CN109166439A - A kind of production method of the stomach section silica gel model of sheep - Google Patents

A kind of production method of the stomach section silica gel model of sheep Download PDF

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CN109166439A
CN109166439A CN201811275893.5A CN201811275893A CN109166439A CN 109166439 A CN109166439 A CN 109166439A CN 201811275893 A CN201811275893 A CN 201811275893A CN 109166439 A CN109166439 A CN 109166439A
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silicon rubber
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sheep
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CN109166439B (en
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司丽芳
李健
李梦云
陈晓光
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Henan University of Science and Technology
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    • GPHYSICS
    • G09EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09BEDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/28Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine

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Abstract

A kind of stomach section silica gel model production method of sheep, special fixative is first passed through to animal carcass perfusion fixation, nature when maintaining as in sheep body, then using the polyethylene glycol filling after fusing, stomach is splitted, stomach surface is exposed as, with special release agent brushing, silicon rubber and gypsum brushing, prepare gypsum and silicon rubber former and formpiston;Using silicon rubber good fluidity, stomach surfaces externally and internally easy to attach fine structure the characteristics of, and using the robustness of gypsum, to prepare accurate fine and smooth, the lively true organ model of structure, solve the problems, such as that the previous model sense of reality is poor.

Description

A kind of production method of the stomach section silica gel model of sheep
Technical field
The present invention relates to a kind of adults alimentary canal model production method, the stomach section silica gel of specifically a kind of sheep The production method of model.
Background technique
Animal model has morphosis similar with animal, can transmit animal morphology information.It can be used for science popularization, religion The purposes such as, exhibition.Alimentary canal is feed intake, the channel for obtaining nutrition, excretion metabolism product, studies gastral structure pair Have in improving the digestion and absorption function of animal, improving efficiency of feed utilization, reduction aquaculture cost, raising breeding efficiency and economic benefit There is important role.Sheep is a kind of economic animal, and mutton is full of nutrition, deep to be liked by broad masses of the people.And sheep belongs to and ruminates Class herbivore, gastral stomach are divided into cud, reticulum, omasum and abomasum, and structure is complicated, and are distributed compact.
Existing modelling technology mostly uses engraving process to make mold, uses plastics, silicon rubber for material, makes Organ model.The organ model made in this way, the fine structure feature of displaying organ that cannot be accurate, vivid, fine and smooth, In the presence of being not easy to restore completely, the poor technological deficiency of model reproducibility.
Summary of the invention
Technical purpose of the invention are as follows: a kind of step is provided and is simple and convenient to operate, completely, comprehensively can restore and show Show the surfaces externally and internally fine structure of the organs such as sheep cud, reticulum, omasum and abomasum in sheep stomach model, and handsome in appearance, it is solid resistance to With natural shape is clear, conducive to the production method of the stomach section silica gel model of the sheep of observation, to cooperate teaching, displaying etc. to use.
The present invention to realize the above-mentioned technical purpose, used technical solution are as follows: a kind of stomach section silica gel model of sheep Production method, comprising the following steps:
Step 1: the preparation of fixative
According to parts by weight, 2.5~7.5 parts of lauryl sodium sulfate, 10~14 parts of urea, potassium sorbate 0.4~0.6 are successively taken Part, 0.3~5.3 part of citric acid, 17~23 parts of 1,2-PD and 54.2~64.2 parts of distilled water, after dissolution is sufficiently stirred, system Fixative is obtained, it is spare;
Step 2: the preparation of release agent
According to parts by weight, 15-25 parts of emulsifying wax liquid, 0.15-0.25 parts of o-phenyl phenol preservative, vaseline 32- are successively taken 37 parts and deionized water 30-40 parts, after mixing is sufficiently stirred, release agent is made, it is spare;
Step 3: the preparation of gypsum cream
According to parts by weight, 1-2 parts of NSJF-3B rubber powder, 45-55 parts of powdered whiting, 20-30 parts of sierozem power, plain boiled water are successively taken 23-27 parts and water 50-60 parts of mud, after mixing is sufficiently stirred, gypsum cream is made, it is spare;
Step 4: the preparation of silicon rubber lotion
Be (98.8-99.2) according to weight ratio: the ratio of (0.8-1.2) takes molded silicon rubber and condensation polymer type two-component silicone rubber After mixing is sufficiently stirred, yellowish pink silicon rubber lotion is made in crosslinking agent, spare;
Step 5: the processing of preparation
It is solid to carry out perfusion to sheep corpse using the fixative of step 1 preparation later for the strong sheep of selection adult, bloodletting after anesthesia It is fixed;And oesophagus, cud, reticulum, omasum, abomasum and the duodenum in sheep corpse are completely separated, empty content and Cleaning, later, ligatures duodenal end, preparation is made, spare;
