CN109224018A - A kind of perfume chrysanthemum promoting blood circulation water-bindered pill and preparation method thereof - Google Patents

A kind of perfume chrysanthemum promoting blood circulation water-bindered pill and preparation method thereof Download PDF

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CN109224018A
CN109224018A CN201811264572.5A CN201811264572A CN109224018A CN 109224018 A CN109224018 A CN 109224018A CN 201811264572 A CN201811264572 A CN 201811264572A CN 109224018 A CN109224018 A CN 109224018A
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weight
parts
preparation
blood circulation
chrysanthemum
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赵立军
吴海林
张亚民
高志佳
赵玉才
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Qinghai Future King Gesar Pharmaceutical Co Ltd
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Qinghai Future King Gesar Pharmaceutical Co Ltd
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Abstract

A kind of perfume chrysanthemum promoting blood circulation water-bindered pill and preparation method thereof, composition of raw materials includes the raw material of following parts by weight: the agalloch eaglewood of 5-7 parts by weight, the nutmeg of 3-5 parts by weight, the west szechwan pyrethrum of 3-5 parts by weight, the cloves of 3-5 parts by weight, the fructus choerospondiatis of 2-4 parts by weight, the BAIYUNXIANG of 4-6 parts by weight, the radix aucklandiae of 3-5 parts by weight, the kaempferia galanga of 3-5 parts by weight, the pearl of 3-5 parts by weight, 0.8-1.2 parts by weight assistant too, the Semen Strychni (processed) of 0.8-1.2 parts by weight.The perfume chrysanthemum promoting blood circulation water-bindered pill produced by the present invention using agalloch eaglewood, nutmeg, west szechwan pyrethrum, cloves, fructus choerospondiatis, BAIYUNXIANG, radix aucklandiae, kaempferia galanga, pearl, assistant too, the Chinese medicines such as Semen Strychni (processed) is raw materials, water-bindered pill preparation is made after grinding, crushing, mixing, with the promoting flow of qi and blood circulation, the turbid analgesic of change and other effects, for treating the illnesss such as coronary disease and angina pectoris caused by qi depression to blood stasis, wet turbid resistance network.

Description

A kind of perfume chrysanthemum promoting blood circulation water-bindered pill and preparation method thereof
Technical field
The present invention relates to a kind of fragrant chrysanthemum promoting blood circulation water-bindered pills and preparation method thereof, belong to Tibetan medicine preparation technical field.
Background technique
Agalloch eaglewood is the timber that Isolated From Thymelaeaceae Species suspension culture of Aquilaria sinensis contains resin.Agalloch eaglewood has promoting qi circulation and relieving pain, warming middle energizer to arrest vomiting, gas of receiving flat Asthma and other effects is usually used in the illnesss such as the swollen bored pain of chest and abdomen, gastrofrigid vomiting hiccup, kidney deficiency circulation of vital energy in the wrong direction asthma urgency.
Nutmeg is aiphyllium plant, and kernel can be used as medicine, and has the puckery intestines of middle benefit gas, promoting the circulation of qi helps digestion and other effects, for controlling It treats void and rushes down the illnesss such as cold dysentery, coldness and pain in the epigastrium, vomiting.
West szechwan pyrethrum is composite family Chrysanthemum herbaceos perennial, and whole plant can all be used as medicine, and has promoting blood circulation, clearing damp, disappears Inflammation analgesic and other effects, for treating the illnesss such as traumatic injury, damp and hot.
Cloves is the bud dried product that the tropical plants of Myrtaceae Syzygium do not bloom, main in oil containing volatile oil Contain the ingredients such as cloves oleic acid, acetyl cloves oleic acid and the positive heptanone of cloves alkene, Methylpentanone, methyl, vanillin, there is suppression Bacterium, anthelmintic action can treat the diseases such as stomach trouble, abdominal pain, vomiting, neuralgia, toothache.
