CN109010097A - A kind of stain removing toothpaste and preparation method thereof - Google Patents
A kind of stain removing toothpaste and preparation method thereof Download PDFInfo
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- CN109010097A CN109010097A CN201811214362.5A CN201811214362A CN109010097A CN 109010097 A CN109010097 A CN 109010097A CN 201811214362 A CN201811214362 A CN 201811214362A CN 109010097 A CN109010097 A CN 109010097A
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- chelating agent
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- sorbierite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/463—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8158—Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- Public Health (AREA)
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- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
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- Oral & Maxillofacial Surgery (AREA)
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- Cosmetics (AREA)
Abstract
The invention discloses a kind of stain removing toothpastes and preparation method thereof；Stain removing toothpaste includes the raw material of following parts by weight: 20-30 parts of sorbierite, 2-6 parts of lauryl sodium sulfate, 8-12 parts of tfe polymer chelating agent, 6-10 parts of aster, 4-6 parts of ardisia japonica, 2-4 parts of duckweed, 0.3-0.7 parts of Fructus Aurantii；The present invention uses tfe polymer chelating agent and Chinese medical extract for raw material, it is non-stimulated to oral mucosa and tooth, stain-removing effect is good, it can effectively remove caused by long-term smoking is had tea that tooth is solid and discoloration problem, oral bacteria can also effectively be controlled, keep implication more pure and fresh, reduces bleeding gums, brilliant white tooth；Preparation process of the present invention is simple, and raw material sources are extensive, it is easy to accomplish industrialized production is worthy to be popularized.
Description
Technical field
The present invention relates to a kind of toothpaste, specifically a kind of stain removing toothpaste and preparation method thereof.
Background technique
As life improves, people more focus on personal hygiene and health problem, and oral problem increasingly receives in recent years
Pay attention to.There are many tiny holes for dental surface, and those pigment moleculars will penetrate into this some holes in our daily diet
It in hole, is attached on dentine, forms tooth stain, and bacterium also can constantly assemble in dental surface, form one layer of mucous membrane, formed
Plaque, removing are also easy to lead to calculus dentalis not in time, eventually lead to tooth and lesion occurs for root of the tooth, saprodontia occur, gum is swollen
Bitterly, dentine hypersensitivity, the symptoms such as bleeding gums.
Occur various stain removing toothpastes currently on the market, can improve dental plaque keeps tooth brilliant white healthy, but its effect is former
Reason is made a return journey stain tooth-whitening by increasing friction, absorption or photocatalysis mode, goes stain ability limited, and portioned product is in order to improve
It goes stain ability that harsh chemicals are added, is easy to cause adverse reaction to oral mucosa and tooth, often lose more than gain.
Summary of the invention
The purpose of the present invention is to provide a kind of stain removing toothpastes and preparation method thereof, to solve to propose in above-mentioned background technique
The problem of.
To achieve the above object, the invention provides the following technical scheme:
A kind of stain removing toothpaste, the raw material including following parts by weight: 20-30 parts of sorbierite, lauryl sodium sulfate 2-6
Part, 8-12 parts of tfe polymer chelating agent, 6-10 parts of aster, 4-6 parts of ardisia japonica, 2-4 parts of duckweed, 0.3-0.7 parts of Fructus Aurantii；
The structural formula of tfe polymer chelating agent are as follows:
In formula: x is the integer of 40-60, and y is the integer of 400-600.
As a further solution of the present invention: the raw material including following parts by weight: 23-27 parts of sorbierite, dodecyl
3-5 parts of sodium sulphate, 9-11 parts of tfe polymer chelating agent, 7-9 parts of aster, 4.5-5.5 parts of ardisia japonica, 2.5-3.5 parts of duckweed, Fructus Aurantii
0.4-0.6 parts.
As a further solution of the present invention: the raw material including following parts by weight: 25 parts of sorbierite, dodecyl sulphate
4 parts of sodium, 10 parts of tfe polymer chelating agent, 8 parts of aster, 5 parts of ardisia japonica, 3 parts of duckweed, 0.5 part of Fructus Aurantii.
