CN207457252U - A kind of hemoglobin reaction unit and sample analyser - Google Patents

A kind of hemoglobin reaction unit and sample analyser Download PDF

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Publication number
CN207457252U
CN207457252U CN201721582883.7U CN201721582883U CN207457252U CN 207457252 U CN207457252 U CN 207457252U CN 201721582883 U CN201721582883 U CN 201721582883U CN 207457252 U CN207457252 U CN 207457252U
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hemoglobin
liquid
sample
reaction unit
wall surface
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CN201721582883.7U
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周慕昭
郁琦
李乐昌
万绍琦
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Abstract

The utility model is related to a kind of hemoglobin reaction unit and sample analysers, and including hemoglobin reaction tank, hemoglobin reaction tank is provided with to house the reaction chamber of biological sample and reagent;Reagent inlet for the waste liquid port for discharging waste liquid and for adding reagent, waste liquid outlet and reagent adding entrance are connected with reaction chamber;The one end open of reaction chamber is formed with the sample-adding opening entered suitable for sampling apparatus, and reaction chamber is added in for biological sample.Reaction tank upper end opening in the reaction unit and sample analyser facilitates sampling apparatus to enter reaction tank sample-adding and mixing, simplifies analyzer fluid path structure, be conducive to the detection of Trace Blood, and reduce instrument cost.