Fructus choerospondiatis is the dry mature fruit of Anacardiaceae plant Spondias axillaris, and there is the promoting flow of qi and blood circulation, nourishing heart, tranquilizing the mind, anti-cardiac muscle to lack The effects of blood, protection heart function, for treating qi depression to blood stasis, thoracic obstruction is had a pain, shortness of breath and palpitation, the illnesss such as confused and worried.
Rue is the wooden herbaceos perennial of Rutaceae rue category basal part of stem.Stem, branch, the leaf of rue can be employed as medicine Material uses, and has clearing heat and detoxicating, cool blood dissipates the stasis of blood and other effects, the illnesss such as treatment cold, fever, acute toothache, headache, bruises and sprains.
Radix aucklandiae is the root of compositae plant radix aucklandiae, and cylindrical or flat round cylindricality, surface is yellowish-brown, taupe or brown Color.The cork of radix aucklandiae finished product has removed mostly, has bright longitudinal furrow and lateral root trace, sometimes visible reticular texture.Radix aucklandiae have it is strong and Special aromatic odor cures mainly promoting qi circulation and relieving pain, reinforcing spleen to promote digestion.
Kaempferia galanga is the perennial short herbaceous plant of Zingiber Kaempferia, and rhizome is blocky, and single raw or several pieces of connections have aroma Taste.The rhizome of kaempferia galanga can be used as medicinal material use, has cold dispelling, dries, warm taste, wards off bad odor and other effects.
Pearl be Pteriidae animal pearl shell, Pinctada martensii or Unionidae animal hydriopsis cumingii, cristaria plicata, dorsal horn without Formed in the shell-fishes pearl sac such as tooth freshwater mussel without nucleus pearl, there is tranquilizing mind, yin-nourishing to relieve dizziness, high fever, infantile convulsions, epilepsy, etc., heat-clearing pendant phlegm, go screen improving eyesight, Taking poison and growing muscle due and other effects is solved, palpitation with fear, palpitation, epilepsy, infantile convulsion is twitched, dysphoria with smothery sensation is quenched one's thirst, sore throat aphthae in children, mesh raw ocular, sore for treating Ulcer such as does not close up at the illnesss long.
Assistant is the most valuable too in Tibetan medicine, is that successive dynasties name Tibetan medicine is obtained and carrying out special processing processing to hypertoxic mercury The preparation with peculiar curative effect, be the female parent of Tibetan medicine, be considered as the most valuable treasure in Tibetan medicine by the snowy region people, referred to as " many medicines it King " is commonly used to cooperation common drug and increases curative effect.
Vomiting nut is Loganiaceae Logania arbor, and seed is extremely toxic, and it is a variety of to mainly contain strychnia and brucine etc. Alkaloid.It is used as medicine after the seed of vomiting nut is processed (Semen Strychni (processed)) in Chinese medicine, there is cold in nature, bitter activating collaterals and eliminating stagnation, detumescence to stop The benefits of pain, is usually used in stomachic tonic use.
Summary of the invention
The purpose of the present invention is to provide a kind of fragrant chrysanthemum promoting blood circulation water-bindered pills and preparation method thereof.
In order to achieve the above objects and other related objects, the water-bindered pill present invention provide the technical scheme that a kind of perfume chrysanthemum is invigorated blood circulation, Composition of raw materials includes the raw material of following parts by weight: the agalloch eaglewood of 5-7 parts by weight, the nutmeg of 3-5 parts by weight, 3-5 parts by weight river Western little Huang chrysanthemum, the cloves of 3-5 parts by weight, the fructus choerospondiatis of 2-4 parts by weight, the BAIYUNXIANG of 4-6 parts by weight, the radix aucklandiae of 3-5 parts by weight, 3- The kaempferia galanga of 5 parts by weight, the pearl of 3-5 parts by weight, 0.8-1.2 parts by weight assistant too, the Semen Strychni (processed) of 0.8-1.2 parts by weight.
