CN109078068A - A kind of cold drug and preparation method thereof - Google Patents

A kind of cold drug and preparation method thereof Download PDF

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Publication number
CN109078068A
CN109078068A CN201811258437.XA CN201811258437A CN109078068A CN 109078068 A CN109078068 A CN 109078068A CN 201811258437 A CN201811258437 A CN 201811258437A CN 109078068 A CN109078068 A CN 109078068A
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parts
radix
cold drug
cold
eupatorium
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何凤姣
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    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/11—Pteridophyta or Filicophyta (ferns)
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/68—Plantaginaceae (Plantain Family)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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Abstract

The invention discloses a kind of cold drugs, are made including the raw material below according to parts by weight: 20~30 parts of honeysuckle, 15~20 parts of Fructus Forsythiae, 10~15 parts of phoenix-tail fern, 10~15 parts of radix scutellariae, 5~10 parts of Radix Angelicae Sinensis, 1~10 part of eupatorium, 3~7 parts of Radix Glycyrrhizae, 2~6 parts of Asiatic plantain, 1~5 part of rhizome of chuanxiong, 1~5 part of cortex albiziae, 0.5~1 part of almond.The invention also discloses the preparation methods of the cold drug.Cold drug prepared by the present invention can effectively mitigate the symptom of flu, have therapeutic effect well for caused headache of catching a cold, dizzy and fever, this formula components is reasonable, and curative effect is clear, can effectively treat flu.

Description

A kind of cold drug and preparation method thereof
Technical field
The present invention relates to a kind of field of medicaments, specifically a kind of cold drug and preparation method thereof.
Background technique
Flu, the also known as infection of the upper respiratory tract.It is the general name for including nasal cavity, pharynx or acute throat inflammation.The upper sense of broad sense is not It is a medical diagnosis on disease, but one group of disease, including common cold, viral pharyngitis, laryngitis, herpangina, pharynx conjunctiva Heat, bacterial pharyngotonsillitis.The upper sense of narrow sense is also known as common cold, is the most common acute infections of respiratory tract disease, more In self limiting, but incidence is higher.Adult annual generation 2~4 times, children's incidence is higher, and annual 6~8 times.Whole year can all be sent out Disease, winter-spring season are more.
The drug for treating flu currently on the market is numerous, but price is somewhat expensive, and there are many effects of drug therapy flu simultaneously Undesirable, setting there is not effect substantially, takes many days all without effect, there are many more people because taking excessive medicine of the same race Object produces repellence to drug, therapeutic effect is caused further to decline.
Summary of the invention
The purpose of the present invention is to provide a kind of cold drugs and preparation method thereof, mentioned above in the background art to solve Problem.
To achieve the above object, the invention provides the following technical scheme:
A kind of cold drug, including below according to the raw material of parts by weight: 20~30 parts of honeysuckle, 15~20 parts of Fructus Forsythiae, phoenix-tail fern 10~15 parts, 10~15 parts of radix scutellariae, 5~10 parts of Radix Angelicae Sinensis, 1~10 part of eupatorium, 3~7 parts of Radix Glycyrrhizae, 2~6 parts of Asiatic plantain, rhizome of chuanxiong 1~ 5 parts, 1~5 part of cortex albiziae, 0.5~1 part of almond.
As a further solution of the present invention: including below according to the raw material of parts by weight: 23~27 parts of honeysuckle, Fructus Forsythiae 16~ 19 parts, 11~14 parts of phoenix-tail fern, 11~14 parts of radix scutellariae, 6~9 parts of Radix Angelicae Sinensis, 3~8 parts of eupatorium, 4~6 parts of Radix Glycyrrhizae, Asiatic plantain 3~5 Part, 2~4 parts of rhizome of chuanxiong, 1~5 part of cortex albiziae, 0.6~0.9 part of almond.
As the present invention further scheme: including below according to the raw material of parts by weight: 25 parts of honeysuckle, 17 parts of Fructus Forsythiae, 13 parts of phoenix-tail fern, 12 parts of radix scutellariae, 7 parts of Radix Angelicae Sinensis, 5 parts of eupatorium, 5 parts of Radix Glycyrrhizae, 4 parts of Asiatic plantain, 3 parts of rhizome of chuanxiong, 3 parts of cortex albiziae, almond 0.8 part.