Description

A kind of hemoglobin reaction unit and sample analyser
Technical field
The utility model is related to the field of medical instrument technology, more particularly to a kind of hemoglobin reaction unit.
Background technology
In modern medical service Clinical Test Lab, the hemoglobin of Blood cell analyzer detection biological sample is used When (hemoglobin, HGB) is counted, the HGB reaction tanks of generally use closing, reagent and blood sample can only pass through designed pipeline It is added in reaction tank, i.e., is mixed and reacted with reagent in the reaction tank that blood sample is closed in reaction component, thus because needing Wanting the pipeline of individually designed addition reagent and blood sample can so that cellanalyzer is complicated, increase production cost.Meanwhile by It is few in micro-blood sample amount, it is impossible to which that by the way that blood valve is divided to carry out a point blood, therefore this HGB reaction tanks are unfavorable for Trace Blood detection.
Utility model content
Based on this, the utility model provides a kind of new hemoglobin reaction unit and to employ this hemoglobin anti- Answer the sample analyser of device.
According to the one side of the application, a kind of embodiment provides a kind of hemoglobin reaction unit, including:Hemoglobin Reaction tank, the hemoglobin reaction tank are provided with to house the reaction chamber of biological sample and reagent;For discharging waste liquid Waste liquid port and the reagent inlet for adding reagent, the waste liquid outlet and reagent adding entrance are connected with the reaction chamber; The one end open of the reaction chamber is formed with the sample-adding opening entered suitable for sampling apparatus, described in being added in for biological sample Reaction chamber.
In wherein a kind of embodiment, hemoglobin reaction unit further includes liquid collecting structure;The hemoglobin reaction tank Overflow port including being opened in setting height, the overflow port are communicated with the reaction chamber, for the reaction intracavity liquid mistake It is overflowed when more;The liquid collecting structure has liquid collecting cavity, and the liquid collecting cavity communicates with the overflow port, for storage or water conservancy diversion from institute State the liquid of overflow port spilling.
In wherein a kind of embodiment, the liquid collecting structure includes the collection set around the hemoglobin reaction tank outer wall Liquid disk, the catch tray have the liquid collecting cavity set around the hemoglobin reaction tank outer wall, and the entrance of the liquid collecting cavity is low In the overflow port.
In wherein a kind of embodiment, the liquid collecting cavity of the catch tray is equipped with liquid outlet, for by liquid guide flow to specifying Direction.
Liquid outlet described in a kind of embodiment has angularly disposed water conservancy diversion inclined-plane wherein.
In wherein a kind of embodiment, the overflow port is the opening for being arranged on the hemoglobin reaction tank side wall, institute The liquid flow outgoing direction of overflow port and the liquid outlet is stated towards same direction.
In wherein a kind of embodiment, the liquid collecting structure includes overflow pipe, described overflow pipe one end and the overflow port Connection, the other end is by liquid guide flow to setting position.
In wherein a kind of embodiment, the edge of the sample-adding opening is recessed to form the overflow port.
In wherein a kind of embodiment, the cavity wall of the hemoglobin reaction chamber includes the first wall surface and connection described first Second wall surface of wall surface, first wall surface include the first plane, the second plane, the first cambered surface and the second cambered surface, and described the One plane and second plane are oppositely arranged, and first cambered surface and second cambered surface are connected to described with being oppositely arranged Between one plane and second plane, second wall surface includes connecting the first end of first wall surface and away from described the The second end of one wall surface, second wall surface is collapsed in the first end on the direction of the second end, on the reaction tank Equipped with the reagent inlet for connecting the reaction chamber, the reagent inlet passes through second wall surface, first wall surface or described The junction of second wall surface and first wall surface.
According to the one side of the application, a kind of sample analyser is provided in a kind of embodiment, including sampling apparatus, liquid storage Device, the hemoglobin reaction unit shown in any one embodiment and detection device, the sampling apparatus are used for as previously described Collection analysis sample including sampling needle and drives the sampling needle driving portion for sampling needle movement, and the sampling needle driving portion drives The dynamic sampling needle acquisition blood sample, and it is assigned to the hemoglobin reaction unit;The device for storing liquid is for storage one Kind or a variety of hemoglobin detection reagents, the hemoglobin detection reagent are transported to the hemoglobin reaction dress by pipeline It puts, the pipeline connects the device for storing liquid and the hemoglobin reaction unit;The hemoglobin reaction unit is used for will The blood sample and the hemoglobin detection reagent are reacted;The detection device is used for the analysis sample and examination Result after agent reaction is detected to obtain hemoglobin testing result.
