CN109148255B - 用于质谱法的具有伸长捕集区域的微型带电粒子阱 - Google Patents

用于质谱法的具有伸长捕集区域的微型带电粒子阱 Download PDF

Info

Publication number
CN109148255B
CN109148255B CN201810784433.9A CN201810784433A CN109148255B CN 109148255 B CN109148255 B CN 109148255B CN 201810784433 A CN201810784433 A CN 201810784433A CN 109148255 B CN109148255 B CN 109148255B
Authority
CN
China
Prior art keywords
end cap
aperture
electrode
ion
trap
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201810784433.9A
Other languages
English (en)
Chinese (zh)
Other versions
CN109148255A (zh
Inventor
J.M.拉姆齐
K.舒尔策
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of North Carolina at Chapel Hill
Original Assignee
University of North Carolina at Chapel Hill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of North Carolina at Chapel Hill filed Critical University of North Carolina at Chapel Hill
Publication of CN109148255A publication Critical patent/CN109148255A/zh
Application granted granted Critical
Publication of CN109148255B publication Critical patent/CN109148255B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/4245—Electrostatic ion traps
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/424—Three-dimensional ion traps, i.e. comprising end-cap and ring electrodes
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0013—Miniaturised spectrometers, e.g. having smaller than usual scale, integrated conventional components
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0031—Step by step routines describing the use of the apparatus
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/422—Two-dimensional RF ion traps
    • H01J49/4235—Stacked rings or stacked plates
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/4255—Device types with particular constructional features
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
CN201810784433.9A 2013-03-15 2013-05-21 用于质谱法的具有伸长捕集区域的微型带电粒子阱 Active CN109148255B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/840,653 US8878127B2 (en) 2013-03-15 2013-03-15 Miniature charged particle trap with elongated trapping region for mass spectrometry
US13/840653 2013-03-15
CN201380076616.0A CN105190827B (zh) 2013-03-15 2013-05-21 用于质谱法的具有伸长捕集区域的微型带电粒子阱

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201380076616.0A Division CN105190827B (zh) 2013-03-15 2013-05-21 用于质谱法的具有伸长捕集区域的微型带电粒子阱

Publications (2)

Publication Number Publication Date
CN109148255A CN109148255A (zh) 2019-01-04
CN109148255B true CN109148255B (zh) 2021-10-29

Family

ID=51523398

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201810784433.9A Active CN109148255B (zh) 2013-03-15 2013-05-21 用于质谱法的具有伸长捕集区域的微型带电粒子阱
CN201380076616.0A Active CN105190827B (zh) 2013-03-15 2013-05-21 用于质谱法的具有伸长捕集区域的微型带电粒子阱

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201380076616.0A Active CN105190827B (zh) 2013-03-15 2013-05-21 用于质谱法的具有伸长捕集区域的微型带电粒子阱

Country Status (5)

Country Link
US (5) US8878127B2 (cg-RX-API-DMAC7.html)
EP (1) EP2973650B1 (cg-RX-API-DMAC7.html)
JP (4) JP6759095B2 (cg-RX-API-DMAC7.html)
CN (2) CN109148255B (cg-RX-API-DMAC7.html)
WO (1) WO2014143101A1 (cg-RX-API-DMAC7.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8878127B2 (en) 2013-03-15 2014-11-04 The University Of North Carolina Of Chapel Hill Miniature charged particle trap with elongated trapping region for mass spectrometry
US9711341B2 (en) 2014-06-10 2017-07-18 The University Of North Carolina At Chapel Hill Mass spectrometry systems with convective flow of buffer gas for enhanced signals and related methods
US9406492B1 (en) 2015-05-12 2016-08-02 The University Of North Carolina At Chapel Hill Electrospray ionization interface to high pressure mass spectrometry and related methods
US11348778B2 (en) 2015-11-02 2022-05-31 Purdue Research Foundation Precursor and neutral loss scan in an ion trap
US9932825B1 (en) 2016-10-05 2018-04-03 Schlumberger Technology Corporation Gas chromatograph mass spectrometer for downhole applications
US10253624B2 (en) 2016-10-05 2019-04-09 Schlumberger Technology Corporation Methods of applications for a mass spectrometer in combination with a gas chromatograph
US10242857B2 (en) 2017-08-31 2019-03-26 The University Of North Carolina At Chapel Hill Ion traps with Y-directional ion manipulation for mass spectrometry and related mass spectrometry systems and methods
GB2569639B (en) 2017-12-21 2020-06-03 Thermo Fisher Scient Bremen Gmbh Ion supply system and method to control an ion supply system
EP3751269A1 (en) * 2018-02-09 2020-12-16 Hamamatsu Photonics K.K. Sample supporting body, method for ionizing sample, and mass spectrometry method
CN110828022B (zh) 2018-08-14 2021-11-19 华为技术有限公司 离子光腔耦合系统及方法
US11764051B2 (en) 2019-04-02 2023-09-19 Georgia Tech Research Corporation Linear quadrupole ion trap mass analyzer
CN114050102A (zh) * 2021-11-10 2022-02-15 中船重工安谱(湖北)仪器有限公司 一种离子阱质量分析器及用于高压质谱的质量分析装置

