CN109170201A - A kind of feed addictive and production method with bacteriostasis containing fructooligosaccharide and thyme extract - Google Patents

A kind of feed addictive and production method with bacteriostasis containing fructooligosaccharide and thyme extract Download PDF

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Publication number
CN109170201A
CN109170201A CN201811036077.9A CN201811036077A CN109170201A CN 109170201 A CN109170201 A CN 109170201A CN 201811036077 A CN201811036077 A CN 201811036077A CN 109170201 A CN109170201 A CN 109170201A
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China
Prior art keywords
fructooligosaccharide
thyme extract
accounts
thyme
feed addictive
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Withdrawn
Application number
CN201811036077.9A
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Chinese (zh)
Inventor
龙蕾
温丽伟
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Jiangsu Longda Biological Technology Co Ltd
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Jiangsu Longda Biological Technology Co Ltd
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Priority to CN201811036077.9A priority Critical patent/CN109170201A/en
Publication of CN109170201A publication Critical patent/CN109170201A/en
Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/60Feeding-stuffs specially adapted for particular animals for weanlings
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Physiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)

Abstract

The present invention provides a kind of with antibacterial feed addictive, it is characterised in that contains fructooligosaccharide and thyme extract.Wherein, fructooligosaccharide accounts for the 0.1~25% of total weight ratio, and thyme extract accounts for the 0.1~20% of total weight, and carrier accounts for the 55~99.8% of total weight;Its dosage in feed is 100~500g/t.This technology is to invent a kind of feed addictive with bacteriostasis.By fructooligosaccharide to the adjusting of animal intestinal tract microbial population and be combineding with each other for thyme extract bacteriostasis, it can reach protection animal intestinal tract health, promote the growth of livestock and poultry, reduce diarrhea rate and other effects.Fructooligosaccharide and thyme extract, which are carried out compounding, can reduce the use of antibiotic, ensure animal production safety and have good quality.It is the environmental type additive of a kind of " safety is efficiently stablized, controllable ".

