CN108992511A - A kind of stomach strengthening and digestion promoting water-bindered pill and preparation method thereof - Google Patents

A kind of stomach strengthening and digestion promoting water-bindered pill and preparation method thereof Download PDF

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CN108992511A
CN108992511A CN201811255349.4A CN201811255349A CN108992511A CN 108992511 A CN108992511 A CN 108992511A CN 201811255349 A CN201811255349 A CN 201811255349A CN 108992511 A CN108992511 A CN 108992511A
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freeze
weight
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water
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赵立军
吴海林
张亚民
高志佳
赵玉才
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Qinghai Future King Gesar Pharmaceutical Co Ltd
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    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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Abstract

A kind of stomach strengthening and digestion promoting water-bindered pill and preparation method thereof, the preparation including Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, the preparation of granatum, hawthorn and pawpaw mixed serum, the preparation of radix aucklandiae and elecampane mixed slurry and the preparation of the stomach strengthening and digestion promoting water-bindered pill.Composition of raw materials includes the raw material of following parts by weight: the Calcite of 8-11 parts by weight, the Piper longum of 10-13 parts by weight and the freeze-dried mixed powder of rhododendron anthopogonoide, the radix aucklandiae of 3-5 parts by weight, the granatum of 5-7 parts by weight, the hawthorn of 5-8 parts by weight, the elecampane of 1-3 parts by weight, 3-5 parts by weight pawpaw.The stomach strengthening and digestion promoting water-bindered pill produced by the present invention is using Chinese medicines such as Calcite, fructus piperis longi, radix aucklandiae, granatum, hawthorn, elecampane, rhododendron anthopogonoide, pawpaws as raw material, water-bindered pill preparation is made after grinding, crushing, mixing, it has stomach invigorating and digestion promoting effects, eliminating cold to stop pain and other effects, do not disappear for treating weakness of the spleen and the stomach, cold solidifying food stagnation, epigastric distending pain, diet, and chronic gastritis, the illnesss such as peptic ulcer.

Description

A kind of stomach strengthening and digestion promoting water-bindered pill and preparation method thereof
Technical field
The present invention relates to a kind of stomach strengthening and digestion promoting water-bindered pills and preparation method thereof, belong to Tibetan medicine preparation technical field.
Background technique
Calcite is the mineral crystal of Sulfates mineral saltcake.It is coarse aggregate that Tibet, which produces " Calcite ", In irregular bulk, there are corner angle;In shallow sepia, have hyaloid gloss, it is translucent.Calcite function is heat-clearing and fire-reducing, benefit Key, detumescence;Primary treatment accumulated heat polydipsia, vomiting and diarrhoea, oedema, renal shutdown, bleeding from the gum, erysipelas, scald etc..
Bi is dialled, alias Bi Bo, fructus piperis longi, piper longum, climbs up by holding on to liana for Piperaceae Piper, with it is dry close mature or at Ripe fruit ear is used as medicine.Piper longum is analgesia Chinese medicine for invigorating stomach material, for treating abdominal pain caused by stomach cold, acid regurgitation, diarrhea, indigestion Deng.
Radix aucklandiae is the root of compositae plant radix aucklandiae, and cylindrical or flat round cylindricality, surface is yellowish-brown, taupe or brown Color.The cork of radix aucklandiae finished product has removed mostly, has bright longitudinal furrow and lateral root trace, sometimes visible reticular texture.Radix aucklandiae have it is strong and Special aromatic odor cures mainly promoting qi circulation and relieving pain, reinforcing spleen to promote digestion.
Granatum is the drying pericarp of Punicaceae plant pomegranate.Granatum has relieving diarrhea with astringents, stops blooding, expelling parasite and other effects, For treating the illnesss such as chronic diarrhea, protracted dysentery, hematochezia, rectal prolapse, metrorrhagia and metrostaxis, abdominal pain due to enterositosis.