The utility model not only facilitates sampling apparatus into instead by carrying out opening design to hemoglobin reaction tank upper end Ying Chizhong sample-addings and mixing, and sample analyser fluid path structure is simplified, be conducive to Trace Blood detection;It is blood red to reduce closing The Chi Gai and sealing ring of albumen reaction tank, reduce instrument cost.
Description of the drawings
Fig. 1 show reaction tank in a kind of embodiment and is loaded hemoglobin reaction dress of the opening edge along recessed formation overflow port Put structure diagram;
It is the hemoglobin reaction unit structural representation of overflow port that Fig. 2, which show reaction tank sample-adding opening in a kind of embodiment, Figure;
Fig. 3 show the hemoglobin reaction unit structure diagram that liquid collecting structure in a kind of embodiment is overflow pipe;
Fig. 4 show the structure diagram of the reaction tank of hemoglobin reaction unit and sampling apparatus in a kind of embodiment.
Fig. 5 show the structure diagram that the reaction tank of hemoglobin reaction unit in a kind of embodiment shown in Fig. 4 is overlooked.
Fig. 6 show the structure diagram that the reaction tank of hemoglobin reaction unit in a kind of embodiment shown in Fig. 4 is splitted
Specific embodiment
The present invention is described in further detail below by specific embodiment combination attached drawing.Wherein different embodiments Middle similar component employs associated similar element numbers.In the following embodiments, many datail descriptions be in order to The application is better understood.However, those skilled in the art can be without lifting an eyebrow recognize, which part feature It is dispensed or can be substituted by other elements, material, method in varied situations.In some cases, this Shen Please relevant certain operations there is no in the description show or describe, this is the core in order to avoid the application by mistake More descriptions are flooded, and to those skilled in the art, be described in detail these relevant operations be not it is necessary, they The general technology knowledge of description and this field in specification can completely understand relevant operation.
In addition, feature described in this description, operation or feature can combine to form respectively in any suitable way Kind embodiment.Meanwhile each step in method description or action can also can be aobvious and easy according to those skilled in the art institute The mode carry out order exchange or adjustment seen.Therefore, the various orders in specification and drawings are intended merely to clearly describe a certain A embodiment is not meant to be necessary order, and wherein some sequentially must comply with unless otherwise indicated.
It is herein component institute serialization number itself, such as " first ", " second " etc., is only used for distinguishing described object, Without any order or art-recognized meanings.And " connection ", " connection " described in the application, unless otherwise instructed, include directly and It is indirectly connected with (connection).
Embodiment one
It please refers to Fig.1, the utility model embodiment provides a kind of hemoglobin reaction unit 100.The hemoglobin reacts Device 100, including hemoglobin reaction tank 10, hemoglobin reaction tank is provided with to house the reaction of biological sample and reagent Chamber 11;And the waste liquid port 16 for discharging waste liquid and the reagent inlet 15 for adding reagent, waste liquid outlet 16 and reagent enter Mouth 15 is connected with reaction chamber 11;The one end open of reaction chamber 11 is formed with what is entered suitable for sampling apparatus (such as sampling needle) Sample-adding opening 101 is added in for biological sample in reaction chamber 11.
This hemoglobin reaction unit 100 carries out opening design to 10 upper end of hemoglobin reaction tank, not only facilitates sampling Device enters sample-adding and mixing in reaction tank 10, and simplifies sample analyser fluid path structure, is conducive to Trace Blood detection;Subtract The Chi Gai of closing hemoglobin reaction tank and sealing ring (in existing sealed hemoglobin reaction unit generally use are lacked Component), reduce instrument cost.
Further, it is racetrack structure in the middle part of the present embodiment hemoglobin reaction tank, which is equivalent to cylinder Both sides are compressed to form two parallel side planes, and two planes are used to install monochromatic optical generator and receiver;Reaction tank Top is cylinder, and receiving liquid volume is big, can also play the role of preventing prepare liquid from overflowing.
