CN1091027A - Blood-pressure reducing plaster sticking on acupoint and preparation method thereof - Google Patents
Blood-pressure reducing plaster sticking on acupoint and preparation method thereof Download PDFInfo
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- CN1091027A CN1091027A CN 93111353 CN93111353A CN1091027A CN 1091027 A CN1091027 A CN 1091027A CN 93111353 CN93111353 CN 93111353 CN 93111353 A CN93111353 A CN 93111353A CN 1091027 A CN1091027 A CN 1091027A
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Abstract
A kind of blood-pressure reducing plaster sticking on acupoint and preparation method thereof, its medicament composing prescription and proportioning (%) are: Fructus Evodiae 20-45, Herba Apocyni veneti 20-30, Ramulus Uncariae Cum Uncis 10-25, Radix Stephaniae Tetrandrae 6-16, Rhizoma Acori Graminei 6-12, Spica Prunellae 5-15, Herba Dendrobii 3-7.Its preparation method be raw material preparation, Fructus Evodiae, Herba Apocyni veneti, Radix Stephaniae Tetrandrae, Ramulus Uncariae Cum Uncis, Spica Prunellae, Herba Dendrobii are carried out the ethanol refluxing process extract drugs, Rhizoma Acori Graminei is carried out the decocting method extract drugs, becomes cream and coating.Blood-pressure reducing plaster sticking on acupoint reasonable recipe of the present invention, meet Chinese medical theory, easy to use, long-acting reliable, except that curing mainly hypertension, the conjunctival congestion of the aphtha of the mouth and tongue due to the flaming up of heart-fire, flaming up of liver-fire, bitter taste, dizzy distending pain, muscle arthralgia etc. also there are obvious therapeutic action, its preparation method technology simple possible.
Description
The invention belongs to medical technical scope, relate to a kind of hypertensive dosage form Chinese patent medicine that sticks that cures mainly.
Hypertension is a kind of commonly encountered diseases, frequently-occurring disease, and the prevalence in the adult is about 3-10%.At present, treat this disease, doctor trained in Western medicine adopts tranquilizer and antihypertensive drugs more.Wherein, depressor mainly contains: the diuretic antihypertensive medicine, vasodilator, adrenergic receptor blocker, central depressor, sympathetic inhibitor etc., though the kind of medicine is many, but the treatment of adopting these depressor is the normal phase, or even it is lifelong, and this class medicine is taken for a long time, be prone to some comparatively significant side effects mostly, as weak, headache, dizzy, cardiopalmus, feel sick, abdominal distention, constipation, decreased heart rate etc., sometimes drug withdrawal suddenly, even also may cause hypertensive crisis, blood pressure lowering is too quickly still the heart can to take place, brain, untoward reaction such as kidney complication.Tcm syndrome differentiation and treatment, though can still not have long-acting reliable Chinese patent medicine at present with some untoward reaction of avoiding above-mentioned western medical treatment to cause, the much more general decoctions that adopt decoct, take comparatively trouble, particularly being not easy to goes on business carries and takes.
Task of the present invention provides and a kind ofly has no side effect and do not produce untoward reaction, easy to use, blood-pressure reducing plaster sticking on acupoint that therapeutic effect is good and preparation method thereof, to overcome the above-mentioned shortcoming of treatment hypertension disease medicament in the prior art.