Hawthorn also known as hawthorn, large-fruited Chinese hawthorn, rosaceae hawthorn, deciduous tree.Hawthorn is stone fruit, and caryoplasm is hard, Pulp is thin, and taste is slightly sour puckery.It can be used as medicine after Fructus Crataegi is drying, be the distinctive dual-purpose of drug and fruit tree species of China, there is reducing blood lipid, blood The effects of pressure, heart tonifying, arrhythmia, while being also the good medicine of spleen benefiting and stimulating the appetite, relieving dyspepsia, phlegm reduction of blood circulation promoting, full to chest diaphragm spleen, The diseases such as hernia, blood stasis, amenorrhoea have good curative effect.
Elecampane is the dry root of compositae plant elecampane or Tibet inula root;Autumn excavation, removes silt, drying can obtain. Elecampane has the effect of strengthening the spleen and stomach, promoting the flow of qi and relieving stagnancy, analgesic tocolysis, for treating chest side of body, abdominal distention, vomiting dysentery, chest The side of body dampens, feel a pain in the chest when breathing have a pain, the illnesss such as threatened abortion.
Rhododendron anthopogonoide is evergreen shrubs, and leaf and flower are rich in volatile oil, is good fragrance and Chinese medicine, has eliminating the phlegm, stops Cough is relievingd asthma and other effects.
Pawpaw is rosaceous plant, is shrub or dungarunga.Pawpaw fruit puckery can be used as medicine, and have and relieve the effect of alcohol, remove phlegm, is suitable Gas, stop dysentery and other effects.
Summary of the invention
The purpose of the present invention is to provide a kind of stomach strengthening and digestion promoting water-bindered pills and preparation method thereof.
In order to achieve the above objects and other related objects, present invention provide the technical scheme that a kind of stomach strengthening and digestion promoting water-bindered pill, Composition of raw materials includes the raw material of following parts by weight: the Calcite of 8-11 parts by weight, the Piper longum of 10-13 parts by weight and rhododendron anthopogonoide Freeze-dried mixed powder, the radix aucklandiae of 3-5 parts by weight, the granatum of 5-7 parts by weight, the hawthorn of 5-8 parts by weight, 1-3 parts by weight building Fragrant, 3-5 parts by weight pawpaws.
Preferred technical solution are as follows: the Calcite, radix aucklandiae, granatum, hawthorn, elecampane and pawpaw are drying Product.
In order to achieve the above objects and other related objects, present invention provide the technical scheme that a kind of stomach strengthening and digestion promoting water-bindered pill Preparation method, composition of raw materials use claims 1 or 2 composition of raw materials, preparation method include Piper longum and rhododendron anthopogonoide mixing The preparation and stomach invigorating of the preparation of freeze-dried powder, the preparation of granatum, hawthorn and pawpaw mixed serum, radix aucklandiae and elecampane mixed slurry Help digestion the preparation of the water-bindered pill;
The preparation of the Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide includes: by the fresh leaf of the mature fruit cluster of Piper longum, rhododendron anthopogonoide Piece cleans and drains surface moisture;Then Piper longum fruit ear, rhododendron anthopogonoide blade are freeze-dried, until water content is 5-8% When terminate to be freeze-dried, be then crushed under the conditions of -80 ~ -60 DEG C of temperature fineness be 170-200 mesh, obtain Piper longum and strong perfume (or spice) The freeze-dried mixed powder of cuckoo, it is spare;
The preparation of the granatum, hawthorn and pawpaw mixed serum includes: to mix granatum, hawthorn and pawpaw, is broken into 10- Then the hybrid particles of 12 mesh carry out the hybrid particles after 2-3 freeze thawing treatment obtains freeze thawing treatment to hybrid particles, then will Hybrid particles after freeze thawing treatment are mixed with water 1:1-2 in mass ratio, and the fineness for being ground to solid content is 170-200 mesh, are obtained Granatum, hawthorn and pawpaw mixed serum;
The preparation of the radix aucklandiae and elecampane mixed slurry includes: to mix radix aucklandiae and elecampane, and it is uniform to be broken into 10-12 purpose Then particle impregnates 3-5h with 5-30 DEG C of water;Radix aucklandiae after immersion is taken out with elecampane hybrid particles, it is quick-fried to be placed in steam Steam explosion treatment is carried out in broken equipment;Then the radix aucklandiae after Steam explosion treatment is ground to solid with elecampane hybrid particles The fineness of object is 170-200 mesh, obtains radix aucklandiae and elecampane mixed slurry, spare;
The preparation of the stomach strengthening and digestion promoting water-bindered pill includes: by Calcite, Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, granatum, mountain Short, bristly hair or beard and pawpaw mixed serum are uniformly mixed with radix aucklandiae and elecampane mixed slurry, and the water-bindered pill is made using medicinal machine for making water-bindered pills, then adopts With 50-55 DEG C of heated-air drying to water content 5-8%, stomach strengthening and digestion promoting water-bindered pill product is obtained.
