CN109200097A - A kind of drug and preparation method thereof improving vaccine immunity uniformity - Google Patents
A kind of drug and preparation method thereof improving vaccine immunity uniformity Download PDFInfo
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- CN109200097A CN109200097A CN201811096041.XA CN201811096041A CN109200097A CN 109200097 A CN109200097 A CN 109200097A CN 201811096041 A CN201811096041 A CN 201811096041A CN 109200097 A CN109200097 A CN 109200097A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention is related to a kind of drug and preparation method thereof for improving vaccine immunity uniformity, in parts by weight, its raw material components is composed of the following components: 20~50 parts of honeysuckle, 50~80 parts of Radix Isatidis, 20~50 parts of radix scutellariae, 20~50 parts of Herba Epimedii, 50~80 parts of Fructus Forsythiae, in parts by weight, its raw material components is composed of the following components: 40 parts of honeysuckle, 60 parts of Radix Isatidis, 40 parts of radix scutellariae, 40 parts of Herba Epimedii, 60 parts of Fructus Forsythiae, the preparation method is that weighing above-mentioned Chinese medicine according to certain weight ratio, by pulverize and sieve different Chinese medicines are pulverized and mixed after use parts by weight for 10:1 ratio impregnate compatibility Chinese herbal medicine, heating decocts 60min, it stirs while hot, filtering；The dregs of a decoction add water decoction once, and water is not cross powder, and boiling time 30min filters to get product is arrived；Therefore, the present invention has the advantages that improve immune uniformity, enhances immune system, is clearing heat and detoxicating.
Description
Technical field
The invention belongs to the technical fields of aquaculture, and in particular to a kind of drug and its system for improving vaccine immunity uniformity
Preparation Method.
Background technique
Vaccine immunity in the prior art has a variety of causes to cause immuning failure and uniformity not high, makes immune effect not
It is good；For these problems, it is necessary to develop a kind of improve and uniformity, enhancing immune system, clearing heat and detoxicating raising vaccine is immunized
The drug and preparation method thereof of immune uniformity；Therefore, it develops a kind of improve and uniformity, enhancing immune system, heat-clearing solution is immunized
The drug and preparation method thereof of the raising vaccine immunity uniformity of poison has a very important significance.
Summary of the invention
The purpose of the invention is to overcome the deficiencies in the prior art, and provide a kind of improve and uniformity is immunized, enhances and exempts from
Epidemic disease system, clearing heat and detoxicating drug of raising vaccine immunity uniformity and preparation method thereof.
The object of the present invention is achieved like this: a kind of drug and preparation method thereof improving vaccine immunity uniformity is pressed
According to parts by weight meter, raw material components are composed of the following components: 20~50 parts of honeysuckle, 50~80 parts of Radix Isatidis, radix scutellariae 20~
50 parts, 20~50 parts of Herba Epimedii, 50~80 parts of Fructus Forsythiae.
In parts by weight, raw material components are composed of the following components: 40 parts of honeysuckle, 60 parts of Radix Isatidis, radix scutellariae 40
Part, 40 parts of Herba Epimedii, 60 parts of Fructus Forsythiae.
In parts by weight, raw material components are composed of the following components: 20 parts of honeysuckle, 50 parts of Radix Isatidis, radix scutellariae 20
Part, 20 parts of Herba Epimedii, 50 parts of Fructus Forsythiae.
In parts by weight, raw material components are composed of the following components: 50 parts of honeysuckle, 80 parts of Radix Isatidis, radix scutellariae 50
Part, 50 parts of Herba Epimedii, 80 parts of Fructus Forsythiae.
The preparation method is that above-mentioned Chinese medicine is weighed according to certain weight ratio, by pulverizing and sieving different traditional Chinese medicine powders
Parts by weight are used to impregnate the Chinese herbal medicine of compatibility for the ratio of 10:1 after broken mixing, heating decocts 60min, stirs, filters while hot；
The dregs of a decoction add water decoction once, and water is not cross powder, and boiling time 30min filters to get product is arrived.
Following elaboration is done below for the pharmacology of constituent:
Honeysuckle: nature and flavor and channel tropism: nature and flavor: honeysuckle is sweet in flavor, cold in nature.Channel tropism: return lung, the heart, stomach, large intestine channel.
Radix Isatidis: nature and flavor and channel tropism: nature and flavor: Radix Isatidis bitter, it is cold in nature.Channel tropism: return heart, stomach meridian.Effect: Radix Isatidis
There are clearing heat and detoxicating, cool blood, relieving sore-throat.
Radix scutellariae: nature and flavor and channel tropism: nature and flavor: radix scutellariae bitter, it is cold in nature.Channel tropism: return lung, gallbladder, stomach, large intestine channel.Heat-clearing and damp-drying drug.
