CN109125655A - Application of the radix euphorbiae lantu jujube side in curing psoriasis - Google Patents
Application of the radix euphorbiae lantu jujube side in curing psoriasis Download PDFInfo
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Abstract
The invention discloses a kind of new medical use of radix euphorbiae lantu jujube side, i.e. application of the radix euphorbiae lantu jujube side in curing psoriasis belongs to pharmaceutical technology field.The present invention to psoriatic by taking orally by following weight fraction into the prescription being grouped as: radix euphorbiae lantu 27-29%, jujube 55-57%, kuh-seng 4-5%, frutus cnidii 2-2.5%, gentianae macrophyllae 2-2.5%, tuber of stemona 2-2.5%, mung bean 2-2.5%, Cortex Phellodendri 1-2%, licorice 1-2%.The present invention has accomplished the pure Chinese medicine treatment of psoriasis, and drug is low in cost, and reducing psoriatic needs financial burden caused by Long-term taking medicine.And clinical test proves, in using the treatment of this prescription, 99% or more psoriatic, symptom is relieved within 8-16 weeks, 16-24 weeks symptom complete incidence graph, and rare recurrence, to achieve the purpose that eradicate psoriasis.
Description
Technical field
The present invention relates to pharmaceutical technology fields, and in particular to application of the radix euphorbiae lantu jujube side in curing psoriasis.
Background technique
Psoriasis is a kind of common chronic recurrent inflammatory dermatoses.The disease course of disease is relatively long, still cannot at present
It cures completely.As a kind of erythroderma desquamativum, patient's appearance damage is often resulted in, and seriously affects the life matter of patient
Amount is even physically and mentally healthy.End-stage disease it is also quite conceivable to damage patient joint and multiple internal organs, it is strong to the life of patient
Kang Zaocheng great threat.
Document shows that the cause of disease of psoriasis is still not clear at present, it is generally recognized that is that " itself exempts from one kind mainly by immune-mediated
Epidemic disease unbalance of system disease ".Most scholars think that the disease is that one kind as caused by the multiple-factor inheritance of patient is thin by T lymph
The immunological diseases that born of the same parents mediate, while scholars think the infection, unreasonable use that the disease may also cause because of patient's severe trauma
The reasons such as medicine, excessive Smoking And Drinking and other merging diseases cause.
Psoriasis is classified according to its Clinical symptoms, is broadly divided into vulgaris, joint type, pustule type and erythrodermic,
And 90% or more psoriasis belongs to vulgaris.Psoriasis vulgaris often has in the portions such as scalp, knee, elbow and trunk, four limbs
Position, and symmetrical feature is showed, wherein basic skin lesion, mostly based on the patch of red papules, surface attachment is silvery white
The color scales of skin that peel off, if being struck off, there will be the generations of petechial hemorrhage phenomenon.And facial skin lesion is then drop-wise wellability erythema and a fash；
Scalp skin lesion is then that apparent pencil occurs；The position skin lesions to rub such as oxter and breast are rendered as the scales of skin that peel off and reduce and seep more
Out with rotten to the corn symptom.The same psoriasis vulgaris of skin lesion situation of joint psoriasis pustulosa, but it generally first has skin lesion, closes afterwards
Symptom is saved, can also be occurred simultaneously.Any joint can be involved, and increase the incidence of joint deformity.Erythrodermic psoriasis
Clinical manifestation be mostly that whole skin flush a large amount of bran scales of skin that peel offs then occurs with the generation of swelling, at skin lesion simultaneously, in addition may be used
The generation of the constitutional symptoms such as fever can be had.Psoriasis pustulosa: it is divided into limitation or general hair.1. limitation pustular silver is considered to be worth doing
Sick skin lesion is confined to palm and vola pedis, symmetrical, and skin lesion is the pimple on the basis of erythema.2. generalized pustular psoriasis
Normal acute onset, occur rapidly differing in size on Psoriasis Vulgaris or normal skin without skin lesion yellow-white superficial without
Bacterium property pimple, dense distribution can merge, and fast and whole body can have the constitutional symptoms such as shiver with cold, high fever.Some cases have fever, head
Bitterly, arthralgia and superficial lymph knot enlargement etc. show.