Preferred technical solution are as follows: the agalloch eaglewood, nutmeg, west szechwan pyrethrum, cloves, fructus choerospondiatis, BAIYUNXIANG, radix aucklandiae, mountain A kind of apple, pearl, assistant too, Semen Strychni (processed) be dried product.
In order to achieve the above objects and other related objects, the water-bindered pill present invention provide the technical scheme that a kind of perfume chrysanthemum is invigorated blood circulation Preparation method, composition of raw materials use claims 1 or 2 composition of raw materials, preparation method include the first mixing fine powders preparation, The preparations of second mixing fine powders, the preparation of mixed serum, the preparation of the preparation of Semen Strychni (processed) detoxification fine powder and the fragrant chrysanthemum promoting blood circulation water-bindered pill;
The preparation of first mixing fine powders includes: the agalloch eaglewood that will be got ready, cloves, radix aucklandiae and kaempferia galanga mixing, is broken into 10-12 mesh Particle;Broken particle is placed in liquid nitrogen pulverizer, being crushed to fineness is 170-200 mesh, the first mixing fine powders are obtained, It is spare;
The preparation of second mixing fine powders includes: that the pearl that will be got ready and Zuo Tai are mixed to get mixed material, is placed in stainless steel In ball-grinding machine, nitrogen is filled with after pumping the air in the ball grinder of stainless steel ball-milling equipment;Under nitrogen protection, by mixture Abrasive lapping to fineness is that 170-200 mesh obtains the second mixing fine powders, spare;
The preparation of the mixed serum includes: the nutmeg that will be got ready, west szechwan pyrethrum, fructus choerospondiatis and rue mixing, is broken into 10- Then hybrid particles are carried out 2-3 freeze thawing treatment by the hybrid particles of 12 mesh, after treatment is by the mixing after freeze thawing treatment Grain is mixed with distilled water 1:1-2 in mass ratio, is placed in stainless-steel grinding equipment, and being ground to fineness is 170-200 mesh;It will grinding Material afterwards, which is placed in ultrasonic equipment, handles 20-30min, then collects and obtains mixed serum;
The preparation of the Semen Strychni (processed) detoxification fine powder includes: that 5-30 DEG C of Semen Strychni (processed) of water is impregnated 30-60min, then right Semen Strychni (processed) after immersion carries out Steam explosion treatment, and the Semen Strychni (processed) after Steam explosion treatment is then placed in liquid nitrogen pulverizer In be crushed to fineness be 170-200 mesh, obtain vomiting nut detoxification fine powder;
The preparation of the perfume chrysanthemum promoting blood circulation water-bindered pill includes: by the first mixing fine powders, the second mixing fine powders, mixed serum and Semen Strychni (processed) Detoxification fine powder is uniformly mixed, and the water-bindered pill is made using medicinal machine for making water-bindered pills, then using 50-55 DEG C of heated-air drying to water content 5-8%, Obtain fragrant chrysanthemum promoting blood circulation water-bindered pill product.
Preferred technical solution are as follows: the technological parameter of the Steam explosion treatment are as follows: ratio of water to material 1:5-6, dimension pressure time 90- 180s, steam pressure 1.5-1.8Mpa.
Preferred technical solution are as follows: the frequency of the ultrasonic equipment is 25-35KHz, power density 0.4-0.5W/ cm2
Preferred technical solution are as follows: the freeze thawing treatment is that hybrid particles are placed in 2-3min in liquid nitrogen, and taking-up is placed in 2-3min in 87-93 DEG C of hot wind environment.
Since above-mentioned technical proposal is used, the present invention has the advantage, that compared with prior art
The perfume chrysanthemum promoting blood circulation water-bindered pill produced by the present invention is with agalloch eaglewood, nutmeg, west szechwan pyrethrum, cloves, fructus choerospondiatis, BAIYUNXIANG, radix aucklandiae, mountain A kind of apple, pearl, assistant too, the Chinese medicines such as Semen Strychni (processed) be raw material, water-bindered pill preparation is made after grinding, crushing, mixing, there is promoting the circulation of qi Invigorate blood circulation, change turbid analgesic and other effects, for treating the illnesss such as coronary disease and angina pectoris caused by qi depression to blood stasis, wet turbid resistance network.
Specific embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this implementation Content disclosed by example is understood other advantages and efficacy of the present invention easily.
The purpose of term used herein, which is only that, illustrates particular embodiment, it is not intended to be limited to the present invention.It removes Non- context is explicitly shown, otherwise singular " one " used herein, "one" also include plural form.
When illustrating preferred embodiment, it is potentially based on clear purpose and uses special term;However, this specification institute Revealer is not intended to be limited in the selected special term;And it is to be understood that each particular element includes having Identical function, all equivalence techniques for operating in a similar manner and reaching similar effects.
A kind of embodiment one: perfume chrysanthemum promoting blood circulation water-bindered pill and preparation method thereof
A kind of perfume chrysanthemum promoting blood circulation water-bindered pill and preparation method thereof, which is characterized in that include the following steps.
(1) raw material preparation
By mass, prepare the agalloch eaglewood of 6 parts by weight, the nutmeg of 4 parts by weight, the west szechwan pyrethrum of 4 parts by weight, 4 parts by weight Cloves, the fructus choerospondiatis of 3 parts by weight, the BAIYUNXIANG of 5 parts by weight, the radix aucklandiae of 4 parts by weight, the kaempferia galanga of 4 parts by weight, 4 parts by weight treasure Pearl, 1 parts by weight assistant too, the Semen Strychni (processed) of 1 parts by weight.
The agalloch eaglewood, nutmeg, west szechwan pyrethrum, cloves, fructus choerospondiatis, BAIYUNXIANG, radix aucklandiae, kaempferia galanga, pearl, assistant too, system Vomiting nut is dried product
(2) agalloch eaglewood, cloves, radix aucklandiae, kaempferia galanga mixing fine powders are prepared
The agalloch eaglewood got ready, cloves, radix aucklandiae, kaempferia galanga are mixed, the single-size of 11 mesh is broken into;Broken material is placed in liquid In nitrogen pulverizer, by crushing material to fineness it is 180 mesh while spraying liquid nitrogen, it is mixed obtains agalloch eaglewood, cloves, radix aucklandiae, kaempferia galanga Fine powder is closed, it is spare.
(3) nutmeg, west szechwan pyrethrum, fructus choerospondiatis, rue mixed serum are prepared
The cardamom got ready, west szechwan pyrethrum, fructus choerospondiatis, rue are mixed, the hybrid particles of 11 mesh are broken into;Hybrid particles are carried out 2 fast freeze-thaw processing, i.e., be placed in 2.5min in liquid nitrogen for hybrid particles, take out be placed in 90 DEG C of hot wind environment rapidly 2.5min;Then it is first placed in liquid nitrogen and hot wind environment and handles again, so circulation 2 times.
Multigelation treated hybrid particles are mixed with distilled water 1:1.5 in mass ratio, stainless-steel grinding is placed in and sets In standby, being ground to fineness is 180 mesh;Material after grinding is placed in ultrasonic equipment and handles 25min, ultrasonic frequency is 30KHz, power density 0.45W/cm2;Then, nutmeg, west szechwan pyrethrum, fructus choerospondiatis, rue mixed serum are collected, it is spare.
(4) pearl, assistant too mixing fine powders are prepared
The pearl got ready, assistant are mixed very much, is placed in enclosed stainless steel ball-grinding machine, is pumped the air in equipment, be filled with nitrogen Gas;Under nitrogen protection, mixture is ground to fineness is 180 mesh, spare.