Preferred technical solution are as follows: the temperature of the freeze-drying is -50 ~ -40 DEG C, the vacuum gauge pressure of freeze drier For -0.09 ~ -0.10Mpa, lower freeze-drying water content processed is 5-8%.Then the material after freeze-drying ultralow temperature crushing is placed in set In standby, under the conditions of -80 ~ -60 DEG C of temperature, being crushed to fineness is 170-200 mesh, obtains Piper longum and rhododendron anthopogonoide is freeze-dried mixed Powder, it is spare.
Preferred technical solution are as follows: the technological parameter of the Steam explosion treatment are as follows: ratio of water to material 1:4-8, dimension pressure time 90- 180s, steam pressure 1.8-2.0MPa.
Preferred technical solution are as follows: the freeze thawing treatment is that hybrid particles are placed in 2-3min in liquid nitrogen, and taking-up is placed in 2-3min in 87-93 DEG C of hot wind environment.
Since above-mentioned technical proposal is used, the present invention has the advantage, that compared with prior art
The stomach strengthening and digestion promoting water-bindered pill produced by the present invention with Calcite, fructus piperis longi, radix aucklandiae, granatum, hawthorn, elecampane, rhododendron anthopogonoide, The Chinese medicines such as pawpaw are raw material, and water-bindered pill preparation is made after grinding, crushing, mixing, are had stomach invigorating and digestion promoting effects, the function such as eliminating cold to stop pain Effect, for treating, weakness of the spleen and the stomach, cold solidifying food stagnation, epigastric distending pain, diet does not disappear and chronic gastritis, the illnesss such as peptic ulcer.
Specific embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this implementation Content disclosed by example is understood other advantages and efficacy of the present invention easily.
The purpose of term used herein, which is only that, illustrates particular embodiment, it is not intended to be limited to the present invention.It removes Non- context is explicitly shown, otherwise singular " one " used herein, "one" also include plural form.
When illustrating preferred embodiment, it is potentially based on clear purpose and uses special term;However, this specification institute Revealer is not intended to be limited in the selected special term;And it is to be understood that each particular element includes having Identical function, all equivalence techniques for operating in a similar manner and reaching similar effects.
A kind of embodiment one: stomach strengthening and digestion promoting water-bindered pill and preparation method thereof
A kind of stomach strengthening and digestion promoting water-bindered pill and preparation method thereof, which is characterized in that include the following steps.
(1) the freeze-dried mixed powder of Piper longum, rhododendron anthopogonoide is prepared
The mature fruit cluster of Piper longum, the fresh blade of rhododendron anthopogonoide are harvested, cleans and drains surface moisture.By Piper longum fruit ear, strong perfume (or spice) Cuckoo blade 1:1 in mass ratio mixing, is placed in freeze drying equipment, cold at -45 DEG C of temperature, vacuum gauge pressure -0.095MPa It is 6.5% that dry water content processed, which is lyophilized,.Then the material after freeze-drying is placed in ultralow temperature disintegrating apparatus, in -70 DEG C of temperature conditions Under, being crushed to fineness is 180 mesh, obtains Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, spare.