Treatment for psoriasis, interleukins (IL) class drug is the hot spot researched and developed at present, such as: excellent spy's gram list
Anti-, Su Jin monoclonal antibody is used for the systemic therapy of middle severe psoriasis.There are external drug, oral drugs, bio-pharmaceutical etc. a variety of at present
Drug is approved for symptomatic treatment (Rizvi S, Chaudhari K, the Syed B A. The psoriasis of psoriasis
drugs market. Nat Rev Drug Discov, 2015,14 (11): 745-746).Light moderate psoriatic is logical
Be often used adjust genetic transcription, inhibit cell Proliferation, promote keratinocyte differentiation local topical formulation, as corticoid,
V-A acidic tazarotene, calcineurin inhibitors tacrolimus, novel vitamin D analogues Calcipotriol and by card
Moor the compound preparation of three pure and mild betamethasone dipropionate compositions.For more serious psoriatic, in addition to needing using light
Treatment will also use such as methotrexate (MTX), Acitretin acid or the oral systemic therapy drug of cyclosporine class.Phosphodiesterase-4 suppression
Preparation A Pusite is also used for treatment psoriasis.TNF antagonist Etanercept (Enbrel), infliximab (class gram) and Ah
Up to the wooden monoclonal antibody (Xiu Meile), the significant effect in the treatment of psoriasis.However, due to the morbidity of tnf inhibitor and malignant tumour
Rate rises correlation, limits the application of this kind of drug.
The application of the above drug achieves huge progress with research and development in the treatment of psoriasis, but psoriasis is suffered from
For person, biological therapy price is extremely expensive, and patient economy burden is huge, and these drugs are short-term and long-term toxic side effect is aobvious
It writes.
Present invention applicant has found in the pathogenesis of psoriasis that the infection of tulase has risen to pass in clinical observation
Important role.Preferable therapeutic effect can be reached to psoriasis in a short time by antituberculosis therapy.It follows that silver bits
The generation of disease is related with immune response caused by tubercle bacillus affection, is the delayed allergy after a kind of tuberculosis infection.This hair
Bright applicant has cured more psoriatic with tuberculosis chemotherapeutics, but the toxic side effect of tuberculosis chemotherapeutics is general
Larger, some patientss are difficult to be resistant to.
Summary of the invention
The purpose of the invention is to overcome expensive, toxic side effect existing for existing curing psoriasis drug is strong to lack
It falls into, a kind of new medical use of tuberculosis chemotherapeutics, i.e. application of the radix euphorbiae lantu jujube side in curing psoriasis is provided.
Application of the radix euphorbiae lantu jujube side of the present invention in curing psoriasis, specifically, by weight percentage, suffering to psoriasis
Person takes the prescription consisted of the following compositions: radix euphorbiae lantu 27-29%, jujube 55-57%, kuh-seng 4-5%, frutus cnidii 2-2.5%, gentianae macrophyllae 2-
2.5%, tuber of stemona 2-2.5%, mung bean 2-2.5%, Cortex Phellodendri 1-2%, licorice 1-2%.
Preferably, the prescription consisted of the following compositions: radix euphorbiae lantu 1450-1550g, jujube 2900- are taken to psoriatic
3100g, kuh-seng 230-250g, frutus cnidii 110-130g, gentianae macrophyllae 110-130g, tuber of stemona 110-130g, mung bean 110-130g, Cortex Phellodendri
75-85g, licorice 75-85g.
The prescription the preparation method comprises the following steps: the radix euphorbiae lantu of prescription amount is put into irony steamer, pure water is added, bundle is had small
The jujube in hole is placed on food steamer, then food steamer is placed on irony steamer, and food steamer bottom and the water surface keep 20cm or more, is abandoned after steaming 2h
Radix euphorbiae lantu cools jujube, is mixed thoroughly with white wine, and sealing is placed 4d and can be taken；Remaining drug is merged by prescription to be crushed as fine powder.
The instructions of taking of above-mentioned radix euphorbiae lantu jujube side are as follows: jujube day dose by 25g, such as without side-effects, increment weekly
5g, daily at most 35g is the upper limit；Other drugs fine powder twice daily, take after mixing it with water by each 6g warm water.