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101330965A (zh) * 2005-12-13 2008-12-24 杨百翰大学 小型环形射频离子阱质量分析器
CN102884608A (zh) * 2010-01-15 2013-01-16 莱克公司 离子阱质谱仪

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT528250A (cg-RX-API-DMAC7.html) 1953-12-24
US5051582A (en) * 1989-09-06 1991-09-24 The United States Of America As Represented By The Secretary Of The Air Force Method for the production of size, structure and composition of specific-cluster ions
US5118950A (en) * 1989-12-29 1992-06-02 The United States Of America As Represented By The Secretary Of The Air Force Cluster ion synthesis and confinement in hybrid ion trap arrays
US5206506A (en) * 1991-02-12 1993-04-27 Kirchner Nicholas J Ion processing: control and analysis
US5248883A (en) * 1991-05-30 1993-09-28 International Business Machines Corporation Ion traps of mono- or multi-planar geometry and planar ion trap devices
US5401962A (en) 1993-06-14 1995-03-28 Ferran Scientific Residual gas sensor utilizing a miniature quadrupole array
EP0846190A1 (en) * 1995-06-13 1998-06-10 Massively Parallel Instruments, Inc. Improved parallel ion optics and apparatus for high current low energy ion beams
DE19523860A1 (de) * 1995-06-30 1997-01-02 Bruker Franzen Analytik Gmbh Ionenfallen-Massenspektrometer mit vakuum-externer Ionenerzeugung
US6310436B1 (en) * 1995-09-22 2001-10-30 Gl Displays, Inc. Cold cathode fluorescent lamp and display
US5596193A (en) * 1995-10-11 1997-01-21 California Institute Of Technology Miniature quadrupole mass spectrometer array
US5866901A (en) * 1996-12-05 1999-02-02 Mks Instruments, Inc. Apparatus for and method of ion detection using electron multiplier over a range of high pressures
US5793091A (en) * 1996-12-13 1998-08-11 International Business Machines Corporation Parallel architecture for quantum computers using ion trap arrays
JP3656239B2 (ja) * 1997-01-28 2005-06-08 株式会社島津製作所 イオントラップ質量分析装置
US6157031A (en) 1997-09-17 2000-12-05 California Institute Of Technology Quadropole mass analyzer with linear ion trap
US6072182A (en) 1998-10-01 2000-06-06 California Institute Of Technology High-efficiency electron ionizer for a mass spectrometer array
JP2003507874A (ja) 1999-08-26 2003-02-25 ユニバーシティ オブ ニュー ハンプシャー 多段型の質量分析計
US6469298B1 (en) * 1999-09-20 2002-10-22 Ut-Battelle, Llc Microscale ion trap mass spectrometer
US7320593B2 (en) * 2000-03-08 2008-01-22 Tir Systems Ltd. Light emitting diode light source for curing dental composites
US6545268B1 (en) * 2000-04-10 2003-04-08 Perseptive Biosystems Preparation of ion pulse for time-of-flight and for tandem time-of-flight mass analysis
US6762406B2 (en) 2000-05-25 2004-07-13 Purdue Research Foundation Ion trap array mass spectrometer
JP4631219B2 (ja) * 2001-06-26 2011-02-16 株式会社島津製作所 イオントラップ型質量分析装置
GB2381653A (en) 2001-11-05 2003-05-07 Shimadzu Res Lab Europe Ltd A quadrupole ion trap device and methods of operating a quadrupole ion trap device
US6870158B1 (en) * 2002-06-06 2005-03-22 Sandia Corporation Microfabricated cylindrical ion trap
US6822225B2 (en) 2002-09-25 2004-11-23 Ut-Battelle Llc Pulsed discharge ionization source for miniature ion mobility spectrometers
US6838666B2 (en) * 2003-01-10 2005-01-04 Purdue Research Foundation Rectilinear ion trap and mass analyzer system and method
US7081623B2 (en) * 2003-09-05 2006-07-25 Lucent Technologies Inc. Wafer-based ion traps
GB0514964D0 (en) 2005-07-21 2005-08-24 Ms Horizons Ltd Mass spectrometer devices & methods of performing mass spectrometry
US6933498B1 (en) * 2004-03-16 2005-08-23 Ut-Battelle, Llc Ion trap array-based systems and methods for chemical analysis
US7514674B2 (en) * 2004-05-04 2009-04-07 The University Of North Carolina At Chapel Hill Octapole ion trap mass spectrometers and related methods