Herba Epimedii: nature and flavor and channel tropism: nature and flavor: it is Herba Epimedii acrid flavour, sweet, it is warm-natured.Channel tropism: return liver and kidney channel.Herba Epimedii has
Tonifying kidney and strengthening yang, dispelling wind and eliminating dampness.
Fructus Forsythiae: nature and flavor and channel tropism: nature and flavor: Fructus Forsythiae bitter, cold nature.Channel tropism: return lung, the heart, gallbladder channel.It is clearing heat and detoxicating, dispelling wind
Heat dissipation.
Beneficial effects of the present invention: using honeysuckle as monarch drug in a prescription in the present invention, Flos lonicerae has clearing heat and detoxicating, evacuation wind
The effect of heat improves immunity, improves body performance；Using Radix Isatidis, radix scutellariae as ministerial drug, Radix Isatidis have it is clearing heat and detoxicating, it is cool
Blood, the effect of relieving sore-throat, radix scutellariae have the function of heat-clearing and damp-drying drug；Using Herba Epimedii as adjutant, Herba Epimedii has tonifying kidney and strengthening yang, wind-dispelling
The effect of dehumidifying improves immunity；It is to make medicine with Fructus Forsythiae, Fructus Forsythiae has the effect of clearing heat and detoxicating, wind-dispelling heat-dissipating；The above drug is mixed
Certain proportion is synthesized, the immune uniformity of raising, enhancing immune system, clearing heat and detoxicating medicine are prepared by certain production technology
Object.
Specific embodiment
Embodiment 1
A kind of drug and preparation method thereof improving vaccine immunity uniformity, in parts by weight, raw material components are by following
Group is grouped as: 20~50 parts of honeysuckle, 50~80 parts of Radix Isatidis, 20~50 parts of radix scutellariae, 20~50 parts of Herba Epimedii, Fructus Forsythiae 50~80
Part, in parts by weight, raw material components are composed of the following components: 40 parts of honeysuckle, 60 parts of Radix Isatidis, 40 parts of radix scutellariae, excessive
40 parts of the sheep leaves of pulse plants, 60 parts of Fructus Forsythiae, the preparation method is that weigh above-mentioned Chinese medicine according to certain weight ratio, by pulverize and sieve by
Different Chinese medicines use parts by weight to impregnate the Chinese herbal medicine of compatibility for the ratio of 10:1 after being pulverized and mixed, heat and decoct 60min, while hot
Stirring, filtering；The dregs of a decoction add water decoction once, and water is not cross powder, and boiling time 30min filters to get product is arrived.
Table 1
The result shows that: embodiment group is substantially reduced compared with the disease incidence of control group and antibiotic group, after taking drug of the invention, is mentioned
High disease resistance, improves immunity, and disease incidence is low.
Embodiment 2
A kind of drug and preparation method thereof improving vaccine immunity uniformity, in parts by weight, raw material components are by following
Group is grouped as: 20~50 parts of honeysuckle, 50~80 parts of Radix Isatidis, 20~50 parts of radix scutellariae, 20~50 parts of Herba Epimedii, Fructus Forsythiae 50~80
Part, in parts by weight, raw material components are composed of the following components: 20 parts of honeysuckle, 50 parts of Radix Isatidis, 20 parts of radix scutellariae, excessive
20 parts of the sheep leaves of pulse plants, 50 parts of Fructus Forsythiae, in parts by weight, raw material components are composed of the following components: 50 parts of honeysuckle, Radix Isatidis 80
Part, 50 parts of radix scutellariae, 50 parts of Herba Epimedii, 80 parts of Fructus Forsythiae, the preparation method is that above-mentioned Chinese medicine is weighed according to certain weight ratio,
By pulverize and sieve different Chinese medicines are pulverized and mixed after use parts by weight for 10:1 ratio impregnate compatibility Chinese herbal medicine, heating
60min is decocted, stirs, filter while hot；The dregs of a decoction add water decoction once, and water is not cross powder, boiling time 30min, filtering,
Getting the product.
Using honeysuckle as monarch drug in a prescription in the present invention；Using Radix Isatidis, radix scutellariae as ministerial drug；Using Herba Epimedii as adjutant；It is to make with Fructus Forsythiae
Medicine；The above drug mixing is proportional, is prepared into the immune uniformity of raising, enhancing siberian crabapple by certain production technology
System, clearing heat and detoxicating drug.
Specific embodiment is to further explanation of the invention rather than limits, and is existed for those of ordinary skills
Further transformation is done to structure in the case where not departing from substantive content of the present invention, and all these transformation all should belong to institute of the present invention
Attached scope of protection of the claims.
Claims (5)
1. a kind of drug and preparation method thereof for improving vaccine immunity uniformity, it is characterised in that: in parts by weight, former
Expect that component is composed of the following components: 20~50 parts of honeysuckle, 50~80 parts of Radix Isatidis, 20~50 parts of radix scutellariae, Herba Epimedii 20~50
Part, 50~80 parts of Fructus Forsythiae.