The preparation method of the drug of the treatment flu, steps are as follows:
1) parts by weights also known as takes above-mentioned raw materials, and above-mentioned raw materials are put into clear water and rinse 4min；
2) honeysuckle, Fructus Forsythiae, phoenix-tail fern, radix scutellariae and Radix Angelicae Sinensis are extracted, extract is dried for standby；
3) eupatorium, Radix Glycyrrhizae, Asiatic plantain, rhizome of chuanxiong, cortex albiziae and almond are crushed, and pass through 50 mesh and 100 meshes respectively, choosing Herb in granule form sprills of the fetch bit between 50 mesh and 100 mesh, then these powder are placed in the drying box that temperature is 80 DEG C and are dried It is dry；
4) substance in step 2) and step 3) is merged, ethanol solution is added and produces into sense by 2 concentrations Emit the effective elements of the medicine；
5) effective component is taken, capsule, tablet and oral agents are made with auxiliary material appropriate.
As further scheme of the invention: the extraction time in the step 2) is 360min.
As further scheme of the invention: the temperature and times of 2 concentrations in the step 4) are respectively the 1st The temperature of secondary concentration is 80 DEG C, concentration time 60min, and the temperature of the 2nd concentration is 50 DEG C, concentration time 30min.
As further scheme of the invention: the auxiliary material in the step 5) includes one of sucrose and starch or two The mixing of person.
Compared with prior art, the beneficial effects of the present invention are: the drug for the treatment of flu prepared by the present invention can be effective Ground mitigates the symptom of flu, has therapeutic effect well for caused headache of catching a cold, dizzy and fever, this formula components is closed Reason, curative effect is clear, can effectively treat flu.
Specific embodiment
Technical solution of the present invention is described in more detail With reference to embodiment.
Embodiment 1
A kind of cold drug, including below according to the raw material of parts by weight: 20 parts of honeysuckle, 15 parts of Fructus Forsythiae, 10 parts of phoenix-tail fern, radix scutellariae 10 parts, 5 parts of Radix Angelicae Sinensis, 1 part of eupatorium, 3 parts of Radix Glycyrrhizae, 2 parts of Asiatic plantain, 1 part of rhizome of chuanxiong, 1 part of cortex albiziae, 0.5 part of almond.
In the present embodiment, the preparation method of the cold drug, steps are as follows:
1) parts by weights also known as takes above-mentioned raw materials, and above-mentioned raw materials are put into clear water and rinse 4min；
2) honeysuckle, Fructus Forsythiae, phoenix-tail fern, radix scutellariae and Radix Angelicae Sinensis are extracted, extract is dried for standby, and extraction time is 360min；
3) eupatorium, Radix Glycyrrhizae, Asiatic plantain, rhizome of chuanxiong, cortex albiziae and almond are crushed, and pass through 50 mesh and 100 meshes respectively, choosing Herb in granule form sprills of the fetch bit between 50 mesh and 100 mesh, then these powder are placed in the drying box that temperature is 80 DEG C and are dried It is dry；
4) substance in step 2) and step 3) is merged, ethanol solution is added and produces into sense by 2 concentrations The effective elements of the medicine is emitted, the temperature of the 1st concentration is 80 DEG C, concentration time 60min, and the temperature of the 2nd concentration is 50 DEG C, dense The contracting time is 30min；
5) effective component is taken, capsule, tablet and oral agents are made with auxiliary material appropriate, the auxiliary material includes sucrose and starch One or both of mixing.
Embodiment 2
A kind of cold drug, including below according to the raw material of parts by weight: 23 parts of honeysuckle, 16 parts of Fructus Forsythiae, 11 parts of phoenix-tail fern, radix scutellariae 11 parts, 6 parts of Radix Angelicae Sinensis, 3 parts of eupatorium, 4 parts of Radix Glycyrrhizae, 3 parts of Asiatic plantain, 2 parts of rhizome of chuanxiong, 1 part of cortex albiziae, 0.6 part of almond.
