquid pool 51 under difference effect.When the liquid level is reduced to the preset value, the delay The second liquid valve 89, which is controlled, after control unit delay preset time disconnects second waste liquid pool 52 and first waste liquid pool 51, so that the waste liquid in second waste liquid pool 52 has been drained off, but there is also about half in the connecting line 55 (for preventing first waste liquid pool 51 to be connected to atmosphere or positive pressure source by second waste liquid pool 52), in addition liquid does not empty Half is then foam, so that when each first waste liquid pool 51 extracts waste liquid in second waste liquid pool 52, it is described Foam in second waste liquid pool 52 is all drained off a part (including at least the part for entering above-mentioned pipeline), to avoid described Foam is constantly accumulated in second waste liquid pool 52, solves the problems, such as the foam overflow of second waste liquid pool 52.

Optionally, the liquid waste processing component 5 further includes for that will clean discharging of waste liquid caused by swab to described the Another liquid pump of one waste liquid pool 51.

Also referring to Fig. 1 to Figure 15, as a kind of alternative embodiment, the sample analyser 100 further includes cover board 76. The cover board 76 is located at side of first side plate 711 far from second side plate 712, and the cover board 76 fastens described first Side plate 711 is to form third space 743.The rotation connection of cover board 76 snaps connection first side plate 711.

Optionally, the sample analyser 100 further includes dyestuff component 60, and it is empty that the dyestuff component 60 is located at the third Between in 743.Dyestuff in the dyestuff component 60 can be used for participating in biological sample treatment process.Due to required dye in measuring every time Expect less, dyestuff consumption is slow, and there is no need to the liquid storage tanks of the setting storage dyestuff in the sample analyser 100.It will be described Dyestuff component 60 is set to the third space 743, can quickly and easily replace dye set by rotating or dismantling the cover board 76 Dyestuff bag in part 60.

The dyestuff component 60 quantifies pump group 96 and the 6th liquid valve group 89, the third including dyestuff bag group 601, third Quantitative pump group 96 and the 6th liquid valve group 89 are located at 601 top of dyestuff bag group.The dyestuff bag group 601 includes at least two A dyestuff bag.It includes at least two constant displacement pumps that the third, which quantifies pump group 96,.The 6th liquid valve group 89 includes at least liquid valve.Institute State the distribution movement that third quantifies pump group 96 and the 6th liquid valve group 89 is used to coordinate the dyestuff bag group 601.

Optionally, the sample analyser 100 further includes preheating component 70.The preheating component 70 is mounted on described On first side plate 711 and it is located in the third space 743.

Also referring to Fig. 1 to Fig. 9, as a kind of alternative embodiment, the sample analyser 100 further includes sample introduction platform 80.The sample introduction platform 80 is located at side of first side plate 711 far from second side plate 712 and is located at the crossbeam 73 Lower section.The sample introduction platform 80 is for placing and transmitting the test tube for holding biological sample.

Also referring to Fig. 1 to Figure 15, as a kind of alternative embodiment, the first partition 721 and the second partition The 4th space 744 is formed between 722.Circuit trace of 4th space 744 for the sample analyser 100 of arranging.Institute It is mountable in institute to state the component (such as constant displacement pump, air valve, liquid valve etc.) that required electricity consumption is driven in sample analyser 100 It states in first partition 721 and the second partition 722.

Optionally, the sample analyser 100 further includes the 4th partition 724.The periphery of 4th partition 724 connects institute It states the first side plate 711, second side plate 712, the third side plate 713 and the 4th side plate 714 and is located at described the Four spaces, 744 top, the 4th partition 724 are used for bearer circuit plate and component.4th partition 724 and the top plate 715 are oppositely arranged and between the top plate 715 and the bottom plate 716.The controller 6 may be provided at the 4th partition On 724.

4th partition 724 includes fixed part 7241 and the movable part 7242 for being rotatablely connected the fixed part 7241, institute State movable part 7242 for cover or open section described in the 4th space 744.It, can quick portion by rotating the movable part 7242 Divide the 4th space 744, so that convenient cabling and/or component in the 4th space 744 is safeguarded.

The sample analyser of the embodiment of the present application has sampling component, reaction component, detection components, liquid waste processing component With the pipeline of the electricity between components and component such as driving assembly, air-liquid, wherein fluid path is driven to gas-powered, power source From the air pump being located inside analyzer, cooperate the air accumulator of multiple and different pressure, constitutes the main dynamic of entire analyzer fluid path Power source not only can guarantee performance requirement, but also can reduce cost.It closes the position of each component of the sample analyser of the embodiment of the present application The design of the electricity, air-liquid pipeline of system and inter-module, topology layout is reasonable, farthest utilizes space, is meeting sample Analyzer multi-parameter, high speed design requirement under the premise of, small volume, cost is relatively low.