Yet further, solve to be equipped with the hemoglobin reaction tank for being loaded opening since drain is not brought freely to be more effective Opening overflow the problem of, the present embodiment devises overflow port and liquid collecting structure, prevents liquid at adding mouth along reaction Pool wall is flowed out on two side planes for installing monochromatic optical generator and receiver, so as to avoid two side plane quilts The liquid pollution of outflow, influences testing result, improves instrument reliability.
In one embodiment, the sample-adding opening 101 of 10 one end of hemoglobin reaction tank connection reaction chamber 11 can be complete It is open or half opening or other shapes opening, sampling apparatus can stretch into and wherein be allocated sample.
Further, please refer to Fig.1, hemoglobin reaction tank 10 includes the overflow port 102 for being opened in setting height, overflow Mouthfuls 102 communicate with reaction chamber 11, for liquid in reaction chamber 11 it is excessive when overflow.Overflow port 102 can be reacted in hemoglobin When 10 drain of pond is not smooth, by liquid from reaction tank towards specific direction aerial drainage, liquid is avoided to be flowed out around from adding mouth 101 and dirty Contaminate 10 pool wall surrounding of reaction tank.
Further, hemoglobin reaction tank 10 further includes liquid collecting structure, and liquid collecting structure has liquid collecting cavity, and liquid collecting cavity is with overflowing Head piece communicates, for the liquid stored or water conservancy diversion is overflowed from overflow port.When there is liquid outflow in overflow port 102, extra liquid Cognition is flow in liquid collecting structure, avoids liquid along 10 pool wall flow detection device of reaction tank, pollution reaction tank 10 is used for installing Two side planes of monochromatic optical generator and receiver, influence testing result.
Please continue to refer to Fig. 1, in one embodiment, liquid collecting structure includes what is set around hemoglobin reaction tank outer wall Catch tray 103, catch tray 103 have the liquid collecting cavity 104 set around 10 outer wall of hemoglobin reaction tank, and liquid collecting cavity 104 enters Mouth is less than overflow port 102.When reaction tank drain does not block freely, reaction tank is full, extra liquid at overflow port 102 to Under flow out in liquid collecting cavity 104 and stored.Catch tray 103 can be integrally formed with hemoglobin reaction tank 10, can also be divided Body formula designs, and is sheathed on hemoglobin reaction tank 10.
Further, the liquid collecting cavity 104 of liquid collecting structure is equipped with liquid outlet 105, for liquid guide flow in liquid collecting cavity 104 to be arrived Assigned direction.When filling with liquid in liquid collecting cavity 104, it is necessary in time export liquid, liquid is along collection after avoiding liquid collecting cavity 104 full Liquid Pan103Bi flows out to 10 outer wall of reaction tank, pollutes outer wall, influences testing result.
More preferably 105 position of liquid outlet of liquid collecting cavity is disposed far from 10 outer wall of reaction tank and detection device One side exports liquid in catch tray 103.
In a kind of more preferably embodiment, please refer to Fig.1, it is oblique with angularly disposed water conservancy diversion at catch tray liquid outlet 105 Face 106, the water conservancy diversion inclined-plane 106 can be more advantageous to liquid in liquid collecting cavity and flow out to designated position.
In one embodiment, please referring to Fig.1, overflow port 102 is the opening for being arranged on 10 side wall of hemoglobin reaction tank, Overflow port 102 and 103 liquid outlet of liquid collecting structure, 1033 liquid flow outgoing direction are towards same direction.It can so reduce in overflow feelings Under condition, other side walls of reaction tank are contaminated.
Further, please continue to refer to Fig. 1, overflow port 102 is arranged on 10 side wall of reaction tank, by sample-adding 101 edge departments of opening Divide recessed formation.102 horizontal plane of overflow port of recessed formation is less than sample-adding 101 horizontal planes of opening, when 10 drain of reaction tank is not smooth When, liquid is flowed out to from overflow port 102 in liquid collecting structure 103, reduces sample-adding opening 101 to reaction tank 10 between liquid collecting structure Other side walls are contaminated.
It please refers to Fig.2, in another embodiment, when 10 drain of hemoglobin reaction tank is not smooth, reaction tank sample-adding is opened Mouthfuls 1011 can also be used as overflow port use, and surplus liquid is facilitated to be flow to from adding mouth in liquid collecting structure, then from liquid outlet position Export avoids liquid from polluting reaction tank outer wall along 10 outer wall flow detection device of reaction tank, and then influence testing result.
