CN102688430A - Traditional Chinese medicine composition for treating pig eczema, feed, as well as preparation method and application of traditional Chinese composition - Google Patents
Traditional Chinese medicine composition for treating pig eczema, feed, as well as preparation method and application of traditional Chinese composition Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating pig eczema, which comprises rhizoma anemarrhenae, dandelion, Chinese lizardtail rhizome or herb, climbing groundsel herb, cocklebur fruit, gentian, golden larch bark, garlic, radix stemonae, cortex dictamni, belvedere fruit, wild pepper, sophora flavescens, borneol, rhizoma bletillae, astragalus, bighead atractylodes rhizome, acanthopanax root and liquorice. The traditional Chinese medicine composition and feed are used for treating the pig eczema, and have the advantages of being high in cure rate, rapid in taking effect, free from toxic and side effects, hard in generation of drug resistance, free from drug residue and the like.
Description
Technical field
The present invention relates to technical field of animal, relate in particular to a kind of feedstuff that contains the Chinese medicine composition that is useful on treatment pig eczema and preparation method thereof.
Background technology
Eczema is one of common disease of pig, and various ages and sex all can take place, and especially with young pig easy infection, pilosity is born in overcast and rainy cold season.Pig eczema can be divided into acute, subacute, chronic 3 kinds according to course of disease length, also has that intenseness of heat is wet, wet contains heat or damp and hot disease such as lay equal stress on.
The general acute eczema of acute eczema is prone to send out with growing and fattening pigs, feeder pig and piglet, rarely in sow.Morbidity rapidly, the course of disease 15～20 days, reach month surplus individually.During morbidity; Pi Wen is higher; Erubescence the grain of rice appearance punctation that quantity does not wait occurs earlier, after 3～5 days on facial area and basal part of the ear skin; Also occur in succession on neck, breast, abdomen both sides and strand inboard (minority is at whole body) skin, have to mix on the minority piglet pars affecta skin pisiformis pimple, vesicle and pustule to occur; Sick pig pruritus is uneasy, wipes everywhere and rubs.After rash piece, vesicle and pustule are frayed, flow out blood sample mucus or pus, the back forms yellow or grey black crust.Along with the prolongation of the course of disease, sick pig pruritus is uneasy, wipes everywhere and rubs.After rash piece, vesicle and pustule are frayed, flow out blood sample mucus or pus, the back forms yellow or grey black crust.Along with the prolongation of the course of disease, sick pig down in spirits, inappetence is day by day become thin, by the hair loss of gloss.Urging promptly appears breathing in piglet that has and feeder pig at the initial stage of a disease, and fervescence reaches 40 ℃.
The slight flushing of subacute eczema skin thickens, and local dark red mottle and little pimple have pruritus; Chronic eczema is more common in malnutrition, thin and weak sow or the feeder pig of body.The course of disease does not wait for 1 ~ February, and what have reaches March.The course of disease shows similar acute eczema, but nonsystemic reaction.Thereafter present tired mind, the thin hair of body is contrary; Pars affecta skin depilation, coarse, thicken hardening, even furfur appearance black crust appears, black fat-like tongue appears in the sick pig affected part that has, viscous is greasy, it is hard to bear very to itch, continually pruritus.Chronic eczema pachylosis thickening, boundary is clear, wraps dark violetly, and gauffer is arranged, and pruritus is arranged, and erosion, suppuration kitchen range and crust are arranged.
After pig only suffers from eczema, other disease of Chang Bingfa or secondary, if concurrent with piglet pujos blancos, normal more back is bad, weight person causes full nest piglet dead; After the secondary staphylococcus, local infection often appears, and rotten to the corn and suppurate, and send foul odour, cause at last that the pig body is become thin, weak, dehydration and dead; After eczema takes place in piglet, if face, ear edema generally eyelid swelled can appear, in the secondary infection edema disease about 1 week; Appetite is useless exhausted, and reaction is responsive to external world, nervous symptoms occurs; Walking is waved, instability of gait, and ground for sleeping in does not rise; Extremity are made swimming shape paddling, call hoarse, dyspnea and extremely.
In addition, primary disease can cause the inappetence of pig, often causes the slow or stagnation formation cad pig of growth promoter, thereby causes bigger harm to raising pigs.
The pathology of pig eczema mainly is under hot weather periods of direct sunlight, skin surface telangiectasis, hyperemia, and permeability increases, and serosity oozes out, and forms eczema erythematosum.Since inflammatory stimulus, dermal papilla layer generation serosity and cellular infiltration, nipple swelling forms lesser tubercle, and outstanding skin surface is claimed papular eczema.Because tissue fluid is flowed to horny layer, and inflammatory exudate increases, and under the top layer, accumulates in a large number, forms blister property eczema.When suppuration bacterium and a large amount of leukocyte get in the blister, suppurate, form pus bubble property eczema.Behind blister or the pus follicular rupture, present scarlet rotten to the corn face, tissue fluid is oozed out from rotten to the corn face, and drying is solidified gradually, forms incrustation property eczema.
Modern medicine thinks that eczema often sends out in the individuality with allergic diathesis; All individualities that allergic diathesis is arranged are to the various sensitizers in inside and outside; Like the protein in the feedstuff, some chemical drugs, the excretory toxin of Enterozoa all anaphylaxis can take place, also relevant sometimes with delayed ischemic neurological deficits, pathobolism.At large-scale pig farm, pig house is unhygienic, darkness is moist, skin is unclean, sting, chemical substance stimulation, chronic digestible tract disease, metabolic disturbance, dysendocrisiasis, vitamin deficiency etc. all can cause pig eczema generation and development.
The natural Chinese medicinal herb prescription not only can effectively prevent and treat the generation of eczema, and has the antibiotic irreplaceable function, and therefore, people begin to study energetically the application of Chinese herbal medicine in the pig eczema treatment.
From the angle of the traditional Chinese medical science, wet is a kind of deep, and greasy stagnant YIN pathogen is sick easy to be touching, and sick heresy is just defended at table, if timely Xuanhua table is wet, the heat clearing away spleen invigorating just can be gone out by heresy; Ruo Biaowei loses and to control, and changes gas battalion over to, in pathogenic factor will the change of disease be gone into, and Golden Mirror of Medicine cloud: " pruritus is immoderate for living skin ulcer all over, millet in shape, fat water logging excessive fur in Tianjin when scratching brokenly ".So be referred to as " eczema of lower limb ", " acute eczema " etc.Eczema is to be accumulate due to the resistance skin by rheumatic fever, during treatment when distinguishing that wind is many, overabundant heat, executing respectively more than wet etc. and control.Morbidity speed, the scorching hot redness of skin, existing large stretch of erythema, blood rash, vesicle, sepage is many.
Adopt Chinese herbal treatment pig eczema can strengthen the immunologic function of poultry; Improve its premunition; Can antibacterial anthelmintic antiviral; Chinese herbal medicine additive has multiple nutritional components and active substance-have concurrently nutrition and medicament dual property, and not only preventable disease was cured the disease but also can be improved fertility performance, and Chinese herbal medicine also has and improves animal body anti-stress and the effect that adapts to the adverse circumstances influence.