Step 6: the filling of preparation solidifies
Solid polyethylene glycol is taken, after carrying out heating and melting under the conditions of 65-75 DEG C, pours into from oesophagus and is moved made from step 5 In object sample, until oesophagus, cud, reticulum, omasum, abomasum and the duodenum in preparation are by liquid macrogol It fills to the natural form of turgor, later, naturally cools to polyethylene glycol and solidify completely and form internal model, filling is made and solidifies Preparation, it is spare;
It is taken off made from one layer of step 2 Step 7: the outer surface that filling solidifies preparation made from step 6 is uniformly brushed Mould agent, and then repeatedly silicon rubber lotion made from squeegeeing step four, the silicon rubber lotion are dynamic in filling solidification after solidifying completely Silicon rubber former is formed outside object sample, it is spare;
Step 8: the silicon rubber former external surface made from step 7 uniformly brushes release agent made from one layer of step 2, later, The gypsum cream that multiple squeegeeing step three is prepared again forms the gypsum cream former of hard after the solidification completely of gypsum cream, spare;
Step 9: by silicon rubber former made from gypsum cream former made from step 8, step 7 and filling solidification animal body Sample is splitted along center section, takes out solid polyethylene glycol internal model therein, thus the inner surface of exposure preparation;
Step 10: the inner surface for the preparation splitted in step 9 uniformly brushes release agent made from one layer of step 2, it Afterwards, then silicon rubber lotion made from multiple squeegeeing step four, after which solidifies completely, in the interior table of preparation Face forms silicon rubber formpiston, spare;
Step 11: release agent made from one layer of step 2 is uniformly brushed in the silicon rubber formpiston outer surface made from step 10, it Afterwards, then the gypsum cream of the preparation of multiple squeegeeing step three forms the gypsum cream formpiston of hard after the solidification completely of gypsum cream, spare;
Step 12: the preparation between silicon rubber formpiston and silicon rubber former is removed, later, by silicon rubber former, stone Cream cream former is assembled with silicon rubber formpiston and gypsum cream formpiston, and preparation section parietal layer can be accommodated by having inside formation The model of structural cavities;
Step 13: the cream of silicon rubber made from step 4 is perfused in the section parietal layer structural cavities of the model obtained by step 12 Liquid, after it is completely solidified into shape, along center, section is splitted, and removes the silicon rubber former, gypsum cream former and silicon rubber of model Glue formpiston and gypsum cream formpiston to get finished product sheep stomach section silica gel model.
Further, in step 6, the molecular weight of the polyethylene glycol is 6000.
Further, in step 7, the brushing number of the silicon rubber lotion is 4 times.
Further, in step 8, the brushing number of the gypsum cream is 4 times.
Further, in step 10, the brushing number of the silicon rubber lotion is 4 times.
Further, in step 11, the brushing number of the gypsum cream is 4 times.
Beneficial effect is:
1, the stomach section silica gel model of a kind of sheep prepared by the present invention, using special fixer (lauryl sodium sulfate (2.5%), Urea (12%), potassium sorbate (0.5%), citric acid (0.3%), 1,2- propylene glycol (20%), distilled water (64.2%) composition) it carries out Perfusion, animal body is unlikely to deform after perfusion, facilitates subsequent operation.
Moderate for molding silicon rubber lotion hardness, construction recovery degree is high, non-aging, deformation, and long service life. The release agent stripping result being configured to using emulsifying wax liquid, deionized water, vaseline and o-phenyl phenol preservative is good, not easy to stick Even, yield rate is improved.The stomach section silica gel model of finished product sheep is nontoxic to the human body, tasteless and nonirritant, is easy to use, is easy to protect It deposits.
2, the stomach section silica gel model of the sheep prepared by the present invention, production method is simple, low in cost, the stomach section knot of sheep Structure reduction degree is high, can clearly indicate out the fine structure of the surfaces externally and internally of the cud of sheep, reticulum, omasum and abomasum, structure Beauty, form understand naturally, being conducive to observation, facilitating teaching and showing use.
3, the special fixative formula components that the present invention uses are truly realized ring without stimulation, toxic material composition The advantages of guarantor, safe and nontoxic pair, stimulation.The preparation formula of release agent improves stripping result, mold and device when making modelling Official can be easily separated, and not stick together.The content adjustment of latex is suitable for that the speed of easily controllable gypsum sets makes in gypsum formula The operation for facilitating modelling.
4, the present invention first makes gypsum and silicon rubber former and formpiston when preparing sheep stomach model respectively;Utilize silicon rubber Good fluidity, stomach surfaces externally and internally easy to attach fine structure the characteristics of, and using gypsum robustness, promote silicon rubber former with Formpiston fits closely the solid organ of stomach, to prepare accurate fine and smooth, the lively true organ model of structure, solves previous The problem of model sense of reality difference.
