CN109010808A - A kind of health care's food formula and preparation method thereof of reducing blood lipid prevention cardiovascular and cerebrovascular disease - Google Patents

A kind of health care's food formula and preparation method thereof of reducing blood lipid prevention cardiovascular and cerebrovascular disease Download PDF

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Publication number
CN109010808A
CN109010808A CN201811219696.1A CN201811219696A CN109010808A CN 109010808 A CN109010808 A CN 109010808A CN 201811219696 A CN201811219696 A CN 201811219696A CN 109010808 A CN109010808 A CN 109010808A
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parts
health care
blood lipid
cerebrovascular disease
reducing blood
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张文博
董伟夫
董树文
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Jilin Heng Shi Yi Chuan Food Science And Technology Development Co Ltd
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Jilin Heng Shi Yi Chuan Food Science And Technology Development Co Ltd
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/074Ganoderma
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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Abstract

The invention discloses a kind of health care's food formulas and preparation method thereof of reducing blood lipid prevention cardiovascular and cerebrovascular disease, belong to health care's food technology field, be intended to " preventive treatment of disease " using Chinese medicine thought prevention and treatment hyperlipidemia, the blood lipid level of mid-aged population is effectively reduced, avoids or reduces the generation of cardiovascular and cerebrovascular disease.The formula includes the raw material of following parts by weight: 5-20 parts of ganoderma lucidum, 5-20 parts of hawthorn, 1-10 parts of pueraria lobata, 5-20 parts of oyster, 10-30 parts of cassia seed, 1-10 parts of inulin and 0.3-3 parts of Nattokinase freeze-dried powder, this method include decoct, sedimentation, concentration and etc..The present invention is by being optimized to subassembly and dosage, novelty is by " integration of drinking and medicinal herbs " and " new raw-food material " scientific matching at health care's food, for adjusting blood lipid, reducing blood lipid level, avoid or reduce cardiovascular and cerebrovascular disease, reach the effect of " disease-free first to prevent; disease is early controls; both disease was preapred for an unfavorable turn of events, and was prevented after being ill multiple ".

Description

A kind of reducing blood lipid prevents health care's food formula and its preparation of cardiovascular and cerebrovascular disease Method
Technical field
The present invention relates to the technical fields of health care's food more particularly to a kind of reducing blood lipid to prevent cardiovascular and cerebrovascular disease Health care's food formula and preparation method thereof.
Background technique
With the rising of economic level, people's lives level is also stepped up, protein, heat, the rouge daily intaked The ingredients such as fat increase, in addition the pressure and bad habit of Working Life, activity is reduced, and cause the disease incidence of hyperlipidemia obvious Rise.Hyperlipidemia has bigger probability to cause atherosclerosis in cardiovascular and cerebrovascular disease morbidity crowd, there is 80% or more Patient has atherosclerosis.Therefore the prevention and treatment for reinforcing hyperlipidemia is extremely important.There are about 2 for dyslipidemia in population of China at present Hundred million patients become the disease incidence and case fatality rate rapid increase and in rejuvenation trend and the important original that increases of sudden death of China's coronary heart disease One of because, there is very high disability rate and lethality.It is conventional to be treated using tune lipid drug, though it is effective in cure, it needs long-term It takes, can just keep effect for reducing fat, it is big to the toxic side effect of liver kidney.Motherland medicine is of extensive knowledge and profound scholarship, and Chinese medicine thought of " preventiveing treatment of disease " exists Preventing and treating has good effect in hyperlipidemia, the blood lipid level of patient can be effectively reduced, effectively avoid or reduce heart and brain blood The generation of pipe disease.
Summary of the invention
The present invention is that Chinese medicine " is preventiveed treatment of disease " utilization of the thought in prevention and treatment hyperlipidemia, it is innovative by " integration of drinking and medicinal herbs " and " new raw-food material " scientific matching avoids or reduces the heart for adjusting blood lipid prevention cardiovascular and cerebrovascular disease at health care's food The incidence of cranial vascular disease reaches the effect of " disease-free first to prevent, disease is early controls, and both disease was preapred for an unfavorable turn of events, and was prevented after being ill multiple ".Therefore, this hair It is bright that a kind of health care's food formula and preparation method thereof of reducing blood lipid prevention cardiovascular and cerebrovascular disease is provided.
To achieve the goals above, the invention provides the following technical scheme:
A kind of health care's food formula of reducing blood lipid prevention cardiovascular and cerebrovascular disease, the raw material including following parts by weight: spirit 5-20 parts of sesame, 5-20 parts of hawthorn, 1-10 parts of pueraria lobata, 5-20 parts of oyster, 10-30 parts of cassia seed, 1-10 parts of inulin and Nattokinase 0.3-3 parts of freeze-dried powder.
Preferably, health care's food formula of above-mentioned reducing blood lipid prevention cardiovascular and cerebrovascular disease, including following parts by weight Raw material: 10 parts of ganoderma lucidum, 10 parts of hawthorn, 5 parts of pueraria lobata, 10 parts of oyster, 15 parts of cassia seed, 6 parts of inulin and Nattokinase freeze-dried powder 1 Part.
Preferably, health care's food formula of above-mentioned reducing blood lipid prevention cardiovascular and cerebrovascular disease, passes through routine techniques hand Section is prepared into paste, capsule, tablet and powder agent, oral solution or pulvis.
The present invention also provides above-mentioned reducing blood lipid prevention cardiovascular and cerebrovascular disease health care's food formula preparation method, The following steps are included:
(1) by raw material ganoderma lucidum, hawthorn, pueraria lobata, oyster, cassia seed (stir-fry), according to bulk pharmaceutical chemicals weight ratio weigh it respectively Qualified medicinal material;
It is put into togerther in Decocting pot by the parts by weight, 4~6 times of amount water is added and impregnate 4~6 hours;
(2) it decocts
Decoct for the first time: the medicinal material after step (1) is impregnated boils 1~3h, separates fried liquid;
Second of decoction: adding 2~4 times of water for the dregs of a decoction obtained by first time boiling, boils 1~2h and separates fried liquid;
Third time decocts: adding 1~3 times of boiling to boil 0.5~1.5h second of decoction gained dregs of a decoction and separates fried liquid;
(3) low temperature settles
By step (2), fried liquid merges three times, filtration, is put into fluid reservoir, stands 34~36h under the conditions of 8~10 DEG C of low temperature, Then siphon supernatant;
(4) it is concentrated
Supernatant obtained by step (3) is concentrated under reduced pressure, 80 mesh is dry, pulverize, obtains extract powder;
(5) inulin of the parts by weight, Nattokinase freeze-dried powder and step (4) extract powder are added in batch mixer together, It is sufficiently stirred, mixes, packs, 4~6g/ bags of health care's food to get reducing blood lipid prevention cardiovascular and cerebrovascular disease.
Preferably, the preparation method of health care's food formula of above-mentioned reducing blood lipid prevention cardiovascular and cerebrovascular disease, including Following steps:
(1) by raw material ganoderma lucidum, hawthorn, pueraria lobata, oyster, cassia seed (stir-fry), according to bulk pharmaceutical chemicals weight ratio weigh it respectively Qualified medicinal material;
It is put into togerther in Decocting pot by the parts by weight, 5 times of amount water is added and impregnate 5 hours;
(2) it decocts
Decoct for the first time: the medicinal material after step (1) is impregnated boils 2h, separates fried liquid;
Second of decoction: adding 3 times of water for the dregs of a decoction obtained by first time boiling, boils 1.5h and separates fried liquid;
Third time decocts: will decoct the gained dregs of a decoction for second and 2 times of boiling boiling 1h is added to separate fried liquid;
(3) low temperature settles
By step (2), fried liquid merges three times, filtration, is put into fluid reservoir, stands 34~36h under the conditions of 8~10 DEG C of low temperature, Then siphon supernatant;
(4) it is concentrated
Supernatant obtained by step (3) is concentrated under reduced pressure, 80 mesh is dry, pulverize, obtains extract powder;
(5) inulin of the parts by weight, Nattokinase freeze-dried powder and step (4) extract powder are added in batch mixer together, It is sufficiently stirred, mixes, packs, 5g/ bags of health care's food to get reducing blood lipid prevention cardiovascular and cerebrovascular disease.
Preferably, the cassia seed is the cassia seed by frying.