Summary of the invention
Technical problem to be solved by this invention is according to theory of Chinese medical science; Converge to the Therapeutic Principle with heat-clearing and toxic substances removing, dispelling wind for relieving itching, parasite killing; A kind of novel being used to Chinese medicine composition of treating pig eczema and the feedstuff that contains said Chinese medicine composition composition are provided, adopt this Chinese medicine composition and feedstuff treatment pig eczema to have cure rate height, instant effect, have no side effect; Be difficult for producing drug resistance, be difficult for causing the advantage of aspects such as drug residue.
In order to solve the problems of the technologies described above; The invention provides a kind of Chinese medicine composition that is used to treat pig eczema, it comprises: the Rhizoma Anemarrhenae, Herba Taraxaci, Rhizoma Saururi (Herba Saururi), Herba Senecionis Scandentis, Fructus Xanthii, Radix Gentianae, Cortex Pseudolaricis, Bulbus Allii, the Radix Stemonae, Cortex Dictamni, the Fructus Kochiae, Pericarpium Zanthoxyli, Radix Sophorae Flavescentis, Borneolum Syntheticum, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Caulis Acanthopanacis Senticosi and Radix Glycyrrhizae.
Wherein, The said Chinese medicine composition that is used to treat pig eczema, the ratio of weight and number of various components can be: the Rhizoma Anemarrhenae 80～90 weight portions, Herba Taraxaci 40～50 weight portions, Rhizoma Saururi (Herba Saururi) 55～65 weight portions, Herba Senecionis Scandentis 45～55 weight portions, Fructus Xanthii 30～40 weight portions, Radix Gentianae 20～30 weight portions, Cortex Pseudolaricis 15～25 weight portions, Bulbus Allii 20～30 weight portions, the Radix Stemonae 20～30 weight portions, Cortex Dictamni 15～25 weight portions, the Fructus Kochiae 10～20 weight portions, Pericarpium Zanthoxyli 20～30 weight portions, Radix Sophorae Flavescentis 15～25 weight portions, Borneolum Syntheticum 10～20 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 10～20 weight portions, the Radix Astragali 20～30 weight portions, the Rhizoma Atractylodis Macrocephalae 15～25 weight portions, Radix Et Caulis Acanthopanacis Senticosi 10～20 weight portions, Radix Glycyrrhizae 30～40 weight portions.
Wherein, The said Chinese medicine composition that is used to treat pig eczema, the ratio of weight and number of various components also can be: the Rhizoma Anemarrhenae 85～90 weight portions, Herba Taraxaci 45～50 weight portions, Rhizoma Saururi (Herba Saururi) 60～65 weight portions, Herba Senecionis Scandentis 50～55 weight portions, Fructus Xanthii 35～40 weight portions, Radix Gentianae 25～30 weight portions, Cortex Pseudolaricis 20～25 weight portions, Bulbus Allii 25～30 weight portions, the Radix Stemonae 25～30 weight portions, Cortex Dictamni 20～25 weight portions, the Fructus Kochiae 15～20 weight portions, Pericarpium Zanthoxyli 25～30 weight portions, Radix Sophorae Flavescentis 20～25 weight portions, Borneolum Syntheticum 15～20 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 15～20 weight portions, the Radix Astragali 25～30 weight portions, the Rhizoma Atractylodis Macrocephalae 20～25 weight portions, Radix Et Caulis Acanthopanacis Senticosi 15～20 weight portions, Radix Glycyrrhizae 35～40 weight portions.
Wherein, The said Chinese medicine composition that is used to treat pig eczema, the ratio of weight and number of various components also can be: the Rhizoma Anemarrhenae 85 weight portions, Herba Taraxaci 45 weight portions, Rhizoma Saururi (Herba Saururi) 60 weight portions, Herba Senecionis Scandentis 50 weight portions, Fructus Xanthii 35 weight portions, Radix Gentianae 25 weight portions, Cortex Pseudolaricis 20 weight portions, Bulbus Allii 25 weight portions, the Radix Stemonae 25 weight portions, Cortex Dictamni 20 weight portions, the Fructus Kochiae 15 weight portions, Pericarpium Zanthoxyli 25 weight portions, Radix Sophorae Flavescentis 20 weight portions, Borneolum Syntheticum 15 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 15 weight portions, the Radix Astragali 25 weight portions, the Rhizoma Atractylodis Macrocephalae 20 weight portions, Radix Et Caulis Acanthopanacis Senticosi 15 weight portions, Radix Glycyrrhizae 35 weight portions.
The present invention also provides the above-mentioned method for preparing that is used to treat the Chinese medicine composition of pig eczema, and it comprises:
The first step with each the component proportional mixing in the said Chinese medicine composition, is ground into 100 orders～200 purpose powder; Adding, decocted 30 minutes～1 hour under 90 ℃～100 ℃ temperature with respect to the water of 3～5 times of mixture qualities; Decoction liquor is filtered, and obtains first filtrate and filtering residue;
In second step, the filtering residue that the first step is obtained adds the water with respect to 1～3 times of first step mixture quality, under 90 ℃～100 ℃ temperature, decocts 30 minutes～1 hour, and decoction liquor is filtered, and obtains second filtrate;
The 3rd step merged first filtrate and second filtrate, obtained decoction liquor.
The present invention also provides a kind of feedstuff, comprises in the said feedstuff that feed vector and above-mentioned Chinese medicine composition are as additive.
Wherein, the percentage by weight of each component does in the said feedstuff, feed vector 50%～80%, the additive 6%～8% of said Chinese medicine composition.
The present invention also provides the method for preparing of above-mentioned feedstuff, and it comprises:
The first step with each the component proportional mixing in the said Chinese medicine composition, is ground into 100 orders～200 purpose powder; Adding, decocted 30 minutes～1 hour under 90 ℃～100 ℃ temperature with respect to the water of 3～5 times of mixture qualities; Decoction liquor is filtered, and obtains first filtrate and filtering residue;
In second step, the filtering residue that the first step is obtained adds the water with respect to 1～3 times of first step mixture quality, under 90 ℃～100 ℃ temperature, decocts 30 minutes～1 hour, and decoction liquor is filtered, and obtains second filtrate;
The 3rd step merged first filtrate and second filtrate, and concentrating under reduced pressure removes and desolvates; Obtain and get dry extract, it is dry that dried cream is put into spray dryer, guarantees that EAT is at 170 ℃～190 ℃; 60 ℃～80 ℃ of leaving air temps are ground into 200 orders～400 orders subsequently, obtain the Chinese medicine composition powder;
The 4th step; Feed vector is ground into 100 orders～200 purpose powder,, pours in the granulating disc that places heeling condition with the Chinese medicine composition powder mixes that the 3rd step obtained; Open granulating disc and make its rotation; Mixture in granulating disc evenly sprays vaporific high fructose syrup 20% concentration water diluent simultaneously, and the weight of said high fructose syrup water diluent is 1/5～1/10 of said mixture quality, and the rotating speed of granulating disc is 50 rev/mins; Preparation time is 15 minutes, is prepared into diameter and is 1 millimeter spherical particle feedstuff;
In the 5th step, with the spherical particle feedstuff that the 4th step obtained, the stand is put on the mesh-belt drier with the portable rustless steel guipure of multilamellar, and heat drying 10 minutes, the import pathogenic wind-warm of heating degree are 150 degree, and outlet pathogenic wind-warm degree is 80 degree, obtains exsiccant feed granules.