Prescription analysis:
Radix euphorbiae lantu is monarch drug in a prescription in radix euphorbiae lantu jujube side, and Chinese Medicine net is described below radix euphorbiae lantu: radix euphorbiae lantu is Isolated From Thymelaeaceae Species winter daphne wolf
The root of poison or euphorbia plant euphorbia fischeriana, euphorbia ebiacteolata Hayata.Spring, autumn excavation, cauline leaf, silt are removed, is dried.Its toxicity is very big, accidentally
Less serious case shows as that dizzy, out of strength, Nausea and vomiting, foot accent is light, bottleneck throat burning heat sensation, salivates and has a stomach upset after food, and severe one is complete
Body is out of strength, perspires, difficult, stupor of taking a step, twitch, vomits frequent, final faint from fear and die.In ancient prescription the efficacy of drugs of radix euphorbiae lantu compared with
More, treating tuberculosis effect therein is particularly important, can control the tuberculosis such as lymph node, skin, bone, epididymis.
Kuh-seng, the tuber of stemona, gentianae macrophyllae, Cortex Phellodendri and frutus cnidii are ministerial drug in side.Kuh-seng clearing heat and promoting diuresis, antibacterial anti-inflammatory, stomach invigorating expelling parasite can be controlled
Treat the diseases such as pruitus；The gentle lung qi of the tuber of stemona, inducing diaphoresis of radiating enter lung channel, and solution fur is antipruritic；Gentianae macrophyllae wind-damp dispelling, clearing away damp-heat, pharmacological property
Embellish but not dry, no matter cold-dampness, damp and hot, bi Zheng is newly long, can all apply.Modern medical research has found that gentianae macrophyllae has apparent anti-inflammatory work
With gentianin has antianaphylaxis shock and antihistamine effect；Cortex Phellodendri heat-clearing and damp-drying drug, purging intense heat, removing toxic substances；Frutus cnidii eliminating dampness, dispels
Wind, desinsection, warming kidney and enhancing body.
Jujube is adjutant in side.Introduction in " book on Chinese herbal medicine is newly organized " to jujube are as follows: logical nine orifices and hundred medicines, feeding lung stomach, QI invigorating,
Moistening herat and lung is promoted the production of body fluid, and all warps, tonifying five zang organs are helped.The effect of Zhang Zhongjing is by jujube and euphorbia fischeriana collocation, exactly " jujube and hundred medicines "
Important representative.Euphorbia fischeriana property is high strong, easily hurts healthy tendency, and jujube shares therewith, there is the effect of righting is timid evil.During steaming
Jujube absorbs the effective component in radix euphorbiae lantu, plays the role of carrier, while the toxicity of radix euphorbiae lantu also weakens significantly.
Radix Glycyrrhizae and mung bean are to make medicine in side.Chinese medicine thinks that Radix Glycyrrhizae has the effect of coordinating the drug actions of a prescription, reaches optimum therapeuticing effect.It is existing
For the synthesising preparation of medical discovery licorice, " compound ammonium glycyrrhizinato injection " can preferably treat eczema, nettle rash,
The anaphylactias such as rheumatism, allergic asthma；And it also found that the anti-inflammatory effect of Radix Glycyrrhizae may be with its change with steroids
It is related to learn structure.So Radix Glycyrrhizae acts also as the role of ministerial drug treatment in this side from Traditional Chinese Medicine and modern medicine；Mung bean
Hundred poison can be solved, the excretion of internal poisonous substance can be helped, promote the eubolism of body.
Relative to existing curing psoriasis drug, technical solution of the present invention is had the advantages that
1, in prescription of the present invention radix euphorbiae lantu and jujube compatibility be Chinese medicine treating tuberculosis the prescription that effects a permanent cure, add other treating both manifestation and root cause of disease medicines
Object can increase the curative effect and compliance of curing psoriasis, reach better therapeutic effect.The present invention goes out from the cause of disease of psoriasis
Hair, revolutionizes the treatment concept of original curing psoriasis drug, has accomplished the pure Chinese medicine treatment of psoriasis, and drug is at low cost
Honest and clean, reducing psoriatic needs financial burden caused by Long-term taking medicine.