It please refers to Fig.3, in one embodiment, liquid collecting structure includes overflow pipe 107,107 one end of overflow pipe and overflow port Connection, the other end is by liquid guide flow to setting position.Tube chamber, that is, liquid collecting cavity of overflow pipe 107 flows for collecting at overflow port The liquid gone out, and it is guided to the position away from reaction tank outer wall and detection device.
In one embodiment, -5 are please referred to Fig.4, sampling needle 2, which is stretched into hemoglobin reaction tank, adds in sample, blood red egg The cavity wall 12 of white reaction chamber 11 includes the second wall surface 14 of the first wall surface 13 of the first wall surface 13 and connection.First wall surface 13 includes the One plane 131, the second plane 132, the first cambered surface 133 and the second cambered surface 134, the first plane 131 and the second plane 132 are opposite It sets, the first cambered surface 133 and the second cambered surface 134 are connected between the first plane 131 and the second plane 132 with being oppositely arranged.Please With continued reference to Fig. 6, the structure diagram of splitting of the reaction tank of hemoglobin reaction unit along axis 111, the second wall surface 14 includes Connect the first wall surface 13 first end 141 and away from the first wall surface 13 second end 142, the second wall surface 14 first end 141 to It is collapsed on the direction of second end 142.The reagent inlet 15 of connection reaction chamber 11 is additionally provided on reaction tank 10, reagent inlet 15 passes through Second wall surface 14, the first wall surface 13 or the junction of the second wall surface 14 and the first wall surface 14.
In the present embodiment, when reagent is from reagent inlet 15 into reaction chamber 11, reagent is in the cavity wall 12 of reaction chamber 11 Guiding is lower to form three-dimensional eddy flow.The reagent of eddy flow state can be mixed with the biological sample into reaction chamber well, The degree of mixing of reagent and biological sample is higher, and the reaction effect of reagent and biological sample is good, and sample analyser can pass through measurement Reagent reacts the formed accurate testing result of prepare liquid acquisition with biological sample.
It should be noted that reagent inlet 15 passes through the second wall surface 14 or the junction of the second wall surface 14 and the first wall surface 13 When, since the second wall surface 14 collapses on the direction of second end 142 in first end 141, reagent enters from the reagent inlet 15 After reaction chamber 11, reagent can directly impact the second wall surface 14 and form stereoscopic effect more preferably under the guiding of the second wall surface 14 Eddy flow.The present embodiment is based on the hemoglobin reaction tank that middle part is racetrack structure, and from reaction tank liquid level bottom, reagent inlet adds Reagent realizes good mixed effect with simple structure;And waste liquid port 16 is oppositely arranged with sample-adding opening 101, is arranged on Below 15 position of reaction tank reagent inlet, the discharge of waste liquid is more advantageous to after the completion of to be detected.
Embodiment two
In the present embodiment, a kind of sample analyser is provided.
The sample analyser includes sampling apparatus, device for storing liquid, any hemoglobin shown in above-described embodiment one Reaction unit and detection device, sampling apparatus are used for collection analysis sample, the sampling including sampling needle and driving sampling needle movement Pin driving portion, sampling needle driving portion driving sampling needle acquisition blood sample, and it is assigned to hemoglobin reaction unit;Device for storing liquid For storing one or more hemoglobin detection reagents, hemoglobin detection reagent is transported to hemoglobin by pipeline and reacts Device, pipeline connection device for storing liquid and hemoglobin reaction unit;Hemoglobin reaction unit is used for blood sample and blood red Protein assay reagent is reacted;Detection device is used to that the result after analysis sample and reagent reacting to be detected to obtain blood red Protein Detection result.
Each technical characteristic of embodiment described above can be combined arbitrarily, to make description succinct, not to above-mentioned reality It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited In contradiction, the scope that this specification is recorded all is considered to be.
Above example only expresses the several embodiments of the utility model, and description is more specific and detailed, but simultaneously Cannot the limitation to utility model scope therefore be interpreted as.It should be pointed out that come for those of ordinary skill in the art It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the utility model Protection domain.Therefore, the scope of protection of the utility model should be determined by the appended claims.