(5) Semen Strychni (processed) detoxification fine powder is prepared
Steam blasting detoxification.The Semen Strychni (processed) that will be got ready impregnates 45min at a temperature of 17.5 DEG C using enough distilled water;It will Semen Strychni (processed) after immersion is placed in steam blasting equipment, using ratio of water to material 1:5.5, dimension pressure time 145s, steam pressure The parameter of 1.7MPa carries out Steam explosion treatment.
The Semen Strychni (processed) after Steam explosion treatment is placed in liquid nitrogen pulverizer, by material powder while spraying liquid nitrogen Being broken to fineness is 180 mesh, obtains Semen Strychni (processed) detoxification fine powder, spare.Animal experiments show that Semen Strychni (processed) detoxification fine powder is to test Small white mouse (50) do not have adverse reaction.
(6) water-bindered pill is prepared
By the agalloch eaglewood prepared, cloves, radix aucklandiae, kaempferia galanga mixing fine powders, nutmeg, west szechwan pyrethrum, fructus choerospondiatis, rue mixing slurry Liquid, pearl, assistant too mixing fine powders, Semen Strychni (processed) detoxification fine powder are uniformly mixed, the water-bindered pill are made using medicinal machine for making water-bindered pills, then adopts With 52 DEG C of heated-air dryings to water content 6.5%, fragrant chrysanthemum promoting blood circulation water-bindered pill product is obtained.
Coronary disease and angina pectoris (qi stagnation and blood stasis type) that First People's Hospital is accepted for medical treatment in certain county patient 70, in January, 2013 is extremely In January, 2014 accepts the case being admitted to hospital for medical treatment, is divided into study group and control group according to the difference of patient's therapeutic scheme after being admitted to hospital.Study group Middle male 21, female 14;Age 41~74 years old, average (55.2 ± 4.6) year;The course of disease 1~109 month, average (26.9 ± 22.3) Month.Male 20, female 15 in control group;Age 40~76 years old, average (54.8 ± 4.7) year;It is the course of disease 1~113 month, average (27.2 ± 22.2) moon.The comparing differences such as 2 groups of Genders, age, courses of disease are not statistically significant (P > 0.05), have comparable Property.
It is oral that control group gives pained stator, and 10 mg/ times, 3 times/d.Fragrant chrysanthemum promoting blood circulation produced by the present invention is given by study group The water-bindered pill respectively takes 1 time, 2 tablets/time sooner or later.2 groups of patient's treatments are with 1 month for 1 course for the treatment of.
Study group is effective 19, it is effective 10, invalid 6, aggravate 0;Control group is effective 129, it is effective 9, invalid 14, aggravate 0.
A kind of embodiment two: perfume chrysanthemum promoting blood circulation water-bindered pill and preparation method thereof
It is a kind of perfume chrysanthemum invigorate blood circulation the water-bindered pill, composition of raw materials includes the raw material of following parts by weight: the agalloch eaglewood of 5 parts by weight, 3 parts by weight Pork and beans Cool, 3 parts by weight west szechwan pyrethrums, the cloves of 3 parts by weight, the fructus choerospondiatis of 2 parts by weight, the BAIYUNXIANG of 4 parts by weight, 3 parts by weight Radix aucklandiae, the kaempferia galanga of 3 parts by weight, the pearl of 3 parts by weight, 0.8 parts by weight assistant too, the Semen Strychni (processed) of 0.8 parts by weight.
Preferred embodiment are as follows: the agalloch eaglewood, nutmeg, west szechwan pyrethrum, cloves, fructus choerospondiatis, BAIYUNXIANG, radix aucklandiae, mountain A kind of apple, pearl, assistant too, Semen Strychni (processed) be dried product.