(2) raw material preparation
By mass, prepare 10 parts of Calcites, 12 parts of Piper longums and the freeze-dried mixed powder of rhododendron anthopogonoide, 4 parts of radix aucklandiaes, 6 portions of pomegranates Skin, 6 portions of hawthorn, 2 parts of elecampanes, 4 portions of pawpaws.
The Calcite, radix aucklandiae, granatum, hawthorn, elecampane, pawpaw are dried product.
(3) granatum, hawthorn, pawpaw mixed slurry are prepared
The granatum got ready, hawthorn, pawpaw are mixed, the single-size of 11 mesh is broken into;It is fast quick-frozen by hybrid particles progress 2 times Melt processing, i.e., hybrid particles are placed in 2.5min in liquid nitrogen, takes out be placed in 2.5min in 90 DEG C of hot wind environment rapidly;Then again Secondary be first placed in liquid nitrogen and hot wind environment is handled, so circulation 2 times.
Hybrid particles after freeze thawing treatment are mixed with distilled water 1:1 in mass ratio, are ground to stainless-steel grinding equipment Fineness is 180 mesh, obtains granatum, hawthorn, pawpaw mixed serum, spare.
(4) radix aucklandiae, elecampane mixed slurry are prepared
The radix aucklandiae got ready, elecampane are mixed, the single-size of 11 mesh is broken into, then using enough distilled water in 18 DEG C of temperature Degree is lower to impregnate 4h;Radix aucklandiae, elecampane hybrid particles after immersion are taken out, are placed in steam blasting equipment, using ratio of water to material The parameter of 1:6, dimension pressure time 135s, steam pressure 1.65MPa, carry out Steam explosion treatment.
By radix aucklandiae, the elecampane hybrid particles after steam blasting, being ground to fineness with stainless-steel grinding equipment is 180 mesh, Radix aucklandiae, elecampane mixed slurry are obtained, it is spare.
(5) water-bindered pill preparation is prepared
The Calcite that will be got ready, Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, granatum, hawthorn, pawpaw mixed slurry, radix aucklandiae, Elecampane mixed slurry is uniformly mixed, the water-bindered pill is made using medicinal machine for making water-bindered pills, then using 52 DEG C of heated-air dryings to water content 6.5%, obtain stomach strengthening and digestion promoting water-bindered pill formulation products.
Gastroenterology dept. 2015.03~2018.03 accept for medical treatment indigestion patient (weakness of the spleen and the stomach, cold solidifying food stagnation, epigastric distending pain, Diet does not disappear and chronic gastritis, the illnesss such as peptic ulcer) 80 progress clinical observations of middle selection, patient is divided equally into cost Stomach strengthening and digestion promoting water-bindered pill medication group (40) made from embodiment, existing digestion-promoting stomachic medication group (40).Men and women respectively has 22 With 18, the age 34 to 58 years old.Exclude organic disease patient, deformation patients, clouding of consciousness patient, drug allergy patient and Mismatch Medication study patient.It is aided with polyzyme tablets and vitamin B1 medication treatment during medication, treats 30 days by a definite date.This implementation Stomach strengthening and digestion promoting water-bindered pill medication group curative effect made from example, which reaches, 20, effectively there is 10, and fine has 7, and invalid has 3 Example, total effects rate is 92.5%(37/40).Existing digestion-promoting stomachic medication group it is effective have 15, effectively have 8, it is fine There are 5, invalid there are 12, and total effects rate is 70%(28/40).
A kind of embodiment two: stomach strengthening and digestion promoting water-bindered pill and preparation method thereof
A kind of stomach strengthening and digestion promoting water-bindered pill, composition of raw materials include the raw material of following parts by weight: the Calcite of 8 parts by weight, 10 parts by weight Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, the radix aucklandiae of 3 parts by weight, the granatum of 5 parts by weight, the hawthorn of 5 parts by weight, 1 weight Part elecampane, 3 parts by weight pawpaw.