2, prescription of the present invention can treat various types of psoriasis, and can adjust medication by the obstinate degree of psoriasis
Dosage and time reduce the toxic side effect of routine administration time and drug.Clinical test proves, in using the treatment of this prescription,
99% or more psoriatic, symptom is relieved within 8-16 weeks, 16-24 weeks symptom complete incidence graph, and rare recurrence, to reach
The purpose of radical cure psoriasis is arrived.
Detailed description of the invention
Fig. 1 is the pretherapy and post-treatment right abdomen skin characteristic figure of patient in case one；Fig. 1 (a) is before treating, and Fig. 1 (b) is to control
After treatment；
Fig. 2 is that patient treats preceding right abdomen dermal pathology figure in case one；
Fig. 3 is that patient treats antedorsal skin characteristic figure in case two；Fig. 3 (a) is before treating, and Fig. 3 (b) is after treating；
Fig. 4 is that patient treats antedorsal dermal pathology figure in case two；
Fig. 5 is that patient treats antedorsal skin characteristic figure in case three；Fig. 5 (a) is before treating, and Fig. 5 (b) is after treating；
Fig. 6 is that patient treats antedorsal dermal pathology figure in case three；
Fig. 7 is that patient treats preceding calf skin characteristic figure in case four；Fig. 7 (a) is before treating, and Fig. 7 (b) is after treating；
Fig. 8 is that patient treats front right calf dermal pathology figure in case four.
Specific embodiment
Application method of the radix euphorbiae lantu jujube side of the present invention in curing psoriasis is made further specifically below with reference to case
It is bright.
One, pathologic finding process:
Step 1: drawing materials and fixing:
(10% formalin, Bouin in the fixer for taking flesh tissue block (thickness is no more than 0.5 centimetre) investment to prepare in advance
Family name's fixer), make the protein denaturation solidification of tissue, cell, cell self-dissolving after death or the decomposition of bacterium is prevented, to keep
The original morphosis of cell.
Step 2: dehydration is transparent:
Make dehydrating agent with low concentration to alcohol in high concentration, gradually sloughs the moisture in tissue block.Tissue block is placed in again and was both dissolved in
Alcohol, and it is dissolved in transparent in the clarifier dimethylbenzene of paraffin, the alcohol in tissue block is replaced out with dimethylbenzene.
Step 3: waxdip embeds:
Transparent tissue block is placed in the paraffin dissolved, the heat preservation of dewaxing case is put into.After paraffin is completely immersed in tissue block
It is embedded: first preparing container (as folded a small paper box), pour into the paraffin dissolved, clamping has been impregnated with the group of paraffin rapidly
It knits block to be put into wherein, cooled and solidified is at lump.
Step 4: slice and patch:
Embedded wax stone is fixed on slicer, the thin slice of 5-8 μ m-thick is cut into.The thin slice cut often fold, will be put into
It plates, then is attached on glass slide in the water of heating, put in 45 DEG C of insulating boxs and dry.
Step 5: dewaxing:
It is dyed with HE, to increase the heterochromia of tissue cellularity each section, is conducive to observation.Hematoxylin (Hematoxylin,
HE) it is a kind of basic dye, nucleus and intracellular ribosomes can be dyed bluish violet, had by the structure of basic dyeing
Basophilla.Yihong (Eosin, E) is a kind of acid dyes, cytoplasm can be dyed to red or pale red, by acid dyeing
Structure have acidophilia.Before dyeing, the paraffin in slice must be sloughed with dimethylbenzene, then via high concentration to low-concentration ethanol,
Finally enter distilled water, so that it may dye.
Step 6: dyeing:
HE dyeing course is:
(1) it the slice after distilled water will have been entered has been put into hematoxylin aqueous solution to dye several minutes.
(2) color separation in sour water and ammonium hydroxide, each several seconds.
(3) flowing water enters distilled water a moment after rinsing 1 hour.
(4) 70% and 90% are dehydrated each 10 minutes in alcohol.
