CN107198767A - It is a kind of to be used to prevent three high red yeast rice balsam pear complex peptides pieces - Google Patents
It is a kind of to be used to prevent three high red yeast rice balsam pear complex peptides pieces Download PDFInfo
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- CN107198767A CN107198767A CN201710358964.7A CN201710358964A CN107198767A CN 107198767 A CN107198767 A CN 107198767A CN 201710358964 A CN201710358964 A CN 201710358964A CN 107198767 A CN107198767 A CN 107198767A
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- red yeast
- yeast rice
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- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
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Abstract
It is used to prevent three high red yeast rice balsam pear complex peptides pieces, including following component the invention provides a kind of：The oligomeric Gly-His-Lys of wheat, soy peptide powder, collagen Gly-His-Lys, albumin Gly-His-Lys, polydextrose, oligoisomaltose, inulin, red yeast rice, Bitter Melon P.E, ginkgo powder, Tea Polyphenols.Not only palatability is good for this product, and has more significant effect to the symptom improvement of the three high patients.
Description
Technical field
The invention belongs to a kind of health care field of medicaments, particularly belong to a kind of for preventing three high red yeast rice balsam pear complex peptides
Piece.
Background technology
" three high diseases " refer to hypertension, hyperglycaemia (diabetes) and hyperlipidemia.They are that modern society is derived from
" rich man's disease ", possible individualism, it is also possible to interrelated.Such as：Diabetes patient is easy to while suffering from hypertension or high blood
Fat disease, and high fat of blood is the principal element of artery sclerosis formation and development, arteriosclerotic's blood vessel elasticity difference aggravation blood pressure
Rise.So, there are any one of these three illness, the later stage all easily forms " three high diseases ".
(1) hypertension
High blood pressure is one of contemporary most common epidemic disease, early high blood pressure patient can show headache, dizziness, tinnitus,
The symptoms such as palpitaition, dim eyesight, absent minded, failure of memory, numbness in hands and feet, fatigue and weak, easy agitation, these symptoms are generally
Caused by higher nerve functional disturbance, its weight increases degree with blood pressure can be inconsistent.
Later stage blood pressure often continues in higher level, and with the performance of the impaired organs such as brain, the heart, kidney.These impaired organs
Can be that hypertension is directly damaged causing or caused indirectly by accelerating atherosclerosis to produce
's.The early stage of these impaired organs can be asymptomatic, finally results in dysfunction, or even occur exhaustion.
(2) hyperglycaemia
Most common hyperglycemia is diabetes.Diabetes are a kind of chronic, lifelong diseases, are a kind of serious harm people
The common disease of body health, because insulin is relative or definitely not enough, makes the nutrients such as internal carbohydrate, fat, protein
Metabolic disorder.This disease can cause multiple complications, and systemic disease can be caused when serious, make one to disable, blinding, or even cause
Extremely.The symptom of diabetes is " three-many-one-little ", i.e. diuresis, many drinks, many foods and Body weight loss.Hyperglycemia patient is it is noted that control drink
Food, low sugar less salt is strengthened taking exercise, if having a blood test sugar or height again after a time, is also considered as with hypoglycemic medicine.
(3) high fat of blood
High fat of blood refers to blood cholesterol or triglycerides is too high or HDL-C is too low, and modern medicine claims
Be dyslipidemia.If hyperlipemia, " blood is thick " is easily caused, is deposited on vascular wall, gradually forms atherosclerosis,
Blood vessel is gradually blocked, makes blood flow slack-off, blood flow is interrupted when serious.
Such case will cause coronary heart disease in the event of in heart；Headstroke occurs in brain in generation；If blocked
Optical fundus blood vessel, will cause visual impairment, blindness；In the event of in kidney, renal arteriosclerosis, renal failure will be caused；Hair
It is raw in lower limb, it may appear that limb necrosis, fester.In addition, high fat of blood can trigger hypertension, induce gall stone, pancreatitis, aggravate
The diseases such as hepatitis, senile dementia.Want reducing blood lipid to eat the material of VITAMIN C TABLET, ginkgo soft capsule, liquid calcium etc more.
The clinical prevention high to three, typically now with Western medicine reducing pressure and sugar lipid-lowering medicine, the general side effect of these medicines is big, past
Just need to take throughout one's life toward once taking, it is impossible to reach the purpose treated both principal and secondary aspect of disease, and some medicines also have withdrawal reaction, so,
How Basic Theories of Chinese Medicine is utilized, with reference to the advantage of Chinese medicine, invent a kind of Chinese medicine or health products evident in efficacy, Small side effects
The problem of as clinical urgent need to resolve.