NZ553460A (en) 2004-08-02 2010-06-25 Owlstone Ltd Ion mobility spectrometer
US7217922B2 (en) * 2005-03-14 2007-05-15 Lucent Technologies Inc. Planar micro-miniature ion trap devices
US7560688B2 (en) * 2005-10-14 2009-07-14 Washington State University Mass analysis of mobility selected ion populations
JP4621744B2 (ja) 2005-11-28 2011-01-26 株式会社日立製作所 イオンガイド装置、イオン反応装置、及び質量分析装置
JP4248540B2 (ja) 2005-11-30 2009-04-02 株式会社日立ハイテクノロジーズ 質量分析装置およびこれを用いる計測システム
CN101063672A (zh) * 2006-04-29 2007-10-31 复旦大学 离子阱阵列
US7456398B2 (en) 2006-05-05 2008-11-25 Thermo Finnigan Llc Efficient detection for ion traps
TWI484529B (zh) * 2006-11-13 2015-05-11 Mks Instr Inc 離子阱質譜儀、利用其得到質譜之方法、離子阱、捕捉離子阱內之離子之方法和設備
GB0626025D0 (en) 2006-12-29 2007-02-07 Thermo Electron Bremen Gmbh Ion trap
US7847240B2 (en) 2007-06-11 2010-12-07 Dana-Farber Cancer Institute, Inc. Mass spectroscopy system and method including an excitation gate
JP4905270B2 (ja) 2007-06-29 2012-03-28 株式会社日立製作所 イオントラップ、質量分析計、イオンモビリティ分析計
US8334506B2 (en) 2007-12-10 2012-12-18 1St Detect Corporation End cap voltage control of ion traps
US7973277B2 (en) 2008-05-27 2011-07-05 1St Detect Corporation Driving a mass spectrometer ion trap or mass filter
CN102150219B (zh) 2008-07-28 2015-01-28 莱克公司 在射频场中使用网的离子操纵的方法和设备
US7772546B2 (en) 2008-09-23 2010-08-10 Ohio University Portable loeb-eiber mass spectrometer
US8101908B2 (en) 2009-04-29 2012-01-24 Thermo Finnigan Llc Multi-resolution scan
US8440963B2 (en) * 2010-04-09 2013-05-14 Battelle Memorial Institute System and process for pulsed multiple reaction monitoring
WO2011079202A1 (en) * 2009-12-23 2011-06-30 Academia Sinica Apparatuses and methods for portable mass spectrometry
FR2955261B1 (fr) * 2010-01-18 2013-03-08 Sveltus Pompe / verin pour dispositif destine a faire travailler simultanement des muscles antagonistes, comportant essentiellement un verin a eau ou autre fluide capable de travailler en traction puis en compression, dispositif correspondant comportant des moyens de contact avec le corps ou de manoeuvre, ledit dispositif et applications correspondantes en gymnastique, musculation
EP2390899B1 (en) * 2010-05-27 2012-07-04 Universität Innsbruck Apparatus and method for trapping charged particles and performing controlled interactions between them
JP5950913B2 (ja) * 2010-08-25 2016-07-13 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 有意な六重極および八重極成分を有する実質的に四重極の電場を提供するための方法およびシステム
KR101711145B1 (ko) * 2010-09-03 2017-03-13 삼성전자주식회사 휴대용 4중극자 이온트랩 질량분석기
US8581177B2 (en) * 2011-04-11 2013-11-12 Thermo Finnigan Llc High duty cycle ion storage/ion mobility separation mass spectrometer
CN103367093B (zh) 2012-03-30 2016-12-21 岛津分析技术研发(上海)有限公司 线型离子束缚装置及其阵列结构
US9373492B2 (en) 2013-03-14 2016-06-21 The University Of North Carolina At Chapel Hill Microscale mass spectrometry systems, devices and related methods
US8878127B2 (en) 2013-03-15 2014-11-04 The University Of North Carolina Of Chapel Hill Miniature charged particle trap with elongated trapping region for mass spectrometry
US9214325B2 (en) 2013-03-15 2015-12-15 1St Detect Corporation Ion trap with radial opening in ring electrode
US9711341B2 (en) 2014-06-10 2017-07-18 The University Of North Carolina At Chapel Hill Mass spectrometry systems with convective flow of buffer gas for enhanced signals and related methods
US9406492B1 (en) 2015-05-12 2016-08-02 The University Of North Carolina At Chapel Hill Electrospray ionization interface to high pressure mass spectrometry and related methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101330965A (zh) * 2005-12-13 2008-12-24 杨百翰大学 小型环形射频离子阱质量分析器
CN102884608A (zh) * 2010-01-15 2013-01-16 莱克公司 离子阱质谱仪