Description

A kind of feed addition with bacteriostasis containing fructooligosaccharide and thyme extract Agent and production method
(1) technical field
The present invention relates to a kind of feed addictive and production method containing fructooligosaccharide and thyme extract, especially one Feed addictive and production method with bacteriostasis of the kind containing fructooligosaccharide and thyme extract.
(2) background technique
Containing complicated microbiota, including beneficial bacterium and harmful bacteria in animal intestinal tract, the balance that both maintains for It is particularly significant for the health of animal.In a normal equilibrium state, beneficial bacterium is dominant microflora in alimentary canal, but is digested The biobalance in road is a dynamic equilibrium, can because the age of animal, stress, the change of daily ration and some environmental factors due to change Become, once pathogen becomes dominant microflora, then lesion occurs for body, to influence animal health.Fructooligosaccharide can pass through stomach Alimentary canal rear end is reached with small intestine, is selectively utilized, makes by intestinal beneficial microbes such as Bifidobacteriums as nutrient matrix While these beneficial bacteriums obtain nutrient and are proliferated, the harmful bacterias such as salmonella and spoilage organisms are because that cannot secrete decomposable fructooligosaccharide Fructosidase be suppressed own growth.Bifidobacterium and lactobacillus fermentation generate volatile fatty acid, reduce enteron aisle PH value and redox potential, it is effective that pathogen is prevented to breed.Bifidobacterium and Bacillus acidi lactici and intestinal mucosa epithelium are thin simultaneously Born of the same parents are intimately associated, and occupy intestinal mucosa surface jointly, form a biological containment and compete living space with harmful bacteria, prevent to cause Germ invasion achievees the purpose that inhibit pathogen.
Thyme 1%-2% containing essential oil, main component be Thymol (24%-60%), carvacrol, α-terpinene, Dilute, firpene of α-ramie etc., separately containing expressed oi, protein, tannin, poly-pentose and pigment etc..Also containing there are two types of biphenyl compounds Thyme xenol I and II have and BHT (2,6- di-tert-butyl-4-methy phenol) comparable oxidation resistance.Thymol There is a very strong antibacterial activity with carvacrol, active ingredient has very strong surface-active and fat-soluble, can readily penetrate through disease Source microbial cell film, therefore cause etiology microorganism electrolyte imbalance and dead, in addition carvacrol and Thymol are in intestines The outer layer of tract epithelial cell is active, can accelerate the turnover rate of intestinal epithelial cell, reduces pathogen to intestinal epithelial cell Infection enhances the abilities of digestive and absorption to nutriment, improves the growth performance and efficiency of feed utilization of animal.
This technology compounds fructooligosaccharide and thyme extract, invents a kind of feed addition with bacteriostasis Agent.It is reachable by fructooligosaccharide to the adjusting of animal intestinal tract microbial population and be combineding with each other for thyme extract bacteriostasis To protection animal intestinal tract health, diarrhea rate is reduced, the effect of improving the immunocompetence of livestock and poultry, promote the growth of livestock and poultry.By fruit widow Sugar and thyme extract, which carry out compounding, can reduce the use of antibiotic, ensure animal production safety and have good product Matter.Natural plant extracts feed addictive is known as the environmental type additive of " safety is efficiently stablized, controllable ".Fruit is few Sugar and the feed addictive of thyme extract can substitute the use of the antibiotic of phase same-action, produce to promotion feed and animal Product safety, ensures consumer health, and the development for pushing forward feed industry comprehensively has important research significance.
(3) summary of the invention
The purpose of the present invention is to provide a kind of feed with bacteriostasis containing fructooligosaccharide and thyme extract Additive is added in feed, adjusts enteric bacteria balance in animal body, accelerates the turnover rate of intestinal epithelial cell, reduces cause of disease Infection of the body to intestinal epithelial cell enhances the abilities of digestive and absorption to nutriment, reduces diarrhea rate, promotes growth of animal, Efficiency of feed utilization is improved, illness rate and medicament residue are reduced, is a kind of safe and efficient, green novel fodder additive.
A kind of technical solution of the present invention: feed addictive containing fructooligosaccharide and thyme extract with bacteriostasis And production method, it is characterised in that it is made of the mixing of fructooligosaccharide, thyme extract and carrier;Fructooligosaccharide accounts for total weight ratio 0.1~25%, thyme extract accounts for the 0.1~20% of total weight, and carrier accounts for the 55~99.8% of total weight;It is in feed In dosage be 100~500g/t.
The fructosyl transfer activity enzyme effect that above-mentioned described fructooligosaccharide has in microorganism and plant is in sucrose Obtained from, content 5.0%~30.0%.
Above-mentioned described thyme extract, derives from thyme, content 3.0%~20.0%.
A kind of above-mentioned feed addictive with bacteriostasis containing fructooligosaccharide and thyme extract, it is characterised in that It is comprised the following production steps that
1) formula rate feeding, formula are as follows: fructooligosaccharide accounts for the 0.1~25% of weight ratio, and thyme extract accounts for weight are pressed The 0.1~20% of ratio, carrier accounts for 55~99.8%;
The fructosyl transfer activity enzyme effect that above-mentioned described fructooligosaccharide has in microorganism and plant in sucrose, Content 5.0%~30.0%;
Above-mentioned described thyme extract derives from thyme, content 3.0%~20.0%;
2) fructooligosaccharide and thyme extract are mixed step by step in proportion, until being uniformly mixed;