Health care's food of reducing blood lipid prevention cardiovascular and cerebrovascular disease of the invention, instructions of taking are as follows: 1 bag every time, daily 2 It is secondary, warm water delivery service.
Heretofore described ganoderma lucidum, it is sweet in flavor, it is mild-natured.Return heart, lung, liver and kidney channel have invigorating qi for tranquilization, relieving cough and asthma function Effect, has more than 2000 years history in China, the magical treasure for being considered as strengthening by means of tonics by successive dynasties medicine man, strengthening the body resistance to consolidate the constitution.Master contains Amino acid, polypeptide, protein, fungal lysozyme and carbohydrate (reduced sugar and polysaccharide), ergosterol, triterpenes, coumarin Glucoside, volatile oil, stearic acid, benzoic acid, alkaloid, vitamin B2 and C etc. twist neurasthenia, hyperlipidemia, the coronary heart disease heart Bitterly, the treatment of the degree of having nothing in common with each other such as arrhythmia cordis, Keshan disease, plateau uncomfortable diseases, hepatitis, Hemorrhagic fever, indigestion, tracheitis Effect, the present invention can play good control efficiency by the prescriptions such as ganoderma lucidum and hawthorn, cassia seed, to diseases such as hyperlipidemias.
Heretofore described hawthorn, sour, sweet, slightly warm in nature.Returns spleen, stomach, Liver Channel.Rich in flavone compound, vitamin C, amino acid isoreactivity ingredient and nutriment, have food digesting stomach fortifying, and scattered stasis changes turbid lipid-loweringing, blood pressure lowering, heart tonifying, the anti-heart Restrain the effect of uneven equal.
Pueraria lobata in the present invention, it is sweet in flavor, pungent, it is cool in nature.Returns spleen, stomach, lung channel.Rich in a variety of flavones ingredients, chief active at It is divided into daidzein, daidzin, Puerarin, Puerarin -7- xyloside, arachidic acid, starch etc., brings down a fever, promote the production of body fluid to quench thirst with expelling pathogenic factors from muscles and skin, Promoting eruption, Shengyang Zhixie, clearing and activating the channels and collaterals, relieving alcoholism, hypoglycemic, blood lipid is anti-inflammatory and other effects, can reduce serum cholesterol, reduces oil Three esters, and the symptoms such as Xiang Qiang, dizziness, headache that can improve hypertensive diabetes patient.
Heretofore described oyster, taste is salty, cold nature.Return liver, gallbladder, kidney channel, there are transquilization with heavy material, checking exuberance of yang and tonifying yin, softening hard masses The effect of dissipating bind.Oyster be in all foods containing zinc it is the most abundant (every 100g oyster, does not include the weight of shell, aqueous 87.1%, 71.2mg containing zinc is rich in zinc albuminate, generates synergistic effect with ganoderma lucidum, hawthorn, pueraria lobata, further promotes its effect.
Heretofore described cassia seed, sweet in flavor, bitter, salty, cold nature.Return liver, large intestine channel, containing multivitamin and enriches Amino acid, fat, carbohydrate etc., there is relax bowel and defecation, clear liver and improve vision, sharp water defaecation, laxative and blood pressure lowering, drop Blood lipid reduces the effect of cholesterol.Quality is crisp after stir-fry, is easy to crush and fried effective component.
Heretofore described inulin, using the short chain inulin of average degree of polymerization DP≤9, short chain inulin contains more monosaccharide And disaccharide, it can effectively reduce serum total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C), improve high density lipoprotein level White/ldl ratio rate improves status of blood lipid.In addition, inulin is that one kind not will lead to the raised carbon water of glucose in urine Compound.It will not be hydrolyzed into monosaccharide on the top of enteron aisle, because without increasing blood glucose level and insulin content.
Heretofore described Nattokinase is a kind of Proteinkinase, is in soybean isoflavone by natto strain by natto A kind of serine protease that hay bacillus (Bacillus subtilisl natto) generates.With thrombus, blood is reduced The effects of viscosity improves blood circulation, softens and increases blood vessel elasticity.Its molecular weight is far smaller than the protein of UK, SK, tPA, And can be absorbed by enteron aisle, the internal thrombolysis activity of Nattokinase is four times of fibrinolysin, in vivo the effect rapid, duration It is long, moreover it is possible to activate intracorporal tPA, be allowed to fibrinolytic that is mild, constantly improving blood, the cost compared with other thrombolytic drugs Low, the advantages that safety is good, molecular weight is small, oral result is good, thrombolysis activity is high, acting duration is long.
Compared with prior art, the invention has the benefit that
The present invention uses ganoderma lucidum, hawthorn, pueraria lobata, oyster, cassia seed (stir-fry), inulin and Nattokinase, by optimizing ingredient Combination and dosage, novelty will " integration of drinking and medicinal herbs " and " new raw-food material " scientific matching at health care's food, by immersion, more It is secondary decoct and etc. be prepared health care's food of prevention cardiovascular and cerebrovascular disease, compound various active substance and nutrition at Point, for adjusting blood lipid, blood glucose, prevents cardiovascular and cerebrovascular disease, avoid or reduce the incidence of cardiovascular and cerebrovascular disease, be Chinese medicine The thought of " preventiveing treatment of disease ", early prevention cardiovascular and cerebrovascular disease reach " disease-free first to prevent, disease is early controls, and both disease was preapred for an unfavorable turn of events, and was prevented after being ill multiple " Effect.
Specific embodiment
In order to make those skilled in the art more fully understand technical solution of the present invention, below in conjunction with embodiment to this Invention is further detailed.Raw material employed in embodiment, equipment etc. can pass through purchase in addition to particular determination Buyer's formula obtains.
1 reducing blood lipid of embodiment prevents the preparation of health care's food of cardiovascular and cerebrovascular disease
(1) qualified medicinal material ganoderma lucidum 5g, hawthorn 5g, pueraria lobata 1g, oyster 5g, cassia seed 10g are weighed;It is put into togerther Decocting pot In, 4 times of amount water are added and impregnate 6 hours;
(2) it decocts
Decoct for the first time: the medicinal material after step (1) is impregnated boils 1h, separates fried liquid;
Second of decoction: adding 2 times of water for the dregs of a decoction obtained by first time boiling, boils 2h and separates fried liquid;
Third time decocts: will decoct the gained dregs of a decoction for second and 3 times of boiling boiling 0.5h is added to separate fried liquid;
(3) low temperature settles
By step (2), fried liquid merges three times, and filtration is put into fluid reservoir, stands 36h under the conditions of 810 DEG C of low temperature, then rainbow Suct clear liquid;
(4) it is concentrated
Supernatant obtained by step (3) is concentrated under reduced pressure, 80 mesh is dry, pulverize, obtains extract powder;
(5) inulin 1g, Nattokinase freeze-dried powder 0.3g and step (4) extract powder are added in batch mixer together, are sufficiently stirred It mixes, mix, pack, 5g/ bags of health care's food to get reducing blood lipid prevention cardiovascular and cerebrovascular disease.
2 reducing blood lipid of embodiment prevents the preparation of health care's food of cardiovascular and cerebrovascular disease
(1) net cassia seed is taken, sets in preheating frying container, is heated with mild fire, frying to micro- has cracker, micro- to heave, inside Yellow, and when escaping fragrance, taking-up cools down, and the used time smashs to pieces.
Weigh qualified medicinal material ganoderma lucidum 10g, hawthorn 10g, pueraria lobata 5g, oyster 10g, cassia seed (stir-fry) 15g;It is put into togerther decoction In tank, 5 times of amount water are added and impregnate 5 hours;
(2) it decocts
Decoct for the first time: the medicinal material after step (1) is impregnated boils 2h, separates fried liquid;
Second of decoction: adding 3 times of water for the dregs of a decoction obtained by first time boiling, boils 1.5h and separates fried liquid;
Third time decocts: will decoct the gained dregs of a decoction for second and 2 times of boiling boiling 1h is added to separate fried liquid;
(3) low temperature settles
By step (2), fried liquid merges three times, and filtration is put into fluid reservoir, stands 36h under the conditions of 9 DEG C of low temperature, then siphon Supernatant;
(4) it is concentrated
Supernatant obtained by step (3) is concentrated under reduced pressure, 80 mesh is dry, pulverize, obtains extract powder;
(5) inulin 6g, Nattokinase freeze-dried powder 1g and step (4) extract powder are added in batch mixer together, be sufficiently stirred, Mixing, packaging, 5g/ bags of health care's food to get reducing blood lipid prevention cardiovascular and cerebrovascular disease.
3 reducing blood lipid of embodiment prevents the preparation of health care's food of cardiovascular and cerebrovascular disease
(1) net cassia seed is taken, sets in preheating frying container, is heated with mild fire, frying to micro- has cracker, micro- to heave, inside Yellow, and when escaping fragrance, taking-up cools down, and the used time smashs to pieces.
Weigh qualified medicinal material ganoderma lucidum 20g, hawthorn 20g, pueraria lobata 10g, oyster 20g, cassia seed (stir-fry) 30g;It is put into togerther pan-fried It boils in tank, 6 times of amount water is added and impregnate 4 hours;
(2) it decocts
Decoct for the first time: the medicinal material after step (1) is impregnated boils 3h, separates fried liquid;
Second of decoction: adding 4 times of water for the dregs of a decoction obtained by first time boiling, boils 1h and separates fried liquid;
Third time decocts: will decoct the gained dregs of a decoction for second and 1 times of boiling boiling 1.5h is added to separate fried liquid;
(3) low temperature settles
By step (2), fried liquid merges three times, and filtration is put into fluid reservoir, stands 34h under the conditions of 10 DEG C of low temperature, then rainbow Suct clear liquid;
(4) it is concentrated
Supernatant obtained by step (3) is concentrated under reduced pressure, 80 mesh is dry, pulverize, obtains extract powder;
(5) inulin 10g, Nattokinase freeze-dried powder 3g and step (4) extract powder are added in batch mixer together, are sufficiently stirred It mixes, mix, pack, 5g/ bags of health care's food to get reducing blood lipid prevention cardiovascular and cerebrovascular disease.
Further, it is also possible to which the reducing blood lipid of above-described embodiment step 5 is prevented cardiovascular and cerebrovascular disease by conventional technical means Health care's food be further prepared into the dosage forms such as capsule, tablet, pulvis or granule.
Test example 1
(1) method and data
Being diagnosed as hyperlipemia for 156, (age 46~60 years old, male patient 96 was female patient 60, total through detecting Cholesterol is all larger than 6mmol/L, and triglycerides is all larger than 2mmol/L) it is randomly divided into 4 groups, experimental group 1~3 and control group, often Group each 39, wherein severity extent compares no significant difference (P < 0.05) between group.Wherein, this hair is respectively adopted in experimental group 1~3 Health care's food of the reducing blood lipid prevention cardiovascular and cerebrovascular disease of bright Examples 1 to 3 preparation, it is daily 1 bag, twice daily, early Evening is each primary, and warm water is taken;Control group uses commercially available Lovastatin, and one time a day, each 20mg takes when dinner or before sleeping. 1 month is 1 course for the treatment of, and experimental group 1~3 and control group take 2 course for the treatment of, and counts knot after monthly checking blood lipid 1 time, 2 months Fruit.
Evaluation criterion are as follows:
Recovery from illness: recovery from illness refers to that symptom disappears, and lipid examination restores normal, and checks 3 times and do not increasing, wherein total gallbladder is solid Alcohol: 2.8~5.17mmol/L;Triglycerides: 0.56~1.7mmol/L;
Effective: including two kinds of situations: (1) symptom disappears, and lipid examination restores normal, and check can increase once again;(2) symptom Substantially reduced, lipid examination restores normally within 2 months, and check Chang Zaidu is increased;
Invalid: for symptom without substantially reduced, lipid examination restores normal yet in 2 months, even increase.
(2) experimental result
Experimental group 1: 31 (79.5%) of recovery from illness, it is effective 6 (15.4%), it is invalid 2 (5.1%), it is effective 37 total (94.9%);
Experimental group 2: 35 (89.7%) of recovery from illness, it is effective 3 (7.7%), it is invalid 1 (2.6%), it is effective 37 total (95.8%);
Experimental group 3: 33 (84.6%) of recovery from illness, it is effective 4 (10.3%), it is invalid 2 (5.1%), it is effective 37 total (94.9%);
Control group: 32 (82.1%) of recovery from illness, it is effective 5 (12.8%), it is invalid 2 (5.1%), it is effective 138 total (94.9%).
The case number of cases and case percentage number of results of comparison are as shown in table 1 below:
Table 1
It fully recovers (people) Effectively (people) (people) in vain Total effective rate (%)
Experimental group 1 31 6 2 94.9
Experimental group 2 35 3 1 95.8
Experimental group 3 33 4 2 94.9
Control group 32 5 2 94.9
According to data in table it is found that being comparable before and after treatment, experimental group is always effectively for greater than 37, control group always has Effect is 37, and the total significant figure of experimental group is more than or equal to the total significant figure of control group;Meanwhile total effective percentage of experimental group is 94.9%, total effective percentage of control group is 94.9%, is statistically analyzed test group and control group no significant difference (P > 0.05), for severity extent difference without clear meaning, balance between the two groups is preferable before treating, but the present invention is health care's food, long Phase using safe and free of toxic and side effects, i.e. the effect effect that is better than Lovastatin.
The above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations;Although with reference to the foregoing embodiments Invention is explained in detail, those skilled in the art should understand that: it still can be to aforementioned each implementation Example documented by technical solution modify perhaps equivalent replacement of some of the technical features but these modification or Replacement, the spirit and scope for technical solution of various embodiments of the present invention that it does not separate the essence of the corresponding technical solution.

Claims (6)

1. a kind of health care's food formula of reducing blood lipid prevention cardiovascular and cerebrovascular disease, which is characterized in that including following parts by weight Raw material: 5-20 parts of ganoderma lucidum, 5-20 parts of hawthorn, 1-10 parts of pueraria lobata, 5-20 parts of oyster, 10-30 parts of cassia seed, 1-10 parts of inulin and 0.3-3 parts of Nattokinase freeze-dried powder.
2. health care's food formula of reducing blood lipid prevention cardiovascular and cerebrovascular disease according to claim 1, which is characterized in that Raw material including following parts by weight: 10 parts of ganoderma lucidum, 10 parts of hawthorn, 5 parts of pueraria lobata, 10 parts of oyster, 15 parts of cassia seed, 6 parts of inulin and 1 part of Nattokinase freeze-dried powder.
3. health care's food formula of reducing blood lipid prevention cardiovascular and cerebrovascular disease according to claim 1 or 2, feature exist In being prepared into paste, capsule, tablet and powder agent, oral solution or pulvis by conventional technical means.
4. the preparation side of health care's food formula of reducing blood lipid prevention cardiovascular and cerebrovascular disease according to claim 1 or 2 Method, which comprises the following steps:
(1) by raw material ganoderma lucidum, hawthorn, pueraria lobata, oyster, cassia seed, according to bulk pharmaceutical chemicals weight ratio weigh its respective qualified medicine Material;
It is put into togerther in Decocting pot by the parts by weight, 4~6 times of amount water is added and impregnate 4~6 hours;
(2) it decocts
Decoct for the first time: the medicinal material after step (1) is impregnated boils 1~3h, separates fried liquid;
Second of decoction: adding 2~4 times of water for the dregs of a decoction obtained by first time boiling, boils 1~2h and separates fried liquid;
Third time decocts: adding 1~3 times of boiling to boil 0.5~1.5h second of decoction gained dregs of a decoction and separates fried liquid;
(3) low temperature settles
By step (2), fried liquid merges three times, filtration, is put into fluid reservoir, stands 34~36h under the conditions of 8~10 DEG C of low temperature, then Siphon supernatant;
(4) it is concentrated
Supernatant obtained by step (3) is concentrated under reduced pressure, 80 mesh is dry, pulverize, obtains extract powder;
(5) inulin of the parts by weight, Nattokinase freeze-dried powder and step (4) extract powder are added in batch mixer together, sufficiently Stirring, mixing, packaging, 4~6g/ bags of health care's food to get reducing blood lipid prevention cardiovascular and cerebrovascular disease.