Also Published As

Publication number Publication date
EP2973650A1 (en) 2016-01-20
CN105190827A (zh) 2015-12-23
JP6759095B2 (ja) 2020-09-23
US11158496B2 (en) 2021-10-26
US10141178B2 (en) 2018-11-27
WO2014143101A1 (en) 2014-09-18
JP7301095B2 (ja) 2023-06-30
US9252005B2 (en) 2016-02-02
JP2019145520A (ja) 2019-08-29
US20140264001A1 (en) 2014-09-18
US20170263432A1 (en) 2017-09-14
US20190096655A1 (en) 2019-03-28
US20150122990A1 (en) 2015-05-07
JP2021168301A (ja) 2021-10-21
EP2973650A4 (en) 2016-11-02
JP7194071B2 (ja) 2022-12-21
US8878127B2 (en) 2014-11-04
CN109148255A (zh) 2019-01-04
CN105190827B (zh) 2018-08-03
US20160141168A1 (en) 2016-05-19
EP2973650B1 (en) 2019-08-28
JP2016517138A (ja) 2016-06-09
JP7600300B2 (ja) 2024-12-16
JP2023086802A (ja) 2023-06-22

Similar Documents

Publication Publication Date Title
US11158496B2 (en) Miniature charged particle trap with elongated trapping region for mass spectrometry
US12014915B2 (en) Ion traps with y-directional ion manipulation for mass spectrometry and related mass spectrometry systems and methods
US10755915B2 (en) Microscale mass spectrometry systems, devices and related methods
Kelly et al. The ion funnel: theory, implementations, and applications
AU2003297655B2 (en) Processes for designing mass separators and ion traps, methods for producing mass separators and ion traps. mass spectrometers, ion traps, and methods for analysing samples
Austin et al. Halo ion trap mass spectrometer
US20160035556A1 (en) Ion funnel for efficient transmission of low mass-to-charge ratio ions with reduced gas flow at the exit
US9711341B2 (en) Mass spectrometry systems with convective flow of buffer gas for enhanced signals and related methods
CN105719936A (zh) 利用分段式螺旋电极的多级离子引导器及有关系统和方法
EP1968100B1 (en) Ion guide chamber
Fico et al. Circular arrays of polymer-based miniature rectilinear ion traps
Schultze Advanced System Components for the Development of a Handheld Ion Trap Mass Spectrometer

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant