CN109182117A - Nucleic acid amplification detection device and diagnositc analyser - Google Patents
Nucleic acid amplification detection device and diagnositc analyser Download PDFInfo
- Publication number
- CN109182117A CN109182117A CN201811093880.6A CN201811093880A CN109182117A CN 109182117 A CN109182117 A CN 109182117A CN 201811093880 A CN201811093880 A CN 201811093880A CN 109182117 A CN109182117 A CN 109182117A
- Authority
- CN
- China
- Prior art keywords
- detection device
- nucleic acid
- acid amplification
- pulldown
- microcosmic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
Abstract
The present invention relates to analysis and testing equipment fields, in particular to a kind of nucleic acid amplification detection device and diagnositc analyser.The device includes microcosmic chip, detection device and movement component.Detection device includes heat circulating system and live signal detection system, and heat circulating system is used to carry out nucleic acid amplification for the sample in microcosmic chip to provide suitable temperature；Live signal detection system is used to carry out fluorescence detection to the sample after generation nucleic acid amplification.Movement component is used to grab microcosmic chip and microcosmic chip is transferred to the detection zone of detection device.The device is easy to operate, can carry out nucleic acid amplification and fluorescence detection simultaneously, greatly facilitates the detection for needing the sample for PCR processing.Microcosmic chip is transferred to detection device by movement component to be expanded, detect, the nucleic acid amplification detection device high degree of automation, is conducive to improve detection efficiency.
Description
Technical field
The present invention relates to analysis and testing equipment fields, in particular to a kind of nucleic acid amplification detection device and diagnosis
Analyzer.
Background technique
Medical diagnosis industry is the key factor on health care today basis.However it currently, is examined in vitro regardless of route
Oneself warp of disconnected analysis becomes the bottleneck of patient care.In this regard, there are several reasons.Firstly, many diagnostic analysis only use height professional
Equipment carry out, be expensive and can only be operated by trained clinician.This equipment is only found in some positions
Only one in one frequent what given urban area in office.It is used this means that most of hospitals need for sample to be sent to these places
In analysis, therefore freight and transport delay are generated, and be possibly even sample loss or mishandling.Second, institute
The equipment of discussion is not generally obtainable when needed, is run with batch, thus for many sample delays processing when
Between, because they have to wait for machine to be full of before they can run.
It understands sample flow and resolves into several committed steps, it is desirable to the mode of automation.For example, once from trouble
Person extracts, and biological sample must be suitable for placing using the form of PCR processing scheme, to expand purpose carrier.Preparation is used for PCR
Sample be currently to spend the time and the step of labour intensive, although nobody needs special skills.But the extraction of automation
Detection device is more and more by demand.
Summary of the invention
The purpose of the present invention is to provide a kind of nucleic acid amplification detection devices, solve the existing sample for PCR processing
Detect inconvenient problem.
Another object of the present invention is to provide a kind of diagnositc analyser, which can be used in PCR processing
Sample detection, it is easy to operate.
To achieve the goals above, technical solution used in the embodiment of the present invention is as follows:
A kind of nucleic acid amplification detection device, comprising: microcosmic chip, microcosmic chip is for accommodating multiple samples to be detected；
Detection device, detection device include heat circulating system and live signal detection system, and heat circulating system is used for as in microcosmic chip
Sample carry out nucleic acid amplification suitable temperature be provided；Live signal detection system be used for occur nucleic acid amplification after sample into
Row fluorescence detection；And movement component, movement component is for grabbing microcosmic chip and microcosmic chip being transferred to detection device
Detection zone.
In preferred embodiments of the present invention, multiple channels are provided on microcosmic chip, each channel is used to accommodate
One sample.
In preferred embodiments of the present invention, it is provided with mouth of sealing with wax in microcosmic chip, when microcosmic chip is placed in detection device
When being heated, a mouthful automatic sealing of sealing with wax.
In preferred embodiments of the present invention, movement component includes manipulator for grabbing microcosmic chip and for will
Microcosmic chip is transferred to the rotating arm of detection zone；Rotating arm is connected to manipulator.