The embodiment of the present invention has been described in detail above, specific case used herein to the principle of the present invention and Embodiment is expounded, and the above description of the embodiment is only used to help understand the method for the present invention and its core ideas； At the same time, for those skilled in the art can in specific embodiments and applications according to the thought of the present invention There is change place, in conclusion the contents of this specification are not to be construed as limiting the invention.

Claims

1. a kind of sample analyser characterized by comprising

Shell including the first side plate and the second side plate that are oppositely arranged and is relatively connected to first side plate and described the Third side plate and the 4th side plate between two side plates；

First partition is connected between first side plate and second side plate, the first partition and the 4th side plate Between form the first space；

Crossbeam is installed on the first partition, and the crossbeam includes opposite first end and second end, and the first end is located at institute It states in the first space, the second end passes through first side plate to stretch out first space；

Sampling component, including sampler, the sampler are mounted on the crossbeam and can be in the first ends and described the It is moved between two ends.

2. sample analyser as described in claim 1, which is characterized in that the sample analyser further includes second partition, institute It states second partition to be connected between first side plate and second side plate, between the second partition and the third side plate Form second space；

Preferably, first space is greater than the second space.

3. sample analyser as claimed in claim 2, which is characterized in that the sampling component further includes being installed on described second The first liquid valve group, hydrostatic sensor and the first syringe of partition, the first liquid valve group is set to the second space, described First syringe and the hydrostatic sensor are set in the second space and are located at below the first liquid valve group.

4. sample analyser as described in claim 1, which is characterized in that the sample analyser further includes driving assembly, institute Driving assembly is stated for driving the flow path in the sample analyser, the driving component is located in first space.

5. sample analyser as claimed in claim 4, which is characterized in that the driving component includes being set to first space Air accumulator group and air pump, the air pump connect the air accumulator group, for setting up attention pressure and negative pressure for the air accumulator.

6. sample analyser as claimed in claim 5, which is characterized in that the sample analyser further includes pressure detecting plate, The distance between the air accumulator group and first side plate are greater than the distance between the air accumulator group and second side plate, The pressure detecting plate is set between the air accumulator group and second side plate, and the pressure detecting plate is for detecting the storage The pressure of gas tank group.

7. sample analyser as claimed in claim 5, which is characterized in that the air accumulator group includes the first air accumulator and second Air accumulator, the air pump establish the first positive pressure in first air accumulator, and the air pump is established in second air accumulator First negative pressure.

8. sample analyser as claimed in claim 7, which is characterized in that the air accumulator group further includes third air accumulator and Four air accumulators, the third air accumulator connects first air accumulator, so that first positive pressure is in the third air accumulator Establish the second positive pressure, the 4th air accumulator connects first air accumulator or the third air accumulator, so that described first just Pressure or the second positive pressure establish third positive pressure in the 4th air accumulator, and the third positive pressure is different from second positive pressure.

9. sample analyser as claimed in claim 7, which is characterized in that the sample analyser further includes the 5th air accumulator, 5th air accumulator is set in first space and is located at below the air pump, the 5th air accumulator connection described second Air accumulator, so that first negative pressure establishes the second negative pressure in the 5th air accumulator.

10. such as the described in any item sample analysers of claim 5~9, which is characterized in that the sample analyser further includes building Pressure pipe road, the first end for building pressure pipe road connect the air pump outlet, and the second end for building pressure pipe road connects the gas storage Tank group, when the pipeline extends from the first end to the second end, first walk pipe downward walks pipe upward again.

11. such as the described in any item sample analysers of claim 5~9, which is characterized in that float is set in the air accumulator group, The float is used to that feed liquor alarm to occur in the air accumulator group.

12. such as the described in any item sample analysers of claim 5~9, which is characterized in that the sample analyser further includes the One air valve group, the first air valve group press work for controlling building in the air accumulator group, and the first air valve group is located at institute It states in the first space.

13. such as the described in any item sample analysers of claim 5~9, which is characterized in that the sample analyser further includes storage Liquid pool group and the second liquid valve group, the liquid storage tank are mounted on first space and are located at below the air accumulator group, and described the Two liquid valve groups are used to control perfusion and the liquid feeding of the liquid storage tank group, the second liquid valve group be located at the first partition with it is described Between liquid storage tank group.

14. sample analyser as claimed in claim 13, which is characterized in that the liquid storage tank group includes the first liquid storage tank and the Two liquid storage tanks, the sample analyser further include third syringe and the first quantitative pump group, and the third syringe is for being Liquid is perfused in first liquid storage tank, and the third syringe is between the first partition and first liquid storage tank, and described the A certain amount of pump group is connected between second liquid storage tank and the reaction component.