(5) enter alcohol eosin stains liquid to dye 2-3 minutes.
Step 7: dehydration is transparent:
Slice after dyeing is dehydrated through dehydrated alcohol, then through dimethylbenzene makes to be sliced transparent.
Step 8: sealing:
Transparent slice is dripped into upper canada balsam, covered sealing.After natural gum is slightly dry, mark writing paper is sticked, will be sliced
Sample is placed in microscopically observation.
Two, specific case
Case one
Bei Xinru, male, 48 years old, weight 65kg.Present illness history: there is erythema, have a large amount of furfurs, incrustation in patient's trunk, four limbs, have light
The itch of degree, without other obvious subjective symptoms 5 years.
Physical examination: throughout about 0.4 × 0.4cm size erythema, papule, boundary is clear, has volume furfur, after striking off for trunk, four limbs
Easy bleeding, part are formed a scab.Patient's right abdomen cutaneous lesions feature is as shown in Fig. 1 (a).
Pathological diagnosis: right abdomen skin, as shown in Fig. 2, epidermal hyperkeratosis is with parakeratosis, epidermal hyperplasia, skin foot
Broadening downward, inflammatory cell is dispersed in infiltration, substrate pigment major part depigmentation in papillary layer of corium；Papilla is shown in bites melanocyte on a small quantity
Cell meets psoriasis vulgaris performance.
Therapeutic regimen:
Radix euphorbiae lantu jujube prescription: radix euphorbiae lantu 1500g, jujube 3000g, kuh-seng 240g, frutus cnidii 120g, gentianae macrophyllae 120g, tuber of stemona 120g are green
Beans 120g, Cortex Phellodendri 80g, licorice 80g.
The prescription the preparation method comprises the following steps: the radix euphorbiae lantu of prescription amount is put into irony steamer, 8L pure water is added, bundle is had
The jujube of aperture is placed on food steamer, then food steamer is placed on irony steamer, and food steamer bottom and the water surface keep 20cm or more, after steaming 2h
Radix euphorbiae lantu is abandoned, jujube is cooled, is mixed thoroughly with white wine, sealing is placed 4d and can be taken；Remaining drug is merged by prescription to be crushed as fine powder.
Instructions of taking are as follows: jujube day dose by 25g, increment 5g weekly, daily at most 35g are the upper limit (because of market
The jujube difference in size of upper sale is larger, therefore using every piece of jujube 5g as standard)；Other drugs fine powder twice daily, each 6g temperature
Mixing in water for oral taking.
Prognosis: the cutaneous lesions of 14 weeks or so patient's the pasts are relieved, and are fullyed recover from an illness substantially in 20 weeks or so cutaneous lesions
More.As shown in Fig. 1 (b), skin lesion is existing all to subside the same area skin state of patient, and skin has become smooth after taking medicine 28 weeks.
It is discontinued, does not recur after (calculating the time from the day of medication) continuous medication year and a day within 1 year so far.
Case two
Li Xiaochun: female, 35 years old, 68 Kg of weight.Present illness history: whole body plays erythema, furfur with itch 7 years.After two years ago oral traditional Chinese medicine
Deflorescence is recurred again after drinking, other various therapeutic effects are bad.Physical examination: scalp, face, neck, shirtfront, back, four
Limb is shown in that more erythema diffuses in flakes, has furfur, incrustation, has slight itch, without other obvious subjective symptoms.Patient's skin of back
Lesion characteristics are as shown in Fig. 3 (a).
Pathological diagnosis: skin of back, as shown in figure 4, epidermal hyperkeratosis companion's parakeratosis, epidermal hyperplasia, skin foot are broadening
Downward, acanthosis, prickle cell's balloon sample becomes or slight sponge oedema, sees multiple microabscess in angling object, in papillary layer of corium
Inflammatory cell is dispersed in infiltration, substrate pigment major part depigmentation；Papilla is shown in a small amount of melanophage, meets psoriasis performance.
Therapeutic regimen:
Radix euphorbiae lantu jujube prescription: radix euphorbiae lantu 1400g, jujube 3100g, kuh-seng 230g, frutus cnidii 110g, gentianae macrophyllae 110g, tuber of stemona 110g are green
Beans 110g, Cortex Phellodendri 90g, licorice 90g.