In preferred embodiments of the present invention, manipulator includes mounting plate, the first pulldown and the second pulldown；First pulldown and
The opposite two sides of mounting plate are arranged in second pulldown, and the first pulldown and the second pulldown being capable of or phases close to each other with respect to mounting plate
It is mutually separate, to firmly grasp or unclamp microcosmic chip.
The first driving mechanism is provided in preferred embodiments of the present invention, on mounting plate, the transmission of the first driving mechanism connects
It is connected to the first pulldown and the second pulldown, the first driving mechanism is configurable for the first pulldown of driving and the opposite fortune of the second pulldown
It is dynamic.
In preferred embodiments of the present invention, rotating arm includes the first arm body and the second arm body；First arm body has first
End and opposite second end；Second arm body is mounted on first end by lifting assembly, and the second arm body can be with respect on the first arm body
Lower elevating movement；Second end is provided with the second driving mechanism for driving the first arm body to rotate.
In preferred embodiments of the present invention, it is provided with third driving mechanism on the second arm body, robotic transfer is connected to
Third driving mechanism；Third driving mechanism is configurable for driving manipulator rotation.
In preferred embodiments of the present invention, heat circulating system includes heating component and radiating subassembly；Heating component and dissipate
Hot component is arranged at the lower section of detection zone；Live signal detection system includes optical emission system and fluorescence detector.
A kind of diagnositc analyser, the diagnositc analyser include such as above-mentioned nucleic acid amplification detection device.
The beneficial effects of the present invention are:
A kind of nucleic acid amplification detection device provided by the invention, including microcosmic chip, detection device and movement component.Its
In, microcosmic chip is for accommodating multiple samples to be detected.Detection device includes heat circulating system and live signal detection system,
Heat circulating system is used to carry out nucleic acid amplification for the sample in microcosmic chip to provide suitable temperature；Live signal detection system is used
In to the sample progress fluorescence detection after nucleic acid amplification occurs.Movement component is for grabbing microcosmic chip and shifting microcosmic chip
To the detection zone of detection device.The device is easy to operate, can carry out nucleic acid amplification and fluorescence detection simultaneously, greatly facilitate
Need the detection of the sample for PCR processing.Microcosmic chip detection device is transferred to by movement component to be expanded, examine
It surveys, the nucleic acid amplification detection device high degree of automation, is conducive to improve detection efficiency.
A kind of diagnositc analyser provided by the invention, the diagnositc analyser include such as above-mentioned nucleic acid amplification detection device.
The diagnositc analyser greatly facilitates the sample needed for PCR processing by the way that above-mentioned nucleic acid amplification detection device is arranged
Detection.
Detailed description of the invention
In order to illustrate the technical solution of the embodiments of the present invention more clearly, below will be to needed in the embodiment attached
Figure is briefly described, it should be understood that the following drawings illustrates only certain embodiments of the present invention, therefore is not construed as pair
The restriction of range for those of ordinary skill in the art without creative efforts, can also be according to this
A little attached drawings obtain other relevant attached drawings.
Fig. 1 is the structural schematic diagram for the nucleic acid amplification detection device that first embodiment of the invention provides；
Fig. 2 is the structural schematic diagram of the microcosmic chip for the nucleic acid amplification detection device that first embodiment of the invention provides；
Fig. 3 is the structure at the first visual angle of the movement component for the nucleic acid amplification detection device that first embodiment of the invention provides
Schematic diagram；
Fig. 4 is the structure at the second visual angle of the movement component for the nucleic acid amplification detection device that second embodiment of the invention provides
Schematic diagram；
Fig. 5 is the structural schematic diagram of the manipulator for the nucleic acid amplification detection device that second embodiment of the invention provides.
Icon: 10- nucleic acid amplification detection device；The microcosmic chip of 100-；The channel 110-；120- seals with wax mouth；130- well；
200- detection device；210- heat circulating system；220- live signal detection system；230- detection zone；300- movement component；
310- manipulator；311- mounting plate；The first pulldown of 312-；The second pulldown of 313-；320- rotating arm；330- the first arm body；331-
First end；332- second end；340- the second arm body；341- lifting assembly；343- linear guide；The second driving mechanism of 350-；
The second motor of 351-；352- the second V belt translation component；360- third driving mechanism；361- third motor；362- third V belt translation
Component；The first driving mechanism of 370-.