A kind of preparation method of stain removing toothpaste, comprising the following steps:
(1) aster and duckweed are weighed by weight, and the mixed-powder that partial size is 50-150 μm is ground into after freeze-drying；
(2) ardisia japonica and Fructus Aurantii are weighed by weight, is ground into fine powder, crosses 50 meshes, and 1-3 times of volumetric concentration, which is added, is
50% ethanol solution filters after ultrasonic extraction, obtains filtrate；
(3) step (2) filtrate is warming up to 85-95 DEG C, step (1) mixed-powder is added under stirring condition, continues to stir
20-30min is cooled to 40-60 DEG C of addition tfe polymer chelating agent and sorbierite, continues to stir 1-2h；
(4) it is added in Manufacturing medicine extract machine after mixing step (3) gains and lauryl sodium sulfate, filling after cream processed, sterilization,
It seals to obtain the final product.
As a further solution of the present invention: freeze-drying temperature is subzero 12 degrees Celsius to subzero 8 in the step (1)
Degree Celsius, the mixed-powder that partial size is 100 μm is obtained after crushing.
As a further solution of the present invention: ultrasonic temperature is 73-77 DEG C in the step (2), ultrasonic power 480-
520W, ultrasonic time 25-35min.
As a further solution of the present invention: step (2) filtrate being warming up to 90 DEG C in the step (3), mixing speed
For step (1) mixed-powder is added under the conditions of 550-650rpm, continues to stir 25min, be cooled to 50 DEG C of addition tfe polymer chelas
Mixture and sorbierite continue to stir 1.5h.
Compared with prior art, the beneficial effects of the present invention are: using tfe polymer chelating agent and Chinese medical extract for original
Material, non-stimulated to oral mucosa and tooth, stain-removing effect is good, can effectively remove long-term smoking have tea caused by tooth it is solid and become
Color problem can also effectively control oral bacteria, keep implication more pure and fresh, reduce bleeding gums, brilliant white tooth；Present invention preparation
Simple process, raw material sources are extensive, it is easy to accomplish industrialized production is worthy to be popularized.
Specific embodiment
The technical solution of the patent is explained in further detail With reference to embodiment.
Embodiment 1
A kind of stain removing toothpaste, the raw material including following parts by weight: 20-30 parts of sorbierite, lauryl sodium sulfate 2-6
Part, 8-12 parts of tfe polymer chelating agent, 6-10 parts of aster, 4-6 parts of ardisia japonica, 2-4 parts of duckweed, 0.3-0.7 parts of Fructus Aurantii；
The structural formula of tfe polymer chelating agent are as follows:
In formula: x 40, y 400.
A kind of preparation method of stain removing toothpaste, comprising the following steps:
(1) aster and duckweed are weighed by weight, and it is 50 μm that partial size is ground into after being freeze-dried under subzero 12 degrees Celsius
Mixed-powder；
(2) ardisia japonica and Fructus Aurantii are weighed by weight, is ground into fine powder, crosses 50 meshes, and it is 50% that 1 times of volumetric concentration, which is added,
Ethanol solution, filter after ultrasonic extraction, obtain filtrate, ultrasonic temperature is 73 DEG C, ultrasonic power 480W, and ultrasonic time is
25min；
(3) step (2) filtrate being warming up to 85 DEG C, step (1) mixed-powder is added under the conditions of being 550rpm in mixing speed,
Continue to stir 20min, be cooled to 40 DEG C of addition tfe polymer chelating agents and sorbierite, continues to stir 1h；
(4) it is added in Manufacturing medicine extract machine after mixing step (3) gains and lauryl sodium sulfate, filling after cream processed, sterilization,
It seals to obtain the final product.
Embodiment 2
A kind of stain removing toothpaste, the raw material including following parts by weight: 23-27 parts of sorbierite, lauryl sodium sulfate 3-5
Part, 9-11 parts of tfe polymer chelating agent, 7-9 parts of aster, 4.5-5.5 parts of ardisia japonica, 2.5-3.5 parts of duckweed, Fructus Aurantii 0.4-0.6
Part；
The structural formula of tfe polymer chelating agent are as follows:
In formula: x 45, y 450.