In the present embodiment, the preparation method of the cold drug, steps are as follows:
1) parts by weights also known as takes above-mentioned raw materials, and above-mentioned raw materials are put into clear water and rinse 4min；
2) honeysuckle, Fructus Forsythiae, phoenix-tail fern, radix scutellariae and Radix Angelicae Sinensis are extracted, extract is dried for standby, and extraction time is 360min；
3) eupatorium, Radix Glycyrrhizae, Asiatic plantain, rhizome of chuanxiong, cortex albiziae and almond are crushed, and pass through 50 mesh and 100 meshes respectively, choosing Herb in granule form sprills of the fetch bit between 50 mesh and 100 mesh, then these powder are placed in the drying box that temperature is 80 DEG C and are dried It is dry；
4) substance in step 2) and step 3) is merged, ethanol solution is added and produces into sense by 2 concentrations The effective elements of the medicine is emitted, the temperature of the 1st concentration is 80 DEG C, concentration time 60min, and the temperature of the 2nd concentration is 50 DEG C, dense The contracting time is 30min；
5) effective component is taken, capsule, tablet and oral agents are made with auxiliary material appropriate, the auxiliary material includes sucrose and starch One or both of mixing.
Embodiment 3
A kind of cold drug, including below according to the raw material of parts by weight: 25 parts of honeysuckle, 17 parts of Fructus Forsythiae, 13 parts of phoenix-tail fern, radix scutellariae 12 parts, 7 parts of Radix Angelicae Sinensis, 5 parts of eupatorium, 5 parts of Radix Glycyrrhizae, 4 parts of Asiatic plantain, 3 parts of rhizome of chuanxiong, 3 parts of cortex albiziae, 0.8 part of almond.
In the present embodiment, the preparation method of the cold drug, steps are as follows:
1) parts by weights also known as takes above-mentioned raw materials, and above-mentioned raw materials are put into clear water and rinse 4min；
2) honeysuckle, Fructus Forsythiae, phoenix-tail fern, radix scutellariae and Radix Angelicae Sinensis are extracted, extract is dried for standby, and extraction time is 360min；
3) eupatorium, Radix Glycyrrhizae, Asiatic plantain, rhizome of chuanxiong, cortex albiziae and almond are crushed, and pass through 50 mesh and 100 meshes respectively, choosing Herb in granule form sprills of the fetch bit between 50 mesh and 100 mesh, then these powder are placed in the drying box that temperature is 80 DEG C and are dried It is dry；
4) substance in step 2) and step 3) is merged, ethanol solution is added and produces into sense by 2 concentrations The effective elements of the medicine is emitted, the temperature of the 1st concentration is 80 DEG C, concentration time 60min, and the temperature of the 2nd concentration is 50 DEG C, dense The contracting time is 30min；
5) effective component is taken, capsule, tablet and oral agents are made with auxiliary material appropriate, the auxiliary material includes sucrose and starch One or both of mixing.
Embodiment 4
A kind of cold drug, including below according to the raw material of parts by weight: 30 parts of honeysuckle, 20 parts of Fructus Forsythiae, 15 parts of phoenix-tail fern, radix scutellariae 15 parts, 10 parts of Radix Angelicae Sinensis, 10 parts of eupatorium, 7 parts of Radix Glycyrrhizae, 6 parts of Asiatic plantain, 5 parts of rhizome of chuanxiong, 5 parts of cortex albiziae, 1 part of almond.
In the present embodiment, the preparation method of the cold drug, steps are as follows:
1) parts by weights also known as takes above-mentioned raw materials, and above-mentioned raw materials are put into clear water and rinse 4min；
2) honeysuckle, Fructus Forsythiae, phoenix-tail fern, radix scutellariae and Radix Angelicae Sinensis are extracted, extract is dried for standby, and extraction time is 360min；
3) eupatorium, Radix Glycyrrhizae, Asiatic plantain, rhizome of chuanxiong, cortex albiziae and almond are crushed, and pass through 50 mesh and 100 meshes respectively, choosing Herb in granule form sprills of the fetch bit between 50 mesh and 100 mesh, then these powder are placed in the drying box that temperature is 80 DEG C and are dried It is dry；
4) substance in step 2) and step 3) is merged, ethanol solution is added and produces into sense by 2 concentrations The effective elements of the medicine is emitted, the temperature of the 1st concentration is 80 DEG C, concentration time 60min, and the temperature of the 2nd concentration is 50 DEG C, dense The contracting time is 30min；
5) effective component is taken, capsule, tablet and oral agents are made with auxiliary material appropriate, the auxiliary material includes sucrose and starch One or both of mixing.