Specific embodiment
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention
In attached drawing, technical scheme in the embodiment of the invention is clearly and completely described, it is clear that described embodiment is
A part of the embodiment of the present invention, instead of all the embodiments.The present invention being usually described and illustrated herein in the accompanying drawings is implemented
The component of example can be arranged and be designed with a variety of different configurations.
Therefore, the detailed description of the embodiment of the present invention provided in the accompanying drawings is not intended to limit below claimed
The scope of the present invention, but be merely representative of selected embodiment of the invention.Based on the embodiments of the present invention, this field is common
Technical staff's every other embodiment obtained without creative efforts belongs to the model that the present invention protects
It encloses.
It should also be noted that similar label and letter indicate similar terms in following attached drawing, therefore, once a certain Xiang Yi
It is defined in a attached drawing, does not then need that it is further defined and explained in subsequent attached drawing.
In the description of the embodiment of the present invention, it should be noted that the orientation of the instructions such as term " on ", "inner" or position are closed
System for be based on the orientation or positional relationship shown in the drawings or the invention product using when the orientation usually put or position close
System, is merely for convenience of description of the present invention and simplification of the description, rather than the device or element of indication or suggestion meaning must have
Specific orientation is constructed and operated in a specific orientation, therefore is not considered as limiting the invention.
In the description of the present invention, it is also necessary to which explanation is unless specifically defined or limited otherwise, term " setting ",
" installation ", " connected ", " connection " shall be understood in a broad sense, for example, it may be fixedly connected, may be a detachable connection or one
Connect to body；It can be directly connected, the connection inside two elements can also be can be indirectly connected through an intermediary.
For the ordinary skill in the art, the concrete meaning of above-mentioned term in the present invention can be understood with concrete condition.
First embodiment
Fig. 1-Fig. 5 is please referred to, the present embodiment provides a kind of nucleic acid amplification detection devices 10 comprising microcosmic chip 100, inspection
Survey device 200 and movement component 300.For microcosmic chip 100 for accommodating multiple samples to be detected, movement component 300 can
Microcosmic chip 100 is pipetted to being expanded in detection device 200, being detected, needs to handle for PCR to greatly facilitate
Sample detection.Microcosmic chip 100 detection device 200 is transferred to by movement component 300 to be expanded, detect, the core
Sour 10 high degree of automation of augmentation detection device is conducive to improve detection efficiency.
Further, multiple channels 110 are provided on microcosmic chip 100, each channel 110 is used to one sample of accommodating
This, is detected.
Further, in this embodiment nucleic acid amplification detection device 10 includes multiple microcosmic chips 100.Multiple microcosmic cores
Piece 100 is stacked together, and continuously pipettes, detects so as to realize, improves the detection of entire nucleic acid amplification detection device 10
Efficiency.
Further, due to being provided with multiple channels 110 on each microcosmic chip 100, to can be achieved at the same time more
It is detected while a sample.The detection mode of this multichannel 110 further increases entire nucleic acid amplification detection device 10
Detection efficiency.
Specifically, in the present embodiment, 48 channels 110 are provided on the microcosmic chip 100 of each above-mentioned, so as to
It realizes and is detected while 48 samples simultaneously.
It should be understood that in other optional embodiments of the invention, it can also basis on the microcosmic chip 100 of each above-mentioned
The actual channel 110 for needing to select setting other quantity.
Further, well 130 is provided in microcosmic chip 100 and mouth 120 of sealing with wax.Sample is added from well 130
Afterwards, microcosmic chip 100 is made.When microcosmic chip 100, which is placed in detection device 200, to be heated, 120 automatic sealing of mouth of sealing with wax.
By the way that mouth 120 of sealing with wax is arranged in above-mentioned microcosmic chip 100, the safety of sample further ensure that.It answers
Understand, the performance of wax itself is utilized in the above-mentioned self-sealing principle of mouth 120 of sealing with wax, be it is well-known to those skilled in the art,
Details are not described herein again.
In other optional embodiments of the invention, the sealing of above-mentioned microcosmic chip 100 also be can choose using ability
Other sealing modes applicatory of domain.