Food or medicine that the present invention also provides the pig feed that is used to treat pig eczema to use, said food or medicine comprise above-mentioned Chinese medicine composition.
The present invention also provides above-mentioned Chinese medicine composition to treat the food of pig eczema or the application in the medicine in preparation.
Beneficial effect of the present invention:
This traditional Chinese medicine composition for treating pig eczema provided by the invention has cure rate height, instant effect, has no side effect, and is difficult for producing drug resistance, is difficult for causing the advantage of aspects such as drug residue.
The specific embodiment
The invention provides a kind of Chinese medicine composition that is used to treat pig eczema, it comprises: the Rhizoma Anemarrhenae, Herba Taraxaci, Rhizoma Saururi (Herba Saururi), Herba Senecionis Scandentis, Fructus Xanthii, Radix Gentianae, Cortex Pseudolaricis, Bulbus Allii, the Radix Stemonae, Cortex Dictamni, the Fructus Kochiae, Pericarpium Zanthoxyli, Radix Sophorae Flavescentis, Borneolum Syntheticum, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Caulis Acanthopanacis Senticosi and Radix Glycyrrhizae.
Said Chinese medicine composition preferably only is made up of said components.
In the side, the Rhizoma Anemarrhenae, Herba Taraxaci, Rhizoma Saururi (Herba Saururi), Herba Senecionis Scandentis, Fructus Xanthii, Radix Gentianae heat-clearing and toxic substances removing, Cortex Pseudolaricis, Bulbus Allii, Radix Sophorae Flavescentis pesticide and disinfectant; The Radix Stemonae, Cortex Dictamni, the Fructus Kochiae, Pericarpium Zanthoxyli, Radix Sophorae Flavescentis dispelling wind for relieving itching, Borneolum Syntheticum anti-inflammatory analgetic, Pseudobulbus Bletillae (Rhizoma Bletillae) detumescence and promoting granulation; The Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Caulis Acanthopanacis Senticosi invigorating spleen to remove dampness; The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, all medicines share, and play heat-clearing and toxic substances removing, dispelling wind for relieving itching, parasite killing astringent effect altogether.
The said Chinese medicine composition that is used to treat pig eczema, the ratio of weight and number of various components can be preferably: the Rhizoma Anemarrhenae 80～90 weight portions, Herba Taraxaci 40～50 weight portions, Rhizoma Saururi (Herba Saururi) 55～65 weight portions, Herba Senecionis Scandentis 45～55 weight portions, Fructus Xanthii 30～40 weight portions, Radix Gentianae 20～30 weight portions, Cortex Pseudolaricis 15～25 weight portions, Bulbus Allii 20～30 weight portions, the Radix Stemonae 20～30 weight portions, Cortex Dictamni 15～25 weight portions, the Fructus Kochiae 10～20 weight portions, Pericarpium Zanthoxyli 20～30 weight portions, Radix Sophorae Flavescentis 15～25 weight portions, Borneolum Syntheticum 10～20 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 10～20 weight portions, the Radix Astragali 20～30 weight portions, the Rhizoma Atractylodis Macrocephalae 15～25 weight portions, Radix Et Caulis Acanthopanacis Senticosi 10～20 weight portions, Radix Glycyrrhizae 30～40 weight portions.
The said Chinese medicine composition that is used to treat pig eczema, the ratio of weight and number of various components also can further be preferably: the Rhizoma Anemarrhenae 85～90 weight portions, Herba Taraxaci 45～50 weight portions, Rhizoma Saururi (Herba Saururi) 60～65 weight portions, Herba Senecionis Scandentis 50～55 weight portions, Fructus Xanthii 35～40 weight portions, Radix Gentianae 25～30 weight portions, Cortex Pseudolaricis 20～25 weight portions, Bulbus Allii 25～30 weight portions, the Radix Stemonae 25～30 weight portions, Cortex Dictamni 20～25 weight portions, the Fructus Kochiae 15～20 weight portions, Pericarpium Zanthoxyli 25～30 weight portions, Radix Sophorae Flavescentis 20～25 weight portions, Borneolum Syntheticum 15～20 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 15～20 weight portions, the Radix Astragali 25～30 weight portions, the Rhizoma Atractylodis Macrocephalae 20～25 weight portions, Radix Et Caulis Acanthopanacis Senticosi 15～20 weight portions, Radix Glycyrrhizae 35～40 weight portions.
The said Chinese medicine composition that is used to treat pig eczema, the ratio of weight and number of various components also can further be preferably: the Rhizoma Anemarrhenae 85 weight portions, Herba Taraxaci 45 weight portions, Rhizoma Saururi (Herba Saururi) 60 weight portions, Herba Senecionis Scandentis 50 weight portions, Fructus Xanthii 35 weight portions, Radix Gentianae 25 weight portions, Cortex Pseudolaricis 20 weight portions, Bulbus Allii 25 weight portions, the Radix Stemonae 25 weight portions, Cortex Dictamni 20 weight portions, the Fructus Kochiae 15 weight portions, Pericarpium Zanthoxyli 25 weight portions, Radix Sophorae Flavescentis 20 weight portions, Borneolum Syntheticum 15 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 15 weight portions, the Radix Astragali 25 weight portions, the Rhizoma Atractylodis Macrocephalae 20 weight portions, Radix Et Caulis Acanthopanacis Senticosi 15 weight portions, Radix Glycyrrhizae 35 weight portions.
The present invention also provides the above-mentioned method for preparing that is used to treat the Chinese medicine composition of pig eczema, and it comprises:
The first step with each the component proportional mixing in the said Chinese medicine composition, is ground into 100 orders～200 purpose powder; Adding, decocted 30 minutes～1 hour under 90 ℃～100 ℃ temperature with respect to the water of 3～5 times of mixture qualities; Decoction liquor is filtered, and obtains first filtrate and filtering residue;
In second step, the filtering residue that the first step is obtained adds the water with respect to 1～3 times of first step mixture quality, under 90 ℃～100 ℃ temperature, decocts 30 minutes～1 hour, and decoction liquor is filtered, and obtains second filtrate;
The 3rd step merged first filtrate and second filtrate, obtained decoction liquor.
The present invention also provides a kind of feedstuff, comprises in the said feedstuff that feed vector and above-mentioned Chinese medicine composition are as additive.
The percentage by weight of each component does in the said feedstuff, feed vector 50%～80%, the additive 6%～8% of said Chinese medicine composition.
Wherein, said feed vector comprises one or more mixing in Fructus Hordei Vulgaris, Semen Tritici aestivi, the corn.