A kind of preparation method of stain removing toothpaste, comprising the following steps:
(1) aster and duckweed are weighed by weight, and it is 75 μm that partial size is ground into after being freeze-dried under subzero 11 degrees Celsius
Mixed-powder；
(2) ardisia japonica and Fructus Aurantii are weighed by weight, is ground into fine powder, cross 50 meshes, 1.5 times of volumetric concentrations, which are added, is
50% ethanol solution filters after ultrasonic extraction, obtains filtrate, and ultrasonic temperature is 74 DEG C, ultrasonic power 490W, and ultrasonic time is
27min；
(3) step (2) filtrate being warming up to 87 DEG C, step (1) mixed-powder is added under the conditions of being 570rpm in mixing speed,
Continue to stir 22min, be cooled to 45 DEG C of addition tfe polymer chelating agents and sorbierite, continues to stir 1.2h；
(4) it is added in Manufacturing medicine extract machine after mixing step (3) gains and lauryl sodium sulfate, filling after cream processed, sterilization,
It seals to obtain the final product.
Embodiment 3
A kind of stain removing toothpaste, the raw material including following parts by weight: 25 parts of sorbierite, 4 parts of lauryl sodium sulfate, polymerization
10 parts of object iron chelating agent, 8 parts of aster, 5 parts of ardisia japonica, 3 parts of duckweed, 0.5 part of Fructus Aurantii；
The structural formula of tfe polymer chelating agent are as follows:
In formula: x 50, y 500.
A kind of preparation method of stain removing toothpaste, comprising the following steps:
(1) aster and duckweed are weighed by weight, and it is 100 μm that partial size is ground into after being freeze-dried under subzero 10 degrees Celsius
Mixed-powder；
(2) ardisia japonica and Fructus Aurantii are weighed by weight, is ground into fine powder, crosses 50 meshes, and it is 50% that 2 times of volumetric concentrations, which are added,
Ethanol solution, filter after ultrasonic extraction, obtain filtrate, ultrasonic temperature is 75 DEG C, ultrasonic power 500W, and ultrasonic time is
30min；
(3) step (2) filtrate being warming up to 90 DEG C, step (1) mixed-powder is added under the conditions of being 600rpm in mixing speed,
Continue to stir 25min, be cooled to 50 DEG C of addition tfe polymer chelating agents and sorbierite, continues to stir 1.5h；
(4) it is added in Manufacturing medicine extract machine after mixing step (3) gains and lauryl sodium sulfate, filling after cream processed, sterilization,
It seals to obtain the final product.
Embodiment 4
A kind of stain removing toothpaste, the raw material including following parts by weight: 23-27 parts of sorbierite, lauryl sodium sulfate 3-5
Part, 9-11 parts of tfe polymer chelating agent, 7-9 parts of aster, 4.5-5.5 parts of ardisia japonica, 2.5-3.5 parts of duckweed, Fructus Aurantii 0.4-0.6
Part；
The structural formula of tfe polymer chelating agent are as follows:
In formula: x 55, y 550.
A kind of preparation method of stain removing toothpaste, comprising the following steps:
(1) aster and duckweed are weighed by weight, and it is 125 μm that partial size is ground into after being freeze-dried under subzero 9 degrees Celsius
Mixed-powder；
(2) ardisia japonica and Fructus Aurantii are weighed by weight, is ground into fine powder, cross 50 meshes, 2.5 times of volumetric concentrations, which are added, is
50% ethanol solution filters after ultrasonic extraction, obtains filtrate, and ultrasonic temperature is 76 DEG C, ultrasonic power 510W, and ultrasonic time is
32min；
(3) step (2) filtrate being warming up to 92 DEG C, step (1) mixed-powder is added under the conditions of being 620rpm in mixing speed,
Continue to stir 27min, be cooled to 55 DEG C of addition tfe polymer chelating agents and sorbierite, continues to stir 1.7h；
(4) it is added in Manufacturing medicine extract machine after mixing step (3) gains and lauryl sodium sulfate, filling after cream processed, sterilization,
It seals to obtain the final product.
Embodiment 5
A kind of stain removing toothpaste, the raw material including following parts by weight: 20-30 parts of sorbierite, lauryl sodium sulfate 2-6
Part, 8-12 parts of tfe polymer chelating agent, 6-10 parts of aster, 4-6 parts of ardisia japonica, 2-4 parts of duckweed, 0.3-0.7 parts of Fructus Aurantii；
The structural formula of tfe polymer chelating agent are as follows:
In formula: x 60, y 600.
A kind of preparation method of stain removing toothpaste, comprising the following steps:
(1) aster and duckweed are weighed by weight, and it is 150 μm that partial size is ground into after being freeze-dried under subzero 8 degrees Celsius
Mixed-powder；
(2) ardisia japonica and Fructus Aurantii are weighed by weight, is ground into fine powder, crosses 50 meshes, and it is 50% that 3 times of volumetric concentrations, which are added,
Ethanol solution, filter after ultrasonic extraction, obtain filtrate, ultrasonic temperature is 77 DEG C, ultrasonic power 520W, and ultrasonic time is
35min；
(3) step (2) filtrate being warming up to 95 DEG C, step (1) mixed-powder is added under the conditions of being 650rpm in mixing speed,
Continue to stir 30min, be cooled to 60 DEG C of addition tfe polymer chelating agents and sorbierite, continues to stir 2h；
(4) it is added in Manufacturing medicine extract machine after mixing step (3) gains and lauryl sodium sulfate, filling after cream processed, sterilization,
It seals to obtain the final product.
Comparative example 1
In addition to not containing tfe polymer chelating agent in raw material, other preparation processes and embodiment 3 are consistent.
Comparative example 2
In addition to not containing aster in raw material, other preparation processes and embodiment 3 are consistent.
Comparative example 3
In addition to not containing tfe polymer chelating agent and aster in raw material, other preparation processes and embodiment 3 are consistent.
Comparative example 4
Raw material and embodiment 3 are consistent, and aster, duckweed, ardisia japonica and Fructus Aurantii are smashed it through 50 meshes when preparation, are added 2
The ethanol solution that times volumetric concentration is 50% filters after 75 DEG C of immersion 35min, and filtrate is cooled to 60 DEG C, and low whipping speed is
Tfe polymer chelating agent and sorbierite is added in 600rpm, continues that cream processed is added after stirring 1.5h and lauryl sodium sulfate mixing
Filling after cream processed in machine, sterilization is sealed to obtain the final product.
Comparative example 5
Use the stain removing toothpaste of commercially available model T300 for comparative example 5.
Experimental example 1
Stain performance test is carried out to the embodiment 1-5 and comparative example 1-5 toothpaste prepared, goes stain performance test using tooth bacterium
Spot evaluation assessment:
Experimental subjects: whole body health in order, without important whole body system disease, have 20 or more detectable teeth
Tooth；Age is in 18 one full year of life~70 one full year of life；With each 100 people (female in non-pregnancy and nursing period of suitable degree of bacterial plaque men and women
Property)；It is divided into 10 groups, each 5 people of every group of men and women is random to be grouped.
Experimental method and evaluation criterion: the toothpaste of embodiment 1-5 and comparative example 1-5 are respectively issued to every group of tester.?