Further, movement component 300 is used to realize crawl and movement to microcosmic chip 100.To greatly improve
The degree of automation of entire nucleic acid amplification detection device 10, is conducive to further improve entire nucleic acid amplification detection device 10
Detection efficiency.
Further, movement component 300 includes manipulator 310 for grabbing microcosmic chip 100 and for will be microcosmic
Chip 100 is transferred to the rotating arm 320 of detection zone.
Further, rotating arm 320 is connected to manipulator 310.Rotating arm 320 can rotate in a certain range, from
And drive manipulator 310 to rotate, and then manipulator 310 is turned in detection device 200, microcosmic chip 100 is placed on inspection
It surveys at the detection zone 230 of device 200.
Further, rotating arm 320 includes the first arm body 330 and the second arm body 340.
Further, the first arm body 330 has first end 331 and opposite second end 332.It is provided at second end 332
The second driving mechanism 350 for driving the first arm body 330 to rotate.
Specifically, in the present embodiment, the second driving mechanism 350 includes the second motor 351 and the second V belt translation component
352.The transmission connection of second motor 351 is sequentially connected in the second V belt translation component 352, the second V belt translation component 352 in the first arm
The second end 332 of body 330.To when the rotation of the second motor 351, can turn drives second tape transmission component 352 move, and then band
Entire first arm body 330 is moved to rotate.
Further, the second arm body 340 is mounted on first end 331 by lifting assembly 341, and the second arm body 340 being capable of phase
To the 330 oscilaltion campaign of the first arm body.
Specifically, in the present embodiment, lifting assembly 341 is spindle motor component.Linear guide 343 is arranged in the second arm
On body 340, spindle motor component is sequentially connected in linear guide 343.When spindle motor Component driver, entire second arm is driven
Body 340 moves up and down along linear guide 343, to conveniently pipette the microcosmic chip 100 stacked.
Further, third driving mechanism 360 is provided on the second arm body 340, the transmission connection of manipulator 310 is driven in third
Motivation structure 360.Third driving mechanism 360 is configurable for the rotation of driving manipulator 310.And then when manipulator 310 clamp it is micro-
When seeing chip 100, microcosmic chip 100 can be rotated together with manipulator 310, and more convenient manipulator 310 is by microcosmic chip
100 clampings are placed in detection device 200.
Specifically, in the present embodiment, third driving mechanism 360 includes third motor 361 and third V belt translation component
362.Third motor 361 is sequentially connected in third V belt translation component 362, and manipulator 310 is connected to third V belt translation component 362,
To which when third motor 361 rotates, driving third V belt translation component 362 is moved, and then manipulator 310 is driven to rotate.Specifically
Ground can grab microcosmic chip 100 when manipulator 310 clamps microcosmic chip 100 more flexiblely.
Further, manipulator 310 includes mounting plate 311, the first pulldown 312 and the second pulldown 313.
Further, the opposite two sides of mounting plate 311, the first pulldown is arranged in the first pulldown 312 and the second pulldown 313
312 and second pulldown 313 close to each other with respect to mounting plate 311 can perhaps be located remotely from each other promptly or to unclamp microcosmic chip
100。
Specifically, the first driving mechanism 370 is additionally provided on mounting plate 311, the first driving mechanism 370 is sequentially connected in peace
Loading board 311, the first driving mechanism 370 are configurable for the rotation of drive installation plate 311.
In the present embodiment, the first driving mechanism 370 is stepper motor.First driving mechanism 370 is sequentially connected in first
Pulldown 312 and the second pulldown 313.To drive the first pulldown 312 and the second pulldown 313 when the rotation of the first driving mechanism 370
Relative motion, so that the first pulldown 312 and the second pulldown 313 is close to each other is perhaps located remotely from each other and then promptly or pine
Open microcosmic chip 100.
Further, detection device 200 includes heat circulating system 210 and live signal detection system 220, heat circulating system
210 provide suitable temperature for carrying out nucleic acid amplification for the sample in microcosmic chip 100.Live signal detection system 220 is used
In to the sample progress fluorescence detection after nucleic acid amplification occurs.
Further, heat circulating system 210 includes heating component and radiating subassembly；Heating component and radiating subassembly are respectively provided with
In the lower section of detection zone.