Fructus Evodiae pulverizing vinegar is mixed and sticked two sufficient hearts treatment hypertension, continues to use so far among the people, and is also on the books in some " proved recipe " and " book on Chinese herbal medicine " works.Modern medicine chemical medicine reason studies show that the Main Ingredients and Appearance of Fructus Evodiae is rutaecarpin, evodene, Fructus Evodiae lactone etc., has the peripheral blood vessel of making expansion and plays blood pressure lowering; Herba Apocyni veneti has the cardiac stimulant effect of blood pressure lowering; Ramulus Uncariae Cum Uncis contains multiple alkaloid, suppressing the hyperactive liver, heat clearing away are arranged, relieves dizziness, high fever, infantile convulsions, epilepsy, etc., spasmolysis; Radix Stephaniae Tetrandrae also contains multiple alkaloid, and dispel the wind, diuresis, promoting the circulation of QI to relieve pain, alleviate hypertension dizziness, numb limbs and tense tendons effect; Rhizoma Acori Graminei have have one's ideas straightened out, the effect of expectorant, refreshment brain-strengthening, removing dampness appetizing; Spica Prunellae has the effect of taking a tonic or nourishing food to build up one's health faint cloudy blood vessels and the clear sharp head, mediation stagnation of QI; But Herba Dendrobii YIN nourishing and the production of body fluid promoting; Simultaneously, Yongquan acupoint belongs to kidney meridian go out and is " well ", is apt to have one's ideas straightened out, expels the heat-evil and allay excitement, can pass through its treatment dizziness, headache, hypertension; Quchi acupoint belongs to meridian of Hand-YANG MING go into and is " closing ", is used for wind and heat dispersing, harmonizing yingfen and weifen, treats hypertension for being good at.Stick antihypertensive drugs on the acupuncture point of the type, easily Transdermal absorption had both been brought into play drug effect, brought into play the therapeutical effect at acupuncture point again, and curative effect is increased.Task of the present invention just is based on above Chinese medical theory, realizes with following technical scheme:
Blood-pressure reducing plaster sticking on acupoint of the present invention comprises substrate and carrier, and its medicament composing prescription proportioning is:
Fructus Evodiae 20-45 Herba Apocyni veneti 20-30 Ramulus Uncariae Cum Uncis 10-25
Radix Stephaniae Tetrandrae 6-16 Rhizoma Acori Graminei 6-12 Spica Prunellae 5-15
Herba Dendrobii 3-7
The best is:
Fructus Evodiae 30-35 Herba Apocyni veneti 20-25 Ramulus Uncariae Cum Uncis 15-20
Radix Stephaniae Tetrandrae 8-12 Rhizoma Acori Graminei 6-10 Spica Prunellae 6-10
Herba Dendrobii 5-6
Walk to scurry effect and percutaneous absorbability for the fragrance that strengthens medicine, can also help in the prescription of blood-pressure reducing plaster sticking on acupoint of the present invention and join a spot of Borneolum Syntheticum, behind the Borneolum Syntheticum levigation, when becoming the cream operation, add together.
The preparation method of blood-pressure reducing plaster sticking on acupoint of the present invention is:
(1) raw material is prepared and extract drugs:
(1) take by weighing Fructus Evodiae by proportioning, roguing is pulverized, and adds vinegar moistening and moistening to saturating, with the alcohol reflux of concentration cardinal principle 60%, filter and remove residue is 9-11 with medicinal liquid with strong aqua ammonia acid adjustment basicity to pH value, 10 the most suitable to be roughly, static after, sucking filtration gets precipitate.
(2) take by weighing Herba Apocyni veneti by proportioning,, behind the recovery ethanol, the medicinal liquid water-bath is concentrated into the thick paste shape with the alcohol reflux of concentration cardinal principle 70%, filter and remove residue;
(3) take by weighing Radix Stephaniae Tetrandrae, Ramulus Uncariae Cum Uncis pulverizing by proportioning, with the alcohol reflux of concentration cardinal principle 95%, put cold filter and remove residue separately or together, behind the recovery ethanol, the medicinal liquid water-bath is concentrated into the thick paste shape;
(4) take by weighing Spica Prunellae, Herba Dendrobii by proportioning, with the alcohol reflux of concentration cardinal principle 30%, filter and remove residue behind the recovery ethanol, is concentrated into the thick paste shape with the medicinal liquid water-bath separately or together,
(5) get Rhizoma Acori Graminei by proportioning, decocting extracts its volatile oil earlier, refilters and removes slag, and the medicinal liquid water-bath is concentrated into the thick paste shape.
(2) become cream:
(1) prepares substrate by rubber plaster substrate preparation method;
(2) each medicine that flow process operation () is extracted (comprising the volatile oil that extracts from Rhizoma Acori Graminei) adds in the above-mentioned substrate for preparing, if assistant also adds together with Borneolum Syntheticum in the prescription, stirs;
(3) coating: undertaken by the conventional coating process of rubber plaster.Be the blood-pressure reducing plaster sticking on acupoint finished product of the present invention that the inventive method makes after the coating.
