CN109077318A - A kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food - Google Patents
A kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food Download PDFInfo
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- CN109077318A CN109077318A CN201810989786.2A CN201810989786A CN109077318A CN 109077318 A CN109077318 A CN 109077318A CN 201810989786 A CN201810989786 A CN 201810989786A CN 109077318 A CN109077318 A CN 109077318A
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- 239000000284 extract Substances 0.000 title claims abstract description 138
- 240000004507 Abelmoschus esculentus Species 0.000 title claims abstract description 115
- 235000003934 Abelmoschus esculentus Nutrition 0.000 title claims abstract description 84
- 235000013305 food Nutrition 0.000 title claims abstract description 35
- 230000002218 hypoglycaemic effect Effects 0.000 title claims abstract description 33
- 208000013016 Hypoglycemia Diseases 0.000 title claims abstract description 30
- 238000000605 extraction Methods 0.000 claims abstract description 55
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- 244000189799 Asimina triloba Species 0.000 claims abstract description 32
- 235000006264 Asimina triloba Nutrition 0.000 claims abstract description 32
- 235000009467 Carica papaya Nutrition 0.000 claims abstract description 32
- 235000011430 Malus pumila Nutrition 0.000 claims abstract description 32
- 235000015103 Malus silvestris Nutrition 0.000 claims abstract description 32
- 244000046146 Pueraria lobata Species 0.000 claims abstract description 32
- 235000010575 Pueraria lobata Nutrition 0.000 claims abstract description 32
- 239000007788 liquid Substances 0.000 claims abstract description 24
- 238000001035 drying Methods 0.000 claims abstract description 18
- 239000000463 material Substances 0.000 claims abstract description 14
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- 240000004244 Cucurbita moschata Species 0.000 claims abstract description 12
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- 238000010438 heat treatment Methods 0.000 claims description 23
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- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 5
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- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 6
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- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
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- 229920002488 Hemicellulose Polymers 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
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- 241001465754 Metazoa Species 0.000 description 1
- 244000302512 Momordica charantia Species 0.000 description 1
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- 206010028980 Neoplasm Diseases 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 244000061458 Solanum melongena Species 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
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- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
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- 108091005995 glycated hemoglobin Proteins 0.000 description 1
- 230000002641 glycemic effect Effects 0.000 description 1
- 230000003345 hyperglycaemic effect Effects 0.000 description 1
- 201000001421 hyperglycemia Diseases 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
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- VUZPPFZMUPKLLV-UHFFFAOYSA-N methane;hydrate Chemical compound C.O VUZPPFZMUPKLLV-UHFFFAOYSA-N 0.000 description 1
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- 230000012666 negative regulation of transcription by glucose Effects 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
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- 239000011664 nicotinic acid Substances 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
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- 102000004169 proteins and genes Human genes 0.000 description 1
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- 229910052711 selenium Inorganic materials 0.000 description 1
- 230000036299 sexual function Effects 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
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- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Botany (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Preparation Of Fruits And Vegetables (AREA)
Abstract
The present invention relates to a kind of health foods, more particularly to a kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food, the present invention extracts from okra by screening, extraction, separation of solid and liquid, concentration, drying and other steps and obtains blood sugar reducing component, and this is obtained through refining into, hypoglycemia healthcare food is made, which includes 50~80 parts of Abelmoschus Esculentus Linn extracts；10~20 parts of mulberry-leaf extracts；10~20 parts of Bitter Melon P.Es；5-10 parts of squash polyoses；3-7 parts of apple grains；3-7 parts of pawpaw grains；3-7 parts of pueraria lobata grains；5~20 parts of auxiliary materials；These weight items are mixed according to the proportion, are obtained after granulation, whole grain, tabletting and packaging, not only technology is simple by the present invention, industrialization production may be implemented, and blood sugar decreasing effect is obvious, has expanded the application range of okra significantly.
Description
Technical field
The present invention relates to a kind of health food, in particular to a kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food.
Background technique
Okra (Abelmoschus esculentus) alias gumbo, swordweed.List is in terms of fruit pod color, and can share out bonus color
With 2 kinds of green.Since dark green kind meat is preferable, consumption, ornamental value are strong, are quite favored；Opposite aubergine kind meat then compared with
Difference should not be selected in terms of edible angle.General okra length is 5~10cm, elongated quite like the finger of people.American and Britain, method, day
Equal states are all included in it among new century best green food register, are a kind of new type of health vegetables with better nutritivity value
Dish.
Okra various pieces all contain hemicellulose, cellulose and lignin.Okra fruit protein rich in dissociates
Amino acid, VC、VA、VEWith the mineral elements such as phosphorus, iron, potassium, calcium, zinc, manganese and the stickum being made of pectin and polysaccharide etc..
In every 100g okra fruit containing 2.5g protein, 0.1g fat, carbon water 2.7g compound, 3.9g crude fibre, 0.2mg vitamin B1,
0.06mg vitamin B2,44mg vitamin C, 1.03mg vitamin E, l.0mg nicotinic acid, 95mg mineral nutrition potassium, 45mg calcium,
65mg phosphorus, 29mg magnesium.Due to kind difference, the content of each ingredient also can difference.The healthy nutritive value of okra is very
Height, such as: the vitamin A in okra can effectively protect retina, it is ensured that good eyesight prevents the generation of cataract；Fruit
The stickum of the compositions such as glue and polysaccharide has human body and promotes gastrointestinal peristalsis, prevents the health-care effects such as constipation, and appropriate more foods can
Enhancing sexual function can also enhance the endurance of human body；In addition okra low fat, low sugar, can be used as diet food；Since it contains
Human body cancer-resisting ability can be enhanced in zinc and selenium and other trace elements；Its hair that can prevent cardiovascular disease rich in vitamin C
It is raw, immunity, while the combination of vitamin C abundant and Soluble Fiber (pectin) are improved, is had to skin certain mild
Protective effect, can replace the skincare product of some chemistry；Soluble Fiber can promote the excretion of internal organic substance, reduce
The accumulation of toxin in vivo reduces cholesterol level.
For the application value for further excavating okra, the present invention screened by okra, extraction, is separated by solid-liquid separation, concentration,
Drying and other steps are extracted from okra and obtain blood sugar reducing component, and the extract is applied to hypoglycemic product field, are made
Hypoglycemia healthcare food, blood sugar decreasing effect are obvious；Not only technology is simple by the present invention, and industrialization production may be implemented, and
The application range of okra has been expanded significantly.
Summary of the invention
In order to overcome the above-mentioned deficiencies of the prior art, the invention proposes a kind of Abelmoschus Esculentus Linn extract Hyperglycemic health care foods
Product, not only preparation process is simple, industrialization easy to accomplish, and blood sugar decreasing effect is good, and that has expanded okra significantly applies model
It encloses.
To achieve the goals above, the technical scheme adopted by the invention is that:
A kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food, the ingredient including following parts by weight:
50~80 parts of Abelmoschus Esculentus Linn extract；10~20 parts of mulberry-leaf extract；10~20 parts of Bitter Melon P.E；Squash polyoses 5-
10 parts；3-7 parts of apple grain；3-7 parts of pawpaw grain；3-7 parts of pueraria lobata grain；5~20 parts of auxiliary material.
Preferably, a kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food, the ingredient including following parts by weight:
70 parts of Abelmoschus Esculentus Linn extract；15 parts of mulberry-leaf extract；15 parts of Bitter Melon P.E；7 parts of squash polyoses；5 parts of apple grain；
5 parts of pawpaw grain；5 parts of pueraria lobata grain；10 parts of auxiliary material.
Preferably, the extracting method of the mulberry-leaf extract are as follows: by dried mulberry leaf powder essence, 50% ethyl alcohol of 3 times of volumes is added,
Soaking at room temperature 12h is placed in 60 DEG C of warm water and extracts 2h, and during which every 30min clock concussion mixes primary, then with 4200r/min
Revolving speed be centrifuged 30min, retain supernatant, finally supernatant is placed under the conditions of 60 DEG C and is condensed into dry powder, to dry powder by grinding after
Obtain mulberry-leaf extract；The extracting method of the Bitter Melon P.E are as follows: fresh bitter is cleaned up, fritter is cut into, and
Remove seed, add the water of 1.5 times of volumes, squeezed the juice with juice extractor, obtained juicing is placed on 0 DEG C by 200 mesh filter-cloth filterings
Under the conditions of stand 12h, supernatant is finally placed under the conditions of 60 DEG C and is condensed into dry powder and obtains balsam pear extraction by then Aspirate supernatant
Object.
Preferably, the extracting method of the squash polyoses are as follows: pumpkin is cut into small pieces, is added water to submerge, is squeezed the juice with juice extractor,
Obtained juicing is kept the temperature into 30min under the conditions of 70 DEG C, is then filtered and retains filtrate, filtrate is carried out under the conditions of 80 DEG C
95% alcohol of 5 times of volumes is added after vacuum concentration, is stood overnight in 4 DEG C of refrigerators after uniform stirring, in finally centrifugation removal
Clear liquid, remaining sediment are squash polyoses.
Preferably, the Abelmoschus Esculentus Linn extract is extracted using fresh gumbo or dry gumbo, and the auxiliary material is microcrystalline cellulose
At least one of element, magnesium stearate, sodium alginate and pregelatinized starch.
Preferably, the Abelmoschus Esculentus Linn extract extraction process the following steps are included:
S1, it is extracted after being screened, cleaned, crushed or being sliced to okra added with solvent, wherein crushing is needle
To mode used by dry okra, slice is mode used by being directed to cadmium yellow gumbo,
After S2, extraction, extracting solution is obtained through being separated by solid-liquid separation, using 80 mesh filter screen filtration extracting solutions, using tripodia
Formula centrifuge continues to dry residue, combined extract；
S3, extracting solution obtained in S2 step is concentrated, obtains Abelmoschus Esculentus Linn extract after dry.
It is furthermore preferred that the organic solvent is pure organic solvent or mixed organic solvents, the pure organic solvent is 100%
One of methanol and 100% ethyl alcohol, the mixed organic solvents are that pure organic solvent is mixed with water, described to be mixed with
The composition ratio of solvent are as follows: pure organic solvent: water=0.3~1:1；The volume of the organic solvent and the weight of cadmium yellow gumbo
Be 10:1~30:1, the weight of the volume of the organic solvent and dry okra is 15:1~25:1.
It is furthermore preferred that the extracting mode in the S1 step is appointing in heating extraction, ultrasonic wave extraction and Microwave Extraction
It anticipates one kind, the Extracting temperature of the heating extraction is 70~85 DEG C, 2~3h of extraction time；The power of the ultrasonic wave extraction is
150~180W/L, extraction time are 2~2.5h；The power of the Microwave Extraction be 200~500W/L, extraction time be 3~
4h。
It is furthermore preferred that the condensing mode in the S3 step is vacuum-concentrcted, the temperature of the vacuum-concentrcted
It is 60~80 DEG C.
It is furthermore preferred that the drying mode in the S3 step is in vacuum drying, blast heating drying and ultrasonic wave drying
Any one, the vacuum drying heating temperature be 50~60 DEG C；The dry heating temperature of the blast heating is 40~
50℃；The dry power of the ultrasonic wave is 10~100W/cm2, drying temperature is 20~30 DEG C.
Compared with prior art, the beneficial effects of the present invention are:
The present invention by screening, extraction, be separated by solid-liquid separation, concentration, drying and other steps extracted from okra obtain it is hypoglycemic
Ingredient, and the extract is applied to hypoglycemic product field, by the way that other have drop with mulberry-leaf extract, Bitter Melon P.E etc.
The substance or auxiliary material of blood glucose effect are reasonably combined, and hypoglycemia healthcare food is made in scientific compatibility, achieve apparent effect of reducing blood sugar
Fruit；Not only technology is simple by the present invention, and industrialization production may be implemented, and has expanded the application range of okra significantly.
Specific embodiment
Specific embodiments of the present invention will be further explained below.It should be noted that for these implementations
The explanation of mode is used to help understand the present invention, but and does not constitute a limitation of the invention.In addition, invention described below
Technical characteristic involved in each embodiment can be combined with each other as long as they do not conflict with each other.
Embodiment 1:
A kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food, the ingredient including following parts by weight:
50 parts of Abelmoschus Esculentus Linn extract；10 parts of mulberry-leaf extract；10 parts of Bitter Melon P.E；5 parts of squash polyoses；3 parts of apple grain；
3 parts of pawpaw grain；3 parts of pueraria lobata grain；5 parts of sodium alginate.
Above-mentioned weight item is mixed according to the proportion, finished product can be obtained after granulation, whole grain, tabletting and packaging.
Wherein, the extracting method of mulberry-leaf extract are as follows: by dried mulberry leaf powder essence, 50% ethyl alcohol of 3 times of volumes, room temperature leaching is added
Bubble 12h, which is placed in 60 DEG C of warm water, extracts 2h, and during which every 30min clock concussion mixes primary, is then turned with 4200r/min
Speed centrifugation 30min, retains supernatant, finally supernatant is placed under the conditions of 60 DEG C and is condensed into dry powder, obtains after grinding to dry powder
Mulberry-leaf extract；
The extracting method of Bitter Melon P.E are as follows: fresh bitter is cleaned up, fritter is cut into, and remove seed, adds
The water of 1.5 times of volumes, is squeezed the juice with juice extractor, and obtained juicing is placed under the conditions of 0 DEG C by 200 mesh filter-cloth filterings and is stood
Supernatant is finally placed in and is condensed into dry powder under the conditions of 60 DEG C and obtains Bitter Melon P.E by 12h, then Aspirate supernatant.
The extracting method of squash polyoses are as follows: pumpkin is cut into small pieces, is added water to submerge, is squeezed the juice with juice extractor, the squeezing that will be obtained
Juice keeps the temperature 30min under the conditions of 70 DEG C, is then filtered and retains filtrate, be concentrated in vacuo under the conditions of 80 DEG C to filtrate
95% alcohol of 5 times of volumes is added afterwards, is stood overnight in 4 DEG C of refrigerators after uniform stirring, finally centrifugation removal supernatant remains
Under sediment be squash polyoses.
The production method of apple grain, pawpaw grain and pueraria lobata grain are as follows: fresh intact apple, pawpaw and pueraria lobata are chosen respectively,
After cleaning up they are cut into bulk respectively, are subsequently placed in 50 DEG C of environment and are dried, (water after drying process
Point content is 20% or so) they are put into crushing and pelletizing machine respectively 2 × 2mm~5 × 5mm size particle is made.
The extraction process of Abelmoschus Esculentus Linn extract the following steps are included:
S1, pulverization process is carried out to it after screening the impurity such as the intact dry okra of 100kg, removal dry leaves therein,
Then 30% ethyl alcohol is added to extract, the ratio between the volume of added 30% ethyl alcohol and dry gumbo weight is 25:1
(weight kg: volume L)；Extracting mode uses ultrasonic extraction, ultrasonic power 150W/L, extraction time 2h；
After S2, extraction, extracting solution is obtained through being separated by solid-liquid separation, using 80 mesh filter screen filtration extracting solutions, using tripodia
Formula centrifuge continues to dry residue, combined extract；
S3, said extracted liquid is concentrated, condensing mode is vacuum-concentrcted, wherein the control of vacuum-concentrcted temperature
Then system is dried concentrate in such a way that blast heating is dry at 60 DEG C, be 40 DEG C by heating and temperature control, obtain
To Abelmoschus Esculentus Linn extract, extract weight 3.1kg.
Embodiment 2:
A kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food, the ingredient including following parts by weight:
50 parts of Abelmoschus Esculentus Linn extract；10 parts of mulberry-leaf extract；10 parts of Bitter Melon P.E；5 parts of squash polyoses；3 parts of apple grain；
3 parts of pawpaw grain；3 parts of pueraria lobata grain；5 parts of sodium alginate.
Above-mentioned weight item is mixed according to the proportion, finished product can be obtained after granulation, whole grain, tabletting and packaging.
Wherein, the extracting method of mulberry-leaf extract are as follows: by dried mulberry leaf powder essence, 50% ethyl alcohol of 3 times of volumes, room temperature leaching is added
Bubble 12h, which is placed in 60 DEG C of warm water, extracts 2h, and during which every 30min clock concussion mixes primary, is then turned with 4200r/min
Speed centrifugation 30min, retains supernatant, finally supernatant is placed under the conditions of 60 DEG C and is condensed into dry powder, obtains after grinding to dry powder
Mulberry-leaf extract；
The extracting method of Bitter Melon P.E are as follows: fresh bitter is cleaned up, fritter is cut into, and remove seed, adds
The water of 1.5 times of volumes, is squeezed the juice with juice extractor, and obtained juicing is placed under the conditions of 0 DEG C by 200 mesh filter-cloth filterings and is stood
Supernatant is finally placed in and is condensed into dry powder under the conditions of 60 DEG C and obtains Bitter Melon P.E by 12h, then Aspirate supernatant.
The extracting method of squash polyoses are as follows: pumpkin is cut into small pieces, is added water to submerge, is squeezed the juice with juice extractor, the squeezing that will be obtained
Juice keeps the temperature 30min under the conditions of 70 DEG C, filtrate is then filtered and retains, after being concentrated in vacuo under the conditions of 80 DEG C to filtrate
95% alcohol of 5 times of volumes is added, is stood overnight in 4 DEG C of refrigerators after uniform stirring, finally centrifugation removal supernatant is left
Sediment be squash polyoses.
The production method of apple grain, pawpaw grain and pueraria lobata grain are as follows: fresh intact apple, pawpaw and pueraria lobata are chosen respectively,
After cleaning up they are cut into bulk respectively, are subsequently placed in 50 DEG C of environment and are dried, (water after drying process
Point content is 20% or so) they are put into crushing and pelletizing machine respectively 2 × 2mm~5 × 5mm size particle is made.
The extraction process of Abelmoschus Esculentus Linn extract the following steps are included:
S1, pulverization process is carried out to it after screening the impurity such as the intact dry okra of 100kg, removal dry leaves therein,
Then 60% ethyl alcohol is added to extract, the ratio between the volume of added 60% ethyl alcohol and dry gumbo weight is 20:1
(weight kg: volume L)；Extracting mode uses ultrasonic extraction, ultrasonic power 165W/L, extraction time 2.3h；
After S2, extraction, extracting solution is obtained through being separated by solid-liquid separation, using 80 mesh filter screen filtration extracting solutions, using tripodia
Formula centrifuge continues to dry residue, combined extract；
S3, said extracted liquid is concentrated, condensing mode is vacuum-concentrcted, wherein the control of vacuum-concentrcted temperature
Then system is dried concentrate in such a way that blast heating is dry at 70 DEG C, be 45 DEG C by heating and temperature control, obtain
Abelmoschus Esculentus Linn extract, extract weight 3.3kg.
Embodiment 3:
A kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food, the ingredient including following parts by weight:
50 parts of Abelmoschus Esculentus Linn extract；10 parts of mulberry-leaf extract；10 parts of Bitter Melon P.E；5 parts of squash polyoses；3 parts of apple grain；
3 parts of pawpaw grain；3 parts of pueraria lobata grain；5 parts of sodium alginate.
Above-mentioned weight item is mixed according to the proportion, finished product can be obtained after granulation, whole grain, tabletting and packaging.
Wherein, the extracting method of mulberry-leaf extract are as follows: by dried mulberry leaf powder essence, 50% ethyl alcohol of 3 times of volumes, room temperature leaching is added
Bubble 12h, which is placed in 60 DEG C of warm water, extracts 2h, and during which every 30min clock concussion mixes primary, is then turned with 4200r/min
Speed centrifugation 30min, retains supernatant, finally supernatant is placed under the conditions of 60 DEG C and is condensed into dry powder, obtains after grinding to dry powder
Mulberry-leaf extract；
The extracting method of Bitter Melon P.E are as follows: fresh bitter is cleaned up, fritter is cut into, and remove seed, adds
The water of 1.5 times of volumes, is squeezed the juice with juice extractor, and obtained juicing is placed under the conditions of 0 DEG C by 200 mesh filter-cloth filterings and is stood
Supernatant is finally placed in and is condensed into dry powder under the conditions of 60 DEG C and obtains Bitter Melon P.E by 12h, then Aspirate supernatant.
The extracting method of squash polyoses are as follows: pumpkin is cut into small pieces, is added water to submerge, is squeezed the juice with juice extractor, the squeezing that will be obtained
Juice keeps the temperature 30min under the conditions of 70 DEG C, is then filtered and retains filtrate, be concentrated in vacuo under the conditions of 80 DEG C to filtrate
95% alcohol of 5 times of volumes is added afterwards, is stood overnight in 4 DEG C of refrigerators after uniform stirring, finally centrifugation removal supernatant remains
Under sediment be squash polyoses.
The production method of apple grain, pawpaw grain and pueraria lobata grain are as follows: fresh intact apple, pawpaw and pueraria lobata are chosen respectively,
After cleaning up they are cut into bulk respectively, are subsequently placed in 50 DEG C of environment and are dried, (water after drying process
Point content is 20% or so) they are put into crushing and pelletizing machine respectively 2 × 2mm~5 × 5mm size particle is made.
The extraction process of Abelmoschus Esculentus Linn extract the following steps are included:
S1, pulverization process is carried out to it after screening the impurity such as the intact dry okra of 100kg, removal dry leaves therein,
Then 100% ethyl alcohol (not aqueous) is added to extract, the ratio between the volume of added 100% ethyl alcohol and dry gumbo weight
Example is 15:1 (weight kg: volume L)；Extracting mode uses ultrasonic extraction, ultrasonic power 180W/L, extraction time 2.5h；
After S2, extraction, extracting solution is obtained through being separated by solid-liquid separation, using 80 mesh filter screen filtration extracting solutions, using tripodia
Formula centrifuge continues to dry residue, combined extract；
S3, said extracted liquid is concentrated, condensing mode is vacuum-concentrcted, wherein the control of vacuum-concentrcted temperature
Then system is dried concentrate in such a way that blast heating is dry at 70 DEG C, be 50 DEG C by heating and temperature control, obtain
To Abelmoschus Esculentus Linn extract, extract weight 3.15kg.
Embodiment 4:
A kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food, the ingredient including following parts by weight:
70 parts of Abelmoschus Esculentus Linn extract；15 parts of mulberry-leaf extract；15 parts of Bitter Melon P.E；7 parts of squash polyoses；5 parts of apple grain；
5 parts of pawpaw grain；5 parts of pueraria lobata grain；Auxiliary material be (mixture of magnesium stearate and pregelatinized starch, magnesium stearate and pregelatinized starch
Weight ratio is 1:1) 10 parts.
Above-mentioned weight item is mixed according to the proportion, finished product can be obtained after granulation, whole grain, tabletting and packaging.
Wherein, the extracting method of mulberry-leaf extract are as follows: by dried mulberry leaf powder essence, 50% ethyl alcohol of 3 times of volumes, room temperature leaching is added
Bubble 12h, which is placed in 60 DEG C of warm water, extracts 2h, and during which every 30min clock concussion mixes primary, is then turned with 4200r/min
Speed centrifugation 30min, retains supernatant, finally supernatant is placed under the conditions of 60 DEG C and is condensed into dry powder, obtains after grinding to dry powder
Mulberry-leaf extract；
The extracting method of Bitter Melon P.E are as follows: fresh bitter is cleaned up, fritter is cut into, and remove seed, adds
The water of 1.5 times of volumes, is squeezed the juice with juice extractor, and obtained juicing is placed under the conditions of 0 DEG C by 200 mesh filter-cloth filterings and is stood
Supernatant is finally placed in and is condensed into dry powder under the conditions of 60 DEG C and obtains Bitter Melon P.E by 12h, then Aspirate supernatant.
The extracting method of squash polyoses are as follows: pumpkin is cut into small pieces, is added water to submerge, is squeezed the juice with juice extractor, the squeezing that will be obtained
Juice keeps the temperature 30min under the conditions of 70 DEG C, is then filtered and retains filtrate, be concentrated in vacuo under the conditions of 80 DEG C to filtrate
95% alcohol of 5 times of volumes is added afterwards, is stood overnight in 4 DEG C of refrigerators after uniform stirring, finally centrifugation removal supernatant remains
Under sediment be squash polyoses.
The production method of apple grain, pawpaw grain and pueraria lobata grain are as follows: fresh intact apple, pawpaw and pueraria lobata are chosen respectively,
After cleaning up they are cut into bulk respectively, are subsequently placed in 50 DEG C of environment and are dried, (water after drying process
Point content is 20% or so) they are put into crushing and pelletizing machine respectively 2 × 2mm~5 × 5mm size particle is made.
The extraction process of Abelmoschus Esculentus Linn extract the following steps are included:
S1, pulverization process is carried out to it after screening the impurity such as the intact dry okra of 100kg, removal dry leaves therein,
Then 70% methanol is added to extract, the ratio between the volume of added 70% methanol and dry gumbo weight is 18:1
(weight kg: volume L)；Extracting mode uses heating extraction；Extracting temperature is 70 DEG C；Extraction time is 2h；
After S2, extraction, extracting solution is obtained through being separated by solid-liquid separation, using 80 mesh filter screen filtration extracting solutions, using tripodia
Formula centrifuge continues to dry residue, combined extract；
S3, said extracted liquid is concentrated, condensing mode is vacuum-concentrcted, wherein the control of vacuum-concentrcted temperature
Then system is dried concentrate using vacuum drying mode at 60 DEG C, be 50 DEG C by heating and temperature control, obtain Huang
Gumbo extract, extract weight 3.9kg.
Embodiment 5:
A kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food, the ingredient including following parts by weight:
70 parts of Abelmoschus Esculentus Linn extract；15 parts of mulberry-leaf extract；15 parts of Bitter Melon P.E；7 parts of squash polyoses；5 parts of apple grain；
5 parts of pawpaw grain；5 parts of pueraria lobata grain；Auxiliary material be (mixture of magnesium stearate and pregelatinized starch, magnesium stearate and pregelatinized starch
The weight ratio of mixture is 10 parts of 1:1).
Above-mentioned weight item is mixed according to the proportion, finished product can be obtained after granulation, whole grain, tabletting and packaging.
Wherein, the extracting method of mulberry-leaf extract are as follows: by dried mulberry leaf powder essence, 50% ethyl alcohol of 3 times of volumes, room temperature leaching is added
Bubble 12h, which is placed in 60 DEG C of warm water, extracts 2h, and during which every 30min clock concussion mixes primary, is then turned with 4200r/min
Speed centrifugation 30min, retains supernatant, finally supernatant is placed under the conditions of 60 DEG C and is condensed into dry powder, obtains after grinding to dry powder
Mulberry-leaf extract；
The extracting method of Bitter Melon P.E are as follows: fresh bitter is cleaned up, fritter is cut into, and remove seed, adds
The water of 1.5 times of volumes, is squeezed the juice with juice extractor, and obtained juicing is placed under the conditions of 0 DEG C by 200 mesh filter-cloth filterings and is stood
Supernatant is finally placed in and is condensed into dry powder under the conditions of 60 DEG C and obtains Bitter Melon P.E by 12h, then Aspirate supernatant.
The extracting method of squash polyoses are as follows: pumpkin is cut into small pieces, is added water to submerge, is squeezed the juice with juice extractor, the squeezing that will be obtained
Juice keeps the temperature 30min under the conditions of 70 DEG C, is then filtered and retains filtrate, be concentrated in vacuo under the conditions of 80 DEG C to filtrate
95% alcohol of 5 times of volumes is added afterwards, is stood overnight in 4 DEG C of refrigerators after uniform stirring, finally centrifugation removal supernatant remains
Under sediment be squash polyoses.
The production method of apple grain, pawpaw grain and pueraria lobata grain are as follows: fresh intact apple, pawpaw and pueraria lobata are chosen respectively,
After cleaning up they are cut into bulk respectively, are subsequently placed in 50 DEG C of environment and are dried, (water after drying process
Point content is 20% or so) they are put into crushing and pelletizing machine respectively 2 × 2mm~5 × 5mm size particle is made.
The extraction process of Abelmoschus Esculentus Linn extract the following steps are included:
S1, pulverization process is carried out to it after screening the impurity such as the intact dry okra of 100kg, removal dry leaves therein,
Then 70% ethyl alcohol is added to extract, the ratio between the volume of added 70% ethyl alcohol and dry gumbo weight is 20:1
(weight kg: volume L)；Extracting mode uses heating extraction, and Extracting temperature is 75 DEG C；Extraction time is 2h；
After S2, extraction, extracting solution is obtained through being separated by solid-liquid separation, using 80 mesh filter screen filtration extracting solutions, using tripodia
Formula centrifuge continues to dry residue, combined extract；
S3, said extracted liquid is concentrated, condensing mode is vacuum-concentrcted, wherein the control of vacuum-concentrcted temperature
Then system is dried concentrate using vacuum drying mode at 70 DEG C, be 55 DEG C by heating and temperature control, obtain Huang
Gumbo extract, extract weight 4.13kg.
Embodiment 6:
A kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food, the ingredient including following parts by weight:
70 parts of Abelmoschus Esculentus Linn extract；15 parts of mulberry-leaf extract；15 parts of Bitter Melon P.E；7 parts of squash polyoses；5 parts of apple grain；
5 parts of pawpaw grain；5 parts of pueraria lobata grain；Auxiliary material be (mixture of magnesium stearate and pregelatinized starch, magnesium stearate and pregelatinized starch
The weight ratio of mixture is 10 parts of 1:1).
Above-mentioned weight item is mixed according to the proportion, finished product can be obtained after granulation, whole grain, tabletting and packaging.
Wherein, the extracting method of mulberry-leaf extract are as follows: by dried mulberry leaf powder essence, 50% ethyl alcohol of 3 times of volumes, room temperature leaching is added
Bubble 12h, which is placed in 60 DEG C of warm water, extracts 2h, and during which every 30min clock concussion mixes primary, is then turned with 4200r/min
Speed centrifugation 30min, retains supernatant, finally supernatant is placed under the conditions of 60 DEG C and is condensed into dry powder, obtains after grinding to dry powder
Mulberry-leaf extract；
The extracting method of Bitter Melon P.E are as follows: fresh bitter is cleaned up, fritter is cut into, and remove seed, adds
The water of 1.5 times of volumes, is squeezed the juice with juice extractor, and obtained juicing is placed under the conditions of 0 DEG C by 200 mesh filter-cloth filterings and is stood
Supernatant is finally placed in and is condensed into dry powder under the conditions of 60 DEG C and obtains Bitter Melon P.E by 12h, then Aspirate supernatant.
The extracting method of squash polyoses are as follows: pumpkin is cut into small pieces, is added water to submerge, is squeezed the juice with juice extractor, the squeezing that will be obtained
Juice keeps the temperature 30min under the conditions of 70 DEG C, is then filtered and retains filtrate, be concentrated in vacuo under the conditions of 80 DEG C to filtrate
95% alcohol of 5 times of volumes is added afterwards, is stood overnight in 4 DEG C of refrigerators after uniform stirring, finally centrifugation removal supernatant remains
Under sediment be squash polyoses.
The production method of apple grain, pawpaw grain and pueraria lobata grain are as follows: fresh intact apple, pawpaw and pueraria lobata are chosen respectively,
After cleaning up they are cut into bulk respectively, are subsequently placed in 50 DEG C of environment and are dried, (water after drying process
Point content is 20% or so) they are put into crushing and pelletizing machine respectively 2 × 2mm~5 × 5mm size particle is made.
The extraction process of Abelmoschus Esculentus Linn extract the following steps are included:
S1, pulverization process is carried out to it after screening the impurity such as the intact dry okra of 100kg, removal dry leaves therein,
Then 80% pure methanol is added to extract, the ratio between the volume and dry gumbo weight of added 80% pure methanol is
18:1 (weight kg: volume L)；Extracting mode uses heating extraction, and Extracting temperature is 85 DEG C, extraction time 2h；
After S2, extraction, extracting solution is obtained through being separated by solid-liquid separation, using 80 mesh filter screen filtration extracting solutions, using tripodia
Formula centrifuge continues to dry residue, combined extract；
S3, said extracted liquid is concentrated, condensing mode is vacuum-concentrcted, wherein the control of vacuum-concentrcted temperature
Then system is dried concentrate using vacuum drying mode at 80 DEG C, be 60 DEG C by heating and temperature control, obtain Huang
Gumbo extract, extract weight 3.98kg.
Embodiment 7:
A kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food, the ingredient including following parts by weight:
90 parts of Abelmoschus Esculentus Linn extract；20 parts of mulberry-leaf extract；20 parts of Bitter Melon P.E；10 parts of squash polyoses；Apple grain 7
Part；7 parts of pawpaw grain；7 parts of pueraria lobata grain；Auxiliary material (mixture of microcrystalline cellulose, magnesium stearate and pregelatinized starch, microcrystalline cellulose
The weight ratio of the mixture of element, magnesium stearate and pregelatinized starch is 20 parts of 1:1:1).
Above-mentioned weight item is mixed according to the proportion, finished product can be obtained after granulation, whole grain, tabletting and packaging.
Wherein, the extracting method of mulberry-leaf extract are as follows: by dried mulberry leaf powder essence, 50% ethyl alcohol of 3 times of volumes, room temperature leaching is added
Bubble 12h, which is placed in 60 DEG C of warm water, extracts 2h, and during which every 30min clock concussion mixes primary, is then turned with 4200r/min
Speed centrifugation 30min, retains supernatant, finally supernatant is placed under the conditions of 60 DEG C and is condensed into dry powder, obtains after grinding to dry powder
Mulberry-leaf extract；
The extracting method of Bitter Melon P.E are as follows: fresh bitter is cleaned up, fritter is cut into, and remove seed, adds
The water of 1.5 times of volumes, is squeezed the juice with juice extractor, and obtained juicing is placed under the conditions of 0 DEG C by 200 mesh filter-cloth filterings and is stood
Supernatant is finally placed in and is condensed into dry powder under the conditions of 60 DEG C and obtains Bitter Melon P.E by 12h, then Aspirate supernatant.
The extracting method of squash polyoses are as follows: pumpkin is cut into small pieces, is added water to submerge, is squeezed the juice with juice extractor, the squeezing that will be obtained
Juice keeps the temperature 30min under the conditions of 70 DEG C, is then filtered and retains filtrate, be concentrated in vacuo under the conditions of 80 DEG C to filtrate
95% alcohol of 5 times of volumes is added afterwards, is stood overnight in 4 DEG C of refrigerators after uniform stirring, finally centrifugation removal supernatant remains
Under sediment be squash polyoses.
The production method of apple grain, pawpaw grain and pueraria lobata grain are as follows: fresh intact apple, pawpaw and pueraria lobata are chosen respectively,
After cleaning up they are cut into bulk respectively, are subsequently placed in 50 DEG C of environment and are dried, (water after drying process
Point content is 20% or so) they are put into crushing and pelletizing machine respectively 2 × 2mm~5 × 5mm size particle is made.
The extraction process of Abelmoschus Esculentus Linn extract the following steps are included:
S1, slicing treatment is carried out to it after screening the impurity such as the intact cadmium yellow gumbo of 100kg, removal leaf therein, so
After 30% methanol be added extract, the ratio between the volume of added 30% methanol and fresh gumbo weight is 30:1 (weight
Amount kg: volume L)；Extracting mode uses Microwave Extraction, and the power of extraction is 200W/L, extraction time 3h；
After S2, extraction, extracting solution is obtained through being separated by solid-liquid separation, using 80 mesh filter screen filtration extracting solutions, using tripodia
Formula centrifuge continues to dry residue, combined extract；
S3, said extracted liquid is concentrated, condensing mode is vacuum-concentrcted, wherein the control of vacuum-concentrcted temperature
Then system is dried concentrate in such a way that ultrasonic wave is dry at 60 DEG C, dry power is 10W/cm2, dry
Temperature is 20 DEG C, obtains Abelmoschus Esculentus Linn extract, extract weight 3.7kg.
Embodiment 8:
A kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food, the ingredient including following parts by weight:
90 parts of Abelmoschus Esculentus Linn extract；20 parts of mulberry-leaf extract；20 parts of Bitter Melon P.E；10 parts of squash polyoses；Apple grain 7
Part；7 parts of pawpaw grain；7 parts of pueraria lobata grain；Auxiliary material (mixture of microcrystalline cellulose, magnesium stearate and pregelatinized starch, microcrystalline cellulose
The weight ratio of the mixture of element, magnesium stearate and pregelatinized starch is 20 parts of 1:1:1).
Above-mentioned weight item is mixed according to the proportion, finished product can be obtained after granulation, whole grain, tabletting and packaging.
Wherein, the extracting method of mulberry-leaf extract are as follows: by dried mulberry leaf powder essence, 50% ethyl alcohol of 3 times of volumes, room temperature leaching is added
Bubble 12h, which is placed in 60 DEG C of warm water, extracts 2h, and during which every 30min clock concussion mixes primary, is then turned with 4200r/min
Speed centrifugation 30min, retains supernatant, finally supernatant is placed under the conditions of 60 DEG C and is condensed into dry powder, obtains after grinding to dry powder
Mulberry-leaf extract；
The extracting method of Bitter Melon P.E are as follows: fresh bitter is cleaned up, fritter is cut into, and remove seed, adds
The water of 1.5 times of volumes, is squeezed the juice with juice extractor, and obtained juicing is placed under the conditions of 0 DEG C by 200 mesh filter-cloth filterings and is stood
Supernatant is finally placed in and is condensed into dry powder under the conditions of 60 DEG C and obtains Bitter Melon P.E by 12h, then Aspirate supernatant.
The extracting method of squash polyoses are as follows: pumpkin is cut into small pieces, is added water to submerge, is squeezed the juice with juice extractor, the squeezing that will be obtained
Juice keeps the temperature 30min under the conditions of 70 DEG C, is then filtered and retains filtrate, be concentrated in vacuo under the conditions of 80 DEG C to filtrate
95% alcohol of 5 times of volumes is added afterwards, is stood overnight in 4 DEG C of refrigerators after uniform stirring, finally centrifugation removal supernatant remains
Under sediment be squash polyoses.
The production method of apple grain, pawpaw grain and pueraria lobata grain are as follows: fresh intact apple, pawpaw and pueraria lobata are chosen respectively,
After cleaning up they are cut into bulk respectively, are subsequently placed in 50 DEG C of environment and are dried, (water after drying process
Point content is 20% or so) they are put into crushing and pelletizing machine respectively 2 × 2mm~5 × 5mm size particle is made.
The extraction process of Abelmoschus Esculentus Linn extract the following steps are included:
S1, slicing treatment is carried out to it after screening the impurity such as the intact cadmium yellow gumbo of 100kg, removal leaf therein, so
After 100% methanol (not aqueous) be added extract, the ratio between the volume of added 100% methanol and fresh gumbo weight
For 10:1 (weight kg: volume L)；Extracting mode uses Microwave Extraction, and the power of extraction is 350W/L, extraction time 3.5h；
After S2, extraction, extracting solution is obtained through being separated by solid-liquid separation, using 80 mesh filter screen filtration extracting solutions, using tripodia
Formula centrifuge continues to dry residue, combined extract；
S3, said extracted liquid is concentrated, condensing mode is vacuum-concentrcted, wherein the control of vacuum-concentrcted temperature
Then system is dried concentrate in such a way that ultrasonic wave is dry at 70 DEG C, dry power is 70W/cm2, dry
Temperature is 25 DEG C, obtains Abelmoschus Esculentus Linn extract, extract weight 3.87kg.
Embodiment 9:
A kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food, the ingredient including following parts by weight:
90 parts of Abelmoschus Esculentus Linn extract；20 parts of mulberry-leaf extract；20 parts of Bitter Melon P.E；10 parts of squash polyoses；Apple grain 7
Part；7 parts of pawpaw grain；7 parts of pueraria lobata grain；Auxiliary material (mixture of microcrystalline cellulose, magnesium stearate and pregelatinized starch, microcrystalline cellulose
The weight ratio of the mixture of element, magnesium stearate and pregelatinized starch is 20 parts of 1:1:1).
Above-mentioned weight item is mixed according to the proportion, finished product can be obtained after granulation, whole grain, tabletting and packaging.
Wherein, the extracting method of mulberry-leaf extract are as follows: by dried mulberry leaf powder essence, 50% ethyl alcohol of 3 times of volumes, room temperature leaching is added
Bubble 12h, which is placed in 60 DEG C of warm water, extracts 2h, and during which every 30min clock concussion mixes primary, is then turned with 4200r/min
Speed centrifugation 30min, retains supernatant, finally supernatant is placed under the conditions of 60 DEG C and is condensed into dry powder, obtains after grinding to dry powder
Mulberry-leaf extract；
The extracting method of Bitter Melon P.E are as follows: fresh bitter is cleaned up, fritter is cut into, and remove seed, adds
The water of 1.5 times of volumes, is squeezed the juice with juice extractor, and obtained juicing is placed under the conditions of 0 DEG C by 200 mesh filter-cloth filterings and is stood
Supernatant is finally placed in and is condensed into dry powder under the conditions of 60 DEG C and obtains Bitter Melon P.E by 12h, then Aspirate supernatant.
The extracting method of squash polyoses are as follows: pumpkin is cut into small pieces, is added water to submerge, is squeezed the juice with juice extractor, the squeezing that will be obtained
Juice keeps the temperature 30min under the conditions of 70 DEG C, is then filtered and retains filtrate, be concentrated in vacuo under the conditions of 80 DEG C to filtrate
95% alcohol of 5 times of volumes is added afterwards, is stood overnight in 4 DEG C of refrigerators after uniform stirring, finally centrifugation removal supernatant remains
Under sediment be squash polyoses.
The production method of apple grain, pawpaw grain and pueraria lobata grain are as follows: fresh intact apple, pawpaw and pueraria lobata are chosen respectively,
After cleaning up they are cut into bulk respectively, are subsequently placed in 50 DEG C of environment and are dried, (water after drying process
Point content is 20% or so) they are put into crushing and pelletizing machine respectively 2 × 2mm~5 × 5mm size particle is made.
The extraction process of Abelmoschus Esculentus Linn extract the following steps are included:
S1, slicing treatment is carried out to it after screening the impurity such as the intact cadmium yellow gumbo of 100kg, removal leaf therein, so
After 100% ethyl alcohol (not aqueous) be added extract, the ratio between the volume of added 100% ethyl alcohol and fresh gumbo weight
For 10:1 (weight kg: volume L)；Extracting mode uses Microwave Extraction, and the power of extraction is 500W/L, extraction time 4h；
After S2, extraction, extracting solution is obtained through being separated by solid-liquid separation, using 80 mesh filter screen filtration extracting solutions, using tripodia
Formula centrifuge continues to dry residue, combined extract；
S3, said extracted liquid is concentrated, condensing mode is vacuum-concentrcted, wherein the control of vacuum-concentrcted temperature
Then system is dried concentrate in such a way that ultrasonic wave is dry at 80 DEG C, dry power is 100W/cm2, dry
Temperature be 30 DEG C, obtain Abelmoschus Esculentus Linn extract, extract weight 3.72kg.
Experimental design:
For the effect of lowering blood sugar for verifying Abelmoschus Esculentus Linn extract hypoglycemia healthcare food of the invention, this experiment uses hyperglycemia
Animal model tests it, since embodiment 1-3 is same formula, embodiment 4-6 is same formula, embodiment 7-
9 be same formula, and therefore, health care obtained by these three formulas of embodiment 1, embodiment 4 and embodiment 7 is only verified in this experiment
The effect of lowering blood sugar of food.
(1) animal model:
The animal model of this experiment is mouse, and totally 65, male, weight is between 14-16g, and Quality of Experimental Animals closes
Lattice card number is No.11400700229061.These mouse are raised in the IVC cage box of barrier, and 5, every cage, cage box is put
The condition for the animal house set is that 12 hours light and shade alternatings, temperature is 22-26 DEG C, humidity 40-60%.Mouse in breeding process
Free water is ingested.Experimental animal Ethic review guidelines are deferred in experimental animal operation and processing.
(2) experimental group:
Experimental animal is randomly divided into 5 groups according to weight, and every group 13, every group is numbered each mouse from 1-13.Its
In, first group is Normal group, second and third, four groups be respectively processing group 1, processing group 2, processing group 3, the 5th group is high in fat
High sugar control group；Normal group is normally to feed before experiment, processing group 1, processing group 2, processing group 3 and high sugar control high in fat
Group experiment carries out persistently high sugar high in fat for the previous period and intervenes.
(3) processing scheme:
The processing scheme of each experimental group of table 1
(4) Composition analyzed:
Processing plucks eyeball after 30 days and takes anticoagulation 500ul, according to glycosylated hemoglobin (HbA1c) assay kit (enzyme process)
The step of Norudia N HbA1c specification, detects the content of hemoglobin of mouse in each experimental group, and testing result is as follows:
Glycosylated hemoglobin percentage in 2 processing group 1 of table, processing group 2 and processing group 3 measures table
The glycosylated hemoglobin percentage of 3 Normal group of table and high sugared control group high in fat measures table
Glycosylated hemoglobin is product of the hemoglobin in conjunction with carbohydrate in red blood cell, and the combination of blood glucose and hemoglobin is raw
It is irreversible reaction at glycosylated hemoglobin, and directly proportional to blood sugar concentration, and is kept for 120 days or so, and HbAle egg
It is white much than glucostasis, be reflection so glycosylated hemoglobin can reflect the blood glucose average level in longer period of time
The good index of glycemic control quality.
By experimental result it can be found that passing through the Huang in embodiment 1, embodiment 4 and embodiment 7 to high sugared mouse high in fat
After the processing of gumbo extract health product after 30 days, the high sugared intracorporal glycated hemoglobin levels of mouse high in fat are below high sugar high in fat
Control group maintains an equal level with Normal group, illustrates that Abelmoschus Esculentus Linn extract hypoglycemia healthcare food can delay the blood glucose of experimental animal
It increases, there is apparent effect of lowering blood sugar.
Above the embodiments of the present invention are described in detail, but the present invention is not limited to described embodiments.It is right
For those skilled in the art, in the case where not departing from the principle of the invention and spirit, these embodiments are carried out more
Kind change, modification, replacement and modification, still fall in protection scope of the present invention.
Claims (10)
1. a kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food, it is characterised in that: the ingredient including following parts by weight:
50~80 parts of Abelmoschus Esculentus Linn extract；10~20 parts of mulberry-leaf extract；10~20 parts of Bitter Melon P.E；Squash polyoses 5-10
Part；3-7 parts of apple grain；3-7 parts of pawpaw grain；3-7 parts of pueraria lobata grain；5~20 parts of auxiliary material.
2. a kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food as described in claim 1, it is characterised in that: including following weight
The ingredient of part:
70 parts of Abelmoschus Esculentus Linn extract；15 parts of mulberry-leaf extract；15 parts of Bitter Melon P.E；7 parts of squash polyoses；5 parts of apple grain；Pawpaw
5 parts of grain；5 parts of pueraria lobata grain；10 parts of auxiliary material.
3. a kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food as described in claim 1, it is characterised in that: the mulberry leaf extract
The extracting method of object are as follows: by dried mulberry leaf powder essence, 50% ethyl alcohol of 3 times of volumes is added, soaking at room temperature 12h is placed on 60 DEG C of warm water
Middle extracting 2h, during which every 30min clock concussion mixes primary, is then centrifuged 30min with the revolving speed of 4200r/min, retains supernatant, most
Supernatant is placed under the conditions of 60 DEG C afterwards and is condensed into dry powder, mulberry-leaf extract is obtained after grinding to dry powder；
The extracting method of the Bitter Melon P.E are as follows: fresh bitter is cleaned up, fritter is cut into, and remove seed, adds
The water of 1.5 times of volumes, is squeezed the juice with juice extractor, and obtained juicing is placed under the conditions of 0 DEG C by 200 mesh filter-cloth filterings and is stood
Supernatant is finally placed in and is condensed into dry powder under the conditions of 60 DEG C and obtains Bitter Melon P.E by 12h, then Aspirate supernatant.
4. a kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food as described in claim 1, it is characterised in that: the squash polyoses
Extracting method are as follows: pumpkin is cut into small pieces, is added water to submerge, is squeezed the juice with juice extractor, obtained juicing is protected under the conditions of 70 DEG C
Then warm 30min is filtered and retains filtrate, 5 times of volumes are added after being concentrated in vacuo under the conditions of 80 DEG C to filtrate
95% alcohol is stood overnight in 4 DEG C of refrigerators after uniform stirring, and finally centrifugation removal supernatant, remaining sediment is south
Melon polysaccharide.
5. a kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food as described in claim 1, it is characterised in that: the okra mentions
Object is taken to extract using fresh gumbo or dry gumbo, the auxiliary material is microcrystalline cellulose, magnesium stearate, sodium alginate and pregelatinated
At least one of starch.
6. a kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food as described in claim 1, it is characterised in that: the okra mentions
Take the extraction process of object the following steps are included:
S1, it is extracted after being screened, cleaned, crushed or being sliced to okra added with solvent, wherein crushing is for dry
Mode used by okra, slice are modes used by being directed to cadmium yellow gumbo,
After S2, extraction, obtain extracting solution through being separated by solid-liquid separation, using 80 mesh filter screen filtration extracting solutions, using 3-foot from
Scheming continues to dry residue, combined extract；
S3, extracting solution obtained in S2 step is concentrated, obtains Abelmoschus Esculentus Linn extract after dry.
7. a kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food as claimed in claim 6, it is characterised in that: the organic solvent
For pure organic solvent or mixed organic solvents, the pure organic solvent is one of 100% methanol and 100% ethyl alcohol, described
Mixed organic solvents are that pure organic solvent is mixed with water, the composition ratio of the mixed organic solvents are as follows: pure organic solvent:
Water=0.3~1:1；The weight of the volume and cadmium yellow gumbo of the organic solvent is 10:1~30:1, the organic solvent
Volume and the weight of dry okra are 15:1~25:1.
8. a kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food as claimed in claim 6, it is characterised in that: in the S1 step
Extracting mode be heating extraction, ultrasonic wave extraction and Microwave Extraction in any one, the Extracting temperature of the heating extraction
It is 70~85 DEG C, 2~3h of extraction time；The power of the ultrasonic wave extraction is 150~180W/L, and extraction time is 2~2.5h；
The power of the Microwave Extraction is 200~500W/L, and extraction time is 3~4h.
9. a kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food as claimed in claim 6, it is characterised in that: in the S3 step
Condensing mode be vacuum-concentrcted, the temperature of the vacuum-concentrcted is 60~80 DEG C.
10. a kind of Abelmoschus Esculentus Linn extract hypoglycemia healthcare food as claimed in claim 4, it is characterised in that: the S3 step
In drying mode be that vacuum drying, blast heating be dry and ultrasonic wave it is dry in any one, it is described vacuum drying plus
Hot temperature is 50~60 DEG C；The dry heating temperature of the blast heating is 40~50 DEG C；The dry power of the ultrasonic wave is
10~100W/cm2, drying temperature is 20~30 DEG C.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109601684A (en) * | 2019-01-22 | 2019-04-12 | 广州市顺芝堂生物科技有限公司 | A kind of gumbo mulberry leaf pressed candy and preparation method thereof |
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| CN109601684A (en) * | 2019-01-22 | 2019-04-12 | 广州市顺芝堂生物科技有限公司 | A kind of gumbo mulberry leaf pressed candy and preparation method thereof |
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