The content of the invention
Technical problem：The present invention is used to prevent three high red yeast rice balsam pears to be combined for the symptom of three high crowds there is provided a kind of
Peptide piece.
Technical scheme：The present invention provides a kind of for preventing three high red yeast rice balsam pear complex peptides pieces, including following raw material：It is small
The oligomeric Gly-His-Lys of wheat, soy peptide powder, collagen Gly-His-Lys, albumin Gly-His-Lys, polydextrose, oligoisomaltose, inulin, red yeast rice,
Bitter Melon P.E, ginkgo powder, Tea Polyphenols.
As a preferred embodiment, each raw material weight proportioning of soup processed is as follows：Oligomeric Gly-His-Lys 15-25 parts of wheat, 15-25 parts of soy peptide powder,
2-6 parts of collagen Gly-His-Lys, 1-3 parts of albumin Gly-His-Lys, 5-9 parts of polydextrose, 8-12 parts of oligoisomaltose, 2-5 parts of inulin,
3-12 parts of red yeast rice, 3-12 parts of Bitter Melon P.E, 2-6 parts of ginkgo powder, 0.15-1.25 parts of Tea Polyphenols.
As further preferred：Each raw material weight proportioning of soup processed is as follows：20 parts of the oligomeric Gly-His-Lys of wheat, 20 parts of soy peptide powder, collagen
4 parts of protein peptide powder, 2 parts of albumin Gly-His-Lys, 7.5 parts of polydextrose, 9.75 parts of oligoisomaltose, 3.75 parts of inulin, red yeast rice 7.5
Part, 7.5 parts of Bitter Melon P.E, 4.5 parts of ginkgo powder, 0.75 part of Tea Polyphenols.
Beneficial effect：This formula can effectively prevent three high, while reducing the sense of discomfort taken, effect relaxes, no secondary to make
With.
The oligomeric Gly-His-Lys of wheat：The blood glucose of adjustable people, improvement diabetic symptom, the effect of energy line artery Angiotensin Converting Enzyme enzyme,
Effect with hypotensive, containing high glutamine, can effectively adjust nerve, can make special dietary material during intestinal dysfunction.
Soy peptide powder：Nutritious, human body easily absorbs, and also with anti-hypertension, reduction cholesterol, antithrombus formation, changes
Kind lipid-metabolism, promotes flesh red blood cell to restore, the regulatory function such as dispelling fatigue.
Collagen Gly-His-Lys：Vascular wall metabolism can be accelerated, increase vessel wall elasticity.
Albumin Gly-His-Lys：Plasma osmolarity, increase blood volume can be maintained.
Red yeast rice rice extracts：Reduce cholesterol effect good.
Bitter Melon P.E：It is known as glucokinin, with good effect of lowering blood sugar, has no toxic side effect.
Embodiment
Beneficial effects of the present invention are expanded on further below by experiment, the present invention is expanded on further by embodiment.
This experimental raw medicine source producer and model such as following table：
| Nomenclature of drug | Manufacturer |
| The oligomeric Gly-His-Lys of wheat | Shandong Tianjiu Biotechnology Co., Ltd. |
| Soy peptide powder | Nuo Li such as one (Anyang) bio tech ltd |
| Collagen Gly-His-Lys | Shandong Tianjiu Biotechnology Co., Ltd. |
| Albumin Gly-His-Lys | Shandong Tianjiu Biotechnology Co., Ltd. |
| Polydextrose | The Long Chuanyuan bio tech ltd of Shandong hundred |
| Oligoisomaltose | The Long Chuanyuan bio tech ltd of Shandong hundred |
| Inulin | Shaanxi Sen Fu natural products Co., Ltd |
| Bitter Melon P.E | Shaanxi Sen Fu natural products Co., Ltd |
| Ginkgo powder | Shaanxi Sen Fu natural products Co., Ltd |
Embodiment 1
Prevent three high red yeast rice balsam pear complex peptides pieces, each raw material weight proportioning of soup processed is as follows：15 parts of the oligomeric Gly-His-Lys of wheat, Soybean Peptide
15 parts of powder, 2 parts of collagen Gly-His-Lys, 1 part of albumin Gly-His-Lys, 5 parts of polydextrose, 8 parts of oligoisomaltose, 2 parts of inulin, red yeast rice
3 parts, 3 parts of Bitter Melon P.E, 2 parts of ginkgo powder, 0.15 part of Tea Polyphenols.