Specific embodiment
Combined with specific embodiments below, the present invention will be further described in detail:
A kind of production method of the stomach section silica gel model of sheep, specific preparation step are as follows:
Step 1: fixative is by 2.5~7.5 parts, 10~14 parts of urea, 0.4~0.6 part of potassium sorbate, citric acid 0.3~5.3 Part, 17~23 parts of 1,2- propylene glycol and distilled water 54.2~64.2 form;
Step 2: release agent is prepared: 15-25 parts of emulsifying wax liquid, 0.15-0.25 parts of o-phenyl phenol preservative, vaseline 32-37 Part and deionized water 30-40 parts of composition;
Step 3: gypsum cream is prepared: 1-2 parts of NSJF-3B rubber powder, 45-55 parts of powdered whiting, 20-30 parts of sierozem power, white cement 23-27 parts, 50-60 parts of water are added to stir evenly;
Step 4: silicon rubber prepare: according to weight ratio be (98.8-99.2): the ratio of (0.8-1.2), take molded silicon rubber and After mixing is sufficiently stirred, yellowish pink silicon rubber lotion is made in condensation polymer type two-component silicone rubber crosslinking agent;
The strong sheep Step 5: selection is grown up, bloodletting after anesthesia carry out perfusion to sheep corpse using fixative prepared by step 1 It is fixed;
Step 6: completely separation sheep oesophagus, cud, reticulum, omasum, abomasum and part duodenum, emptying content, cleaning are dry Only, duodenum one end ligatures;
Step 7: heating and melting solid polyethylene glycol (molecular weight 6000) under the conditions of 65-75 DEG C, pours into from oesophagus, until oesophagus, Stomach duodenum turgor, polyethylene glycol solidifies after cooling, forms internal model;Make oesophagus, Stomach duodenum forming, keeps certainly Right form;
Step 8: the release agent prepared in the uniform squeegeeing step two of step 7 treated structural outer surface;
Step 9: the silicon rubber of the preparation of outer surface squeegeeing step four in step 8 brushing release agent, brushes 3-5 after, it is described 3-5 all over brush be brushed each time soon solidification when and then brush next time, brushed for the last time to silicon rubber solidify Afterwards, the silicon rubber former of oesophagus, Stomach duodenum outer surface is made;
Step 10: the release agent of the preparation of silicon rubber outer surface squeegeeing step two in step 9 brushing;
Step 11: the gypsum cream of the preparation of release agent outer surface squeegeeing step three in step 10 brushing, brushes 3-5 after, It is solid to gypsum curdling, the gypsum cream former of oesophagus, Stomach duodenum outer surface is made;
Step 12: the silicon rubber former and gypsum cream former that step 9 and step 11 make are splitted along center section;And Oesophagus, Stomach duodenum are splitted along center section;Take out solid polyethylene glycol internal model;In exposure oesophagus, Stomach duodenum Surface;
Step 13: the release agent that the uniform squeegeeing step two of oesophagus, Stomach duodenum inner surface is prepared;
Step 14: the silicon of the preparation of outer surface squeegeeing step four in step 13 oesophagus, Stomach duodenum inner surface release agent Rubber brushes 3-5 after, solidifies to silicon rubber, the silicon rubber formpiston of oesophagus, Stomach duodenum inner surface is made;
Step 15: uniformly being brushed in the oesophagus of step 14 production, the silicon rubber formpiston outer surface of Stomach duodenum inner surface The release agent that step 2 is prepared;
Step 16: being applied in the oesophagus of step 15 production, the silicon rubber formpiston release agent outer surface of Stomach duodenum inner surface The gypsum cream that brush step 3 is prepared, brushes 3-5 after, solid to gypsum curdling, and the stone of oesophagus, Stomach duodenum inner surface is made Cream cream formpiston;
Step 17: after removing oesophagus, Stomach duodenum, by the silicon rubber former of outer surface and gypsum cream former and inner surface Silicon rubber formpiston and gypsum cream formpiston, be combined into the model of oesophagus, Stomach duodenum, oesophagus, stomach, ten can be accommodated by inside having The cavity of two duodenum 12 section parietal layer structures;
Step 18: the oesophagus made to step 10 seven, Stomach duodenum parietal layer structural model sky intra-bladder instillation step 4 are prepared Silicon rubber, to its solidification forming;Longitudinal direction is splitted, and model former and formpiston are removed, and exposes the oesophagus, stomach, 12 fingers of production Intestinal wall layer cross-section structure model.
Model production method of the invention, first by special fixative to animal carcass perfusion fixation, maintain for Nature when in sheep body splits stomach, exposes as stomach surface, with special then using the polyethylene glycol filling after fusing Release agent brushing, silicon rubber and gypsum brushing, prepare gypsum and silicon rubber former and formpiston;Using silicon rubber good fluidity, easily The characteristics of being bonded the fine structure of stomach surfaces externally and internally, and using the robustness of gypsum, so that it is accurate fine and smooth, lively to prepare structure True organ model.Solve the problems, such as that the previous model sense of reality is poor.