The present invention also provides the method for preparing of above-mentioned feedstuff, and it comprises:
The first step with each the component proportional mixing in the said Chinese medicine composition, is ground into 100 orders～200 purpose powder; Adding, decocted 30 minutes～1 hour under 90 ℃～100 ℃ temperature with respect to the water of 3～5 times of mixture qualities; Decoction liquor is filtered, and obtains first filtrate and filtering residue;
In second step, the filtering residue that the first step is obtained adds the water with respect to 1～3 times of first step mixture quality, under 90 ℃～100 ℃ temperature, decocts 30 minutes～1 hour, and decoction liquor is filtered, and obtains second filtrate;
The 3rd step merged first filtrate and second filtrate, and concentrating under reduced pressure removes and desolvates; Obtain and get dry extract, it is dry that dried cream is put into spray dryer, guarantees that EAT is at 170 ℃～190 ℃; 60 ℃～80 ℃ of leaving air temps are ground into 200 orders～400 orders subsequently, obtain the Chinese medicine composition powder;
The 4th step; Feed vector is ground into 100 orders～200 purpose powder,, pours in the granulating disc that places heeling condition with the Chinese medicine composition powder mixes that the 3rd step obtained; Open granulating disc and make its rotation; Mixture in granulating disc evenly sprays vaporific high fructose syrup 20% concentration water diluent simultaneously, and the weight of said high fructose syrup water diluent is 1/5～1/10 of said mixture quality, and the rotating speed of granulating disc is 50 rev/mins; Preparation time is 15 minutes, is prepared into diameter and is 1 millimeter spherical particle feedstuff;
In the 5th step, with the spherical particle feedstuff that the 4th step obtained, the stand is put on the mesh-belt drier with the portable rustless steel guipure of multilamellar, and heat drying 10 minutes, the import pathogenic wind-warm of heating degree are 150 degree, and outlet pathogenic wind-warm degree is 80 degree, obtains exsiccant feed granules.
Food or medicine that the present invention also provides the pig feed that is used to treat pig eczema to use, said food or medicine comprise above-mentioned Chinese medicine composition.
The present invention also provides above-mentioned Chinese medicine composition to treat the food of pig eczema or the application in the medicine in preparation.
The pharmacology of said each component is following:
The Rhizoma Anemarrhenae: latin name Anemarrhenae Rhizoma, bitter in the mouth, sweet, cold in nature, go into lung, stomach, kidney channel, the relieving restlessness of purging heat is arranged, the effect of nourshing Yin and drynsessmoistening prescription, clearing away lung-heat to relieve cough cures mainly fever caused by exogenous pathogenic factors, and hyperpyrexia is irritated, lung-heat type cough, interior-heat symptom such as quench one's thirst; Its bitter cold matter profit, the property sedimentation can heat clearing away, can promote the production of body fluid again, kindly controls warm pathogenic factor and goes into edema caused by disorder of QI, the intenseness of heat impairment of body fluid; Also be used to treat diabetes; Phlegm-heat obstructing in the lung and breathing heavily, the xeropulmonary cough, expectorant is few unfavorable; Hyperactivity of fire caused by deficiency of YIN, symptoms such as hyperactivity of deficient fire, the Rhizoma Anemarrhenae has inhibitory action to various bacteria such as dysentery bacterium, Bacillus typhi, escherichia coli, Bacillus proteus, staphylococcus, streptococcus.
Herba Taraxaci: latin name Typhae Pollen, sweet in the mouth, hardship, cold in nature; Go into liver, stomach warp, have the effect of heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, liver heat removing and eyesight improving, inducing diuresis for treating stranguria syndrome, be mainly used in the treatment of sore swollen toxin; Especially remarkable to the acute mastitis effect; Also can be used for the treatment of the symptoms such as conjunctival congestion and swelling pain of flaming up of liver-fire, in addition, also have the effect of promoting urination to remove dampness; Be used to control treatment of conditions such as jaundice due to damp-heat, dysuria, urinary system infection, common reply Staphyloccocus aureus, escherichia coli, bacillus pyocyaneus, shigella flexneri, paratyphoid fever, white beads Niu Jun, cattle type Brucella have certain bacteriostasis; To Trichophyton concentricunm, permitted haze achorion, the little sporeformer of rust, Gypsum Fibrosum appearance budlet spore tinea bacterium etc. bacteriostasis all arranged.
Rhizoma Saururi (Herba Saururi): latin name Saururi Herba, sweet in the mouth, suffering, cold in nature, return lung, urinary bladder channel, have clearing away heat and promoting diuresis; The effect of removing toxic substances and promoting subsidence of swelling cures mainly pyretic stranguria; Stranguria with blood; Edema; Foot gas; Jaundice; Dysentery; Leukorrhagia; Carbuncle sore tumefacting virus; Eczema; Cards such as venom.
Herba Senecionis Scandentis: latin name Senecionis Scandentis Hebra, cold in nature, bitter in the mouth is returned lung, Liver Channel, has heat-clearing and toxic substances removing, an effect of the dampness removing that makes eye bright, and has cards such as carbuncle sore tumefacting virus, cold, fever, conjunctival congestion and swelling pain, dysentery, skin eczema.
Fructus Xanthii: latin name Xanthii Fructus, acrid in the mouth, hardship, warm in nature, return lung meridian, have the function of diffusing wind dehumidifying, understand things pain-stopping, cure mainly nasal sinusitis; Headche due to wind-cold; Rheumatic arthralgia; Rubella; Eczema; Cards such as scabies.Modern pharmacological research confirms that these article have effects such as antimicrobial, antiinflammatory, analgesia, immunosuppressant, antioxidation, and Fructus Xanthii has the mononuclear phagocyte activate the phagocytic capacity of enhancing and active oxygen intermediate product to increase the effect that alleviates delayed hypersensitivity.
Radix Gentianae: latin name Gentianae Radix et Rhizoma, bitter in the mouth, cold in nature, return liver, gallbladder meridian, have the effect of heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire; Cure mainly jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, eczema pruritus, liver-fire conjunctival congestion; Hiccough and deaf, hypochondriac pain bitter taste, persistent erection of the penis, cards such as convulsion with spasms.
Cortex Pseudolaricis: latin name Pseudolaricis Cortex, acrid in the mouth, warm in nature, return lung, spleen channel, have parasite killing, the itching relieving effect cures mainly the scabies pruritus.
Bulbus Allii: latin name Allii Sativi Bulbus; Acrid in the mouth; Warm in nature; Go into spleen, stomach, lung meridian, have that warming middle-JIAO helps digestion, row stagnates gas, warming the spleen and stomach, removing food stagnancy, detoxifcation, parasiticidal effect, cure mainly eating accumulation, coldness and pain in the epigastrium, edema distension, have loose bowels, cards such as dysentery, malaria, pertussis, swollen ulcer drug, white bald tinea skin ulcer, snake bite and insect sting and ancylostome, pinworm.
The Radix Stemonae: latin name Stemonae Radix, sweet in the mouth, hardship, slightly warm in nature is returned lung meridian, has nourishing the lung to keep the adverse QI downward cough-relieving, and parasiticidal effect cures mainly new chronic cough and coughs, pulmonary tuberculosis cough, pertussis; Be used for head louse outward, body louse, enterobiasis, cards such as pudendum Pruritus.