Its preparation process, comprises the following steps：
Weigh 15 parts of the oligomeric Gly-His-Lys of wheat, 15 parts of soy peptide powder, 2 parts of collagen Gly-His-Lys, 1 part of albumin Gly-His-Lys, poly- Portugal
5 parts of grape sugar, 8 parts of oligoisomaltose, 2 parts of inulin, 3 parts of red yeast rice, 3 parts of Bitter Melon P.E, 2 parts of ginkgo powder, 0.15 part of Tea Polyphenols,
Mix to obtain total mixed powder；Pure water is added in total mixed powder, softwood is obtained；Softwood is pelletized with 40 mesh sieves, wet granular is obtained；Will be wet
Particle is dried to moisture ＜ 5% at 60 DEG C, and 40 mesh sieve whole grains obtain dry particl；By dry particl tabletting, tablet, 600mg/ pieces are obtained.
Embodiment 2
Prevent three high red yeast rice balsam pear complex peptides pieces, each raw material weight proportioning of soup processed is as follows：20 parts of the oligomeric Gly-His-Lys of wheat, Soybean Peptide
20 parts of powder, 4 parts of collagen Gly-His-Lys, 2 parts of albumin Gly-His-Lys, 7.5 parts of polydextrose, 9.75 parts of oligoisomaltose, inulin
3.75 parts, 7.5 parts of red yeast rice, 7.5 parts of Bitter Melon P.E, 4.5 parts of ginkgo powder, 0.75 part of Tea Polyphenols.
Its preparation process, comprises the following steps：
Weigh 20 parts of the oligomeric Gly-His-Lys of wheat, 20 parts of soy peptide powder, 4 parts of collagen Gly-His-Lys, 2 parts of albumin Gly-His-Lys, poly- Portugal
7.5 parts of grape sugar, 9.75 parts of oligoisomaltose, 3.75 parts of inulin, 7.5 parts of red yeast rice, 7.5 parts of Bitter Melon P.E, ginkgo powder 4.5
Part, 0.75 part of Tea Polyphenols, mix to obtain total mixed powder；Pure water is added in total mixed powder, softwood is obtained；By softwood with 40 mesh sieve series
Grain, obtains wet granular；Wet granular is dried to moisture ＜ 5% at 60 DEG C, 40 mesh sieve whole grains obtain dry particl；By dry particl tabletting, obtain
Tablet, 600mg/ pieces.
Embodiment 3
Prevent three high red yeast rice balsam pear complex peptides pieces, each raw material weight proportioning of soup processed is as follows：25 parts of the oligomeric Gly-His-Lys of wheat, Soybean Peptide
It is 25 parts of powder, 6 parts of collagen Gly-His-Lys, 3 parts of albumin Gly-His-Lys, 9 parts of polydextrose, 12 parts of oligoisomaltose, 5 parts of inulin, red
Bent 12 parts, 12 parts of Bitter Melon P.E, 6 parts of ginkgo powder, 1.25 parts of Tea Polyphenols.
Its preparation process, comprises the following steps：
Weigh 25 parts of the oligomeric Gly-His-Lys of wheat, 25 parts of soy peptide powder, 6 parts of collagen Gly-His-Lys, 3 parts of albumin Gly-His-Lys, poly- Portugal
9 parts of grape sugar, 12 parts of oligoisomaltose, 5 parts of inulin, 12 parts of red yeast rice, 12 parts of Bitter Melon P.E, 6 parts of ginkgo powder, Tea Polyphenols 1.25
Part, mix to obtain total mixed powder；Pure water is added in total mixed powder, softwood is obtained；Softwood is pelletized with 40 mesh sieves, wet granular is obtained；
Wet granular is dried to moisture ＜ 5% at 60 DEG C, 40 mesh sieve whole grains obtain dry particl；By dry particl tabletting, tablet, 600mg/ are obtained
Piece.
Comparative example 1
Prevent three high red yeast rice balsam pear complex peptides pieces, each raw material weight proportioning of soup processed is as follows：40 parts of the oligomeric Gly-His-Lys of wheat, collagen egg
White 4 parts of Gly-His-Lys, 2 parts of albumin Gly-His-Lys, 7.5 parts of polydextrose, 9.75 parts of oligoisomaltose, 3.75 parts of inulin, red yeast rice 7.5
Part, 7.5 parts of Bitter Melon P.E, 4.5 parts of ginkgo powder, 0.75 part of Tea Polyphenols.