15. sample analyser as claimed in claim 14, which is characterized in that the liquid storage tank group further includes the second constant displacement pump, Second constant displacement pump is connected between the described first quantitative pump group and second liquid storage tank, for mentioning for the reaction component For spare liquid.

16. sample analyser as claimed in claim 13, which is characterized in that the sample analyser further includes opening-closing plate, institute It states opening-closing plate and is rotatablely connected second side plate and positioned at the first partition and the 4th side plate between, the opening-closing plate use In the installation liquid storage tank group.

17. sample analyser as claimed in claim 2, which is characterized in that the sample analyser further includes reagent group, institute It states reagent group and is installed on the second partition for storing the reagent for participating in biological sample processing, the reagent group and is located at In the second space.

18. sample analyser as claimed in claim 17, which is characterized in that the reagent group includes multiple reagents, institute Stating sample analyser further includes first switch valve, second switch valve, the first pipeline and the second pipeline, and the first switch valve is used In connection positive pressure source, between the multiple reagent and the first switch valve, described second opens first piping connection Valve is closed for connecting negative pressure source, second piping connection is between the multiple reagent and the second switch valve.

19. sample analyser as claimed in claim 18, which is characterized in that the reagent group further includes a plurality of first branch With a plurality of second branch, a plurality of first branch be connected to correspondingly the multiple reagent and first pipeline it Between, check valve is provided in every first branch, a plurality of second branch is connected to the multiple correspondingly Between reagent and second pipeline, check valve is provided in every second branch.

20. such as the described in any item sample analysers of claim 17~19, which is characterized in that the sample analyser further includes Third liquid valve group and the second quantitative pump group, the third liquid valve group and the second quantitative pump group be connected to the reagent group with Between the reaction component, the third liquid valve group is set to the second space and is located at below the reagent group.

21. sample analyser as claimed in claim 20, which is characterized in that the sample analyser further include be connected to it is described A plurality of third pipeline between third liquid valve group and the reaction component, third pipeline described in single includes sequentially connected first Partially, coupling part and second part, the first part connect the third liquid valve group, described in the second part connection Reaction component, the reaction component are located at below the third liquid valve group, and it is high that first is formed between the both ends of the first part It is poor to spend, and the second difference in height is formed between the both ends of the second part, the coupling part is for preventing bubble from described second Part enters the first part.

22. sample analyser as claimed in claim 21, which is characterized in that the volume of the first part is less than described second The volume of constant displacement pump in quantitative pump group.

23. such as the described in any item sample analysers of claim 17~19, which is characterized in that the sample analyser further includes Second air valve group, the second air valve group connects the liquid storage tank group and the reagent group, second air valve are mounted on institute State second space and between the reagent group and first side plate.

24. such as the described in any item sample analysers of claim 17~19, which is characterized in that the sample analyser further includes Reagent connector and the 4th liquid valve group, the reagent connector are fixed on second side plate, and the reagent connector is used for reagent is defeated Enter the reagent group, the 4th liquid valve group is connected between the reagent connector and the reagent group.

25. sample analyser as claimed in claim 24, which is characterized in that the sample analyser further includes optocoupler detection group Part, the optocoupler detection components are connected between the reagent connector and the 4th liquid valve group, optocoupler detection components position Below the 4th liquid valve group.

26. sample analyser as described in claim 1, which is characterized in that the reaction component includes the first reaction tank, second Reaction tank, third reaction tank and the 4th reaction tank, first reaction tank are used to form first that detection hemoglobin counts Prepare liquid, second reaction tank are used to form the second prepare liquid of detection white blood cell count(WBC), and the third reaction tank is used for shape At the third prepare liquid of detection leukocyte differential count, the 4th reaction tank is used to form the 4th to be measured of detection red blood cell count(RBC) Liquid.

27. sample analyser as claimed in claim 26, which is characterized in that the crossbeam the second end to described On the direction of one end, first reaction tank, second reaction tank, the third reaction tank and the 4th reaction tank according to Secondary arrangement.

28. sample analyser as claimed in claim 27, which is characterized in that the reaction component further includes the 5th reaction tank, 5th reaction tank is used to form the 5th prepare liquid of detection reticulocyte count, and the 5th reaction tank is set to described the Between three reaction tanks and the 4th reaction tank.

29. such as the described in any item sample analysers of claim 26~28, which is characterized in that the second prepare liquid is also used to detect Erythroblast classification and basophilic granulocyte classification.

30. such as the described in any item sample analysers of claim 26~28, which is characterized in that the sample analyser further includes First liquid valve and third constant displacement pump, the first liquid valve are connected between first reaction tank and the third constant displacement pump, institute It states the first liquid valve and the third constant displacement pump is set in first space and is located at below the liquid level of first reaction tank.