The preparation method and instructions of taking of the prescription are the same as case one.
Prognosis: the cutaneous lesions of 12 weeks or so patient's the pasts are relieved, and are fullyed recover from an illness substantially in 22 weeks or so cutaneous lesions
More.The same area skin state of patient is as shown in Figure 3 (b) after taking medicine 22 weeks, and skin lesion is existing all to subside, and skin has become smooth.
It is discontinued, does not recur after (calculating the time from the day of medication) continuous medication year and a day within 2 years so far.
Case three
Zhang Junlin, male, 28 years old, weight 67Kg, present illness history: patient without obvious inducement occur trunk, four limbs erythema, partially have it is a large amount of
Silver color furfur, incrustation, there is slight itch, obvious consciously uncomfortable without other, no cough and fever.
Physical examination: trunk, four limbs are throughout about 0.5 × 0.4cm size erythema, papule, and part is continuous in blocks, and boundary is clear, has more
Furfur is measured, rear easy bleeding is struck off.Patient's skin of back lesion characteristics are as shown in Fig. 5 (a).
Pathological diagnosis: skin of back, as shown in fig. 6, epidermal hyperkeratosis companion's parakeratosis, epidermal hyperplasia, skin foot are broadening
Downward, acanthosis, prickle cell's balloon sample becomes or slight sponge oedema, and inflammatory cell is dispersed in infiltration, substrate in papillary layer of corium
Pigment major part depigmentation；Papilla is shown in a small amount of melanophage, and multiple microabscess are seen in angling object, meet psoriasis vulgaris
Performance.
Therapeutic regimen:
Radix euphorbiae lantu jujube prescription: radix euphorbiae lantu 1600g, jujube 3100g, kuh-seng 250g, frutus cnidii 120g, gentianae macrophyllae 120g, tuber of stemona 120g are green
Beans 120g, Cortex Phellodendri 100g, licorice 100g.
The preparation method and instructions of taking of the prescription are the same as case one.
Prognosis: the cutaneous lesions of 15 weeks or so patient's the pasts are relieved, and are fullyed recover from an illness substantially in 24 weeks or so cutaneous lesions
More.As shown in Fig. 5 (b), skin lesion is existing all to subside the same area skin state of patient, and skin has become smooth after taking medicine 28 weeks.
It is discontinued, does not recur after (calculating the time from the day of medication) continuous medication year and a day within 1 year so far.
Case four
Text of an annotated book intelligence, male, 48 years old, weight 59Kg, present illness history: there is erythema, take off in part trunk, four limbs after readme was mostly drunk before 6 years
Consider to be worth doing symptom, after alleviated by Chinese traditional treatment skin lesion.There is above-mentioned symptom again in patient skin over the past two years, take Chinese medicine and
It is not relieved after other drugs, lesion, which has, aggravates expansion trend, and physical examination: entire patient's rubefaction, oedema are obvious, with big
The furfur of amount has slight itch, there is the constitutional symptoms such as fever, chilly, loss of appetite.
Physical examination: trunk, limbs skin be rubescent, furfur, and part scurf major diameter is more than 1cm.Patient's right leg portion cutaneous lesions
Feature is as shown in Figure 7 (a).
Pathological diagnosis: right leg portion skin, as shown in figure 8, epidermal hyperkeratosis is with parakeratosis, epidermal hyperplasia, skin foot
Broadening downward, prickle cell's balloon sample becomes or slight sponge oedema, and inflammatory cell infiltrates extensively in papillary layer of corium, and substrate pigment is big
Part depigmentation；Papilla is shown in a small amount of melanophage, and multiple microabscess are seen in angling object, meets erythrodermic silver in conjunction with clinic
Bits disease performance.
Therapeutic regimen:
Radix euphorbiae lantu jujube prescription: radix euphorbiae lantu 1500g, jujube 2900g, kuh-seng 240g, frutus cnidii 110g, gentianae macrophyllae 110g, tuber of stemona 110g are green
Beans 110g, Cortex Phellodendri 90g, licorice 90g.