Embodiment 1
A kind of production method of the stomach section silica gel model of sheep, specific preparation step are as follows:
Step 1: fixative is by lauryl sodium sulfate (2.5%), urea (12%), potassium sorbate (0.5%), citric acid (0.3%), 1,2- propylene glycol (20%), distilled water (64.2%) composition;
Step 2: release agent is prepared: emulsifying wax liquid 15%;Deionized water 40%;Vaseline 35%;O-phenyl phenol preservative 0.2%;
Step 3: gypsum cream is prepared: NSJF-3B rubber powder 1%, powdered whiting 50%, sierozem power 25%, white cement 25% add water 60 parts stir evenly;
Step 4: silicon rubber is prepared: molded silicon rubber 99%, it is interior to add condensation polymer type two-component silicone rubber (RTV-2) crosslinking agent (1%), yellowish pink silicon rubber is made;
Step 5: after selection anesthesia, by the corpse for the adult sheep that perfusion fixation is put to death;
Step 6: completely separating sheep part oesophagus, cud, reticulum, omasum, abomasum and part duodenum, content is emptied, clearly Wash clean, the ligation of duodenum one end;
Step 7: 70 DEG C of heating and melting solid polyethylene glycols (molecular weight 6000), pour into from oesophagus, until oesophagus, stomach, 12 fingers Intestines turgor, polyethylene glycol solidifies after cooling, forms internal model;Make oesophagus, Stomach duodenum forming, keeps natural form;
Step 8: the release agent prepared in the uniform squeegeeing step two of step 7 treated body structure surface;
Step 9: the silicon rubber of the preparation of outer surface squeegeeing step four in step 8 brushing release agent, after brushing 4 times, to silicon rubber Gelling is solid, and the silicon rubber former of oesophagus, Stomach duodenum outer surface is made;
Step 10: the release agent of the preparation of silicon rubber outer surface squeegeeing step two in step 9 brushing;
Step 11: the gypsum cream of the preparation of release agent outer surface squeegeeing step three in step 10 brushing, after brushing 4 times, to Gypsum curdling is solid, and the gypsum cream former of oesophagus, Stomach duodenum outer surface is made;
Step 12: the silicon rubber former and gypsum cream former that step 9 and step 11 make are splitted along center section;And Oesophagus, Stomach duodenum are splitted along center section;Take out solid polyethylene glycol internal model;In exposure oesophagus, Stomach duodenum Surface;
Step 13: the release agent that the uniform squeegeeing step two of oesophagus, Stomach duodenum inner surface is prepared;
Step 14: the silicon of the preparation of outer surface squeegeeing step four in step 13 oesophagus, Stomach duodenum inner surface release agent Rubber after brushing 4 times, solidifies to silicon rubber, the silicon rubber formpiston of oesophagus, Stomach duodenum inner surface is made;
Step 15: uniformly being brushed in the oesophagus of step 14 production, the silicon rubber formpiston outer surface of Stomach duodenum inner surface The release agent that step 2 is prepared;
Step 16: being applied in the oesophagus of step 15 production, the silicon rubber formpiston release agent outer surface of Stomach duodenum inner surface The gypsum cream that brush step 3 is prepared, it is solid to gypsum curdling after brushing 4 times, the gypsum of oesophagus, Stomach duodenum inner surface is made Newborn formpiston;
Step 17: after removing oesophagus, Stomach duodenum, by the silicon rubber former of outer surface and gypsum cream former and inner surface Silicon rubber formpiston and gypsum cream formpiston, be combined into the model of oesophagus, Stomach duodenum, oesophagus, stomach, ten can be accommodated by inside having The cavity of two duodenum 12 section parietal layer structures;
Step 18: the oesophagus made to step 10 seven, Stomach duodenum parietal layer structural model sky intra-bladder instillation step 4 are prepared Silicon rubber, to its solidification forming;Longitudinal direction is splitted, and model former and formpiston are removed, and exposes the oesophagus, stomach, 12 fingers of production Intestinal wall layer cross-section structure model.
Embodiment 2
A kind of production method of the stomach section silica gel model of sheep, specific preparation step are as follows:
Step 1: fixative is by lauryl sodium sulfate (7.5%), urea (12%), potassium sorbate (0.5%), citric acid (5.3%), 1,2- propylene glycol (20%), distilled water (54.2%) composition;
Step 2: release agent is prepared: emulsifying wax liquid: 25%;Deionized water: 30%;Vaseline 35%;O-phenyl phenol preservative: 0.2%;
Step 3: gypsum cream is prepared: NSJF-3B rubber powder 2%, powdered whiting 50%, sierozem power 25%, white cement 24% add water 52 parts stir evenly;
Step 4: molded silicon rubber 99%, interior to add condensation polymer type two-component silicone rubber (RTV-2) crosslinking agent 1%, yellowish pink is made Silicon rubber;
Step 5: after selection anesthesia, by the corpse for the adult sheep that perfusion fixation is put to death;
Step 6: completely separating sheep part oesophagus, cud, reticulum, omasum, abomasum and part duodenum, content is emptied, clearly Wash clean, the ligation of duodenum one end;
Step 7: 70 DEG C of heating and melting solid polyethylene glycols (molecular weight 6000), pour into from oesophagus, until oesophagus, stomach, 12 fingers Intestines turgor, polyethylene glycol solidifies after cooling, forms internal model;Make oesophagus, Stomach duodenum forming, keeps natural form;
Step 8: the release agent prepared in the uniform squeegeeing step two of step 7 treated body structure surface;
Step 9: the silicon rubber of the preparation of outer surface squeegeeing step four in step 8 brushing release agent, after brushing 4 times, to silicon rubber Gelling is solid, and the silicon rubber former of oesophagus, Stomach duodenum outer surface is made;
Step 10: the release agent of the preparation of silicon rubber outer surface squeegeeing step two in step 9 brushing;
Step 11: the gypsum cream of the preparation of release agent outer surface squeegeeing step three in step 10 brushing, after brushing 4 times, to Gypsum curdling is solid, and the gypsum cream former of oesophagus, Stomach duodenum outer surface is made;