Specifically, in the present embodiment, heating component is six chip semiconductor heating devices.Radiating subassembly include radiator,
Radiator fan etc., for realizing the temperature requirements in amplification procedure.
Above-mentioned heating device, radiator, radiator fan are common part in the prior art, and details are not described herein again.
Further, live signal detection system 220 includes optical emission system and fluorescence detector.
Specifically, in the present embodiment, including the extraordinary halogen tungsten lamp light source for generating exciting light, the optical filtering of 5 kinds of colors
Piece, a high sensitivity detector for the specialty optical fiber of conducted emission light beam and for receiving sample fluorescence signal.
What above-mentioned optical emission system and fluorescence detector were also well known to the skilled person, it is no longer superfluous herein
It states.
Second embodiment
The present embodiment provides a kind of diagnositc analyser, which includes such as above-mentioned nucleic acid amplification detection device.
The diagnositc analyser greatly facilitates the sample needed for PCR processing by the way that above-mentioned nucleic acid amplification detection device is arranged
Detection.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, for the skill of this field
For art personnel, the invention may be variously modified and varied.All within the spirits and principles of the present invention, made any to repair
Change, equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.It should also be noted that similar label and letter exist
Similar terms are indicated in following attached drawing, therefore, once being defined in a certain Xiang Yi attached drawing, are then not required in subsequent attached drawing
It is further defined and explained.
Claims (10)
1. a kind of nucleic acid amplification detection device characterized by comprising
Microcosmic chip, the microcosmic chip is for accommodating multiple samples to be detected；
Detection device, the detection device include heat circulating system and live signal detection system, and the heat circulating system is used for
Nucleic acid amplification is carried out for the sample in the microcosmic chip, and suitable temperature is provided；The live signal detection system is used for
Fluorescence detection is carried out to the sample after generation nucleic acid amplification；And
Movement component, the movement component are filled for grabbing the microcosmic chip and the microcosmic chip being transferred to the detection
The detection zone set.
2. nucleic acid amplification detection device as described in claim 1, which is characterized in that
Multiple channels are provided on the microcosmic chip, each described channel is used to one sample of accommodating.
3. nucleic acid amplification detection device as claimed in claim 2, which is characterized in that
It is provided with mouth of sealing with wax in the microcosmic chip, it is described when the microcosmic chip, which is placed in the detection device, to be heated
It seals with wax a mouthful automatic sealing.
4. nucleic acid amplification detection device as described in claim 1, which is characterized in that
The movement component includes manipulator for grabbing microcosmic chip and described for the microcosmic chip to be transferred to
The rotating arm of detection zone；
The rotating arm is connected to the manipulator.
5. nucleic acid amplification detection device as claimed in claim 4, which is characterized in that
The manipulator includes mounting plate, the first pulldown and the second pulldown；
The opposite two sides of the mounting plate, first pulldown and described is arranged in first pulldown and second pulldown
Two pulldowns can the relatively described mounting plate be close to each other is perhaps located remotely from each other promptly or to unclamp the microcosmic chip.
6. nucleic acid amplification detection device as claimed in claim 5, which is characterized in that
The first driving mechanism is provided on the mounting plate, the first driving mechanism transmission connection is in first pulldown and institute
The second pulldown is stated, first driving mechanism is configurable for driving first pulldown and the opposite fortune of second pulldown
It is dynamic.
7. nucleic acid amplification detection device as claimed in claim 5, which is characterized in that
The rotating arm includes the first arm body and the second arm body；
The first arm body has first end and opposite second end；The second arm body is mounted on described by lifting assembly
One end, the second arm body being capable of the relatively described first arm body oscilaltion campaigns；
The second end is provided with the second driving mechanism for driving the first arm body rotation.
8. nucleic acid amplification detection device as claimed in claim 7, which is characterized in that
Third driving mechanism is provided on the second arm body, the robotic transfer is connected to the third driving mechanism；
The third driving mechanism is configurable for that the manipulator is driven to rotate.
9. nucleic acid amplification detection device as described in claim 1, which is characterized in that
The heat circulating system includes heating component and radiating subassembly；The heating component and radiating subassembly are arranged at the inspection
Survey the lower section in area；
The live signal detection system includes optical emission system and fluorescence detector.