The preparation method and instructions of taking of the prescription are the same as case one.
Prognosis: the cutaneous lesions of 15 weeks or so patient's the pasts are relieved, and are fullyed recover from an illness substantially in 24 weeks or so cutaneous lesions
More.The same area skin state of patient is as shown in Figure 7 (b) after taking medicine 24 weeks, and skin lesion is existing all to subside, and skin has become smooth.
It is discontinued, does not recur after (calculating the time from the day of medication) continuous medication year and a day within 2 years so far.
Claims (3)
1. application of the radix euphorbiae lantu jujube side in curing psoriasis, characterized in that by weight percentage, taken to psoriatic
The prescription consisted of the following compositions: radix euphorbiae lantu 27-29%, jujube 55-57%, kuh-seng 4-5%, frutus cnidii 2-2.5%, gentianae macrophyllae 2-2.5%,
Tuber of stemona 2-2.5%, mung bean 2-2.5%, Cortex Phellodendri 1-2%, licorice 1-2%；
The prescription the preparation method comprises the following steps: the radix euphorbiae lantu of prescription amount is put into irony steamer, pure water is added, will prick foraminate
Jujube is placed on food steamer, then food steamer is placed on irony steamer, and food steamer bottom and the water surface keep 20cm or more, abandons wolf after steaming 2h
Poison cools jujube, is mixed thoroughly with white wine, and sealing is placed 4d and can be taken；Remaining drug is merged by prescription to be crushed as fine powder.
2. application of the radix euphorbiae lantu jujube side as described in claim 1 in curing psoriasis, characterized in that the radix euphorbiae lantu jujube side
It consists of the following compositions: radix euphorbiae lantu 1450-1550g, jujube 2900-3100g, kuh-seng 230-250g, frutus cnidii 110-130g, gentianae macrophyllae
110-130g, tuber of stemona 110-130g, mung bean 110-130g, Cortex Phellodendri 75-85g, licorice 75-85g.
3. application of the radix euphorbiae lantu jujube side as claimed in claim 1 or 2 in curing psoriasis, characterized in that the radix euphorbiae lantu is big
The instructions of taking of jujube side are as follows: jujube day dose by 25g, such as without side-effects, increment 5g weekly, daily at most 35g are upper
Limit；Other drugs fine powder twice daily, take after mixing it with water by each 6g warm water.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1226440A (en) * | 1998-12-06 | 1999-08-25 | 牛余森 | Medicine for psoriasis and preparing method thereof |
| CN1546121A (en) * | 2003-11-28 | 2004-11-17 | 姚会伶 | Medicine for treating psoriasis and its preparation |
| CN1772100A (en) * | 2005-10-26 | 2006-05-17 | 邢继华 | Medicine for treating psoriasis and its prepn |
| CN107582612A (en) * | 2017-09-12 | 2018-01-16 | 福建省尤溪仙锦药业有限公司 | A kind of concocting method of the Radix Astragali |
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2018
- 2018-10-30 CN CN201811279389.2A patent/CN109125655A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1226440A (en) * | 1998-12-06 | 1999-08-25 | 牛余森 | Medicine for psoriasis and preparing method thereof |
| CN1546121A (en) * | 2003-11-28 | 2004-11-17 | 姚会伶 | Medicine for treating psoriasis and its preparation |
| CN1772100A (en) * | 2005-10-26 | 2006-05-17 | 邢继华 | Medicine for treating psoriasis and its prepn |
| CN107582612A (en) * | 2017-09-12 | 2018-01-16 | 福建省尤溪仙锦药业有限公司 | A kind of concocting method of the Radix Astragali |
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| 何昌善等: "《临症用药纲目》", 31 August 2017, 中国医药科技出版社 * |
| 戴明等: "复方苦参止痒霜治疗湿疹的实验研究", 《中国中西医结合皮肤性病学杂志》 * |
| 李敏: "《图解妙方大全》", 31 January 2018, 中国古籍出版社 * |
| 田风鸣等: "《中国奇方全书》", 31 January 2017, 科学技术文献出版社 * |
| 郭玉波: "复方狼毒胶囊治疗银屑病 ", 《四川中医》 * |
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