During use, the warm water foot bath, wipe away do after, stick on sufficient heart Yongquan acupoint, with 3-4 days at interval two foots stick by turns and are advisable, if when the state of an illness is heavier, also can stick on the upper limb Quchi acupoint, or about stick simultaneously.
Blood-pressure reducing plaster sticking on acupoint of the present invention is a foundation with the Chinese medical theory, reasonable recipe, the function of tool suppressing the hyperactive liver to relieve the wind syndrome, nourishing YIN for attracting YANG, the spasmolytic of eliminating the phlegm, inducing resuscitation.Drug effect is long, effective, easy to use, except that curing mainly hypertension, conjunctival congestion, bitter taste, dizzy distending pain, muscle arthralgia etc. due to aphtha of the mouth and tongue, the flaming up of liver-fire due to the flaming up of heart-fire are also had significantly auxiliary treatment effect, are a kind of novel forms of Chinese traditional treatment hypertension; Its preparation method, technology is simple, and is rationally feasible.
Claims (5)
1, a kind of blood-pressure reducing plaster sticking on acupoint comprises substrate and carrier, it is characterized in that its medicament composing prescription and proportioning (%) are:
Fructus Evodiae 20-45 Herba Apocyni veneti 20-30 Ramulus Uncariae Cum Uncis 10-25
Radix Stephaniae Tetrandrae 6-16 Rhizoma Acori Graminei 6-12 Spica Prunellae 5-15
Herba Dendrobii 3-7
2, blood-pressure reducing plaster according to claim 1 is characterized in that said proportioning (%) is: Fructus Evodiae 30-35 Herba Apocyni veneti 20-25 Ramulus Uncariae Cum Uncis 15-20
Radix Stephaniae Tetrandrae 8-12 Rhizoma Acori Graminei 6-10 Spica Prunellae 6-10
Herba Dendrobii 5-6
3, blood-pressure reducing plaster according to claim 1 and 2 is characterized in that said prescription, wherein also has a small amount of Borneolum Syntheticum.
4, a kind of preparation method according to the described blood-pressure reducing plaster sticking on acupoint of claim 1 is characterized in that the technological process for preparing is:
(1) raw material is prepared and extract drugs:
(1) get Fructus Evodiae roguing, pulverizing by proportioning, add vinegar moistening and moistening to saturating, with the alcohol reflux of concentration cardinal principle 60%, filter and remove residue is 9-11 with medicinal liquid with strong aqua ammonia acid adjustment basicity to pH value, leaves standstill the back sucking filtration and gets precipitate;
(2) get Herba Apocyni veneti by proportioning,, behind the recovery ethanol, the medicinal liquid water-bath is concentrated into the thick paste shape with the alcohol reflux of concentration cardinal principle 70%, filter and remove residue;
(3) get Radix Stephaniae Tetrandrae, Ramulus Uncariae Cum Uncis pulverizing by proportioning, with the alcohol reflux of concentration cardinal principle 95%, put cold filter and remove residue separately or together, behind the recovery ethanol, the medicinal liquid water-bath is concentrated into the thick paste shape;
(4) get Spica Prunellae, Herba Dendrobii by proportioning,, behind the recovery ethanol, the medicinal liquid water-bath is concentrated into the thick paste shape with the alcohol reflux of concentration cardinal principle 30%, filter and remove residue;
(5) get Rhizoma Acori Graminei by proportioning, decocting extracts its volatile oil earlier, refilters and removes slag, and the medicinal liquid water-bath is concentrated into the thick paste shape;
(2) become cream:
(1) prepares substrate by rubber plaster substrate preparation method;
(2) each spice (comprising Rhizoma Acori Graminei volatile oil) that flow process operation () is extracted adds in the substrate, stirs;
(3) coating:, be final products of the present invention after the coating with the rubber plaster conventional method.