10. a kind of diagnositc analyser, which is characterized in that the diagnositc analyser includes as claim 1-9 is described in any item
Nucleic acid amplification detection device.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811093880.6A CN109182117A (en) | 2018-09-19 | 2018-09-19 | Nucleic acid amplification detection device and diagnositc analyser |
| PCT/CN2019/091417 WO2020057192A1 (en) | 2018-09-19 | 2019-06-14 | Nucleic acid amplification detection device and diagnostic analyzer |
| DE212019000102.5U DE212019000102U1 (en) | 2018-09-19 | 2019-06-14 | Nucleic acid amplification detection device and diagnostic analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811093880.6A CN109182117A (en) | 2018-09-19 | 2018-09-19 | Nucleic acid amplification detection device and diagnositc analyser |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109182117A true CN109182117A (en) | 2019-01-11 |
Family
ID=64908404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811093880.6A Pending CN109182117A (en) | 2018-09-19 | 2018-09-19 | Nucleic acid amplification detection device and diagnositc analyser |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN109182117A (en) |
| WO (1) | WO2020057192A1 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020057192A1 (en) * | 2018-09-19 | 2020-03-26 | 基蛋生物科技股份有限公司 | Nucleic acid amplification detection device and diagnostic analyzer |
| CN111426661A (en) * | 2020-04-09 | 2020-07-17 | 基蛋生物科技股份有限公司 | Fluorescence data acquisition and discrimination method in nucleic acid amplification stage |
| CN112940920A (en) * | 2021-01-31 | 2021-06-11 | 新羿制造科技（北京）有限公司 | Biochip analyzer |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117384751B (en) * | 2023-12-12 | 2024-04-02 | 杭州杰毅生物技术有限公司 | Detection integrated machine and detection method thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103552075A (en) * | 2013-09-29 | 2014-02-05 | 爱马特（江苏）自动化有限公司 | Structure of workpiece transfer manipulator device with lifting rotary arms |
| CN103597358A (en) * | 2011-04-15 | 2014-02-19 | 贝克顿·迪金森公司 | Scanning real-time microfluidic thermo-cycler and methods for synchronized thermocycling and scanning optical detection |
| CN204269665U (en) * | 2014-12-22 | 2015-04-15 | 四川迈克生物医疗电子有限公司 | Full-automatic sample analyser |
| CN205497495U (en) * | 2016-03-22 | 2016-08-24 | 江苏豪林自动化科技有限公司 | Revolve rotating arm type pile up neatly machinery hand |
| CN106140338A (en) * | 2016-06-21 | 2016-11-23 | 中国科学院电子学研究所 | Micro-fluidic chip system and apply the method that this system carries out isothermal duplication and detection |
| CN106701566A (en) * | 2016-12-22 | 2017-05-24 | 山东艾克韦生物技术有限公司 | Nucleic acid extraction, amplification and detection integrated mechanical device |
| CN106916743A (en) * | 2017-03-19 | 2017-07-04 | 北京化工大学 | Integrated nucleic acid extraction and augmentation detection system |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015188377A (en) * | 2014-03-28 | 2015-11-02 | セイコーエプソン株式会社 | Cartridge for nucleic acid amplification reaction and nucleic acid amplification device |
| CN205138989U (en) * | 2015-08-03 | 2016-04-06 | 基蛋生物科技股份有限公司 | Biochemical immunity mixes analytical equipment |
| CN107904156B (en) * | 2017-10-31 | 2021-06-29 | 领航基因科技（杭州）有限公司 | Integrated full-automatic digital PCR detection system and implementation method |
| CN109182117A (en) * | 2018-09-19 | 2019-01-11 | 基蛋生物科技股份有限公司 | Nucleic acid amplification detection device and diagnositc analyser |
-
2018
- 2018-09-19 CN CN201811093880.6A patent/CN109182117A/en active Pending
-
2019
- 2019-06-14 WO PCT/CN2019/091417 patent/WO2020057192A1/en active Application Filing
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103597358A (en) * | 2011-04-15 | 2014-02-19 | 贝克顿·迪金森公司 | Scanning real-time microfluidic thermo-cycler and methods for synchronized thermocycling and scanning optical detection |