Step 12: the silicon rubber former and gypsum cream former that step 9 and step 11 make are splitted along center section;And Oesophagus, Stomach duodenum are splitted along center section;Take out solid polyethylene glycol internal model;In exposure oesophagus, Stomach duodenum Surface;
Step 13: the release agent that the uniform squeegeeing step two of oesophagus, Stomach duodenum inner surface is prepared;
Step 14: the silicon of the preparation of outer surface squeegeeing step four in step 13 oesophagus, Stomach duodenum inner surface release agent Rubber after brushing 4 times, solidifies to silicon rubber, the silicon rubber formpiston of oesophagus, Stomach duodenum inner surface is made;
Step 15: uniformly being brushed in the oesophagus of step 14 production, the silicon rubber formpiston outer surface of Stomach duodenum inner surface The release agent that step 2 is prepared;
Step 16: being applied in the oesophagus of step 15 production, the silicon rubber formpiston release agent outer surface of Stomach duodenum inner surface The gypsum cream that brush step 3 is prepared, it is solid to gypsum curdling after brushing 4 times, the gypsum of oesophagus, Stomach duodenum inner surface is made Newborn formpiston;
Step 17: after removing oesophagus, Stomach duodenum, by the silicon rubber former of outer surface and gypsum cream former and inner surface Silicon rubber formpiston and gypsum cream formpiston, be combined into the model of oesophagus, Stomach duodenum, oesophagus, stomach, ten can be accommodated by inside having The cavity of two duodenum 12 section parietal layer structures;
Step 18: the oesophagus made to step 10 seven, Stomach duodenum parietal layer structural model sky intra-bladder instillation step 4 are prepared Silicon rubber, to its solidification forming;Longitudinal direction is splitted, and model former and formpiston are removed, and exposes the oesophagus, stomach, 12 fingers of production Intestinal wall layer cross-section structure model.
Embodiment 3
A kind of production method of the stomach section silica gel model of sheep, specific preparation step are as follows:
Step 1: fixative is by 5 parts, 10 parts of urea, 0.6 part of potassium sorbate, 2 parts of citric acid, 17 parts of 1,2- propylene glycol and distillation Water 60 forms;
Step 2: release agent is prepared: 20 parts of emulsifying wax liquid, 0.15 part of o-phenyl phenol preservative, 37 parts of vaseline and deionization 35 parts of water compositions;
Step 3: gypsum cream is prepared: 1.5 parts of NSJF-3B rubber powder, 45 parts of powdered whiting, 20 parts of sierozem power, 23 parts of white cement, 50 parts of water are added to stir evenly;
Step 4: silicon rubber is prepared: the ratio for being 98.8:1.2 according to weight ratio takes molded silicon rubber and condensation polymer type two-component silicon After mixing is sufficiently stirred, yellowish pink silicon rubber lotion is made in rubber crosslinker;
The strong sheep Step 5: selection is grown up, bloodletting after anesthesia carry out perfusion to sheep corpse using fixative prepared by step 1 It is fixed;
Step 6: completely separation sheep oesophagus, cud, reticulum, omasum, abomasum and part duodenum, emptying content, cleaning are dry Only, duodenum one end ligatures;
Step 7: heating and melting solid polyethylene glycol (molecular weight 6000) under the conditions of 65 DEG C, pours into from oesophagus, until oesophagus, stomach, Duodenum turgor, polyethylene glycol solidifies after cooling, forms internal model;Make oesophagus, Stomach duodenum forming, keeps nature Form;
Step 8: the release agent prepared in the uniform squeegeeing step two of step 7 treated structural outer surface;
Step 9: the silicon rubber of the preparation of outer surface squeegeeing step four in step 8 brushing release agent, after brushing 3 times, to silicon rubber Gelling is solid, and the silicon rubber former of oesophagus, Stomach duodenum outer surface is made;
Step 10: the release agent of the preparation of silicon rubber outer surface squeegeeing step two in step 9 brushing;
Step 11: the gypsum cream of the preparation of release agent outer surface squeegeeing step three in step 10 brushing, after brushing 3 times, to Gypsum curdling is solid, and the gypsum cream former of oesophagus, Stomach duodenum outer surface is made;
Step 12: the silicon rubber former and gypsum cream former that step 9 and step 11 make are splitted along center section;And Oesophagus, Stomach duodenum are splitted along center section;Take out solid polyethylene glycol internal model;In exposure oesophagus, Stomach duodenum Surface;
Step 13: the release agent that the uniform squeegeeing step two of oesophagus, Stomach duodenum inner surface is prepared;
Step 14: the silicon of the preparation of outer surface squeegeeing step four in step 13 oesophagus, Stomach duodenum inner surface release agent Rubber after brushing 5 times, solidifies to silicon rubber, the silicon rubber formpiston of oesophagus, Stomach duodenum inner surface is made;
Step 15: uniformly being brushed in the oesophagus of step 14 production, the silicon rubber formpiston outer surface of Stomach duodenum inner surface The release agent that step 2 is prepared;
Step 16: being applied in the oesophagus of step 15 production, the silicon rubber formpiston release agent outer surface of Stomach duodenum inner surface The gypsum cream that brush step 3 is prepared, it is solid to gypsum curdling after brushing 5 times, the gypsum of oesophagus, Stomach duodenum inner surface is made Newborn formpiston;
Step 17: after removing oesophagus, Stomach duodenum, by the silicon rubber former of outer surface and gypsum cream former and inner surface Silicon rubber formpiston and gypsum cream formpiston, be combined into the model of oesophagus, Stomach duodenum, oesophagus, stomach, ten can be accommodated by inside having The cavity of two duodenum 12 section parietal layer structures;
Step 18: the oesophagus made to step 10 seven, Stomach duodenum parietal layer structural model sky intra-bladder instillation step 4 are prepared Silicon rubber, to its solidification forming;Longitudinal direction is splitted, and model former and formpiston are removed, and exposes the oesophagus, stomach, 12 fingers of production Intestinal wall layer cross-section structure model.