Cortex Dictamni: latin name Dictamni Cortex, bitter in the mouth, salty, cold in nature, return spleen channel; Lung meridian; Small intestine meridian; The stomach warp; Urinary bladder channel has heat clearing and damp drying; Dispelling wind for relieving itching; The antidotal effect cures mainly the rubella due to the wind heat noxious dampness; Eczema; Scabies; Jaundice; Cards such as damp and hot arthralgia pain.
The Fructus Kochiae: latin name Kochiae Fructus, cold in nature, acrid in the mouth, hardship have clearing away heat-damp and promoting diuresis, and the effect of dispelling wind for relieving itching cures mainly cards such as difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus.
Pericarpium Zanthoxyli: latin name Zanthoxyli Pericarpium, acrid in the mouth, warm in nature, return spleen, stomach, kidney channel.Have the function of warming middle-JIAO to relieve pain, killing parasites for relieving itching, cure mainly coldness and pain in the epigastrium, vomiting is had loose bowels, abdominal pain due to worm stagnation, ascariasis; Cards such as external treatment eczema pruritus.
Radix Sophorae Flavescentis: latin name Sophorae Flavescentis Radix, bitter in the mouth; Cold in nature, go into liver; Kidney; Large intestine; Small intestinal; Bladder; Heart channel has heat clearing and damp drying, parasite killing, and the diuretic effect cures mainly hematodiarrhoea, has blood in stool jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, cards such as scabies leprosy.
Borneolum Syntheticum: latin name Borneolum Syntheticum, acrid in the mouth, hardship, cool in nature, go into the heart, lung meridian, have logical all keys; Diffusing stagnated fire goes nebula to make eye bright, and the effect of reducing swelling and alleviating pain cures mainly the apoplexy locked mouth, the calentura coma; Infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media; Carbuncle, hemorrhoid, order is the nebula film also, cards such as enterobiasis.
Pseudobulbus Bletillae (Rhizoma Bletillae): latin name Bletillae Rhizoma, bitter in the mouth, sweet, puckery, cold nature is returned lung, liver, stomach warp, has tonifying the lung, hemostasis; Detumescence, granulation promoting is held back the effect of skin ulcer, cures mainly lung and hinders hemoptysis, epistaxis; Incised wound is hemorrhage, swollen ulcer drug, and ulcer pain, the soup fire is burnt, cards such as rhagadia manus et pedis.
The Radix Astragali: latin name Astragali Radix, sweet in the mouth, warm in nature; Go into spleen, lung meridian, have tonification spleen soil, elevate a turnable ladder yang-energy, strengthening superficial resistance to stop perspiration; The effect of holder skin ulcer granulation promoting cures mainly the weak anorexia and loose stool due to the deficiency of both the splenic and pulmonary QI, shortness of breath and palpitation; The visceroptosis of sinking of QI of middle-JIAO, the metrorrhagia of QI failing to control blood is had blood in stool, the chronic diarrhea proctoptosis; The spontaneous sweating of exterior deficiency, cards such as insufficiency of vital energy and blood.
The Rhizoma Atractylodis Macrocephalae: latin name Attractylodis Macrocephalae Rhizoma, sweet in the mouth, hardship, warm in nature, go into spleen, stomach warp; The spleen reinforcing promoting the circulation of QI is arranged, dampness diuretic, strengthening superficial resistance to stop perspiration; The effect that activating the spleen is moisturized cures mainly the feeling of fullness diarrhoea due to dysfunction of the spleen in transportation, the QI failing to transform into body fluid, the phlegm retention edema; The vexed lazy speech of deficiency of QI in middle-JIAO, metrorrhagia and metrostaxis, proctoptosis with chronic dysentery; Cards such as solid in the playing of deficiency of the spleen causing weakness of QI, sweating due to debility spontaneous perspiration, the Rhizoma Atractylodis Macrocephalae can promote gastric secretion, strengthens the Absorption of small intestinal, and gastrointestinal function is had regulating action.
Radix Et Caulis Acanthopanacis Senticosi: latin name Acanthopanacis Senticosi Radix et Rhizomaseu Caulis; Acrid in the mouth, hardship, little sweet, warm in nature are gone into spleen, kidney, heart channel; Has replenishing QI to invigorate the spleen; Tonifying the kidney for tranquilization, the effect of expelling wind and removing dampness, be used for anemofrigid-damp arthralgia, lumbocrural pain, muscles and bones flaccidity soft, be slow in action, card such as the body weakness with emaciation is weak, traumatic injury, fracture, edema, beriberi, uncontrolled urination are itched.
Radix Glycyrrhizae: latin name Glycyrrhizae Radix et Rhizoma, sweet in the mouth, property is flat, goes into 12 warps, and heat-clearing and toxic substances removing is arranged, and is in harmonious proportion the property of medicine, the effect of expelling phlegm for arresting cough, and can spleen invigorating with in, relieving spasm to stop pain is mainly used in the abdominal distension and anorexia of weakness of the spleen and stomach, and is weak; Can alleviate contracture property pain in the abdomen, relax the strong and toxicity of some drugs, alleviating medicine stimulates to the toxic and side effects of body or to gastrointestinal, can play the QI invigorating neutralization through adding Radix Glycyrrhizae, is in harmonious proportion the effect of each component.
Below adopt embodiment to specify embodiment of the present invention, how the application technology means solve technical problem to the present invention whereby, and the implementation procedure of reaching technique effect can make much of and implement according to this.
Embodiment 1 Chinese medicine composition decoction liquor 1
Rhizoma Anemarrhenae 85g, Herba Taraxaci 45g, Rhizoma Saururi (Herba Saururi) 60g, Herba Senecionis Scandentis 50g, Fructus Xanthii 35g, Radix Gentianae 25g, Cortex Pseudolaricis 20g, Bulbus Allii 25g, Radix Stemonae 25g, Cortex Dictamni 20g, Fructus Kochiae 15g, Pericarpium Zanthoxyli 25g, Radix Sophorae Flavescentis 20g, Borneolum Syntheticum 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Radix Astragali 25g, Rhizoma Atractylodis Macrocephalae 20g, Radix Et Caulis Acanthopanacis Senticosi 15g, Radix Glycyrrhizae 35g are mixed, be ground into 100 purpose powder, add the water of 2300g; Under 100 ℃ temperature, decocted 40 minutes, decoction liquor is filtered; Obtain first filtrate and filtering residue; Water with the filtering residue adding 1500g that obtains under 100 ℃ temperature, decocted 40 minutes; Decoction liquor is filtered; Obtain second filtrate, first filtrate and second filtrate are merged, obtain decoction liquor 1.
Acute toxicity test
1. experimental animal
The healthy KM mice of SPF level, 30, male and female half and half, body weight 20-25g.
2. detectable
Serum AST, ALT detection kit are helped Industrial Co., Ltd. available from the Shanghai coloured silk.
3. checkout equipment
Micro-200 semiautomatic biochemistry detector, analytical balance, dissecting instrument, syringe, test tube etc.