3) said mixture is added in carrier and is sufficiently mixed uniformly;
4) it weighs, pack.
Of the invention to be advantageous in that: 1, this feed addictive can promote in animal body beneficial bacterium in enteron aisle back segment The proliferation of proliferation, especially promotion Bifidobacterium and lactic acid bacteria enhances its immunocompetence to promote the health of animal, reduces Illness rate.2, the feed addictive can be improved efficiency of feed utilization and reached by antibacterial and protection animal intestinal tract health effect 10% or more, diarrhea rate reduces by 30% or more.3, improve cultivation safety, reduce the use of antibiotic, be it is a kind of safety, Efficiently, the feed addictive with good feeding effect and economic benefit.
(4) specific embodiment
Embodiment 1:
A kind of feed addictive with bacteriostasis containing fructooligosaccharide and thyme extract, in fructooligosaccharide and hundred Fragrant extract is added to as main active by corn, dregs of beans, fermentation soybean, plasma protein, fish meal, expanded soybean, cream In the feed that clear powder, wheat-middlings, vegetable oil, white granulated sugar, milk pastil, premix form.
A kind of above-mentioned feed addictive with bacteriostasis containing fructooligosaccharide and thyme extract, it is characterised in that It is comprised the following production steps that
1) formula rate feeding, formula are as follows: fructooligosaccharide accounts for the 5% of total weight ratio, and thyme extract accounts for total weight are pressed 10%, carrier accounts for the 85% of total weight;
The fructosyl transfer activity enzyme effect that above-mentioned described fructooligosaccharide has in microorganism and plant is in sucrose Obtained from, content 8%.
Above-mentioned described thyme extract, derives from thyme, content 14%.
2) fructooligosaccharide and thyme extract are mixed step by step in proportion, until being uniformly mixed;
3) said mixture is added in carrier and is sufficiently mixed uniformly;
4) it weighs, pack.
Test: Avain chicken 100 of selection health, uniform 7 age in days of weight are randomly divided into two groups, and one group is pair According to group, one group is experimental group.Control group fed basal diet feed, standard recipe of the test group feeding containing the said goods are raised Material, every group of 50 chickens cultivate two groups of broiler chicken 21 days under identical environment.Stop to raise 12 hours at the end of raising experiment, before government official, Every group is randomly selected 10 chickens, is butchered after weighing, and measure corresponding index.
Technical effect: in the identical situation of rearing conditions, the broiler chicken diarrhea rate for feeding feed addictive of the present invention is obvious Lower than control group.Comprehensive Experiment discovery: after feeding 21 days, test group is lower by 70.3% than control group broiler chicken diarrhea rate, test group meat The weight gain of chicken improves 9.06%, and test group feedstuff-meat ratio reduces 13.57%, Bifidobacterium, cream in test group broiler chicken caecum Acidfast bacilli improves 12.03% (P < 0.05) than control group, which improves the Intestinal Morphology of Avain chicken, And the height and gutstring staple length/Crypt depth ratio of small gutstring hair are improved to a certain extent, and obviously inhibit enteron aisle The breeding and growth of middle Escherichia coli, and then the immune system of broiler chicken is had adjusted, the healthy growth of broiler chicken is promoted, is significantly improved Culture efficiency.
Embodiment 2:
A kind of feed addictive with bacteriostasis containing fructooligosaccharide and thyme extract, in fructooligosaccharide and hundred Fragrant extract is added to as main active by corn, dregs of beans, fermentation soybean, plasma protein, fish meal, expanded soybean, cream In the feed that clear powder, wheat-middlings, vegetable oil, white granulated sugar, milk pastil, premix form.
A kind of above-mentioned feed addictive with bacteriostasis containing fructooligosaccharide and thyme extract, it is characterised in that It is comprised the following production steps that
1) formula rate feeding, formula are as follows: fructooligosaccharide accounts for the 15% of total weight ratio, and thyme extract accounts for total weight are pressed 10%, carrier accounts for the 75% of total weight;
The fructosyl transfer activity enzyme effect that above-mentioned described fructooligosaccharide has in microorganism and plant is in sucrose Obtained from, content 10%.
Above-mentioned described thyme extract, derives from thyme, content 9%.
2) fructooligosaccharide and thyme extract are mixed step by step in proportion, until being uniformly mixed;
3) said mixture is added in carrier and is sufficiently mixed uniformly;
4) it weighs, pack.
Test: being randomly divided into 2 groups for 100 weanling pigs are fifty-fifty, and weight differences are not significant (P > 0.05) between group, and one group For control group, one group is test group, every group each 50.Under identical environment, control group fed is free of fructooligosaccharide and thyme The formula forage of extract, test group feeding contain the feed of above-mentioned additive, and experimental period is 30 days.
Technical effect: in the identical situation of rearing conditions, the experimental group pig diarrhea of feed addictive of the present invention is fed Rate is significantly lower than control group, and pig fur is glossy, and growing way is very fast.Comprehensive Experiment discovery: piglet daily gain improves 7.5%, The food consumption of per gain weight has dropped 12.1%, and test group is lower by 73.9% than control group pig diarrhea rate, test group feedstuff-meat ratio Lower than control group feedstuff-meat ratio 0.52, Escherichia coli reduce 12.51% in excrement, and Bifidobacterium increases 3.30%, the feed Additive improves the quantity of beneficial bacteria in pig body, it is suppressed that and the breeding of harmful bacteria improves the general level of the health of pig, into And the growth of pig is promoted, significantly improve culture efficiency.