Embodiment 4
A kind of production method of the stomach section silica gel model of sheep, specific preparation step are as follows:
Step 1: fixative is by 6 parts, 14 parts of urea, 0.4 part of potassium sorbate, 1 part of citric acid, 23 parts of 1,2- propylene glycol and distillation Water 55 forms;
Step 2: release agent is prepared: 22 parts of emulsifying wax liquid, 0.25 part of o-phenyl phenol preservative, 32 parts of vaseline and deionization 33 parts of water compositions;
Step 3: gypsum cream is prepared: 1.2 parts of NSJF-3B rubber powder, 55 parts of powdered whiting, 30 parts of sierozem power, 27 parts of white cement, 55 parts of water are added to stir evenly;
Step 4: silicon rubber is prepared: the ratio for being 99.2:0.8 according to weight ratio takes molded silicon rubber and condensation polymer type two-component silicon After mixing is sufficiently stirred, yellowish pink silicon rubber lotion is made in rubber crosslinker;
The strong sheep Step 5: selection is grown up, bloodletting after anesthesia carry out perfusion to sheep corpse using fixative prepared by step 1 It is fixed;
Step 6: completely separation sheep oesophagus, cud, reticulum, omasum, abomasum and part duodenum, emptying content, cleaning are dry Only, duodenum one end ligatures;
Step 7: heating and melting solid polyethylene glycol (molecular weight 6000) under the conditions of 75 DEG C, pours into from oesophagus, until oesophagus, stomach, Duodenum turgor, polyethylene glycol solidifies after cooling, forms internal model;Make oesophagus, Stomach duodenum forming, keeps nature Form;
Step 8: the release agent prepared in the uniform squeegeeing step two of step 7 treated structural outer surface;
Step 9: the silicon rubber of the preparation of outer surface squeegeeing step four in step 8 brushing release agent, after brushing 5 times, to silicon rubber Gelling is solid, and the silicon rubber former of oesophagus, Stomach duodenum outer surface is made;
Step 10: the release agent of the preparation of silicon rubber outer surface squeegeeing step two in step 9 brushing;
Step 11: the gypsum cream of the preparation of release agent outer surface squeegeeing step three in step 10 brushing, after brushing 3 times, to Gypsum curdling is solid, and the gypsum cream former of oesophagus, Stomach duodenum outer surface is made;
Step 12: the silicon rubber former and gypsum cream former that step 9 and step 11 make are splitted along center section;And Oesophagus, Stomach duodenum are splitted along center section;Take out solid polyethylene glycol internal model;In exposure oesophagus, Stomach duodenum Surface;
Step 13: the release agent that the uniform squeegeeing step two of oesophagus, Stomach duodenum inner surface is prepared;
Step 14: the silicon of the preparation of outer surface squeegeeing step four in step 13 oesophagus, Stomach duodenum inner surface release agent Rubber after brushing 3 times, solidifies to silicon rubber, the silicon rubber formpiston of oesophagus, Stomach duodenum inner surface is made;
Step 15: uniformly being brushed in the oesophagus of step 14 production, the silicon rubber formpiston outer surface of Stomach duodenum inner surface The release agent that step 2 is prepared;
Step 16: being applied in the oesophagus of step 15 production, the silicon rubber formpiston release agent outer surface of Stomach duodenum inner surface The gypsum cream that brush step 3 is prepared, it is solid to gypsum curdling after brushing 3 times, the gypsum of oesophagus, Stomach duodenum inner surface is made Newborn formpiston;
Step 17: after removing oesophagus, Stomach duodenum, by the silicon rubber former of outer surface and gypsum cream former and inner surface Silicon rubber formpiston and gypsum cream formpiston, be combined into the model of oesophagus, Stomach duodenum, oesophagus, stomach, ten can be accommodated by inside having The cavity of two duodenum 12 section parietal layer structures;
Step 18: the oesophagus made to step 10 seven, Stomach duodenum parietal layer structural model sky intra-bladder instillation step 4 are prepared Silicon rubber, to its solidification forming;Longitudinal direction is splitted, and model former and formpiston are removed, and exposes the oesophagus, stomach, 12 fingers of production Intestinal wall layer cross-section structure model.