5, method according to claim 3 is characterized in that the usefulness strong aqua ammonia acid adjustment basicity in the said extract drugs operation (1), is to transfer to pH value to be roughly 10.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93111353 CN1091027A (en) | 1993-07-14 | 1993-07-14 | Blood-pressure reducing plaster sticking on acupoint and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 93111353 CN1091027A (en) | 1993-07-14 | 1993-07-14 | Blood-pressure reducing plaster sticking on acupoint and preparation method thereof |
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| Publication Number | Publication Date |
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| CN1091027A true CN1091027A (en) | 1994-08-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 93111353 Pending CN1091027A (en) | 1993-07-14 | 1993-07-14 | Blood-pressure reducing plaster sticking on acupoint and preparation method thereof |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1061256C (en) * | 1998-01-08 | 2001-01-31 | 王德波 | Hypertension ointment for external use |
| CN1068207C (en) * | 1996-03-11 | 2001-07-11 | 郭林根 | Cap for preventing and curing cerebral hemorrhage |
| CN102000187A (en) * | 2010-11-23 | 2011-04-06 | 淮南健科足疗用品有限公司 | Hypertension relieving traditional Chinese medicinal compound preparation and hypertension relieving insoles |
| CN101579482B (en) * | 2008-05-15 | 2011-04-20 | 北京北大维信生物科技有限公司 | Medicinal composition for treating hypertension and preparation method thereof |
| CN101579481B (en) * | 2008-05-15 | 2011-04-20 | 北京北大维信生物科技有限公司 | Medicinal composition for treating hypertension |
| CN101579480B (en) * | 2008-05-15 | 2011-06-29 | 北京北大维信生物科技有限公司 | Medicinal dripping pill for treating hypertension |
| CN102038795B (en) * | 2009-10-26 | 2012-05-23 | 天津中新药业集团股份有限公司达仁堂制药厂 | Detection method of five-nut demulcent pill as traditional Chinese medical preparation |
| CN102824489A (en) * | 2012-09-04 | 2012-12-19 | 王静 | Medicine for treating hypertension and preparation method for medicine |
| CN103055169A (en) * | 2012-02-27 | 2013-04-24 | 汪世龙 | External use plaster for treating hypertensive disease |
| CN103271506A (en) * | 2013-05-24 | 2013-09-04 | 海宇股份有限公司 | Depressurization healthcare shoe |
| CN109432381A (en) * | 2019-01-09 | 2019-03-08 | 山东盛宏医药科技有限公司 | A kind of acupoint hypotensive paste Chinese medicine and preparation method thereof |
-
1993
- 1993-07-14 CN CN 93111353 patent/CN1091027A/en active Pending
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1068207C (en) * | 1996-03-11 | 2001-07-11 | 郭林根 | Cap for preventing and curing cerebral hemorrhage |
| CN1061256C (en) * | 1998-01-08 | 2001-01-31 | 王德波 | Hypertension ointment for external use |
| CN101579482B (en) * | 2008-05-15 | 2011-04-20 | 北京北大维信生物科技有限公司 | Medicinal composition for treating hypertension and preparation method thereof |
| CN101579481B (en) * | 2008-05-15 | 2011-04-20 | 北京北大维信生物科技有限公司 | Medicinal composition for treating hypertension |
| CN101579480B (en) * | 2008-05-15 | 2011-06-29 | 北京北大维信生物科技有限公司 | Medicinal dripping pill for treating hypertension |
| CN102038795B (en) * | 2009-10-26 | 2012-05-23 | 天津中新药业集团股份有限公司达仁堂制药厂 | Detection method of five-nut demulcent pill as traditional Chinese medical preparation |
| CN102000187A (en) * | 2010-11-23 | 2011-04-06 | 淮南健科足疗用品有限公司 | Hypertension relieving traditional Chinese medicinal compound preparation and hypertension relieving insoles |
| CN103055169A (en) * | 2012-02-27 | 2013-04-24 | 汪世龙 | External use plaster for treating hypertensive disease |
| CN102824489A (en) * | 2012-09-04 | 2012-12-19 | 王静 | Medicine for treating hypertension and preparation method for medicine |
| CN103271506A (en) * | 2013-05-24 | 2013-09-04 | 海宇股份有限公司 | Depressurization healthcare shoe |
| CN103271506B (en) * | 2013-05-24 | 2015-10-28 | 海宇股份有限公司 | Health shoe for reducing bloodpressure |
| CN109432381A (en) * | 2019-01-09 | 2019-03-08 | 山东盛宏医药科技有限公司 | A kind of acupoint hypotensive paste Chinese medicine and preparation method thereof |
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