Its preparation process, comprises the following steps：
Weigh 40 parts of the oligomeric Gly-His-Lys of wheat, it is 4 parts of collagen Gly-His-Lys, 2 parts of albumin Gly-His-Lys, 7.5 parts of polydextrose, oligomeric
9.75 parts of isomaltose, 3.75 parts of inulin, 7.5 parts of red yeast rice, 7.5 parts of Bitter Melon P.E, 4.5 parts of ginkgo powder, 0.75 part of Tea Polyphenols,
Mix to obtain total mixed powder；Pure water is added in total mixed powder, softwood is obtained；Softwood is pelletized with 40 mesh sieves, wet granular is obtained；Will be wet
Particle is dried to moisture ＜ 5% at 60 DEG C, and 40 mesh sieve whole grains obtain dry particl；By dry particl tabletting, tablet, 600mg/ pieces are obtained.
Comparative example 2
Prevent three high red yeast rice balsam pear complex peptides pieces, each raw material weight proportioning of soup processed is as follows：40 parts of soy peptide powder, collagen peptide
4 parts of powder, 2 parts of albumin Gly-His-Lys, 7.5 parts of polydextrose, 9.75 parts of oligoisomaltose, 3.75 parts of inulin, 7.5 parts of red yeast rice, hardship
7.5 parts of melon extract, 4.5 parts of ginkgo powder, 0.75 part of Tea Polyphenols.
Its preparation process, comprises the following steps：
Weigh 40 parts of soy peptide powder, 4 parts of collagen Gly-His-Lys, 2 parts of albumin Gly-His-Lys, 7.5 parts of polydextrose, oligomeric different wheat
9.75 parts of bud sugar, 3.75 parts of inulin, 7.5 parts of red yeast rice, 7.5 parts of Bitter Melon P.E, 4.5 parts of ginkgo powder, 0.75 part of Tea Polyphenols, mixing
Obtain total mixed powder；Pure water is added in total mixed powder, softwood is obtained；Softwood is pelletized with 40 mesh sieves, wet granular is obtained；By wet granular
Dried at 60 DEG C to moisture ＜ 5%, 40 mesh sieve whole grains obtain dry particl；By dry particl tabletting, tablet, 600mg/ pieces are obtained.
Comparative example 3
Prevent three high red yeast rice balsam pear complex peptides pieces, each raw material weight proportioning of soup processed is as follows：25 parts of the oligomeric Gly-His-Lys of wheat, Soybean Peptide
25 parts of powder, 6 parts of collagen Gly-His-Lys, 3 parts of albumin Gly-His-Lys, 12 parts of oligoisomaltose, 5 parts of inulin, 12 parts of red yeast rice, balsam pear are carried
Take 12 parts of thing, 6 parts of ginkgo powder, 1.25 parts of Tea Polyphenols.
Its preparation process, comprises the following steps：
Weigh 25 parts of the oligomeric Gly-His-Lys of wheat, it is 25 parts of soy peptide powder, 6 parts of collagen Gly-His-Lys, 3 parts of albumin Gly-His-Lys, oligomeric
12 parts of isomaltose, 5 parts of inulin, 12 parts of red yeast rice, 12 parts of Bitter Melon P.E, 6 parts of ginkgo powder, 1.25 parts of Tea Polyphenols, mix always
Mixed powder；Pure water is added in total mixed powder, softwood is obtained；Softwood is pelletized with 40 mesh sieves, wet granular is obtained；By wet granular 60
DEG C dry to moisture ＜ 5%, 40 mesh sieve whole grains obtain dry particl；By dry particl tabletting, tablet, 600mg/ pieces are obtained.
Pharmacodynamic experiment
This product can decoction, be taken after being infused in hot water or decoction, powder, particle, tablets and other formulations.
Drug test
General information：
Fetch and examine the high case of hypertension, hyperglycaemia, high fat of blood three 500, the age between 25-75, average age 53.6
Year.
Diagnostic criteria
High fat of blood：Reference《New Chinese medicine guideline of clinical investigations》With 2007《Blood Lipid Abnormality in Chinese Adults preventing and treating refers to
South》Standard is evaluated.
Hypertension：Clinical diagnosis meets standard as defined in the World Health Organization (WTO), that is, basic blood pressure is more than before preventing
Equal to 160/95mmHg.
Hyperglycaemia：With reference to WTOT2DM diagnostic criteria in 1999, tcm diagnosis standard reference《New Chinese medicine clinical research refers to
Lead principle (tentative)》In the Standards of Chinese Medical Syndrome Differentiation quenched one's thirst.