Embodiment 5
A kind of cold drug, including below according to the raw material of parts by weight: 27 parts of honeysuckle, 19 parts of Fructus Forsythiae, 14 parts of phoenix-tail fern, radix scutellariae 14 parts, 9 parts of Radix Angelicae Sinensis, 8 parts of eupatorium, 6 parts of Radix Glycyrrhizae, 5 parts of Asiatic plantain, 4 parts of rhizome of chuanxiong, 5 parts of cortex albiziae, 0.9 part of almond.
In the present embodiment, the preparation method of the cold drug, steps are as follows:
1) parts by weights also known as takes above-mentioned raw materials, and above-mentioned raw materials are put into clear water and rinse 4min；
2) honeysuckle, Fructus Forsythiae, phoenix-tail fern, radix scutellariae and Radix Angelicae Sinensis are extracted, extract is dried for standby, and extraction time is 360min；
3) eupatorium, Radix Glycyrrhizae, Asiatic plantain, rhizome of chuanxiong, cortex albiziae and almond are crushed, and pass through 50 mesh and 100 meshes respectively, choosing Herb in granule form sprills of the fetch bit between 50 mesh and 100 mesh, then these powder are placed in the drying box that temperature is 80 DEG C and are dried It is dry；
4) substance in step 2) and step 3) is merged, ethanol solution is added and produces into sense by 2 concentrations The effective elements of the medicine is emitted, the temperature of the 1st concentration is 80 DEG C, concentration time 60min, and the temperature of the 2nd concentration is 50 DEG C, dense The contracting time is 30min；
5) effective component is taken, capsule, tablet and oral agents are made with auxiliary material appropriate, the auxiliary material includes sucrose and starch One or both of mixing.
Embodiment 6
A kind of cold drug, including below according to the raw material of parts by weight: 22 parts of honeysuckle, 18 parts of Fructus Forsythiae, 11 parts of phoenix-tail fern, radix scutellariae 12 parts, 7 parts of Radix Angelicae Sinensis, 4 parts of eupatorium, 6 parts of Radix Glycyrrhizae, 3 parts of Asiatic plantain, 2 parts of rhizome of chuanxiong, 3 parts of cortex albiziae, 0.6 part of almond.
In the present embodiment, the preparation method of the cold drug, steps are as follows:
1) parts by weights also known as takes above-mentioned raw materials, and above-mentioned raw materials are put into clear water and rinse 4min；
2) honeysuckle, Fructus Forsythiae, phoenix-tail fern, radix scutellariae and Radix Angelicae Sinensis are extracted, extract is dried for standby, and extraction time is 360min；
3) eupatorium, Radix Glycyrrhizae, Asiatic plantain, rhizome of chuanxiong, cortex albiziae and almond are crushed, and pass through 50 mesh and 100 meshes respectively, choosing Herb in granule form sprills of the fetch bit between 50 mesh and 100 mesh, then these powder are placed in the drying box that temperature is 80 DEG C and are dried It is dry；
4) substance in step 2) and step 3) is merged, ethanol solution is added and produces into sense by 2 concentrations The effective elements of the medicine is emitted, the temperature of the 1st concentration is 80 DEG C, concentration time 60min, and the temperature of the 2nd concentration is 50 DEG C, dense The contracting time is 30min；
5) effective component is taken, capsule, tablet and oral agents are made with auxiliary material appropriate, the auxiliary material includes sucrose and starch One or both of mixing.
Illustrate application effect of the invention below by way of practical example:
1) 350 cold patients are chosen, male 100, women 100, average age was at 35 years old；Symptom is dizzy, head Pain fever, acpuei pharyngitis and viral pharyngitis；
2) 350 patients being divided into seven groups, every group of 50 people take the cold drug prepared in Examples 1 to 6 respectively, and the 7th group Take White Cloud Mountain QINGKAILING JIAONANG；
3) usage and dosage: taking 3 times for each person every day, drink before the meal, and continuous oral 3 days；
4) it curative effect: is formulated referring to " traditional Chinese medicine Clinical Researches of New Drugs guideline "；
Effective: flu is completely good.Without dizzy, headache and pharyngalgia symptom；Effect is unobvious: with slight dizzy, headache With pharyngalgia phenomenon；
5) the experimental results are shown inthe following table:
As can be known from the above table, patient is after taking cold drug of the invention, and effective percentage has reached 98%, and during treatment Apparent bad phenomenon is not observed, illustrates that cold drug prepared by the present invention can effectively treat flu, and treat flu Effect it is very good.