Preparation method includes the preparation of the first mixing fine powders, the preparation of the second mixing fine powders, the preparation of mixed serum, horse processed The preparation of the preparation of money detoxification fine powder and the fragrant chrysanthemum promoting blood circulation water-bindered pill;
The preparation of first mixing fine powders includes: the agalloch eaglewood that will be got ready, cloves, radix aucklandiae and kaempferia galanga mixing, is broken into 10 purposes Particle;Broken particle is placed in liquid nitrogen pulverizer, being crushed to fineness is 170 mesh, obtains the first mixing fine powders, spare;
The preparation of second mixing fine powders includes: that the pearl that will be got ready and Zuo Tai are mixed to get mixed material, is placed in stainless steel In ball-grinding machine, nitrogen is filled with after pumping the air in the ball grinder of stainless steel ball-milling equipment;Under nitrogen protection, by mixture Abrasive lapping to fineness is that 170 mesh obtain the second mixing fine powders, spare;
The preparation of the mixed serum includes: the nutmeg that will be got ready, west szechwan pyrethrum, fructus choerospondiatis and rue mixing, is broken into 10 Purpose hybrid particles, then to hybrid particles carry out 2 freeze thawing treatments, after treatment by after freeze thawing treatment hybrid particles with Distilled water 1:1 in mass ratio mixing, is placed in stainless-steel grinding equipment, and being ground to fineness is 170 mesh;Material after grinding is set 20min is handled in ultrasonic equipment, is then collected and is obtained mixed serum;
The preparation of the Semen Strychni (processed) detoxification fine powder includes: that 5 DEG C of water of Semen Strychni (processed) is impregnated 30min, then to immersion after Semen Strychni (processed) carry out Steam explosion treatment, then the Semen Strychni (processed) after Steam explosion treatment is placed in liquid nitrogen pulverizer and is crushed It is 170 mesh to fineness, obtains vomiting nut detoxification fine powder;
The preparation of the perfume chrysanthemum promoting blood circulation water-bindered pill includes: by the first mixing fine powders, the second mixing fine powders, mixed serum and Semen Strychni (processed) Detoxification fine powder is uniformly mixed, and the water-bindered pill is made using medicinal machine for making water-bindered pills, then obtains perfume (or spice) to water content 5% using 50 DEG C of heated-air dryings Chrysanthemum promoting blood circulation water-bindered pill product.
Preferred embodiment are as follows: the technological parameter of the Steam explosion treatment are as follows: ratio of water to material 1:5, dimension pressure time 90s, Steam pressure 1.5Mpa.
Preferred embodiment are as follows: the frequency of the ultrasonic equipment is 25KHz, power density 0.4W/cm2
Preferred embodiment are as follows: the freeze thawing treatment is that hybrid particles are placed in 2min in liquid nitrogen, and taking-up is placed in 87 DEG C hot wind environment in 2min.
A kind of embodiment three: perfume chrysanthemum promoting blood circulation water-bindered pill and preparation method thereof
It is a kind of perfume chrysanthemum invigorate blood circulation the water-bindered pill, composition of raw materials includes the raw material of following parts by weight: the agalloch eaglewood of 7 parts by weight, 5 parts by weight Pork and beans Cool, 5 parts by weight west szechwan pyrethrums, the cloves of 5 parts by weight, the fructus choerospondiatis of 4 parts by weight, the BAIYUNXIANG of 6 parts by weight, 5 parts by weight Radix aucklandiae, the kaempferia galanga of 5 parts by weight, the pearl of 5 parts by weight, 1.2 parts by weight assistant too, the Semen Strychni (processed) of 1.2 parts by weight.
Preferred embodiment are as follows: the agalloch eaglewood, nutmeg, west szechwan pyrethrum, cloves, fructus choerospondiatis, BAIYUNXIANG, radix aucklandiae, mountain A kind of apple, pearl, assistant too, Semen Strychni (processed) be dried product.