Claims (6)

1. a kind of production method of the stomach section silica gel model of sheep, which comprises the following steps:
Step 1: the preparation of fixative
According to parts by weight, 2.5~7.5 parts of lauryl sodium sulfate, 10~14 parts of urea, potassium sorbate 0.4~0.6 are successively taken Part, 0.3~5.3 part of citric acid, 17~23 parts of 1,2-PD and 54.2~64.2 parts of distilled water, after dissolution is sufficiently stirred, system Fixative is obtained, it is spare;
Step 2: the preparation of release agent
According to parts by weight, 15-25 parts of emulsifying wax liquid, 0.15-0.25 parts of o-phenyl phenol preservative, vaseline 32- are successively taken 37 parts and deionized water 30-40 parts, after mixing is sufficiently stirred, release agent is made, it is spare;
Step 3: the preparation of gypsum cream
According to parts by weight, 1-2 parts of NSJF-3B rubber powder, 45-55 parts of powdered whiting, 20-30 parts of sierozem power, plain boiled water are successively taken 23-27 parts and water 50-60 parts of mud, after mixing is sufficiently stirred, gypsum cream is made, it is spare;
Step 4: the preparation of silicon rubber lotion
Be (98.8-99.2) according to weight ratio: the ratio of (0.8-1.2) takes molded silicon rubber and condensation polymer type two-component silicone rubber After mixing is sufficiently stirred, yellowish pink silicon rubber lotion is made in crosslinking agent, spare;
Step 5: the processing of preparation
It is solid to carry out perfusion to sheep corpse using the fixative of step 1 preparation later for the strong sheep of selection adult, bloodletting after anesthesia It is fixed;And oesophagus, cud, reticulum, omasum, abomasum and the duodenum in sheep corpse are completely separated, empty content and Cleaning, later, ligatures duodenal end, preparation is made, spare;
Step 6: the filling of preparation solidifies
Solid polyethylene glycol is taken, after carrying out heating and melting under the conditions of 65-75 DEG C, pours into from oesophagus and is moved made from step 5 In object sample, until oesophagus, cud, reticulum, omasum, abomasum and the duodenum in preparation are by liquid macrogol It fills to the natural form of turgor, later, naturally cools to polyethylene glycol and solidify completely and form internal model, filling is made and solidifies Preparation, it is spare;
It is taken off made from one layer of step 2 Step 7: the outer surface that filling solidifies preparation made from step 6 is uniformly brushed Mould agent, and then repeatedly silicon rubber lotion made from squeegeeing step four, the silicon rubber lotion are dynamic in filling solidification after solidifying completely Silicon rubber former is formed outside object sample, it is spare;
Step 8: the silicon rubber former external surface made from step 7 uniformly brushes release agent made from one layer of step 2, later, The gypsum cream that multiple squeegeeing step three is prepared again forms the gypsum cream former of hard after the solidification completely of gypsum cream, spare;
Step 9: by silicon rubber former made from gypsum cream former made from step 8, step 7 and filling solidification animal body Sample is splitted along center section, takes out solid polyethylene glycol internal model therein, thus the inner surface of exposure preparation;
Step 10: the inner surface for the preparation splitted in step 9 uniformly brushes release agent made from one layer of step 2, it Afterwards, then silicon rubber lotion made from multiple squeegeeing step four, after which solidifies completely, in the interior table of preparation Face forms silicon rubber formpiston, spare;
Step 11: release agent made from one layer of step 2 is uniformly brushed in the silicon rubber formpiston outer surface made from step 10, it Afterwards, then the gypsum cream of the preparation of multiple squeegeeing step three forms the gypsum cream formpiston of hard after the solidification completely of gypsum cream, spare;
Step 12: the preparation between silicon rubber formpiston and silicon rubber former is removed, later, by silicon rubber former, stone Cream cream former is assembled with silicon rubber formpiston and gypsum cream formpiston, and preparation section parietal layer can be accommodated by having inside formation The model of structural cavities;
Step 13: the cream of silicon rubber made from step 4 is perfused in the section parietal layer structural cavities of the model obtained by step 12 Liquid, after it is completely solidified into shape, along center, section is splitted, and removes the silicon rubber former, gypsum cream former and silicon rubber of model Glue formpiston and gypsum cream formpiston to get finished product sheep stomach section silica gel model.
2. a kind of production method of the stomach section silica gel model of sheep as described in claim 1, it is characterised in that: in step 6 In, the molecular weight of the polyethylene glycol is 6000.
3. a kind of production method of the stomach section silica gel model of sheep as described in claim 1, it is characterised in that: in step 7 In, the brushing number of the silicon rubber lotion is 4 times.