2. a kind of drug and preparation method thereof for improving vaccine immunity uniformity according to claim 1, it is characterised in that:
In parts by weight, raw material components are composed of the following components: 40 parts of honeysuckle, 60 parts of Radix Isatidis, 40 parts of radix scutellariae, Herba Epimedii
40 parts, 60 parts of Fructus Forsythiae.
3. a kind of drug and preparation method thereof for improving vaccine immunity uniformity according to claim 1, it is characterised in that:
In parts by weight, raw material components are composed of the following components: 20 parts of honeysuckle, 50 parts of Radix Isatidis, 20 parts of radix scutellariae, Herba Epimedii
20 parts, 50 parts of Fructus Forsythiae.
4. a kind of drug and preparation method thereof for improving vaccine immunity uniformity according to claim 1, it is characterised in that:
In parts by weight, raw material components are composed of the following components: 50 parts of honeysuckle, 80 parts of Radix Isatidis, 50 parts of radix scutellariae, Herba Epimedii
50 parts, 80 parts of Fructus Forsythiae.
5. a kind of drug and preparation method thereof for improving vaccine immunity uniformity according to claim 1, it is characterised in that:
The preparation method is that weigh above-mentioned Chinese medicine according to certain weight ratio, by after pulverizing and sieving and being pulverized and mixed different Chinese medicines
Parts by weight are used to impregnate the Chinese herbal medicine of compatibility for the ratio of 10:1, heating decocts 60min, stirs, filters while hot；The dregs of a decoction add again
Water decocts once, and water is not cross powder, and boiling time 30min filters to get product is arrived.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811096041.XA CN109200097A (en) | 2018-09-19 | 2018-09-19 | A kind of drug and preparation method thereof improving vaccine immunity uniformity |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811096041.XA CN109200097A (en) | 2018-09-19 | 2018-09-19 | A kind of drug and preparation method thereof improving vaccine immunity uniformity |
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| CN201811096041.XA Pending CN109200097A (en) | 2018-09-19 | 2018-09-19 | A kind of drug and preparation method thereof improving vaccine immunity uniformity |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108853221A (en) * | 2018-09-19 | 2018-11-23 | 洛阳汉德生物科技有限公司 | A kind of drug and preparation method thereof for preventing and treating newcastle disease |
| CN108904700A (en) * | 2018-09-19 | 2018-11-30 | 洛阳汉德生物科技有限公司 | A kind of drug and preparation method thereof for preventing and treating blue otopathy |
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| CN1958008A (en) * | 2005-10-31 | 2007-05-09 | 天津市润拓生物技术有限公司 | Animal use compound medicament with effects of removing toxic heat, and preparation method |
| CN104706825A (en) * | 2013-12-11 | 2015-06-17 | 天津嘉创生物科技有限公司 | Traditional Chinese medicine oral liquid with antiviral function and preparation method thereof |
| CN106138226A (en) * | 2016-09-08 | 2016-11-23 | 河南弘羊生物科技有限公司 | A kind of Chinese medicine granules preventing and treating porcine hyperthermia and preparation method thereof |
| CN108853221A (en) * | 2018-09-19 | 2018-11-23 | 洛阳汉德生物科技有限公司 | A kind of drug and preparation method thereof for preventing and treating newcastle disease |
| CN108904700A (en) * | 2018-09-19 | 2018-11-30 | 洛阳汉德生物科技有限公司 | A kind of drug and preparation method thereof for preventing and treating blue otopathy |
-
2018
- 2018-09-19 CN CN201811096041.XA patent/CN109200097A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1958008A (en) * | 2005-10-31 | 2007-05-09 | 天津市润拓生物技术有限公司 | Animal use compound medicament with effects of removing toxic heat, and preparation method |
| CN104706825A (en) * | 2013-12-11 | 2015-06-17 | 天津嘉创生物科技有限公司 | Traditional Chinese medicine oral liquid with antiviral function and preparation method thereof |
| CN106138226A (en) * | 2016-09-08 | 2016-11-23 | 河南弘羊生物科技有限公司 | A kind of Chinese medicine granules preventing and treating porcine hyperthermia and preparation method thereof |
| CN108853221A (en) * | 2018-09-19 | 2018-11-23 | 洛阳汉德生物科技有限公司 | A kind of drug and preparation method thereof for preventing and treating newcastle disease |
| CN108904700A (en) * | 2018-09-19 | 2018-11-30 | 洛阳汉德生物科技有限公司 | A kind of drug and preparation method thereof for preventing and treating blue otopathy |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108853221A (en) * | 2018-09-19 | 2018-11-23 | 洛阳汉德生物科技有限公司 | A kind of drug and preparation method thereof for preventing and treating newcastle disease |
| CN108904700A (en) * | 2018-09-19 | 2018-11-30 | 洛阳汉德生物科技有限公司 | A kind of drug and preparation method thereof for preventing and treating blue otopathy |
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Application publication date: 20190115 |