4. test method
After 3 days adaptabilities are raised, be divided into 4 groups (male and female half and half) at random, every group each 10; Matched group, 3 various dose experimental grouies (be respectively 76mg (crude drug)/only, 219.9mg (crude drug)/only, 357.6mg (crude drug)/only); Each experimental group is irritated the decoction liquor 1 of clothes embodiment 1 preparation, and mice free choice feeding, drinking-water are in the feeding process; Change water every day, the next day change bedding and padding.The whole test phase is 7 days.
5. testing index and method
(1) clinicing symptom observation: every day the viewing test Mus the mental status, diet situation, record morbidity every day death condition.
(2) pathological observation: cut open inspection for dead Mus and observe the internal organs variation.
(3) growth indexes is observed: the test Mus is carried out routine weighing; Off-test, slaughter that Mus weighs in, the heavy organ index of internal organs measures: cut open the inspection kunming mice, dirty, the spleen of coring, liver, kidney, testis, ovary are weighed, according to the computes organ index: organ index=internal organs weight/body weight * 100.
(4) liver function changes observation: after the off-test, slaughter Mus, take blood separation serum, measure AST, ALT.
6. date processing: above The data SPSS11.0 carries out analytic statistics.
Clinicing symptom observation
Matched group and test group Mus, the mental status and diet are desired, respond is not seen significantly unusual to external world.Each organizes Mus morbidity and death condition such as following table 1.
Table 1
Pathological observation: matched group and test group, cut open after Mus is slaughtered to examine to observe and do not see the tangible pathological change of observation internal organs.
Growth indexes is observed: off-test, slaughter that Mus weighs in, the internal organs weight analysis is seen table 2.
Table 2
Liver function changes to be observed
After the off-test, slaughter Mus, take blood separation serum, mensuration AST, ALT see table 3.The result shows and respectively organizes data and normal healthy controls group to compare difference not remarkable, all is in normal range.
Table 3
Long term toxicity test
Get 10 of adult ill pigs; Body weight is at 150～200kg; Long term toxicity test is carried out in the long-term administration of half and half, 12 week of male and female; The result shows that the equal no abnormality seen of indexs such as the general situation of all pigs, growth promoter, routine blood test, liver, renal function changes, and histopathology and gross necropsy are not also seen pathological change.
Embodiment 2 Chinese medicine composition decoction liquor 2
Rhizoma Anemarrhenae 90g, Herba Taraxaci 42g, Rhizoma Saururi (Herba Saururi) 63g, Herba Senecionis Scandentis 52g, Fructus Xanthii 38g, Radix Gentianae 22g, Cortex Pseudolaricis 17g, Bulbus Allii 21g, Radix Stemonae 28g, Cortex Dictamni 25g, Fructus Kochiae 12g, Pericarpium Zanthoxyli 20g, Radix Sophorae Flavescentis 25g, Borneolum Syntheticum 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 18g, Radix Astragali 29g, Rhizoma Atractylodis Macrocephalae 23g, Radix Et Caulis Acanthopanacis Senticosi 11g, Radix Glycyrrhizae 38g are mixed, be ground into 100 purpose powder, add the water of 2300g; Under 100 ℃ temperature, decocted 40 minutes, decoction liquor is filtered; Obtain first filtrate and filtering residue; Water with the filtering residue adding 1500g that obtains under 100 ℃ temperature, decocted 40 minutes; Decoction liquor is filtered; Obtain second filtrate, first filtrate and second filtrate are merged, obtain decoction liquor 2.
Embodiment 3 Chinese medicine composition decoction liquor 3
Rhizoma Anemarrhenae 85g, Herba Taraxaci 48g, Rhizoma Saururi (Herba Saururi) 66g, Herba Senecionis Scandentis 48g, Fructus Xanthii 36g, Radix Gentianae 26g, Cortex Pseudolaricis 22g, Bulbus Allii 28g, Radix Stemonae 24g, Cortex Dictamni 25g, Fructus Kochiae 10g, Pericarpium Zanthoxyli 28g, Radix Sophorae Flavescentis 22g, Borneolum Syntheticum 12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 14g, Radix Astragali 25g, Rhizoma Atractylodis Macrocephalae 17g, Radix Et Caulis Acanthopanacis Senticosi 16g, Radix Glycyrrhizae 40g are mixed, be ground into 100 purpose powder, add the water of 2300g; Under 100 ℃ temperature, decocted 40 minutes, decoction liquor is filtered; Obtain first filtrate and filtering residue; Water with the filtering residue adding 1500g that obtains under 100 ℃ temperature, decocted 40 minutes; Decoction liquor is filtered; Obtain second filtrate, first filtrate and second filtrate are merged, obtain decoction liquor 3.
Embodiment 4 feedstuffs 1
Rhizoma Anemarrhenae 85g, Herba Taraxaci 45g, Rhizoma Saururi (Herba Saururi) 60g, Herba Senecionis Scandentis 50g, Fructus Xanthii 35g, Radix Gentianae 25g, Cortex Pseudolaricis 20g, Bulbus Allii 25g, Radix Stemonae 25g, Cortex Dictamni 20g, Fructus Kochiae 15g, Pericarpium Zanthoxyli 25g, Radix Sophorae Flavescentis 20g, Borneolum Syntheticum 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Radix Astragali 25g, Rhizoma Atractylodis Macrocephalae 20g, Radix Et Caulis Acanthopanacis Senticosi 15g, Radix Glycyrrhizae 35g are mixed, be ground into 100 purpose powder, add the water of 2300g, under 100 ℃ temperature; Decocted 40 minutes, decoction liquor is filtered, and obtains first filtrate and filtering residue; Water with the filtering residue adding 1500g that obtains under 100 ℃ temperature, decocted 40 minutes; Decoction liquor is filtered, and obtains second filtrate, and first filtrate and second filtrate are merged; Concentrating under reduced pressure removes and desolvates, and obtains to get dry extract, and it is dry that dried cream is put into spray dryer; Guarantee EAT at 180 ℃, 70 ℃ of leaving air temps are ground into 200 orders subsequently; Obtain the Chinese medicine composition powder, the 5kg wheat flour is broken into 100 purpose powder, with the Chinese medicine composition powder mixes of front acquisition; Pour in the granulating disc that places heeling condition, open granulating disc and make its rotation, the mixture in granulating disc evenly sprays vaporific high fructose syrup 20% concentration water diluent 700g simultaneously; The rotating speed of granulating disc is 50 rev/mins, and preparation time is 15 minutes, is prepared into diameter and is 1 millimeter spherical particle feedstuff; With the spherical particle feedstuff that obtains, the stand is put on the mesh-belt drier with the portable rustless steel guipure of multilamellar, heat drying 10 minutes; The import pathogenic wind-warm of heating degree is 150 degree, and outlet pathogenic wind-warm degree is 80 degree, obtains exsiccant feed granules 1.