It needs first to carry out scaling to subject before test, removes dental calculus, remove bacterial plaque, soft dirt with rubber polishing cup on the day of on-test, so
After begin to use product；Tester brushes teeth in the same manner using when toothpaste, respectively uses 5 days.Plaque index inspection choosing
10 fixed teeth are rowed dry facing when inspection with probe, are remembered according to the amount of bacterial plaque and thickness with the method inspection of visual examination bonding probes
Point.Every tooth four facings of inspection, i.e., close middle buccal surface, center buccal surface, remote middle buccal surface and lingual surface.Scoring criteria: the area 0=Yin Yuan
Without bacterial plaque；The facing in the area 1=Yin Yuan has thin bacterial plaque, but visual examination is invisible, if can scrape bacterial plaque with the side of probe pinpoint；2=
In gum edge or the visible moderate bacterial plaque of proximal surface；The area gingival sulcus Nei Huoyinyuan 3=and proximal surface have a large amount of soft dirts.Every scoring for tooth is four
A facing the sum of is scored divided by 4, and individual, which scores, the sum of to score for every tooth divided by by inspection tooth number.It the results are shown in Table 1.
Table 1 goes stain the performance test results
| Project | Average mark | Project | Average average mark |
| Embodiment 1 | 0.25 | Comparative example 1 | 0.44 |
| Embodiment 2 | 0.23 | Comparative example 2 | 0.35 |
| Embodiment 3 | 0.21 | Comparative example 3 | 0.66 |
| Embodiment 4 | 0.22 | Comparative example 4 | 0.29 |
| Embodiment 5 | 0.25 | Comparative example 5 | 0.45 |
Experimental example 2
Bactericidal effect experiment is carried out to toothpaste prepared by embodiment 1-5 and comparative example 1-5, the specific method is as follows: by (9-
10) × 104cfu/g bacterium solution is uniformly coated on plate, and toothpaste is equably then applied to planar surface.It cultivates together
Time 5 minutes, bacteria living quantity (unit cfu/g) on plate is measured, by the amount of survival and bacterial number phase in original bacteria liquid
Than obtaining sterilizing rate (%), test result part table 2.
2 bactericidal effect test result of table
| Project | Sterilizing rate (%) | Project | Sterilizing rate (%) |
| Embodiment 1 | 99.8 | Comparative example 1 | 95.5 |
| Embodiment 2 | 99.9 | Comparative example 2 | 96.7 |
| Embodiment 3 | 99.9 | Comparative example 3 | 90.1 |
| Embodiment 4 | 99.9 | Comparative example 4 | 99.8 |
| Embodiment 5 | 99.8 | Comparative example 5 | 91.2 |
Experimental example 3
The satisfied test of breath freshening is carried out to the tester of experimental example 1, whether is satisfied with according to user as evaluation result,
Statistics is satisfied with number and calculates satisfaction rate, and evaluation result is shown in Table 3.
The test result with fresh air of table 2
| Project | It is satisfied with number | Satisfaction rate (%) | Project | It is satisfied with number | Satisfaction rate (%) |
| Embodiment 1 | 19 | 95 | Comparative example 1 | 14 | 70 |
| Embodiment 2 | 19 | 95 | Comparative example 2 | 16 | 80 |
| Embodiment 3 | 20 | 100 | Comparative example 3 | 5 | 15 |
| Embodiment 4 | 19 | 95 | Comparative example 4 | 18 | 90 |
| Embodiment 5 | 19 | 95 | Comparative example 5 | 15 | 75 |
Case 1
Lee, male, 25 years old, Huainan, Anhui people from city, tooth jaundice had calculus dentalis, brushing teeth to be showed no using various toothpaste changes
Kind, the toothpaste provided using the embodiment of the present invention 3, sooner or later primary daily, after one month, tooth gradually bleaches, and calculus dentalis starts
It reduces, after three months, calculus dentalis disappears, teeth whiter.
Case 2
Mr. Wang, female, 30 years old, jiangsu wuxi people from city, tooth blacked, and frequent bleeding gums are brushed teeth not using various toothpaste
See improvement, the toothpaste provided using the embodiment of the present invention 3, sooner or later primary daily, after one month, tooth gradually bleaches, and gum goes out
Blood situation is reduced, and after six months, teeth whiter, bleeding gums disappear.
Case 3
Zhang, male, 33 years old, people from Beijing had obvious plaque and halitosis, is brushed teeth using various toothpaste and is showed no improvement,
The toothpaste provided using the embodiment of the present invention 3, sooner or later primary daily, after one month, plaque and halitosis situation are alleviated, and six
After a month, plaque disappears substantially, without obvious halitosis.