Better embodiment of the invention is explained in detail above, but the present invention is not limited to above-mentioned embodiment party Formula within the knowledge of one of ordinary skill in the art can also be without departing from the purpose of the present invention Various changes can be made.

Claims (7)

1. a kind of cold drug, which is characterized in that including below according to the raw material of parts by weight: 20~30 parts of honeysuckle, Fructus Forsythiae 15~20 Part, 10~15 parts of phoenix-tail fern, 10~15 parts of radix scutellariae, 5~10 parts of Radix Angelicae Sinensis, 1~10 part of eupatorium, 3~7 parts of Radix Glycyrrhizae, Asiatic plantain 2~6 Part, 1~5 part of rhizome of chuanxiong, 1~5 part of cortex albiziae, 0.5~1 part of almond.
2. cold drug according to claim 1, which is characterized in that including below according to the raw material of parts by weight: honeysuckle 23~ 27 parts, 16~19 parts of Fructus Forsythiae, 11~14 parts of phoenix-tail fern, 11~14 parts of radix scutellariae, 6~9 parts of Radix Angelicae Sinensis, 3~8 parts of eupatorium, Radix Glycyrrhizae 4~6 Part, 3~5 parts of Asiatic plantain, 2~4 parts of rhizome of chuanxiong, 1~5 part of cortex albiziae, 0.6~0.9 part of almond.
3. cold drug according to claim 2, which is characterized in that including below according to the raw material of parts by weight: 25 parts of honeysuckle, 17 parts of Fructus Forsythiae, 13 parts of phoenix-tail fern, 12 parts of radix scutellariae, 7 parts of Radix Angelicae Sinensis, 5 parts of eupatorium, 5 parts of Radix Glycyrrhizae, 4 parts of Asiatic plantain, 3 parts of rhizome of chuanxiong, cortex albiziae 3 parts, 0.8 part of almond.
4. a kind of preparation method of cold drug a method according to any one of claims 1-3, which is characterized in that steps are as follows:
1) parts by weights also known as takes above-mentioned raw materials, and above-mentioned raw materials are put into clear water and rinse 4min；
2) honeysuckle, Fructus Forsythiae, phoenix-tail fern, radix scutellariae and Radix Angelicae Sinensis are extracted, extract is dried for standby；
3) eupatorium, Radix Glycyrrhizae, Asiatic plantain, rhizome of chuanxiong, cortex albiziae and almond are crushed, and pass through 50 mesh and 100 meshes respectively, choose position Herb in granule form sprills between 50 mesh and 100 mesh, then these powder are placed in the drying box that temperature is 80 DEG C and are dried；
4) substance in step 2) and step 3) is merged, ethanol solution is added and produces into cold drug by 2 concentrations Effective component；
5) effective component is taken, capsule, tablet and oral agents are made with auxiliary material appropriate.
5. the preparation method of cold drug according to claim 4, which is characterized in that the extraction time in the step 2) is 360min。
6. the preparation method of cold drug according to claim 4, which is characterized in that 2 times in the step 4) concentrations Temperature and time is respectively that the temperature of the 1st concentration is 80 DEG C, concentration time 60min, and the temperature of the 2nd concentration is 50 DEG C, Concentration time is 30min.
7. the preparation method of cold drug according to claim 4, which is characterized in that the auxiliary material in the step 5) includes sugarcane The mixing of one or both of sugar and starch.
CN201811258437.XA 2018-10-26 2018-10-26 A kind of cold drug and preparation method thereof Withdrawn CN109078068A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1430984A (en) * 2003-01-04 2003-07-23 辽宁中医学院 Detoxification capsule and its prodn. methods
CN103768156A (en) * 2012-10-22 2014-05-07 姜亭伊 Cold treating medicine and preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1430984A (en) * 2003-01-04 2003-07-23 辽宁中医学院 Detoxification capsule and its prodn. methods
CN103768156A (en) * 2012-10-22 2014-05-07 姜亭伊 Cold treating medicine and preparation method

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