Embodiment 5 feedstuffs 2
Rhizoma Anemarrhenae 90g, Herba Taraxaci 42g, Rhizoma Saururi (Herba Saururi) 63g, Herba Senecionis Scandentis 52g, Fructus Xanthii 38g, Radix Gentianae 22g, Cortex Pseudolaricis 17g, Bulbus Allii 21g, Radix Stemonae 28g, Cortex Dictamni 25g, Fructus Kochiae 12g, Pericarpium Zanthoxyli 20g, Radix Sophorae Flavescentis 25g, Borneolum Syntheticum 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 18g, Radix Astragali 29g, Rhizoma Atractylodis Macrocephalae 23g, Radix Et Caulis Acanthopanacis Senticosi 11g, Radix Glycyrrhizae 38g are mixed, be ground into 100 purpose powder, add the water of 2300g, under 100 ℃ temperature; Decocted 40 minutes, decoction liquor is filtered, and obtains first filtrate and filtering residue; Water with the filtering residue adding 1500g that obtains under 100 ℃ temperature, decocted 40 minutes; Decoction liquor is filtered, and obtains second filtrate, and first filtrate and second filtrate are merged; Concentrating under reduced pressure removes and desolvates, and obtains to get dry extract, and it is dry that dried cream is put into spray dryer; Guarantee EAT at 180 ℃, 70 ℃ of leaving air temps are ground into 200 orders subsequently; Obtain the Chinese medicine composition powder, the 5kg wheat flour is broken into 100 purpose powder, with the Chinese medicine composition powder mixes of front acquisition; Pour in the granulating disc that places heeling condition, open granulating disc and make its rotation, the mixture in granulating disc evenly sprays vaporific high fructose syrup 20% concentration water diluent 700g simultaneously; The rotating speed of granulating disc is 50 rev/mins, and preparation time is 15 minutes, is prepared into diameter and is 1 millimeter spherical particle feedstuff; With the spherical particle feedstuff that obtains, the stand is put on the mesh-belt drier with the portable rustless steel guipure of multilamellar, heat drying 10 minutes; The import pathogenic wind-warm of heating degree is 150 degree, and outlet pathogenic wind-warm degree is 80 degree, obtains exsiccant feed granules 2.
Embodiment 6 clinical experiments
Laboratory animal
Select to breathe out 168 of white piglets, ill piglet is 42～60 ages in days, skin generation pimple, and the piglet of pruritus is a skin eczema through clinical definite.
Test method
With every nest is basic random packet, is divided into 2 treatment groups.The treatment group adopts the Chinese medicine composition decoction liquor 1 of the embodiment of the invention 1 preparation, and is for oral administration, the morning, noon and afternoon each once, each 500ml; Matched group adopts intramuscular injection penicillin, every 800,000 u.
Criterion of therapeutical effect
It is 5 days that natural law is controlled in examination, and skin rashes disappears within 5 d, and pruritus is not obvious for curing; It is not obvious to disappear above 5 d person's skin rashes, and pruritus is invalid.
Therapeutic outcome
The result sees table 4, sees from therapeutic effect, adopts Chinese medicine composition of the present invention the highest to the marmite disease cure rate, and cure rate is 97.6%, and is higher than matched group intramuscular injection penicillin.
Table 4
Model case 1
Raise main Liu, totally 27 of a brood of piglets are arranged, 30 ages in days, every 10kg suffers from the pig down in spirits; Slightly disorderly, there is punctation lower abdomen and extremity inboard, have three piglets to form flat blister, and the consistence transudate is arranged for loss of appetite, fur; 40.5 ℃ of body temperature, the Chinese medicine composition of irritating 1 preparation of the clothes embodiment of the invention decocts agent 1, and every day 3 times, every day, 500ml took 4 days; 24 pigletss are being taken decrustation two days later, recovery from illness, and 3 pigletss, red shadow disappeared in the 2nd day, and transudate reduces; Body temperature is normal, and redness all disappeared in the 3rd day, had the crust and the perk of one deck black, the 4th day decrustation, recovery from illness.
Model case 2
3 years old sow of Wu family is invited and examines.Disease is seen: all over the big pimple of the grain of rice to Semen Glycines, pruritus is uneasy, on the circle wall, rubs frequently, and is wounded and bleeding, through all not imitating with treatments such as antibiotic, PIYANPING, sulphur ointment, avilamycin.The Chinese medicine composition of taking the embodiment of the invention 2 preparation decocts 2 morning, noon and afternoon of agent each 1 time, each 500ml, and logotype 5 days does not promptly have pruritus, continues medication 2 days for consolidating curative effect, visits after January and does not have recurrence.
Model case 3
One 50 age in days piglets of Liu family finds that the right side groin three circles takes place is concentrically ringed pimple, about about 15 cm of skin lesion area * 18 cm.Inspection: be everlasting wall, crib, pile place of coarse, the edema of pars affecta skin, sick pig wiped and itched, and after the pimple galling, flows out yellow thick liquid, forms furfur appearance brown crust, and to xiphoid-process, the back was to scrotum portion before affected part had expanded to.Treatment: take the feed granules of the embodiment of the invention 4 preparations, normal feeding, logotype 7 days, the brown decrustation, pimple portion edema goes down, and visits and does not have recurrence.
Model case 4
Chen buys 100 piglets from the other places, all weigh 20 kilograms, because long-distance transport adds that colony house is too crowded; And cleaning and sterilizing is not tight; The 3rd day part piglet skin that causes marching into the arena begins Pruritus, and then congested, punctation occurs; Each other merge and fester, the short time causes that rapidly eczema in various degree only appears in most of pig.At first use potassium permanganate solution to clean affected part; The Chinese medicine composition of taking the embodiment of the invention 3 preparations again decocts agent 3; Every pig every day 3 times, each 500ml, most of red shadow of pig of suffering from disappeared in the 3rd day; The visible 1 layer of furfur appearance black crust projection in surface, the trouble pig of serious symptom is used antibiotic to prevent secondary infection.The whole rehabilitations of sick pig in the 5th day.
This intellectual property of primary enforcement that all are above-mentioned is not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above only is preferred embodiment of the present invention, is not to be the restriction of the present invention being made other form, and any professional and technical personnel of being familiar with possibly utilize the technology contents of above-mentioned announcement to change or be modified as the equivalent embodiment of equivalent variations.But everyly do not break away from technical scheme content of the present invention, to any simple modification, equivalent variations and remodeling that above embodiment did, still belong to the protection domain of technical scheme of the present invention according to technical spirit of the present invention.
Claims (10)
1. Chinese medicine composition that is used to treat pig eczema; It is characterized in that, comprising: the Rhizoma Anemarrhenae, Herba Taraxaci, Rhizoma Saururi (Herba Saururi), Herba Senecionis Scandentis, Fructus Xanthii, Radix Gentianae, Cortex Pseudolaricis, Bulbus Allii, the Radix Stemonae, Cortex Dictamni, the Fructus Kochiae, Pericarpium Zanthoxyli, Radix Sophorae Flavescentis, Borneolum Syntheticum, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Et Caulis Acanthopanacis Senticosi and Radix Glycyrrhizae.