Instructions of taking
The medicine of the embodiment of the present invention 1 to 3 and comparative example 1 to 3 is taken, each 10g is 2 times a day taken after being infused in hot water or decoction, taken in two times
With being within 1 month further consultation after course for the treatment of, 2 courses for the treatment of, check preventive effect.
Efficacy result
As seen from the above table：The red yeast rice balsam pear complex peptides piece of this formula effect in terms of three height are prevented is notable.
Claims (3)
1. a kind of be used to prevent three high red yeast rice balsam pear complex peptides pieces, it is characterised in that：Including following component：Wheat oligopeptide
Powder, soy peptide powder, collagen Gly-His-Lys, albumin Gly-His-Lys, polydextrose, oligoisomaltose, inulin, red yeast rice, balsam pear are extracted
Thing, ginkgo powder, Tea Polyphenols.
2. it is according to claim 1 a kind of for preventing three high red yeast rice balsam pear complex peptides pieces, it is characterised in that：Each component
Parts by weight are as follows：Oligomeric Gly-His-Lys 15-25 parts of wheat, 15-25 parts of soy peptide powder, 2-6 parts of collagen Gly-His-Lys, albumin Gly-His-Lys 1-
3 parts, 5-9 parts of polydextrose, 8-12 parts of oligoisomaltose, 2-5 parts of inulin, 3-12 parts of red yeast rice, 3-12 parts of Bitter Melon P.E, silver
2-6 parts of apricot powder, 0.15-1.25 parts of Tea Polyphenols.
3. it is a kind of for preventing three high red yeast rice balsam pear complex peptides pieces according to claims 1 or 2, it is characterised in that：
Each component parts by weight are as follows：20 parts of the oligomeric Gly-His-Lys of wheat, 20 parts of soy peptide powder, 4 parts of collagen Gly-His-Lys, 2 parts of albumin Gly-His-Lys,
7.5 parts of polydextrose, 9.75 parts of oligoisomaltose, 3.75 parts of inulin, 7.5 parts of red yeast rice, 7.5 parts of Bitter Melon P.E, ginkgo powder
4.5 parts, 0.75 part of Tea Polyphenols.
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Cited By (5)
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| CN107668704A (en) * | 2017-09-30 | 2018-02-09 | 太原华欣康中医门诊部 | A kind of composition |
| CN107712914A (en) * | 2017-11-20 | 2018-02-23 | 中食都庆（山东）生物技术有限公司 | A kind of compound product with lipid-reducing function and preparation method thereof |
| CN108617957A (en) * | 2018-05-10 | 2018-10-09 | 丽睿客信息科技（北京）有限公司 | Nutraceutical with fat-reducing effect |
| CN110115757A (en) * | 2019-06-18 | 2019-08-13 | 中食都庆（山东）生物技术有限公司 | A kind of ginkgo biloba p.e and beans peptide compound antihypelipidemic preparation and preparation method thereof |
| CN110881666A (en) * | 2019-12-12 | 2020-03-17 | 西咸新区优恩生物科技股份有限公司 | Small molecule compound peptide preparation for special nutritional physique of astronaut |
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| CN104397188A (en) * | 2014-12-04 | 2015-03-11 | 保龄宝生物股份有限公司 | Low-calorie solid milk tea containing prebiotics and preparation method of solid milk tea |
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| CN101507494A (en) * | 2009-02-12 | 2009-08-19 | 刘志伟 | Special diet food for patient with hyperlipidemia and hypertension |
| CN102600227A (en) * | 2012-03-05 | 2012-07-25 | 吴江谷力生物科技有限公司 | Compound functional red rice capsule |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107668704A (en) * | 2017-09-30 | 2018-02-09 | 太原华欣康中医门诊部 | A kind of composition |
| CN107712914A (en) * | 2017-11-20 | 2018-02-23 | 中食都庆（山东）生物技术有限公司 | A kind of compound product with lipid-reducing function and preparation method thereof |
| CN108617957A (en) * | 2018-05-10 | 2018-10-09 | 丽睿客信息科技（北京）有限公司 | Nutraceutical with fat-reducing effect |
| CN110115757A (en) * | 2019-06-18 | 2019-08-13 | 中食都庆（山东）生物技术有限公司 | A kind of ginkgo biloba p.e and beans peptide compound antihypelipidemic preparation and preparation method thereof |
| CN110881666A (en) * | 2019-12-12 | 2020-03-17 | 西咸新区优恩生物科技股份有限公司 | Small molecule compound peptide preparation for special nutritional physique of astronaut |
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Application publication date: 20170926 |