Claims (5)

1. a kind of feed addictive and production method with bacteriostasis containing fructooligosaccharide and thyme extract, feature It is the mixture containing following component:
--- fructooligosaccharide,
--- thyme extract.
2. feed addictive as described in claim 1, it is characterised in that: fructooligosaccharide accounts for the 0.1~25% of total weight, thyme Extract accounts for the 0.1~20% of total weight, and carrier accounts for the 55~99.8% of total weight;Its dosage in feed be 100~ 500g/t。
3. feed addictive as described in claim 1, it is characterised in that: what fructooligosaccharide had in microorganism and plant Fructosyl transfer activity enzyme effect is in sucrose;
Thyme extract derives from thyme, content 1.0%~2.0%.
4. feed addictive as described in claim 1, it is characterised in that it is comprised the following production steps that
1) formula rate feeding, formula are as follows: fructooligosaccharide accounts for the 0.1~25% of weight ratio, and thyme extract accounts for weight ratio are pressed 0.1~20%, carrier accounts for 55~99.8%;
The fructosyl transfer activity enzyme effect that above-mentioned described fructooligosaccharide has in microorganism and plant is in sucrose, content 5.0%~30.0%;
Above-mentioned described thyme extract derives from thyme, content 3.0%~20.0%;
2) fructooligosaccharide is mixed step by step in proportion with thyme extract, until being uniformly mixed;
3) said mixture is added in carrier and is sufficiently mixed uniformly;
4) it weighs, pack.
5. the additive as described in any one of claim 1-4 is used for livestock and poultry antibacterial in production, reduces diarrhea rate, protection Intestinal health, the pernicious bacteria for reducing animal and bird intestines, the purposes for improving growth performance.
CN201811036077.9A 2018-08-24 2018-08-24 A kind of feed addictive and production method with bacteriostasis containing fructooligosaccharide and thyme extract Withdrawn CN109170201A (en)

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CN201811036077.9A CN109170201A (en) 2018-08-24 2018-08-24 A kind of feed addictive and production method with bacteriostasis containing fructooligosaccharide and thyme extract

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Application Number Priority Date Filing Date Title
CN201811036077.9A CN109170201A (en) 2018-08-24 2018-08-24 A kind of feed addictive and production method with bacteriostasis containing fructooligosaccharide and thyme extract

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114982866A (en) * 2022-07-12 2022-09-02 宁夏九盛牧业科技研究院(有限公司) Premixed feed additive capable of improving diarrhea of young animals and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114982866A (en) * 2022-07-12 2022-09-02 宁夏九盛牧业科技研究院(有限公司) Premixed feed additive capable of improving diarrhea of young animals and preparation method thereof

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Application publication date: 20190111