The preferred embodiment of the patent is described in detail above, but this patent is not limited to above-mentioned embodiment party
Formula within the knowledge of one of ordinary skill in the art can also be under the premise of not departing from this patent objective
It makes a variety of changes.
Claims (7)
1. a kind of stain removing toothpaste, which is characterized in that the raw material including following parts by weight: 20-30 parts of sorbierite, dodecyl sulphur
Sour sodium 2-6 parts, 8-12 parts of tfe polymer chelating agent, 6-10 parts of aster, 4-6 parts of ardisia japonica, 2-4 parts of duckweed, Fructus Aurantii 0.3-0.7
Part；
The structural formula of tfe polymer chelating agent are as follows:
In formula: x is the integer of 40-60, and y is the integer of 400-600.
2. stain removing toothpaste according to claim 1, which is characterized in that the raw material including following parts by weight: sorbierite 23-
27 parts, 3-5 parts of lauryl sodium sulfate, 9-11 parts of tfe polymer chelating agent, 7-9 parts of aster, 4.5-5.5 parts of ardisia japonica, duckweed
2.5-3.5 0.4-0.6 parts of part, Fructus Aurantii.
3. stain removing toothpaste according to claim 1, which is characterized in that the raw material including following parts by weight: sorbierite 25
Part, 4 parts of lauryl sodium sulfate, 10 parts of tfe polymer chelating agent, 8 parts of aster, 5 parts of ardisia japonica, 3 parts of duckweed, 0.5 part of Fructus Aurantii.
4. a kind of preparation method of stain removing toothpaste a method according to any one of claims 1-3, which comprises the following steps:
(1) aster and duckweed are weighed by weight, and the mixed-powder that partial size is 50-150 μm is ground into after freeze-drying；
(2) ardisia japonica and Fructus Aurantii are weighed by weight, is ground into fine powder, crosses 50 meshes, and it is 50% that 1-3 times of volumetric concentration, which is added,
Ethanol solution filters after ultrasonic extraction, obtains filtrate；
(3) step (2) filtrate is warming up to 85-95 DEG C, step (1) mixed-powder is added under stirring condition, continue to stir 20-
30min is cooled to 40-60 DEG C of addition tfe polymer chelating agent and sorbierite, continues to stir 1-2h；
(4) it is added in Manufacturing medicine extract machine after mixing step (3) gains and lauryl sodium sulfate, it is filling after cream processed, it sterilizes, sealing
To obtain the final product.
5. the preparation method of stain removing toothpaste as claimed in claim 4, which is characterized in that freeze-drying temperature in the step (1)
Degree is subzero 12 degrees Celsius to subzero 8 degrees Celsius, and the mixed-powder that partial size is 100 μm is obtained after crushing.
6. the preparation method of stain removing toothpaste as claimed in claim 4, which is characterized in that ultrasonic temperature is in the step (2)
73-77 DEG C, ultrasonic power 480-520W, ultrasonic time 25-35min.
7. the preparation method of stain removing toothpaste as claimed in claim 4, which is characterized in that filter step (2) in the step (3)
Liquid is warming up to 90 DEG C, and step (1) mixed-powder is added under the conditions of being 550-650rpm in mixing speed, continues to stir 25min, cooling
To 50 DEG C of addition tfe polymer chelating agents and sorbierite, continue to stir 1.5h.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811214362.5A CN109010097A (en) | 2018-10-18 | 2018-10-18 | A kind of stain removing toothpaste and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811214362.5A CN109010097A (en) | 2018-10-18 | 2018-10-18 | A kind of stain removing toothpaste and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109010097A true CN109010097A (en) | 2018-12-18 |
Family
ID=64613357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811214362.5A Withdrawn CN109010097A (en) | 2018-10-18 | 2018-10-18 | A kind of stain removing toothpaste and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109010097A (en) |
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2018
- 2018-10-18 CN CN201811214362.5A patent/CN109010097A/en not_active Withdrawn
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Application publication date: 20181218 |