31. sample analyser as described in claim 1, which is characterized in that the sample analyser further includes flow chamber and Two syringes, the flow chamber are set to first space and are located above the crossbeam, and second syringe is set to described Lower section in shell and positioned at the flow chamber.

32. sample analyser as claimed in claim 31, which is characterized in that the sample analyser further includes third partition, The third partition is set to first space and is connected between the first partition and the third side plate, the flow chamber Above the third partition；The sample analyser further includes being set to air pump described in the air pump in first space to be set to institute It states below third partition.

33. sample analyser as claimed in claim 31, which is characterized in that the reaction component includes the second reaction tank, the Three reaction tanks and the 5th reaction tank, second reaction tank is used to form the second prepare liquid of detection white blood cell count(WBC), described Third reaction tank be used to form detection leukocyte differential count third prepare liquid, the 5th reaction tank be used to form detection net knit it is red 5th prepare liquid of cell count；

The sample analyser further includes the 4th pipeline, and the flow chamber connects the first access point of the 4th pipeline, described Second reaction tank connects the second access point of the 4th pipeline, and the third that the third reaction tank connects the 4th pipeline connects Access point, the 5th reaction tank connect the 4th access point of the 4th pipeline, first access point, second access Point, the third access point and the 4th access point are sequentially arranged on the 4th pipeline.

34. such as the described in any item sample analysers of claim 31~33, which is characterized in that the sample analyser further includes Break and break the third air valve group of valve group described in valve group and control, it is described break valve group and be connected to the flow chamber reacted with described Between component, the third air valve is mounted on first space and is located at below the reaction component.

35. such as the described in any item sample analysers of claim 2~9, which is characterized in that the sample analyser further includes giving up Liquid processing component, the liquid waste processing component is installed on the second partition and is located in the second space, at the waste liquid Managing component includes spaced first waste liquid pool and the second waste liquid pool, liquid pump and the 5th liquid valve group, first waste liquid pool It is located at below the 5th liquid valve group with the liquid pump, second waste liquid pool is located at the 5th liquid valve group and described second side Between plate.

36. sample analyser as claimed in claim 35, which is characterized in that the liquid waste processing component further includes connecting tube Road, the second liquid valve, liquid level sensor and delay controller, the connecting line are connected to second waste liquid pool and described the Between one waste liquid pool, the second liquid valve is arranged on the connecting line, and the liquid level sensor is set to second waste liquid Pond, the liquid level sensor are used to detect the liquid level of the waste liquid in second waste liquid pool, and the delay controller couples The liquid level sensor and the second liquid valve, the delay controller are used for when the liquid level is reduced to preset value, The preset time that is delayed cuts off the second liquid valve, so as to be liquid in the part pipeline of the connecting line, in the pipeline of part be Gas.

37. sample analyser as claimed in claim 35, which is characterized in that the liquid waste processing component further includes connecting tube Road, the second liquid valve and optocoupler detection sensor, the connecting line are connected to second waste liquid pool and first waste liquid pool Between, the second liquid valve is arranged on the connecting line, and the optocoupler detection sensor is set to the connecting line, described When optocoupler detection sensor detects that gas occurs in connecting line, the second liquid valve stops working so that the connecting line It is liquid in the pipeline of part, in the pipeline of part is gas.

38. sample analyser as described in any one of claims 1 to 9, which is characterized in that the sample analyser further includes lid Plate and dyestuff component, the cover board are located at side of first side plate far from second side plate, described in the cover board fastens To form third space, the dyestuff component is located in the third space first side plate.

39. sample analyser as claimed in claim 38, which is characterized in that the dyestuff component includes dyestuff bag group, third Quantitative pump group and the 6th liquid valve group, the third quantifies pump group and the 6th liquid valve group is located above the dyestuff bag group.

40. sample analyser as described in any one of claims 1 to 9, which is characterized in that the sample analyser further includes lid Plate and preheating component, the cover board are located at side of first side plate far from second side plate, and the cover board fastens institute The first side plate is stated to form third space, the preheating component is mounted on first side plate and is located at the third space It is interior.

41. sample analyser as described in any one of claims 1 to 9, which is characterized in that the first partition and described second The 4th space, circuit trace of the 4th space for the sample analyser of arranging are formed between partition；

Preferably, the sample analyser further includes the 4th partition, and the periphery of the 4th partition connects first side plate, institute It states the second side plate, the third side plate and the 4th side plate and is located at the 4th space above, the 4th partition is used In bearer circuit plate and component；

4th partition includes fixed part and the movable part for being rotatablely connected the fixed part, and the movable part is for covering or opening Open part the 4th space.