| CN103552075A (en) * | 2013-09-29 | 2014-02-05 | 爱马特（江苏）自动化有限公司 | Structure of workpiece transfer manipulator device with lifting rotary arms |
| CN204269665U (en) * | 2014-12-22 | 2015-04-15 | 四川迈克生物医疗电子有限公司 | Full-automatic sample analyser |
| CN205497495U (en) * | 2016-03-22 | 2016-08-24 | 江苏豪林自动化科技有限公司 | Revolve rotating arm type pile up neatly machinery hand |
| CN106140338A (en) * | 2016-06-21 | 2016-11-23 | 中国科学院电子学研究所 | Micro-fluidic chip system and apply the method that this system carries out isothermal duplication and detection |
| CN106701566A (en) * | 2016-12-22 | 2017-05-24 | 山东艾克韦生物技术有限公司 | Nucleic acid extraction, amplification and detection integrated mechanical device |
| CN106916743A (en) * | 2017-03-19 | 2017-07-04 | 北京化工大学 | Integrated nucleic acid extraction and augmentation detection system |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020057192A1 (en) * | 2018-09-19 | 2020-03-26 | 基蛋生物科技股份有限公司 | Nucleic acid amplification detection device and diagnostic analyzer |
| CN111426661A (en) * | 2020-04-09 | 2020-07-17 | 基蛋生物科技股份有限公司 | Fluorescence data acquisition and discrimination method in nucleic acid amplification stage |
| CN111426661B (en) * | 2020-04-09 | 2022-10-18 | 基蛋生物科技股份有限公司 | Fluorescence data acquisition and discrimination method in nucleic acid amplification stage |
| CN112940920A (en) * | 2021-01-31 | 2021-06-11 | 新羿制造科技（北京）有限公司 | Biochip analyzer |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020057192A1 (en) | 2020-03-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109182117A (en) | Nucleic acid amplification detection device and diagnositc analyser | |
| CN109061210B (en) | Full-automatic luminous chemical immunity analyzer | |
| ES2594333T3 (en) | Automated system to isolate, amplify and detect a white nucleic acid sequence | |
| JP6850340B2 (en) | Conducting antimicrobial susceptibility testing and related systems and methods | |
| US20190204233A1 (en) | Chemiluminescence Detector and Detection Method Thereof | |
| CN103042531B (en) | For grasping and keep the device of diagnosis box | |
| CN104777321B (en) | Chemiluminescence immune assay device | |
| JP4637166B2 (en) | Sample-transport module for a multi-instrument clinical work cell | |
| US8747745B2 (en) | Apparatus and method for biochemical analysis | |
| CN107290562B (en) | A kind of automatic sample handling system for the detection of sample cell high throughput | |
| WO2011087218A2 (en) | Apparatus for analyzing sample | |
| JPH07191042A (en) | Automatic diagnostic device for analyzing specimen in test pack for material to be analyzed | |
| BRPI0413793B1 (en) | Apparatus for processing a fluid sample, use of an apparatus, method for processing a fluid sample, use of a method, and use of a binder material in a method | |
| CN108865659A (en) | Nucleic acid extraction and amplification fluorescent detection system | |
| BR112014005007B1 (en) | MICROSCOPE SLIDE CARRYING CASSETTE | |
| CN104297498A (en) | Fully automatic biochemical and luminescent immunoassay system | |
| CN109580596B (en) | Chemiluminescent detector, incubation device and incubation method thereof | |
| CN206920455U (en) | A kind of blood coagulation analyzer and its test panel device | |
| WO2021068911A1 (en) | Rotating disc type multiple measurement device and system | |
| CN111534575A (en) | Microfluidic nucleic acid detection card box and kit | |
| CN105441321B (en) | Fully automatic integral nucleic acids instrument | |
| CN208883861U (en) | Nucleic acid extraction and amplification fluorescent detection system | |
| CN115772466A (en) | Molecular detection all-in-one machine equipment | |
| WO2021120759A1 (en) | Fully-automated chemiluminescence immune assay device | |
| CN210376404U (en) | Full-automatic detection device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |