CN109045102A - A kind of drug and preparation method thereof for preventing and treating swine flu - Google Patents
A kind of drug and preparation method thereof for preventing and treating swine flu Download PDFInfo
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Abstract
The invention discloses a kind of drugs for preventing and treating swine flu, are made of the bulk pharmaceutical chemicals of following proportion by weight: 100 parts of rhizome of cyrtomium, 230-265 parts of radix bupleuri, 180-220 parts of radix saposhnikoviae, 280-320 parts of Radix Astragali, 180-215 parts of Rhizoma Atractylodis Macrocephalae, 180-200 parts of lance asiabell root, 180-215 parts of Radix Isatidis, 240-270 parts of the achene of Siberian cocklebur, 180-215 parts of the stem pith of the rice-paper plant.The drug can effectively prevent swine flu disease；Pig immunity can be improved using drug of the invention in advance especially for the pig of no infection swine flu disease, have good prevention effect to swine flu；There is good therapeutic effect for the pig of affected pig influenza disease symptoms.
Description
Technical field
The present invention relates to the drug of boar epidemic disease prevention and treatment, especially a kind of pair of swine flu has obvious prevent and treat to make
Drug and preparation method thereof.
Background technique
Swine influenza is a kind of acute, infectiousness respiratory illness of pig.It is characterized in that burst, coughs, breathing
Difficulty is generated heat and is lapsed to rapidly.Swine flu is in pig body because of respiratory disease caused by virus.Swine flu is by Flu-A disease
Malicious (influenza A) causes, and usually between pig, infectiousness is very high but will not usually cause death for outburst.Autumn and winter belongs to high
The hair phase, but whole year can propagate.Swine flu is recognized as influenza virus C (c-type influenza virus) or Flu-A disease more
One of the subspecies of poison.The virus can cause Influenza Outbreak in swinery.The mankind seldom infect swine influenza virus under normal conditions.It should
The disease incidence of disease is high, and incubation period is 2-7 days, the course of disease 1 week or so.Sick pig early stage generates heat suddenly, lassitude, appetite stimulator
Or abolish, normal accumbency together, are reluctant activity, expiratory dyspnea, fierceness cough, eye nose flows out mucus.If in period of disease treatment
Not in time, then easily concurrent bronchitis, pneumonia and pleurisy etc., increase the case fatality rate of pig.
In the prevention and treatment of clinical practice swine flu, it is widely used since antibiotic has the characteristics that control complication,
Cooperate the drugs such as a large amount of antipyretic-antalgic, glucocorticoids simultaneously.However also deepen while inhibiting body inflammatory reaction
Immunosupress, causes the state of an illness more to deteriorate.Chinese herbal medicine is as natural products, and abundant with medicine source, residual hazard is lower or without residual
Poison, Small side effects, the advantages that being not likely to produce drug resistance；It is adjustable body's immunity simultaneously, suppressing virus replication improves clinical
Symptom is widely used on treatment disease of viral infection.Therefore, using herbal control swine flu, prospect is extremely wide.
Summary of the invention
A kind of drug for preventing and treating swine flu is provided the purpose of the present invention is overcoming the above-mentioned insufficient of the prior art, the present invention
Drug can effectively prevent swine flu disease；Use drug of the invention can in advance especially for the pig of no infection swine flu disease
Pig immunity is improved, the pig for suffering from influenza disease symptoms has good therapeutic effect.
It is a further object of the present invention to provide a kind of preparation method of said medicine, simple process, bulk pharmaceutical chemicals are common,
Cheaply.
The technical scheme is that a kind of drug for preventing and treating swine flu, is by the bulk pharmaceutical chemicals of following proportion by weight
It is made: 100 parts of rhizome of cyrtomium, 230-265 parts of radix bupleuri, 180-220 parts of radix saposhnikoviae, 280-320 parts of Radix Astragali, 180-215 parts of Rhizoma Atractylodis Macrocephalae, lance asiabell root
180-200 parts, 180-215 parts of Radix Isatidis, 240-270 parts of the achene of Siberian cocklebur, 180-215 parts of the stem pith of the rice-paper plant.
Its further preferred mass part proportion are as follows: 100 parts of rhizome of cyrtomium, 230-260 parts of radix bupleuri, radix saposhnikoviae 190-220 parts, Radix Astragali
290-320 parts, 180-205 parts of Rhizoma Atractylodis Macrocephalae, 190-200 parts of lance asiabell root, 190-215 parts of Radix Isatidis, 240-260 parts of the achene of Siberian cocklebur, the stem pith of the rice-paper plant
180-205 parts.
Its further preferred mass part proportion are as follows: 100 parts of rhizome of cyrtomium, 240-260 parts of radix bupleuri, radix saposhnikoviae 190-210 parts, Radix Astragali
290-310 parts, 190-205 parts of Rhizoma Atractylodis Macrocephalae, 195-200 parts of lance asiabell root, 190-210 parts of Radix Isatidis, 245-260 parts of the achene of Siberian cocklebur, the stem pith of the rice-paper plant
185-205 parts.
Its further preferred mass part proportion are as follows: 100 parts of rhizome of cyrtomium, 250-260 parts of radix bupleuri, radix saposhnikoviae 200-210 parts, Radix Astragali
290-300 parts, 190-200 parts of Rhizoma Atractylodis Macrocephalae, 195-200 parts of lance asiabell root, 200-210 parts of Radix Isatidis, 250-260 parts of the achene of Siberian cocklebur, the stem pith of the rice-paper plant
190-205 parts.
Its further preferred mass part proportion are as follows: 100 parts of rhizome of cyrtomium, 250 parts of radix bupleuri, 200 parts of radix saposhnikoviae, 300 parts of Radix Astragali, white
200 parts of art, 200 parts of lance asiabell root, 200 parts of Radix Isatidis, 250 parts of the achene of Siberian cocklebur, 200 parts of the stem pith of the rice-paper plant.
It is of the invention another solution is that a kind of preparation method for the drug for preventing and treating swine flu, mainly includes as follows
Step:
One, medicine material is weighed by proportion by weight；
Two, the raw material claimed is crushed, is uniformly mixed, obtain the drug of prevention and treatment swine flu.
It is of the invention another solution is that step 2 raw material crushes after, cross 100-300 mesh.
The primary raw material medicine that the present invention uses is described as follows:
Rhizome of cyrtomium: alias: Matteuccia strthiopteris, small rhizome of cyrtomium, fortune holly fern rhizome, small golden pheasant tail；Medicine name: Dryopteris bissetiaha (Bak) C. Chr-Nephrodium bisseianum Bak；Classification: Dryopteridaceae
(Dryopteridaceae), Dryopteris (Dryopteris)；Source: for the rhizome of Dryopteridaceae plant Dryopteris bissetiaha (Bak) C. Chr-Nephrodium bisseianum Bak；Function
Effect: clearing heat and detoxicating, cooling blood and hemostasis, desinsection；The major functions: for when heresy sense, partial heat person, fever weight, aversion to cold is light, have a headache, swallows red, pharynx
Swollen, dry and thirsty, red tongue body, thin white, the floating pulse person of tongue fur；Meridian distribution of property and flavor: it is pungent, it is bitter, it trembles with fear；" Xinhua's book on Chinese herbal medicine outline ": rhizome: there is heat-clearing
The effect of removing toxic substances；For preventing influenza.
Radix bupleuri: alias: Asia puecon recklessly, smoke Shennong's Herbal, mountain dish, eat careless " Wu Pu Bencao ", faggot " product converge essence want ", rue
Wormwood artemisia (Compendium of Materia Medica).Meridian distribution of property and flavor: cold nature, bitter, pungent, return liver warp, gallbladder channel, tool soothing liver-gallbladder, the function dredged gas relieve stagnation, dissipate fire
Effect.Function: saturating table expels the heat-evil, soothing liver-qi stagnation, lifting disease.The major functions: the fever that cures cold, fever and chills deficient fever；Children's acne rash waste heat,
Lean and haggard abdomen expands, malaria, stagnation of QI due to depression of the liver, sternal rib pain, rectal prolapse, and uterus falls off, irregular menstruation.
Radix saposhnikoviae: alias copper rue, returns grass, hundred at Hui Yun.Channel tropism: bladder meridian；Lung channel；The spleen channel；Liver Channel.Effect: wind-dispelling solution
It is table, expel endogenous wind to relieve convulsion, spasmolysis, antipruritic.The major functions: affection of exogenous wind-cold；Headache bodily pain；Rheumatic arthralgia；Skeletal pain；Abdominal pain diarrhoea；Intestines wind
Lower blood；Tetanus；Rubella itch；Sore from the beginning of.Nature and flavor: acrid flavour；It is sweet；Slightly warm in nature.Medicine elementary source: for umbelliferae Saposhnikovia divaricata
Root.Effect classification: diaphoretic medicine, dispel-wind drug.
Radix Astragali: also known as wearing crushed grain, wear mulberry, grass, hundred, the prince's descendants in Compendium of Material Medica, (" stilbene " original work are " over sixty years of age ")；Smell (root)
It is sweet, tepor, nontoxic；The major functions: urinary obstruction, wine subcutaneous ulcer Huang disease, gonorrhoea, sallow terribly thirsty, old people constipation, blood strangury, few leaching, haematemesis, cough
Purulence hemoptysis, pulmonary abscess, threatened abortion, polyhidrosis around the external genitals are wet to itch.There is tonifying middle-Jiao and Qi arrest sweating, control chronic nephritis, the albumen that disappears, solution taking poison and growing muscle due, help
Taste and other effects.Chinese medicine Radix Astragali is the root of leguminous herbaceous plant's astragalus mongolicus, Astragalus membranacus, and there is invigorating qi for strengthening superficies, Li Shui to move back
Swollen, pus draining and toxin expelling, myogenic and other effects；Radix Astragali is a variety of micro- containing saponin, sucrose, polysaccharide, a variety of amino acid, folic acid and selenium, zinc, copper etc.
Secondary element；There are enhancing body's immunity, liver protection, diuresis, anti-aging, resisting stress, decompression and wide antibacterial action.
Rhizoma Atractylodis Macrocephalae: alias small wooden raft Ji, Yu Shu, winter Rhizoma Atractylodis Macrocephalae, wash rice art, poplar small wooden raft, Wu Shu, piece art, rhizoma atractylodis etc. belong to composite family, [WTBX
Herbaceos perennial.Nice and cool weather is liked, is used as medicine with rhizome, there is multinomial medicinal function.It is distributed mainly on Sichuan, Yunnan, expensive
The mountain areas such as state wetland.Rhizoma Atractylodis Macrocephalae has strengthening the spleen and replenishing qi, the effect of eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention, is used for spleen eating less, abdominal distention diarrhea,
Phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, threatened abortion." medicine origin " is recorded: " the dry and middle QI invigorating of dehumidifying benefit, middle benefit gas are gone in taste
It is wet, remove stomach energy, strong taste, into diet, miscarriage prevention."
Lance asiabell root: for campanulaceae of the genus codonopsis sheep cream Codonopsislanceolata(Sieb.etZucc.) Trautv.'s
Root.With supplementing qi and nourishing yin, removing toxicity for detumescence, apocenosis, the effect of promoting lactation.Cure mainly spiritlessness and weakness, dizziness headache, pulmonary abscess, acute mastitis, intestines
Carbuncle, sore furuncle poison, tonsillitis, scrofula, postpartum cream is few, leukorrhea, venomous snake bite.
Radix Isatidis: alias: indigo-blue, indigo root, manyflower glorybower root are a kind of Chinese medicines.For the dry of cruciferae isatis
It dry, is usually excavated, can be used as medicine after processing in the fall.Its is cold in nature, bitter after taste is first slightly sweet, has clearing heat and detoxicating, prevention
The effect of flu, relieving sore-throat.It is mainly used for treating the diseases such as the dark reddish purple dark, scarlet fever of febrile virulent maculae, tongue.
The achene of Siberian cocklebur: alias: lice head of the horse, the achene of Siberian cocklebur, stout pale, the road number of people, eight naked, grey prodigals of thorn, continuous grey prodigal, Qiang's are naked
Son, green spine rob son, silly head mother-in-law, Hu Cangzi, wild eggplant, pig ear, dish ear, grey son, and Cantonese is called magnetic head awns (head awns of being crazy about).
Belong to the fruit with involucre of composite family, Xanthium annual herb compositae plant Siberian cocklebur, the achene of Siberian cocklebur belongs to common Chinese herbal medicine, has and dissipates
Wind dehumidifies sensible and other effects.
The stem pith of the rice-paper plant: alias bandit takes off, from southern, Huo Tuo, partial quotient, flowers and plants etc., is the stem marrow of Araliaceae rice-paper plant；Return lung, stomach
Through clear snobbish water；It promotes lactation, is used for the puckery pain of stranguria；Difficult urination；Oedema；Jaundice；Damp-warm diseases；Scanty drak urine；Postpartum cream is few；Through
It closes；Leukorrhagia.
Drug of the invention can effectively prevent swine flu disease；It is used in advance especially for the pig of no infection swine flu disease
Pig immunity can be improved in drug of the invention, has good prevention effect to swine flu；Have for the pig of affected pig influenza disease symptoms
Good therapeutic effect.
When drug application method of the invention is fed every time, every 500 kg diet weighs 1000-1500 grams of prevention and treatment pig stream
The drug of sense, then by the drug with suitable water to mixing up, then be added feed in, mix, feed immediately, daily sooner or later respectively feed
It supports once, each every 2-3 kilograms of pig feed added with drug, 10 days as a treatment course can feed this drug one every 7 days
A course for the treatment of.
In order to illustrate more clearly of the present invention, following embodiment is enumerated, but it is without any restrictions to the range of invention.
Specific embodiment
Embodiment 1
Weigh rhizome of cyrtomium 100g, radix bupleuri 250g, windproof 200g, Radix Astragali 300g, Rhizoma Atractylodis Macrocephalae 200g, lance asiabell root 200g, Radix Isatidis 200g is grey
Ears or side handles of a utensil 250g, stem pith of the rice-paper plant 200g, these material compositions are the quality after drying, and are ground into 150-300 with micronizer
Mesh is uniformly mixed, is then packed with plastic bag sealing, and the drug of prevention and treatment swine flu is made.
Application method: when drug application method of the invention is fed every time, every 500 kg diet weighs 1000 grams of prevention and treatments
The drug of swine flu, then by the drug with suitable water to mixing up, then be added feed in, mix, feed immediately, daily sooner or later
It is each to feed once, it is freely eaten, 7 days as a course for the treatment of, and one course for the treatment of of this drug can be fed every 10 days.
Embodiment 2-12, comparative example 1-2
Embodiment 2-12 is other than raw material mass mixture ratio is different from embodiment 1, raw material type and step of preparation process and use
Method is same as Example 1, and comparative example 1 is that lance asiabell root is eliminated on the basis of embodiment 12, and comparative example 2 is in embodiment 12
On the basis of eliminate the stem pith of the rice-paper plant, raw material used in embodiment 1-12, comparative example 1-2 and quality are as shown in Table 1 below.
Table 1
。
Clinical test one:
Carry out the clinical test of prevention and treatment piglet flu pharmaceutical in Hunan cultivation base, the prevention and treatment piglet obtained using embodiment 1
The drug of influenza suffers from influenza piglet by clinical treatment 150, and the every 500 kilograms of feeds mixed up of test group weigh 1000 grams and prevent
Swine flu drug is controlled, it is sooner or later each daily to feed once, allow pig to be freely eaten, control group are as follows: qingkailing injections+hydrochloric acid woods can be mould
Plain injection+potent Amoxicillin, mixed volume ratio 1:1:1 mix intramuscular injection, daily by 0.4 milliliter of every kg body weight
It 2 times, is used in conjunction 7 days.After 7 days, test result is shown, test group compared with the control group, therapeutic effect significant difference, cure rate with
Total effective rate is higher by 15% or more than control group.For test group pig after curing, development condition is good, no rebound phenomenon；And it compares
After group pig is cured, still there are 13 pigs to occur repeatedly.
Clinical test two:
On the pig farm that epidemic situation occurs, 300 non-morbid pigs of health are randomly divided into 15 groups, every group 20, wherein 12 groups are drug
Prevention group, 2 groups are comparative example group, the feed that drug described in feeding embodiment 1-12, comparative example 1-2 is made into respectively, every 500 kilograms
The feed mixed up, weighs 1100 grams of prevention and treatment swine flu drugs, and another group is control group, and feeding is not added the identical feed of drug, and 15
The group other measures of pig all normally sterilize immune programme by pig farm, and 7 days as a course for the treatment of, feed this drug one treatment again every 10 days
Journey the results are shown in Table 2.
Table 2
。
The result shows that: the disease incidence of chemoprophylaxis group piglet influenza is more much lower than comparative example and control group, and medicine group is sent out
Spirit, the appetite of sick pig are all better than comparative example and control group, and illness symptom is also light compared with comparative example and control group.
Claims (7)
1. a kind of drug for preventing and treating swine flu, it is characterized in that: it is made of the bulk pharmaceutical chemicals of following proportion by weight: rhizome of cyrtomium 100
Part, 230-265 parts of radix bupleuri, 180-220 parts of radix saposhnikoviae, 280-320 parts of Radix Astragali, 180-215 parts of Rhizoma Atractylodis Macrocephalae, 180-200 parts of lance asiabell root, plate
Blue root 180-215 parts, 240-270 parts of the achene of Siberian cocklebur, 180-215 parts of the stem pith of the rice-paper plant.
2. the drug of swine flu is prevented and treated according to claim 1, it is characterized in that: 100 parts of rhizome of cyrtomium, 230-260 parts of radix bupleuri, radix saposhnikoviae
190-220 parts, 290-320 parts of Radix Astragali, 180-205 parts of Rhizoma Atractylodis Macrocephalae, 190-200 parts of lance asiabell root, 190-215 parts of Radix Isatidis, the achene of Siberian cocklebur
240-260 parts, 180-205 parts of the stem pith of the rice-paper plant.
3. the drug of swine flu is prevented and treated according to claim 1, it is characterized in that: 100 parts of rhizome of cyrtomium, 240-260 parts of radix bupleuri, radix saposhnikoviae
190-210 parts, 290-310 parts of Radix Astragali, 190-205 parts of Rhizoma Atractylodis Macrocephalae, 195-200 parts of lance asiabell root, 190-210 parts of Radix Isatidis, the achene of Siberian cocklebur
245-260 parts, 185-205 parts of the stem pith of the rice-paper plant.
4. the drug of swine flu is prevented and treated according to claim 1, it is characterized in that: 100 parts of rhizome of cyrtomium, 250-260 parts of radix bupleuri, radix saposhnikoviae
200-210 parts, 290-300 parts of Radix Astragali, 190-200 parts of Rhizoma Atractylodis Macrocephalae, 195-200 parts of lance asiabell root, 200-210 parts of Radix Isatidis, the achene of Siberian cocklebur
250-260 parts, 190-205 parts of the stem pith of the rice-paper plant.
5. the drug of swine flu is prevented and treated according to claim 1, it is characterized in that: 100 parts of rhizome of cyrtomium, 250 parts of radix bupleuri, radix saposhnikoviae 200
Part, 300 parts of Radix Astragali, 200 parts of Rhizoma Atractylodis Macrocephalae, 200 parts of lance asiabell root, 200 parts of Radix Isatidis, 250 parts of the achene of Siberian cocklebur, 200 parts of the stem pith of the rice-paper plant.
6. a kind of preparation method for the drug for preventing and treating swine flu, it is characterized in that: it mainly includes the following steps:
It is characterized by comprising following steps:
One, bulk pharmaceutical chemicals are weighed by proportion by weight；
Two, the bulk pharmaceutical chemicals claimed are crushed, is uniformly mixed, obtain the drug of prevention and treatment swine flu.
7. the preparation method of the drug of prevention and treatment swine flu according to claim 6, it is characterized in that: step 2 bulk pharmaceutical chemicals crush
Afterwards, 100-300 mesh is crossed.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811296240.5A CN109045102A (en) | 2018-11-01 | 2018-11-01 | A kind of drug and preparation method thereof for preventing and treating swine flu |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114468162A (en) * | 2022-02-25 | 2022-05-13 | 四川恒通动物营养科技有限公司 | Additive for enhancing immunity and reproductive performance of sows and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106692282A (en) * | 2016-12-27 | 2017-05-24 | 佛山瑞箭体育器材有限公司 | Medicine for preventing and treating swine influenza, and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106692282A (en) * | 2016-12-27 | 2017-05-24 | 佛山瑞箭体育器材有限公司 | Medicine for preventing and treating swine influenza, and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 赵志国等: "《考研中医复习精要》", 31 August 2018, 中国中医药出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114468162A (en) * | 2022-02-25 | 2022-05-13 | 四川恒通动物营养科技有限公司 | Additive for enhancing immunity and reproductive performance of sows and preparation method thereof |
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