Preparation method includes the preparation of the first mixing fine powders, the preparation of the second mixing fine powders, the preparation of mixed serum, horse processed The preparation of the preparation of money detoxification fine powder and the fragrant chrysanthemum promoting blood circulation water-bindered pill;
The preparation of first mixing fine powders includes: the agalloch eaglewood that will be got ready, cloves, radix aucklandiae and kaempferia galanga mixing, is broken into 12 purposes Particle;Broken particle is placed in liquid nitrogen pulverizer, being crushed to fineness is 200 mesh, obtains the first mixing fine powders, spare;
The preparation of second mixing fine powders includes: that the pearl that will be got ready and Zuo Tai are mixed to get mixed material, is placed in stainless steel In ball-grinding machine, nitrogen is filled with after pumping the air in the ball grinder of stainless steel ball-milling equipment;Under nitrogen protection, by mixture Abrasive lapping to fineness is that 200 mesh obtain the second mixing fine powders, spare;
The preparation of the mixed serum includes: the nutmeg that will be got ready, west szechwan pyrethrum, fructus choerospondiatis and rue mixing, is broken into 12 Purpose hybrid particles, then to hybrid particles carry out 3 freeze thawing treatments, after treatment by after freeze thawing treatment hybrid particles with Distilled water 1:2 in mass ratio mixing, is placed in stainless-steel grinding equipment, and being ground to fineness is 200 mesh;Material after grinding is set 30min is handled in ultrasonic equipment, is then collected and is obtained mixed serum;
The preparation of the Semen Strychni (processed) detoxification fine powder includes: that 30 DEG C of water of Semen Strychni (processed) is impregnated 60min, then to immersion after Semen Strychni (processed) carry out Steam explosion treatment, then the Semen Strychni (processed) after Steam explosion treatment is placed in liquid nitrogen pulverizer and is crushed It is 200 mesh to fineness, obtains vomiting nut detoxification fine powder;
The preparation of the perfume chrysanthemum promoting blood circulation water-bindered pill includes: by the first mixing fine powders, the second mixing fine powders, mixed serum and Semen Strychni (processed) Detoxification fine powder is uniformly mixed, and the water-bindered pill is made using medicinal machine for making water-bindered pills, then obtains perfume (or spice) to water content 8% using 55 DEG C of heated-air dryings Chrysanthemum promoting blood circulation water-bindered pill product.
Preferred embodiment are as follows: the technological parameter of the Steam explosion treatment are as follows: ratio of water to material 1:6, dimension pressure time 180s, steam pressure 1.8Mpa.
Preferred embodiment are as follows: the frequency of the ultrasonic equipment is 35KHz, power density 0.5W/cm2
Preferred embodiment are as follows: the freeze thawing treatment is that hybrid particles are placed in 3min in liquid nitrogen, and taking-up is placed in 93 DEG C hot wind environment in 3min.
As described above is only to be not intended to tool to explain the preferred embodiments of the invention to do any shape to the present invention Limitation in formula should all wrap therefore all have any modification or change for making the related present invention under identical spirit It includes in the scope that the invention is intended to protect.

Claims (6)

  1. The water-bindered pill 1. a kind of perfume chrysanthemum is invigorated blood circulation, it is characterised in that: composition of raw materials includes the raw material of following parts by weight: 5-7 parts by weight are sunk Perfume, the nutmeg of 3-5 parts by weight, the west szechwan pyrethrum of 3-5 parts by weight, the cloves of 3-5 parts by weight, the fructus choerospondiatis of 2-4 parts by weight, 4- The BAIYUNXIANG of 6 parts by weight, the radix aucklandiae of 3-5 parts by weight, the kaempferia galanga of 3-5 parts by weight, the pearl of 3-5 parts by weight, 0.8-1.2 parts by weight Assistant too, the Semen Strychni (processed) of 0.8-1.2 parts by weight.
  2. 2. it is according to claim 1 perfume chrysanthemum invigorate blood circulation the water-bindered pill, it is characterised in that: the agalloch eaglewood, nutmeg, west szechwan pyrethrum, Cloves, fructus choerospondiatis, BAIYUNXIANG, radix aucklandiae, kaempferia galanga, pearl, assistant too, Semen Strychni (processed) be dried product.