2. Chinese medicine composition as claimed in claim 1 is characterized in that:
The ratio of weight and number of said various components is the Rhizoma Anemarrhenae 80～90 weight portions, Herba Taraxaci 40～50 weight portions, Rhizoma Saururi (Herba Saururi) 55～65 weight portions, Herba Senecionis Scandentis 45～55 weight portions, Fructus Xanthii 30～40 weight portions, Radix Gentianae 20～30 weight portions, Cortex Pseudolaricis 15～25 weight portions, Bulbus Allii 20～30 weight portions, the Radix Stemonae 20～30 weight portions, Cortex Dictamni 15～25 weight portions, the Fructus Kochiae 10～20 weight portions, Pericarpium Zanthoxyli 20～30 weight portions, Radix Sophorae Flavescentis 15～25 weight portions, Borneolum Syntheticum 10～20 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 10～20 weight portions, the Radix Astragali 20～30 weight portions, the Rhizoma Atractylodis Macrocephalae 15～25 weight portions, Radix Et Caulis Acanthopanacis Senticosi 10～20 weight portions, Radix Glycyrrhizae 30～40 weight portions.
3. according to claim 1 or claim 2 Chinese medicine composition is characterized in that:
The ratio of weight and number of various components is the Rhizoma Anemarrhenae 85～90 weight portions, Herba Taraxaci 45～50 weight portions, Rhizoma Saururi (Herba Saururi) 60～65 weight portions, Herba Senecionis Scandentis 50～55 weight portions, Fructus Xanthii 35～40 weight portions, Radix Gentianae 25～30 weight portions, Cortex Pseudolaricis 20～25 weight portions, Bulbus Allii 25～30 weight portions, the Radix Stemonae 25～30 weight portions, Cortex Dictamni 20～25 weight portions, the Fructus Kochiae 15～20 weight portions, Pericarpium Zanthoxyli 25～30 weight portions, Radix Sophorae Flavescentis 20～25 weight portions, Borneolum Syntheticum 15～20 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 15～20 weight portions, the Radix Astragali 25～30 weight portions, the Rhizoma Atractylodis Macrocephalae 20～25 weight portions, Radix Et Caulis Acanthopanacis Senticosi 15～20 weight portions, Radix Glycyrrhizae 35～40 weight portions.
4. like the described Chinese medicine composition of claim 1 to 3, it is characterized in that:
The ratio of weight and number of various components is the Rhizoma Anemarrhenae 85 weight portions, Herba Taraxaci 45 weight portions, Rhizoma Saururi (Herba Saururi) 60 weight portions, Herba Senecionis Scandentis 50 weight portions, Fructus Xanthii 35 weight portions, Radix Gentianae 25 weight portions, Cortex Pseudolaricis 20 weight portions, Bulbus Allii 25 weight portions, the Radix Stemonae 25 weight portions, Cortex Dictamni 20 weight portions, the Fructus Kochiae 15 weight portions, Pericarpium Zanthoxyli 25 weight portions, Radix Sophorae Flavescentis 20 weight portions, Borneolum Syntheticum 15 weight portions, Pseudobulbus Bletillae (Rhizoma Bletillae) 15 weight portions, the Radix Astragali 25 weight portions, the Rhizoma Atractylodis Macrocephalae 20 weight portions, Radix Et Caulis Acanthopanacis Senticosi 15 weight portions, Radix Glycyrrhizae 35 weight portions.
5. like the method for preparing of the described Chinese medicine composition of claim 1 to 4, it is characterized in that, comprising:
The first step with each the component proportional mixing in the said Chinese medicine composition, is ground into 100 orders～200 purpose powder; Adding, decocted 30 minutes～1 hour under 90 ℃～100 ℃ temperature with respect to the water of 3～5 times of mixture qualities; Decoction liquor is filtered, and obtains first filtrate and filtering residue;
In second step, the filtering residue that the first step is obtained adds the water with respect to 1～3 times of first step mixture quality, under 90 ℃～100 ℃ temperature, decocts 30 minutes～1 hour, and decoction liquor is filtered, and obtains second filtrate;
The 3rd step merged first filtrate and second filtrate, obtained decoction liquor.
6. a feedstuff that is used to treat pig eczema is characterized in that: comprise in the said feedstuff that the described Chinese medicine composition of feed vector and claim 1 to 4 is as additive.
7. feedstuff as claimed in claim 6 is characterized in that: the percentage by weight of each component does in the said feedstuff, said feed vector 50%～80%, the additive 6%～8% of said Chinese medicine composition.
8. like the method for preparing of claim 6 or 7 described feedstuffs, it is characterized in that, comprising:
The first step; With each the component proportional mixing in the said Chinese medicine composition of claim 1 to 4, be ground into 100 orders～200 purpose powder, add water with respect to 3～5 times of mixture qualities; Under 90 ℃～100 ℃ temperature; Decocted 30 minutes～1 hour, decoction liquor is filtered, and obtains first filtrate and filtering residue;
In second step, the filtering residue that the first step is obtained adds the water with respect to 1～3 times of first step mixture quality, under 90 ℃～100 ℃ temperature, decocts 30 minutes～1 hour, and decoction liquor is filtered, and obtains second filtrate;
The 3rd step merged first filtrate and second filtrate, and concentrating under reduced pressure removes and desolvates; Obtain and get dry extract, it is dry that dried cream is put into spray dryer, guarantees that EAT is at 170 ℃～190 ℃; 60 ℃～80 ℃ of leaving air temps are ground into 200 orders～400 orders subsequently, obtain the Chinese medicine composition powder;
The 4th step; Feed vector is ground into 100 orders～200 purpose powder,, pours in the granulating disc that places heeling condition with the Chinese medicine composition powder mixes that the 3rd step obtained; Open granulating disc and make its rotation; Mixture in granulating disc evenly sprays vaporific high fructose syrup 20% concentration water diluent simultaneously, and the weight of said high fructose syrup water diluent is 1/5～1/10 of said mixture quality, and the rotating speed of granulating disc is 50 rev/mins; Preparation time is 15 minutes, is prepared into diameter and is 1 millimeter spherical particle feedstuff;
In the 5th step, with the spherical particle feedstuff that the 4th step obtained, the stand is put on the mesh-belt drier with the portable rustless steel guipure of multilamellar, and heat drying 10 minutes, the import pathogenic wind-warm of heating degree are 150 degree, and outlet pathogenic wind-warm degree is 80 degree, obtains exsiccant feed granules.
9. a food or medicine that the pig feed that is used to treat pig eczema is used, it is characterized in that: said food or medicine comprise the described Chinese medicine composition of claim 1 to 4.
10. the described Chinese medicine composition of claim 1 to 4 is in the food of preparation treatment pig eczema or the application in the medicine.
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| CN102987092A (en) * | 2012-10-08 | 2013-03-27 | 安徽长风农牧科技有限公司 | Feed additive for improving disease resistance of escherichia coli |
| CN105497853A (en) * | 2016-01-06 | 2016-04-20 | 崔仲恩 | Medicine compound for preventing and treating Pietrain skin diseases and preparation method thereof |
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| CN102688430B (en) | 2013-11-20 |
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