Claims (10)

1. a kind of hemoglobin reaction unit, which is characterized in that including:
Hemoglobin reaction tank, the hemoglobin reaction tank are provided with to house the reaction chamber of biological sample and reagent;With Waste liquid port in discharge waste liquid and reagent inlet for adding reagent, the waste liquid outlet and reagent inlet with it is described anti- Chamber is answered to connect;
The one end open of the reaction chamber is formed with the sample-adding opening entered suitable for sampling apparatus, is added in for biological sample The reaction chamber.
2. hemoglobin reaction unit according to claim 1, it is characterised in that:Further include liquid collecting structure;It is described blood red Albumen reaction tank includes the overflow port for being opened in setting height, and the overflow port is communicated with the reaction chamber, for the reaction It is overflowed when intracavity liquid is excessive;
The liquid collecting structure has liquid collecting cavity, and the liquid collecting cavity is communicated with the overflow port, overflows for storage or water conservancy diversion from described The liquid that head piece overflows.
3. hemoglobin reaction unit according to claim 2, it is characterised in that:The liquid collecting structure is included around described The catch tray that hemoglobin reaction tank outer wall is set, the catch tray have what is set around the hemoglobin reaction tank outer wall Liquid collecting cavity, the entrance of the liquid collecting cavity are less than the overflow port.
4. hemoglobin reaction unit according to claim 3, it is characterised in that:The liquid collecting cavity of the catch tray is equipped with out Liquid mouth, for by liquid guide flow to assigned direction.
5. hemoglobin reaction unit according to claim 4, it is characterised in that:The liquid outlet has angularly disposed Water conservancy diversion inclined-plane.
6. hemoglobin reaction unit according to claim 4, it is characterised in that:The overflow port is to be arranged on the blood The opening of Lactoferrin reaction tank side wall, the liquid flow outgoing direction of the overflow port and the liquid outlet is towards same direction.
7. hemoglobin reaction unit according to claim 2, it is characterised in that:The liquid collecting structure includes overflow pipe, Described overflow pipe one end is connected with the overflow port, and the other end is by liquid guide flow to setting position.
8. hemoglobin reaction unit according to claim 2, it is characterised in that:The edge concave of the sample-adding opening Into the overflow port.
9. hemoglobin reaction unit according to claim 1, it is characterised in that:
The cavity wall of the hemoglobin reaction chamber includes the first wall surface and connects the second wall surface of first wall surface, and described first Wall surface includes the first plane, the second plane, the first cambered surface and the second cambered surface, and first plane and second plane are opposite Set, first cambered surface and second cambered surface be connected to being oppositely arranged first plane and second plane it Between, second wall surface includes connecting the first end of first wall surface and the second end away from first wall surface, and described the Two wall surfaces are collapsed in the first end on the direction of the second end, and the reagent inlet is through second wall surface, described The junction of first wall surface or second wall surface and first wall surface.
10. a kind of sample analyser, it is characterised in that:Including sampling apparatus, device for storing liquid, such as any one of claim 1-9 institutes The hemoglobin reaction unit and detection device shown;
The sampling apparatus is used for collection analysis sample, including sampling needle and the sampling needle of the sampling needle movement is driven to drive Portion, the sampling needle driving portion drives the sampling needle acquisition blood sample, and is assigned to the hemoglobin reaction unit;
For the device for storing liquid for storing one or more hemoglobin detection reagents, the hemoglobin detection reagent passes through pipe Road is transported to the hemoglobin reaction unit, and the pipeline connects the device for storing liquid and the hemoglobin reaction unit;
The hemoglobin reaction unit is used to react the blood sample and the hemoglobin detection reagent;
The detection device is used to that the result after the analysis sample and reagent reacting to be detected to obtain hemoglobin detection As a result.
CN201721582883.7U 2017-11-23 2017-11-23 A kind of hemoglobin reaction unit and sample analyser Active CN207457252U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112654850A (en) * 2018-08-24 2021-04-13 深圳迈瑞生物医疗电子股份有限公司 Blood sample analyzer and blood sample mixing method
WO2023029056A1 (en) * 2021-09-06 2023-03-09 皮乐迪有限公司 Test tube
WO2023186095A1 (en) * 2022-03-31 2023-10-05 深圳迈瑞生物医疗电子股份有限公司 Biochemical analyzer

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112654850A (en) * 2018-08-24 2021-04-13 深圳迈瑞生物医疗电子股份有限公司 Blood sample analyzer and blood sample mixing method
WO2023029056A1 (en) * 2021-09-06 2023-03-09 皮乐迪有限公司 Test tube
WO2023186095A1 (en) * 2022-03-31 2023-10-05 深圳迈瑞生物医疗电子股份有限公司 Biochemical analyzer

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GR01 Patent grant
GR01 Patent grant
EE01 Entry into force of recordation of patent licensing contract
EE01 Entry into force of recordation of patent licensing contract

Assignee: Shenzhen Mindray Animal Medical Technology Co.,Ltd.

Assignor: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS Co.,Ltd.

Contract record no.: X2022440020009

Denomination of utility model: A hemoglobin reaction device and sample analyzer

Granted publication date: 20180605

License type: Common License

Record date: 20220804