4. a kind of production method of the stomach section silica gel model of sheep as described in claim 1, it is characterised in that: in step 8 In, the brushing number of the gypsum cream is 4 times.
5. a kind of production method of the stomach section silica gel model of sheep as described in claim 1, it is characterised in that: in step 10 In, the brushing number of the silicon rubber lotion is 4 times.
6. a kind of production method of the stomach section silica gel model of sheep as described in claim 1, it is characterised in that: in step 11 In, the brushing number of the gypsum cream is 4 times.
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109615994A (en) * 2019-01-25 2019-04-12 胡岳 A kind of medical instruments and equipment development real training human body Bionics Bone bone model production method
CN109859601A (en) * 2019-04-04 2019-06-07 江苏农牧科技职业学院 The method of the alginates gap filler production coloured internal organs disjunctor exsiccata of buffalo multisystem

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2101926U (en) * 1991-09-10 1992-04-15 温州市标本模型厂 Animal imitating mould
CN103601844A (en) * 2013-11-14 2014-02-26 大连市金贵缘科技开发有限公司 Novel animal specimen preservation gel as well as preparation method and use thereof
CN103688152A (en) * 2011-05-02 2014-03-26 乔斯·卡洛斯·拉潘那 Fixative solution, for fixation and preservation of biological samples
CN104041482A (en) * 2014-04-30 2014-09-17 大连大学 Manufacturing method of lepidopteron plastinated specimens
US20150061185A1 (en) * 2013-08-28 2015-03-05 Jj Rabbit Llc Manufacturing method for container with artificial creatures
CN104904706A (en) * 2015-04-22 2015-09-16 青岛农业大学 Formaldehyde-free animal specimen fixed liquid and preparation method thereof
CN105355127A (en) * 2015-12-03 2016-02-24 河南科技大学 Mathematical modeling-based adult rat tail vein injection model fabricating method
CN105702146A (en) * 2015-12-31 2016-06-22 南通东概念新材料有限公司 Bionic dynamic mouse stomach-duodenum digestive system simulation device and simulation experiment method
CN207852171U (en) * 2018-06-06 2018-09-11 中粮营养健康研究院有限公司 A kind of flexibility people oesophagus, Stomach duodenum and small intestine Integrated Model

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2101926U (en) * 1991-09-10 1992-04-15 温州市标本模型厂 Animal imitating mould
CN103688152A (en) * 2011-05-02 2014-03-26 乔斯·卡洛斯·拉潘那 Fixative solution, for fixation and preservation of biological samples
US20150061185A1 (en) * 2013-08-28 2015-03-05 Jj Rabbit Llc Manufacturing method for container with artificial creatures
CN103601844A (en) * 2013-11-14 2014-02-26 大连市金贵缘科技开发有限公司 Novel animal specimen preservation gel as well as preparation method and use thereof
CN104041482A (en) * 2014-04-30 2014-09-17 大连大学 Manufacturing method of lepidopteron plastinated specimens
CN104904706A (en) * 2015-04-22 2015-09-16 青岛农业大学 Formaldehyde-free animal specimen fixed liquid and preparation method thereof
CN105355127A (en) * 2015-12-03 2016-02-24 河南科技大学 Mathematical modeling-based adult rat tail vein injection model fabricating method
CN105702146A (en) * 2015-12-31 2016-06-22 南通东概念新材料有限公司 Bionic dynamic mouse stomach-duodenum digestive system simulation device and simulation experiment method
CN207852171U (en) * 2018-06-06 2018-09-11 中粮营养健康研究院有限公司 A kind of flexibility people oesophagus, Stomach duodenum and small intestine Integrated Model

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
JIANLI,HONGWEIWANG,JILIANGZHANG,BIANHUAZHOU,LIFANGSI: "Abnormal secretion of reproductive hormones and antioxidant status involved in quinestrol-induced reproductive toxicity in adult male rat", 《TISSUE AND CELL》 *
俞仰青,张兆丰: "《生物模型制作》", 31 January 1992, 上海:上海教育出版社 *
司丽芳,夏广军,李占生,李相能: "羊心脏塑化标本制作及其在解剖组织学教学中的应用", 《羊心脏塑化标本制作及其在解剖组织学教学中的应用 *
张治国: "《塑料高分子溶液成成型技术问答》", 31 January 2012, 北京:印刷工业出版社 *
王淼: "《生物化学》", 31 January 2017, 北京:中国轻工业出版社 *
蔡雪彦,吕端远,李少华,欧伟,吴天秀,张一桥: "脑室铸型的翻模与多次复制", 《解剖学研究》 *
薛大权,王振军,肖厚平,缪立德: "《聚乙二醇在医药学领域的应用于技术》", 30 April 2011, 武汉:华中科技大学出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109615994A (en) * 2019-01-25 2019-04-12 胡岳 A kind of medical instruments and equipment development real training human body Bionics Bone bone model production method
CN109859601A (en) * 2019-04-04 2019-06-07 江苏农牧科技职业学院 The method of the alginates gap filler production coloured internal organs disjunctor exsiccata of buffalo multisystem

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