5. the preparation method of health care's food formula of reducing blood lipid prevention cardiovascular and cerebrovascular disease according to claim 4, Characterized by comprising the following steps:
(1) by raw material ganoderma lucidum, hawthorn, pueraria lobata, oyster, cassia seed, according to bulk pharmaceutical chemicals weight ratio weigh its respective qualified medicine Material;
It is put into togerther in Decocting pot by the parts by weight, 5 times of amount water is added and impregnate 5 hours;
(2) it decocts
Decoct for the first time: the medicinal material after step (1) is impregnated boils 2h, separates fried liquid;
Second of decoction: adding 3 times of water for the dregs of a decoction obtained by first time boiling, boils 1.5h and separates fried liquid;
Third time decocts: will decoct the gained dregs of a decoction for second and 2 times of boiling boiling 1h is added to separate fried liquid;
(3) low temperature settles
By step (2), fried liquid merges three times, filtration, is put into fluid reservoir, stands 34~36h under the conditions of 8~10 DEG C of low temperature, then Siphon supernatant;
(4) it is concentrated
Supernatant obtained by step (3) is concentrated under reduced pressure, 80 mesh is dry, pulverize, obtains extract powder;
(5) inulin of the parts by weight, Nattokinase freeze-dried powder and step (4) extract powder are added in batch mixer together, sufficiently Stirring, mixing, packaging, 5g/ bags of health care's food to get reducing blood lipid prevention cardiovascular and cerebrovascular disease.
6. the preparation method of health care's food formula of prevention cardiovascular and cerebrovascular disease according to claim 5, feature It is, the cassia seed is the cassia seed by frying.
CN201811219696.1A 2018-10-19 2018-10-19 A kind of health care's food formula and preparation method thereof of reducing blood lipid prevention cardiovascular and cerebrovascular disease Pending CN109010808A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117797193A (en) * 2023-12-18 2024-04-02 广东药科大学 Composition for treating cardiovascular and cerebrovascular diseases and preparation method thereof

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102038257A (en) * 2009-10-22 2011-05-04 裘建社 Preparation method of cassia seed and kudzu root solid beverage
CN102068521A (en) * 2011-01-13 2011-05-25 南京苏美瑞医药科技有限公司 Traditional Chinese medicine composition for treating hyperlipidemia and preparation method and application thereof
CN102106429A (en) * 2011-01-19 2011-06-29 四川回春堂生物科技有限公司 Cassia seed lipid-lowering tea and preparation method thereof
CN102716471A (en) * 2012-07-03 2012-10-10 童长虹 Anti-hyperlipidemia health-care product
CN104491053A (en) * 2014-12-03 2015-04-08 唐逍 Traditional Chinese medicine preparation for preventing and treating cardiovascular as well as cerebrovascular diseases and preparation method thereof
CN105412279A (en) * 2015-12-30 2016-03-23 天津嘉氏堂科技有限公司 Blood-fat-reducing traditional Chinese medicine health care product
CN107343896A (en) * 2016-05-06 2017-11-14 焦趁英 A kind of tea for reducing blood fat and blood pressure
CN107467287A (en) * 2016-06-07 2017-12-15 雒成林 A kind of tea for reducing hypertension and fat

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102038257A (en) * 2009-10-22 2011-05-04 裘建社 Preparation method of cassia seed and kudzu root solid beverage
CN102068521A (en) * 2011-01-13 2011-05-25 南京苏美瑞医药科技有限公司 Traditional Chinese medicine composition for treating hyperlipidemia and preparation method and application thereof
CN102106429A (en) * 2011-01-19 2011-06-29 四川回春堂生物科技有限公司 Cassia seed lipid-lowering tea and preparation method thereof
CN102716471A (en) * 2012-07-03 2012-10-10 童长虹 Anti-hyperlipidemia health-care product
CN104491053A (en) * 2014-12-03 2015-04-08 唐逍 Traditional Chinese medicine preparation for preventing and treating cardiovascular as well as cerebrovascular diseases and preparation method thereof
CN105412279A (en) * 2015-12-30 2016-03-23 天津嘉氏堂科技有限公司 Blood-fat-reducing traditional Chinese medicine health care product
CN107343896A (en) * 2016-05-06 2017-11-14 焦趁英 A kind of tea for reducing blood fat and blood pressure
CN107467287A (en) * 2016-06-07 2017-12-15 雒成林 A kind of tea for reducing hypertension and fat

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王晶等: "降脂茶辅助治疗血脂异常的临床研究进展", 《中医药导报》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117797193A (en) * 2023-12-18 2024-04-02 广东药科大学 Composition for treating cardiovascular and cerebrovascular diseases and preparation method thereof

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