  3. 3. a kind of preparation method of the perfume chrysanthemum promoting blood circulation water-bindered pill, it is characterised in that: composition of raw materials is matched using the raw material of claims 1 or 2 Side, preparation method includes the preparation of the first mixing fine powders, the preparation of the second mixing fine powders, the preparation of mixed serum, Semen Strychni (processed) The preparation of the preparation of detoxification fine powder and the fragrant chrysanthemum promoting blood circulation water-bindered pill;
    The preparation of first mixing fine powders includes: the agalloch eaglewood that will be got ready, cloves, radix aucklandiae and kaempferia galanga mixing, is broken into 10-12 mesh Particle;Broken particle is placed in liquid nitrogen pulverizer, being crushed to fineness is 170-200 mesh, the first mixing fine powders are obtained, It is spare;
    The preparation of second mixing fine powders includes: that the pearl that will be got ready and Zuo Tai are mixed to get mixed material, is placed in stainless steel In ball-grinding machine, nitrogen is filled with after pumping the air in the ball grinder of stainless steel ball-milling equipment;Under nitrogen protection, by mixture Abrasive lapping to fineness is that 170-200 mesh obtains the second mixing fine powders, spare;
    The preparation of the mixed serum includes: the nutmeg that will be got ready, west szechwan pyrethrum, fructus choerospondiatis and rue mixing, is broken into 10- Then hybrid particles are carried out 2-3 freeze thawing treatment by the hybrid particles of 12 mesh, after treatment is by the mixing after freeze thawing treatment Grain is mixed with distilled water 1:1-2 in mass ratio, is placed in stainless-steel grinding equipment, and being ground to fineness is 170-200 mesh;It will grinding Material afterwards, which is placed in ultrasonic equipment, handles 20-30min, then collects and obtains mixed serum;
    The preparation of the Semen Strychni (processed) detoxification fine powder includes: that 5-30 DEG C of Semen Strychni (processed) of water is impregnated 30-60min, then right Semen Strychni (processed) after immersion carries out Steam explosion treatment, and the Semen Strychni (processed) after Steam explosion treatment is then placed in liquid nitrogen pulverizer In be crushed to fineness be 170-200 mesh, obtain vomiting nut detoxification fine powder;
    The preparation of the perfume chrysanthemum promoting blood circulation water-bindered pill includes: by the first mixing fine powders, the second mixing fine powders, mixed serum and Semen Strychni (processed) Detoxification fine powder is uniformly mixed, and the water-bindered pill is made using medicinal machine for making water-bindered pills, then using 50-55 DEG C of heated-air drying to water content 5-8%, Obtain fragrant chrysanthemum promoting blood circulation water-bindered pill product.
  4. 4. the preparation method of the perfume chrysanthemum promoting blood circulation water-bindered pill according to claim 3, it is characterised in that: the Steam explosion treatment Technological parameter are as follows: ratio of water to material 1:5-6, dimension pressure time 90-180s, steam pressure 1.5-1.8Mpa.
  5. 5. the preparation method of the perfume chrysanthemum promoting blood circulation water-bindered pill according to claim 3, it is characterised in that: the frequency of the ultrasonic equipment Rate is 25-35KHz, power density 0.4-0.5W/cm2
  6. 6. the preparation method of the perfume chrysanthemum promoting blood circulation water-bindered pill according to claim 3, it is characterised in that: the freeze thawing treatment is will to mix It closes particle and is placed in 2-3min in liquid nitrogen, taking-up is placed in 2-3min in 87-93 DEG C of hot wind environment.
CN201811264572.5A 2018-10-29 2018-10-29 A kind of perfume chrysanthemum promoting blood circulation water-bindered pill and preparation method thereof Pending CN109224018A (en)

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Application publication date: 20190118