The Calcite, radix aucklandiae, granatum, hawthorn, elecampane and pawpaw are dried product.
Preparation method includes the preparation of Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, granatum, hawthorn and pawpaw mixed serum Preparation, the preparation of radix aucklandiae and elecampane mixed slurry and the preparation of the stomach strengthening and digestion promoting water-bindered pill;
The preparation of the Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide includes: by the fresh leaf of the mature fruit cluster of Piper longum, rhododendron anthopogonoide Piece cleans and drains surface moisture;Then Piper longum fruit ear, rhododendron anthopogonoide blade are freeze-dried, until when water content is 5% Terminate freeze-drying, it is 170 mesh that fineness is then crushed under the conditions of -80 DEG C of temperature, obtains Piper longum and rhododendron anthopogonoide mixing is frozen Dry powder, it is spare;
The preparation of the granatum, hawthorn and pawpaw mixed serum includes: to mix granatum, hawthorn and pawpaw, is broken into 10 Then purpose hybrid particles carry out the hybrid particles after 2 freeze thawing treatments obtain freeze thawing treatment to hybrid particles, then by freeze thawing Treated, and hybrid particles are mixed with water 1:1.5 in mass ratio, and the fineness for being ground to solid content is 170 mesh, obtain granatum, mountain Short, bristly hair or beard and pawpaw mixed serum;
The preparation of the radix aucklandiae and elecampane mixed slurry includes: to mix radix aucklandiae and elecampane, is broken into 10 purposes uniform Then grain impregnates 3h with 5 DEG C of water;Radix aucklandiae after immersion is taken out with elecampane hybrid particles, is placed in steam blasting equipment Middle carry out Steam explosion treatment;Then the radix aucklandiae after Steam explosion treatment is ground to the thin of solid content with elecampane hybrid particles Degree is 170 mesh, obtains radix aucklandiae and elecampane mixed slurry, spare;
The preparation of the stomach strengthening and digestion promoting water-bindered pill includes: by Calcite, Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, granatum, mountain Short, bristly hair or beard and pawpaw mixed serum are uniformly mixed with radix aucklandiae and elecampane mixed slurry, and the water-bindered pill is made using medicinal machine for making water-bindered pills, then adopts With 50 DEG C of heated-air dryings to water content 5%, stomach strengthening and digestion promoting water-bindered pill product is obtained.
Preferred embodiment are as follows: the temperature of the freeze-drying is -50 DEG C, the vacuum gauge pressure of freeze drier is - 0.09Mpa, lower freeze-drying water content processed is 5%.Then the material after freeze-drying is placed in ultralow temperature disintegrating apparatus, at -80 DEG C Under the conditions of temperature, being crushed to fineness is 170 mesh, obtains Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, spare.
Preferred embodiment are as follows: the technological parameter of the Steam explosion treatment are as follows: ratio of water to material 1:4, dimension pressure time 90s, Steam pressure 1.8MPa.
Preferred embodiment are as follows: the freeze thawing treatment is that hybrid particles are placed in 2min in liquid nitrogen, and taking-up is placed in 87 DEG C hot wind environment in 2min.
A kind of embodiment three: stomach strengthening and digestion promoting water-bindered pill and preparation method thereof
A kind of stomach strengthening and digestion promoting water-bindered pill, composition of raw materials include the raw material of following parts by weight: the Calcite of 11 parts by weight, 13 parts by weight Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, the radix aucklandiae of 5 parts by weight, the granatum of 7 parts by weight, the hawthorn of 8 parts by weight, 3 weight Part elecampane, 5 parts by weight pawpaw.
The Calcite, radix aucklandiae, granatum, hawthorn, elecampane and pawpaw are dried product.
Preparation method includes the preparation of Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, granatum, hawthorn and pawpaw mixed serum Preparation, the preparation of radix aucklandiae and elecampane mixed slurry and the preparation of the stomach strengthening and digestion promoting water-bindered pill;
The preparation of the Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide includes: by the fresh leaf of the mature fruit cluster of Piper longum, rhododendron anthopogonoide Piece cleans and drains surface moisture;Then Piper longum fruit ear, rhododendron anthopogonoide blade are freeze-dried, until when water content is 8% Terminate freeze-drying, it is 200 mesh that fineness is then crushed under the conditions of -60 DEG C of temperature, obtains Piper longum and rhododendron anthopogonoide mixing is frozen Dry powder, it is spare;
The preparation of the granatum, hawthorn and pawpaw mixed serum includes: to mix granatum, hawthorn and pawpaw, is broken into 12 Then purpose hybrid particles carry out the hybrid particles after 3 freeze thawing treatments obtain freeze thawing treatment to hybrid particles, then by freeze thawing Treated, and hybrid particles are mixed with water 1:2 in mass ratio, and the fineness for being ground to solid content is 200 mesh, obtain granatum, hawthorn With pawpaw mixed serum;
The preparation of the radix aucklandiae and elecampane mixed slurry includes: to mix radix aucklandiae and elecampane, is broken into 12 purposes uniform Then grain impregnates 5h with 30 DEG C of water;Radix aucklandiae after immersion is taken out with elecampane hybrid particles, is placed in steam blasting equipment Middle carry out Steam explosion treatment;Then the radix aucklandiae after Steam explosion treatment is ground to the thin of solid content with elecampane hybrid particles Degree is 200 mesh, obtains radix aucklandiae and elecampane mixed slurry, spare;
The preparation of the stomach strengthening and digestion promoting water-bindered pill includes: by Calcite, Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, granatum, mountain Short, bristly hair or beard and pawpaw mixed serum are uniformly mixed with radix aucklandiae and elecampane mixed slurry, and the water-bindered pill is made using medicinal machine for making water-bindered pills, then adopts With 55 DEG C of heated-air dryings to water content 8%, stomach strengthening and digestion promoting water-bindered pill product is obtained.
Preferred embodiment are as follows: the temperature of the freeze-drying is -40 DEG C, the vacuum gauge pressure of freeze drier is - 0.10Mpa, lower freeze-drying water content processed is 8%.Then the material after freeze-drying is placed in ultralow temperature disintegrating apparatus, at -60 DEG C Under the conditions of temperature, being crushed to fineness is 200 mesh, obtains Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, spare.
Preferred embodiment are as follows: the technological parameter of the Steam explosion treatment are as follows: ratio of water to material 1:8, dimension pressure time 180s, Steam pressure 2.0MPa.
Preferred embodiment are as follows: the freeze thawing treatment is that hybrid particles are placed in 3min in liquid nitrogen, and taking-up is placed in 93 DEG C hot wind environment in 3min.
As described above is only to be not intended to tool to explain the preferred embodiments of the invention to do any shape to the present invention Limitation in formula should all wrap therefore all have any modification or change for making the related present invention under identical spirit It includes in the scope that the invention is intended to protect.

Claims (6)

1. a kind of stomach strengthening and digestion promoting water-bindered pill, it is characterised in that: composition of raw materials includes the raw material of following parts by weight: the south of 8-11 parts by weight Gypsum rubrum, the Piper longum of 10-13 parts by weight and the freeze-dried mixed powder of rhododendron anthopogonoide, the radix aucklandiae of 3-5 parts by weight, 5-7 parts by weight pomegranate Skin, the hawthorn of 5-8 parts by weight, the elecampane of 1-3 parts by weight, 3-5 parts by weight pawpaw.
2. the stomach strengthening and digestion promoting water-bindered pill according to claim 1, it is characterised in that: the Calcite, radix aucklandiae, granatum, mountain Short, bristly hair or beard, elecampane and pawpaw are dried product.
3. a kind of preparation method of the stomach strengthening and digestion promoting water-bindered pill, it is characterised in that: composition of raw materials is matched using the raw material of claims 1 or 2 Side, preparation method include the preparation of Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, granatum, hawthorn and pawpaw mixed serum system It is standby, the preparation of radix aucklandiae and elecampane mixed slurry and the preparation of the stomach strengthening and digestion promoting water-bindered pill;
The preparation of the Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide includes: by the fresh leaf of the mature fruit cluster of Piper longum, rhododendron anthopogonoide Piece cleans and drains surface moisture;Then Piper longum fruit ear, rhododendron anthopogonoide blade are freeze-dried, until water content is 5-8% When terminate to be freeze-dried, be then crushed under the conditions of -80 ~ -60 DEG C of temperature fineness be 170-200 mesh, obtain Piper longum and strong perfume (or spice) The freeze-dried mixed powder of cuckoo, it is spare;
The preparation of the granatum, hawthorn and pawpaw mixed serum includes: to mix granatum, hawthorn and pawpaw, is broken into 10- Then the hybrid particles of 12 mesh carry out the hybrid particles after 2-3 freeze thawing treatment obtains freeze thawing treatment to hybrid particles, then will Hybrid particles after freeze thawing treatment are mixed with water 1:1-2 in mass ratio, and the fineness for being ground to solid content is 170-200 mesh, are obtained Granatum, hawthorn and pawpaw mixed serum;
The preparation of the radix aucklandiae and elecampane mixed slurry includes: to mix radix aucklandiae and elecampane, and it is uniform to be broken into 10-12 purpose Then particle impregnates 3-5h with 5-30 DEG C of water;Radix aucklandiae after immersion is taken out with elecampane hybrid particles, it is quick-fried to be placed in steam Steam explosion treatment is carried out in broken equipment;Then the radix aucklandiae after Steam explosion treatment is ground to solid with elecampane hybrid particles The fineness of object is 170-200 mesh, obtains radix aucklandiae and elecampane mixed slurry, spare;
The preparation of the stomach strengthening and digestion promoting water-bindered pill includes: by Calcite, Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, granatum, mountain Short, bristly hair or beard and pawpaw mixed serum are uniformly mixed with radix aucklandiae and elecampane mixed slurry, and the water-bindered pill is made using medicinal machine for making water-bindered pills, then adopts With 50-55 DEG C of heated-air drying to water content 5-8%, stomach strengthening and digestion promoting water-bindered pill product is obtained.
4. the preparation method of the stomach strengthening and digestion promoting water-bindered pill according to claim 3, it is characterised in that: the temperature of the freeze-drying It is -50 ~ -40 DEG C, the vacuum gauge pressure of freeze drier is -0.09 ~ -0.10Mpa, and lower freeze-drying water content processed is 5-8%, so The material after freeze-drying is placed in ultralow temperature disintegrating apparatus afterwards, under the conditions of -80 ~ -60 DEG C of temperature, being crushed to fineness is 170- 200 mesh obtain Piper longum and the freeze-dried mixed powder of rhododendron anthopogonoide, spare.
5. the preparation method of the stomach strengthening and digestion promoting water-bindered pill according to claim 3, it is characterised in that: the Steam explosion treatment Technological parameter are as follows: ratio of water to material 1:4-8, dimension pressure time 90-180s, steam pressure 1.8-2.0MPa.
6. the preparation method of the stomach strengthening and digestion promoting water-bindered pill according to claim 3, it is characterised in that: the freeze thawing treatment is will to mix It closes particle and is placed in 2-3min in liquid nitrogen, taking-up is placed in 2-3min in 87-93 DEG C of hot wind environment.
CN201811255349.4A 2018-10-26 2018-10-26 A kind of stomach strengthening and digestion promoting water-bindered pill and preparation method thereof Pending CN108992511A (en)

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Application publication date: 20181214